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HSD3B2 cDNA ORF clone, Homo sapiens(Human)

Gene Symbol HSD3B2
Entrez Gene ID 3284
Full Name hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 2
Synonyms HSD3B,HSDB,SDR11E2
General protein information
Preferred Names

hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 2

Names

3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase type 2
3 beta-HSD type II
3 beta-hydroxysteroid dehydrogenase type II, delta 5-delta 4-isomerase type II, 3 beta-HSD type II
3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase type II
3-beta-HSD II
3-beta-HSD adrenal and gonadal type
3-beta-hydroxy-5-ene steroid dehydrogenase
3-beta-hydroxy-Delta(5)-steroid dehydrogenase
delta 5-delta 4-isomerase type II
progesterone reductase
short chain dehydrogenase/reductase family 11E, member 2

Gene Type protein-coding
Organism Homo sapiens(Human)
Genome

1

1p12

Summary The protein encoded by this gene is a bifunctional enzyme that catalyzes the oxidative conversion of delta(5)-ene-3-beta-hydroxy steroid, and the oxidative conversion of ketosteroids. It plays a crucial role in the biosynthesis of all classes of hormonal steroids. This gene is predominantly expressed in the adrenals and the gonads. Mutations in this gene are associated with 3-beta-hydroxysteroid dehydrogenase, type II, deficiency. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Oct 2009].
Disorder MIM:

613890


mRNA and Protein(s)

mRNA Protein Name
NM_000198.3 NP_000189.1 3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase type 2
NM_001166120.1 NP_001159592.1 3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase type 2



Rattus norvegicus (Norway rat) Hsd3b NP_001036084.1
Danio rerio (zebrafish) si:rp71-68n21.10 XP_694204.3
Danio rerio (zebrafish) hsd3b1 NP_997962.1
Xenopus tropicalis (tropical clawed frog) LOC100490622 XP_004920800.1
Rattus norvegicus (Norway rat) LOC100911154 XP_006233083.1
Gallus gallus (chicken) HSD3B2 NP_990449.1
Mus musculus (house mouse) Hsd3b1 NP_032319.1
Rattus norvegicus (Norway rat) Hsd3b6 NP_058961.4
Anopheles gambiae (African malaria mosquito) AgaP_AGAP006654 XP_316685.4
Macaca mulatta (rhesus monkey) LOC100424395 XP_002801771.1
Homo sapiens (human) HSD3B2 NP_001159592.1
Pan troglodytes (chimpanzee) HSD3B2 XP_001142555.1
Canis lupus familiaris (dog) HSD3B2 NP_001010954.1
Bos taurus (cattle) HSD3B1 NP_776768.1
Drosophila melanogaster (fruit fly) CG7724 NP_648957.1


Related articles in PubMed

Immunohistochemical analysis of steroidogenic enzymes in ovarian-type stroma of pancreatic mucinous cystic neoplasms: Comparative study of subepithelial stromal cells in intraductal papillary mucinous neoplasms of the pancreas.
Ishida K, Sasano H, Moriya T, Takahashi Y, Sugimoto R, Mue Y, Murakami K, Fujishima F, Nakamura Y, Morikawa T, Motoi F, Suzuki T, Unno M, Sugai T
Pathology international66(5)281-7(2016 May)

A New Homozygous Frameshift Mutation in the HSD3B2 Gene in an Apparently Nonconsanguineous Italian Family.
Bizzarri C, Massimi A, Federici L, Cualbu A, Loche S, Bellincampi L, Bernardini S, Cappa M, Porzio O
Hormone research in paediatrics86(1)53-61(2016)

Severe Salt-Losing 3β-Hydroxysteroid Dehydrogenase Deficiency: Treatment and Outcomes of HSD3B2 c.35G>A Homozygotes.
Benkert AR, Young M, Robinson D, Hendrickson C, Lee PA, Strauss KA
The Journal of clinical endocrinology and metabolism100(8)E1105-15(2015 Aug)

