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FGFRL1 cDNA ORF clone, Homo sapiens(Human)

Gene Symbol FGFRL1
Entrez Gene ID 53834
Full Name fibroblast growth factor receptor like 1
Synonyms FGFR5,FHFR
General protein information
Preferred Names

fibroblast growth factor receptor like 1

Names

fibroblast growth factor receptor-like 1
FGF homologous factor receptor
FGF receptor-like protein 1
FGFR-5
FGFR-like protein
fibroblast growth factor receptor 5

Gene Type protein-coding
Organism Homo sapiens(Human)
Genome

4

4p16.3

Summary The protein encoded by this gene is a member of the fibroblast growth factor receptor (FGFR) family, where amino acid sequence is highly conserved between members and throughout evolution. FGFR family members differ from one another in their ligand affinities and tissue distribution. A full-length representative protein would consist of an extracellular region, composed of three immunoglobulin-like domains, a single hydrophobic membrane-spanning segment and a cytoplasmic tyrosine kinase domain. The extracellular portion of the protein interacts with fibroblast growth factors, setting in motion a cascade of downstream signals, ultimately influencing mitogenesis and differentiation. A marked difference between this gene product and the other family members is its lack of a cytoplasmic tyrosine kinase domain. The result is a transmembrane receptor that could interact with other family members and potentially inhibit signaling. Multiple alternatively spliced transcript variants encoding the same isoform have been found for this gene. [provided by RefSeq, Jul 2008].
Disorder MIM:

605830


mRNA and Protein(s)

mRNA Protein Name
NM_021923.3 NP_068742.2 fibroblast growth factor receptor-like 1 precursor
NM_001004358.1 NP_001004358.1 fibroblast growth factor receptor-like 1 precursor
NM_001004356.2 NP_001004356.1 fibroblast growth factor receptor-like 1 precursor
XM_011513486.1 XP_011511788.1 fibroblast growth factor receptor-like 1 isoform X1
XM_011513487.1 XP_011511789.1 fibroblast growth factor receptor-like 1 isoform X1



Rattus norvegicus (Norway rat) Fgfrl1 NP_954545.1
Caenorhabditis elegans (roundworm) igcm-4 NP_508377.1
Homo sapiens (human) FGFRL1 NP_068742.2
Bos taurus (cattle) FGFRL1 NP_001192925.1
Danio rerio (zebrafish) fgfrl1a NP_956670.1
Xenopus tropicalis (tropical clawed frog) fgfrl1 NP_001011189.1
Gallus gallus (chicken) FGFRL1 NP_989787.1
Macaca mulatta (rhesus monkey) FGFRL1 XP_001092871.1
Canis lupus familiaris (dog) LOC102151155 XP_005618732.1
Mus musculus (house mouse) Fgfrl1 NP_473412.1


Related articles in PubMed

MicroRNA-210 promotes cancer angiogenesis by targeting fibroblast growth factor receptor-like 1 in hepatocellular carcinoma.
Yang Y, Zhang J, Xia T, Li G, Tian T, Wang M, Wang R, Zhao L, Yang Y, Lan K, Zhou W
Oncology reports36(5)2553-2562(2016 Nov)

Receptor FGFRL1 does not promote cell proliferation but induces cell adhesion.
Yang X, Steinberg F, Zhuang L, Bessey R, Trueb B
International journal of molecular medicine38(1)30-8(2016 Jul)

Cell-cell fusion induced by the Ig3 domain of receptor FGFRL1 in CHO cells.
Zhuang L, Pandey AV, Villiger PM, Trueb B
Biochimica et biophysica acta1853(10 Pt A)2273-85(2015 Oct)

Identification of a novel FGFRL1 MicroRNA target site polymorphism for bone mineral density in meta-analyses of genome-wide association studies.
Niu T, Liu N, Zhao M, Xie G, Zhang L, Li J, Pei YF, Shen H, Fu X, He H, Lu S, Chen XD, Tan LJ, Yang TL, Guo Y, Leo PJ, Duncan EL, Shen J, Guo YF, Nicholson GC, Prince RL, Eisman JA, Jones G, Sambrook PN, Hu X, Das PM, Tian Q, Zhu XZ, Papasian CJ, Brown MA, Uitterlinden AG, Wang YP, Xiang S, Deng HW
Human molecular genetics24(16)4710-27(2015 Aug)

Multistage genome-wide association meta-analyses identified two new loci for bone mineral density.
Zhang L, Choi HJ, Estrada K, Leo PJ, Li J, Pei YF, Zhang Y, Lin Y, Shen H, Liu YZ, Liu Y, Zhao Y, Zhang JG, Tian Q, Wang YP, Han Y, Ran S, Hai R, Zhu XZ, Wu S, Yan H, Liu X, Yang TL, Guo Y, Zhang F, Guo YF, Chen Y, Chen X, Tan L, Zhang L, Deng FY, Deng H, Rivadeneira F, Duncan EL, Lee JY, Han BG, Cho NH, Nicholson GC, McCloskey E, Eastell R, Prince RL, Eisman JA, Jones G, Reid IR, Sambrook PN, Dennison EM, Danoy P, Yerges-Armstrong LM, Streeten EA, Hu T, Xiang S, Papasian CJ, Brown MA, Shin CS, Uitterlinden AG, Deng HW
Human molecular genetics23(7)1923-33(2014 Apr)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

FGFRL1 is a transmembrane receptor that can induce the fusion of CHO cells to multinucleated syncytia. This cell fusion activity has been attributed to the extracellular Ig3 domain of the receptor. The Ig3 domain from humans, mice, chicken and fish stimulates fusion of CHO cells, while the Ig3 domain from lancelet and sea urchin does not.
Title: Evolution of the fusogenic activity of the receptor FGFRL1.

Both in vitro and in vivo studies determined that miR-210 promoted hepatocellular carcinoma (HCC), angiogenesis, and the corresponding mechanism was identified to be the direct targeting and inhibition of fibroblast growth factor receptor-like 1 (FGFRL1) expression
Title: MicroRNA-210 promotes cancer angiogenesis by targeting fibroblast growth factor receptor-like 1 in hepatocellular carcinoma.

FGFRL1 is a cell adhesion protein.
Title: Receptor FGFRL1 does not promote cell proliferation but induces cell adhesion.

Cell-cell fusion induced by the Ig3 domain of receptor FGFRL1
Title: Cell-cell fusion induced by the Ig3 domain of receptor FGFRL1 in CHO cells.

functional evidence for a novel FGFRL1 poly-miRTS rs4647940 in a previously known 4p16.3 locus, and experimental and clinical genetics studies have shown both FGFRL1 and hsa-miR-140-5p are important for bone formation.
Title: Identification of a novel FGFRL1 MicroRNA target site polymorphism for bone mineral density in meta-analyses of genome-wide association studies.

