×

TUBB8 cDNA ORF clone, Homo sapiens(Human)

Gene Symbol TUBB8
Entrez Gene ID 347688
Full Name tubulin beta 8 class VIII
Synonyms OOMD,OOMD2,bA631M21.2
General protein information
Preferred Names

tubulin beta 8 class VIII

Names

tubulin beta-8 chain
HSA10p15 beta-tubulin 4Q

Gene Type protein-coding
Organism Homo sapiens(Human)
Genome

10

10p15.3

Summary The protein encoded by this gene represents the primary beta-tubulin subunit of oocytes and the early embryo. Defects in this gene, which is primate-specific, are a cause of oocyte maturation defect 2 and infertility. [provided by RefSeq, Mar 2016].
Disorder MIM:

616768


mRNA and Protein(s)

mRNA Protein Name
XM_017016193.1 XP_016871682.1 tubulin beta-8 chain isoform X1
NM_177987.2 NP_817124.1 tubulin beta-8 chain
XM_017016192.1 XP_016871681.1 tubulin beta-8 chain isoform X1
XM_011519459.2 XP_011517761.1 tubulin beta-8 chain isoform X3
XM_011519460.2 XP_011517762.1 tubulin beta-8 chain isoform X2



Homo sapiens (human) TUBB8 NP_817124.1
Macaca mulatta (rhesus monkey) LOC715011 XP_001104203.1
Pan troglodytes (chimpanzee) TUBB8 XP_001135050.1


Related articles in PubMed

Mutations in TUBB8 and Human Oocyte Meiotic Arrest.
Feng R, Sang Q, Kuang Y, Sun X, Yan Z, Zhang S, Shi J, Tian G, Luchniak A, Fukuda Y, Li B, Yu M, Chen J, Xu Y, Guo L, Qu R, Wang X, Sun Z, Liu M, Shi H, Wang H, Feng Y, Shao R, Chai R, Li Q, Xing Q, Zhang R, Nogales E, Jin L, He L, Gupta ML Jr, Cowan NJ, Wang L
The New England journal of medicine374(3)223-32(2016 Jan)

A cascade of complex subtelomeric duplications during the evolution of the hominoid and Old World monkey genomes.
van Geel M, Eichler EE, Beck AF, Shan Z, Haaf T, van der Maarel SM, Frants RR, de Jong PJ
American journal of human genetics70(1)269-78(2002 Jan)

Identification of a novel beta-tubulin subfamily with one member (TUBB4Q) located near the telomere of chromosome region 4q35.
van Geel M, van Deutekom JC, van Staalduinen A, Lemmers RJ, Dickson MC, Hofker MH, Padberg GW, Hewitt JE, de Jong PJ, Frants RR
Cytogenetics and cell genetics88(3-4)316-21(2000)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following TUBB8 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the TUBB8 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

Online Only Promotion

Up to 50% OFF! Starting
from $49/clone

***CloneID RefSeq Accession Definition **Vector *Turnaround time Price (USD) Select
OHu10611 NM_177987.2
Latest version!
Homo sapiens tubulin beta 8 class VIII (TUBB8), mRNA. pcDNA3.1+/C-(K)DYK or customized vector
in pcDNA3.1+/C-(K)DYK
$159.50-$223.30
$319.00
OHu79487 XM_011519459.2
Latest version!
Homo sapiens tubulin beta 8 class VIII (TUBB8), transcript variant X4, mRNA. pcDNA3.1+/C-(K)DYK or customized vector 5-7 $223.30
$319.00
OHu79488 XM_011519460.2
Latest version!
Homo sapiens tubulin beta 8 class VIII (TUBB8), transcript variant X3, mRNA. pcDNA3.1+/C-(K)DYK or customized vector 7-9 $139.30
$199.00
OHu91381 XM_017016192.1
Latest version!
Homo sapiens tubulin beta 8 class VIII (TUBB8), transcript variant X1, mRNA. pcDNA3.1+/C-(K)DYK or customized vector 7-9 $139.30
$199.00
OHu91381 XM_017016193.1
Latest version!
Homo sapiens tubulin beta 8 class VIII (TUBB8), transcript variant X2, mRNA. pcDNA3.1+/C-(K)DYK or customized vector 7-9 $139.30
$199.00

ORF Online Only Promotion

Next-day Shipping ORF Clones ( in default vector with tag)
1 Clone 30% OFF
2-4 Clone 40% OFF
5 or more Clone 50% OFF
All Other ORF Clones
30% OFF