3β-Hydroxysteroid dehydrogenase isoforms in human aldosterone-producing adenoma.
Konosu-Fukaya S, Nakamura Y, Satoh F, Felizola SJ, Maekawa T, Ono Y, Morimoto R, Ise K, Takeda K, Katsu K, Fujishima F, Kasajima A, Watanabe M, Arai Y, Gomez-Sanchez EP, Gomez-Sanchez CE, Doi M, Okamura H, Sasano H
Molecular and cellular endocrinology408205-12(2015 Jun)

Orexin-A stimulates 3β-hydroxysteroid dehydrogenase expression and cortisol production in H295R human adrenocortical cells through the AKT pathway.
Chang X, Zhao Y, Ju S, Guo L
International journal of molecular medicine34(6)1523-8(2014 Dec)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Sequencing analyses indicate homozygous p.W355R mutation at exon 4 of the 3 beta-hydroxysteroid dehydrogenase type II (HSD3beta2) gene in both siblings.
Title: Testicular Adrenal Rest Tumor in Two Brothers with a Novel Mutation in the 3-Beta-Hydroxysteroid Dehydrogenase-2 Gene.

The steroidogenic enzymes cytochrome P450 cholesterol side-chain cleavage enzyme (P450scc), cytochrome P450 17 alpha-hydroxylase (P450c17) and 3beta-hydroxysteroid dehydrogenase (3beta-HSD) showed immunoreactivity in 9/20 (45.0 %), 15/20 (75.0 %) and 13/20 (65.0 %), respectively, of ovarian-type stroma from pancreatic mucinous cystic neoplasm cases.
Title: Immunohistochemical analysis of steroidogenic enzymes in ovarian-type stroma of pancreatic mucinous cystic neoplasms: Comparative study of subepithelial stromal cells in intraductal papillary mucinous neoplasms of the pancreas.

the first HSD3B2 gene mutation in the Italian population and analyzed its effect in the context of the 3beta-HSD2 structure and function.
Title: A New Homozygous Frameshift Mutation in the HSD3B2 Gene in an Apparently Nonconsanguineous Italian Family.

Patients with HSD3B2 deficiency and 21-hydroxylase deficiency suffer similar morbid complications from under- and overtreatment, but HSD3B2 deficiency is associated with a distinctive pattern of sex steroid dysmetabolism.
Title: Severe Salt-Losing 3β-Hydroxysteroid Dehydrogenase Deficiency: Treatment and Outcomes of HSD3B2 c.35G>A Homozygotes.

HSD3B1 is involved in aldosterone production, despite its lower levels of expression compared with HSD3B2, and also possibly associated with KCNJ5 mutation in aldosterone-producing adenoma.
Title: 3β-Hydroxysteroid dehydrogenase isoforms in human aldosterone-producing adenoma.

The following HSD3B2 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the HSD3B2 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

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***CloneID RefSeq Accession Definition **Vector *Turnaround time Price (USD) Select
OHu14034 NM_001166120.1
Latest version!
Homo sapiens hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 2 (HSD3B2), transcript variant 2, mRNA. pcDNA3.1+/C-(K)DYK or customized vector
in pcDNA3.1+/C-(K)DYK
$189.50-$265.30
$379.00
OHu14034 NM_000198.3
Latest version!
Homo sapiens hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 2 (HSD3B2), transcript variant 1, mRNA. pcDNA3.1+/C-(K)DYK or customized vector
in pcDNA3.1+/C-(K)DYK
$189.50-$265.30
$379.00

ORF Online Only Promotion

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.