The following FGFRL1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the FGFRL1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

Online Only Promotion

Up to 50% OFF! Starting
from $49/clone

***CloneID RefSeq Accession Definition **Vector *Turnaround time Price (USD) Select
OHu03560 NM_001004356.2
Latest version!
Homo sapiens fibroblast growth factor receptor-like 1 (FGFRL1), transcript variant 1, mRNA. pcDNA3.1+/C-(K)DYK or customized vector
in pcDNA3.1+/C-(K)DYK
$189.50-$265.30
$379.00
OHu03560 NM_021923.3
Latest version!
Homo sapiens fibroblast growth factor receptor-like 1 (FGFRL1), transcript variant 3, mRNA. pcDNA3.1+/C-(K)DYK or customized vector
in pcDNA3.1+/C-(K)DYK
$189.50-$265.30
$379.00
OHu03560 NM_001004358.1
Latest version!
Homo sapiens fibroblast growth factor receptor-like 1 (FGFRL1), transcript variant 2, mRNA. pcDNA3.1+/C-(K)DYK or customized vector
in pcDNA3.1+/C-(K)DYK
$189.50-$265.30
$379.00
OHu03560 XM_011513486.1
Latest version!
Homo sapiens fibroblast growth factor receptor-like 1 (FGFRL1), transcript variant X1, mRNA. pcDNA3.1+/C-(K)DYK or customized vector
in pcDNA3.1+/C-(K)DYK
$189.50-$265.30
$379.00
OHu03560 XM_011513487.1
Latest version!
Homo sapiens fibroblast growth factor receptor-like 1 (FGFRL1), transcript variant X2, mRNA. pcDNA3.1+/C-(K)DYK or customized vector
in pcDNA3.1+/C-(K)DYK
$189.50-$265.30
$379.00

ORF Online Only Promotion

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.


CloneID OHu03560
Clone ID Related Accession (Same CDS sequence) NM_021923.3 , NM_001004358.1 , NM_001004356.2 , XM_011513486.1 , XM_011513487.1
Accession Version NM_021923.3 Latest version! Documents for ORF clone product in dufault vector
Sequence Information ORF Nucleotide Sequence (Length: 1515bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags COA
ORF Insert Method CloneEZ® Seamless cloning technology
Insert Structure linear
Update Date 2017-04-26
Organism Homo sapiens(Human)
Product fibroblast growth factor receptor-like 1 precursor
Comment REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AJ277437.1, BC036769.1 and BC013955.2. On Sep 13, 2004 this sequence version replaced NM_021923.2. Transcript Variant: This variant (3) has an alternate 5' UTR, and encodes the same isoform, as compared to variant 1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AJ277437.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1968540, SAMEA1968832 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

1
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361
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481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
1501
ATGACGCCGA GCCCCCTGTT GCTGCTCCTG CTGCCGCCGC TGCTGCTGGG GGCCTTCCCG 
CCGGCCGCCG CCGCCCGAGG CCCCCCAAAG ATGGCGGACA AGGTGGTCCC ACGGCAGGTG
GCCCGGCTGG GCCGCACTGT GCGGCTGCAG TGCCCAGTGG AGGGGGACCC GCCGCCGCTG
ACCATGTGGA CCAAGGATGG CCGCACCATC CACAGCGGCT GGAGCCGCTT CCGCGTGCTG
CCGCAGGGGC TGAAGGTGAA GCAGGTGGAG CGGGAGGATG CCGGCGTGTA CGTGTGCAAG
GCCACCAACG GCTTCGGCAG CCTGAGCGTC AACTACACCC TCGTCGTGCT GGATGACATT
AGCCCAGGGA AGGAGAGCCT GGGGCCCGAC AGCTCCTCTG GGGGTCAAGA GGACCCCGCC
AGCCAGCAGT GGGCACGACC GCGCTTCACA CAGCCCTCCA AGATGAGGCG CCGGGTGATC
GCACGGCCCG TGGGTAGCTC CGTGCGGCTC AAGTGCGTGG CCAGCGGGCA CCCTCGGCCC
GACATCACGT GGATGAAGGA CGACCAGGCC TTGACGCGCC CAGAGGCCGC TGAGCCCAGG
AAGAAGAAGT GGACACTGAG CCTGAAGAAC CTGCGGCCGG AGGACAGCGG CAAATACACC
TGCCGCGTGT CGAACCGCGC GGGCGCCATC AACGCCACCT ACAAGGTGGA TGTGATCCAG
CGGACCCGTT CCAAGCCCGT GCTCACAGGC ACGCACCCCG TGAACACGAC GGTGGACTTC
GGGGGGACCA CGTCCTTCCA GTGCAAGGTG CGCAGCGACG TGAAGCCGGT GATCCAGTGG
CTGAAGCGCG TGGAGTACGG CGCCGAGGGC CGCCACAACT CCACCATCGA TGTGGGCGGC
CAGAAGTTTG TGGTGCTGCC CACGGGTGAC GTGTGGTCGC GGCCCGACGG CTCCTACCTC
AATAAGCTGC TCATCACCCG TGCCCGCCAG GACGATGCGG GCATGTACAT CTGCCTTGGC
GCCAACACCA TGGGCTACAG CTTCCGCAGC GCCTTCCTCA CCGTGCTGCC AGACCCAAAA
CCGCCAGGGC CACCTGTGGC CTCCTCGTCC TCGGCCACTA GCCTGCCGTG GCCCGTGGTC
ATCGGCATCC CAGCCGGCGC TGTCTTCATC CTGGGCACCC TGCTCCTGTG GCTTTGCCAG
GCCCAGAAGA AGCCGTGCAC CCCCGCGCCT GCCCCTCCCC TGCCTGGGCA CCGCCCGCCG
GGGACGGCCC GCGACCGCAG CGGAGACAAG GACCTTCCCT CGTTGGCCGC CCTCAGCGCT
GGCCCTGGTG TGGGGCTGTG TGAGGAGCAT GGGTCTCCGG CAGCCCCCCA GCACTTACTG
GGCCCAGGCC CAGTTGCTGG CCCTAAGTTG TACCCCAAAC TCTACACAGA CATCCACACA
CACACACACA CACACTCTCA CACACACTCA CACGTGGAGG GCAAGGTCCA CCAGCACATC
CACTATCAGT GCTAG

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq NP_068742.2
CDS23..1537
Misc Feature(1)119..370
Misc Feature(2)152..340
Misc Feature(3)461..736
Misc Feature(4)491..736
Misc Feature(5)order(497..499,503..505,509..511)
Misc Feature(6)order(500..502,521..529,533..535)
Misc Feature(7)779..1087
Misc Feature(8)803..1090
Misc Feature(9)1157..1219
Exon (1)1..101
Exon (2)102..374
Exon (3)375..455
Exon (4)456..740
Exon (5)741..1094
Exon (6)1095..3088
Translation