*Business Day

** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.


CloneID OHu10611
Clone ID Related Accession (Same CDS sequence) NM_177987.2
Accession Version NM_177987.2 Latest version! Documents for ORF clone product in dufault vector
Sequence Information ORF Nucleotide Sequence (Length: 1335bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags COA
ORF Insert Method CloneEZ® Seamless cloning technology
Insert Structure linear
Update Date 2016-03-18
Organism Homo sapiens(Human)
Product tubulin beta-8 chain
Comment REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AL713922.12. This sequence is a reference standard in the RefSeqGene project. On Aug 13, 2009 this sequence version replaced NM_177987.1. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. ##Evidence-Data-START## Transcript exon combination :: BC101271.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2158188 [ECO:0000348] ##Evidence-Data-END##

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
ATGAGGGAGA TCGTGCTCAC GCAGATCGGG CAGTGCGGGA ATCAGATCGG CGCCAAGTTC 
TGGGAGGTGA TCTCTGATGA ACATGCCATC GACTCCGCTG GCACCTACCA CGGGGACAGC
CACCTGCAGC TGGAGCGCAT CAACGTGTAC TACAACGAGG CCAGCGGTGG CAGGTACGTG
CCCCGCGCTG TGCTCGTGGA TCTGGAGCCG GGCACCATGG ACTCTGTGCG CTCGGGGCCC
TTCGGGCAGG TCTTCAGGCC AGACAACTTC ATCTTCGGTC AGTGTGGGGC CGGAAACAAC
TGGGCCAAGG GACACTACAC CGAAGGCGCG GAGCTGATGG AGTCAGTGAT GGACGTTGTC
AGAAAGGAGG CTGAGAGCTG TGACTGCCTG CAGGGTTTCC AGCTGACCCA CTCCCTGGGT
GGGGGGACTG GGTCTGGGAT GGGTACCCTT CTGCTCAGTA AGATCCGGGA GGAGTACCCA
GACAGGATCA TAAACACATT CAGCATCCTG CCCTCGCCCA AGGTGTCGGA CACCGTGGTG
GAGCCCTACA ACGCCACCCT CTCAGTCCAC CAGCTCATAG AAAACGCAGA TGAGACCTTT
TGCATAGATA ACGAAGCTCT GTATGACATA TGTTCCAAGA CCCTAAAACT GCCCACACCC
ACCTATGGTG ACCTGAACCA CCTGGTGTCT GCTACCATGA GTGGGGTCAC CACGTGCCTG
CGCTTCCCGG GCCAGCTGAA TGCTGACCTG CGGAAGCTGG CCGTGAACAT GGTCCCGTTT
CCCCGGCTGC ATTTCTTCAT GCCCGGCTTT GCCCCACTGA CCAGCCGGGG CAGCCAGCAG
TACCGGGCCT TGACTGTGGC TGAGCTTACC CAGCAGATGT TTGATGCTAA GAACATGATG
GCTGCCTGTG ACCCCCGTCA CGGCCGCTAC CTAACGGCGG CTGCCATTTT CAGGGGTCGC
ATGCCCATGA GGGAGGTGGA TGAACAAATG TTCAACATTC AAGATAAGAA CAGCAGTTAC
TTTGCTGACT GGCTCCCCAA CAACGTAAAA ACAGCCGTCT GTGACATCCC ACCCCGGGGG
CTAAAAATGT CAGCCACCTT CATTGGGAAT AATACGGCCA TCCAGGAACT CTTCAAGCGT
GTCTCAGAGC AGTTTACAGC AATGTTCAGG CGCAAGGCCT TCCTCCACTG GTACACGGGC
GAGGGCATGG ATGAGATGGA ATTCACCGAG GCCGAGAGCA ACATGAACGA CCTGGTGTCT
GAATATCAGC AATATCAGGA TGCCACGGCC GAGGAGGAGG AGGATGAGGA GTATGCCGAG
GAGGAGGTGG CCTAG

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq NP_817124.1
CDS1..1335
Misc Feature(1)1..1281
Misc Feature(2)4..1278
Misc Feature(3)order(4..6,391..393,733..741,751..753,766..768,772..780,964..972,979..981,1039..1053)
Misc Feature(4)order(28..36,43..45,412..414,418..432,541..543,610..612,664..666,676..678)
Misc Feature(5)order(64..69,76..81,643..645,670..672,679..684,700..702,808..810,814..822,1072..1080)
Misc Feature(6)118..120
Misc Feature(7)order(208..213,292..300,307..309,535..537,541..543,664..666)
Misc Feature(8)514..516
Misc Feature(9)952..954
Exon (1)1..57
Exon (2)58..166
Exon (3)167..277
Exon (4)278..1504
Translation

