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PITX2 cDNA ORF clone, Homo sapiens (human)

Gene Symbol PITX2
Entrez Gene ID 5308
Full Name paired-like homeodomain 2
Synonyms ARP1, Brx1, IDG2, IGDS, IGDS2, IHG2, IRID2, Otlx2, PTX2, RGS, RIEG, RIEG1, RS
Gene Type protein-coding
Organism Homo sapiens (human)
Genome

4

4q25

Summary This gene encodes a member of the RIEG/PITX homeobox family, which is in the bicoid class of homeodomain proteins. The encoded protein acts as a transcription factor and regulates procollagen lysyl hydroxylase gene expression. This protein plays a role in the terminal differentiation of somatotroph and lactotroph cell phenotypes, is involved in the development of the eye, tooth and abdominal organs, and acts as a transcriptional regulator involved in basal and hormone-regulated activity of prolactin. Mutations in this gene are associated with Axenfeld-Rieger syndrome, iridogoniodysgenesis syndrome, and sporadic cases of Peters anomaly. A similar protein in other vertebrates is involved in the determination of left-right asymmetry during development. Alternatively spliced transcript variants encoding distinct isoforms have been described. [provided by RefSeq, Jul 2008]. lac of sum
Disorder MIM:

601542

Disorder Html: Axenfeld-Rieger syndrome, type 1, 180500 (3); Iridogoniodysgenesis,

mRNA and Protein(s)

mRNA Protein Name
XM_006714235 XP_006714298 pituitary homeobox 2 isoform X1
XM_011532027 XP_011530329 pituitary homeobox 2 isoform X2
NM_001204397 NP_001191326 pituitary homeobox 2 isoform b
NM_001204398 NP_001191327 pituitary homeobox 2 isoform b
NM_001204399 NP_001191328 pituitary homeobox 2 isoform a
NM_153426 NP_700475 pituitary homeobox 2 isoform b
NM_153427 NP_700476 pituitary homeobox 2 isoform a
NM_000325 NP_000316 pituitary homeobox 2 isoform c



Homo sapiens (human) PITX2 NP_000316.2
Pan troglodytes (chimpanzee) PITX2 XP_001141234.1
Macaca mulatta (Rhesus monkey) PITX2 XP_001091288.1
Canis lupus familiaris (dog) PITX2 XP_851370.1
Bos taurus (cattle) PITX2 NP_001091460.1
Mus musculus (house mouse) Pitx2 NP_001035967.1
Rattus norvegicus (Norway rat) Pitx2 NP_001035970.1
Gallus gallus (chicken) PITX2 NP_990341.1
Danio rerio (zebrafish) pitx2 NP_571050.1
Drosophila melanogaster (fruit fly) Ptx1 NP_733410.2
Xenopus (Silurana) tropicalis (western clawed frog) pitx2 NP_001017227.1


GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following PITX2 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the PITX2 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

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***CloneID RefSeq Accession Definition **Vector *Turnaround time Price (USD) Select
OHu17508 XM_006714235 PREDICTED: Homo sapiens paired-like homeodomain 2 (PITX2), transcript variant X1, mRNA. pcDNA3.1+/C-(K)DYK or customized vector 7-9 $139.30
$199.00
OHu17480
XM_011532027 PREDICTED: Homo sapiens paired-like homeodomain 2 (PITX2), transcript variant X2, mRNA. pcDNA3.1+/C-(K)DYK or customized vector
in pcDNA3.1+/C-(K)DYK
$99.50-$139.30
$199.00
OHu17508 NM_001204397 Homo sapiens paired-like homeodomain 2 (PITX2), transcript variant 4, mRNA. pcDNA3.1+/C-(K)DYK or customized vector 7-9 $139.30
$199.00
OHu17508 NM_001204398 Homo sapiens paired-like homeodomain 2 (PITX2), transcript variant 5, mRNA. pcDNA3.1+/C-(K)DYK or customized vector 7-9 $139.30
$199.00
OHu17480
NM_001204399 Homo sapiens paired-like homeodomain 2 (PITX2), transcript variant 6, mRNA. pcDNA3.1+/C-(K)DYK or customized vector
in pcDNA3.1+/C-(K)DYK
$99.50-$139.30
$199.00
OHu17508 NM_153426 Homo sapiens paired-like homeodomain 2 (PITX2), transcript variant 2, mRNA. pcDNA3.1+/C-(K)DYK or customized vector 7-9 $139.30
$199.00
OHu17480
NM_153427 Homo sapiens paired-like homeodomain 2 (PITX2), transcript variant 1, mRNA. pcDNA3.1+/C-(K)DYK or customized vector
in pcDNA3.1+/C-(K)DYK
$99.50-$139.30
$199.00
OHu17360
NM_000325 Homo sapiens paired-like homeodomain 2 (PITX2), transcript variant 3, mRNA. pcDNA3.1+/C-(K)DYK or customized vector
in pcDNA3.1+/C-(K)DYK
$99.50-$139.30
$199.00
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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.


CloneID OHu17508
Clone ID Related Accession (Same CDS sequence) NM_001204397 , NM_001204398 , NM_153426 , XM_006714235
Accession Version XM_006714235.2 Documents for ORF clone product in dufault vector
Sequence Information ORF Nucleotide Sequence (Length: 954bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ® Seamless cloning technology
Structure linear
Update Date 12-MAR-2015
Organism Homo sapiens (human)
Product pituitary homeobox 2 isoform X1
Comment MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NT_016354.20) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Mar 12, 2015 this sequence version replaced gi:578809166. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Homo sapiens Annotation Release 107 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 6.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
ATGGAGACCA ACTGCCGCAA ACTGGTGTCG GCGTGTGTGC AATTAGGCGT GCAGCCGGCG 
GCCGTTGAAT GTCTCTTCTC CAAAGACTCC GAAATCAAAA AGGTCGAGTT CACGGACTCT
CCTGAGAGCC GAAAAGAGGC AGCCAGCAGC AAGTTCTTCC CGCGGCAGCA TCCTGGCGCC
AATGAGAAAG ATAAAAGCCA GCAGGGGAAG AATGAGGACG TGGGCGCCGA GGACCCGTCT
AAGAAGAAGC GGCAAAGGCG GCAGCGGACT CACTTTACCA GCCAGCAGCT CCAGGAGCTG
GAGGCCACTT TCCAGAGGAA CCGCTACCCG GACATGTCCA CACGCGAAGA AATCGCTGTG
TGGACCAACC TTACGGAAGC CCGAGTCCGG GTTTGGTTCA AGAATCGTCG GGCCAAATGG
AGAAAGAGGG AGCGCAACCA GCAGGCCGAG CTATGCAAGA ATGGCTTCGG GCCGCAGTTC
AATGGGCTCA TGCAGCCCTA CGACGACATG TACCCAGGCT ATTCCTACAA CAACTGGGCC
GCCAAGGGCC TTACATCCGC CTCCCTATCC ACCAAGAGCT TCCCCTTCTT CAACTCTATG
AACGTCAACC CCCTGTCATC ACAGAGCATG TTTTCCCCAC CCAACTCTAT CTCGTCCATG
AGCATGTCGT CCAGCATGGT GCCCTCAGCA GTGACAGGCG TCCCGGGCTC CAGTCTCAAC
AGCCTGAATA ACTTGAACAA CCTGAGTAGC CCGTCGCTGA ATTCCGCGGT GCCGACGCCT
GCCTGTCCTT ACGCGCCGCC GACTCCTCCG TATGTTTATA GGGACACGTG TAACTCGAGC
CTGGCCAGCC TGAGACTGAA AGCAAAGCAG CACTCCAGCT TCGGCTACGC CAGCGTGCAG
AACCCGGCCT CCAACCTGAG TGCTTGCCAG TATGCAGTGG ACCGGCCCGT GTGA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq XP_006714298.1
CDS30..983
Misc Feature(1)285..461(+)
Misc Feature(2)285..455(+)
Misc Feature(3)291..443(+)
Misc Feature(4)849..905(+)
Translation