Target ORF information:

RefSeq Version NM_021923.3
Organism Homo sapiens(Human)
Definition Homo sapiens fibroblast growth factor receptor-like 1 (FGFRL1), transcript variant 3, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
NM_021923.3

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
1501
ATGACGCCGA GCCCCCTGTT GCTGCTCCTG CTGCCGCCGC TGCTGCTGGG GGCCTTCCCG 
CCGGCCGCCG CCGCCCGAGG CCCCCCAAAG ATGGCGGACA AGGTGGTCCC ACGGCAGGTG
GCCCGGCTGG GCCGCACTGT GCGGCTGCAG TGCCCAGTGG AGGGGGACCC GCCGCCGCTG
ACCATGTGGA CCAAGGATGG CCGCACCATC CACAGCGGCT GGAGCCGCTT CCGCGTGCTG
CCGCAGGGGC TGAAGGTGAA GCAGGTGGAG CGGGAGGATG CCGGCGTGTA CGTGTGCAAG
GCCACCAACG GCTTCGGCAG CCTGAGCGTC AACTACACCC TCGTCGTGCT GGATGACATT
AGCCCAGGGA AGGAGAGCCT GGGGCCCGAC AGCTCCTCTG GGGGTCAAGA GGACCCCGCC
AGCCAGCAGT GGGCACGACC GCGCTTCACA CAGCCCTCCA AGATGAGGCG CCGGGTGATC
GCACGGCCCG TGGGTAGCTC CGTGCGGCTC AAGTGCGTGG CCAGCGGGCA CCCTCGGCCC
GACATCACGT GGATGAAGGA CGACCAGGCC TTGACGCGCC CAGAGGCCGC TGAGCCCAGG
AAGAAGAAGT GGACACTGAG CCTGAAGAAC CTGCGGCCGG AGGACAGCGG CAAATACACC
TGCCGCGTGT CGAACCGCGC GGGCGCCATC AACGCCACCT ACAAGGTGGA TGTGATCCAG
CGGACCCGTT CCAAGCCCGT GCTCACAGGC ACGCACCCCG TGAACACGAC GGTGGACTTC
GGGGGGACCA CGTCCTTCCA GTGCAAGGTG CGCAGCGACG TGAAGCCGGT GATCCAGTGG
CTGAAGCGCG TGGAGTACGG CGCCGAGGGC CGCCACAACT CCACCATCGA TGTGGGCGGC
CAGAAGTTTG TGGTGCTGCC CACGGGTGAC GTGTGGTCGC GGCCCGACGG CTCCTACCTC
AATAAGCTGC TCATCACCCG TGCCCGCCAG GACGATGCGG GCATGTACAT CTGCCTTGGC
GCCAACACCA TGGGCTACAG CTTCCGCAGC GCCTTCCTCA CCGTGCTGCC AGACCCAAAA
CCGCCAGGGC CACCTGTGGC CTCCTCGTCC TCGGCCACTA GCCTGCCGTG GCCCGTGGTC
ATCGGCATCC CAGCCGGCGC TGTCTTCATC CTGGGCACCC TGCTCCTGTG GCTTTGCCAG
GCCCAGAAGA AGCCGTGCAC CCCCGCGCCT GCCCCTCCCC TGCCTGGGCA CCGCCCGCCG
GGGACGGCCC GCGACCGCAG CGGAGACAAG GACCTTCCCT CGTTGGCCGC CCTCAGCGCT
GGCCCTGGTG TGGGGCTGTG TGAGGAGCAT GGGTCTCCGG CAGCCCCCCA GCACTTACTG
GGCCCAGGCC CAGTTGCTGG CCCTAAGTTG TACCCCAAAC TCTACACAGA CATCCACACA
CACACACACA CACACTCTCA CACACACTCA CACGTGGAGG GCAAGGTCCA CCAGCACATC
CACTATCAGT GCTAG

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OHu03560
Clone ID Related Accession (Same CDS sequence) NM_021923.3 , NM_001004358.1 , NM_001004356.2 , XM_011513486.1 , XM_011513487.1
Accession Version NM_001004358.1 Latest version! Documents for ORF clone product in dufault vector
Sequence Information ORF Nucleotide Sequence (Length: 1515bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags COA
ORF Insert Method CloneEZ® Seamless cloning technology
Insert Structure linear
Update Date 2017-04-26
Organism Homo sapiens(Human)
Product fibroblast growth factor receptor-like 1 precursor
Comment REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AF279689.1, BC036769.1 and BC013955.2. Transcript Variant: This variant (2) has an alternate 5' UTR, and encodes the same isoform, as compared to variant 1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AF279689.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2154125, SAMEA2154405 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
1501
ATGACGCCGA GCCCCCTGTT GCTGCTCCTG CTGCCGCCGC TGCTGCTGGG GGCCTTCCCG 
CCGGCCGCCG CCGCCCGAGG CCCCCCAAAG ATGGCGGACA AGGTGGTCCC ACGGCAGGTG
GCCCGGCTGG GCCGCACTGT GCGGCTGCAG TGCCCAGTGG AGGGGGACCC GCCGCCGCTG
ACCATGTGGA CCAAGGATGG CCGCACCATC CACAGCGGCT GGAGCCGCTT CCGCGTGCTG
CCGCAGGGGC TGAAGGTGAA GCAGGTGGAG CGGGAGGATG CCGGCGTGTA CGTGTGCAAG
GCCACCAACG GCTTCGGCAG CCTGAGCGTC AACTACACCC TCGTCGTGCT GGATGACATT
AGCCCAGGGA AGGAGAGCCT GGGGCCCGAC AGCTCCTCTG GGGGTCAAGA GGACCCCGCC
AGCCAGCAGT GGGCACGACC GCGCTTCACA CAGCCCTCCA AGATGAGGCG CCGGGTGATC
GCACGGCCCG TGGGTAGCTC CGTGCGGCTC AAGTGCGTGG CCAGCGGGCA CCCTCGGCCC
GACATCACGT GGATGAAGGA CGACCAGGCC TTGACGCGCC CAGAGGCCGC TGAGCCCAGG
AAGAAGAAGT GGACACTGAG CCTGAAGAAC CTGCGGCCGG AGGACAGCGG CAAATACACC
TGCCGCGTGT CGAACCGCGC GGGCGCCATC AACGCCACCT ACAAGGTGGA TGTGATCCAG
CGGACCCGTT CCAAGCCCGT GCTCACAGGC ACGCACCCCG TGAACACGAC GGTGGACTTC
GGGGGGACCA CGTCCTTCCA GTGCAAGGTG CGCAGCGACG TGAAGCCGGT GATCCAGTGG
CTGAAGCGCG TGGAGTACGG CGCCGAGGGC CGCCACAACT CCACCATCGA TGTGGGCGGC
CAGAAGTTTG TGGTGCTGCC CACGGGTGAC GTGTGGTCGC GGCCCGACGG CTCCTACCTC
AATAAGCTGC TCATCACCCG TGCCCGCCAG GACGATGCGG GCATGTACAT CTGCCTTGGC
GCCAACACCA TGGGCTACAG CTTCCGCAGC GCCTTCCTCA CCGTGCTGCC AGACCCAAAA
CCGCCAGGGC CACCTGTGGC CTCCTCGTCC TCGGCCACTA GCCTGCCGTG GCCCGTGGTC
ATCGGCATCC CAGCCGGCGC TGTCTTCATC CTGGGCACCC TGCTCCTGTG GCTTTGCCAG
GCCCAGAAGA AGCCGTGCAC CCCCGCGCCT GCCCCTCCCC TGCCTGGGCA CCGCCCGCCG
GGGACGGCCC GCGACCGCAG CGGAGACAAG GACCTTCCCT CGTTGGCCGC CCTCAGCGCT
GGCCCTGGTG TGGGGCTGTG TGAGGAGCAT GGGTCTCCGG CAGCCCCCCA GCACTTACTG
GGCCCAGGCC CAGTTGCTGG CCCTAAGTTG TACCCCAAAC TCTACACAGA CATCCACACA
CACACACACA CACACTCTCA CACACACTCA CACGTGGAGG GCAAGGTCCA CCAGCACATC
CACTATCAGT GCTAG

