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MAG cDNA ORF clone, Homo sapiens (human)

Gene Symbol MAG
Entrez Gene ID 4099
Full Name myelin associated glycoprotein
Synonyms GMA, S-MAG, SIGLEC-4A, SIGLEC4A
General protein information
Preferred Names
myelin-associated glycoprotein
Names
myelin-associated glycoprotein
sialic acid binding Ig-like lectin 4A
sialic acid-binding immunoglobulin-like lectin 4A
Gene Type protein-coding
Organism Homo sapiens (human)
Genome

19

19q13.1

Summary The protein encoded by this gene is a type I membrane protein and member of the immunoglobulin superfamily. It is thought to be involved in the process of myelination. It is a lectin that binds to sialylated glycoconjugates and mediates certain myelin-neuron cell-cell interactions. Three alternatively spliced transcripts encoding different isoforms have been described for this gene. [provided by RefSeq, Nov 2010]. lac of sum
Disorder MIM:

159460


mRNA and Protein(s)

mRNA Protein Name
NM_080600 NP_542167 myelin-associated glycoprotein isoform b precursor
NM_002361 NP_002352 myelin-associated glycoprotein isoform a precursor
NM_001199216 NP_001186145 myelin-associated glycoprotein isoform c



Homo sapiens (human) MAG NP_002352.1
Macaca mulatta (Rhesus monkey) MAG XP_001111459.2
Canis lupus familiaris (dog) MAG XP_005616772.1
Bos taurus (cattle) MAG NP_001035660.2
Mus musculus (house mouse) Mag NP_034888.1
Rattus norvegicus (Norway rat) Mag NP_058886.1
Danio rerio (zebrafish) mag NP_001007063.1
Xenopus (Silurana) tropicalis (western clawed frog) mag XP_002943135.1


GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following MAG gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the MAG cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID RefSeq Accession Definition **Vector *Turnaround time Price Select
OHu19652 NM_080600 Homo sapiens myelin associated glycoprotein (MAG), transcript variant 2, mRNA. pcDNA3.1+/C-(K)DYK or customized vector 7-9 $265.30
$379.00
OHu13785
NM_002361 Homo sapiens myelin associated glycoprotein (MAG), transcript variant 1, mRNA. pcDNA3.1+/C-(K)DYK or customized vector
in pcDNA3.1+/C-(K)DYK
$204.50-$286.30
$409.00
OHu13781
NM_001199216 Homo sapiens myelin associated glycoprotein (MAG), transcript variant 3, mRNA. pcDNA3.1+/C-(K)DYK or customized vector
in pcDNA3.1+/C-(K)DYK
$219.50-$307.30
$439.00
Next-day Shipping ORF Clones ( in default vector with tag)
1 Clone 30% OFF
2-4 Clone 40% OFF
5 or more Clone 50% OFF
All Other ORF Clones
30% OFF

*Business Day

** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.


CloneID OHu19652
Clone ID Related Accession (Same CDS sequence) NM_080600
Accession Version NM_080600.2 Documents for ORF clone product in dufault vector
Sequence Information ORF Nucleotide Sequence (Length: 1749bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ® Seamless cloning technology
Structure linear
Update Date 15-MAR-2015
Organism Homo sapiens (human)
Product myelin-associated glycoprotein isoform b precursor
Comment REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from DC331168.1 and BC093045.1. This sequence is a reference standard in the RefSeqGene project. On or before Aug 31, 2013 this sequence version replaced gi:530416606, gi:18104956. Transcript Variant: This variant (2) is a full-length transcript with the stop codon contained in exon 11. It encodes an isoform (b) that is 44 aa shorter and contains a different carboxy terminus when compared to isoform a. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC093045.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2145743, SAMEA2154665 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: full length.