Target ORF information:

RefSeq Version XM_006714235
Organism Homo sapiens (human)
Definition PREDICTED: Homo sapiens paired-like homeodomain 2 (PITX2), transcript variant X1, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
XM_006714235

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
ATGGAGACCA ACTGCCGCAA ACTGGTGTCG GCGTGTGTGC AATTAGGCGT GCAGCCGGCG 
GCCGTTGAAT GTCTCTTCTC CAAAGACTCC GAAATCAAAA AGGTCGAGTT CACGGACTCT
CCTGAGAGCC GAAAAGAGGC AGCCAGCAGC AAGTTCTTCC CGCGGCAGCA TCCTGGCGCC
AATGAGAAAG ATAAAAGCCA GCAGGGGAAG AATGAGGACG TGGGCGCCGA GGACCCGTCT
AAGAAGAAGC GGCAAAGGCG GCAGCGGACT CACTTTACCA GCCAGCAGCT CCAGGAGCTG
GAGGCCACTT TCCAGAGGAA CCGCTACCCG GACATGTCCA CACGCGAAGA AATCGCTGTG
TGGACCAACC TTACGGAAGC CCGAGTCCGG GTTTGGTTCA AGAATCGTCG GGCCAAATGG
AGAAAGAGGG AGCGCAACCA GCAGGCCGAG CTATGCAAGA ATGGCTTCGG GCCGCAGTTC
AATGGGCTCA TGCAGCCCTA CGACGACATG TACCCAGGCT ATTCCTACAA CAACTGGGCC
GCCAAGGGCC TTACATCCGC CTCCCTATCC ACCAAGAGCT TCCCCTTCTT CAACTCTATG
AACGTCAACC CCCTGTCATC ACAGAGCATG TTTTCCCCAC CCAACTCTAT CTCGTCCATG
AGCATGTCGT CCAGCATGGT GCCCTCAGCA GTGACAGGCG TCCCGGGCTC CAGTCTCAAC
AGCCTGAATA ACTTGAACAA CCTGAGTAGC CCGTCGCTGA ATTCCGCGGT GCCGACGCCT
GCCTGTCCTT ACGCGCCGCC GACTCCTCCG TATGTTTATA GGGACACGTG TAACTCGAGC
CTGGCCAGCC TGAGACTGAA AGCAAAGCAG CACTCCAGCT TCGGCTACGC CAGCGTGCAG
AACCCGGCCT CCAACCTGAG TGCTTGCCAG TATGCAGTGG ACCGGCCCGT GTGA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OHu17480
Clone ID Related Accession (Same CDS sequence) NM_001204399 , NM_153427 , XM_011532027
Accession Version XM_011532027.1 Documents for ORF clone product in dufault vector
Sequence Information ORF Nucleotide Sequence (Length: 816bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags COA
ORF Insert Method CloneEZ® Seamless cloning technology
Structure linear
Update Date 12-MAR-2015
Organism Homo sapiens (human)
Product pituitary homeobox 2 isoform X2
Comment MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NT_016354.20) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Homo sapiens Annotation Release 107 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 6.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

1
61
121
181
241
301
361
421
481
541
601
661
721
781
ATGGAGACCA ACTGCCGCAA ACTGGTGTCG GCGTGTGTGC AATTAGAGAA AGATAAAAGC 
CAGCAGGGGA AGAATGAGGA CGTGGGCGCC GAGGACCCGT CTAAGAAGAA GCGGCAAAGG
CGGCAGCGGA CTCACTTTAC CAGCCAGCAG CTCCAGGAGC TGGAGGCCAC TTTCCAGAGG
AACCGCTACC CGGACATGTC CACACGCGAA GAAATCGCTG TGTGGACCAA CCTTACGGAA
GCCCGAGTCC GGGTTTGGTT CAAGAATCGT CGGGCCAAAT GGAGAAAGAG GGAGCGCAAC
CAGCAGGCCG AGCTATGCAA GAATGGCTTC GGGCCGCAGT TCAATGGGCT CATGCAGCCC
TACGACGACA TGTACCCAGG CTATTCCTAC AACAACTGGG CCGCCAAGGG CCTTACATCC
GCCTCCCTAT CCACCAAGAG CTTCCCCTTC TTCAACTCTA TGAACGTCAA CCCCCTGTCA
TCACAGAGCA TGTTTTCCCC ACCCAACTCT ATCTCGTCCA TGAGCATGTC GTCCAGCATG
GTGCCCTCAG CAGTGACAGG CGTCCCGGGC TCCAGTCTCA ACAGCCTGAA TAACTTGAAC
AACCTGAGTA GCCCGTCGCT GAATTCCGCG GTGCCGACGC CTGCCTGTCC TTACGCGCCG
CCGACTCCTC CGTATGTTTA TAGGGACACG TGTAACTCGA GCCTGGCCAG CCTGAGACTG
AAAGCAAAGC AGCACTCCAG CTTCGGCTAC GCCAGCGTGC AGAACCCGGC CTCCAACCTG
AGTGCTTGCC AGTATGCAGT GGACCGGCCC GTGTGA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq XP_011530329.1
CDS1442..2257
Misc Feature(1)1559..1735(+)
Misc Feature(2)1559..1729(+)
Misc Feature(3)1565..1717(+)
Misc Feature(4)2123..2179(+)
Translation