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq NP_001004358.1
CDS33..1547
Misc Feature(1)129..380
Misc Feature(2)162..350
Misc Feature(3)471..746
Misc Feature(4)501..746
Misc Feature(5)order(507..509,513..515,519..521)
Misc Feature(6)order(510..512,531..539,543..545)
Misc Feature(7)789..1097
Misc Feature(8)813..1100
Misc Feature(9)1167..1229
Exon (1)1..16
Exon (2)17..111
Exon (3)112..384
Exon (4)385..465
Exon (5)466..750
Exon (6)751..1104
Exon (7)1105..3098
Translation

Target ORF information:

RefSeq Version NM_001004358.1
Organism Homo sapiens(Human)
Definition Homo sapiens fibroblast growth factor receptor-like 1 (FGFRL1), transcript variant 2, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
NM_001004358.1

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
1501
ATGACGCCGA GCCCCCTGTT GCTGCTCCTG CTGCCGCCGC TGCTGCTGGG GGCCTTCCCG 
CCGGCCGCCG CCGCCCGAGG CCCCCCAAAG ATGGCGGACA AGGTGGTCCC ACGGCAGGTG
GCCCGGCTGG GCCGCACTGT GCGGCTGCAG TGCCCAGTGG AGGGGGACCC GCCGCCGCTG
ACCATGTGGA CCAAGGATGG CCGCACCATC CACAGCGGCT GGAGCCGCTT CCGCGTGCTG
CCGCAGGGGC TGAAGGTGAA GCAGGTGGAG CGGGAGGATG CCGGCGTGTA CGTGTGCAAG
GCCACCAACG GCTTCGGCAG CCTGAGCGTC AACTACACCC TCGTCGTGCT GGATGACATT
AGCCCAGGGA AGGAGAGCCT GGGGCCCGAC AGCTCCTCTG GGGGTCAAGA GGACCCCGCC
AGCCAGCAGT GGGCACGACC GCGCTTCACA CAGCCCTCCA AGATGAGGCG CCGGGTGATC
GCACGGCCCG TGGGTAGCTC CGTGCGGCTC AAGTGCGTGG CCAGCGGGCA CCCTCGGCCC
GACATCACGT GGATGAAGGA CGACCAGGCC TTGACGCGCC CAGAGGCCGC TGAGCCCAGG
AAGAAGAAGT GGACACTGAG CCTGAAGAAC CTGCGGCCGG AGGACAGCGG CAAATACACC
TGCCGCGTGT CGAACCGCGC GGGCGCCATC AACGCCACCT ACAAGGTGGA TGTGATCCAG
CGGACCCGTT CCAAGCCCGT GCTCACAGGC ACGCACCCCG TGAACACGAC GGTGGACTTC
GGGGGGACCA CGTCCTTCCA GTGCAAGGTG CGCAGCGACG TGAAGCCGGT GATCCAGTGG
CTGAAGCGCG TGGAGTACGG CGCCGAGGGC CGCCACAACT CCACCATCGA TGTGGGCGGC
CAGAAGTTTG TGGTGCTGCC CACGGGTGAC GTGTGGTCGC GGCCCGACGG CTCCTACCTC
AATAAGCTGC TCATCACCCG TGCCCGCCAG GACGATGCGG GCATGTACAT CTGCCTTGGC
GCCAACACCA TGGGCTACAG CTTCCGCAGC GCCTTCCTCA CCGTGCTGCC AGACCCAAAA
CCGCCAGGGC CACCTGTGGC CTCCTCGTCC TCGGCCACTA GCCTGCCGTG GCCCGTGGTC
ATCGGCATCC CAGCCGGCGC TGTCTTCATC CTGGGCACCC TGCTCCTGTG GCTTTGCCAG
GCCCAGAAGA AGCCGTGCAC CCCCGCGCCT GCCCCTCCCC TGCCTGGGCA CCGCCCGCCG
GGGACGGCCC GCGACCGCAG CGGAGACAAG GACCTTCCCT CGTTGGCCGC CCTCAGCGCT
GGCCCTGGTG TGGGGCTGTG TGAGGAGCAT GGGTCTCCGG CAGCCCCCCA GCACTTACTG
GGCCCAGGCC CAGTTGCTGG CCCTAAGTTG TACCCCAAAC TCTACACAGA CATCCACACA
CACACACACA CACACTCTCA CACACACTCA CACGTGGAGG GCAAGGTCCA CCAGCACATC
CACTATCAGT GCTAG

