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NPM1 cDNA ORF clone, Homo sapiens (human)

Gene Symbol NPM1
Entrez Gene ID 4869
Full Name nucleophosmin (nucleolar phosphoprotein B23, numatrin)
Synonyms B23, NPM
General protein information
Preferred Names
nucleophosmin
Names
nucleophosmin
nucleolar protein NO38
nucleophosmin/nucleoplasmin family, member 1
Gene Type protein-coding
Organism Homo sapiens (human)
Genome

5

5q35.1

Summary This gene encodes a phosphoprotein which moves between the nucleus and the cytoplasm. The gene product is thought to be involved in several processes including regulation of the ARF/p53 pathway. A number of genes are fusion partners have been characterized, in particular the anaplastic lymphoma kinase gene on chromosome 2. Mutations in this gene are associated with acute myeloid leukemia. More than a dozen pseudogenes of this gene have been identified. Alternative splicing results in multiple transcript variants.[provided by RefSeq, Nov 2009]. lac of sum
Disorder MIM:

164040

Disorder Html: Leukemia, acute promyelocytic, NPM/RARA type (3); Leukemia, acute

mRNA and Protein(s)

mRNA Protein Name
XM_011534564 XP_011532866 nucleophosmin isoform X1
XM_005265920 XP_005265977 nucleophosmin isoform X2
NM_199185 NP_954654 nucleophosmin isoform 2
NM_001037738 NP_001032827 nucleophosmin isoform 3
NM_002520 NP_002511 nucleophosmin isoform 1



Homo sapiens (human) NPM1 NP_002511.1
Pan troglodytes (chimpanzee) NPM1 NP_001238905.1
Macaca mulatta (Rhesus monkey) LOC706883 XP_002804677.1
Canis lupus familiaris (dog) NPM1 NP_001239100.1
Bos taurus (cattle) NPM1 NP_001030518.1
Mus musculus (house mouse) Npm1 NP_032748.1
Rattus norvegicus (Norway rat) Npm1 NP_037124.1
Gallus gallus (chicken) NPM1 NP_990598.1
Danio rerio (zebrafish) npm1a NP_955460.1
Xenopus (Silurana) tropicalis (western clawed frog) npm1 NP_988883.1


GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following NPM1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the NPM1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

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***CloneID RefSeq Accession Definition **Vector *Turnaround time Price (USD) Select
OHu59316 XM_011534564 PREDICTED: Homo sapiens nucleophosmin (nucleolar phosphoprotein B23, numatrin) (NPM1), transcript variant X1, mRNA. pcDNA3.1+/C-(K)DYK or customized vector TBD $139.30
$199.00
OHu40015 XM_005265920 PREDICTED: Homo sapiens nucleophosmin (nucleolar phosphoprotein B23, numatrin) (NPM1), transcript variant X2, mRNA. pcDNA3.1+/C-(K)DYK or customized vector 7-9 $139.30
$199.00
OHu15843
NM_199185 Homo sapiens nucleophosmin (nucleolar phosphoprotein B23, numatrin) (NPM1), transcript variant 2, mRNA. pcDNA3.1+/C-(K)DYK or customized vector
in pcDNA3.1+/C-(K)DYK
$49.50-$69.30
$99.00
OHu15781
NM_001037738 Homo sapiens nucleophosmin (nucleolar phosphoprotein B23, numatrin) (NPM1), transcript variant 3, mRNA. pcDNA3.1+/C-(K)DYK or customized vector
in pcDNA3.1+/C-(K)DYK
$49.50-$69.30
$99.00
OHu21782
NM_002520 Homo sapiens nucleophosmin (nucleolar phosphoprotein B23, numatrin) (NPM1), transcript variant 1, mRNA. pcDNA3.1+/C-(K)DYK or customized vector
in pcDNA3.1+/C-(K)DYK
$154.50-$216.30
$309.00

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.