Target ORF information:

RefSeq Version XM_011532027
Organism Homo sapiens (human)
Definition PREDICTED: Homo sapiens paired-like homeodomain 2 (PITX2), transcript variant X2, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
XM_011532027

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
ATGGAGACCA ACTGCCGCAA ACTGGTGTCG GCGTGTGTGC AATTAGAGAA AGATAAAAGC 
CAGCAGGGGA AGAATGAGGA CGTGGGCGCC GAGGACCCGT CTAAGAAGAA GCGGCAAAGG
CGGCAGCGGA CTCACTTTAC CAGCCAGCAG CTCCAGGAGC TGGAGGCCAC TTTCCAGAGG
AACCGCTACC CGGACATGTC CACACGCGAA GAAATCGCTG TGTGGACCAA CCTTACGGAA
GCCCGAGTCC GGGTTTGGTT CAAGAATCGT CGGGCCAAAT GGAGAAAGAG GGAGCGCAAC
CAGCAGGCCG AGCTATGCAA GAATGGCTTC GGGCCGCAGT TCAATGGGCT CATGCAGCCC
TACGACGACA TGTACCCAGG CTATTCCTAC AACAACTGGG CCGCCAAGGG CCTTACATCC
GCCTCCCTAT CCACCAAGAG CTTCCCCTTC TTCAACTCTA TGAACGTCAA CCCCCTGTCA
TCACAGAGCA TGTTTTCCCC ACCCAACTCT ATCTCGTCCA TGAGCATGTC GTCCAGCATG
GTGCCCTCAG CAGTGACAGG CGTCCCGGGC TCCAGTCTCA ACAGCCTGAA TAACTTGAAC
AACCTGAGTA GCCCGTCGCT GAATTCCGCG GTGCCGACGC CTGCCTGTCC TTACGCGCCG
CCGACTCCTC CGTATGTTTA TAGGGACACG TGTAACTCGA GCCTGGCCAG CCTGAGACTG
AAAGCAAAGC AGCACTCCAG CTTCGGCTAC GCCAGCGTGC AGAACCCGGC CTCCAACCTG
AGTGCTTGCC AGTATGCAGT GGACCGGCCC GTGTGA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OHu17508
Clone ID Related Accession (Same CDS sequence) NM_001204397 , NM_001204398 , NM_153426 , XM_006714235
Accession Version NM_001204397.1 Documents for ORF clone product in dufault vector
Sequence Information ORF Nucleotide Sequence (Length: 954bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ® Seamless cloning technology
Structure linear
Update Date 15-MAR-2015
Organism Homo sapiens (human)
Product pituitary homeobox 2 isoform b
Comment REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from BP372081.1, AK127829.1, BX380370.2, U69961.1 and BC106010.1. Transcript Variant: This variant (4) has an additional exon in the 5' UTR, as compared to variant 2. Variants 2, 4 and 5 encode the same isoform b. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AK127829.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA2153307 [ECO:0000350] ##Evidence-Data-END##

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
ATGGAGACCA ACTGCCGCAA ACTGGTGTCG GCGTGTGTGC AATTAGGCGT GCAGCCGGCG 
GCCGTTGAAT GTCTCTTCTC CAAAGACTCC GAAATCAAAA AGGTCGAGTT CACGGACTCT
CCTGAGAGCC GAAAAGAGGC AGCCAGCAGC AAGTTCTTCC CGCGGCAGCA TCCTGGCGCC
AATGAGAAAG ATAAAAGCCA GCAGGGGAAG AATGAGGACG TGGGCGCCGA GGACCCGTCT
AAGAAGAAGC GGCAAAGGCG GCAGCGGACT CACTTTACCA GCCAGCAGCT CCAGGAGCTG
GAGGCCACTT TCCAGAGGAA CCGCTACCCG GACATGTCCA CACGCGAAGA AATCGCTGTG
TGGACCAACC TTACGGAAGC CCGAGTCCGG GTTTGGTTCA AGAATCGTCG GGCCAAATGG
AGAAAGAGGG AGCGCAACCA GCAGGCCGAG CTATGCAAGA ATGGCTTCGG GCCGCAGTTC
AATGGGCTCA TGCAGCCCTA CGACGACATG TACCCAGGCT ATTCCTACAA CAACTGGGCC
GCCAAGGGCC TTACATCCGC CTCCCTATCC ACCAAGAGCT TCCCCTTCTT CAACTCTATG
AACGTCAACC CCCTGTCATC ACAGAGCATG TTTTCCCCAC CCAACTCTAT CTCGTCCATG
AGCATGTCGT CCAGCATGGT GCCCTCAGCA GTGACAGGCG TCCCGGGCTC CAGTCTCAAC
AGCCTGAATA ACTTGAACAA CCTGAGTAGC CCGTCGCTGA ATTCCGCGGT GCCGACGCCT
GCCTGTCCTT ACGCGCCGCC GACTCCTCCG TATGTTTATA GGGACACGTG TAACTCGAGC
CTGGCCAGCC TGAGACTGAA AGCAAAGCAG CACTCCAGCT TCGGCTACGC CAGCGTGCAG
AACCCGGCCT CCAACCTGAG TGCTTGCCAG TATGCAGTGG ACCGGCCCGT GTGA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq NP_001191326.1
CDS1824..2777
Misc Feature(1)1815..1817(+)
Misc Feature(2)2079..2255(+)
Misc Feature(3)2079..2249(+)
Misc Feature(4)2085..2237(+)
Misc Feature(5)2643..2699(+)
Misc Feature(6)2658..2699(+)
Misc Feature(7)2676..2690(+)
Exon (1)1..205
Gene:PITX2
Gene Synonym:
Exon (2)206..1579
Gene:PITX2
Gene Synonym:
Exon (3)1580..1813
Gene:PITX2
Gene Synonym:
Exon (4)1814..1869
Gene:PITX2
Gene Synonym:
Exon (5)1870..2007
Gene:PITX2
Gene Synonym:
Exon (6)2008..2213
Gene:PITX2
Gene Synonym:
Exon (7)2214..3479
Gene:PITX2
Gene Synonym:
Translation

Target ORF information:

RefSeq Version NM_001204397
Organism Homo sapiens (human)
Definition Homo sapiens paired-like homeodomain 2 (PITX2), transcript variant 4, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
NM_001204397