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OHu03560
Clone ID Related Accession (Same CDS sequence) NM_021923.3 , NM_001004358.1 , NM_001004356.2 , XM_011513486.1 , XM_011513487.1
Accession Version NM_001004356.2 Latest version! Documents for ORF clone product in dufault vector
Sequence Information ORF Nucleotide Sequence (Length: 1515bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags COA
ORF Insert Method CloneEZ® Seamless cloning technology
Insert Structure linear
Update Date 2017-04-27
Organism Homo sapiens(Human)
Product fibroblast growth factor receptor-like 1 precursor
Comment REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AY358303.1, BQ689625.1 and BC015228.1. On Apr 7, 2005 this sequence version replaced NM_001004356.1. Transcript Variant: This variant (1) represents the longest transcript. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AY358303.1, AF312678.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1968540, SAMEA2142348 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
1501
ATGACGCCGA GCCCCCTGTT GCTGCTCCTG CTGCCGCCGC TGCTGCTGGG GGCCTTCCCG 
CCGGCCGCCG CCGCCCGAGG CCCCCCAAAG ATGGCGGACA AGGTGGTCCC ACGGCAGGTG
GCCCGGCTGG GCCGCACTGT GCGGCTGCAG TGCCCAGTGG AGGGGGACCC GCCGCCGCTG
ACCATGTGGA CCAAGGATGG CCGCACCATC CACAGCGGCT GGAGCCGCTT CCGCGTGCTG
CCGCAGGGGC TGAAGGTGAA GCAGGTGGAG CGGGAGGATG CCGGCGTGTA CGTGTGCAAG
GCCACCAACG GCTTCGGCAG CCTGAGCGTC AACTACACCC TCGTCGTGCT GGATGACATT
AGCCCAGGGA AGGAGAGCCT GGGGCCCGAC AGCTCCTCTG GGGGTCAAGA GGACCCCGCC
AGCCAGCAGT GGGCACGACC GCGCTTCACA CAGCCCTCCA AGATGAGGCG CCGGGTGATC
GCACGGCCCG TGGGTAGCTC CGTGCGGCTC AAGTGCGTGG CCAGCGGGCA CCCTCGGCCC
GACATCACGT GGATGAAGGA CGACCAGGCC TTGACGCGCC CAGAGGCCGC TGAGCCCAGG
AAGAAGAAGT GGACACTGAG CCTGAAGAAC CTGCGGCCGG AGGACAGCGG CAAATACACC
TGCCGCGTGT CGAACCGCGC GGGCGCCATC AACGCCACCT ACAAGGTGGA TGTGATCCAG
CGGACCCGTT CCAAGCCCGT GCTCACAGGC ACGCACCCCG TGAACACGAC GGTGGACTTC
GGGGGGACCA CGTCCTTCCA GTGCAAGGTG CGCAGCGACG TGAAGCCGGT GATCCAGTGG
CTGAAGCGCG TGGAGTACGG CGCCGAGGGC CGCCACAACT CCACCATCGA TGTGGGCGGC
CAGAAGTTTG TGGTGCTGCC CACGGGTGAC GTGTGGTCGC GGCCCGACGG CTCCTACCTC
AATAAGCTGC TCATCACCCG TGCCCGCCAG GACGATGCGG GCATGTACAT CTGCCTTGGC
GCCAACACCA TGGGCTACAG CTTCCGCAGC GCCTTCCTCA CCGTGCTGCC AGACCCAAAA
CCGCCAGGGC CACCTGTGGC CTCCTCGTCC TCGGCCACTA GCCTGCCGTG GCCCGTGGTC
ATCGGCATCC CAGCCGGCGC TGTCTTCATC CTGGGCACCC TGCTCCTGTG GCTTTGCCAG
GCCCAGAAGA AGCCGTGCAC CCCCGCGCCT GCCCCTCCCC TGCCTGGGCA CCGCCCGCCG
GGGACGGCCC GCGACCGCAG CGGAGACAAG GACCTTCCCT CGTTGGCCGC CCTCAGCGCT
GGCCCTGGTG TGGGGCTGTG TGAGGAGCAT GGGTCTCCGG CAGCCCCCCA GCACTTACTG
GGCCCAGGCC CAGTTGCTGG CCCTAAGTTG TACCCCAAAC TCTACACAGA CATCCACACA
CACACACACA CACACTCTCA CACACACTCA CACGTGGAGG GCAAGGTCCA CCAGCACATC
CACTATCAGT GCTAG

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq NP_001004356.1
CDS150..1664
Misc Feature(1)66..68
Misc Feature(2)246..497
Misc Feature(3)279..467
Misc Feature(4)588..863
Misc Feature(5)618..863
Misc Feature(6)order(624..626,630..632,636..638)
Misc Feature(7)order(627..629,648..656,660..662)
Misc Feature(8)906..1214
Misc Feature(9)930..1217
Misc Feature(10)1284..1346
Exon (1)1..133
Exon (2)134..228
Exon (3)229..501
Exon (4)502..582
Exon (5)583..867
Exon (6)868..1221
Exon (7)1222..3215
Translation

Target ORF information:

RefSeq Version NM_001004356.2
Organism Homo sapiens(Human)
Definition Homo sapiens fibroblast growth factor receptor-like 1 (FGFRL1), transcript variant 1, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
NM_001004356.2

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
1501
ATGACGCCGA GCCCCCTGTT GCTGCTCCTG CTGCCGCCGC TGCTGCTGGG GGCCTTCCCG 
CCGGCCGCCG CCGCCCGAGG CCCCCCAAAG ATGGCGGACA AGGTGGTCCC ACGGCAGGTG
GCCCGGCTGG GCCGCACTGT GCGGCTGCAG TGCCCAGTGG AGGGGGACCC GCCGCCGCTG
ACCATGTGGA CCAAGGATGG CCGCACCATC CACAGCGGCT GGAGCCGCTT CCGCGTGCTG
CCGCAGGGGC TGAAGGTGAA GCAGGTGGAG CGGGAGGATG CCGGCGTGTA CGTGTGCAAG
GCCACCAACG GCTTCGGCAG CCTGAGCGTC AACTACACCC TCGTCGTGCT GGATGACATT
AGCCCAGGGA AGGAGAGCCT GGGGCCCGAC AGCTCCTCTG GGGGTCAAGA GGACCCCGCC
AGCCAGCAGT GGGCACGACC GCGCTTCACA CAGCCCTCCA AGATGAGGCG CCGGGTGATC
GCACGGCCCG TGGGTAGCTC CGTGCGGCTC AAGTGCGTGG CCAGCGGGCA CCCTCGGCCC
GACATCACGT GGATGAAGGA CGACCAGGCC TTGACGCGCC CAGAGGCCGC TGAGCCCAGG
AAGAAGAAGT GGACACTGAG CCTGAAGAAC CTGCGGCCGG AGGACAGCGG CAAATACACC
TGCCGCGTGT CGAACCGCGC GGGCGCCATC AACGCCACCT ACAAGGTGGA TGTGATCCAG
CGGACCCGTT CCAAGCCCGT GCTCACAGGC ACGCACCCCG TGAACACGAC GGTGGACTTC
GGGGGGACCA CGTCCTTCCA GTGCAAGGTG CGCAGCGACG TGAAGCCGGT GATCCAGTGG
CTGAAGCGCG TGGAGTACGG CGCCGAGGGC CGCCACAACT CCACCATCGA TGTGGGCGGC
CAGAAGTTTG TGGTGCTGCC CACGGGTGAC GTGTGGTCGC GGCCCGACGG CTCCTACCTC
AATAAGCTGC TCATCACCCG TGCCCGCCAG GACGATGCGG GCATGTACAT CTGCCTTGGC
GCCAACACCA TGGGCTACAG CTTCCGCAGC GCCTTCCTCA CCGTGCTGCC AGACCCAAAA
CCGCCAGGGC CACCTGTGGC CTCCTCGTCC TCGGCCACTA GCCTGCCGTG GCCCGTGGTC
ATCGGCATCC CAGCCGGCGC TGTCTTCATC CTGGGCACCC TGCTCCTGTG GCTTTGCCAG
GCCCAGAAGA AGCCGTGCAC CCCCGCGCCT GCCCCTCCCC TGCCTGGGCA CCGCCCGCCG
GGGACGGCCC GCGACCGCAG CGGAGACAAG GACCTTCCCT CGTTGGCCGC CCTCAGCGCT
GGCCCTGGTG TGGGGCTGTG TGAGGAGCAT GGGTCTCCGG CAGCCCCCCA GCACTTACTG
GGCCCAGGCC CAGTTGCTGG CCCTAAGTTG TACCCCAAAC TCTACACAGA CATCCACACA
CACACACACA CACACTCTCA CACACACTCA CACGTGGAGG GCAAGGTCCA CCAGCACATC
CACTATCAGT GCTAG

