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MBL2 cDNA ORF clone, Homo sapiens (human)

Gene Symbol MBL2
Entrez Gene ID 4153
Full Name mannose-binding lectin (protein C) 2, soluble
Synonyms COLEC1, HSMBPC, MBL, MBL2D, MBP, MBP-C, MBP1, MBPD
General protein information
Preferred Names
mannose-binding protein C
Names
mannose-binding protein C
collectin-1
mannan-binding lectin
mannose-binding lectin 2, soluble (opsonic defect)
mannose-binding lectin (protein C) 2, soluble (opsonic defect)
Gene Type protein-coding
Organism Homo sapiens (human)
Genome

10

10q11.2

Summary This gene encodes the soluble mannose-binding lectin or mannose-binding protein found in serum. The protein encoded belongs to the collectin family and is an important element in the innate immune system. The protein recognizes mannose and N-acetylglucosamine on many microorganisms, and is capable of activating the classical complement pathway. Deficiencies of this gene have been associated with susceptibility to autoimmune and infectious diseases. [provided by RefSeq, Jul 2008]. lac of sum
Disorder MIM:

154545

Disorder Html: Mannose-binding protein deficiency (3); {Diabetes mellitus,

mRNA and Protein(s)

mRNA Protein Name
XM_006717861 XP_006717924 mannose-binding protein C isoform X1
XM_011539816 XP_011538118 mannose-binding protein C isoform X1
NM_000242 NP_000233 mannose-binding protein C precursor



Homo sapiens (human) MBL2 NP_000233.1
Pan troglodytes (chimpanzee) MBL2 NP_001009005.1
Macaca mulatta (Rhesus monkey) MBL2 NP_001099005.1
Bos taurus (cattle) MBL2 NP_776532.1
Mus musculus (house mouse) Mbl2 NP_034906.1
Rattus norvegicus (Norway rat) Mbl2 NP_073195.2
Rattus norvegicus (Norway rat) LOC100911854 XP_003749136.1
Gallus gallus (chicken) MBL2 NP_989680.2
Danio rerio (zebrafish) hbl3 NP_571645.2
Danio rerio (zebrafish) hbl4 NP_001108197.1
Danio rerio (zebrafish) hbl1 XP_001341915.1
Danio rerio (zebrafish) hbl2 XP_695347.1
Xenopus (Silurana) tropicalis (western clawed frog) LOC100496214 XP_002933943.1


GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following MBL2 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the MBL2 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

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***CloneID RefSeq Accession Definition **Vector *Turnaround time Price (USD) Select
OHu19370
XM_006717861 PREDICTED: Homo sapiens mannose-binding lectin (protein C) 2, soluble (MBL2), transcript variant X1, mRNA. pcDNA3.1+/C-(K)DYK or customized vector
in pcDNA3.1+/C-(K)DYK
$49.50-$69.30
$99.00
OHu19370
XM_011539816 PREDICTED: Homo sapiens mannose-binding lectin (protein C) 2, soluble (MBL2), transcript variant X2, mRNA. pcDNA3.1+/C-(K)DYK or customized vector
in pcDNA3.1+/C-(K)DYK
$49.50-$69.30
$99.00
OHu19370
NM_000242 Homo sapiens mannose-binding lectin (protein C) 2, soluble (MBL2), mRNA. pcDNA3.1+/C-(K)DYK or customized vector
in pcDNA3.1+/C-(K)DYK
$49.50-$69.30
$99.00

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.


CloneID OHu19370
Clone ID Related Accession (Same CDS sequence) NM_000242 , XM_006717861 , XM_011539816
Accession Version XM_006717861.2 Documents for ORF clone product in dufault vector
Sequence Information ORF Nucleotide Sequence (Length: 747bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags COA
ORF Insert Method CloneEZ® Seamless cloning technology
Insert Structure linear
Update Date 12-MAR-2015
Organism Homo sapiens (human)
Product mannose-binding protein C isoform X1
Comment MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NT_030059.14) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Mar 12, 2015 this sequence version replaced gi:578819486. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Homo sapiens Annotation Release 107 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 6.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

