MFAP1 cDNA ORF clone, Homo sapiens(human)
| Gene Symbol | MFAP1 |
| Entrez Gene ID | 4236 |
| Full Name | microfibril associated protein 1 |
| Synonyms | AMP |
| General protein information |
|
| Gene Type | protein-coding |
| Organism | Homo sapiens(human) |
| Genome | |
| Disorder MIM: |
mRNA and Protein(s)
| mRNA | Protein | Name |
|---|---|---|
| NM_005926.3 | NP_005917.2 | microfibrillar-associated protein 1 |
| NM_005926.2 | NP_005917.2 | microfibrillar-associated protein 1 |
| Bos taurus (cattle) | MFAP1 | NP_001029569.1 |
| Mus musculus (house mouse) | Mfap1b | NP_001075444.1 |
| Mus musculus (house mouse) | Mfap1a | NP_080496.1 |
| Rattus norvegicus (Norway rat) | Mfap1a | NP_001178893.1 |
| Drosophila melanogaster (fruit fly) | Mfap1 | NP_647679.1 |
| MFAP1 | XP_001109332.1 | |
| Oryza sativa (rice) | Os02g0280100 | NP_001046553.1 |
| Homo sapiens (human) | MFAP1 | NP_005917.2 |
| Pan troglodytes (chimpanzee) | MFAP1 | NP_001233300.1 |
| Danio rerio (zebrafish) | mfap1 | NP_957311.1 |
| Canis lupus familiaris (dog) | MFAP1 | XP_535455.2 |
| Gallus gallus (chicken) | MFAP1 | NP_001243877.1 |
| Caenorhabditis elegans (roundworm) | mfap-1 | NP_492340.1 |
| Xenopus tropicalis (tropical clawed frog) | mfap1 | NP_001011003.1 |
Related articles in PubMed
Cryo-EM Structure of a Pre-catalytic Human Spliceosome Primed for Activation.
Bertram K, Agafonov DE, Dybkov O, Haselbach D, Leelaram MN, Will CL, Urlaub H, Kastner B, L?hrmann R, Stark H
Cell170(4)701-713.e11(2017 Aug)
Human MFAP1 is a cryptic ortholog of the Saccharomyces cerevisiae Spp381 splicing factor.
Ulrich AK, Wahl MC
BMC evolutionary biology17(1)91(2017 Mar)
Insights into RNA biology from an atlas of mammalian mRNA-binding proteins.
Castello A, Fischer B, Eichelbaum K, Horos R, Beckmann BM, Strein C, Davey NE, Humphreys DT, Preiss T, Steinmetz LM, Krijgsveld J, Hentze MW
Cell149(6)1393-406(2012 Jun)
The mRNA-bound proteome and its global occupancy profile on protein-coding transcripts.
Baltz AG, Munschauer M, Schwanh?usser B, Vasile A, Murakawa Y, Schueler M, Youngs N, Penfold-Brown D, Drew K, Milek M, Wyler E, Bonneau R, Selbach M, Dieterich C, Landthaler M
Molecular cell46(5)674-90(2012 Jun)
Dynamic protein-protein interaction wiring of the human spliceosome.
Hegele A, Kamburov A, Grossmann A, Sourlis C, Wowro S, Weimann M, Will CL, Pena V, L?hrmann R, Stelzl U
Molecular cell45(4)567-80(2012 Feb)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
Study identified the human B-specific protein MFAP1 as a putative ortholog of the S. cerevisiae tri-snRNP protein Spp381. In vitro binding studies showed that human MFAP1 and yeast Spp381 bind their respective Prp38 proteins via equivalent interfaces and that they cross-interact with the Prp38 proteins of the respective other species.
Title: Human MFAP1 is a cryptic ortholog of the Saccharomyces cerevisiae Spp381 splicing factor.
Observational study of gene-disease association, gene-environment interaction, and pharmacogenomic / toxicogenomic. (HuGE Navigator)
Title: Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study.