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
1501
1561
1621
1681
1741
ATGATATTCC TCACGGCACT GCCTCTGTTC TGGATTATGA TTTCAGCCTC CCGAGGGGGT 
CACTGGGGTG CCTGGATGCC CTCGTCCATC TCGGCCTTCG AAGGCACGTG CGTCTCCATC
CCCTGCCGCT TTGACTTCCC GGATGAGCTG CGGCCCGCTG TGGTGCATGG TGTCTGGTAC
TTCAATAGCC CCTACCCCAA GAACTACCCC CCGGTGGTCT TCAAGTCGCG CACCCAAGTA
GTCCACGAGA GCTTCCAGGG CCGCAGCCGC CTCCTGGGGG ACCTGGGCCT GCGAAACTGC
ACCCTCCTGC TCAGCAACGT CAGCCCCGAG CTGGGCGGGA AGTACTACTT CCGTGGGGAC
CTGGGCGGCT ACAACCAGTA CACCTTCTCA GAGCACAGCG TCCTGGATAT CGTCAACACC
CCCAACATCG TGGTGCCCCC AGAGGTGGTG GCAGGCACGG AGGTGGAGGT CAGCTGCATG
GTGCCGGACA ACTGCCCAGA GCTGCGCCCT GAGCTGAGCT GGCTGGGCCA CGAGGGGCTG
GGGGAGCCCG CTGTGCTGGG CCGGCTGCGG GAGGACGAGG GCACCTGGGT GCAGGTGTCA
CTGCTGCACT TCGTGCCCAC GAGGGAGGCC AACGGCCACA GGCTGGGCTG CCAGGCCTCC
TTCCCCAACA CCACCCTGCA GTTCGAGGGC TACGCCAGCA TGGACGTCAA GTACCCCCCG
GTGATTGTGG AGATGAACTC CTCGGTGGAG GCCATCGAGG GCTCCCACGT GAGCCTGCTC
TGTGGGGCTG ACAGCAACCC CCCGCCGCTG CTGACCTGGA TGCGGGACGG GACAGTCCTC
CGGGAGGCGG TGGCCGAGAG CCTGCTCCTG GAGCTGGAGG AGGTGACCCC CGCCGAAGAC
GGCGTCTATG CCTGCCTGGC CGAGAATGCC TATGGCCAGG ACAACCGCAC CGTGGGGCTC
AGTGTCATGT ATGCACCCTG GAAGCCAACA GTGAACGGGA CAATGGTGGC CGTAGAGGGG
GAGACGGTCT CTATCTTGTG CTCCACACAG AGCAACCCGG ACCCTATTCT CACCATCTTC
AAGGAGAAGC AGATCCTGTC CACGGTCATC TACGAGAGCG AGCTGCAGCT GGAGCTGCCG
GCCGTGTCAC CCGAGGATGA TGGAGAGTAC TGGTGTGTGG CTGAGAACCA GTATGGCCAG
AGGGCCACCG CCTTCAACCT GTCTGTGGAG TTCGCCCCTG TGCTCCTCCT GGAGTCCCAC
TGCGCGGCAG CCCGAGACAC GGTGCAGTGC CTGTGCGTGG TGAAGTCCAA CCCGGAGCCG
TCCGTGGCCT TTGAGCTGCC ATCGCGCAAT GTGACCGTGA ACGAGAGCGA GCGGGAGTTC
GTGTACTCGG AGCGCAGCGG CCTCGTGCTC ACCAGCATCC TCACGCTGCG GGGGCAGGCC
CAGGCCCCGC CCCGCGTCAT CTGCACCGCG AGGAACCTCT ATGGCGCCAA GAGCCTGGAG
CTGCCCTTCC AGGGAGCCCA TCGACTGATG TGGGCCAAGA TCGGGCCTGT GGGCGCCGTG
GTCGCCTTTG CCATCCTGAT TGCCATCGTC TGCTACATTA CCCAGACACG CAGGAAAAAG
AACGTGACAG AGAGCCCCAG CTTCTCGGCA GGGGACAACC CTCCCGTCCT GTTCAGCAGC
GACTTCCGCA TCTCTGGGGC ACCAGAGAAG TACGAGTCCA AAGAGGTTTC TACCCTGGAA
TCTCACTGA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq NP_542167.1
CDS199..1947
Misc Feature(1)262..615(+)
Misc Feature(2)277..>546(+)
Misc Feature(3)493..495(+)
Misc Feature(4)514..516(+)
Misc Feature(5)550..582(+)
Misc Feature(6)619..864(+)
Misc Feature(7)865..867(+)
Misc Feature(8)916..1164(+)
Misc Feature(9)934..936(+)
Misc Feature(10)958..1164(+)
Misc Feature(11)1141..1143(+)
Misc Feature(12)1192..1194(+)
Misc Feature(13)1195..1425(+)
Misc Feature(14)1207..1398(+)
Misc Feature(15)1414..1416(+)
Misc Feature(16)1546..1548(+)
Misc Feature(17)1558..1560(+)
Misc Feature(18)1747..1806(+)
Exon (1)1..119
Gene:MAG
Gene Synonym:
Exon (2)120..175
Gene:MAG
Gene Synonym:
Exon (3)176..244
Gene:MAG
Gene Synonym:
Exon (4)245..613
Gene:MAG
Gene Synonym:
Exon (5)614..910
Gene:MAG
Gene Synonym:
Exon (6)911..1168
Gene:MAG
Gene Synonym:
Exon (7)1169..1429
Gene:MAG
Gene Synonym:
Exon (8)1430..1717
Gene:MAG
Gene Synonym:
Exon (9)1718..1814
Gene:MAG
Gene Synonym:
Exon (10)1815..1914
Gene:MAG
Gene Synonym:
Exon (11)1915..1959
Gene:MAG
Gene Synonym:
Exon (12)1960..2477
Gene:MAG
Gene Synonym:
Translation

Target ORF information:

RefSeq Version NM_080600
Organism Homo sapiens (human)
Definition Homo sapiens myelin associated glycoprotein (MAG), transcript variant 2, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
NM_080600