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
ATGGAGACCA ACTGCCGCAA ACTGGTGTCG GCGTGTGTGC AATTAGGCGT GCAGCCGGCG 
GCCGTTGAAT GTCTCTTCTC CAAAGACTCC GAAATCAAAA AGGTCGAGTT CACGGACTCT
CCTGAGAGCC GAAAAGAGGC AGCCAGCAGC AAGTTCTTCC CGCGGCAGCA TCCTGGCGCC
AATGAGAAAG ATAAAAGCCA GCAGGGGAAG AATGAGGACG TGGGCGCCGA GGACCCGTCT
AAGAAGAAGC GGCAAAGGCG GCAGCGGACT CACTTTACCA GCCAGCAGCT CCAGGAGCTG
GAGGCCACTT TCCAGAGGAA CCGCTACCCG GACATGTCCA CACGCGAAGA AATCGCTGTG
TGGACCAACC TTACGGAAGC CCGAGTCCGG GTTTGGTTCA AGAATCGTCG GGCCAAATGG
AGAAAGAGGG AGCGCAACCA GCAGGCCGAG CTATGCAAGA ATGGCTTCGG GCCGCAGTTC
AATGGGCTCA TGCAGCCCTA CGACGACATG TACCCAGGCT ATTCCTACAA CAACTGGGCC
GCCAAGGGCC TTACATCCGC CTCCCTATCC ACCAAGAGCT TCCCCTTCTT CAACTCTATG
AACGTCAACC CCCTGTCATC ACAGAGCATG TTTTCCCCAC CCAACTCTAT CTCGTCCATG
AGCATGTCGT CCAGCATGGT GCCCTCAGCA GTGACAGGCG TCCCGGGCTC CAGTCTCAAC
AGCCTGAATA ACTTGAACAA CCTGAGTAGC CCGTCGCTGA ATTCCGCGGT GCCGACGCCT
GCCTGTCCTT ACGCGCCGCC GACTCCTCCG TATGTTTATA GGGACACGTG TAACTCGAGC
CTGGCCAGCC TGAGACTGAA AGCAAAGCAG CACTCCAGCT TCGGCTACGC CAGCGTGCAG
AACCCGGCCT CCAACCTGAG TGCTTGCCAG TATGCAGTGG ACCGGCCCGT GTGA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OHu17508
Clone ID Related Accession (Same CDS sequence) NM_001204397 , NM_001204398 , NM_153426 , XM_006714235
Accession Version NM_001204398.1 Documents for ORF clone product in dufault vector
Sequence Information ORF Nucleotide Sequence (Length: 954bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ® Seamless cloning technology
Structure linear
Update Date 15-MAR-2015
Organism Homo sapiens (human)
Product pituitary homeobox 2 isoform b
Comment REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from BP372081.1 and BC106010.1. Transcript Variant: This variant (5) lacks an exon in the 5' UTR, as compared to variant 2. Variants 2, 4 and 5 encode the same isoform b. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BX403546.2 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2153307 [ECO:0000348] ##Evidence-Data-END##

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
ATGGAGACCA ACTGCCGCAA ACTGGTGTCG GCGTGTGTGC AATTAGGCGT GCAGCCGGCG 
GCCGTTGAAT GTCTCTTCTC CAAAGACTCC GAAATCAAAA AGGTCGAGTT CACGGACTCT
CCTGAGAGCC GAAAAGAGGC AGCCAGCAGC AAGTTCTTCC CGCGGCAGCA TCCTGGCGCC
AATGAGAAAG ATAAAAGCCA GCAGGGGAAG AATGAGGACG TGGGCGCCGA GGACCCGTCT
AAGAAGAAGC GGCAAAGGCG GCAGCGGACT CACTTTACCA GCCAGCAGCT CCAGGAGCTG
GAGGCCACTT TCCAGAGGAA CCGCTACCCG GACATGTCCA CACGCGAAGA AATCGCTGTG
TGGACCAACC TTACGGAAGC CCGAGTCCGG GTTTGGTTCA AGAATCGTCG GGCCAAATGG
AGAAAGAGGG AGCGCAACCA GCAGGCCGAG CTATGCAAGA ATGGCTTCGG GCCGCAGTTC
AATGGGCTCA TGCAGCCCTA CGACGACATG TACCCAGGCT ATTCCTACAA CAACTGGGCC
GCCAAGGGCC TTACATCCGC CTCCCTATCC ACCAAGAGCT TCCCCTTCTT CAACTCTATG
AACGTCAACC CCCTGTCATC ACAGAGCATG TTTTCCCCAC CCAACTCTAT CTCGTCCATG
AGCATGTCGT CCAGCATGGT GCCCTCAGCA GTGACAGGCG TCCCGGGCTC CAGTCTCAAC
AGCCTGAATA ACTTGAACAA CCTGAGTAGC CCGTCGCTGA ATTCCGCGGT GCCGACGCCT
GCCTGTCCTT ACGCGCCGCC GACTCCTCCG TATGTTTATA GGGACACGTG TAACTCGAGC
CTGGCCAGCC TGAGACTGAA AGCAAAGCAG CACTCCAGCT TCGGCTACGC CAGCGTGCAG
AACCCGGCCT CCAACCTGAG TGCTTGCCAG TATGCAGTGG ACCGGCCCGT GTGA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq NP_001191327.1
CDS216..1169
Misc Feature(1)207..209(+)
Misc Feature(2)471..647(+)
Misc Feature(3)471..641(+)
Misc Feature(4)477..629(+)
Misc Feature(5)1035..1091(+)
Misc Feature(6)1050..1091(+)
Misc Feature(7)1068..1082(+)
Exon (1)1..205
Gene:PITX2
Gene Synonym:
Exon (2)206..261
Gene:PITX2
Gene Synonym:
Exon (3)262..399
Gene:PITX2
Gene Synonym:
Exon (4)400..605
Gene:PITX2
Gene Synonym:
Exon (5)606..1871
Gene:PITX2
Gene Synonym:
Translation

Target ORF information:

RefSeq Version NM_001204398
Organism Homo sapiens (human)
Definition Homo sapiens paired-like homeodomain 2 (PITX2), transcript variant 5, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
NM_001204398