CloneID OHu59316
Clone ID Related Accession (Same CDS sequence) XM_011534564
Accession Version XM_011534564.1 Documents for ORF clone product in dufault vector
Sequence Information ORF Nucleotide Sequence (Length: 693bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ® Seamless cloning technology
Insert Structure linear
Update Date 12-MAR-2015
Organism Homo sapiens (human)
Product nucleophosmin isoform X1
Comment MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NT_023133.14) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Homo sapiens Annotation Release 107 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 6.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

1
61
121
181
241
301
361
421
481
541
601
661
ATGAATTACG AAGGCAGTCC AATTAAAGTA ACACTGGCAA CTTTGAAAAT GTCTGTACAG 
CCAACGGTTT CCCTTGGGGG CTTTGAAATA ACACCACCAG TGGTCTTAAG GTTGAAGTGT
GGTTCAGGGC CAGTGCATAT TAGTGGACAG CACTTAGTAG CTGTGGAGGA AGATGCAGAG
TCAGAAGATG AAGAGGAGGA GGATGTGAAA CTCTTAAGTA TATCTGGAAA GCGGTCTGCC
CCTGGAGGTG GTAGCAAGGT TCCACAGAAA AAAGTAAAAC TTGCTGCTGA TGAAGATGAT
GACGATGATG ATGAAGAGGA TGATGATGAA GATGATGATG ATGATGATTT TGATGATGAG
GAAGCTGAAG AAAAAGCGCC AGTGAAGAAA TCTATACGAG ATACTCCAGC CAAAAATGCA
CAAAAGTCAA ATCAGAATGG AAAAGACTCA AAACCATCAT CAACACCAAG ATCAAAAGGA
CAAGAATCCT TCAAGAAACA GGAAAAAACT CCTAAAACAC CAAAAGGACC TAGTTCTGTA
GAAGACATTA AAGCAAAAAT GCAAGCAAGT ATAGAAAAAG GTGGTTCTCT TCCCAAAGTG
GAAGCCAAAT TCATCAATTA TGTGAAGAAT TGCTTCCGGA TGACTGACCA AGAGGCTATT
CAAGATCTCT GGCAGTGGAG GAAGTCTCTT TAA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq XP_011532866.1
CDS258..950
Misc Feature(1)258..>422(+)
Translation

Target ORF information:

RefSeq Version XM_011534564
Organism Homo sapiens (human)
Definition PREDICTED: Homo sapiens nucleophosmin (nucleolar phosphoprotein B23, numatrin) (NPM1), transcript variant X1, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
XM_011534564

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
ATGAATTACG AAGGCAGTCC AATTAAAGTA ACACTGGCAA CTTTGAAAAT GTCTGTACAG 
CCAACGGTTT CCCTTGGGGG CTTTGAAATA ACACCACCAG TGGTCTTAAG GTTGAAGTGT
GGTTCAGGGC CAGTGCATAT TAGTGGACAG CACTTAGTAG CTGTGGAGGA AGATGCAGAG
TCAGAAGATG AAGAGGAGGA GGATGTGAAA CTCTTAAGTA TATCTGGAAA GCGGTCTGCC
CCTGGAGGTG GTAGCAAGGT TCCACAGAAA AAAGTAAAAC TTGCTGCTGA TGAAGATGAT
GACGATGATG ATGAAGAGGA TGATGATGAA GATGATGATG ATGATGATTT TGATGATGAG
GAAGCTGAAG AAAAAGCGCC AGTGAAGAAA TCTATACGAG ATACTCCAGC CAAAAATGCA
CAAAAGTCAA ATCAGAATGG AAAAGACTCA AAACCATCAT CAACACCAAG ATCAAAAGGA
CAAGAATCCT TCAAGAAACA GGAAAAAACT CCTAAAACAC CAAAAGGACC TAGTTCTGTA
GAAGACATTA AAGCAAAAAT GCAAGCAAGT ATAGAAAAAG GTGGTTCTCT TCCCAAAGTG
GAAGCCAAAT TCATCAATTA TGTGAAGAAT TGCTTCCGGA TGACTGACCA AGAGGCTATT
CAAGATCTCT GGCAGTGGAG GAAGTCTCTT TAA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OHu40015
Clone ID Related Accession (Same CDS sequence) XM_005265920
Accession Version XM_005265920.2 Documents for ORF clone product in dufault vector
Sequence Information ORF Nucleotide Sequence (Length: 693bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ® Seamless cloning technology
Insert Structure linear
Update Date 12-MAR-2015
Organism Homo sapiens (human)
Product nucleophosmin isoform X2
Comment MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NT_023133.14) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Mar 12, 2015 this sequence version replaced gi:530381065. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Homo sapiens Annotation Release 107 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 6.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