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
1501
1561
1621
1681
1741
ATGATATTCC TCACGGCACT GCCTCTGTTC TGGATTATGA TTTCAGCCTC CCGAGGGGGT 
CACTGGGGTG CCTGGATGCC CTCGTCCATC TCGGCCTTCG AAGGCACGTG CGTCTCCATC
CCCTGCCGCT TTGACTTCCC GGATGAGCTG CGGCCCGCTG TGGTGCATGG TGTCTGGTAC
TTCAATAGCC CCTACCCCAA GAACTACCCC CCGGTGGTCT TCAAGTCGCG CACCCAAGTA
GTCCACGAGA GCTTCCAGGG CCGCAGCCGC CTCCTGGGGG ACCTGGGCCT GCGAAACTGC
ACCCTCCTGC TCAGCAACGT CAGCCCCGAG CTGGGCGGGA AGTACTACTT CCGTGGGGAC
CTGGGCGGCT ACAACCAGTA CACCTTCTCA GAGCACAGCG TCCTGGATAT CGTCAACACC
CCCAACATCG TGGTGCCCCC AGAGGTGGTG GCAGGCACGG AGGTGGAGGT CAGCTGCATG
GTGCCGGACA ACTGCCCAGA GCTGCGCCCT GAGCTGAGCT GGCTGGGCCA CGAGGGGCTG
GGGGAGCCCG CTGTGCTGGG CCGGCTGCGG GAGGACGAGG GCACCTGGGT GCAGGTGTCA
CTGCTGCACT TCGTGCCCAC GAGGGAGGCC AACGGCCACA GGCTGGGCTG CCAGGCCTCC
TTCCCCAACA CCACCCTGCA GTTCGAGGGC TACGCCAGCA TGGACGTCAA GTACCCCCCG
GTGATTGTGG AGATGAACTC CTCGGTGGAG GCCATCGAGG GCTCCCACGT GAGCCTGCTC
TGTGGGGCTG ACAGCAACCC CCCGCCGCTG CTGACCTGGA TGCGGGACGG GACAGTCCTC
CGGGAGGCGG TGGCCGAGAG CCTGCTCCTG GAGCTGGAGG AGGTGACCCC CGCCGAAGAC
GGCGTCTATG CCTGCCTGGC CGAGAATGCC TATGGCCAGG ACAACCGCAC CGTGGGGCTC
AGTGTCATGT ATGCACCCTG GAAGCCAACA GTGAACGGGA CAATGGTGGC CGTAGAGGGG
GAGACGGTCT CTATCTTGTG CTCCACACAG AGCAACCCGG ACCCTATTCT CACCATCTTC
AAGGAGAAGC AGATCCTGTC CACGGTCATC TACGAGAGCG AGCTGCAGCT GGAGCTGCCG
GCCGTGTCAC CCGAGGATGA TGGAGAGTAC TGGTGTGTGG CTGAGAACCA GTATGGCCAG
AGGGCCACCG CCTTCAACCT GTCTGTGGAG TTCGCCCCTG TGCTCCTCCT GGAGTCCCAC
TGCGCGGCAG CCCGAGACAC GGTGCAGTGC CTGTGCGTGG TGAAGTCCAA CCCGGAGCCG
TCCGTGGCCT TTGAGCTGCC ATCGCGCAAT GTGACCGTGA ACGAGAGCGA GCGGGAGTTC
GTGTACTCGG AGCGCAGCGG CCTCGTGCTC ACCAGCATCC TCACGCTGCG GGGGCAGGCC
CAGGCCCCGC CCCGCGTCAT CTGCACCGCG AGGAACCTCT ATGGCGCCAA GAGCCTGGAG
CTGCCCTTCC AGGGAGCCCA TCGACTGATG TGGGCCAAGA TCGGGCCTGT GGGCGCCGTG
GTCGCCTTTG CCATCCTGAT TGCCATCGTC TGCTACATTA CCCAGACACG CAGGAAAAAG
AACGTGACAG AGAGCCCCAG CTTCTCGGCA GGGGACAACC CTCCCGTCCT GTTCAGCAGC
GACTTCCGCA TCTCTGGGGC ACCAGAGAAG TACGAGTCCA AAGAGGTTTC TACCCTGGAA
TCTCACTGA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OHu13785
Clone ID Related Accession (Same CDS sequence) NM_002361
Accession Version NM_002361.3 Documents for ORF clone product in dufault vector
Sequence Information ORF Nucleotide Sequence (Length: 1881bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags COA
ORF Insert Method CloneEZ® Seamless cloning technology
Structure linear
Update Date 15-MAR-2015
Organism Homo sapiens (human)
Product myelin-associated glycoprotein isoform a precursor
Comment REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from DC331168.1, AK223562.1 and BC093045.1. On or before Aug 31, 2013 this sequence version replaced gi:530416604, gi:18104955. Transcript Variant: This variant (1) lacks exon 11 and has the stop codon in exon 12, as compared to variant 2. Isoform a is 44 aa longer and contains a different carboxy terminus when compared to isoform b. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AK222649.1, AK223562.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2145743, SAMEA2154665 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: full length.

