×

GPR143 cDNA ORF clone, Homo sapiens (human)

Gene Symbol GPR143
Entrez Gene ID 4935
Full Name G protein-coupled receptor 143
Synonyms NYS6, OA1
General protein information
Preferred Names
G-protein coupled receptor 143
Names
G-protein coupled receptor 143
ocular albinism type 1 protein
Gene Type protein-coding
Organism Homo sapiens (human)
Genome

X

Xp22.3

Summary This gene encodes a protein that binds to heterotrimeric G proteins and is targeted to melanosomes in pigment cells. This protein is thought to be involved in intracellular signal transduction mechanisms. Mutations in this gene cause ocular albinism type 1, also referred to as Nettleship-Falls type ocular albinism, a severe visual disorder. A related pseudogene has been identified on chromosome Y. [provided by RefSeq, Dec 2009]. lac of sum
Disorder MIM:

300808

Disorder Html: Ocular albinism, type I, Nettleship-Falls type, 300500 (3);

mRNA and Protein(s)

mRNA Protein Name
XM_005274541 XP_005274598 G-protein coupled receptor 143 isoform X1
NM_000273 NP_000264 G-protein coupled receptor 143



Homo sapiens (human) GPR143 NP_000264.2
Macaca mulatta (Rhesus monkey) GPR143 XP_001090139.1
Canis lupus familiaris (dog) GPR143 XP_005642124.1
Bos taurus (cattle) GPR143 XP_002700505.1
Mus musculus (house mouse) Gpr143 NP_035081.3
Rattus norvegicus (Norway rat) Gpr143 NP_001100428.1
Gallus gallus (chicken) GPR143 NP_001264668.1
Danio rerio (zebrafish) gpr143 XP_005169192.1
Xenopus (Silurana) tropicalis (western clawed frog) gpr143 NP_001011018.1


GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following GPR143 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the GPR143 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

Free ORF Clone
for Every Scientist
More Detail >>

***CloneID RefSeq Accession Definition **Vector *Turnaround time Price (USD) Select
OHu53925 XM_005274541 PREDICTED: Homo sapiens G protein-coupled receptor 143 (GPR143), transcript variant X1, mRNA. pcDNA3.1+/C-(K)DYK or customized vector TBD $223.30
$319.00
OHu18715 NM_000273 Homo sapiens G protein-coupled receptor 143 (GPR143), mRNA. pcDNA3.1+/C-(K)DYK or customized vector TBD $223.30
$319.00

ORF Online Only Promotion

Next-day Shipping ORF Clones ( in default vector with tag)
1 Clone 30% OFF
2-4 Clone 40% OFF
5 or more Clone 50% OFF
All Other ORF Clones
30% OFF