Target ORF information:

RefSeq Version NM_177987.2
Organism Homo sapiens(Human)
Definition Homo sapiens tubulin beta 8 class VIII (TUBB8), mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
NM_177987.2

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
ATGAGGGAGA TCGTGCTCAC GCAGATCGGG CAGTGCGGGA ATCAGATCGG CGCCAAGTTC 
TGGGAGGTGA TCTCTGATGA ACATGCCATC GACTCCGCTG GCACCTACCA CGGGGACAGC
CACCTGCAGC TGGAGCGCAT CAACGTGTAC TACAACGAGG CCAGCGGTGG CAGGTACGTG
CCCCGCGCTG TGCTCGTGGA TCTGGAGCCG GGCACCATGG ACTCTGTGCG CTCGGGGCCC
TTCGGGCAGG TCTTCAGGCC AGACAACTTC ATCTTCGGTC AGTGTGGGGC CGGAAACAAC
TGGGCCAAGG GACACTACAC CGAAGGCGCG GAGCTGATGG AGTCAGTGAT GGACGTTGTC
AGAAAGGAGG CTGAGAGCTG TGACTGCCTG CAGGGTTTCC AGCTGACCCA CTCCCTGGGT
GGGGGGACTG GGTCTGGGAT GGGTACCCTT CTGCTCAGTA AGATCCGGGA GGAGTACCCA
GACAGGATCA TAAACACATT CAGCATCCTG CCCTCGCCCA AGGTGTCGGA CACCGTGGTG
GAGCCCTACA ACGCCACCCT CTCAGTCCAC CAGCTCATAG AAAACGCAGA TGAGACCTTT
TGCATAGATA ACGAAGCTCT GTATGACATA TGTTCCAAGA CCCTAAAACT GCCCACACCC
ACCTATGGTG ACCTGAACCA CCTGGTGTCT GCTACCATGA GTGGGGTCAC CACGTGCCTG
CGCTTCCCGG GCCAGCTGAA TGCTGACCTG CGGAAGCTGG CCGTGAACAT GGTCCCGTTT
CCCCGGCTGC ATTTCTTCAT GCCCGGCTTT GCCCCACTGA CCAGCCGGGG CAGCCAGCAG
TACCGGGCCT TGACTGTGGC TGAGCTTACC CAGCAGATGT TTGATGCTAA GAACATGATG
GCTGCCTGTG ACCCCCGTCA CGGCCGCTAC CTAACGGCGG CTGCCATTTT CAGGGGTCGC
ATGCCCATGA GGGAGGTGGA TGAACAAATG TTCAACATTC AAGATAAGAA CAGCAGTTAC
TTTGCTGACT GGCTCCCCAA CAACGTAAAA ACAGCCGTCT GTGACATCCC ACCCCGGGGG
CTAAAAATGT CAGCCACCTT CATTGGGAAT AATACGGCCA TCCAGGAACT CTTCAAGCGT
GTCTCAGAGC AGTTTACAGC AATGTTCAGG CGCAAGGCCT TCCTCCACTG GTACACGGGC
GAGGGCATGG ATGAGATGGA ATTCACCGAG GCCGAGAGCA ACATGAACGA CCTGGTGTCT
GAATATCAGC AATATCAGGA TGCCACGGCC GAGGAGGAGG AGGATGAGGA GTATGCCGAG
GAGGAGGTGG CCTAG