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
1501
1561
1621
1681
1741
1801
1861
ATGATATTCC TCACGGCACT GCCTCTGTTC TGGATTATGA TTTCAGCCTC CCGAGGGGGT 
CACTGGGGTG CCTGGATGCC CTCGTCCATC TCGGCCTTCG AAGGCACGTG CGTCTCCATC
CCCTGCCGCT TTGACTTCCC GGATGAGCTG CGGCCCGCTG TGGTGCATGG TGTCTGGTAC
TTCAATAGCC CCTACCCCAA GAACTACCCC CCGGTGGTCT TCAAGTCGCG CACCCAAGTA
GTCCACGAGA GCTTCCAGGG CCGCAGCCGC CTCCTGGGGG ACCTGGGCCT GCGAAACTGC
ACCCTCCTGC TCAGCAACGT CAGCCCCGAG CTGGGCGGGA AGTACTACTT CCGTGGGGAC
CTGGGCGGCT ACAACCAGTA CACCTTCTCA GAGCACAGCG TCCTGGATAT CGTCAACACC
CCCAACATCG TGGTGCCCCC AGAGGTGGTG GCAGGCACGG AGGTGGAGGT CAGCTGCATG
GTGCCGGACA ACTGCCCAGA GCTGCGCCCT GAGCTGAGCT GGCTGGGCCA CGAGGGGCTG
GGGGAGCCCG CTGTGCTGGG CCGGCTGCGG GAGGACGAGG GCACCTGGGT GCAGGTGTCA
CTGCTGCACT TCGTGCCCAC GAGGGAGGCC AACGGCCACA GGCTGGGCTG CCAGGCCTCC
TTCCCCAACA CCACCCTGCA GTTCGAGGGC TACGCCAGCA TGGACGTCAA GTACCCCCCG
GTGATTGTGG AGATGAACTC CTCGGTGGAG GCCATCGAGG GCTCCCACGT GAGCCTGCTC
TGTGGGGCTG ACAGCAACCC CCCGCCGCTG CTGACCTGGA TGCGGGACGG GACAGTCCTC
CGGGAGGCGG TGGCCGAGAG CCTGCTCCTG GAGCTGGAGG AGGTGACCCC CGCCGAAGAC
GGCGTCTATG CCTGCCTGGC CGAGAATGCC TATGGCCAGG ACAACCGCAC CGTGGGGCTC
AGTGTCATGT ATGCACCCTG GAAGCCAACA GTGAACGGGA CAATGGTGGC CGTAGAGGGG
GAGACGGTCT CTATCTTGTG CTCCACACAG AGCAACCCGG ACCCTATTCT CACCATCTTC
AAGGAGAAGC AGATCCTGTC CACGGTCATC TACGAGAGCG AGCTGCAGCT GGAGCTGCCG
GCCGTGTCAC CCGAGGATGA TGGAGAGTAC TGGTGTGTGG CTGAGAACCA GTATGGCCAG
AGGGCCACCG CCTTCAACCT GTCTGTGGAG TTCGCCCCTG TGCTCCTCCT GGAGTCCCAC
TGCGCGGCAG CCCGAGACAC GGTGCAGTGC CTGTGCGTGG TGAAGTCCAA CCCGGAGCCG
TCCGTGGCCT TTGAGCTGCC ATCGCGCAAT GTGACCGTGA ACGAGAGCGA GCGGGAGTTC
GTGTACTCGG AGCGCAGCGG CCTCGTGCTC ACCAGCATCC TCACGCTGCG GGGGCAGGCC
CAGGCCCCGC CCCGCGTCAT CTGCACCGCG AGGAACCTCT ATGGCGCCAA GAGCCTGGAG
CTGCCCTTCC AGGGAGCCCA TCGACTGATG TGGGCCAAGA TCGGGCCTGT GGGCGCCGTG
GTCGCCTTTG CCATCCTGAT TGCCATCGTC TGCTACATTA CCCAGACACG CAGGAAAAAG
AACGTGACAG AGAGCCCCAG CTTCTCGGCA GGGGACAACC CTCCCGTCCT GTTCAGCAGC
GACTTCCGCA TCTCTGGGGC ACCAGAGAAG TACGAGAGCG AGAGGCGCCT GGGATCTGAG
AGGAGGCTGC TGGGCCTTCG GGGTGAGCCC CCAGAGCTGG ACCTGAGCTA TTCTCACTCG
GACCTGGGGA AACGGCCCAC CAAGGACAGC TACACGCTGA CGGAGGAGCT AGCTGAGTAT
GCTGAAATCC GGGTCAAGTG A