1
61
121
181
241
301
361
421
481
541
601
661
ATGGAAGATT CGATGGACAT GGACATGAGC CCCCTGAGGC CCCAGAACTA TCTTTTCGGT 
TGTGAACTAA AGGCCGACAA AGATTATCAC TTTAAGGTGG ATAATGATGA AAATGAGCAC
CAGTTATCTT TAAGAACGGT CAGTTTAGGG GCTGGTGCAA AGGATGAGTT GCACATTGTT
GAAGCAGAGG CAATGAATTA CGAAGGCAGT CCAATTAAAG TAACACTGGC AACTTTGAAA
ATGTCTGTAC AGCCAACGGT TTCCCTTGGG GGCTTTGAAA TAACACCACC AGTGGTCTTA
AGGTTGAAGT GTGGTTCAGG GCCAGTGCAT ATTAGTGGAC AGCACTTAGT AGCTGTGGAG
GAAGATGCAG AGTCAGAAGA TGAAGAGGAG GAGGATGTGA AACTCTTAAG TATATCTGGA
AAGCGGTCTG CCCCTGGAGG TGGTAGCAAG GTTCCACAGA AAAAAGTAAA ACTTGCTGCT
GATGAAGATG ATGACGATGA TGATGAAGAG GATGATGATG AAGATGATGA TGATGATGAT
TTTGATGATG AGGAAGCTGA AGAAAAAGCG CCAGTGAAGA AAGGACAAGA ATCCTTCAAG
AAACAGGAAA AAACTCCTAA AACACCAAAA GGACCTAGTT CTGTAGAAGA CATTAAAGCA
AAAATGCAAG CAAGTATAGA AAAAGCGCAT TGA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq XP_005265977.1
CDS302..994
Misc Feature(1)338..>658(+)
Translation

Target ORF information:

RefSeq Version XM_005265920
Organism Homo sapiens (human)
Definition PREDICTED: Homo sapiens nucleophosmin (nucleolar phosphoprotein B23, numatrin) (NPM1), transcript variant X2, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
XM_005265920

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
ATGGAAGATT CGATGGACAT GGACATGAGC CCCCTGAGGC CCCAGAACTA TCTTTTCGGT 
TGTGAACTAA AGGCCGACAA AGATTATCAC TTTAAGGTGG ATAATGATGA AAATGAGCAC
CAGTTATCTT TAAGAACGGT CAGTTTAGGG GCTGGTGCAA AGGATGAGTT GCACATTGTT
GAAGCAGAGG CAATGAATTA CGAAGGCAGT CCAATTAAAG TAACACTGGC AACTTTGAAA
ATGTCTGTAC AGCCAACGGT TTCCCTTGGG GGCTTTGAAA TAACACCACC AGTGGTCTTA
AGGTTGAAGT GTGGTTCAGG GCCAGTGCAT ATTAGTGGAC AGCACTTAGT AGCTGTGGAG
GAAGATGCAG AGTCAGAAGA TGAAGAGGAG GAGGATGTGA AACTCTTAAG TATATCTGGA
AAGCGGTCTG CCCCTGGAGG TGGTAGCAAG GTTCCACAGA AAAAAGTAAA ACTTGCTGCT
GATGAAGATG ATGACGATGA TGATGAAGAG GATGATGATG AAGATGATGA TGATGATGAT
TTTGATGATG AGGAAGCTGA AGAAAAAGCG CCAGTGAAGA AAGGACAAGA ATCCTTCAAG
AAACAGGAAA AAACTCCTAA AACACCAAAA GGACCTAGTT CTGTAGAAGA CATTAAAGCA
AAAATGCAAG CAAGTATAGA AAAAGCGCAT TGA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OHu15843
Clone ID Related Accession (Same CDS sequence) NM_199185
Accession Version NM_199185.3 Documents for ORF clone product in dufault vector
Sequence Information ORF Nucleotide Sequence (Length: 798bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags COA
ORF Insert Method CloneEZ® Seamless cloning technology
Insert Structure linear
Update Date 15-MAR-2015
Organism Homo sapiens (human)
Product nucleophosmin isoform 2
Comment REVIEWED REFSEQ: This record has been curated by NCBI staff in collaboration with Francesco Amaldi. The reference sequence was derived from AC091980.4, BC009623.2 and AC093246.3. On Nov 3, 2009 this sequence version replaced gi:83641867. Transcript Variant: This variant (2) lacks an alternate in-frame exon, compared to variant 1, resulting in a shorter protein (isoform 2) that lacks an internal segment, compared to isoform 1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC009623.2, AL537010.3 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: full length.

