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MAGOH cDNA ORF clone, Homo sapiens (human)

Gene Symbol MAGOH
Entrez Gene ID 4116
Full Name mago homolog, exon junction complex core component
Synonyms MAGOH1, MAGOHA
General protein information
Preferred Names
protein mago nashi homolog
Names
protein mago nashi homolog
Gene Type protein-coding
Organism Homo sapiens (human)
Genome

1

1p32.3

Summary Drosophila that have mutations in their mago nashi (grandchildless) gene produce progeny with defects in germplasm assembly and germline development. This gene encodes the mammalian mago nashi homolog. In mammals, mRNA expression is not limited to the germ plasm, but is expressed ubiquitously in adult tissues and can be induced by serum stimulation of quiescent fibroblasts. [provided by RefSeq, Jul 2008]. lac of sum
Disorder MIM:

602603


mRNA and Protein(s)

mRNA Protein Name
NM_002370 NP_002361 protein mago nashi homolog



Homo sapiens (human) MAGOH NP_002361.1
Pan troglodytes (chimpanzee) LOC100613301 XP_003308156.1
Macaca mulatta (Rhesus monkey) MAGOH XP_001112786.1
Canis lupus familiaris (dog) MAGOH XP_536702.1
Bos taurus (cattle) MAGOH NP_001029417.1
Mus musculus (house mouse) Magoh NP_001269666.1
Rattus norvegicus (Norway rat) Magoh NP_001094006.1
Gallus gallus (chicken) MAGOH2 NP_989656.1


The following MAGOH gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the MAGOH cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID RefSeq Accession Definition **Vector *Turnaround time Price Select
OHu17496
NM_002370 Homo sapiens mago homolog, exon junction complex core component (MAGOH), mRNA. pcDNA3.1+/C-(K)DYK or customized vector
in pcDNA3.1+/C-(K)DYK
$49.50-$69.30
$99.00
Next-day Shipping ORF Clones ( in default vector with tag)
1 Clone 30% OFF
2-4 Clone 40% OFF
5 or more Clone 50% OFF
All Other ORF Clones
30% OFF

*Business Day

** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.


CloneID OHu17496
Clone ID Related Accession (Same CDS sequence) NM_002370
Accession Version NM_002370.3 Documents for ORF clone product in dufault vector
Sequence Information ORF Nucleotide Sequence (Length: 441bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags COA
ORF Insert Method CloneEZ® Seamless cloning technology
Structure linear
Update Date 15-JUL-2015
Organism Homo sapiens (human)
Product protein mago nashi homolog
Comment REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from BX283982.1, AF067173.1 and AF035940.1. On Jan 28, 2011 this sequence version replaced gi:6006021. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AF035940.1, BM808411.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END##

1
61
121
181
241
301
361
421
ATGGAGAGTG ACTTTTATCT GCGTTACTAC GTGGGGCACA AGGGCAAGTT CGGCCACGAG 
TTCCTGGAGT TTGAGTTTCG ACCGGACGGG AAGTTAAGAT ATGCCAACAA CAGCAATTAC
AAGAATGATG TCATGATCAG AAAAGAGGCT TATGTACATA AAAGCGTGAT GGAGGAACTG
AAGAGAATAA TTGACGACAG TGAAATTACC AAAGAGGATG ATGCATTGTG GCCTCCTCCT
GACCGAGTGG GCCGGCAGGA GCTTGAAATC GTCATTGGAG ATGAACACAT TTCTTTTACA
ACATCAAAAA TTGGTTCCCT TATTGATGTC AATCAATCCA AGGATCCAGA AGGCTTACGA
GTATTTTATT ATCTTGTCCA GGACCTGAAG TGTTTGGTCT TCAGTCTTAT TGGATTACAC
TTCAAGATTA AACCAATCTA G

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq NP_002361.1
CDS163..603
Misc Feature(1)61..63(+)
Misc Feature(2)163..165(+)
Misc Feature(3)172..600(+)
Misc Feature(4)193..600(+)
Misc Feature(5)193..597(+)
Misc Feature(6)199..471(+)
Misc Feature(7)202..585(+)
Misc Feature(8)247..588(+)
Misc Feature(9)358..483(+)
Exon (1)1..250
Gene:MAGOH
Gene Synonym:
Exon (2)251..309
Gene:MAGOH
Gene Synonym:
Exon (3)310..420
Gene:MAGOH
Gene Synonym:
Exon (4)421..503
Gene:MAGOH
Gene Synonym:
Exon (5)504..756
Gene:MAGOH
Gene Synonym:
Translation

Target ORF information:

RefSeq Version NM_002370
Organism Homo sapiens (human)
Definition Homo sapiens mago homolog, exon junction complex core component (MAGOH), mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
NM_002370