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OHu79487
Clone ID Related Accession (Same CDS sequence) XM_011519459.2
Accession Version XM_011519459.2 Latest version! Documents for ORF clone product in dufault vector
Sequence Information ORF Nucleotide Sequence (Length: 1119bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ® Seamless cloning technology
Insert Structure linear
Update Date 2016-06-06
Organism Homo sapiens(Human)
Product tubulin beta-8 chain isoform X3
Comment MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000010.11) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 6, 2016 this sequence version replaced XM_011519459.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Homo sapiens Annotation Release 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
ATGGACTCTG TGCGCTCGGG GCCCTTCGGG CAGGTCTTCA GGCCAGACAA CTTCATCTTC 
GGTCAGTGTG GGGCCGGAAA CAACTGGGCC AAGGGACACT ACACCGAAGG CGCGGAGCTG
ATGGAGTCAG TGATGGACGT TGTCAGAAAG GAGGCTGAGA GCTGTGACTG CCTGCAGGGT
TTCCAGCTGA CCCACTCCCT GGGTGGGGGG ACTGGGTCTG GGATGGGTAC CCTTCTGCTC
AGTAAGATCC GGGAGGAGTA CCCAGACAGG ATCATAAACA CATTCAGCAT CCTGCCCTCG
CCCAAGGTGT CGGACACCGT GGTGGAGCCC TACAACGCCA CCCTCTCAGT CCACCAGCTC
ATAGAAAACG CAGATGAGAC CTTTTGCATA GATAACGAAG CTCTGTATGA CATATGTTCC
AAGACCCTAA AACTGCCCAC ACCCACCTAT GGTGACCTGA ACCACCTGGT GTCTGCTACC
ATGAGTGGGG TCACCACGTG CCTGCGCTTC CCGGGCCAGC TGAATGCTGA CCTGCGGAAG
CTGGCCGTGA ACATGGTCCC GTTTCCCCGG CTGCATTTCT TCATGCCCGG CTTTGCCCCA
CTGACCAGCC GGGGCAGCCA GCAGTACCGG GCCTTGACTG TGGCTGAGCT TACCCAGCAG
ATGTTTGATG CTAAGAACAT GATGGCTGCC TGTGACCCCC GTCACGGCCG CTACCTAACG
GCGGCTGCCA TTTTCAGGGG TCGCATGCCC ATGAGGGAGG TGGATGAACA AATGTTCAAC
ATTCAAGATA AGAACAGCAG TTACTTTGCT GACTGGCTCC CCAACAACGT AAAAACAGCC
GTCTGTGACA TCCCACCCCG GGGGCTAAAA ATGTCAGCCA CCTTCATTGG GAATAATACG
GCCATCCAGG AACTCTTCAA GCGTGTCTCA GAGCAGTTTA CAGCAATGTT CAGGCGCAAG
GCCTTCCTCC ACTGGTACAC GGGCGAGGGC ATGGATGAGA TGGAATTCAC CGAGGCCGAG
AGCAACATGA ACGACCTGGT GTCTGAATAT CAGCAATATC AGGATGCCAC GGCCGAGGAG
GAGGAGGATG AGGAGTATGC CGAGGAGGAG GTGGCCTAG

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq XP_011517761.1
CDS257..1375
Misc Feature(1)257..1321
Misc Feature(2)257..1318
Misc Feature(3)order(431..433,773..781,791..793,806..808,812..820,1004..1012,1019..1021,1079..1093)
Translation

Target ORF information:

RefSeq Version XM_011519459.2
Organism Homo sapiens(Human)
Definition Homo sapiens tubulin beta 8 class VIII (TUBB8), transcript variant X4, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
XM_011519459.2

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
ATGGACTCTG TGCGCTCGGG GCCCTTCGGG CAGGTCTTCA GGCCAGACAA CTTCATCTTC 
GGTCAGTGTG GGGCCGGAAA CAACTGGGCC AAGGGACACT ACACCGAAGG CGCGGAGCTG
ATGGAGTCAG TGATGGACGT TGTCAGAAAG GAGGCTGAGA GCTGTGACTG CCTGCAGGGT
TTCCAGCTGA CCCACTCCCT GGGTGGGGGG ACTGGGTCTG GGATGGGTAC CCTTCTGCTC
AGTAAGATCC GGGAGGAGTA CCCAGACAGG ATCATAAACA CATTCAGCAT CCTGCCCTCG
CCCAAGGTGT CGGACACCGT GGTGGAGCCC TACAACGCCA CCCTCTCAGT CCACCAGCTC
ATAGAAAACG CAGATGAGAC CTTTTGCATA GATAACGAAG CTCTGTATGA CATATGTTCC
AAGACCCTAA AACTGCCCAC ACCCACCTAT GGTGACCTGA ACCACCTGGT GTCTGCTACC
ATGAGTGGGG TCACCACGTG CCTGCGCTTC CCGGGCCAGC TGAATGCTGA CCTGCGGAAG
CTGGCCGTGA ACATGGTCCC GTTTCCCCGG CTGCATTTCT TCATGCCCGG CTTTGCCCCA
CTGACCAGCC GGGGCAGCCA GCAGTACCGG GCCTTGACTG TGGCTGAGCT TACCCAGCAG
ATGTTTGATG CTAAGAACAT GATGGCTGCC TGTGACCCCC GTCACGGCCG CTACCTAACG
GCGGCTGCCA TTTTCAGGGG TCGCATGCCC ATGAGGGAGG TGGATGAACA AATGTTCAAC
ATTCAAGATA AGAACAGCAG TTACTTTGCT GACTGGCTCC CCAACAACGT AAAAACAGCC
GTCTGTGACA TCCCACCCCG GGGGCTAAAA ATGTCAGCCA CCTTCATTGG GAATAATACG
GCCATCCAGG AACTCTTCAA GCGTGTCTCA GAGCAGTTTA CAGCAATGTT CAGGCGCAAG
GCCTTCCTCC ACTGGTACAC GGGCGAGGGC ATGGATGAGA TGGAATTCAC CGAGGCCGAG
AGCAACATGA ACGACCTGGT GTCTGAATAT CAGCAATATC AGGATGCCAC GGCCGAGGAG
GAGGAGGATG AGGAGTATGC CGAGGAGGAG GTGGCCTAG