CloneID OHu14034
Clone ID Related Accession (Same CDS sequence) NM_000198.3 , NM_001166120.1
Accession Version NM_000198.3 Latest version! Documents for ORF clone product in dufault vector
Sequence Information ORF Nucleotide Sequence (Length: 1119bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags COA
ORF Insert Method CloneEZ® Seamless cloning technology
Insert Structure linear
Update Date 2017-05-07
Organism Homo sapiens(Human)
Product 3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase type 2
Comment REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AV705363.1, BC038419.1 and AK222997.1. On Oct 8, 2009 this sequence version replaced NM_000198.2. Transcript Variant: This variant (1) represents the predominant transcript. Variants 1 and 2 encode the same protein. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AK222997.1, BC038419.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1968540, SAMEA1968968 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
ATGGGCTGGA GCTGCCTTGT GACAGGAGCA GGAGGGCTTC TGGGTCAGAG GATCGTCCGC 
CTGTTGGTGG AAGAGAAGGA ACTGAAGGAG ATCAGGGCCT TGGACAAGGC CTTCAGACCA
GAATTGAGAG AGGAATTTTC TAAGCTCCAG AACAGGACCA AGCTGACTGT ACTTGAAGGA
GACATTCTGG ATGAGCCATT CCTGAAAAGA GCCTGCCAGG ACGTCTCGGT CGTCATCCAC
ACCGCCTGTA TCATTGATGT CTTTGGTGTC ACTCACAGAG AGTCCATCAT GAATGTCAAT
GTGAAAGGTA CCCAGCTACT GTTGGAGGCC TGTGTCCAAG CCAGTGTGCC AGTCTTCATC
TACACCAGTA GCATAGAGGT AGCCGGGCCC AACTCCTACA AGGAAATCAT CCAGAACGGC
CACGAAGAAG AGCCTCTGGA AAACACATGG CCCACTCCAT ACCCGTACAG CAAAAAGCTT
GCTGAGAAGG CTGTGCTGGC GGCTAATGGG TGGAATCTAA AAAATGGTGA TACCTTGTAC
ACTTGTGCGT TAAGACCCAC ATATATCTAT GGGGAAGGAG GCCCATTCCT TTCTGCCAGT
ATAAATGAGG CCCTGAACAA CAATGGGATC CTGTCAAGTG TTGGAAAGTT CTCTACAGTC
AACCCAGTCT ATGTTGGCAA CGTGGCCTGG GCCCACATTC TGGCCTTGAG GGCTCTGCGG
GACCCCAAGA AGGCCCCAAG TGTCCGAGGT CAATTCTATT ACATCTCAGA TGACACGCCT
CACCAAAGCT ATGATAACCT TAATTACATC CTGAGCAAAG AGTTTGGCCT CCGCCTTGAT
TCCAGATGGA GCCTTCCTTT AACCCTGATG TACTGGATTG GCTTCCTGCT GGAAGTAGTG
AGCTTCCTAC TCAGCCCAAT TTACTCCTAT CAACCCCCCT TCAACCGCCA CACAGTCACA
TTATCAAATA GTGTGTTCAC CTTCTCTTAC AAGAAGGCTC AGCGAGATCT GGCGTATAAG
CCACTCTACA GCTGGGAGGA AGCCAAGCAG AAAACCGTGG AGTGGGTTGG TTCCCTTGTG
GACCGGCACA AGGAGACCCT GAAGTCCAAG ACTCAGTGA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq NP_000189.1
CDS173..1291
Misc Feature(1)38..40
Misc Feature(2)182..1240
Misc Feature(3)188..1030
Misc Feature(4)order(197..199,203..214,275..283,413..421,467..469,536..544,632..634,644..646,728..739)
Misc Feature(5)order(470..472,542..544,632..634,644..646)
Misc Feature(6)order(542..544,632..634,734..736,773..775,803..805,818..820)
Misc Feature(7)1031..1093
Exon (1)1..83
Exon (2)84..314
Exon (3)315..479
Exon (4)480..1710
Translation

Target ORF information:

RefSeq Version NM_000198.3
Organism Homo sapiens(Human)
Definition Homo sapiens hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 2 (HSD3B2), transcript variant 1, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
NM_000198.3