1
61
121
181
241
301
361
421
481
541
601
661
721
781
ATGGAAGATT CGATGGACAT GGACATGAGC CCCCTGAGGC CCCAGAACTA TCTTTTCGGT 
TGTGAACTAA AGGCCGACAA AGATTATCAC TTTAAGGTGG ATAATGATGA AAATGAGCAC
CAGTTATCTT TAAGAACGGT CAGTTTAGGG GCTGGTGCAA AGGATGAGTT GCACATTGTT
GAAGCAGAGG CAATGAATTA CGAAGGCAGT CCAATTAAAG TAACACTGGC AACTTTGAAA
ATGTCTGTAC AGCCAACGGT TTCCCTTGGG GGCTTTGAAA TAACACCACC AGTGGTCTTA
AGGTTGAAGT GTGGTTCAGG GCCAGTGCAT ATTAGTGGAC AGCACTTAGT AGCTGTGGAG
GAAGATGCAG AGTCAGAAGA TGAAGAGGAG GAGGATGTGA AACTCTTAAG TATATCTGGA
AAGCGGTCTG CCCCTGGAGG TGGTAGCAAG GTTCCACAGA AAAAAGTAAA ACTTGCTGCT
GATGAAGATG ATGACGATGA TGATGAAGAG GATGATGATG AAGATGATGA TGATGATGAT
TTTGATGATG AGGAAGCTGA AGAAAAAGCG CCAGTGAAGA AAGGACAAGA ATCCTTCAAG
AAACAGGAAA AAACTCCTAA AACACCAAAA GGACCTAGTT CTGTAGAAGA CATTAAAGCA
AAAATGCAAG CAAGTATAGA AAAAGGTGGT TCTCTTCCCA AAGTGGAAGC CAAATTCATC
AATTATGTGA AGAATTGCTT CCGGATGACT GACCAAGAGG CTATTCAAGA TCTCTGGCAG
TGGAGGAAGT CTCTTTAA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq NP_954654.1
CDS246..1043
Misc Feature(1)255..257(+)
Misc Feature(2)273..275(+)
Misc Feature(3)282..>602(+)
Misc Feature(4)444..446(+)
Misc Feature(5)453..455(+)
Misc Feature(6)453..455(+)
Misc Feature(7)528..530(+)
Misc Feature(8)618..620(+)
Misc Feature(9)618..620(+)
Misc Feature(10)858..860(+)
Misc Feature(11)867..869(+)
Misc Feature(12)918..920(+)
Misc Feature(13)918..920(+)
Exon (1)1..303
Gene:NPM1
Gene Synonym:
Exon (2)304..383
Gene:NPM1
Gene Synonym:
Exon (3)384..503
Gene:NPM1
Gene Synonym:
Exon (4)504..597
Gene:NPM1
Gene Synonym:
Exon (5)598..704
Gene:NPM1
Gene Synonym:
Exon (6)705..769
Gene:NPM1
Gene Synonym:
Exon (7)770..827
Gene:NPM1
Gene Synonym:
Exon (8)828..929
Gene:NPM1
Gene Synonym:
Exon (9)930..1004
Gene:NPM1
Gene Synonym:
Exon (10)1005..1362
Gene:NPM1
Gene Synonym:
Translation

Target ORF information:

RefSeq Version NM_199185
Organism Homo sapiens (human)
Definition Homo sapiens nucleophosmin (nucleolar phosphoprotein B23, numatrin) (NPM1), transcript variant 2, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
NM_199185