1
61
121
181
241
301
361
421
481
541
601
661
721
ATGTCCCTGT TTCCATCACT CCCTCTCCTT CTCCTGAGTA TGGTGGCAGC GTCTTACTCA 
GAAACTGTGA CCTGTGAGGA TGCCCAAAAG ACCTGCCCTG CAGTGATTGC CTGTAGCTCT
CCAGGCATCA ACGGCTTCCC AGGCAAAGAT GGGCGTGATG GCACCAAGGG AGAAAAGGGG
GAACCAGGCC AAGGGCTCAG AGGCTTACAG GGCCCCCCTG GAAAGTTGGG GCCTCCAGGA
AATCCAGGGC CTTCTGGGTC ACCAGGACCA AAGGGCCAAA AAGGAGACCC TGGAAAAAGT
CCGGATGGTG ATAGTAGCCT GGCTGCCTCA GAAAGAAAAG CTCTGCAAAC AGAAATGGCA
CGTATCAAAA AGTGGCTCAC CTTCTCTCTG GGCAAACAAG TTGGGAACAA GTTCTTCCTG
ACCAATGGTG AAATAATGAC CTTTGAAAAA GTGAAGGCCT TGTGTGTCAA GTTCCAGGCC
TCTGTGGCCA CCCCCAGGAA TGCTGCAGAG AATGGAGCCA TTCAGAATCT CATCAAGGAG
GAAGCCTTCC TGGGCATCAC TGATGAGAAG ACAGAAGGGC AGTTTGTGGA TCTGACAGGA
AATAGACTGA CCTACACAAA CTGGAACGAG GGTGAACCCA ACAATGCTGG TTCTGATGAA
GATTGTGTAT TGCTACTGAA AAATGGCCAG TGGAATGACG TCCCCTGCTC CACCTCCCAT
CTGGCCGTCT GTGAGTTCCC TATCTGA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq XP_006717924.1
CDS128..874
Misc Feature(1)533..865(+)
Misc Feature(2)689..790(+)
Misc Feature(3)701..790(+)
Misc Feature(4)761..826(+)
Translation

Target ORF information:

RefSeq Version XM_006717861
Organism Homo sapiens (human)
Definition PREDICTED: Homo sapiens mannose-binding lectin (protein C) 2, soluble (MBL2), transcript variant X1, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
XM_006717861

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
ATGTCCCTGT TTCCATCACT CCCTCTCCTT CTCCTGAGTA TGGTGGCAGC GTCTTACTCA 
GAAACTGTGA CCTGTGAGGA TGCCCAAAAG ACCTGCCCTG CAGTGATTGC CTGTAGCTCT
CCAGGCATCA ACGGCTTCCC AGGCAAAGAT GGGCGTGATG GCACCAAGGG AGAAAAGGGG
GAACCAGGCC AAGGGCTCAG AGGCTTACAG GGCCCCCCTG GAAAGTTGGG GCCTCCAGGA
AATCCAGGGC CTTCTGGGTC ACCAGGACCA AAGGGCCAAA AAGGAGACCC TGGAAAAAGT
CCGGATGGTG ATAGTAGCCT GGCTGCCTCA GAAAGAAAAG CTCTGCAAAC AGAAATGGCA
CGTATCAAAA AGTGGCTCAC CTTCTCTCTG GGCAAACAAG TTGGGAACAA GTTCTTCCTG
ACCAATGGTG AAATAATGAC CTTTGAAAAA GTGAAGGCCT TGTGTGTCAA GTTCCAGGCC
TCTGTGGCCA CCCCCAGGAA TGCTGCAGAG AATGGAGCCA TTCAGAATCT CATCAAGGAG
GAAGCCTTCC TGGGCATCAC TGATGAGAAG ACAGAAGGGC AGTTTGTGGA TCTGACAGGA
AATAGACTGA CCTACACAAA CTGGAACGAG GGTGAACCCA ACAATGCTGG TTCTGATGAA
GATTGTGTAT TGCTACTGAA AAATGGCCAG TGGAATGACG TCCCCTGCTC CACCTCCCAT
CTGGCCGTCT GTGAGTTCCC TATCTGA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OHu19370
Clone ID Related Accession (Same CDS sequence) NM_000242 , XM_006717861 , XM_011539816
Accession Version XM_011539816.1 Documents for ORF clone product in dufault vector
Sequence Information ORF Nucleotide Sequence (Length: 747bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags COA
ORF Insert Method CloneEZ® Seamless cloning technology
Insert Structure linear
Update Date 12-MAR-2015
Organism Homo sapiens (human)
Product mannose-binding protein C isoform X1
Comment MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NT_030059.14) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Homo sapiens Annotation Release 107 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 6.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

