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MAGEB4 cDNA ORF clone, Homo sapiens (human)

Gene Symbol MAGEB4
Entrez Gene ID 4115
Full Name melanoma antigen family B4
Synonyms CT3.6
General protein information
Preferred Names
melanoma-associated antigen B4
Names
melanoma-associated antigen B4
MAGE-B4 antigen
cancer/testis antigen family 3, member 6
Gene Type protein-coding
Organism Homo sapiens (human)
Genome

X

Xp21.3

Summary This gene is a member of the MAGEB gene family. The members of this family have their entire coding sequences located in the last exon, and the encoded proteins show 50 to 68% sequence identity to each other. The promoters and first exons of the MAGEB genes show considerable variability, suggesting that the existence of this gene family enables the same function to be expressed under different transcriptional controls. The MAGEB genes are clustered on chromosome Xp22-p21. This gene sequence ends in the first intron of MAGEB1, another family member. This gene is expressed in testis. [provided by RefSeq, Jul 2008]. COMPLETENESS: complete on the 3' end. lac of sum
Disorder MIM:

300153


mRNA and Protein(s)

mRNA Protein Name
NM_002367 NP_002358 melanoma-associated antigen B4


Homo sapiens (human) MAGEB4 NP_002358.1
Pan troglodytes (chimpanzee) MAGEB4 NP_001233531.1
Macaca mulatta (Rhesus monkey) MAGEB4 XP_001095043.1
Bos taurus (cattle) MAGEB4 NP_001070518.1
Bos taurus (cattle) LOC786960 XP_003585634.2
Bos taurus (cattle) LOC788465 XP_003585601.2
Bos taurus (cattle) LOC788278 XP_005228385.1
Bos taurus (cattle) LOC100337176 XP_002700303.2
Bos taurus (cattle) LOC786803 XP_005228380.1
Bos taurus (cattle) LOC790304 XP_005228377.1
Bos taurus (cattle) LOC618701 NP_001093193.1
Bos taurus (cattle) LOC788328 XP_003585629.1
Bos taurus (cattle) MGC133764 NP_001073841.1
Bos taurus (cattle) LOC526966 XP_005228383.1
Bos taurus (cattle) LOC101906038 XP_005228384.1
Bos taurus (cattle) LOC100337353 XP_002700316.3
Rattus norvegicus (Norway rat) Mageb1 XP_006257054.1
Rattus norvegicus (Norway rat) Mageb7 NP_001102837.1
Rattus norvegicus (Norway rat) mageb1l1 XP_006257053.1

The following MAGEB4 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the MAGEB4 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

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***CloneID RefSeq Accession Definition **Vector *Turnaround time Price (USD) Select
OHu19031 NM_002367 Homo sapiens melanoma antigen family B4 (MAGEB4), mRNA. pcDNA3.1+/C-(K)DYK or customized vector 7-9 $265.30
$379.00

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.


CloneID OHu19031
Clone ID Related Accession (Same CDS sequence) NM_002367
Accession Version NM_002367.3 Documents for ORF clone product in dufault vector
Sequence Information ORF Nucleotide Sequence (Length: 1041bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ® Seamless cloning technology
Insert Structure linear
Update Date 08-FEB-2015
Organism Homo sapiens (human)
Product melanoma-associated antigen B4
Comment REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from DB056993.1, AK313769.1 and BC032852.2. This sequence is a reference standard in the RefSeqGene project. On Oct 23, 2009 this sequence version replaced gi:29171715. COMPLETENESS: complete on the 3' end.

