Gene Symbol | LAMTOR4 |
Entrez Gene ID | 389541 |
Full Name | late endosomal/lysosomal adaptor, MAPK and MTOR activator 4 |
Synonyms | C7orf59 |
General protein information |
|
Gene Type | protein-coding |
Organism | Homo sapiens(human) |
Genome |
ORF » Species Summary » Homo sapiens » LAMTOR4 cDNA ORF clone
gRNAs
Gene Symbol | LAMTOR4 |
Entrez Gene ID | 389541 |
Full Name | late endosomal/lysosomal adaptor, MAPK and MTOR activator 4 |
Synonyms | C7orf59 |
General protein information |
|
Gene Type | protein-coding |
Organism | Homo sapiens(human) |
Genome |
mRNA | Protein | Name |
---|---|---|
NM_001008395.2 | NP_001008396.1 | ragulator complex protein LAMTOR4 |
NM_001008395.3 | NP_001008396.1 | ragulator complex protein LAMTOR4 isoform 1 |
XM_024446760.1 | XP_024302528.1 | ragulator complex protein LAMTOR4 isoform X1 |
NM_001318237.1 | NP_001305166.1 | ragulator complex protein LAMTOR4 isoform 3 |
XM_017012199.1 | XP_016867688.1 | ragulator complex protein LAMTOR4 isoform X2 |
XM_017012198.1 | XP_016867687.1 | ragulator complex protein LAMTOR4 isoform X1 |
NM_001318236.2 | NP_001305165.1 | ragulator complex protein LAMTOR4 isoform 2 |
NM_001318237.2 | NP_001305166.1 | ragulator complex protein LAMTOR4 isoform 3 |
NM_001318236.1 | NP_001305165.1 | ragulator complex protein LAMTOR4 isoform 2 |
XM_024446761.1 | XP_024302529.1 | ragulator complex protein LAMTOR4 isoform X2 |
NM_001008395.4 | NP_001008396.1 | ragulator complex protein LAMTOR4 isoform 1 |
SLC38A9 is a component of the lysosomal amino acid sensing machinery that controls mTORC1.
Rebsamen M, Pochini L, Stasyk T, de Ara?jo ME, Galluccio M, Kandasamy RK, Snijder B, Fauster A, Rudashevskaya EL, Bruckner M, Scorzoni S, Filipek PA, Huber KV, Bigenzahn JW, Heinz LX, Kraft C, Bennett KL, Indiveri C, Huber LA, Superti-Furga G
Nature519(7544)477-81(2015 Mar)
Metabolism. Lysosomal amino acid transporter SLC38A9 signals arginine sufficiency to mTORC1.
Wang S, Tsun ZY, Wolfson RL, Shen K, Wyant GA, Plovanich ME, Yuan ED, Jones TD, Chantranupong L, Comb W, Wang T, Bar-Peled L, Zoncu R, Straub C, Kim C, Park J, Sabatini BL, Sabatini DM
Science (New York, N.Y.)347(6218)188-94(2015 Jan)
A human skeletal muscle interactome centered on proteins involved in muscular dystrophies: LGMD interactome.
Blandin G, Marchand S, Charton K, Dani?le N, Gicquel E, Boucheteil JB, Bentaib A, Barrault L, Stockholm D, Bartoli M, Richard I
Skeletal muscle3(1)3(2013 Feb)
Ragulator is a GEF for the rag GTPases that signal amino acid levels to mTORC1.
Bar-Peled L, Schweitzer LD, Zoncu R, Sabatini DM
Cell150(6)1196-208(2012 Sep)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
Study identified HBXIP and C7orf59 as two additional Ragulator components that are required for mTORC1 activation by amino acids.
Title: Ragulator is a GEF for the rag GTPases that signal amino acid levels to mTORC1.