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OHu03560
Clone ID Related Accession (Same CDS sequence) NM_021923.3 , NM_001004358.1 , NM_001004356.2 , XM_011513486.1 , XM_011513487.1
Accession Version XM_011513486.1 Latest version! Documents for ORF clone product in dufault vector
Sequence Information ORF Nucleotide Sequence (Length: 1515bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags COA
ORF Insert Method CloneEZ® Seamless cloning technology
Insert Structure linear
Update Date 2016-06-06
Organism Homo sapiens(Human)
Product fibroblast growth factor receptor-like 1 isoform X1
Comment MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000004.12) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Homo sapiens Annotation Release 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
1501
ATGACGCCGA GCCCCCTGTT GCTGCTCCTG CTGCCGCCGC TGCTGCTGGG GGCCTTCCCG 
CCGGCCGCCG CCGCCCGAGG CCCCCCAAAG ATGGCGGACA AGGTGGTCCC ACGGCAGGTG
GCCCGGCTGG GCCGCACTGT GCGGCTGCAG TGCCCAGTGG AGGGGGACCC GCCGCCGCTG
ACCATGTGGA CCAAGGATGG CCGCACCATC CACAGCGGCT GGAGCCGCTT CCGCGTGCTG
CCGCAGGGGC TGAAGGTGAA GCAGGTGGAG CGGGAGGATG CCGGCGTGTA CGTGTGCAAG
GCCACCAACG GCTTCGGCAG CCTGAGCGTC AACTACACCC TCGTCGTGCT GGATGACATT
AGCCCAGGGA AGGAGAGCCT GGGGCCCGAC AGCTCCTCTG GGGGTCAAGA GGACCCCGCC
AGCCAGCAGT GGGCACGACC GCGCTTCACA CAGCCCTCCA AGATGAGGCG CCGGGTGATC
GCACGGCCCG TGGGTAGCTC CGTGCGGCTC AAGTGCGTGG CCAGCGGGCA CCCTCGGCCC
GACATCACGT GGATGAAGGA CGACCAGGCC TTGACGCGCC CAGAGGCCGC TGAGCCCAGG
AAGAAGAAGT GGACACTGAG CCTGAAGAAC CTGCGGCCGG AGGACAGCGG CAAATACACC
TGCCGCGTGT CGAACCGCGC GGGCGCCATC AACGCCACCT ACAAGGTGGA TGTGATCCAG
CGGACCCGTT CCAAGCCCGT GCTCACAGGC ACGCACCCCG TGAACACGAC GGTGGACTTC
GGGGGGACCA CGTCCTTCCA GTGCAAGGTG CGCAGCGACG TGAAGCCGGT GATCCAGTGG
CTGAAGCGCG TGGAGTACGG CGCCGAGGGC CGCCACAACT CCACCATCGA TGTGGGCGGC
CAGAAGTTTG TGGTGCTGCC CACGGGTGAC GTGTGGTCGC GGCCCGACGG CTCCTACCTC
AATAAGCTGC TCATCACCCG TGCCCGCCAG GACGATGCGG GCATGTACAT CTGCCTTGGC
GCCAACACCA TGGGCTACAG CTTCCGCAGC GCCTTCCTCA CCGTGCTGCC AGACCCAAAA
CCGCCAGGGC CACCTGTGGC CTCCTCGTCC TCGGCCACTA GCCTGCCGTG GCCCGTGGTC
ATCGGCATCC CAGCCGGCGC TGTCTTCATC CTGGGCACCC TGCTCCTGTG GCTTTGCCAG
GCCCAGAAGA AGCCGTGCAC CCCCGCGCCT GCCCCTCCCC TGCCTGGGCA CCGCCCGCCG
GGGACGGCCC GCGACCGCAG CGGAGACAAG GACCTTCCCT CGTTGGCCGC CCTCAGCGCT
GGCCCTGGTG TGGGGCTGTG TGAGGAGCAT GGGTCTCCGG CAGCCCCCCA GCACTTACTG
GGCCCAGGCC CAGTTGCTGG CCCTAAGTTG TACCCCAAAC TCTACACAGA CATCCACACA
CACACACACA CACACTCTCA CACACACTCA CACGTGGAGG GCAAGGTCCA CCAGCACATC
CACTATCAGT GCTAG

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq XP_011511788.1
CDS154..1668
Misc Feature(1)250..501
Misc Feature(2)283..471
Misc Feature(3)592..867
Misc Feature(4)622..867
Misc Feature(5)order(628..630,634..636,640..642)
Misc Feature(6)order(631..633,652..660,664..666)
Misc Feature(7)910..1218
Misc Feature(8)934..1221
Translation

Target ORF information:

RefSeq Version XM_011513486.1
Organism Homo sapiens(Human)
Definition Homo sapiens fibroblast growth factor receptor-like 1 (FGFRL1), transcript variant X1, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
XM_011513486.1

