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MAGEA6 cDNA ORF clone, Homo sapiens (human)

Gene Symbol MAGEA6
Entrez Gene ID 4105
Full Name melanoma antigen family A6
Synonyms CT1.6, MAGE-3b, MAGE3B, MAGE6
General protein information
Preferred Names
melanoma-associated antigen 6
Names
melanoma-associated antigen 6
MAGE-6 antigen
MAGE3B antigen
cancer/testis antigen 1.6
cancer/testis antigen family 1, member 6
Gene Type protein-coding
Organism Homo sapiens (human)
Genome

X

Xq28

Summary This gene is a member of the MAGEA gene family. The members of this family encode proteins with 50 to 80% sequence identity to each other. The promoters and first exons of the MAGEA genes show considerable variability, suggesting that the existence of this gene family enables the same function to be expressed under different transcriptional controls. The MAGEA genes are clustered at chromosomal location Xq28. They have been implicated in some hereditary disorders, such as dyskeratosis congenita. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2013]. lac of sum
Disorder MIM:

300176


mRNA and Protein(s)

mRNA Protein Name
XM_011531162 XP_011529464 melanoma-associated antigen 6 isoform X1
NM_005363 NP_005354 melanoma-associated antigen 6
NM_175868 NP_787064 melanoma-associated antigen 6


Homo sapiens (human) MAGEA3 NP_005353.1
Homo sapiens (human) MAGEA6 NP_787064.1
Macaca mulatta (Rhesus monkey) LOC711544 XP_001100355.2
Macaca mulatta (Rhesus monkey) MAGEA3 XP_001094934.2


GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following MAGEA6 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the MAGEA6 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

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***CloneID RefSeq Accession Definition **Vector *Turnaround time Price (USD) Select
OHu07419
XM_011531162 PREDICTED: Homo sapiens melanoma antigen family A6 (MAGEA6), transcript variant X1, mRNA. pcDNA3.1+/C-(K)DYK or customized vector
in pcDNA3.1+/C-(K)DYK
$99.50-$139.30
$199.00
OHu07419
NM_005363 Homo sapiens melanoma antigen family A6 (MAGEA6), transcript variant 1, mRNA. pcDNA3.1+/C-(K)DYK or customized vector
in pcDNA3.1+/C-(K)DYK
$99.50-$139.30
$199.00
OHu07419
NM_175868 Homo sapiens melanoma antigen family A6 (MAGEA6), transcript variant 2, mRNA. pcDNA3.1+/C-(K)DYK or customized vector
in pcDNA3.1+/C-(K)DYK
$99.50-$139.30
$199.00

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.


