Gene Symbol | IFNA4 |
Entrez Gene ID | 3441 |
Full Name | interferon alpha 4 |
Synonyms | IFN-alpha4a,INFA4 |
General protein information |
|
Gene Type | protein-coding |
Organism | Homo sapiens(human) |
Genome | |
Disorder MIM: |
ORF » Species Summary » Homo sapiens » IFNA4 cDNA ORF clone
Gene Symbol | IFNA4 |
Entrez Gene ID | 3441 |
Full Name | interferon alpha 4 |
Synonyms | IFN-alpha4a,INFA4 |
General protein information |
|
Gene Type | protein-coding |
Organism | Homo sapiens(human) |
Genome | |
Disorder MIM: |
mRNA | Protein | Name |
---|---|---|
NM_021068.2 | NP_066546.1 | interferon alpha-4 precursor |
NM_021068.3 | NP_066546.1 | interferon alpha-4 precursor |
Homo sapiens (human) | IFNA4 | NP_066546.1 |
Mus musculus (house mouse) | Ifna2 | NP_034633.2 |
Mus musculus (house mouse) | Ifna6 | NP_996754.1 |
Mus musculus (house mouse) | Ifna5 | NP_034635.2 |
Mus musculus (house mouse) | Ifna14 | NP_996858.1 |
Mus musculus (house mouse) | Gm13280 | NP_996750.1 |
Rattus norvegicus (Norway rat) | RGD1564897 | XP_578467.1 |
Rattus norvegicus (Norway rat) | Ifna4 | NP_001100137.1 |
Rattus norvegicus (Norway rat) | LOC100912314 | XP_003750022.1 |
Rattus norvegicus (Norway rat) | Ifna16l1 | XP_575856.1 |
IFNA10 | XP_001107693.1 | |
Mus musculus (house mouse) | Ifna1 | NP_034632.2 |
Mus musculus (house mouse) | Ifna13 | NP_796321.1 |
Rattus norvegicus (Norway rat) | RGD1559679 | XP_578466.2 |
Rattus norvegicus (Norway rat) | Ifna11 | XP_233150.2 |
Mus musculus (house mouse) | Ifnab | NP_032362.2 |
Mus musculus (house mouse) | Ifna12 | NP_796335.1 |
Rattus norvegicus (Norway rat) | LOC100912356 | XP_003750023.1 |
Mus musculus (house mouse) | Ifna11 | NP_032359.2 |
Mus musculus (house mouse) | Ifna9 | NP_034637.1 |
Rattus norvegicus (Norway rat) | Ifna1 | NP_001014786.1 |
Pan troglodytes (chimpanzee) | IFNA17 | XP_001151758.1 |
Mus musculus (house mouse) | Gm12597 | NP_996753.1 |
Mus musculus (house mouse) | Ifna7 | NP_032360.2 |
Rattus norvegicus (Norway rat) | Ifna2 | NP_001258147.1 |
Exome sequencing identifies novel compound heterozygous IFNA4 and IFNA10 mutations as a cause of impaired function in Crohn's disease patients.
Xiao CX, Xiao JJ, Xu HZ, Wang HH, Chen X, Liu YS, Li P, Shi Y, Nie YZ, Li S, Wu KC, Liu ZJ, Ren JL, Guleng B
Scientific reports510514(2015 May)
Dengue hemorrhagic fever is associated with polymorphisms in JAK1.
Silva LK, Blanton RE, Parrado AR, Melo PS, Morato VG, Reis EA, Dias JP, Castro JM, Vasconcelos PF, Goddard KA, Barreto ML, Reis MG, Teixeira MG
European journal of human genetics : EJHG18(11)1221-7(2010 Nov)
New genetic associations detected in a host response study to hepatitis B vaccine.
Davila S, Froeling FE, Tan A, Bonnard C, Boland GJ, Snippe H, Hibberd ML, Seielstad M
Genes and immunity11(3)232-8(2010 Apr)
Induction of suppressor of cytokine signaling-3 by herpes simplex virus type 1 contributes to inhibition of the interferon signaling pathway.
Yokota S, Yokosawa N, Okabayashi T, Suzutani T, Miura S, Jimbow K, Fujii N
Journal of virology78(12)6282-6(2004 Jun)
DNA sequence and analysis of human chromosome 9.