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
ATGGAGACCA ACTGCCGCAA ACTGGTGTCG GCGTGTGTGC AATTAGGCGT GCAGCCGGCG 
GCCGTTGAAT GTCTCTTCTC CAAAGACTCC GAAATCAAAA AGGTCGAGTT CACGGACTCT
CCTGAGAGCC GAAAAGAGGC AGCCAGCAGC AAGTTCTTCC CGCGGCAGCA TCCTGGCGCC
AATGAGAAAG ATAAAAGCCA GCAGGGGAAG AATGAGGACG TGGGCGCCGA GGACCCGTCT
AAGAAGAAGC GGCAAAGGCG GCAGCGGACT CACTTTACCA GCCAGCAGCT CCAGGAGCTG
GAGGCCACTT TCCAGAGGAA CCGCTACCCG GACATGTCCA CACGCGAAGA AATCGCTGTG
TGGACCAACC TTACGGAAGC CCGAGTCCGG GTTTGGTTCA AGAATCGTCG GGCCAAATGG
AGAAAGAGGG AGCGCAACCA GCAGGCCGAG CTATGCAAGA ATGGCTTCGG GCCGCAGTTC
AATGGGCTCA TGCAGCCCTA CGACGACATG TACCCAGGCT ATTCCTACAA CAACTGGGCC
GCCAAGGGCC TTACATCCGC CTCCCTATCC ACCAAGAGCT TCCCCTTCTT CAACTCTATG
AACGTCAACC CCCTGTCATC ACAGAGCATG TTTTCCCCAC CCAACTCTAT CTCGTCCATG
AGCATGTCGT CCAGCATGGT GCCCTCAGCA GTGACAGGCG TCCCGGGCTC CAGTCTCAAC
AGCCTGAATA ACTTGAACAA CCTGAGTAGC CCGTCGCTGA ATTCCGCGGT GCCGACGCCT
GCCTGTCCTT ACGCGCCGCC GACTCCTCCG TATGTTTATA GGGACACGTG TAACTCGAGC
CTGGCCAGCC TGAGACTGAA AGCAAAGCAG CACTCCAGCT TCGGCTACGC CAGCGTGCAG
AACCCGGCCT CCAACCTGAG TGCTTGCCAG TATGCAGTGG ACCGGCCCGT GTGA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OHu17480
Clone ID Related Accession (Same CDS sequence) NM_001204399 , NM_153427 , XM_011532027
Accession Version NM_001204399.1 Documents for ORF clone product in dufault vector
Sequence Information ORF Nucleotide Sequence (Length: 816bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags COA
ORF Insert Method CloneEZ® Seamless cloning technology
Structure linear
Update Date 15-MAR-2015
Organism Homo sapiens (human)
Product pituitary homeobox 2 isoform a
Comment REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from BP372081.1 and BC106010.1. Transcript Variant: This variant (6) lacks an exon in the 5' UTR and an in-frame exon in the 5' CDS, as compared to variant 2. The resulting isoform (a) lacks an internal segment, as compared to isoform b. Variants 1 and 6 encode the same isoform a. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BM706464.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2142853, SAMEA2149398 [ECO:0000348] ##Evidence-Data-END##

1
61
121
181
241
301
361
421
481
541
601
661
721
781
ATGGAGACCA ACTGCCGCAA ACTGGTGTCG GCGTGTGTGC AATTAGAGAA AGATAAAAGC 
CAGCAGGGGA AGAATGAGGA CGTGGGCGCC GAGGACCCGT CTAAGAAGAA GCGGCAAAGG
CGGCAGCGGA CTCACTTTAC CAGCCAGCAG CTCCAGGAGC TGGAGGCCAC TTTCCAGAGG
AACCGCTACC CGGACATGTC CACACGCGAA GAAATCGCTG TGTGGACCAA CCTTACGGAA
GCCCGAGTCC GGGTTTGGTT CAAGAATCGT CGGGCCAAAT GGAGAAAGAG GGAGCGCAAC
CAGCAGGCCG AGCTATGCAA GAATGGCTTC GGGCCGCAGT TCAATGGGCT CATGCAGCCC
TACGACGACA TGTACCCAGG CTATTCCTAC AACAACTGGG CCGCCAAGGG CCTTACATCC
GCCTCCCTAT CCACCAAGAG CTTCCCCTTC TTCAACTCTA TGAACGTCAA CCCCCTGTCA
TCACAGAGCA TGTTTTCCCC ACCCAACTCT ATCTCGTCCA TGAGCATGTC GTCCAGCATG
GTGCCCTCAG CAGTGACAGG CGTCCCGGGC TCCAGTCTCA ACAGCCTGAA TAACTTGAAC
AACCTGAGTA GCCCGTCGCT GAATTCCGCG GTGCCGACGC CTGCCTGTCC TTACGCGCCG
CCGACTCCTC CGTATGTTTA TAGGGACACG TGTAACTCGA GCCTGGCCAG CCTGAGACTG
AAAGCAAAGC AGCACTCCAG CTTCGGCTAC GCCAGCGTGC AGAACCCGGC CTCCAACCTG
AGTGCTTGCC AGTATGCAGT GGACCGGCCC GTGTGA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq NP_001191328.1
CDS216..1031
Misc Feature(1)207..209(+)
Misc Feature(2)333..509(+)
Misc Feature(3)333..503(+)
Misc Feature(4)339..491(+)
Misc Feature(5)897..953(+)
Exon (1)1..205
Gene:PITX2
Gene Synonym:
Exon (2)206..261
Gene:PITX2
Gene Synonym:
Exon (3)262..467
Gene:PITX2
Gene Synonym:
Exon (4)468..1733
Gene:PITX2
Gene Synonym:
Translation

Target ORF information:

RefSeq Version NM_001204399
Organism Homo sapiens (human)
Definition Homo sapiens paired-like homeodomain 2 (PITX2), transcript variant 6, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
NM_001204399