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
ATGGAAGATT CGATGGACAT GGACATGAGC CCCCTGAGGC CCCAGAACTA TCTTTTCGGT 
TGTGAACTAA AGGCCGACAA AGATTATCAC TTTAAGGTGG ATAATGATGA AAATGAGCAC
CAGTTATCTT TAAGAACGGT CAGTTTAGGG GCTGGTGCAA AGGATGAGTT GCACATTGTT
GAAGCAGAGG CAATGAATTA CGAAGGCAGT CCAATTAAAG TAACACTGGC AACTTTGAAA
ATGTCTGTAC AGCCAACGGT TTCCCTTGGG GGCTTTGAAA TAACACCACC AGTGGTCTTA
AGGTTGAAGT GTGGTTCAGG GCCAGTGCAT ATTAGTGGAC AGCACTTAGT AGCTGTGGAG
GAAGATGCAG AGTCAGAAGA TGAAGAGGAG GAGGATGTGA AACTCTTAAG TATATCTGGA
AAGCGGTCTG CCCCTGGAGG TGGTAGCAAG GTTCCACAGA AAAAAGTAAA ACTTGCTGCT
GATGAAGATG ATGACGATGA TGATGAAGAG GATGATGATG AAGATGATGA TGATGATGAT
TTTGATGATG AGGAAGCTGA AGAAAAAGCG CCAGTGAAGA AAGGACAAGA ATCCTTCAAG
AAACAGGAAA AAACTCCTAA AACACCAAAA GGACCTAGTT CTGTAGAAGA CATTAAAGCA
AAAATGCAAG CAAGTATAGA AAAAGGTGGT TCTCTTCCCA AAGTGGAAGC CAAATTCATC
AATTATGTGA AGAATTGCTT CCGGATGACT GACCAAGAGG CTATTCAAGA TCTCTGGCAG
TGGAGGAAGT CTCTTTAA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OHu15781
Clone ID Related Accession (Same CDS sequence) NM_001037738
Accession Version NM_001037738.2 Documents for ORF clone product in dufault vector
Sequence Information ORF Nucleotide Sequence (Length: 780bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags COA
ORF Insert Method CloneEZ® Seamless cloning technology
Insert Structure linear
Update Date 15-MAR-2015
Organism Homo sapiens (human)
Product nucleophosmin isoform 3
Comment REVIEWED REFSEQ: This record has been curated by NCBI staff in collaboration with Francesco Amaldi. The reference sequence was derived from AC091980.4 and BC107754.1. On Nov 3, 2009 this sequence version replaced gi:83641869. Transcript Variant: This variant (3) utilizes an alternate 3'-terminal exon, compared to variant 1, resulting in a shorter protein (isoform 3) with a distinct C-terminus. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC107754.1, BX438353.2 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: full length.