CloneID OHu07419
Clone ID Related Accession (Same CDS sequence) NM_005363 , NM_175868 , XM_011531162
Accession Version XM_011531162.1 Documents for ORF clone product in dufault vector
Sequence Information ORF Nucleotide Sequence (Length: 945bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags COA
ORF Insert Method CloneEZ® Seamless cloning technology
Insert Structure linear
Update Date 12-MAR-2015
Organism Homo sapiens (human)
Product melanoma-associated antigen 6 isoform X1
Comment MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NT_011681.17) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Homo sapiens Annotation Release 107 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 6.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
ATGCCTCTTG AGCAGAGGAG TCAGCACTGC AAGCCTGAAG AAGGCCTTGA GGCCCGAGGA 
GAGGCCCTGG GCCTGGTGGG TGCGCAGGCT CCTGCTACTG AGGAGCAGGA GGCTGCCTCC
TCCTCTTCTA CTCTAGTTGA AGTCACCCTG GGGGAGGTGC CTGCTGCCGA GTCACCAGAT
CCTCCCCAGA GTCCTCAGGG AGCCTCCAGC CTCCCCACTA CCATGAACTA CCCTCTCTGG
AGCCAATCCT ATGAGGACTC CAGCAACCAA GAAGAGGAGG GGCCAAGCAC CTTCCCTGAC
CTGGAGTCTG AGTTCCAAGC AGCACTCAGT AGGAAGGTGG CCAAGTTGGT TCATTTTCTG
CTCCTCAAGT ATCGAGCCAG GGAGCCGGTC ACAAAGGCAG AAATGCTGGG GAGTGTCGTC
GGAAATTGGC AGTACTTCTT TCCTGTGATC TTCAGCAAAG CTTCCGATTC CTTGCAGCTG
GTCTTTGGCA TCGAGCTGAT GGAAGTGGAC CCCATCGGCC ACGTGTACAT CTTTGCCACC
TGCCTGGGCC TCTCCTACGA TGGCCTGCTG GGTGACAATC AGATCATGCC CAAGACAGGC
TTCCTGATAA TCATCCTGGC CATAATCGCA AAAGAGGGCG ACTGTGCCCC TGAGGAGAAA
ATCTGGGAGG AGCTGAGTGT GTTAGAGGTG TTTGAGGGGA GGGAAGACAG TATCTTCGGG
GATCCCAAGA AGCTGCTCAC CCAATATTTC GTGCAGGAAA ACTACCTGGA GTACCGGCAG
GTCCCCGGCA GTGATCCTGC ATGCTATGAG TTCCTGTGGG GTCCAAGGGC CCTCATTGAA
ACCAGCTATG TGAAAGTCCT GCACCATATG GTAAAGATCA GTGGAGGACC TCGCATTTCC
TACCCACTCC TGCATGAGTG GGCTTTGAGA GAGGGGGAAG AGTGA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq XP_011529464.1
CDS366..1310
Misc Feature(1)372..659(+)
Misc Feature(2)711..1223(+)
Translation

Target ORF information:

RefSeq Version XM_011531162
Organism Homo sapiens (human)
Definition PREDICTED: Homo sapiens melanoma antigen family A6 (MAGEA6), transcript variant X1, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
XM_011531162