1
61
121
181
241
301
361
421
481
541
601
661
721
ATGTCCCTGT TTCCATCACT CCCTCTCCTT CTCCTGAGTA TGGTGGCAGC GTCTTACTCA 
GAAACTGTGA CCTGTGAGGA TGCCCAAAAG ACCTGCCCTG CAGTGATTGC CTGTAGCTCT
CCAGGCATCA ACGGCTTCCC AGGCAAAGAT GGGCGTGATG GCACCAAGGG AGAAAAGGGG
GAACCAGGCC AAGGGCTCAG AGGCTTACAG GGCCCCCCTG GAAAGTTGGG GCCTCCAGGA
AATCCAGGGC CTTCTGGGTC ACCAGGACCA AAGGGCCAAA AAGGAGACCC TGGAAAAAGT
CCGGATGGTG ATAGTAGCCT GGCTGCCTCA GAAAGAAAAG CTCTGCAAAC AGAAATGGCA
CGTATCAAAA AGTGGCTCAC CTTCTCTCTG GGCAAACAAG TTGGGAACAA GTTCTTCCTG
ACCAATGGTG AAATAATGAC CTTTGAAAAA GTGAAGGCCT TGTGTGTCAA GTTCCAGGCC
TCTGTGGCCA CCCCCAGGAA TGCTGCAGAG AATGGAGCCA TTCAGAATCT CATCAAGGAG
GAAGCCTTCC TGGGCATCAC TGATGAGAAG ACAGAAGGGC AGTTTGTGGA TCTGACAGGA
AATAGACTGA CCTACACAAA CTGGAACGAG GGTGAACCCA ACAATGCTGG TTCTGATGAA
GATTGTGTAT TGCTACTGAA AAATGGCCAG TGGAATGACG TCCCCTGCTC CACCTCCCAT
CTGGCCGTCT GTGAGTTCCC TATCTGA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq XP_011538118.1
CDS115..861
Misc Feature(1)520..852(+)
Misc Feature(2)676..777(+)
Misc Feature(3)688..777(+)
Misc Feature(4)748..813(+)
Translation

Target ORF information:

RefSeq Version XM_011539816
Organism Homo sapiens (human)
Definition PREDICTED: Homo sapiens mannose-binding lectin (protein C) 2, soluble (MBL2), transcript variant X2, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
XM_011539816

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
ATGTCCCTGT TTCCATCACT CCCTCTCCTT CTCCTGAGTA TGGTGGCAGC GTCTTACTCA 
GAAACTGTGA CCTGTGAGGA TGCCCAAAAG ACCTGCCCTG CAGTGATTGC CTGTAGCTCT
CCAGGCATCA ACGGCTTCCC AGGCAAAGAT GGGCGTGATG GCACCAAGGG AGAAAAGGGG
GAACCAGGCC AAGGGCTCAG AGGCTTACAG GGCCCCCCTG GAAAGTTGGG GCCTCCAGGA
AATCCAGGGC CTTCTGGGTC ACCAGGACCA AAGGGCCAAA AAGGAGACCC TGGAAAAAGT
CCGGATGGTG ATAGTAGCCT GGCTGCCTCA GAAAGAAAAG CTCTGCAAAC AGAAATGGCA
CGTATCAAAA AGTGGCTCAC CTTCTCTCTG GGCAAACAAG TTGGGAACAA GTTCTTCCTG
ACCAATGGTG AAATAATGAC CTTTGAAAAA GTGAAGGCCT TGTGTGTCAA GTTCCAGGCC
TCTGTGGCCA CCCCCAGGAA TGCTGCAGAG AATGGAGCCA TTCAGAATCT CATCAAGGAG
GAAGCCTTCC TGGGCATCAC TGATGAGAAG ACAGAAGGGC AGTTTGTGGA TCTGACAGGA
AATAGACTGA CCTACACAAA CTGGAACGAG GGTGAACCCA ACAATGCTGG TTCTGATGAA
GATTGTGTAT TGCTACTGAA AAATGGCCAG TGGAATGACG TCCCCTGCTC CACCTCCCAT
CTGGCCGTCT GTGAGTTCCC TATCTGA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OHu19370
Clone ID Related Accession (Same CDS sequence) NM_000242 , XM_006717861 , XM_011539816
Accession Version NM_000242.2 Documents for ORF clone product in dufault vector
Sequence Information ORF Nucleotide Sequence (Length: 747bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags COA
ORF Insert Method CloneEZ® Seamless cloning technology
Insert Structure linear
Update Date 15-MAR-2015
Organism Homo sapiens (human)
Product mannose-binding protein C precursor
Comment REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AL731550.11. This sequence is a reference standard in the RefSeqGene project. On Apr 2, 2008 this sequence version replaced gi:4557738. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: X15422.1, BC069338.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2162895, SAMEA962337 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: full length.