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
ATGGAGACCA ACTGCCGCAA ACTGGTGTCG GCGTGTGTGC AATTAGAGAA AGATAAAAGC 
CAGCAGGGGA AGAATGAGGA CGTGGGCGCC GAGGACCCGT CTAAGAAGAA GCGGCAAAGG
CGGCAGCGGA CTCACTTTAC CAGCCAGCAG CTCCAGGAGC TGGAGGCCAC TTTCCAGAGG
AACCGCTACC CGGACATGTC CACACGCGAA GAAATCGCTG TGTGGACCAA CCTTACGGAA
GCCCGAGTCC GGGTTTGGTT CAAGAATCGT CGGGCCAAAT GGAGAAAGAG GGAGCGCAAC
CAGCAGGCCG AGCTATGCAA GAATGGCTTC GGGCCGCAGT TCAATGGGCT CATGCAGCCC
TACGACGACA TGTACCCAGG CTATTCCTAC AACAACTGGG CCGCCAAGGG CCTTACATCC
GCCTCCCTAT CCACCAAGAG CTTCCCCTTC TTCAACTCTA TGAACGTCAA CCCCCTGTCA
TCACAGAGCA TGTTTTCCCC ACCCAACTCT ATCTCGTCCA TGAGCATGTC GTCCAGCATG
GTGCCCTCAG CAGTGACAGG CGTCCCGGGC TCCAGTCTCA ACAGCCTGAA TAACTTGAAC
AACCTGAGTA GCCCGTCGCT GAATTCCGCG GTGCCGACGC CTGCCTGTCC TTACGCGCCG
CCGACTCCTC CGTATGTTTA TAGGGACACG TGTAACTCGA GCCTGGCCAG CCTGAGACTG
AAAGCAAAGC AGCACTCCAG CTTCGGCTAC GCCAGCGTGC AGAACCCGGC CTCCAACCTG
AGTGCTTGCC AGTATGCAGT GGACCGGCCC GTGTGA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OHu17508
Clone ID Related Accession (Same CDS sequence) NM_001204397 , NM_001204398 , NM_153426 , XM_006714235
Accession Version NM_153426.2 Documents for ORF clone product in dufault vector
Sequence Information ORF Nucleotide Sequence (Length: 954bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ® Seamless cloning technology
Structure linear
Update Date 15-MAR-2015
Organism Homo sapiens (human)
Product pituitary homeobox 2 isoform b
Comment REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from BP372081.1, AK127829.1, BX380370.2, U69961.1, BC106010.1 and BC013998.2. On or before Aug 31, 2013 this sequence version replaced gi:530377830, gi:24234707. Transcript Variant: This variant (2), also known as ARP1b, encodes the predominant isoform (b). Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## CDS exon combination :: AF048721.1, AK127829.1 [ECO:0000331] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
ATGGAGACCA ACTGCCGCAA ACTGGTGTCG GCGTGTGTGC AATTAGGCGT GCAGCCGGCG 
GCCGTTGAAT GTCTCTTCTC CAAAGACTCC GAAATCAAAA AGGTCGAGTT CACGGACTCT
CCTGAGAGCC GAAAAGAGGC AGCCAGCAGC AAGTTCTTCC CGCGGCAGCA TCCTGGCGCC
AATGAGAAAG ATAAAAGCCA GCAGGGGAAG AATGAGGACG TGGGCGCCGA GGACCCGTCT
AAGAAGAAGC GGCAAAGGCG GCAGCGGACT CACTTTACCA GCCAGCAGCT CCAGGAGCTG
GAGGCCACTT TCCAGAGGAA CCGCTACCCG GACATGTCCA CACGCGAAGA AATCGCTGTG
TGGACCAACC TTACGGAAGC CCGAGTCCGG GTTTGGTTCA AGAATCGTCG GGCCAAATGG
AGAAAGAGGG AGCGCAACCA GCAGGCCGAG CTATGCAAGA ATGGCTTCGG GCCGCAGTTC
AATGGGCTCA TGCAGCCCTA CGACGACATG TACCCAGGCT ATTCCTACAA CAACTGGGCC
GCCAAGGGCC TTACATCCGC CTCCCTATCC ACCAAGAGCT TCCCCTTCTT CAACTCTATG
AACGTCAACC CCCTGTCATC ACAGAGCATG TTTTCCCCAC CCAACTCTAT CTCGTCCATG
AGCATGTCGT CCAGCATGGT GCCCTCAGCA GTGACAGGCG TCCCGGGCTC CAGTCTCAAC
AGCCTGAATA ACTTGAACAA CCTGAGTAGC CCGTCGCTGA ATTCCGCGGT GCCGACGCCT
GCCTGTCCTT ACGCGCCGCC GACTCCTCCG TATGTTTATA GGGACACGTG TAACTCGAGC
CTGGCCAGCC TGAGACTGAA AGCAAAGCAG CACTCCAGCT TCGGCTACGC CAGCGTGCAG
AACCCGGCCT CCAACCTGAG TGCTTGCCAG TATGCAGTGG ACCGGCCCGT GTGA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq NP_700475.1
CDS1590..2543
Misc Feature(1)1581..1583(+)
Misc Feature(2)1845..2021(+)
Misc Feature(3)1845..2015(+)
Misc Feature(4)1851..2003(+)
Misc Feature(5)2409..2465(+)
Misc Feature(6)2424..2465(+)
Misc Feature(7)2442..2456(+)
Exon (1)1..205
Gene:PITX2
Gene Synonym:
Exon (2)206..1579
Gene:PITX2
Gene Synonym:
Exon (3)1580..1635
Gene:PITX2
Gene Synonym:
Exon (4)1636..1773
Gene:PITX2
Gene Synonym:
Exon (5)1774..1979
Gene:PITX2
Gene Synonym:
Exon (6)1980..3245
Gene:PITX2
Gene Synonym:
Translation

Target ORF information:

RefSeq Version NM_153426
Organism Homo sapiens (human)
Definition Homo sapiens paired-like homeodomain 2 (PITX2), transcript variant 2, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
NM_153426