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
ATGCCTCTTG AGCAGAGGAG TCAGCACTGC AAGCCTGAAG AAGGCCTTGA GGCCCGAGGA 
GAGGCCCTGG GCCTGGTGGG TGCGCAGGCT CCTGCTACTG AGGAGCAGGA GGCTGCCTCC
TCCTCTTCTA CTCTAGTTGA AGTCACCCTG GGGGAGGTGC CTGCTGCCGA GTCACCAGAT
CCTCCCCAGA GTCCTCAGGG AGCCTCCAGC CTCCCCACTA CCATGAACTA CCCTCTCTGG
AGCCAATCCT ATGAGGACTC CAGCAACCAA GAAGAGGAGG GGCCAAGCAC CTTCCCTGAC
CTGGAGTCTG AGTTCCAAGC AGCACTCAGT AGGAAGGTGG CCAAGTTGGT TCATTTTCTG
CTCCTCAAGT ATCGAGCCAG GGAGCCGGTC ACAAAGGCAG AAATGCTGGG GAGTGTCGTC
GGAAATTGGC AGTACTTCTT TCCTGTGATC TTCAGCAAAG CTTCCGATTC CTTGCAGCTG
GTCTTTGGCA TCGAGCTGAT GGAAGTGGAC CCCATCGGCC ACGTGTACAT CTTTGCCACC
TGCCTGGGCC TCTCCTACGA TGGCCTGCTG GGTGACAATC AGATCATGCC CAAGACAGGC
TTCCTGATAA TCATCCTGGC CATAATCGCA AAAGAGGGCG ACTGTGCCCC TGAGGAGAAA
ATCTGGGAGG AGCTGAGTGT GTTAGAGGTG TTTGAGGGGA GGGAAGACAG TATCTTCGGG
GATCCCAAGA AGCTGCTCAC CCAATATTTC GTGCAGGAAA ACTACCTGGA GTACCGGCAG
GTCCCCGGCA GTGATCCTGC ATGCTATGAG TTCCTGTGGG GTCCAAGGGC CCTCATTGAA
ACCAGCTATG TGAAAGTCCT GCACCATATG GTAAAGATCA GTGGAGGACC TCGCATTTCC
TACCCACTCC TGCATGAGTG GGCTTTGAGA GAGGGGGAAG AGTGA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OHu07419
Clone ID Related Accession (Same CDS sequence) NM_005363 , NM_175868 , XM_011531162
Accession Version NM_005363.2 Documents for ORF clone product in dufault vector
Sequence Information ORF Nucleotide Sequence (Length: 945bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags COA
ORF Insert Method CloneEZ® Seamless cloning technology
Insert Structure linear
Update Date 15-MAR-2015
Organism Homo sapiens (human)
Product melanoma-associated antigen 6
Comment REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from BC041599.1 and BM843807.1. On Mar 18, 2003 this sequence version replaced gi:4885468. Transcript Variant: This variant (1) differs in the 5' UTR, compared to variant 2. Variants 1 and 2 encode the same protein. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AK289437.1, BC067731.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2148093, SAMEA2148874 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
ATGCCTCTTG AGCAGAGGAG TCAGCACTGC AAGCCTGAAG AAGGCCTTGA GGCCCGAGGA 
GAGGCCCTGG GCCTGGTGGG TGCGCAGGCT CCTGCTACTG AGGAGCAGGA GGCTGCCTCC
TCCTCTTCTA CTCTAGTTGA AGTCACCCTG GGGGAGGTGC CTGCTGCCGA GTCACCAGAT
CCTCCCCAGA GTCCTCAGGG AGCCTCCAGC CTCCCCACTA CCATGAACTA CCCTCTCTGG
AGCCAATCCT ATGAGGACTC CAGCAACCAA GAAGAGGAGG GGCCAAGCAC CTTCCCTGAC
CTGGAGTCTG AGTTCCAAGC AGCACTCAGT AGGAAGGTGG CCAAGTTGGT TCATTTTCTG
CTCCTCAAGT ATCGAGCCAG GGAGCCGGTC ACAAAGGCAG AAATGCTGGG GAGTGTCGTC
GGAAATTGGC AGTACTTCTT TCCTGTGATC TTCAGCAAAG CTTCCGATTC CTTGCAGCTG
GTCTTTGGCA TCGAGCTGAT GGAAGTGGAC CCCATCGGCC ACGTGTACAT CTTTGCCACC
TGCCTGGGCC TCTCCTACGA TGGCCTGCTG GGTGACAATC AGATCATGCC CAAGACAGGC
TTCCTGATAA TCATCCTGGC CATAATCGCA AAAGAGGGCG ACTGTGCCCC TGAGGAGAAA
ATCTGGGAGG AGCTGAGTGT GTTAGAGGTG TTTGAGGGGA GGGAAGACAG TATCTTCGGG
GATCCCAAGA AGCTGCTCAC CCAATATTTC GTGCAGGAAA ACTACCTGGA GTACCGGCAG
GTCCCCGGCA GTGATCCTGC ATGCTATGAG TTCCTGTGGG GTCCAAGGGC CCTCATTGAA
ACCAGCTATG TGAAAGTCCT GCACCATATG GTAAAGATCA GTGGAGGACC TCGCATTTCC
TACCCACTCC TGCATGAGTG GGCTTTGAGA GAGGGGGAAG AGTGA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq NP_005354.1
CDS195..1139
Misc Feature(1)81..83(+)
Misc Feature(2)201..488(+)
Misc Feature(3)540..1052(+)
Exon (1)1..63
Gene:MAGEA6
Gene Synonym:
Exon (2)64..129
Gene:MAGEA6
Gene Synonym:
Exon (3)130..1698
Gene:MAGEA6
Gene Synonym:
Translation

Target ORF information:

RefSeq Version NM_005363
Organism Homo sapiens (human)
Definition Homo sapiens melanoma antigen family A6 (MAGEA6), transcript variant 1, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
NM_005363