ORF Insert Sequence:

1
61
121
181
241
301
361
421
ATGGAGAGTG ACTTTTATCT GCGTTACTAC GTGGGGCACA AGGGCAAGTT CGGCCACGAG 
TTCCTGGAGT TTGAGTTTCG ACCGGACGGG AAGTTAAGAT ATGCCAACAA CAGCAATTAC
AAGAATGATG TCATGATCAG AAAAGAGGCT TATGTACATA AAAGCGTGAT GGAGGAACTG
AAGAGAATAA TTGACGACAG TGAAATTACC AAAGAGGATG ATGCATTGTG GCCTCCTCCT
GACCGAGTGG GCCGGCAGGA GCTTGAAATC GTCATTGGAG ATGAACACAT TTCTTTTACA
ACATCAAAAA TTGGTTCCCT TATTGATGTC AATCAATCCA AGGATCCAGA AGGCTTACGA
GTATTTTATT ATCTTGTCCA GGACCTGAAG TGTTTGGTCT TCAGTCTTAT TGGATTACAC
TTCAAGATTA AACCAATCTA G

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

book

A proteome-scale map of the human interactome network
Cell 159 (5), 1212-1226 (2014)
Rolland T, Tasan M, Charloteaux B, Pevzner SJ, Zhong Q, Sahni N, Yi S, Lemmens I, Fontanillo C, Mosca R, Kamburov A, Ghiassian SD, Yang X, Ghamsari L, Balcha D, Begg BE, Braun P, Brehme M, Broly MP, Carvunis AR, Convery-Zupan D, Corominas R, Coulombe-Huntington J, Dann E, Dreze M, Dricot A, Fan C, Franzosa E, Gebreab F, Gutierrez BJ, Hardy MF, Jin M, Kang S, Kiros R, Lin GN, Luck K, MacWilliams A, Menche J, Murray RR, Palagi A, Poulin MM, Rambout X, Rasla J, Reichert P, Romero V, Ruyssinck E, Sahalie JM, Scholz A, Shah AA, Sharma A, Shen Y, Spirohn K, Tam S, Tejeda AO, Trigg SA, Twizere JC, Vega K, Walsh J, Cusick ME, Xia Y, Barabasi AL, Iakoucheva LM, Aloy P, De Las Rivas J, Tavernier J, Calderwood MA, Hill DE, Hao T, Roth FP and Vidal M.


book

An atlas of genetic influences on human blood metabolites
Nat. Genet. 46 (6), 543-550 (2014)
Shin SY, Fauman EB, Petersen AK, Krumsiek J, Santos R, Huang J, Arnold M, Erte I, Forgetta V, Yang TP, Walter K, Menni C, Chen L, Vasquez L, Valdes AM, Hyde CL, Wang V, Ziemek D, Roberts P, Xi L, Grundberg E, Waldenberger M, Richards JB, Mohney RP, Milburn MV, John SL, Trimmer J, Theis FJ, Overington JP, Suhre K, Brosnan MJ, Gieger C, Kastenmuller G, Spector TD and Soranzo N.


book

Two mammalian MAGOH genes contribute to exon junction complex composition and nonsense-mediated decay
RNA Biol 10 (8), 1291-1298 (2013)
Singh KK, Wachsmuth L, Kulozik AE and Gehring NH.


book

Structural basis for the nuclear export activity of Importin13
EMBO J. 32 (6), 899-913 (2013)
Grunwald M, Lazzaretti D and Bono F.


book

The cellular EJC interactome reveals higher-order mRNP structure and an EJC-SR protein nexus
Cell 151 (4), 750-764 (2012)
Singh G, Kucukural A, Cenik C, Leszyk JD, Shaffer SA, Weng Z and Moore MJ.


book

Drosophila Y14 shuttles to the posterior of the oocyte and is required for oskar mRNA transport
Curr. Biol. 11 (21), 1666-1674 (2001)
Hachet O and Ephrussi A.


book

Importin 13: a novel mediator of nuclear import and export
EMBO J. 20 (14), 3685-3694 (2001)
Mingot JM, Kostka S, Kraft R, Hartmann E and Gorlich D.


book

MAGOH interacts with a novel RNA-binding protein
Genomics 63 (1), 145-148 (2000)
Zhao XF, Nowak NJ, Shows TB and Aplan PD.


book

The mammalian homologue of mago nashi encodes a serum-inducible protein
Genomics 47 (2), 319-322 (1998)
Zhao XF, Colaizzo-Anas T, Nowak NJ, Shows TB, Elliott RW and Aplan PD.


book

mago nashi mediates the posterior follicle cell-to-oocyte signal to organize axis formation in Drosophila
Development 124 (16), 3197-3207 (1997)
Newmark PA, Mohr SE, Gong L and Boswell RE.


 
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