The following LAMTOR4 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the LAMTOR4 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
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CloneID | OHu11251![]() |
|
Clone ID Related Accession (Same CDS sequence) | NM_001008395.2 , NM_001008395.3 , XM_024446760.1 , XM_017012198.1 , NM_001008395.4 | |
Accession Version | NM_001008395.2 | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 300bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | ![]() |
Clone information | Clone Map | ![]() |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2015-03-14 | |
Organism | Homo sapiens(Human) | |
Product | ragulator complex protein LAMTOR4 | |
Comment |
1 | ATGACTTCTG CGCTGACCCA GGGGCTGGAG CGAATCCCAG ACCAGCTCGG CTACCTGGTA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_001008396.1 |
Translation |
Target ORF information:
Target ORF information:
|
![]() |
1 | ATGACTTCTG CGCTGACCCA GGGGCTGGAG CGAATCCCAG ACCAGCTCGG CTACCTGGTA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OHu11251![]() |
|
Clone ID Related Accession (Same CDS sequence) | NM_001008395.2 , NM_001008395.3 , XM_024446760.1 , XM_017012198.1 , NM_001008395.4 | |
Accession Version | NM_001008395.3 | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 300bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | ![]() |
Clone information | Clone Map | ![]() |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-02-24 | |
Organism | Homo sapiens(human) | |
Product | ragulator complex protein LAMTOR4 isoform 1 | |
Comment | Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from CU450474.1, BI598677.1 and AA772120.1. On Dec 31, 2015 this sequence version replaced NM_001008395.2. Transcript Variant: This variant (1) encodes the longest isoform (1). ##Evidence-Data-START## Transcript exon combination :: SRR1163655.194234.1, SRR1163657.319544.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end. |
1 | ATGACTTCTG CGCTGACCCA GGGGCTGGAG CGAATCCCAG ACCAGCTCGG CTACCTGGTA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_001008396.1 |
CDS | 75..374 |
Translation |
Target ORF information:
Target ORF information:
|
![]() |
1 | ATGACTTCTG CGCTGACCCA GGGGCTGGAG CGAATCCCAG ACCAGCTCGG CTACCTGGTA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OHu11251![]() |
|
Clone ID Related Accession (Same CDS sequence) | NM_001008395.2 , NM_001008395.3 , XM_024446760.1 , XM_017012198.1 , NM_001008395.4 | |
Accession Version | NM_001008395.4 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 300bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | ![]() |
Clone information | Clone Map | ![]() |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2020-01-03 | |
Organism | Homo sapiens(human) | |
Product | ragulator complex protein LAMTOR4 isoform 1 | |
Comment | Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from CU450474.1 and BI598677.1. On Jun 2, 2019 this sequence version replaced NM_001008395.3. Transcript Variant: This variant (1) encodes the longest isoform (1). ##Evidence-Data-START## Transcript exon combination :: BC063401.1, BI754529.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## RefSeq Select criteria :: based on conservation, expression, longest protein ##RefSeq-Attributes-END## COMPLETENESS: complete on the 3' end. |
1 | ATGACTTCTG CGCTGACCCA GGGGCTGGAG CGAATCCCAG ACCAGCTCGG CTACCTGGTA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_001008396.1 |
CDS | 56..355 |
Translation |
Target ORF information:
Target ORF information:
|
![]() |
1 | ATGACTTCTG CGCTGACCCA GGGGCTGGAG CGAATCCCAG ACCAGCTCGG CTACCTGGTA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OHu11251![]() |
|
Clone ID Related Accession (Same CDS sequence) | NM_001008395.2 , NM_001008395.3 , XM_024446760.1 , XM_017012198.1 , NM_001008395.4 | |
Accession Version | XM_024446760.1 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 300bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | ![]() |
Clone information | Clone Map | ![]() |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-12-05 | |
Organism | Homo sapiens(human) | |
Product | ragulator complex protein LAMTOR4 isoform X1 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000007.14) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGACTTCTG CGCTGACCCA GGGGCTGGAG CGAATCCCAG ACCAGCTCGG CTACCTGGTA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_024302528.1 |
CDS | 388..687 |
Translation |