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
ATGCCTCTTG AGCAGAGGAG TCAGCACTGC AAGCCTGAAG AAGGCCTTGA GGCCCGAGGA 
GAGGCCCTGG GCCTGGTGGG TGCGCAGGCT CCTGCTACTG AGGAGCAGGA GGCTGCCTCC
TCCTCTTCTA CTCTAGTTGA AGTCACCCTG GGGGAGGTGC CTGCTGCCGA GTCACCAGAT
CCTCCCCAGA GTCCTCAGGG AGCCTCCAGC CTCCCCACTA CCATGAACTA CCCTCTCTGG
AGCCAATCCT ATGAGGACTC CAGCAACCAA GAAGAGGAGG GGCCAAGCAC CTTCCCTGAC
CTGGAGTCTG AGTTCCAAGC AGCACTCAGT AGGAAGGTGG CCAAGTTGGT TCATTTTCTG
CTCCTCAAGT ATCGAGCCAG GGAGCCGGTC ACAAAGGCAG AAATGCTGGG GAGTGTCGTC
GGAAATTGGC AGTACTTCTT TCCTGTGATC TTCAGCAAAG CTTCCGATTC CTTGCAGCTG
GTCTTTGGCA TCGAGCTGAT GGAAGTGGAC CCCATCGGCC ACGTGTACAT CTTTGCCACC
TGCCTGGGCC TCTCCTACGA TGGCCTGCTG GGTGACAATC AGATCATGCC CAAGACAGGC
TTCCTGATAA TCATCCTGGC CATAATCGCA AAAGAGGGCG ACTGTGCCCC TGAGGAGAAA
ATCTGGGAGG AGCTGAGTGT GTTAGAGGTG TTTGAGGGGA GGGAAGACAG TATCTTCGGG
GATCCCAAGA AGCTGCTCAC CCAATATTTC GTGCAGGAAA ACTACCTGGA GTACCGGCAG
GTCCCCGGCA GTGATCCTGC ATGCTATGAG TTCCTGTGGG GTCCAAGGGC CCTCATTGAA
ACCAGCTATG TGAAAGTCCT GCACCATATG GTAAAGATCA GTGGAGGACC TCGCATTTCC
TACCCACTCC TGCATGAGTG GGCTTTGAGA GAGGGGGAAG AGTGA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OHu07419
Clone ID Related Accession (Same CDS sequence) NM_005363 , NM_175868 , XM_011531162
Accession Version NM_175868.1 Documents for ORF clone product in dufault vector
Sequence Information ORF Nucleotide Sequence (Length: 945bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags COA
ORF Insert Method CloneEZ® Seamless cloning technology
Insert Structure linear
Update Date 15-MAR-2015
Organism Homo sapiens (human)
Product melanoma-associated antigen 6
Comment REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from BC041599.1 and BM843807.1. Transcript Variant: This variant (2) represents the longer transcript. Variants 1 and 2 encode the same protein. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BM843807.1, HY015473.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2142680, SAMEA2158188 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
ATGCCTCTTG AGCAGAGGAG TCAGCACTGC AAGCCTGAAG AAGGCCTTGA GGCCCGAGGA 
GAGGCCCTGG GCCTGGTGGG TGCGCAGGCT CCTGCTACTG AGGAGCAGGA GGCTGCCTCC
TCCTCTTCTA CTCTAGTTGA AGTCACCCTG GGGGAGGTGC CTGCTGCCGA GTCACCAGAT
CCTCCCCAGA GTCCTCAGGG AGCCTCCAGC CTCCCCACTA CCATGAACTA CCCTCTCTGG
AGCCAATCCT ATGAGGACTC CAGCAACCAA GAAGAGGAGG GGCCAAGCAC CTTCCCTGAC
CTGGAGTCTG AGTTCCAAGC AGCACTCAGT AGGAAGGTGG CCAAGTTGGT TCATTTTCTG
CTCCTCAAGT ATCGAGCCAG GGAGCCGGTC ACAAAGGCAG AAATGCTGGG GAGTGTCGTC
GGAAATTGGC AGTACTTCTT TCCTGTGATC TTCAGCAAAG CTTCCGATTC CTTGCAGCTG
GTCTTTGGCA TCGAGCTGAT GGAAGTGGAC CCCATCGGCC ACGTGTACAT CTTTGCCACC
TGCCTGGGCC TCTCCTACGA TGGCCTGCTG GGTGACAATC AGATCATGCC CAAGACAGGC
TTCCTGATAA TCATCCTGGC CATAATCGCA AAAGAGGGCG ACTGTGCCCC TGAGGAGAAA
ATCTGGGAGG AGCTGAGTGT GTTAGAGGTG TTTGAGGGGA GGGAAGACAG TATCTTCGGG
GATCCCAAGA AGCTGCTCAC CCAATATTTC GTGCAGGAAA ACTACCTGGA GTACCGGCAG
GTCCCCGGCA GTGATCCTGC ATGCTATGAG TTCCTGTGGG GTCCAAGGGC CCTCATTGAA
ACCAGCTATG TGAAAGTCCT GCACCATATG GTAAAGATCA GTGGAGGACC TCGCATTTCC
TACCCACTCC TGCATGAGTG GGCTTTGAGA GAGGGGGAAG AGTGA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq NP_787064.1
CDS259..1203
Misc Feature(1)145..147(+)
Misc Feature(2)265..552(+)
Misc Feature(3)604..1116(+)
Exon (1)1..63
Gene:MAGEA6
Gene Synonym:
Exon (2)64..193
Gene:MAGEA6
Gene Synonym:
Exon (3)194..1762
Gene:MAGEA6
Gene Synonym:
Translation