*Business Day

** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.


CloneID OHu53925
Clone ID Related Accession (Same CDS sequence) XM_005274541
Accession Version XM_005274541.2 Documents for ORF clone product in dufault vector
Sequence Information ORF Nucleotide Sequence (Length: 1161bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ® Seamless cloning technology
Insert Structure linear
Update Date 12-MAR-2015
Organism Homo sapiens (human)
Product G-protein coupled receptor 143 isoform X1
Comment MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NT_167197.2) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On Mar 12, 2015 this sequence version replaced gi:530421153. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Homo sapiens Annotation Release 107 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 6.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
ATGGCCTCCC CGCGCCTAGG GACCTTCTGC TGCCCCACGC GGGACGCAGC CACGCAGCTC 
GTGCTGAGCT TCCAGCCGCG GGCCTTCCAC GCGCTCTGCC TGGGCAGCGG CGGGCTCCGC
TTGGCGCTGG GCCTTCTGCA GCTGCTGCCC GGCCGCCGGC CCGCGGGCCC CGGGTCCCCC
GCGACGTCCC CGCCGGCCTC GGTCCGCATC CTGCGCGCTG CCGCTGCCTG CGACCTTCTC
GGCTGCCTGG GTATGGTGAT CCGGTCCACC GTGTGGTTAG GATTCCCAAA TTTTGTTGAC
AGCGTCTCGG ATATGAACCA CACGGAAATT TGGCCTGCTG CTTTCTGCGT GGGGAGTGCG
ATGTGGATCC AGCTGTTGTA CAGTGCCTGC TTCTGGTGGC TGTTTTGCTA TGCAGTGGAT
GCTTATCTGG TGATCCGGAG ATCGGCAGGA CTGAGCACCA TCCTGCTGTA TCACATCATG
GCGTGGGGCC TGGCCACCCT GCTCTGTGTG GAGGGAGCCG CCATGCTCTA CTACCCTTCC
GTGTCCAGGT GTGAGCGGGG CCTGGACCAC GCCATCCCCC ACTATGTCAC CATGTACCTG
CCCCTGCTGC TGGTTCTCGT GGCGAACCCC ATCCTGTTCC AAAAGACAGT GACTGCAGTG
GCCTCTTTAC TTAAAGGAAG ACAAGGCATT TACACGGAGA ACGAGAGGAG GATGGGAGCC
GTGATCAAGA TCCGATTTTT CAAAATCATG CTGGTTTTAA TTATTTGTTG GTTGTCGAAT
ATCATCAATG AAAGCCTTTT ATTCTATCTT GAGATGCAAA CAGATATCAA TGGAGGTTCT
TTGAAACCTG TCAGAACTGC AGCCAAGACC ACATGGTTTA TTATGGGAAT CCTGAATCCA
GCCCAGGGAT TTCTCTTGTC TTTGGCCTTC TACGGCTGGA CAGGATGCAG CCTGGGTTTT
CAGTCTCCCA GGAAGGAGAT CCAGTGGGAA TCACTGACCA CCTCGGCTGC TGAGGGGGCT
CACCCATCCC CACTGATGCC CCATGAAAAC CCTGCTTCCG GGAAGGTGTC TCAAGTGGGT
GGGCAGACTT CTGACGAAGC CCTGAGCATG CTGTCTGAAG ATGAGATGAA TGCTAGGACT
TTGACCAAAG TTGGTCCATG A

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq XP_005274598.1
CDS38..1198
Misc Feature(1)38..1159(+)
Translation

Target ORF information:

RefSeq Version XM_005274541
Organism Homo sapiens (human)
Definition PREDICTED: Homo sapiens G protein-coupled receptor 143 (GPR143), transcript variant X1, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
XM_005274541

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
ATGGCCTCCC CGCGCCTAGG GACCTTCTGC TGCCCCACGC GGGACGCAGC CACGCAGCTC 
GTGCTGAGCT TCCAGCCGCG GGCCTTCCAC GCGCTCTGCC TGGGCAGCGG CGGGCTCCGC
TTGGCGCTGG GCCTTCTGCA GCTGCTGCCC GGCCGCCGGC CCGCGGGCCC CGGGTCCCCC
GCGACGTCCC CGCCGGCCTC GGTCCGCATC CTGCGCGCTG CCGCTGCCTG CGACCTTCTC
GGCTGCCTGG GTATGGTGAT CCGGTCCACC GTGTGGTTAG GATTCCCAAA TTTTGTTGAC
AGCGTCTCGG ATATGAACCA CACGGAAATT TGGCCTGCTG CTTTCTGCGT GGGGAGTGCG
ATGTGGATCC AGCTGTTGTA CAGTGCCTGC TTCTGGTGGC TGTTTTGCTA TGCAGTGGAT
GCTTATCTGG TGATCCGGAG ATCGGCAGGA CTGAGCACCA TCCTGCTGTA TCACATCATG
GCGTGGGGCC TGGCCACCCT GCTCTGTGTG GAGGGAGCCG CCATGCTCTA CTACCCTTCC
GTGTCCAGGT GTGAGCGGGG CCTGGACCAC GCCATCCCCC ACTATGTCAC CATGTACCTG
CCCCTGCTGC TGGTTCTCGT GGCGAACCCC ATCCTGTTCC AAAAGACAGT GACTGCAGTG
GCCTCTTTAC TTAAAGGAAG ACAAGGCATT TACACGGAGA ACGAGAGGAG GATGGGAGCC
GTGATCAAGA TCCGATTTTT CAAAATCATG CTGGTTTTAA TTATTTGTTG GTTGTCGAAT
ATCATCAATG AAAGCCTTTT ATTCTATCTT GAGATGCAAA CAGATATCAA TGGAGGTTCT
TTGAAACCTG TCAGAACTGC AGCCAAGACC ACATGGTTTA TTATGGGAAT CCTGAATCCA
GCCCAGGGAT TTCTCTTGTC TTTGGCCTTC TACGGCTGGA CAGGATGCAG CCTGGGTTTT
CAGTCTCCCA GGAAGGAGAT CCAGTGGGAA TCACTGACCA CCTCGGCTGC TGAGGGGGCT
CACCCATCCC CACTGATGCC CCATGAAAAC CCTGCTTCCG GGAAGGTGTC TCAAGTGGGT
GGGCAGACTT CTGACGAAGC CCTGAGCATG CTGTCTGAAG ATGAGATGAA TGCTAGGACT
TTGACCAAAG TTGGTCCATG A