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq NP_002352.1
CDS199..2079
Misc Feature(1)262..615(+)
Misc Feature(2)277..>546(+)
Misc Feature(3)493..495(+)
Misc Feature(4)514..516(+)
Misc Feature(5)550..582(+)
Misc Feature(6)619..864(+)
Misc Feature(7)865..867(+)
Misc Feature(8)916..1164(+)
Misc Feature(9)934..936(+)
Misc Feature(10)958..1164(+)
Misc Feature(11)1141..1143(+)
Misc Feature(12)1192..1194(+)
Misc Feature(13)1195..1425(+)
Misc Feature(14)1207..1398(+)
Misc Feature(15)1414..1416(+)
Misc Feature(16)1546..1548(+)
Misc Feature(17)1558..1560(+)
Misc Feature(18)1747..1806(+)
Misc Feature(19)2056..2058(+)
Exon (1)1..119
Gene:MAG
Gene Synonym:
Exon (2)120..175
Gene:MAG
Gene Synonym:
Exon (3)176..244
Gene:MAG
Gene Synonym:
Exon (4)245..613
Gene:MAG
Gene Synonym:
Exon (5)614..910
Gene:MAG
Gene Synonym:
Exon (6)911..1168
Gene:MAG
Gene Synonym:
Exon (7)1169..1429
Gene:MAG
Gene Synonym:
Exon (8)1430..1717
Gene:MAG
Gene Synonym:
Exon (9)1718..1814
Gene:MAG
Gene Synonym:
Exon (10)1815..1914
Gene:MAG
Gene Synonym:
Exon (11)1915..2432
Gene:MAG
Gene Synonym:
Translation

Target ORF information:

RefSeq Version NM_002361
Organism Homo sapiens (human)
Definition Homo sapiens myelin associated glycoprotein (MAG), transcript variant 1, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
NM_002361

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
1501
1561
1621
1681
1741
1801
1861
ATGATATTCC TCACGGCACT GCCTCTGTTC TGGATTATGA TTTCAGCCTC CCGAGGGGGT 
CACTGGGGTG CCTGGATGCC CTCGTCCATC TCGGCCTTCG AAGGCACGTG CGTCTCCATC
CCCTGCCGCT TTGACTTCCC GGATGAGCTG CGGCCCGCTG TGGTGCATGG TGTCTGGTAC
TTCAATAGCC CCTACCCCAA GAACTACCCC CCGGTGGTCT TCAAGTCGCG CACCCAAGTA
GTCCACGAGA GCTTCCAGGG CCGCAGCCGC CTCCTGGGGG ACCTGGGCCT GCGAAACTGC
ACCCTCCTGC TCAGCAACGT CAGCCCCGAG CTGGGCGGGA AGTACTACTT CCGTGGGGAC
CTGGGCGGCT ACAACCAGTA CACCTTCTCA GAGCACAGCG TCCTGGATAT CGTCAACACC
CCCAACATCG TGGTGCCCCC AGAGGTGGTG GCAGGCACGG AGGTGGAGGT CAGCTGCATG
GTGCCGGACA ACTGCCCAGA GCTGCGCCCT GAGCTGAGCT GGCTGGGCCA CGAGGGGCTG
GGGGAGCCCG CTGTGCTGGG CCGGCTGCGG GAGGACGAGG GCACCTGGGT GCAGGTGTCA
CTGCTGCACT TCGTGCCCAC GAGGGAGGCC AACGGCCACA GGCTGGGCTG CCAGGCCTCC
TTCCCCAACA CCACCCTGCA GTTCGAGGGC TACGCCAGCA TGGACGTCAA GTACCCCCCG
GTGATTGTGG AGATGAACTC CTCGGTGGAG GCCATCGAGG GCTCCCACGT GAGCCTGCTC
TGTGGGGCTG ACAGCAACCC CCCGCCGCTG CTGACCTGGA TGCGGGACGG GACAGTCCTC
CGGGAGGCGG TGGCCGAGAG CCTGCTCCTG GAGCTGGAGG AGGTGACCCC CGCCGAAGAC
GGCGTCTATG CCTGCCTGGC CGAGAATGCC TATGGCCAGG ACAACCGCAC CGTGGGGCTC
AGTGTCATGT ATGCACCCTG GAAGCCAACA GTGAACGGGA CAATGGTGGC CGTAGAGGGG
GAGACGGTCT CTATCTTGTG CTCCACACAG AGCAACCCGG ACCCTATTCT CACCATCTTC
AAGGAGAAGC AGATCCTGTC CACGGTCATC TACGAGAGCG AGCTGCAGCT GGAGCTGCCG
GCCGTGTCAC CCGAGGATGA TGGAGAGTAC TGGTGTGTGG CTGAGAACCA GTATGGCCAG
AGGGCCACCG CCTTCAACCT GTCTGTGGAG TTCGCCCCTG TGCTCCTCCT GGAGTCCCAC
TGCGCGGCAG CCCGAGACAC GGTGCAGTGC CTGTGCGTGG TGAAGTCCAA CCCGGAGCCG
TCCGTGGCCT TTGAGCTGCC ATCGCGCAAT GTGACCGTGA ACGAGAGCGA GCGGGAGTTC
GTGTACTCGG AGCGCAGCGG CCTCGTGCTC ACCAGCATCC TCACGCTGCG GGGGCAGGCC
CAGGCCCCGC CCCGCGTCAT CTGCACCGCG AGGAACCTCT ATGGCGCCAA GAGCCTGGAG
CTGCCCTTCC AGGGAGCCCA TCGACTGATG TGGGCCAAGA TCGGGCCTGT GGGCGCCGTG
GTCGCCTTTG CCATCCTGAT TGCCATCGTC TGCTACATTA CCCAGACACG CAGGAAAAAG
AACGTGACAG AGAGCCCCAG CTTCTCGGCA GGGGACAACC CTCCCGTCCT GTTCAGCAGC
GACTTCCGCA TCTCTGGGGC ACCAGAGAAG TACGAGAGCG AGAGGCGCCT GGGATCTGAG
AGGAGGCTGC TGGGCCTTCG GGGTGAGCCC CCAGAGCTGG ACCTGAGCTA TTCTCACTCG
GACCTGGGGA AACGGCCCAC CAAGGACAGC TACACGCTGA CGGAGGAGCT AGCTGAGTAT
GCTGAAATCC GGGTCAAGTG A