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
ATGGAGACCA ACTGCCGCAA ACTGGTGTCG GCGTGTGTGC AATTAGGCGT GCAGCCGGCG 
GCCGTTGAAT GTCTCTTCTC CAAAGACTCC GAAATCAAAA AGGTCGAGTT CACGGACTCT
CCTGAGAGCC GAAAAGAGGC AGCCAGCAGC AAGTTCTTCC CGCGGCAGCA TCCTGGCGCC
AATGAGAAAG ATAAAAGCCA GCAGGGGAAG AATGAGGACG TGGGCGCCGA GGACCCGTCT
AAGAAGAAGC GGCAAAGGCG GCAGCGGACT CACTTTACCA GCCAGCAGCT CCAGGAGCTG
GAGGCCACTT TCCAGAGGAA CCGCTACCCG GACATGTCCA CACGCGAAGA AATCGCTGTG
TGGACCAACC TTACGGAAGC CCGAGTCCGG GTTTGGTTCA AGAATCGTCG GGCCAAATGG
AGAAAGAGGG AGCGCAACCA GCAGGCCGAG CTATGCAAGA ATGGCTTCGG GCCGCAGTTC
AATGGGCTCA TGCAGCCCTA CGACGACATG TACCCAGGCT ATTCCTACAA CAACTGGGCC
GCCAAGGGCC TTACATCCGC CTCCCTATCC ACCAAGAGCT TCCCCTTCTT CAACTCTATG
AACGTCAACC CCCTGTCATC ACAGAGCATG TTTTCCCCAC CCAACTCTAT CTCGTCCATG
AGCATGTCGT CCAGCATGGT GCCCTCAGCA GTGACAGGCG TCCCGGGCTC CAGTCTCAAC
AGCCTGAATA ACTTGAACAA CCTGAGTAGC CCGTCGCTGA ATTCCGCGGT GCCGACGCCT
GCCTGTCCTT ACGCGCCGCC GACTCCTCCG TATGTTTATA GGGACACGTG TAACTCGAGC
CTGGCCAGCC TGAGACTGAA AGCAAAGCAG CACTCCAGCT TCGGCTACGC CAGCGTGCAG
AACCCGGCCT CCAACCTGAG TGCTTGCCAG TATGCAGTGG ACCGGCCCGT GTGA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OHu17480
Clone ID Related Accession (Same CDS sequence) NM_001204399 , NM_153427 , XM_011532027
Accession Version NM_153427.2 Documents for ORF clone product in dufault vector
Sequence Information ORF Nucleotide Sequence (Length: 816bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags COA
ORF Insert Method CloneEZ® Seamless cloning technology
Structure linear
Update Date 15-MAR-2015
Organism Homo sapiens (human)
Product pituitary homeobox 2 isoform a
Comment REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from BP372081.1, AK127829.1, BX380370.2, U69961.1 and BC106010.1. This sequence is a reference standard in the RefSeqGene project. On Mar 1, 2011 this sequence version replaced gi:24234710. Transcript Variant: This variant (1), also known as ARP1a, lacks an in-frame exon in the 5' region, as compared to variant 2. The resulting isoform (a) lacks an internal segment, as compared to isoform b. Variants 1 and 6 encode the same isoform a. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## CDS exon combination :: U69961.1, AF048720.1 [ECO:0000331] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

1
61
121
181
241
301
361
421
481
541
601
661
721
781
ATGGAGACCA ACTGCCGCAA ACTGGTGTCG GCGTGTGTGC AATTAGAGAA AGATAAAAGC 
CAGCAGGGGA AGAATGAGGA CGTGGGCGCC GAGGACCCGT CTAAGAAGAA GCGGCAAAGG
CGGCAGCGGA CTCACTTTAC CAGCCAGCAG CTCCAGGAGC TGGAGGCCAC TTTCCAGAGG
AACCGCTACC CGGACATGTC CACACGCGAA GAAATCGCTG TGTGGACCAA CCTTACGGAA
GCCCGAGTCC GGGTTTGGTT CAAGAATCGT CGGGCCAAAT GGAGAAAGAG GGAGCGCAAC
CAGCAGGCCG AGCTATGCAA GAATGGCTTC GGGCCGCAGT TCAATGGGCT CATGCAGCCC
TACGACGACA TGTACCCAGG CTATTCCTAC AACAACTGGG CCGCCAAGGG CCTTACATCC
GCCTCCCTAT CCACCAAGAG CTTCCCCTTC TTCAACTCTA TGAACGTCAA CCCCCTGTCA
TCACAGAGCA TGTTTTCCCC ACCCAACTCT ATCTCGTCCA TGAGCATGTC GTCCAGCATG
GTGCCCTCAG CAGTGACAGG CGTCCCGGGC TCCAGTCTCA ACAGCCTGAA TAACTTGAAC
AACCTGAGTA GCCCGTCGCT GAATTCCGCG GTGCCGACGC CTGCCTGTCC TTACGCGCCG
CCGACTCCTC CGTATGTTTA TAGGGACACG TGTAACTCGA GCCTGGCCAG CCTGAGACTG
AAAGCAAAGC AGCACTCCAG CTTCGGCTAC GCCAGCGTGC AGAACCCGGC CTCCAACCTG
AGTGCTTGCC AGTATGCAGT GGACCGGCCC GTGTGA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq NP_700476.1
CDS1590..2405
Misc Feature(1)1581..1583(+)
Misc Feature(2)1707..1883(+)
Misc Feature(3)1707..1877(+)
Misc Feature(4)1713..1865(+)
Misc Feature(5)2271..2327(+)
Exon (1)1..205
Gene:PITX2
Gene Synonym:
Exon (2)206..1579
Gene:PITX2
Gene Synonym:
Exon (3)1580..1635
Gene:PITX2
Gene Synonym:
Exon (4)1636..1841
Gene:PITX2
Gene Synonym:
Exon (5)1842..3107
Gene:PITX2
Gene Synonym:
Translation

Target ORF information:

RefSeq Version NM_153427
Organism Homo sapiens (human)
Definition Homo sapiens paired-like homeodomain 2 (PITX2), transcript variant 1, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
NM_153427