1
61
121
181
241
301
361
421
481
541
601
661
721
ATGGAAGATT CGATGGACAT GGACATGAGC CCCCTGAGGC CCCAGAACTA TCTTTTCGGT 
TGTGAACTAA AGGCCGACAA AGATTATCAC TTTAAGGTGG ATAATGATGA AAATGAGCAC
CAGTTATCTT TAAGAACGGT CAGTTTAGGG GCTGGTGCAA AGGATGAGTT GCACATTGTT
GAAGCAGAGG CAATGAATTA CGAAGGCAGT CCAATTAAAG TAACACTGGC AACTTTGAAA
ATGTCTGTAC AGCCAACGGT TTCCCTTGGG GGCTTTGAAA TAACACCACC AGTGGTCTTA
AGGTTGAAGT GTGGTTCAGG GCCAGTGCAT ATTAGTGGAC AGCACTTAGT AGCTGTGGAG
GAAGATGCAG AGTCAGAAGA TGAAGAGGAG GAGGATGTGA AACTCTTAAG TATATCTGGA
AAGCGGTCTG CCCCTGGAGG TGGTAGCAAG GTTCCACAGA AAAAAGTAAA ACTTGCTGCT
GATGAAGATG ATGACGATGA TGATGAAGAG GATGATGATG AAGATGATGA TGATGATGAT
TTTGATGATG AGGAAGCTGA AGAAAAAGCG CCAGTGAAGA AATCTATACG AGATACTCCA
GCCAAAAATG CACAAAAGTC AAATCAGAAT GGAAAAGACT CAAAACCATC ATCAACACCA
AGATCAAAAG GACAAGAATC CTTCAAGAAA CAGGAAAAAA CTCCTAAAAC ACCAAAAGGA
CCTAGTTCTG TAGAAGACAT TAAAGCAAAA ATGCAAGCAA GTATAGAAAA AGCGCATTGA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq NP_001032827.1
CDS246..1025
Misc Feature(1)246..803(+)
Misc Feature(2)246..596(+)
Misc Feature(3)246..248(+)
Misc Feature(4)255..257(+)
Misc Feature(5)255..257(+)
Misc Feature(6)273..275(+)
Misc Feature(7)273..275(+)
Misc Feature(8)282..>602(+)
Misc Feature(9)339..341(+)
Misc Feature(10)408..410(+)
Misc Feature(11)444..446(+)
Misc Feature(12)453..455(+)
Misc Feature(13)453..455(+)
Misc Feature(14)468..470(+)
Misc Feature(15)483..485(+)
Misc Feature(16)528..530(+)
Misc Feature(17)528..530(+)
Misc Feature(18)618..620(+)
Misc Feature(19)618..620(+)
Misc Feature(20)654..656(+)
Misc Feature(21)660..662(+)
Misc Feature(22)693..695(+)
Misc Feature(23)699..716(+)
Misc Feature(24)705..707(+)
Misc Feature(25)768..773(+)
Misc Feature(26)816..836(+)
Misc Feature(27)840..842(+)
Misc Feature(28)879..881(+)
Misc Feature(29)900..902(+)
Misc Feature(30)924..926(+)
Misc Feature(31)930..932(+)
Misc Feature(32)933..935(+)
Misc Feature(33)945..947(+)
Misc Feature(34)954..956(+)
Misc Feature(35)969..971(+)
Misc Feature(36)972..974(+)
Misc Feature(37)993..995(+)
Misc Feature(38)1005..1007(+)
Misc Feature(39)1005..1007(+)
Misc Feature(40)1014..1016(+)
Exon (1)1..303
Gene:NPM1
Gene Synonym:
Exon (2)304..383
Gene:NPM1
Gene Synonym:
Exon (3)384..503
Gene:NPM1
Gene Synonym:
Exon (4)504..597
Gene:NPM1
Gene Synonym:
Exon (5)598..704
Gene:NPM1
Gene Synonym:
Exon (6)705..769
Gene:NPM1
Gene Synonym:
Exon (7)770..827
Gene:NPM1
Gene Synonym:
Exon (8)828..914
Gene:NPM1
Gene Synonym:
Exon (9)915..1016
Gene:NPM1
Gene Synonym:
Exon (10)1017..1347
Gene:NPM1
Gene Synonym:
Translation

Target ORF information:

RefSeq Version NM_001037738
Organism Homo sapiens (human)
Definition Homo sapiens nucleophosmin (nucleolar phosphoprotein B23, numatrin) (NPM1), transcript variant 3, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
NM_001037738

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
ATGGAAGATT CGATGGACAT GGACATGAGC CCCCTGAGGC CCCAGAACTA TCTTTTCGGT 
TGTGAACTAA AGGCCGACAA AGATTATCAC TTTAAGGTGG ATAATGATGA AAATGAGCAC
CAGTTATCTT TAAGAACGGT CAGTTTAGGG GCTGGTGCAA AGGATGAGTT GCACATTGTT
GAAGCAGAGG CAATGAATTA CGAAGGCAGT CCAATTAAAG TAACACTGGC AACTTTGAAA
ATGTCTGTAC AGCCAACGGT TTCCCTTGGG GGCTTTGAAA TAACACCACC AGTGGTCTTA
AGGTTGAAGT GTGGTTCAGG GCCAGTGCAT ATTAGTGGAC AGCACTTAGT AGCTGTGGAG
GAAGATGCAG AGTCAGAAGA TGAAGAGGAG GAGGATGTGA AACTCTTAAG TATATCTGGA
AAGCGGTCTG CCCCTGGAGG TGGTAGCAAG GTTCCACAGA AAAAAGTAAA ACTTGCTGCT
GATGAAGATG ATGACGATGA TGATGAAGAG GATGATGATG AAGATGATGA TGATGATGAT
TTTGATGATG AGGAAGCTGA AGAAAAAGCG CCAGTGAAGA AATCTATACG AGATACTCCA
GCCAAAAATG CACAAAAGTC AAATCAGAAT GGAAAAGACT CAAAACCATC ATCAACACCA
AGATCAAAAG GACAAGAATC CTTCAAGAAA CAGGAAAAAA CTCCTAAAAC ACCAAAAGGA
CCTAGTTCTG TAGAAGACAT TAAAGCAAAA ATGCAAGCAA GTATAGAAAA AGCGCATTGA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OHu21782
Clone ID Related Accession (Same CDS sequence) NM_002520
Accession Version NM_002520.6 Documents for ORF clone product in dufault vector
Sequence Information ORF Nucleotide Sequence (Length: 885bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags COA
ORF Insert Method CloneEZ® Seamless cloning technology
Insert Structure linear
Update Date 15-MAR-2015
Organism Homo sapiens (human)
Product nucleophosmin isoform 1
Comment REVIEWED REFSEQ: This record has been curated by NCBI staff in collaboration with Francesco Amaldi. The reference sequence was derived from AC091980.4 and BC002398.2. This sequence is a reference standard in the RefSeqGene project. On Nov 3, 2009 this sequence version replaced gi:83641868. Transcript Variant: This predominant variant (1) represents the longest transcript and encodes the longest isoform (1). Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: DQ303464.1, BC008495.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: full length.