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OHu13781
Clone ID Related Accession (Same CDS sequence) NM_001199216
Accession Version NM_001199216.1 Documents for ORF clone product in dufault vector
Sequence Information ORF Nucleotide Sequence (Length: 1806bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags COA
ORF Insert Method CloneEZ® Seamless cloning technology
Structure linear
Update Date 15-MAR-2015
Organism Homo sapiens (human)
Product myelin-associated glycoprotein isoform c
Comment REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from DC331168.1, AK308976.1 and BC093045.1. Transcript Variant: This variant (3) differs in the 5' UTR and coding sequence compared to variant 1. The resulting isoform (c) is shorter at the N-terminus compared to isoform a. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AK294644.1, AK308976.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2145743, SAMEA2157437 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: full length.

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
1501
1561
1621
1681
1741
1801
ATGCCCTCGT CCATCTCGGC CTTCGAAGGC ACGTGCGTCT CCATCCCCTG CCGCTTTGAC 
TTCCCGGATG AGCTGCGGCC CGCTGTGGTG CATGGTGTCT GGTACTTCAA TAGCCCCTAC
CCCAAGAACT ACCCCCCGGT GGTCTTCAAG TCGCGCACCC AAGTAGTCCA CGAGAGCTTC
CAGGGCCGCA GCCGCCTCCT GGGGGACCTG GGCCTGCGAA ACTGCACCCT CCTGCTCAGC
AACGTCAGCC CCGAGCTGGG CGGGAAGTAC TACTTCCGTG GGGACCTGGG CGGCTACAAC
CAGTACACCT TCTCAGAGCA CAGCGTCCTG GATATCGTCA ACACCCCCAA CATCGTGGTG
CCCCCAGAGG TGGTGGCAGG CACGGAGGTG GAGGTCAGCT GCATGGTGCC GGACAACTGC
CCAGAGCTGC GCCCTGAGCT GAGCTGGCTG GGCCACGAGG GGCTGGGGGA GCCCGCTGTG
CTGGGCCGGC TGCGGGAGGA CGAGGGCACC TGGGTGCAGG TGTCACTGCT GCACTTCGTG
CCCACGAGGG AGGCCAACGG CCACAGGCTG GGCTGCCAGG CCTCCTTCCC CAACACCACC
CTGCAGTTCG AGGGCTACGC CAGCATGGAC GTCAAGTACC CCCCGGTGAT TGTGGAGATG
AACTCCTCGG TGGAGGCCAT CGAGGGCTCC CACGTGAGCC TGCTCTGTGG GGCTGACAGC
AACCCCCCGC CGCTGCTGAC CTGGATGCGG GACGGGACAG TCCTCCGGGA GGCGGTGGCC
GAGAGCCTGC TCCTGGAGCT GGAGGAGGTG ACCCCCGCCG AAGACGGCGT CTATGCCTGC
CTGGCCGAGA ATGCCTATGG CCAGGACAAC CGCACCGTGG GGCTCAGTGT CATGTATGCA
CCCTGGAAGC CAACAGTGAA CGGGACAATG GTGGCCGTAG AGGGGGAGAC GGTCTCTATC
TTGTGCTCCA CACAGAGCAA CCCGGACCCT ATTCTCACCA TCTTCAAGGA GAAGCAGATC
CTGTCCACGG TCATCTACGA GAGCGAGCTG CAGCTGGAGC TGCCGGCCGT GTCACCCGAG
GATGATGGAG AGTACTGGTG TGTGGCTGAG AACCAGTATG GCCAGAGGGC CACCGCCTTC
AACCTGTCTG TGGAGTTCGC CCCTGTGCTC CTCCTGGAGT CCCACTGCGC GGCAGCCCGA
GACACGGTGC AGTGCCTGTG CGTGGTGAAG TCCAACCCGG AGCCGTCCGT GGCCTTTGAG
CTGCCATCGC GCAATGTGAC CGTGAACGAG AGCGAGCGGG AGTTCGTGTA CTCGGAGCGC
AGCGGCCTCG TGCTCACCAG CATCCTCACG CTGCGGGGGC AGGCCCAGGC CCCGCCCCGC
GTCATCTGCA CCGCGAGGAA CCTCTATGGC GCCAAGAGCC TGGAGCTGCC CTTCCAGGGA
GCCCATCGAC TGATGTGGGC CAAGATCGGG CCTGTGGGCG CCGTGGTCGC CTTTGCCATC
CTGATTGCCA TCGTCTGCTA CATTACCCAG ACACGCAGGA AAAAGAACGT GACAGAGAGC
CCCAGCTTCT CGGCAGGGGA CAACCCTCCC GTCCTGTTCA GCAGCGACTT CCGCATCTCT
GGGGCACCAG AGAAGTACGA GAGCGAGAGG CGCCTGGGAT CTGAGAGGAG GCTGCTGGGC
CTTCGGGGTG AGCCCCCAGA GCTGGACCTG AGCTATTCTC ACTCGGACCT GGGGAAACGG
CCCACCAAGG ACAGCTACAC GCTGACGGAG GAGCTAGCTG AGTATGCTGA AATCCGGGTC
AAGTGA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq NP_001186145.1
CDS261..2066
Misc Feature(1)177..179(+)
Misc Feature(2)261..602(+)
Misc Feature(3)264..>533(+)
Misc Feature(4)537..569(+)
Misc Feature(5)606..851(+)
Misc Feature(6)903..1151(+)
Misc Feature(7)945..1151(+)
Misc Feature(8)1182..1412(+)
Misc Feature(9)1194..1385(+)
Exon (1)1..119
Gene:MAG
Gene Synonym:
Exon (2)120..175
Gene:MAG
Gene Synonym:
Exon (3)176..231
Gene:MAG
Gene Synonym:
Exon (4)232..600
Gene:MAG
Gene Synonym:
Exon (5)601..897
Gene:MAG
Gene Synonym:
Exon (6)898..1155
Gene:MAG
Gene Synonym:
Exon (7)1156..1416
Gene:MAG
Gene Synonym:
Exon (8)1417..1704
Gene:MAG
Gene Synonym:
Exon (9)1705..1801
Gene:MAG
Gene Synonym:
Exon (10)1802..1901
Gene:MAG
Gene Synonym:
Exon (11)1902..2419
Gene:MAG
Gene Synonym:
Translation