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
ATGCCTCGGG GTCAGAAGAG TAAGCTCCGT GCCCGTGAGA AACGCCAGCG GACCCGTGGT 
CAGACCCAGG ATCTCAAGGT TGGTCAGCCT ACTGCAGCAG AGAAAGAAGA GTCTCCTTCC
TCTTCCTCAT CTGTTTTGAG GGATACTGCC TCCAGCTCCC TTGCTTTTGG CATTCCCCAG
GAGCCTCAGA GAGAGCCACC CACCACCTCT GCTGCTGCAG CTATGTCATG CACTGGATCT
GATAAAGGCG ACGAGAGCCA AGATGAGGAA AATGCAAGTT CCTCCCAGGC CTCAACATCC
ACTGAGAGAT CACTCAAAGA TTCTCTAACC AGGAAGACGA AGATGTTAGT GCAGTTCCTG
CTGTACAAGT ATAAAATGAA AGAGCCCACT ACAAAGGCAG AAATGCTGAA GATCATCAGC
AAAAAGTACA AGGAGCACTT CCCTGAGATC TTCAGGAAAG TCTCTCAGCG CACGGAGCTG
GTCTTTGGCC TTGCCTTGAA GGAGGTCAAC CCCACCACTC ACTCCTACAT CCTCGTCAGC
ATGCTAGGCC CCAACGATGG AAACCAGAGC AGTGCCTGGA CCCTTCCAAG GAATGGGCTT
CTGATGCCTC TACTGAGTGT GATCTTCTTA AATGGCAACT GTGCCCGTGA AGAGGAAATC
TGGGAATTCC TGAATATGCT GGGGATCTAT GATGGAAAGA GGCACCTTAT CTTTGGGGAA
CCCCGAAAGC TCATCACCCA AGATCTGGTA CAGGAAAAAT ATCTGGAATA CCAGCAGGTG
CCCAACAGTG ATCCCCCACG CTATCAATTC CTGTGGGGTC CAAGAGCTCA TGCAGAAACC
AGCAAGATGA AAGTCCTGGA GTTTTTGGCC AAGGTGAATG ACACCACCCC CAATAACTTC
CCACTGCTTT ATGAAGAGGC TTTGAGAGAT GAAGAAGAGA GAGCTGGAGC CCGGCCCAGA
GTTGCAGCCA GGCGTGGCAC TACAGCCATG ACTAGTGCGT ATTCCAGGGC CACATCCAGT
AGCTCTTCCC AACCCATGTG A

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq NP_002358.1
CDS197..1237
Misc Feature(1)86..88(+)
Misc Feature(2)203..469(+)
Misc Feature(3)542..1051(+)
Exon (1)1..2254
Gene:MAGEB4
Gene Synonym:
Translation

Target ORF information:

RefSeq Version NM_002367
Organism Homo sapiens (human)
Definition Homo sapiens melanoma antigen family B4 (MAGEB4), mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
NM_002367

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
ATGCCTCGGG GTCAGAAGAG TAAGCTCCGT GCCCGTGAGA AACGCCAGCG GACCCGTGGT 
CAGACCCAGG ATCTCAAGGT TGGTCAGCCT ACTGCAGCAG AGAAAGAAGA GTCTCCTTCC
TCTTCCTCAT CTGTTTTGAG GGATACTGCC TCCAGCTCCC TTGCTTTTGG CATTCCCCAG
GAGCCTCAGA GAGAGCCACC CACCACCTCT GCTGCTGCAG CTATGTCATG CACTGGATCT
GATAAAGGCG ACGAGAGCCA AGATGAGGAA AATGCAAGTT CCTCCCAGGC CTCAACATCC
ACTGAGAGAT CACTCAAAGA TTCTCTAACC AGGAAGACGA AGATGTTAGT GCAGTTCCTG
CTGTACAAGT ATAAAATGAA AGAGCCCACT ACAAAGGCAG AAATGCTGAA GATCATCAGC
AAAAAGTACA AGGAGCACTT CCCTGAGATC TTCAGGAAAG TCTCTCAGCG CACGGAGCTG
GTCTTTGGCC TTGCCTTGAA GGAGGTCAAC CCCACCACTC ACTCCTACAT CCTCGTCAGC
ATGCTAGGCC CCAACGATGG AAACCAGAGC AGTGCCTGGA CCCTTCCAAG GAATGGGCTT
CTGATGCCTC TACTGAGTGT GATCTTCTTA AATGGCAACT GTGCCCGTGA AGAGGAAATC
TGGGAATTCC TGAATATGCT GGGGATCTAT GATGGAAAGA GGCACCTTAT CTTTGGGGAA
CCCCGAAAGC TCATCACCCA AGATCTGGTA CAGGAAAAAT ATCTGGAATA CCAGCAGGTG
CCCAACAGTG ATCCCCCACG CTATCAATTC CTGTGGGGTC CAAGAGCTCA TGCAGAAACC
AGCAAGATGA AAGTCCTGGA GTTTTTGGCC AAGGTGAATG ACACCACCCC CAATAACTTC
CCACTGCTTT ATGAAGAGGC TTTGAGAGAT GAAGAAGAGA GAGCTGGAGC CCGGCCCAGA
GTTGCAGCCA GGCGTGGCAC TACAGCCATG ACTAGTGCGT ATTCCAGGGC CACATCCAGT
AGCTCTTCCC AACCCATGTG A