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OHu79488
Clone ID Related Accession (Same CDS sequence) XM_011519460.2
Accession Version XM_011519460.2 Latest version! Documents for ORF clone product in dufault vector
Sequence Information ORF Nucleotide Sequence (Length: 876bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ® Seamless cloning technology
Insert Structure linear
Update Date 2016-06-06
Organism Homo sapiens(Human)
Product tubulin beta-8 chain isoform X2
Comment MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000010.11) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 6, 2016 this sequence version replaced XM_011519460.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Homo sapiens Annotation Release 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
ATGGTGGTGA CCACTGATGA CCGTATACCT GGCCGTCGAG TGACCGGCTG TGCTGTCTTA 
CAGGTGTCGG ACACCGTGGT GGAGCCCTAC AACGCCACCC TCTCAGTCCA CCAGCTCATA
GAAAACGCAG ATGAGACCTT TTGCATAGAT AACGAAGCTC TGTATGACAT ATGTTCCAAG
ACCCTAAAAC TGCCCACACC CACCTATGGT GACCTGAACC ACCTGGTGTC TGCTACCATG
AGTGGGGTCA CCACGTGCCT GCGCTTCCCG GGCCAGCTGA ATGCTGACCT GCGGAAGCTG
GCCGTGAACA TGGTCCCGTT TCCCCGGCTG CATTTCTTCA TGCCCGGCTT TGCCCCACTG
ACCAGCCGGG GCAGCCAGCA GTACCGGGCC TTGACTGTGG CTGAGCTTAC CCAGCAGATG
TTTGATGCTA AGAACATGAT GGCTGCCTGT GACCCCCGTC ACGGCCGCTA CCTAACGGCG
GCTGCCATTT TCAGGGGTCG CATGCCCATG AGGGAGGTGG ATGAACAAAT GTTCAACATT
CAAGATAAGA ACAGCAGTTA CTTTGCTGAC TGGCTCCCCA ACAACGTAAA AACAGCCGTC
TGTGACATCC CACCCCGGGG GCTAAAAATG TCAGCCACCT TCATTGGGAA TAATACGGCC
ATCCAGGAAC TCTTCAAGCG TGTCTCAGAG CAGTTTACAG CAATGTTCAG GCGCAAGGCC
TTCCTCCACT GGTACACGGG CGAGGGCATG GATGAGATGG AATTCACCGA GGCCGAGAGC
AACATGAACG ACCTGGTGTC TGAATATCAG CAATATCAGG ATGCCACGGC CGAGGAGGAG
GAGGATGAGG AGTATGCCGA GGAGGAGGTG GCCTAG

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq XP_011517762.1
CDS146..1021
Misc Feature(1)<173..964
Misc Feature(2)order(419..427,437..439,452..454,458..466,650..658,665..667,725..739)
Translation

Target ORF information:

RefSeq Version XM_011519460.2
Organism Homo sapiens(Human)
Definition Homo sapiens tubulin beta 8 class VIII (TUBB8), transcript variant X3, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
XM_011519460.2