Humphray SJ, Oliver K, Hunt AR, Plumb RW, Loveland JE, Howe KL, Andrews TD, Searle S, Hunt SE, Scott CE, Jones MC, Ainscough R, Almeida JP, Ambrose KD, Ashwell RI, Babbage AK, Babbage S, Bagguley CL, Bailey J, Banerjee R, Barker DJ, Barlow KF, Bates K, Beasley H, Beasley O, Bird CP, Bray-Allen S, Brown AJ, Brown JY, Burford D, Burrill W, Burton J, Carder C, Carter NP, Chapman JC, Chen Y, Clarke G, Clark SY, Clee CM, Clegg S, Collier RE, Corby N, Crosier M, Cummings AT, Davies J, Dhami P, Dunn M, Dutta I, Dyer LW, Earthrowl ME, Faulkner L, Fleming CJ, Frankish A, Frankland JA, French L, Fricker DG, Garner P, Garnett J, Ghori J, Gilbert JG, Glison C, Grafham DV, Gribble S, Griffiths C, Griffiths-Jones S, Grocock R, Guy J, Hall RE, Hammond S, Harley JL, Harrison ES, Hart EA, Heath PD, Henderson CD, Hopkins BL, Howard PJ, Howden PJ, Huckle E, Johnson C, Johnson D, Joy AA, Kay M, Keenan S, Kershaw JK, Kimberley AM, King A, Knights A, Laird GK, Langford C, Lawlor S, Leongamornlert DA, Leversha M, Lloyd C, Lloyd DM, Lovell J, Martin S, Mashreghi-Mohammadi M, Matthews L, McLaren S, McLay KE, McMurray A, Milne S, Nickerson T, Nisbett J, Nordsiek G, Pearce AV, Peck AI, Porter KM, Pandian R, Pelan S, Phillimore B, Povey S, Ramsey Y, Rand V, Scharfe M, Sehra HK, Shownkeen R, Sims SK, Skuce CD, Smith M, Steward CA, Swarbreck D, Sycamore N, Tester J, Thorpe A, Tracey A, Tromans A, Thomas DW, Wall M, Wallis JM, West AP, Whitehead SL, Willey DL, Williams SA, Wilming L, Wray PW, Young L, Ashurst JL, Coulson A, Bl?cker H, Durbin R, Sulston JE, Hubbard T, Jackson MJ, Bentley DR, Beck S, Rogers J, Dunham I
Nature429(6990)369-74(2004 May)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
Heterozygous IFNA4 variants is a cause of impaired function and CD-susceptibility genes in Chinese individuals from multiple center based study.
Title: Exome sequencing identifies novel compound heterozygous IFNA4 and IFNA10 mutations as a cause of impaired function in Crohn's disease patients.
Observational study of gene-disease association. (HuGE Navigator)
Title: Dengue hemorrhagic fever is associated with polymorphisms in JAK1.
Observational study of gene-disease association. (HuGE Navigator)
Title: New genetic associations detected in a host response study to hepatitis B vaccine.
suppression of IFN signaling and IFN production by SOC3 occurs during HSV-1 infection
Title: Induction of suppressor of cytokine signaling-3 by herpes simplex virus type 1 contributes to inhibition of the interferon signaling pathway.
Alpha interferon suppresses the cyclin D3 and cdc25A genes, leading to a reversible G0-like arrest.
Title: Alpha interferon suppresses the cyclin D3 and cdc25A genes, leading to a reversible G0-like arrest.
The following IFNA4 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the IFNA4 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
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CloneID | OHu24435 | |
Clone ID Related Accession (Same CDS sequence) | NM_021068.2 , NM_021068.3 | |
Accession Version | NM_021068.2 | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 570bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-05-03 | |
Organism | Homo sapiens(human) | |
Product | interferon alpha-4 precursor | |
Comment | Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from M27318.1 and AL512606.6. On Oct 11, 2008 this sequence version replaced NM_021068.1. Sequence Note: This RefSeq record was created from transcript and genomic sequence data because no single transcript was available for the full length of the gene. The extent of this transcript is supported by transcript alignments and experimental data. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##RefSeq-Attributes-START## RefSeq Select criteria :: based on single protein-coding transcript ##RefSeq-Attributes-END## |
1 | ATGGCCCTGT CCTTTTCTTT ACTGATGGCC GTGCTGGTGC TCAGCTACAA ATCCATCTGT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_066546.1 |
CDS | 69..638 |
Translation |
Target ORF information:
Target ORF information:
|
NM_021068.2 |
1 | ATGGCCCTGT CCTTTTCTTT ACTGATGGCC GTGCTGGTGC TCAGCTACAA ATCCATCTGT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OHu24435 | |
Clone ID Related Accession (Same CDS sequence) | NM_021068.2 , NM_021068.3 | |
Accession Version | NM_021068.3 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 570bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2020-01-04 | |
Organism | Homo sapiens(human) | |
Product | interferon alpha-4 precursor | |
Comment | Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AL512606.6. On Nov 26, 2019 this sequence version replaced NM_021068.2. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript is intronless :: M27318.1, BC113642.1 [ECO:0000345] ##Evidence-Data-END## ##RefSeq-Attributes-START## RefSeq Select criteria :: based on single protein-coding transcript ##RefSeq-Attributes-END## |
1 | ATGGCCCTGT CCTTTTCTTT ACTGATGGCC GTGCTGGTGC TCAGCTACAA ATCCATCTGT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_066546.1 |
CDS | 152..721 |
Translation |
Target ORF information:
Target ORF information:
|
NM_021068.3 |
1 | ATGGCCCTGT CCTTTTCTTT ACTGATGGCC GTGCTGGTGC TCAGCTACAA ATCCATCTGT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
Exome sequencing identifies novel compound heterozygous IFNA4 and IFNA10 mutations as a cause of impaired function in Crohn's disease patients. |
Dengue hemorrhagic fever is associated with polymorphisms in JAK1. |
New genetic associations detected in a host response study to hepatitis B vaccine. |
Induction of suppressor of cytokine signaling-3 by herpes simplex virus type 1 contributes to inhibition of the interferon signaling pathway. |
DNA sequence and analysis of human chromosome 9. |