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
1501
ATGACGCCGA GCCCCCTGTT GCTGCTCCTG CTGCCGCCGC TGCTGCTGGG GGCCTTCCCG 
CCGGCCGCCG CCGCCCGAGG CCCCCCAAAG ATGGCGGACA AGGTGGTCCC ACGGCAGGTG
GCCCGGCTGG GCCGCACTGT GCGGCTGCAG TGCCCAGTGG AGGGGGACCC GCCGCCGCTG
ACCATGTGGA CCAAGGATGG CCGCACCATC CACAGCGGCT GGAGCCGCTT CCGCGTGCTG
CCGCAGGGGC TGAAGGTGAA GCAGGTGGAG CGGGAGGATG CCGGCGTGTA CGTGTGCAAG
GCCACCAACG GCTTCGGCAG CCTGAGCGTC AACTACACCC TCGTCGTGCT GGATGACATT
AGCCCAGGGA AGGAGAGCCT GGGGCCCGAC AGCTCCTCTG GGGGTCAAGA GGACCCCGCC
AGCCAGCAGT GGGCACGACC GCGCTTCACA CAGCCCTCCA AGATGAGGCG CCGGGTGATC
GCACGGCCCG TGGGTAGCTC CGTGCGGCTC AAGTGCGTGG CCAGCGGGCA CCCTCGGCCC
GACATCACGT GGATGAAGGA CGACCAGGCC TTGACGCGCC CAGAGGCCGC TGAGCCCAGG
AAGAAGAAGT GGACACTGAG CCTGAAGAAC CTGCGGCCGG AGGACAGCGG CAAATACACC
TGCCGCGTGT CGAACCGCGC GGGCGCCATC AACGCCACCT ACAAGGTGGA TGTGATCCAG
CGGACCCGTT CCAAGCCCGT GCTCACAGGC ACGCACCCCG TGAACACGAC GGTGGACTTC
GGGGGGACCA CGTCCTTCCA GTGCAAGGTG CGCAGCGACG TGAAGCCGGT GATCCAGTGG
CTGAAGCGCG TGGAGTACGG CGCCGAGGGC CGCCACAACT CCACCATCGA TGTGGGCGGC
CAGAAGTTTG TGGTGCTGCC CACGGGTGAC GTGTGGTCGC GGCCCGACGG CTCCTACCTC
AATAAGCTGC TCATCACCCG TGCCCGCCAG GACGATGCGG GCATGTACAT CTGCCTTGGC
GCCAACACCA TGGGCTACAG CTTCCGCAGC GCCTTCCTCA CCGTGCTGCC AGACCCAAAA
CCGCCAGGGC CACCTGTGGC CTCCTCGTCC TCGGCCACTA GCCTGCCGTG GCCCGTGGTC
ATCGGCATCC CAGCCGGCGC TGTCTTCATC CTGGGCACCC TGCTCCTGTG GCTTTGCCAG
GCCCAGAAGA AGCCGTGCAC CCCCGCGCCT GCCCCTCCCC TGCCTGGGCA CCGCCCGCCG
GGGACGGCCC GCGACCGCAG CGGAGACAAG GACCTTCCCT CGTTGGCCGC CCTCAGCGCT
GGCCCTGGTG TGGGGCTGTG TGAGGAGCAT GGGTCTCCGG CAGCCCCCCA GCACTTACTG
GGCCCAGGCC CAGTTGCTGG CCCTAAGTTG TACCCCAAAC TCTACACAGA CATCCACACA
CACACACACA CACACTCTCA CACACACTCA CACGTGGAGG GCAAGGTCCA CCAGCACATC
CACTATCAGT GCTAG

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OHu03560
Clone ID Related Accession (Same CDS sequence) NM_021923.3 , NM_001004358.1 , NM_001004356.2 , XM_011513486.1 , XM_011513487.1
Accession Version XM_011513487.1 Latest version! Documents for ORF clone product in dufault vector
Sequence Information ORF Nucleotide Sequence (Length: 1515bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags COA
ORF Insert Method CloneEZ® Seamless cloning technology
Insert Structure linear
Update Date 2015-03-12
Organism Homo sapiens(Human)
Product fibroblast growth factor receptor-like 1 isoform X1
Comment

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
1501
ATGACGCCGA GCCCCCTGTT GCTGCTCCTG CTGCCGCCGC TGCTGCTGGG GGCCTTCCCG 
CCGGCCGCCG CCGCCCGAGG CCCCCCAAAG ATGGCGGACA AGGTGGTCCC ACGGCAGGTG
GCCCGGCTGG GCCGCACTGT GCGGCTGCAG TGCCCAGTGG AGGGGGACCC GCCGCCGCTG
ACCATGTGGA CCAAGGATGG CCGCACCATC CACAGCGGCT GGAGCCGCTT CCGCGTGCTG
CCGCAGGGGC TGAAGGTGAA GCAGGTGGAG CGGGAGGATG CCGGCGTGTA CGTGTGCAAG
GCCACCAACG GCTTCGGCAG CCTGAGCGTC AACTACACCC TCGTCGTGCT GGATGACATT
AGCCCAGGGA AGGAGAGCCT GGGGCCCGAC AGCTCCTCTG GGGGTCAAGA GGACCCCGCC
AGCCAGCAGT GGGCACGACC GCGCTTCACA CAGCCCTCCA AGATGAGGCG CCGGGTGATC
GCACGGCCCG TGGGTAGCTC CGTGCGGCTC AAGTGCGTGG CCAGCGGGCA CCCTCGGCCC
GACATCACGT GGATGAAGGA CGACCAGGCC TTGACGCGCC CAGAGGCCGC TGAGCCCAGG
AAGAAGAAGT GGACACTGAG CCTGAAGAAC CTGCGGCCGG AGGACAGCGG CAAATACACC
TGCCGCGTGT CGAACCGCGC GGGCGCCATC AACGCCACCT ACAAGGTGGA TGTGATCCAG
CGGACCCGTT CCAAGCCCGT GCTCACAGGC ACGCACCCCG TGAACACGAC GGTGGACTTC
GGGGGGACCA CGTCCTTCCA GTGCAAGGTG CGCAGCGACG TGAAGCCGGT GATCCAGTGG
CTGAAGCGCG TGGAGTACGG CGCCGAGGGC CGCCACAACT CCACCATCGA TGTGGGCGGC
CAGAAGTTTG TGGTGCTGCC CACGGGTGAC GTGTGGTCGC GGCCCGACGG CTCCTACCTC
AATAAGCTGC TCATCACCCG TGCCCGCCAG GACGATGCGG GCATGTACAT CTGCCTTGGC
GCCAACACCA TGGGCTACAG CTTCCGCAGC GCCTTCCTCA CCGTGCTGCC AGACCCAAAA
CCGCCAGGGC CACCTGTGGC CTCCTCGTCC TCGGCCACTA GCCTGCCGTG GCCCGTGGTC
ATCGGCATCC CAGCCGGCGC TGTCTTCATC CTGGGCACCC TGCTCCTGTG GCTTTGCCAG
GCCCAGAAGA AGCCGTGCAC CCCCGCGCCT GCCCCTCCCC TGCCTGGGCA CCGCCCGCCG
GGGACGGCCC GCGACCGCAG CGGAGACAAG GACCTTCCCT CGTTGGCCGC CCTCAGCGCT
GGCCCTGGTG TGGGGCTGTG TGAGGAGCAT GGGTCTCCGG CAGCCCCCCA GCACTTACTG
GGCCCAGGCC CAGTTGCTGG CCCTAAGTTG TACCCCAAAC TCTACACAGA CATCCACACA
CACACACACA CACACTCTCA CACACACTCA CACGTGGAGG GCAAGGTCCA CCAGCACATC
CACTATCAGT GCTAG