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
ATGGTGGTGA CCACTGATGA CCGTATACCT GGCCGTCGAG TGACCGGCTG TGCTGTCTTA 
CAGGTGTCGG ACACCGTGGT GGAGCCCTAC AACGCCACCC TCTCAGTCCA CCAGCTCATA
GAAAACGCAG ATGAGACCTT TTGCATAGAT AACGAAGCTC TGTATGACAT ATGTTCCAAG
ACCCTAAAAC TGCCCACACC CACCTATGGT GACCTGAACC ACCTGGTGTC TGCTACCATG
AGTGGGGTCA CCACGTGCCT GCGCTTCCCG GGCCAGCTGA ATGCTGACCT GCGGAAGCTG
GCCGTGAACA TGGTCCCGTT TCCCCGGCTG CATTTCTTCA TGCCCGGCTT TGCCCCACTG
ACCAGCCGGG GCAGCCAGCA GTACCGGGCC TTGACTGTGG CTGAGCTTAC CCAGCAGATG
TTTGATGCTA AGAACATGAT GGCTGCCTGT GACCCCCGTC ACGGCCGCTA CCTAACGGCG
GCTGCCATTT TCAGGGGTCG CATGCCCATG AGGGAGGTGG ATGAACAAAT GTTCAACATT
CAAGATAAGA ACAGCAGTTA CTTTGCTGAC TGGCTCCCCA ACAACGTAAA AACAGCCGTC
TGTGACATCC CACCCCGGGG GCTAAAAATG TCAGCCACCT TCATTGGGAA TAATACGGCC
ATCCAGGAAC TCTTCAAGCG TGTCTCAGAG CAGTTTACAG CAATGTTCAG GCGCAAGGCC
TTCCTCCACT GGTACACGGG CGAGGGCATG GATGAGATGG AATTCACCGA GGCCGAGAGC
AACATGAACG ACCTGGTGTC TGAATATCAG CAATATCAGG ATGCCACGGC CGAGGAGGAG
GAGGATGAGG AGTATGCCGA GGAGGAGGTG GCCTAG

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OHu91381
Clone ID Related Accession (Same CDS sequence) XM_017016193.1 , XM_017016192.1
Accession Version XM_017016193.1 Latest version! Documents for ORF clone product in dufault vector
Sequence Information ORF Nucleotide Sequence (Length: 999bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ® Seamless cloning technology
Insert Structure linear
Update Date 2016-06-06
Organism Homo sapiens(Human)
Product tubulin beta-8 chain isoform X1
Comment MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000010.11) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Homo sapiens Annotation Release 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
ATGGAGTCAG TGATGGACGT TGTCAGAAAG GAGGCTGAGA GCTGTGACTG CCTGCAGGGT 
TTCCAGCTGA CCCACTCCCT GGGTGGGGGG ACTGGGTCTG GGATGGGTAC CCTTCTGCTC
AGTAAGATCC GGGAGGAGTA CCCAGACAGG ATCATAAACA CATTCAGCAT CCTGCCCTCG
CCCAAGGTGT CGGACACCGT GGTGGAGCCC TACAACGCCA CCCTCTCAGT CCACCAGCTC
ATAGAAAACG CAGATGAGAC CTTTTGCATA GATAACGAAG CTCTGTATGA CATATGTTCC
AAGACCCTAA AACTGCCCAC ACCCACCTAT GGTGACCTGA ACCACCTGGT GTCTGCTACC
ATGAGTGGGG TCACCACGTG CCTGCGCTTC CCGGGCCAGC TGAATGCTGA CCTGCGGAAG
CTGGCCGTGA ACATGGTCCC GTTTCCCCGG CTGCATTTCT TCATGCCCGG CTTTGCCCCA
CTGACCAGCC GGGGCAGCCA GCAGTACCGG GCCTTGACTG TGGCTGAGCT TACCCAGCAG
ATGTTTGATG CTAAGAACAT GATGGCTGCC TGTGACCCCC GTCACGGCCG CTACCTAACG
GCGGCTGCCA TTTTCAGGGG TCGCATGCCC ATGAGGGAGG TGGATGAACA AATGTTCAAC
ATTCAAGATA AGAACAGCAG TTACTTTGCT GACTGGCTCC CCAACAACGT AAAAACAGCC
GTCTGTGACA TCCCACCCCG GGGGCTAAAA ATGTCAGCCA CCTTCATTGG GAATAATACG
GCCATCCAGG AACTCTTCAA GCGTGTCTCA GAGCAGTTTA CAGCAATGTT CAGGCGCAAG
GCCTTCCTCC ACTGGTACAC GGGCGAGGGC ATGGATGAGA TGGAATTCAC CGAGGCCGAG
AGCAACATGA ACGACCTGGT GTCTGAATAT CAGCAATATC AGGATGCCAC GGCCGAGGAG
GAGGAGGATG AGGAGTATGC CGAGGAGGAG GTGGCCTAG

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq XP_016871682.1
CDS94..1092
Translation

Target ORF information:

RefSeq Version XM_017016193.1
Organism Homo sapiens(Human)
Definition Homo sapiens tubulin beta 8 class VIII (TUBB8), transcript variant X2, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
XM_017016193.1