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OHu18715
Clone ID Related Accession (Same CDS sequence) NM_000273
Accession Version NM_000273.2 Documents for ORF clone product in dufault vector
Sequence Information ORF Nucleotide Sequence (Length: 1215bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ® Seamless cloning technology
Insert Structure linear
Update Date 15-MAR-2015
Organism Homo sapiens (human)
Product G-protein coupled receptor 143
Comment REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from BC068977.1, Z48804.1 and BU188283.1. This sequence is a reference standard in the RefSeqGene project. On Dec 4, 2009 this sequence version replaced gi:4557806. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##RefSeq-Attributes-START## CDS uses downstream in-frame AUG :: community standard (PMID:11793467) ##RefSeq-Attributes-END## ##Evidence-Data-START## Transcript exon combination :: BC068977.1, Z48804.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2142853 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
ATGGCCTCCC CGCGCCTAGG GACCTTCTGC TGCCCCACGC GGGACGCAGC CACGCAGCTC 
GTGCTGAGCT TCCAGCCGCG GGCCTTCCAC GCGCTCTGCC TGGGCAGCGG CGGGCTCCGC
TTGGCGCTGG GCCTTCTGCA GCTGCTGCCC GGCCGCCGGC CCGCGGGCCC CGGGTCCCCC
GCGACGTCCC CGCCGGCCTC GGTCCGCATC CTGCGCGCTG CCGCTGCCTG CGACCTTCTC
GGCTGCCTGG GTATGGTGAT CCGGTCCACC GTGTGGTTAG GATTCCCAAA TTTTGTTGAC
AGCGTCTCGG ATATGAACCA CACGGAAATT TGGCCTGCTG CTTTCTGCGT GGGGAGTGCG
ATGTGGATCC AGCTGTTGTA CAGTGCCTGC TTCTGGTGGC TGTTTTGCTA TGCAGTGGAT
GCTTATCTGG TGATCCGGAG ATCGGCAGGA CTGAGCACCA TCCTGCTGTA TCACATCATG
GCGTGGGGCC TGGCCACCCT GCTCTGTGTG GAGGGAGCCG CCATGCTCTA CTACCCTTCC
GTGTCCAGGT GTGAGCGGGG CCTGGACCAC GCCATCCCCC ACTATGTCAC CATGTACCTG
CCCCTGCTGC TGGTTCTCGT GGCGAACCCC ATCCTGTTCC AAAAGACAGT GACTGCAGTG
GCCTCTTTAC TTAAAGGAAG ACAAGGCATT TACACGGAGA ACGAGAGGAG GATGGGAGCC
GTGATCAAGA TCCGATTTTT CAAAATCATG CTGGTTTTAA TTATTTGTTG GTTGTCGAAT
ATCATCAATG AAAGCCTTTT ATTCTATCTT GAGATGCAAA CAGATATCAA TGGAGGTTCT
TTGAAACCTG TCAGAACTGC AGCCAAGACC ACATGGTTTA TTATGGGAAT CCTGAATCCA
GCCCAGGGAT TTCTCTTGTC TTTGGCCTTC TACGGCTGGA CAGGATGCAG CCTGGGTTTT
CAGTCTCCCA GGAAGGAGAT CCAGTGGGAA TCACTGACCA CCTCGGCTGC TGAGGGGGCT
CACCCATCCC CACTGATGCC CCATGAAAAC CCTGCTTCCG GGAAGGTGTC TCAAGTGGGT
GGGCAGACTT CTGACGAAGC CCTGAGCATG CTGTCTGAAG GTTCTGATGC CAGCACAATT
GAAATTCACA CTGCAAGTGA ATCCTGCAAC AAAAATGAGG GTGACCCTGC TCTCCCAACC
CATGGAGACC TATGA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq NP_000264.2
CDS149..1363
Misc Feature(1)62..64(+)
Misc Feature(2)149..1360(+)
Misc Feature(3)233..295(+)
Misc Feature(4)383..445(+)
Misc Feature(5)521..583(+)
Misc Feature(6)596..658(+)
Misc Feature(7)722..784(+)
Misc Feature(8)809..862(+)
Misc Feature(9)812..841(+)
Misc Feature(10)893..955(+)
Misc Feature(11)1025..1087(+)
Misc Feature(12)1133..1138(+)
Exon (1)1..398
Gene:GPR143
Gene Synonym:
Exon (2)399..508
Gene:GPR143
Gene Synonym:
Exon (3)509..603
Gene:GPR143
Gene Synonym:
Exon (4)604..696
Gene:GPR143
Gene Synonym:
Exon (5)697..806
Gene:GPR143
Gene Synonym:
Exon (6)807..915
Gene:GPR143
Gene Synonym:
Exon (7)916..1033
Gene:GPR143
Gene Synonym:
Exon (8)1034..1268
Gene:GPR143
Gene Synonym:
Exon (9)1269..1696
Gene:GPR143
Gene Synonym:
Translation