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

book

The DNA sequence of the human X chromosome
Nature 434 (7031), 325-337 (2005)
Ross MT, Grafham DV, Coffey AJ, Scherer S, McLay K, Muzny D, Platzer M, Howell GR, Burrows C, Bird CP, Frankish A, Lovell FL, Howe KL, Ashurst JL, Fulton RS, Sudbrak R, Wen G, Jones MC, Hurles ME, Andrews TD, Scott CE, Searle S, Ramser J, Whittaker A, Deadman R, Carter NP, Hunt SE, Chen R, Cree A, Gunaratne P, Havlak P, Hodgson A, Metzker ML, Richards S, Scott G, Steffen D, Sodergren E, Wheeler DA, Worley KC, Ainscough R, Ambrose KD, Ansari-Lari MA, Aradhya S, Ashwell RI, Babbage AK, Bagguley CL, Ballabio A, Banerjee R, Barker GE, Barlow KF, Barrett IP, Bates KN, Beare DM, Beasley H, Beasley O, Beck A, Bethel G, Blechschmidt K, Brady N, Bray-Allen S, Bridgeman AM, Brown AJ, Brown MJ, Bonnin D, Bruford EA, Buhay C, Burch P, Burford D, Burgess J, Burrill W, Burton J, Bye JM, Carder C, Carrel L, Chako J, Chapman JC, Chavez D, Chen E, Chen G, Chen Y, Chen Z, Chinault C, Ciccodicola A, Clark SY, Clarke G, Clee CM, Clegg S, Clerc-Blankenburg K, Clifford K, Cobley V, Cole CG, Conquer JS, Corby N, Connor RE, David R, Davies J, Davis C, Davis J, Delgado O, Deshazo D, Dhami P, Ding Y, Dinh H, Dodsworth S, Draper H, Dugan-Rocha S, Dunham A, Dunn M, Durbin KJ, Dutta I, Eades T, Ellwood M, Emery-Cohen A, Errington H, Evans KL, Faulkner L, Francis F, Frankland J, Fraser AE, Galgoczy P, Gilbert J, Gill R, Glockner G, Gregory SG, Gribble S, Griffiths C, Grocock R, Gu Y, Gwilliam R, Hamilton C, Hart EA, Hawes A, Heath PD, Heitmann K, Hennig S, Hernandez J, Hinzmann B, Ho S, Hoffs M, Howden PJ, Huckle EJ, Hume J, Hunt PJ, Hunt AR, Isherwood J, Jacob L, Johnson D, Jones S, de Jong PJ, Joseph SS, Keenan S, Kelly S, Kershaw JK, Khan Z, Kioschis P, Klages S, Knights AJ, Kosiura A, Kovar-Smith C, Laird GK, Langford C, Lawlor S, Leversha M, Lewis L, Liu W, Lloyd C, Lloyd DM, Loulseged H, Loveland JE, Lovell JD, Lozado R, Lu J, Lyne R, Ma J, Maheshwari M, Matthews LH, McDowall J, McLaren S, McMurray A, Meidl P, Meitinger T, Milne S, Miner G, Mistry SL, Morgan M, Morris S, Muller I, Mullikin JC, Nguyen N, Nordsiek G, Nyakatura G, O'Dell CN, Okwuonu G, Palmer S, Pandian R, Parker D, Parrish J, Pasternak S, Patel D, Pearce AV, Pearson DM, Pelan SE, Perez L, Porter KM, Ramsey Y, Reichwald K, Rhodes S, Ridler KA, Schlessinger D, Schueler MG, Sehra HK, Shaw-Smith C, Shen H, Sheridan EM, Shownkeen R, Skuce CD, Smith ML, Sotheran EC, Steingruber HE, Steward CA, Storey R, Swann RM, Swarbreck D, Tabor PE, Taudien S, Taylor T, Teague B, Thomas K, Thorpe A, Timms K, Tracey A, Trevanion S, Tromans AC, d'Urso M, Verduzco D, Villasana D, Waldron L, Wall M, Wang Q, Warren J, Warry GL, Wei X, West A, Whitehead SL, Whiteley MN, Wilkinson JE, Willey DL, Williams G, Williams L, Williamson A, Williamson H, Wilming L, Woodmansey RL, Wray PW, Yen J, Zhang J, Zhou J, Zoghbi H, Zorilla S, Buck D, Reinhardt R, Poustka A, Rosenthal A, Lehrach H, Meindl A, Minx PJ, Hillier LW, Willard HF, Wilson RK, Waterston RH, Rice CM, Vaudin M, Coulson A, Nelson DL, Weinstock G, Sulston JE, Durbin R, Hubbard T, Gibbs RA, Beck S, Rogers J and Bentley DR.


book

Two members of the human MAGEB gene family located in Xp21.3 are expressed in tumors of various histological origins
Genomics 46 (3), 397-408 (1997)
Lurquin C, De Smet C, Brasseur F, Muscatelli F, Martelange V, De Plaen E, Brasseur R, Monaco AP and Boon T.


 
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