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
ATGGAGACCA ACTGCCGCAA ACTGGTGTCG GCGTGTGTGC AATTAGAGAA AGATAAAAGC 
CAGCAGGGGA AGAATGAGGA CGTGGGCGCC GAGGACCCGT CTAAGAAGAA GCGGCAAAGG
CGGCAGCGGA CTCACTTTAC CAGCCAGCAG CTCCAGGAGC TGGAGGCCAC TTTCCAGAGG
AACCGCTACC CGGACATGTC CACACGCGAA GAAATCGCTG TGTGGACCAA CCTTACGGAA
GCCCGAGTCC GGGTTTGGTT CAAGAATCGT CGGGCCAAAT GGAGAAAGAG GGAGCGCAAC
CAGCAGGCCG AGCTATGCAA GAATGGCTTC GGGCCGCAGT TCAATGGGCT CATGCAGCCC
TACGACGACA TGTACCCAGG CTATTCCTAC AACAACTGGG CCGCCAAGGG CCTTACATCC
GCCTCCCTAT CCACCAAGAG CTTCCCCTTC TTCAACTCTA TGAACGTCAA CCCCCTGTCA
TCACAGAGCA TGTTTTCCCC ACCCAACTCT ATCTCGTCCA TGAGCATGTC GTCCAGCATG
GTGCCCTCAG CAGTGACAGG CGTCCCGGGC TCCAGTCTCA ACAGCCTGAA TAACTTGAAC
AACCTGAGTA GCCCGTCGCT GAATTCCGCG GTGCCGACGC CTGCCTGTCC TTACGCGCCG
CCGACTCCTC CGTATGTTTA TAGGGACACG TGTAACTCGA GCCTGGCCAG CCTGAGACTG
AAAGCAAAGC AGCACTCCAG CTTCGGCTAC GCCAGCGTGC AGAACCCGGC CTCCAACCTG
AGTGCTTGCC AGTATGCAGT GGACCGGCCC GTGTGA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OHu17360
Clone ID Related Accession (Same CDS sequence) NM_000325
Accession Version NM_000325.5 Documents for ORF clone product in dufault vector
Sequence Information ORF Nucleotide Sequence (Length: 975bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags COA
ORF Insert Method CloneEZ® Seamless cloning technology
Structure linear
Update Date 15-MAR-2015
Organism Homo sapiens (human)
Product pituitary homeobox 2 isoform c
Comment REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AC017068.7 and BC013998.2. On Jul 24, 2007 this sequence version replaced gi:40316913. Transcript Variant: This variant (3), also known as ARP1c, lacks several exons at the 5' end and has an alternate 5' exon, as compared to variant 2. The resulting isoform (c) has a longer and distinct N-terminus, as compared to isoform b. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC013998.2, AK313987.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2162568 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
ATGAACTGCA TGAAAGGCCC GCTTCACTTG GAGCACCGAG CAGCGGGGAC CAAGCTGTCG 
GCCGTCTCCT CATCTTCCTG TCACCATCCC CAGCCGTTAG CCATGGCTTC GGTTCTGGCT
CCCGGTCAGC CCCGGTCGCT GGACTCCTCC AAGCACAGGC TGGAGGTGCA CACCATCTCC
GACACCTCCA GCCCGGAGGC CGCAGAGAAA GATAAAAGCC AGCAGGGGAA GAATGAGGAC
GTGGGCGCCG AGGACCCGTC TAAGAAGAAG CGGCAAAGGC GGCAGCGGAC TCACTTTACC
AGCCAGCAGC TCCAGGAGCT GGAGGCCACT TTCCAGAGGA ACCGCTACCC GGACATGTCC
ACACGCGAAG AAATCGCTGT GTGGACCAAC CTTACGGAAG CCCGAGTCCG GGTTTGGTTC
AAGAATCGTC GGGCCAAATG GAGAAAGAGG GAGCGCAACC AGCAGGCCGA GCTATGCAAG
AATGGCTTCG GGCCGCAGTT CAATGGGCTC ATGCAGCCCT ACGACGACAT GTACCCAGGC
TATTCCTACA ACAACTGGGC CGCCAAGGGC CTTACATCCG CCTCCCTATC CACCAAGAGC
TTCCCCTTCT TCAACTCTAT GAACGTCAAC CCCCTGTCAT CACAGAGCAT GTTTTCCCCA
CCCAACTCTA TCTCGTCCAT GAGCATGTCG TCCAGCATGG TGCCCTCAGC AGTGACAGGC
GTCCCGGGCT CCAGTCTCAA CAGCCTGAAT AACTTGAACA ACCTGAGTAG CCCGTCGCTG
AATTCCGCGG TGCCGACGCC TGCCTGTCCT TACGCGCCGC CGACTCCTCC GTATGTTTAT
AGGGACACGT GTAACTCGAG CCTGGCCAGC CTGAGACTGA AAGCAAAGCA GCACTCCAGC
TTCGGCTACG CCAGCGTGCA GAACCCGGCC TCCAACCTGA GTGCTTGCCA GTATGCAGTG
GACCGGCCCG TGTGA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq NP_000316.2
CDS639..1613
Misc Feature(1)429..431(+)
Misc Feature(2)810..812(+)
Misc Feature(3)816..818(+)
Misc Feature(4)822..824(+)
Misc Feature(5)825..827(+)
Misc Feature(6)828..830(+)
Misc Feature(7)915..1091(+)
Misc Feature(8)915..1085(+)
Misc Feature(9)921..1073(+)
Misc Feature(10)1479..1535(+)
Exon (1)1..843
Gene:PITX2
Gene Synonym:
Exon (2)844..1049
Gene:PITX2
Gene Synonym:
Exon (3)1050..2315
Gene:PITX2
Gene Synonym:
Translation

Target ORF information:

RefSeq Version NM_000325
Organism Homo sapiens (human)
Definition Homo sapiens paired-like homeodomain 2 (PITX2), transcript variant 3, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
NM_000325

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
ATGAACTGCA TGAAAGGCCC GCTTCACTTG GAGCACCGAG CAGCGGGGAC CAAGCTGTCG 
GCCGTCTCCT CATCTTCCTG TCACCATCCC CAGCCGTTAG CCATGGCTTC GGTTCTGGCT
CCCGGTCAGC CCCGGTCGCT GGACTCCTCC AAGCACAGGC TGGAGGTGCA CACCATCTCC
GACACCTCCA GCCCGGAGGC CGCAGAGAAA GATAAAAGCC AGCAGGGGAA GAATGAGGAC
GTGGGCGCCG AGGACCCGTC TAAGAAGAAG CGGCAAAGGC GGCAGCGGAC TCACTTTACC
AGCCAGCAGC TCCAGGAGCT GGAGGCCACT TTCCAGAGGA ACCGCTACCC GGACATGTCC
ACACGCGAAG AAATCGCTGT GTGGACCAAC CTTACGGAAG CCCGAGTCCG GGTTTGGTTC
AAGAATCGTC GGGCCAAATG GAGAAAGAGG GAGCGCAACC AGCAGGCCGA GCTATGCAAG
AATGGCTTCG GGCCGCAGTT CAATGGGCTC ATGCAGCCCT ACGACGACAT GTACCCAGGC
TATTCCTACA ACAACTGGGC CGCCAAGGGC CTTACATCCG CCTCCCTATC CACCAAGAGC
TTCCCCTTCT TCAACTCTAT GAACGTCAAC CCCCTGTCAT CACAGAGCAT GTTTTCCCCA
CCCAACTCTA TCTCGTCCAT GAGCATGTCG TCCAGCATGG TGCCCTCAGC AGTGACAGGC
GTCCCGGGCT CCAGTCTCAA CAGCCTGAAT AACTTGAACA ACCTGAGTAG CCCGTCGCTG
AATTCCGCGG TGCCGACGCC TGCCTGTCCT TACGCGCCGC CGACTCCTCC GTATGTTTAT
AGGGACACGT GTAACTCGAG CCTGGCCAGC CTGAGACTGA AAGCAAAGCA GCACTCCAGC
TTCGGCTACG CCAGCGTGCA GAACCCGGCC TCCAACCTGA GTGCTTGCCA GTATGCAGTG
GACCGGCCCG TGTGA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

 
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