Target ORF information:
Target ORF information:
|
![]() |
1 | ATGACTTCTG CGCTGACCCA GGGGCTGGAG CGAATCCCAG ACCAGCTCGG CTACCTGGTA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OHu11251![]() |
|
Clone ID Related Accession (Same CDS sequence) | NM_001008395.2 , NM_001008395.3 , XM_024446760.1 , XM_017012198.1 , NM_001008395.4 | |
Accession Version | XM_017012198.1 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 300bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | ![]() |
Clone information | Clone Map | ![]() |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2016-06-05 | |
Organism | Homo sapiens(human) | |
Product | ragulator complex protein LAMTOR4 isoform X1 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000007.14) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Homo sapiens Annotation Release 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGACTTCTG CGCTGACCCA GGGGCTGGAG CGAATCCCAG ACCAGCTCGG CTACCTGGTA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_016867687.1 |
CDS | 462..761 |
Translation |
Target ORF information:
Target ORF information:
|
![]() |
1 | ATGACTTCTG CGCTGACCCA GGGGCTGGAG CGAATCCCAG ACCAGCTCGG CTACCTGGTA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OHu101816 | |
Clone ID Related Accession (Same CDS sequence) | NM_001318237.1 , NM_001318237.2 | |
Accession Version | NM_001318237.1 | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 219bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | ![]() |
Clone information | Clone Map | ![]() |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2018-06-30 | |
Organism | Homo sapiens(human) | |
Product | ragulator complex protein LAMTOR4 isoform 3 | |
Comment | Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from CU450474.1, BI771662.1 and AA772120.1. Transcript Variant: This variant (3) lacks an in-frame exon in the 5' coding region compared to variant 1. The encoded isoform (3) is shorter than isoform 1. ##Evidence-Data-START## Transcript exon combination :: BI771662.1, BY796807.2 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1966682, SAMEA1968832 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end. |
1 | ATGTCATCTG GGGACCTGGA GAATGATGAG CAGGCAGCCA GTGCCATCTC TGAGCTGGTC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_001305166.1 |
CDS | 75..293 |
Translation |
Target ORF information:
Target ORF information:
|
![]() |
1 | ATGTCATCTG GGGACCTGGA GAATGATGAG CAGGCAGCCA GTGCCATCTC TGAGCTGGTC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OHu101816 | |
Clone ID Related Accession (Same CDS sequence) | NM_001318237.1 , NM_001318237.2 | |
Accession Version | NM_001318237.2 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 219bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | ![]() |
Clone information | Clone Map | ![]() |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-09-28 | |
Organism | Homo sapiens(human) | |
Product | ragulator complex protein LAMTOR4 isoform 3 | |
Comment | Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from CU450474.1 and BI771662.1. On Jun 2, 2019 this sequence version replaced NM_001318237.1. Transcript Variant: This variant (3) lacks an in-frame exon in the 5' coding region compared to variant 1. The encoded isoform (3) is shorter than isoform 1. ##Evidence-Data-START## Transcript exon combination :: BI771662.1, BY796807.2 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1966682, SAMEA1968832 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end. |
1 | ATGTCATCTG GGGACCTGGA GAATGATGAG CAGGCAGCCA GTGCCATCTC TGAGCTGGTC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_001305166.1 |
CDS | 56..274 |
Translation |
Target ORF information:
Target ORF information:
|
![]() |
1 | ATGTCATCTG GGGACCTGGA GAATGATGAG CAGGCAGCCA GTGCCATCTC TGAGCTGGTC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OHu97247 | |
Clone ID Related Accession (Same CDS sequence) | XM_017012199.1 , NM_001318236.2 , NM_001318236.1 , XM_024446761.1 | |
Accession Version | NM_001318236.2 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 249bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | ![]() |
Clone information | Clone Map | ![]() |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2020-01-04 | |
Organism | Homo sapiens(human) | |
Product | ragulator complex protein LAMTOR4 isoform 2 | |