Target ORF information:

RefSeq Version NM_175868
Organism Homo sapiens (human)
Definition Homo sapiens melanoma antigen family A6 (MAGEA6), transcript variant 2, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
NM_175868

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
ATGCCTCTTG AGCAGAGGAG TCAGCACTGC AAGCCTGAAG AAGGCCTTGA GGCCCGAGGA 
GAGGCCCTGG GCCTGGTGGG TGCGCAGGCT CCTGCTACTG AGGAGCAGGA GGCTGCCTCC
TCCTCTTCTA CTCTAGTTGA AGTCACCCTG GGGGAGGTGC CTGCTGCCGA GTCACCAGAT
CCTCCCCAGA GTCCTCAGGG AGCCTCCAGC CTCCCCACTA CCATGAACTA CCCTCTCTGG
AGCCAATCCT ATGAGGACTC CAGCAACCAA GAAGAGGAGG GGCCAAGCAC CTTCCCTGAC
CTGGAGTCTG AGTTCCAAGC AGCACTCAGT AGGAAGGTGG CCAAGTTGGT TCATTTTCTG
CTCCTCAAGT ATCGAGCCAG GGAGCCGGTC ACAAAGGCAG AAATGCTGGG GAGTGTCGTC
GGAAATTGGC AGTACTTCTT TCCTGTGATC TTCAGCAAAG CTTCCGATTC CTTGCAGCTG
GTCTTTGGCA TCGAGCTGAT GGAAGTGGAC CCCATCGGCC ACGTGTACAT CTTTGCCACC
TGCCTGGGCC TCTCCTACGA TGGCCTGCTG GGTGACAATC AGATCATGCC CAAGACAGGC
TTCCTGATAA TCATCCTGGC CATAATCGCA AAAGAGGGCG ACTGTGCCCC TGAGGAGAAA
ATCTGGGAGG AGCTGAGTGT GTTAGAGGTG TTTGAGGGGA GGGAAGACAG TATCTTCGGG
GATCCCAAGA AGCTGCTCAC CCAATATTTC GTGCAGGAAA ACTACCTGGA GTACCGGCAG
GTCCCCGGCA GTGATCCTGC ATGCTATGAG TTCCTGTGGG GTCCAAGGGC CCTCATTGAA
ACCAGCTATG TGAAAGTCCT GCACCATATG GTAAAGATCA GTGGAGGACC TCGCATTTCC
TACCCACTCC TGCATGAGTG GGCTTTGAGA GAGGGGGAAG AGTGA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

 
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