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
ATGGAAGATT CGATGGACAT GGACATGAGC CCCCTGAGGC CCCAGAACTA TCTTTTCGGT 
TGTGAACTAA AGGCCGACAA AGATTATCAC TTTAAGGTGG ATAATGATGA AAATGAGCAC
CAGTTATCTT TAAGAACGGT CAGTTTAGGG GCTGGTGCAA AGGATGAGTT GCACATTGTT
GAAGCAGAGG CAATGAATTA CGAAGGCAGT CCAATTAAAG TAACACTGGC AACTTTGAAA
ATGTCTGTAC AGCCAACGGT TTCCCTTGGG GGCTTTGAAA TAACACCACC AGTGGTCTTA
AGGTTGAAGT GTGGTTCAGG GCCAGTGCAT ATTAGTGGAC AGCACTTAGT AGCTGTGGAG
GAAGATGCAG AGTCAGAAGA TGAAGAGGAG GAGGATGTGA AACTCTTAAG TATATCTGGA
AAGCGGTCTG CCCCTGGAGG TGGTAGCAAG GTTCCACAGA AAAAAGTAAA ACTTGCTGCT
GATGAAGATG ATGACGATGA TGATGAAGAG GATGATGATG AAGATGATGA TGATGATGAT
TTTGATGATG AGGAAGCTGA AGAAAAAGCG CCAGTGAAGA AATCTATACG AGATACTCCA
GCCAAAAATG CACAAAAGTC AAATCAGAAT GGAAAAGACT CAAAACCATC ATCAACACCA
AGATCAAAAG GACAAGAATC CTTCAAGAAA CAGGAAAAAA CTCCTAAAAC ACCAAAAGGA
CCTAGTTCTG TAGAAGACAT TAAAGCAAAA ATGCAAGCAA GTATAGAAAA AGGTGGTTCT
CTTCCCAAAG TGGAAGCCAA ATTCATCAAT TATGTGAAGA ATTGCTTCCG GATGACTGAC
CAAGAGGCTA TTCAAGATCT CTGGCAGTGG AGGAAGTCTC TTTAA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq NP_002511.1
CDS246..1130
Misc Feature(1)246..803(+)
Misc Feature(2)246..596(+)
Misc Feature(3)246..248(+)
Misc Feature(4)255..257(+)
Misc Feature(5)255..257(+)
Misc Feature(6)273..275(+)
Misc Feature(7)273..275(+)
Misc Feature(8)282..>602(+)
Misc Feature(9)339..341(+)
Misc Feature(10)408..410(+)
Misc Feature(11)444..446(+)
Misc Feature(12)453..455(+)
Misc Feature(13)453..455(+)
Misc Feature(14)453..455(+)
Misc Feature(15)468..470(+)
Misc Feature(16)483..485(+)
Misc Feature(17)528..530(+)
Misc Feature(18)528..530(+)
Misc Feature(19)618..620(+)
Misc Feature(20)618..620(+)
Misc Feature(21)618..620(+)
Misc Feature(22)654..656(+)
Misc Feature(23)660..662(+)
Misc Feature(24)693..695(+)
Misc Feature(25)699..716(+)
Misc Feature(26)705..707(+)
Misc Feature(27)768..773(+)
Misc Feature(28)816..836(+)
Misc Feature(29)840..842(+)
Misc Feature(30)840..842(+)
Misc Feature(31)879..881(+)
Misc Feature(32)900..902(+)
Misc Feature(33)900..902(+)
Misc Feature(34)924..926(+)
Misc Feature(35)930..932(+)
Misc Feature(36)933..935(+)
Misc Feature(37)945..947(+)
Misc Feature(38)945..947(+)
Misc Feature(39)954..956(+)
Misc Feature(40)954..956(+)
Misc Feature(41)969..971(+)
Misc Feature(42)972..1127(+)
Misc Feature(43)972..974(+)
Misc Feature(44)993..995(+)
Misc Feature(45)1005..1007(+)
Misc Feature(46)1005..1007(+)
Misc Feature(47)1005..1007(+)
Misc Feature(48)1014..1016(+)
Misc Feature(49)1023..1025(+)
Misc Feature(50)1044..1046(+)
Misc Feature(51)1062..1064(+)
Misc Feature(52)1080..1082(+)
Misc Feature(53)1119..1121(+)
Exon (1)1..303
Gene:NPM1
Gene Synonym:
Exon (2)304..383
Gene:NPM1
Gene Synonym:
Exon (3)384..503
Gene:NPM1
Gene Synonym:
Exon (4)504..597
Gene:NPM1
Gene Synonym:
Exon (5)598..704
Gene:NPM1
Gene Synonym:
Exon (6)705..769
Gene:NPM1
Gene Synonym:
Exon (7)770..827
Gene:NPM1
Gene Synonym:
Exon (8)828..914
Gene:NPM1
Gene Synonym:
Exon (9)915..1016
Gene:NPM1
Gene Synonym:
Exon (10)1017..1091
Gene:NPM1
Gene Synonym:
Exon (11)1092..1449
Gene:NPM1
Gene Synonym:
Translation