Comment | Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from CU450474.1, BG706819.1 and AA772120.1. On Jun 2, 2019 this sequence version replaced NM_001318236.1. Transcript Variant: This variant (2) uses an alternate splice site in the 3' coding region, which introduces a frameshift compared to variant 1. The encoded isoform (2) has a shorter and distinct C-terminus, compared to isoform 1. ##Evidence-Data-START## Transcript exon combination :: BU602608.1, DRR138524.848061.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end. |
1 | ATGACTTCTG CGCTGACCCA GGGGCTGGAG CGAATCCCAG ACCAGCTCGG CTACCTGGTA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_001305165.1 |
CDS | 56..304 |
Translation |
Target ORF information:
Target ORF information:
|
![]() |
1 | ATGACTTCTG CGCTGACCCA GGGGCTGGAG CGAATCCCAG ACCAGCTCGG CTACCTGGTA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OHu97247 | |
Clone ID Related Accession (Same CDS sequence) | XM_017012199.1 , NM_001318236.2 , NM_001318236.1 , XM_024446761.1 | |
Accession Version | NM_001318236.1 | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 249bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | ![]() |
Clone information | Clone Map | ![]() |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-02-24 | |
Organism | Homo sapiens(human) | |
Product | ragulator complex protein LAMTOR4 isoform 2 | |
Comment | Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from CU450474.1, BG706819.1 and AA772120.1. Transcript Variant: This variant (2) uses an alternate splice site in the 3' coding region, which introduces a frameshift compared to variant 1. The encoded isoform (2) has a shorter and distinct C-terminus, compared to isoform 1. ##Evidence-Data-START## Transcript exon combination :: BU602608.1, DB562023.2 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end. |
1 | ATGACTTCTG CGCTGACCCA GGGGCTGGAG CGAATCCCAG ACCAGCTCGG CTACCTGGTA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_001305165.1 |
CDS | 75..323 |
Translation |
Target ORF information:
Target ORF information:
|
![]() |
1 | ATGACTTCTG CGCTGACCCA GGGGCTGGAG CGAATCCCAG ACCAGCTCGG CTACCTGGTA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OHu97247 | |
Clone ID Related Accession (Same CDS sequence) | XM_017012199.1 , NM_001318236.2 , NM_001318236.1 , XM_024446761.1 | |
Accession Version | XM_017012199.1 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 249bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | ![]() |
Clone information | Clone Map | ![]() |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2016-06-05 | |
Organism | Homo sapiens(human) | |
Product | ragulator complex protein LAMTOR4 isoform X2 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000007.14) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Homo sapiens Annotation Release 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGACTTCTG CGCTGACCCA GGGGCTGGAG CGAATCCCAG ACCAGCTCGG CTACCTGGTA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_016867688.1 |
CDS | 462..710 |
Translation |
Target ORF information:
Target ORF information:
|
![]() |
1 | ATGACTTCTG CGCTGACCCA GGGGCTGGAG CGAATCCCAG ACCAGCTCGG CTACCTGGTA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OHu97247 | |
Clone ID Related Accession (Same CDS sequence) | XM_017012199.1 , NM_001318236.2 , NM_001318236.1 , XM_024446761.1 | |
Accession Version | XM_024446761.1 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 249bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | ![]() |
Clone information | Clone Map | ![]() |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-12-05 | |
Organism | Homo sapiens(human) | |
Product | ragulator complex protein LAMTOR4 isoform X2 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000007.14) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGACTTCTG CGCTGACCCA GGGGCTGGAG CGAATCCCAG ACCAGCTCGG CTACCTGGTA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_024302529.1 |
CDS | 388..636 |
Translation |
Target ORF information:
Target ORF information:
|
![]() |
1 | ATGACTTCTG CGCTGACCCA GGGGCTGGAG CGAATCCCAG ACCAGCTCGG CTACCTGGTA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
SLC38A9 is a component of the lysosomal amino acid sensing machinery that controls mTORC1. |
Metabolism. Lysosomal amino acid transporter SLC38A9 signals arginine sufficiency to mTORC1. |
A human skeletal muscle interactome centered on proteins involved in muscular dystrophies: LGMD interactome. |
Ragulator is a GEF for the rag GTPases that signal amino acid levels to mTORC1. |