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
ATGGGCTGGA GCTGCCTTGT GACAGGAGCA GGAGGGCTTC TGGGTCAGAG GATCGTCCGC 
CTGTTGGTGG AAGAGAAGGA ACTGAAGGAG ATCAGGGCCT TGGACAAGGC CTTCAGACCA
GAATTGAGAG AGGAATTTTC TAAGCTCCAG AACAGGACCA AGCTGACTGT ACTTGAAGGA
GACATTCTGG ATGAGCCATT CCTGAAAAGA GCCTGCCAGG ACGTCTCGGT CGTCATCCAC
ACCGCCTGTA TCATTGATGT CTTTGGTGTC ACTCACAGAG AGTCCATCAT GAATGTCAAT
GTGAAAGGTA CCCAGCTACT GTTGGAGGCC TGTGTCCAAG CCAGTGTGCC AGTCTTCATC
TACACCAGTA GCATAGAGGT AGCCGGGCCC AACTCCTACA AGGAAATCAT CCAGAACGGC
CACGAAGAAG AGCCTCTGGA AAACACATGG CCCACTCCAT ACCCGTACAG CAAAAAGCTT
GCTGAGAAGG CTGTGCTGGC GGCTAATGGG TGGAATCTAA AAAATGGTGA TACCTTGTAC
ACTTGTGCGT TAAGACCCAC ATATATCTAT GGGGAAGGAG GCCCATTCCT TTCTGCCAGT
ATAAATGAGG CCCTGAACAA CAATGGGATC CTGTCAAGTG TTGGAAAGTT CTCTACAGTC
AACCCAGTCT ATGTTGGCAA CGTGGCCTGG GCCCACATTC TGGCCTTGAG GGCTCTGCGG
GACCCCAAGA AGGCCCCAAG TGTCCGAGGT CAATTCTATT ACATCTCAGA TGACACGCCT
CACCAAAGCT ATGATAACCT TAATTACATC CTGAGCAAAG AGTTTGGCCT CCGCCTTGAT
TCCAGATGGA GCCTTCCTTT AACCCTGATG TACTGGATTG GCTTCCTGCT GGAAGTAGTG
AGCTTCCTAC TCAGCCCAAT TTACTCCTAT CAACCCCCCT TCAACCGCCA CACAGTCACA
TTATCAAATA GTGTGTTCAC CTTCTCTTAC AAGAAGGCTC AGCGAGATCT GGCGTATAAG
CCACTCTACA GCTGGGAGGA AGCCAAGCAG AAAACCGTGG AGTGGGTTGG TTCCCTTGTG
GACCGGCACA AGGAGACCCT GAAGTCCAAG ACTCAGTGA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OHu14034
Clone ID Related Accession (Same CDS sequence) NM_000198.3 , NM_001166120.1
Accession Version NM_001166120.1 Latest version! Documents for ORF clone product in dufault vector
Sequence Information ORF Nucleotide Sequence (Length: 1119bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags COA
ORF Insert Method CloneEZ® Seamless cloning technology
Insert Structure linear
Update Date 2017-05-07
Organism Homo sapiens(Human)
Product 3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase type 2