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
ATGGAGTCAG TGATGGACGT TGTCAGAAAG GAGGCTGAGA GCTGTGACTG CCTGCAGGGT 
TTCCAGCTGA CCCACTCCCT GGGTGGGGGG ACTGGGTCTG GGATGGGTAC CCTTCTGCTC
AGTAAGATCC GGGAGGAGTA CCCAGACAGG ATCATAAACA CATTCAGCAT CCTGCCCTCG
CCCAAGGTGT CGGACACCGT GGTGGAGCCC TACAACGCCA CCCTCTCAGT CCACCAGCTC
ATAGAAAACG CAGATGAGAC CTTTTGCATA GATAACGAAG CTCTGTATGA CATATGTTCC
AAGACCCTAA AACTGCCCAC ACCCACCTAT GGTGACCTGA ACCACCTGGT GTCTGCTACC
ATGAGTGGGG TCACCACGTG CCTGCGCTTC CCGGGCCAGC TGAATGCTGA CCTGCGGAAG
CTGGCCGTGA ACATGGTCCC GTTTCCCCGG CTGCATTTCT TCATGCCCGG CTTTGCCCCA
CTGACCAGCC GGGGCAGCCA GCAGTACCGG GCCTTGACTG TGGCTGAGCT TACCCAGCAG
ATGTTTGATG CTAAGAACAT GATGGCTGCC TGTGACCCCC GTCACGGCCG CTACCTAACG
GCGGCTGCCA TTTTCAGGGG TCGCATGCCC ATGAGGGAGG TGGATGAACA AATGTTCAAC
ATTCAAGATA AGAACAGCAG TTACTTTGCT GACTGGCTCC CCAACAACGT AAAAACAGCC
GTCTGTGACA TCCCACCCCG GGGGCTAAAA ATGTCAGCCA CCTTCATTGG GAATAATACG
GCCATCCAGG AACTCTTCAA GCGTGTCTCA GAGCAGTTTA CAGCAATGTT CAGGCGCAAG
GCCTTCCTCC ACTGGTACAC GGGCGAGGGC ATGGATGAGA TGGAATTCAC CGAGGCCGAG
AGCAACATGA ACGACCTGGT GTCTGAATAT CAGCAATATC AGGATGCCAC GGCCGAGGAG
GAGGAGGATG AGGAGTATGC CGAGGAGGAG GTGGCCTAG

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OHu91381
Clone ID Related Accession (Same CDS sequence) XM_017016193.1 , XM_017016192.1
Accession Version XM_017016192.1 Latest version! Documents for ORF clone product in dufault vector
Sequence Information ORF Nucleotide Sequence (Length: 999bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ® Seamless cloning technology
Insert Structure linear
Update Date 2016-06-06
Organism Homo sapiens(Human)
Product tubulin beta-8 chain isoform X1
Comment MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000010.11) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Homo sapiens Annotation Release 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
ATGGAGTCAG TGATGGACGT TGTCAGAAAG GAGGCTGAGA GCTGTGACTG CCTGCAGGGT 
TTCCAGCTGA CCCACTCCCT GGGTGGGGGG ACTGGGTCTG GGATGGGTAC CCTTCTGCTC
AGTAAGATCC GGGAGGAGTA CCCAGACAGG ATCATAAACA CATTCAGCAT CCTGCCCTCG
CCCAAGGTGT CGGACACCGT GGTGGAGCCC TACAACGCCA CCCTCTCAGT CCACCAGCTC
ATAGAAAACG CAGATGAGAC CTTTTGCATA GATAACGAAG CTCTGTATGA CATATGTTCC
AAGACCCTAA AACTGCCCAC ACCCACCTAT GGTGACCTGA ACCACCTGGT GTCTGCTACC
ATGAGTGGGG TCACCACGTG CCTGCGCTTC CCGGGCCAGC TGAATGCTGA CCTGCGGAAG
CTGGCCGTGA ACATGGTCCC GTTTCCCCGG CTGCATTTCT TCATGCCCGG CTTTGCCCCA
CTGACCAGCC GGGGCAGCCA GCAGTACCGG GCCTTGACTG TGGCTGAGCT TACCCAGCAG
ATGTTTGATG CTAAGAACAT GATGGCTGCC TGTGACCCCC GTCACGGCCG CTACCTAACG
GCGGCTGCCA TTTTCAGGGG TCGCATGCCC ATGAGGGAGG TGGATGAACA AATGTTCAAC
ATTCAAGATA AGAACAGCAG TTACTTTGCT GACTGGCTCC CCAACAACGT AAAAACAGCC
GTCTGTGACA TCCCACCCCG GGGGCTAAAA ATGTCAGCCA CCTTCATTGG GAATAATACG
GCCATCCAGG AACTCTTCAA GCGTGTCTCA GAGCAGTTTA CAGCAATGTT CAGGCGCAAG
GCCTTCCTCC ACTGGTACAC GGGCGAGGGC ATGGATGAGA TGGAATTCAC CGAGGCCGAG
AGCAACATGA ACGACCTGGT GTCTGAATAT CAGCAATATC AGGATGCCAC GGCCGAGGAG
GAGGAGGATG AGGAGTATGC CGAGGAGGAG GTGGCCTAG