Target ORF information:

RefSeq Version NM_002520
Organism Homo sapiens (human)
Definition Homo sapiens nucleophosmin (nucleolar phosphoprotein B23, numatrin) (NPM1), transcript variant 1, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
NM_002520

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
ATGGAAGATT CGATGGACAT GGACATGAGC CCCCTGAGGC CCCAGAACTA TCTTTTCGGT 
TGTGAACTAA AGGCCGACAA AGATTATCAC TTTAAGGTGG ATAATGATGA AAATGAGCAC
CAGTTATCTT TAAGAACGGT CAGTTTAGGG GCTGGTGCAA AGGATGAGTT GCACATTGTT
GAAGCAGAGG CAATGAATTA CGAAGGCAGT CCAATTAAAG TAACACTGGC AACTTTGAAA
ATGTCTGTAC AGCCAACGGT TTCCCTTGGG GGCTTTGAAA TAACACCACC AGTGGTCTTA
AGGTTGAAGT GTGGTTCAGG GCCAGTGCAT ATTAGTGGAC AGCACTTAGT AGCTGTGGAG
GAAGATGCAG AGTCAGAAGA TGAAGAGGAG GAGGATGTGA AACTCTTAAG TATATCTGGA
AAGCGGTCTG CCCCTGGAGG TGGTAGCAAG GTTCCACAGA AAAAAGTAAA ACTTGCTGCT
GATGAAGATG ATGACGATGA TGATGAAGAG GATGATGATG AAGATGATGA TGATGATGAT
TTTGATGATG AGGAAGCTGA AGAAAAAGCG CCAGTGAAGA AATCTATACG AGATACTCCA
GCCAAAAATG CACAAAAGTC AAATCAGAAT GGAAAAGACT CAAAACCATC ATCAACACCA
AGATCAAAAG GACAAGAATC CTTCAAGAAA CAGGAAAAAA CTCCTAAAAC ACCAAAAGGA
CCTAGTTCTG TAGAAGACAT TAAAGCAAAA ATGCAAGCAA GTATAGAAAA AGGTGGTTCT
CTTCCCAAAG TGGAAGCCAA ATTCATCAAT TATGTGAAGA ATTGCTTCCG GATGACTGAC
CAAGAGGCTA TTCAAGATCT CTGGCAGTGG AGGAAGTCTC TTTAA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

 
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