Comment REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from BP197992.1, BC038419.1 and AK222997.1. This sequence is a reference standard in the RefSeqGene project. Transcript Variant: This variant (2) contains an alternate 5' non-coding exon, hence differs in the 5' UTR compared to variant 1. Variants 1 and 2 encode the same protein. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: DA015880.1, DA432316.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2145544, SAMEA2146411 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
ATGGGCTGGA GCTGCCTTGT GACAGGAGCA GGAGGGCTTC TGGGTCAGAG GATCGTCCGC 
CTGTTGGTGG AAGAGAAGGA ACTGAAGGAG ATCAGGGCCT TGGACAAGGC CTTCAGACCA
GAATTGAGAG AGGAATTTTC TAAGCTCCAG AACAGGACCA AGCTGACTGT ACTTGAAGGA
GACATTCTGG ATGAGCCATT CCTGAAAAGA GCCTGCCAGG ACGTCTCGGT CGTCATCCAC
ACCGCCTGTA TCATTGATGT CTTTGGTGTC ACTCACAGAG AGTCCATCAT GAATGTCAAT
GTGAAAGGTA CCCAGCTACT GTTGGAGGCC TGTGTCCAAG CCAGTGTGCC AGTCTTCATC
TACACCAGTA GCATAGAGGT AGCCGGGCCC AACTCCTACA AGGAAATCAT CCAGAACGGC
CACGAAGAAG AGCCTCTGGA AAACACATGG CCCACTCCAT ACCCGTACAG CAAAAAGCTT
GCTGAGAAGG CTGTGCTGGC GGCTAATGGG TGGAATCTAA AAAATGGTGA TACCTTGTAC
ACTTGTGCGT TAAGACCCAC ATATATCTAT GGGGAAGGAG GCCCATTCCT TTCTGCCAGT
ATAAATGAGG CCCTGAACAA CAATGGGATC CTGTCAAGTG TTGGAAAGTT CTCTACAGTC
AACCCAGTCT ATGTTGGCAA CGTGGCCTGG GCCCACATTC TGGCCTTGAG GGCTCTGCGG
GACCCCAAGA AGGCCCCAAG TGTCCGAGGT CAATTCTATT ACATCTCAGA TGACACGCCT
CACCAAAGCT ATGATAACCT TAATTACATC CTGAGCAAAG AGTTTGGCCT CCGCCTTGAT
TCCAGATGGA GCCTTCCTTT AACCCTGATG TACTGGATTG GCTTCCTGCT GGAAGTAGTG
AGCTTCCTAC TCAGCCCAAT TTACTCCTAT CAACCCCCCT TCAACCGCCA CACAGTCACA
TTATCAAATA GTGTGTTCAC CTTCTCTTAC AAGAAGGCTC AGCGAGATCT GGCGTATAAG
CCACTCTACA GCTGGGAGGA AGCCAAGCAG AAAACCGTGG AGTGGGTTGG TTCCCTTGTG
GACCGGCACA AGGAGACCCT GAAGTCCAAG ACTCAGTGA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq NP_001159592.1
CDS250..1368
Misc Feature(1)82..84
Misc Feature(2)259..1317
Misc Feature(3)265..1107
Misc Feature(4)order(274..276,280..291,352..360,490..498,544..546,613..621,709..711,721..723,805..816)
Misc Feature(5)order(547..549,619..621,709..711,721..723)
Misc Feature(6)order(619..621,709..711,811..813,850..852,880..882,895..897)
Misc Feature(7)1108..1170
Exon (1)1..160
Exon (2)161..391
Exon (3)392..556
Exon (4)557..1787
Translation