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq XP_016871681.1
CDS274..1272
Translation

Target ORF information:

RefSeq Version XM_017016192.1
Organism Homo sapiens(Human)
Definition Homo sapiens tubulin beta 8 class VIII (TUBB8), transcript variant X1, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
XM_017016192.1

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
ATGGAGTCAG TGATGGACGT TGTCAGAAAG GAGGCTGAGA GCTGTGACTG CCTGCAGGGT 
TTCCAGCTGA CCCACTCCCT GGGTGGGGGG ACTGGGTCTG GGATGGGTAC CCTTCTGCTC
AGTAAGATCC GGGAGGAGTA CCCAGACAGG ATCATAAACA CATTCAGCAT CCTGCCCTCG
CCCAAGGTGT CGGACACCGT GGTGGAGCCC TACAACGCCA CCCTCTCAGT CCACCAGCTC
ATAGAAAACG CAGATGAGAC CTTTTGCATA GATAACGAAG CTCTGTATGA CATATGTTCC
AAGACCCTAA AACTGCCCAC ACCCACCTAT GGTGACCTGA ACCACCTGGT GTCTGCTACC
ATGAGTGGGG TCACCACGTG CCTGCGCTTC CCGGGCCAGC TGAATGCTGA CCTGCGGAAG
CTGGCCGTGA ACATGGTCCC GTTTCCCCGG CTGCATTTCT TCATGCCCGG CTTTGCCCCA
CTGACCAGCC GGGGCAGCCA GCAGTACCGG GCCTTGACTG TGGCTGAGCT TACCCAGCAG
ATGTTTGATG CTAAGAACAT GATGGCTGCC TGTGACCCCC GTCACGGCCG CTACCTAACG
GCGGCTGCCA TTTTCAGGGG TCGCATGCCC ATGAGGGAGG TGGATGAACA AATGTTCAAC
ATTCAAGATA AGAACAGCAG TTACTTTGCT GACTGGCTCC CCAACAACGT AAAAACAGCC
GTCTGTGACA TCCCACCCCG GGGGCTAAAA ATGTCAGCCA CCTTCATTGG GAATAATACG
GCCATCCAGG AACTCTTCAA GCGTGTCTCA GAGCAGTTTA CAGCAATGTT CAGGCGCAAG
GCCTTCCTCC ACTGGTACAC GGGCGAGGGC ATGGATGAGA TGGAATTCAC CGAGGCCGAG
AGCAACATGA ACGACCTGGT GTCTGAATAT CAGCAATATC AGGATGCCAC GGCCGAGGAG
GAGGAGGATG AGGAGTATGC CGAGGAGGAG GTGGCCTAG

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

book

Mutations in TUBB8 and Human Oocyte Meiotic Arrest.
The New England journal of medicine374(3)223-32(2016 Jan)
Feng R,Sang Q,Kuang Y,Sun X,Yan Z,Zhang S,Shi J,Tian G,Luchniak A,Fukuda Y,Li B,Yu M,Chen J,Xu Y,Guo L,Qu R,Wang X,Sun Z,Liu M,Shi H,Wang H,Feng Y,Shao R,Chai R,Li Q,Xing Q,Zhang R,Nogales E,Jin L,He L,Gupta ML Jr,Cowan NJ,Wang L


book

A cascade of complex subtelomeric duplications during the evolution of the hominoid and Old World monkey genomes.
American journal of human genetics70(1)269-78(2002 Jan)
van Geel M,Eichler EE,Beck AF,Shan Z,Haaf T,van der Maarel SM,Frants RR,de Jong PJ


book

Identification of a novel beta-tubulin subfamily with one member (TUBB4Q) located near the telomere of chromosome region 4q35.
Cytogenetics and cell genetics88(3-4)316-21(2000)
van Geel M,van Deutekom JC,van Staalduinen A,Lemmers RJ,Dickson MC,Hofker MH,Padberg GW,Hewitt JE,de Jong PJ,Frants RR


 
*
*
*
*