Observational study of gene-disease association. (HuGE Navigator)
Title: Gene-centric association signals for lipids and apolipoproteins identified via the HumanCVD BeadChip.
The following MFAP1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the MFAP1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
| CloneID | OHu05238 |
|
| Clone ID Related Accession (Same CDS sequence) | NM_005926.3 , NM_005926.2 | |
| Accession Version | NM_005926.3 Latest version! | Documents for ORF clone product in default vector |
| Sequence Information | ORF Nucleotide Sequence (Length: 1320bp) Protein sequence SNP |
|
| Vector | pcDNA3.1+/C-(K)DYK or customized vector |  User Manual |
| Clone information | Clone Map | MSDS |
| Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
| ORF Insert Method | CloneEZ™ Seamless cloning technology | |
| Insert Structure | linear | |
| Update Date | 2019-05-01 | |
| Organism | Homo sapiens(human) | |
| Product | microfibrillar-associated protein 1 | |
| Comment | Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from BF981568.1, BC050742.1 and AC018512.6. On Nov 23, 2018 this sequence version replaced NM_005926.2. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR3476690.904167.1, SRR1660805.97660.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2467144, SAMEA2467146 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000267812.4/ ENSP00000267812.3 RefSeq Select criteria :: based on single protein-coding transcript ##RefSeq-Attributes-END## COMPLETENESS: full length. | |
1 | ATGTCGGTCC CAAGCGCTCT CATGAAGCAA CCGCCCATTC AGTCTACGGC TGGGGCCGTC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
| RefSeq | NP_005917.2 |
| CDS | 122..1441 |
| Translation |
Target ORF information:
Target ORF information:
|
 NM_005926.3 |
ORF Insert Sequence:
1 | ATGTCGGTCC CAAGCGCTCT CATGAAGCAA CCGCCCATTC AGTCTACGGC TGGGGCCGTC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
| CloneID | OHu05238 |
|
| Clone ID Related Accession (Same CDS sequence) | NM_005926.3 , NM_005926.2 | |
| Accession Version | NM_005926.2 | Documents for ORF clone product in default vector |
| Sequence Information | ORF Nucleotide Sequence (Length: 1320bp) Protein sequence SNP |
|
| Vector | pcDNA3.1+/C-(K)DYK or customized vector | User Manual |
| Clone information | Clone Map | MSDS |
| Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
| ORF Insert Method | CloneEZ™ Seamless cloning technology | |
| Insert Structure | linear | |
| Update Date | 2017-09-30 | |
| Organism | Homo sapiens(human) | |
| Product | microfibrillar-associated protein 1 | |
| Comment | Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from BF981568.1 and BC050742.1. On Jul 28, 2004 this sequence version replaced NM_005926.1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1803612.84827.1, SRR1803615.275669.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2467144, SAMEA2467146 [ECO:0000348] ##Evidence-Data-END## | |
1 | ATGTCGGTCC CAAGCGCTCT CATGAAGCAA CCGCCCATTC AGTCTACGGC TGGGGCCGTC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
| RefSeq | NP_005917.2 |
| CDS | 185..1504 |
| Translation |
Target ORF information:
Target ORF information:
|
NM_005926.2 |
ORF Insert Sequence:
1 | ATGTCGGTCC CAAGCGCTCT CATGAAGCAA CCGCCCATTC AGTCTACGGC TGGGGCCGTC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
 |
Cryo-EM Structure of a Pre-catalytic Human Spliceosome Primed for Activation. |
|
Human MFAP1 is a cryptic ortholog of the Saccharomyces cerevisiae Spp381 splicing factor. |
|
Insights into RNA biology from an atlas of mammalian mRNA-binding proteins. |
|
The mRNA-bound proteome and its global occupancy profile on protein-coding transcripts. |
|
Dynamic protein-protein interaction wiring of the human spliceosome. |