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq XP_011511789.1
Translation

Target ORF information:

RefSeq Version XM_011513487.1
Organism Homo sapiens(Human)
Definition Homo sapiens fibroblast growth factor receptor-like 1 (FGFRL1), transcript variant X2, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
XM_011513487.1

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
1501
ATGACGCCGA GCCCCCTGTT GCTGCTCCTG CTGCCGCCGC TGCTGCTGGG GGCCTTCCCG 
CCGGCCGCCG CCGCCCGAGG CCCCCCAAAG ATGGCGGACA AGGTGGTCCC ACGGCAGGTG
GCCCGGCTGG GCCGCACTGT GCGGCTGCAG TGCCCAGTGG AGGGGGACCC GCCGCCGCTG
ACCATGTGGA CCAAGGATGG CCGCACCATC CACAGCGGCT GGAGCCGCTT CCGCGTGCTG
CCGCAGGGGC TGAAGGTGAA GCAGGTGGAG CGGGAGGATG CCGGCGTGTA CGTGTGCAAG
GCCACCAACG GCTTCGGCAG CCTGAGCGTC AACTACACCC TCGTCGTGCT GGATGACATT
AGCCCAGGGA AGGAGAGCCT GGGGCCCGAC AGCTCCTCTG GGGGTCAAGA GGACCCCGCC
AGCCAGCAGT GGGCACGACC GCGCTTCACA CAGCCCTCCA AGATGAGGCG CCGGGTGATC
GCACGGCCCG TGGGTAGCTC CGTGCGGCTC AAGTGCGTGG CCAGCGGGCA CCCTCGGCCC
GACATCACGT GGATGAAGGA CGACCAGGCC TTGACGCGCC CAGAGGCCGC TGAGCCCAGG
AAGAAGAAGT GGACACTGAG CCTGAAGAAC CTGCGGCCGG AGGACAGCGG CAAATACACC
TGCCGCGTGT CGAACCGCGC GGGCGCCATC AACGCCACCT ACAAGGTGGA TGTGATCCAG
CGGACCCGTT CCAAGCCCGT GCTCACAGGC ACGCACCCCG TGAACACGAC GGTGGACTTC
GGGGGGACCA CGTCCTTCCA GTGCAAGGTG CGCAGCGACG TGAAGCCGGT GATCCAGTGG
CTGAAGCGCG TGGAGTACGG CGCCGAGGGC CGCCACAACT CCACCATCGA TGTGGGCGGC
CAGAAGTTTG TGGTGCTGCC CACGGGTGAC GTGTGGTCGC GGCCCGACGG CTCCTACCTC
AATAAGCTGC TCATCACCCG TGCCCGCCAG GACGATGCGG GCATGTACAT CTGCCTTGGC
GCCAACACCA TGGGCTACAG CTTCCGCAGC GCCTTCCTCA CCGTGCTGCC AGACCCAAAA
CCGCCAGGGC CACCTGTGGC CTCCTCGTCC TCGGCCACTA GCCTGCCGTG GCCCGTGGTC
ATCGGCATCC CAGCCGGCGC TGTCTTCATC CTGGGCACCC TGCTCCTGTG GCTTTGCCAG
GCCCAGAAGA AGCCGTGCAC CCCCGCGCCT GCCCCTCCCC TGCCTGGGCA CCGCCCGCCG
GGGACGGCCC GCGACCGCAG CGGAGACAAG GACCTTCCCT CGTTGGCCGC CCTCAGCGCT
GGCCCTGGTG TGGGGCTGTG TGAGGAGCAT GGGTCTCCGG CAGCCCCCCA GCACTTACTG
GGCCCAGGCC CAGTTGCTGG CCCTAAGTTG TACCCCAAAC TCTACACAGA CATCCACACA
CACACACACA CACACTCTCA CACACACTCA CACGTGGAGG GCAAGGTCCA CCAGCACATC
CACTATCAGT GCTAG

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

book

MicroRNA-210 promotes cancer angiogenesis by targeting fibroblast growth factor receptor-like 1 in hepatocellular carcinoma.
Oncology reports36(5)2553-2562(2016 Nov)
Yang Y,Zhang J,Xia T,Li G,Tian T,Wang M,Wang R,Zhao L,Yang Y,Lan K,Zhou W


book

Receptor FGFRL1 does not promote cell proliferation but induces cell adhesion.
International journal of molecular medicine38(1)30-8(2016 Jul)
Yang X,Steinberg F,Zhuang L,Bessey R,Trueb B


book

Cell-cell fusion induced by the Ig3 domain of receptor FGFRL1 in CHO cells.
Biochimica et biophysica acta1853(10 Pt A)2273-85(2015 Oct)
Zhuang L,Pandey AV,Villiger PM,Trueb B


book

Identification of a novel FGFRL1 MicroRNA target site polymorphism for bone mineral density in meta-analyses of genome-wide association studies.
Human molecular genetics24(16)4710-27(2015 Aug)
Niu T,Liu N,Zhao M,Xie G,Zhang L,Li J,Pei YF,Shen H,Fu X,He H,Lu S,Chen XD,Tan LJ,Yang TL,Guo Y,Leo PJ,Duncan EL,Shen J,Guo YF,Nicholson GC,Prince RL,Eisman JA,Jones G,Sambrook PN,Hu X,Das PM,Tian Q,Zhu XZ,Papasian CJ,Brown MA,Uitterlinden AG,Wang YP,Xiang S,Deng HW


book

Multistage genome-wide association meta-analyses identified two new loci for bone mineral density.
Human molecular genetics23(7)1923-33(2014 Apr)
Zhang L,Choi HJ,Estrada K,Leo PJ,Li J,Pei YF,Zhang Y,Lin Y,Shen H,Liu YZ,Liu Y,Zhao Y,Zhang JG,Tian Q,Wang YP,Han Y,Ran S,Hai R,Zhu XZ,Wu S,Yan H,Liu X,Yang TL,Guo Y,Zhang F,Guo YF,Chen Y,Chen X,Tan L,Zhang L,Deng FY,Deng H,Rivadeneira F,Duncan EL,Lee JY,Han BG,Cho NH,Nicholson GC,McCloskey E,Eastell R,Prince RL,Eisman JA,Jones G,Reid IR,Sambrook PN,Dennison EM,Danoy P,Yerges-Armstrong LM,Streeten EA,Hu T,Xiang S,Papasian CJ,Brown MA,Shin CS,Uitterlinden AG,Deng HW


 
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