Target ORF information:

RefSeq Version NM_001199216
Organism Homo sapiens (human)
Definition Homo sapiens myelin associated glycoprotein (MAG), transcript variant 3, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
NM_001199216

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
1501
1561
1621
1681
1741
1801
ATGCCCTCGT CCATCTCGGC CTTCGAAGGC ACGTGCGTCT CCATCCCCTG CCGCTTTGAC 
TTCCCGGATG AGCTGCGGCC CGCTGTGGTG CATGGTGTCT GGTACTTCAA TAGCCCCTAC
CCCAAGAACT ACCCCCCGGT GGTCTTCAAG TCGCGCACCC AAGTAGTCCA CGAGAGCTTC
CAGGGCCGCA GCCGCCTCCT GGGGGACCTG GGCCTGCGAA ACTGCACCCT CCTGCTCAGC
AACGTCAGCC CCGAGCTGGG CGGGAAGTAC TACTTCCGTG GGGACCTGGG CGGCTACAAC
CAGTACACCT TCTCAGAGCA CAGCGTCCTG GATATCGTCA ACACCCCCAA CATCGTGGTG
CCCCCAGAGG TGGTGGCAGG CACGGAGGTG GAGGTCAGCT GCATGGTGCC GGACAACTGC
CCAGAGCTGC GCCCTGAGCT GAGCTGGCTG GGCCACGAGG GGCTGGGGGA GCCCGCTGTG
CTGGGCCGGC TGCGGGAGGA CGAGGGCACC TGGGTGCAGG TGTCACTGCT GCACTTCGTG
CCCACGAGGG AGGCCAACGG CCACAGGCTG GGCTGCCAGG CCTCCTTCCC CAACACCACC
CTGCAGTTCG AGGGCTACGC CAGCATGGAC GTCAAGTACC CCCCGGTGAT TGTGGAGATG
AACTCCTCGG TGGAGGCCAT CGAGGGCTCC CACGTGAGCC TGCTCTGTGG GGCTGACAGC
AACCCCCCGC CGCTGCTGAC CTGGATGCGG GACGGGACAG TCCTCCGGGA GGCGGTGGCC
GAGAGCCTGC TCCTGGAGCT GGAGGAGGTG ACCCCCGCCG AAGACGGCGT CTATGCCTGC
CTGGCCGAGA ATGCCTATGG CCAGGACAAC CGCACCGTGG GGCTCAGTGT CATGTATGCA
CCCTGGAAGC CAACAGTGAA CGGGACAATG GTGGCCGTAG AGGGGGAGAC GGTCTCTATC
TTGTGCTCCA CACAGAGCAA CCCGGACCCT ATTCTCACCA TCTTCAAGGA GAAGCAGATC
CTGTCCACGG TCATCTACGA GAGCGAGCTG CAGCTGGAGC TGCCGGCCGT GTCACCCGAG
GATGATGGAG AGTACTGGTG TGTGGCTGAG AACCAGTATG GCCAGAGGGC CACCGCCTTC
AACCTGTCTG TGGAGTTCGC CCCTGTGCTC CTCCTGGAGT CCCACTGCGC GGCAGCCCGA
GACACGGTGC AGTGCCTGTG CGTGGTGAAG TCCAACCCGG AGCCGTCCGT GGCCTTTGAG
CTGCCATCGC GCAATGTGAC CGTGAACGAG AGCGAGCGGG AGTTCGTGTA CTCGGAGCGC
AGCGGCCTCG TGCTCACCAG CATCCTCACG CTGCGGGGGC AGGCCCAGGC CCCGCCCCGC
GTCATCTGCA CCGCGAGGAA CCTCTATGGC GCCAAGAGCC TGGAGCTGCC CTTCCAGGGA
GCCCATCGAC TGATGTGGGC CAAGATCGGG CCTGTGGGCG CCGTGGTCGC CTTTGCCATC
CTGATTGCCA TCGTCTGCTA CATTACCCAG ACACGCAGGA AAAAGAACGT GACAGAGAGC
CCCAGCTTCT CGGCAGGGGA CAACCCTCCC GTCCTGTTCA GCAGCGACTT CCGCATCTCT
GGGGCACCAG AGAAGTACGA GAGCGAGAGG CGCCTGGGAT CTGAGAGGAG GCTGCTGGGC
CTTCGGGGTG AGCCCCCAGA GCTGGACCTG AGCTATTCTC ACTCGGACCT GGGGAAACGG
CCCACCAAGG ACAGCTACAC GCTGACGGAG GAGCTAGCTG AGTATGCTGA AATCCGGGTC