Target ORF information:

RefSeq Version NM_001166120.1
Organism Homo sapiens(Human)
Definition Homo sapiens hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 2 (HSD3B2), transcript variant 2, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
NM_001166120.1

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
ATGGGCTGGA GCTGCCTTGT GACAGGAGCA GGAGGGCTTC TGGGTCAGAG GATCGTCCGC 
CTGTTGGTGG AAGAGAAGGA ACTGAAGGAG ATCAGGGCCT TGGACAAGGC CTTCAGACCA
GAATTGAGAG AGGAATTTTC TAAGCTCCAG AACAGGACCA AGCTGACTGT ACTTGAAGGA
GACATTCTGG ATGAGCCATT CCTGAAAAGA GCCTGCCAGG ACGTCTCGGT CGTCATCCAC
ACCGCCTGTA TCATTGATGT CTTTGGTGTC ACTCACAGAG AGTCCATCAT GAATGTCAAT
GTGAAAGGTA CCCAGCTACT GTTGGAGGCC TGTGTCCAAG CCAGTGTGCC AGTCTTCATC
TACACCAGTA GCATAGAGGT AGCCGGGCCC AACTCCTACA AGGAAATCAT CCAGAACGGC
CACGAAGAAG AGCCTCTGGA AAACACATGG CCCACTCCAT ACCCGTACAG CAAAAAGCTT
GCTGAGAAGG CTGTGCTGGC GGCTAATGGG TGGAATCTAA AAAATGGTGA TACCTTGTAC
ACTTGTGCGT TAAGACCCAC ATATATCTAT GGGGAAGGAG GCCCATTCCT TTCTGCCAGT
ATAAATGAGG CCCTGAACAA CAATGGGATC CTGTCAAGTG TTGGAAAGTT CTCTACAGTC
AACCCAGTCT ATGTTGGCAA CGTGGCCTGG GCCCACATTC TGGCCTTGAG GGCTCTGCGG
GACCCCAAGA AGGCCCCAAG TGTCCGAGGT CAATTCTATT ACATCTCAGA TGACACGCCT
CACCAAAGCT ATGATAACCT TAATTACATC CTGAGCAAAG AGTTTGGCCT CCGCCTTGAT
TCCAGATGGA GCCTTCCTTT AACCCTGATG TACTGGATTG GCTTCCTGCT GGAAGTAGTG
AGCTTCCTAC TCAGCCCAAT TTACTCCTAT CAACCCCCCT TCAACCGCCA CACAGTCACA
TTATCAAATA GTGTGTTCAC CTTCTCTTAC AAGAAGGCTC AGCGAGATCT GGCGTATAAG
CCACTCTACA GCTGGGAGGA AGCCAAGCAG AAAACCGTGG AGTGGGTTGG TTCCCTTGTG
GACCGGCACA AGGAGACCCT GAAGTCCAAG ACTCAGTGA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

book

Immunohistochemical analysis of steroidogenic enzymes in ovarian-type stroma of pancreatic mucinous cystic neoplasms: Comparative study of subepithelial stromal cells in intraductal papillary mucinous neoplasms of the pancreas.
Pathology international66(5)281-7(2016 May)
Ishida K,Sasano H,Moriya T,Takahashi Y,Sugimoto R,Mue Y,Murakami K,Fujishima F,Nakamura Y,Morikawa T,Motoi F,Suzuki T,Unno M,Sugai T


book

A New Homozygous Frameshift Mutation in the HSD3B2 Gene in an Apparently Nonconsanguineous Italian Family.
Hormone research in paediatrics86(1)53-61(2016)
Bizzarri C,Massimi A,Federici L,Cualbu A,Loche S,Bellincampi L,Bernardini S,Cappa M,Porzio O


book

Severe Salt-Losing 3β-Hydroxysteroid Dehydrogenase Deficiency: Treatment and Outcomes of HSD3B2 c.35G>A Homozygotes.
The Journal of clinical endocrinology and metabolism100(8)E1105-15(2015 Aug)
Benkert AR,Young M,Robinson D,Hendrickson C,Lee PA,Strauss KA


book

3β-Hydroxysteroid dehydrogenase isoforms in human aldosterone-producing adenoma.
Molecular and cellular endocrinology408205-12(2015 Jun)
Konosu-Fukaya S,Nakamura Y,Satoh F,Felizola SJ,Maekawa T,Ono Y,Morimoto R,Ise K,Takeda K,Katsu K,Fujishima F,Kasajima A,Watanabe M,Arai Y,Gomez-Sanchez EP,Gomez-Sanchez CE,Doi M,Okamura H,Sasano H


book

Orexin-A stimulates 3β-hydroxysteroid dehydrogenase expression and cortisol production in H295R human adrenocortical cells through the AKT pathway.
International journal of molecular medicine34(6)1523-8(2014 Dec)
Chang X,Zhao Y,Ju S,Guo L


 
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