Target ORF information:

RefSeq Version NM_000273
Organism Homo sapiens (human)
Definition Homo sapiens G protein-coupled receptor 143 (GPR143), mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
NM_000273

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
ATGGCCTCCC CGCGCCTAGG GACCTTCTGC TGCCCCACGC GGGACGCAGC CACGCAGCTC 
GTGCTGAGCT TCCAGCCGCG GGCCTTCCAC GCGCTCTGCC TGGGCAGCGG CGGGCTCCGC
TTGGCGCTGG GCCTTCTGCA GCTGCTGCCC GGCCGCCGGC CCGCGGGCCC CGGGTCCCCC
GCGACGTCCC CGCCGGCCTC GGTCCGCATC CTGCGCGCTG CCGCTGCCTG CGACCTTCTC
GGCTGCCTGG GTATGGTGAT CCGGTCCACC GTGTGGTTAG GATTCCCAAA TTTTGTTGAC
AGCGTCTCGG ATATGAACCA CACGGAAATT TGGCCTGCTG CTTTCTGCGT GGGGAGTGCG
ATGTGGATCC AGCTGTTGTA CAGTGCCTGC TTCTGGTGGC TGTTTTGCTA TGCAGTGGAT
GCTTATCTGG TGATCCGGAG ATCGGCAGGA CTGAGCACCA TCCTGCTGTA TCACATCATG
GCGTGGGGCC TGGCCACCCT GCTCTGTGTG GAGGGAGCCG CCATGCTCTA CTACCCTTCC
GTGTCCAGGT GTGAGCGGGG CCTGGACCAC GCCATCCCCC ACTATGTCAC CATGTACCTG
CCCCTGCTGC TGGTTCTCGT GGCGAACCCC ATCCTGTTCC AAAAGACAGT GACTGCAGTG
GCCTCTTTAC TTAAAGGAAG ACAAGGCATT TACACGGAGA ACGAGAGGAG GATGGGAGCC
GTGATCAAGA TCCGATTTTT CAAAATCATG CTGGTTTTAA TTATTTGTTG GTTGTCGAAT
ATCATCAATG AAAGCCTTTT ATTCTATCTT GAGATGCAAA CAGATATCAA TGGAGGTTCT
TTGAAACCTG TCAGAACTGC AGCCAAGACC ACATGGTTTA TTATGGGAAT CCTGAATCCA
GCCCAGGGAT TTCTCTTGTC TTTGGCCTTC TACGGCTGGA CAGGATGCAG CCTGGGTTTT
CAGTCTCCCA GGAAGGAGAT CCAGTGGGAA TCACTGACCA CCTCGGCTGC TGAGGGGGCT
CACCCATCCC CACTGATGCC CCATGAAAAC CCTGCTTCCG GGAAGGTGTC TCAAGTGGGT
GGGCAGACTT CTGACGAAGC CCTGAGCATG CTGTCTGAAG GTTCTGATGC CAGCACAATT
GAAATTCACA CTGCAAGTGA ATCCTGCAAC AAAAATGAGG GTGACCCTGC TCTCCCAACC
CATGGAGACC TATGA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

 
*
*
*
*