AAGTGA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

book

LRP1 assembles unique co-receptor systems to initiate cell signaling in response to tissue-type plasminogen activator and myelin-associated glycoprotein
J. Biol. Chem. 288 (47), 34009-34018 (2013)
Mantuano E, Lam MS and Gonias SL.


book

The possible relationship between allergic manifestations and elevated serum levels of brain specific auto-antibodies in autistic children
J. Neuroimmunol. 261 (1-2), 77-81 (2013)
Mostafa GA and Al-Ayadhi LY.


book

Loss of myelin-associated glycoprotein in kearns-sayre syndrome
Arch. Neurol. 69 (4), 490-499 (2012)
Lax NZ, Campbell GR, Reeve AK, Ohno N, Zambonin J, Blakely EL, Taylor RW, Bonilla E, Tanji K, DiMauro S, Jaros E, Lassmann H, Turnbull DM and Mahad DJ.


book

Non-anti-MAG DADS neuropathy as a variant of CIDP: clinical, electrophysiological, laboratory features and response to treatment in 10 cases
Eur. J. Neurol. 18 (6), 899-905 (2011)
Larue S, Bombelli F, Viala K, Neil J, Maisonobe T, Bouche P, Musset L, Fournier E and Leger JM.


book

N-CAM dysfunction and unexpected accumulation of PSA-NCAM in brain of adult-onset autosomal-dominant leukodystrophy
Brain Pathol. 20 (2), 431-440 (2010)
Piccinini M, Buccinna B, De Marco G, Lupino E, Ramondetti C, Grifoni S, Votta B, Giordana MT and Rinaudo MT.


book

Molecular cloning of human myelin-associated glycoprotein
J. Neurosci. Res. 24 (2), 137-142 (1989)
Spagnol G, Williams M, Srinivasan J, Golier J, Bauer D, Lebo RV and Latov N.


book

cDNA cloning and amino acid sequence for human myelin-associated glycoprotein
Biochem. Biophys. Res. Commun. 163 (3), 1473-1480 (1989)
Sato S, Fujita N, Kurihara T, Kuwano R, Sakimura K, Takahashi Y and Miyatake T.


book

Myelin-associated glycoprotein in demyelinating disorders
Crit Rev Neurobiol 5 (1), 1-28 (1989)
Quarles RH.


book

The myelin-associated glycoprotein gene: mapping to human chromosome 19 and mouse chromosome 7 and expression in quivering mice
Genomics 1 (2), 107-112 (1987)
Barton DE, Arquint M, Roder J, Dunn R and Francke U.


book

Characterization of binding properties of the myelin-associated glycoprotein to extracellular matrix constituents
EMBO J. 6 (10), 2875-2883 (1987)
Fahrig T, Landa C, Pesheva P, Kuhn K and Schachner M.


 
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