1
61
121
181
241
301
361
421
481
541
601
661
721
ATGTCCCTGT TTCCATCACT CCCTCTCCTT CTCCTGAGTA TGGTGGCAGC GTCTTACTCA 
GAAACTGTGA CCTGTGAGGA TGCCCAAAAG ACCTGCCCTG CAGTGATTGC CTGTAGCTCT
CCAGGCATCA ACGGCTTCCC AGGCAAAGAT GGGCGTGATG GCACCAAGGG AGAAAAGGGG
GAACCAGGCC AAGGGCTCAG AGGCTTACAG GGCCCCCCTG GAAAGTTGGG GCCTCCAGGA
AATCCAGGGC CTTCTGGGTC ACCAGGACCA AAGGGCCAAA AAGGAGACCC TGGAAAAAGT
CCGGATGGTG ATAGTAGCCT GGCTGCCTCA GAAAGAAAAG CTCTGCAAAC AGAAATGGCA
CGTATCAAAA AGTGGCTCAC CTTCTCTCTG GGCAAACAAG TTGGGAACAA GTTCTTCCTG
ACCAATGGTG AAATAATGAC CTTTGAAAAA GTGAAGGCCT TGTGTGTCAA GTTCCAGGCC
TCTGTGGCCA CCCCCAGGAA TGCTGCAGAG AATGGAGCCA TTCAGAATCT CATCAAGGAG
GAAGCCTTCC TGGGCATCAC TGATGAGAAG ACAGAAGGGC AGTTTGTGGA TCTGACAGGA
AATAGACTGA CCTACACAAA CTGGAACGAG GGTGAACCCA ACAATGCTGG TTCTGATGAA
GATTGTGTAT TGCTACTGAA AAATGGCCAG TGGAATGACG TCCCCTGCTC CACCTCCCAT
CTGGCCGTCT GTGAGTTCCC TATCTGA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq NP_000233.1
CDS66..812
Misc Feature(1)18..20(+)
Misc Feature(2)204..206(+)
Misc Feature(3)282..284(+)
Misc Feature(4)300..302(+)
Misc Feature(5)309..311(+)
Misc Feature(6)327..329(+)
Misc Feature(7)471..803(+)
Misc Feature(8)627..728(+)
Misc Feature(9)639..728(+)
Misc Feature(10)699..764(+)
Exon (1)1..252
Gene:MBL2
Gene Synonym:
Exon (2)253..369
Gene:MBL2
Gene Synonym:
Exon (3)370..438
Gene:MBL2
Gene Synonym:
Exon (4)439..3569
Gene:MBL2
Gene Synonym:
Translation

Target ORF information:

RefSeq Version NM_000242
Organism Homo sapiens (human)
Definition Homo sapiens mannose-binding lectin (protein C) 2, soluble (MBL2), mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
NM_000242

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
ATGTCCCTGT TTCCATCACT CCCTCTCCTT CTCCTGAGTA TGGTGGCAGC GTCTTACTCA 
GAAACTGTGA CCTGTGAGGA TGCCCAAAAG ACCTGCCCTG CAGTGATTGC CTGTAGCTCT
CCAGGCATCA ACGGCTTCCC AGGCAAAGAT GGGCGTGATG GCACCAAGGG AGAAAAGGGG
GAACCAGGCC AAGGGCTCAG AGGCTTACAG GGCCCCCCTG GAAAGTTGGG GCCTCCAGGA
AATCCAGGGC CTTCTGGGTC ACCAGGACCA AAGGGCCAAA AAGGAGACCC TGGAAAAAGT
CCGGATGGTG ATAGTAGCCT GGCTGCCTCA GAAAGAAAAG CTCTGCAAAC AGAAATGGCA
CGTATCAAAA AGTGGCTCAC CTTCTCTCTG GGCAAACAAG TTGGGAACAA GTTCTTCCTG
ACCAATGGTG AAATAATGAC CTTTGAAAAA GTGAAGGCCT TGTGTGTCAA GTTCCAGGCC
TCTGTGGCCA CCCCCAGGAA TGCTGCAGAG AATGGAGCCA TTCAGAATCT CATCAAGGAG
GAAGCCTTCC TGGGCATCAC TGATGAGAAG ACAGAAGGGC AGTTTGTGGA TCTGACAGGA
AATAGACTGA CCTACACAAA CTGGAACGAG GGTGAACCCA ACAATGCTGG TTCTGATGAA
GATTGTGTAT TGCTACTGAA AAATGGCCAG TGGAATGACG TCCCCTGCTC CACCTCCCAT
CTGGCCGTCT GTGAGTTCCC TATCTGA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

 
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