Gene Symbol | NEURL1B |
Entrez Gene ID | 54492 |
Full Name | neuralized E3 ubiquitin protein ligase 1B |
Synonyms | NEURL3,RNF67B,hNeur2,neur2 |
General protein information |
|
Gene Type | protein-coding |
Organism | Homo sapiens(human) |
Genome | |
Disorder MIM: |
ORF » Species Summary » Homo sapiens » NEURL1B cDNA ORF clone
gRNAs
Gene Symbol | NEURL1B |
Entrez Gene ID | 54492 |
Full Name | neuralized E3 ubiquitin protein ligase 1B |
Synonyms | NEURL3,RNF67B,hNeur2,neur2 |
General protein information |
|
Gene Type | protein-coding |
Organism | Homo sapiens(human) |
Genome | |
Disorder MIM: |
mRNA | Protein | Name |
---|---|---|
NM_001308177.1 | NP_001295106.1 | E3 ubiquitin-protein ligase NEURL1B isoform hNEUR2-deltaNHR1 |
NM_001308178.2 | NP_001295107.1 | E3 ubiquitin-protein ligase NEURL1B isoform hNEUR2-deltaNHR2 |
NM_001142651.2 | NP_001136123.1 | E3 ubiquitin-protein ligase NEURL1B isoform hNEUR2 |
NM_001308178.1 | NP_001295107.1 | E3 ubiquitin-protein ligase NEURL1B isoform hNEUR2-deltaNHR2 |
NM_001308177.2 | NP_001295106.1 | E3 ubiquitin-protein ligase NEURL1B isoform hNEUR2-deltaNHR1 |
NM_001142651.3 | NP_001136123.1 | E3 ubiquitin-protein ligase NEURL1B isoform hNEUR2 |
Pan troglodytes (chimpanzee) | NEURL1B | XP_003311007.1 |
Mus musculus (house mouse) | Neurl1b | NP_001075125.1 |
Rattus norvegicus (Norway rat) | Neurl1b | NP_001136124.1 |
Anopheles gambiae (African malaria mosquito) | AgaP_AGAP001999 | XP_003435991.1 |
Bos taurus (cattle) | NEURL1B | XP_002696317.2 |
Homo sapiens (human) | NEURL1B | NP_001136123.1 |
NEURL1B | XP_002804683.1 | |
Canis lupus familiaris (dog) | NEURL1B | XP_005619504.1 |
Gallus gallus (chicken) | NEURL1B | XP_425198.2 |
Drosophila melanogaster (fruit fly) | neur | NP_731311.1 |
Caenorhabditis elegans (roundworm) | F10D7.5 | NP_510818.3 |
Xenopus tropicalis (tropical clawed frog) | neurl1b | XP_002941593.1 |
Genome-wide association studies and heritability estimates of body mass index related phenotypes in Bangladeshi adults.
Scannell Bryan M, Argos M, Pierce B, Tong L, Rakibuz-Zaman M, Ahmed A, Rahman M, Islam T, Yunus M, Parvez F, Roy S, Jasmine F, Baron JA, Kibriya MG, Ahsan H
PloS one9(8)e105062(2014)
Neuralized-2: expression in human and rodents and interaction with Delta-like ligands.
Rullinkov G, Tamme R, Sarapuu A, Laur?n J, Sepp M, Palm K, Timmusk T
Biochemical and biophysical research communications389(3)420-5(2009 Nov)
Neuralized-2 regulates a Notch ligand in cooperation with Mind bomb-1.
Song R, Koo BK, Yoon KJ, Yoon MJ, Yoo KW, Kim HT, Oh HJ, Kim YY, Han JK, Kim CH, Kong YY
The Journal of biological chemistry281(47)36391-400(2006 Nov)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
Neur2, in contrast to Neur1, is highly expressed during embryonic development of the brain and several non-neural tissues and its mRNA levels subside postnatally.
Title: Neuralized-2: expression in human and rodents and interaction with Delta-like ligands.
The following NEURL1B gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the NEURL1B cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
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CloneID | OHu12852 | |
Clone ID Related Accession (Same CDS sequence) | NM_001142651.2 , NM_001142651.3 | |
Accession Version | NM_001142651.2 | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1668bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | ![]() |
Clone information | Clone Map | ![]() |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-02-24 | |
Organism | Homo sapiens(human) | |
Product | E3 ubiquitin-protein ligase NEURL1B isoform hNEUR2 | |
Comment | Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from GQ414757.1, CN267889.1, HY104395.1, AK096661.1 and AK026748.1. On Apr 28, 2015 this sequence version replaced NM_001142651.1. Transcript Variant: This variant (1) represents the longest transcript and encodes the longest isoform (hNEUR2). ##Evidence-Data-START## Transcript exon combination :: GQ414757.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1968540, SAMEA2142348 [ECO:0000348] ##Evidence-Data-END## |
1 | ATGGGCAACA CGGTGCACCG GACCCTGCCA GACCCGAGCC CACCGGCGCG CCTCCTGGCC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_001136123.1 |
CDS | 142..1809 |
Translation |
Target ORF information:
Target ORF information:
|
![]() |
1 | ATGGGCAACA CGGTGCACCG GACCCTGCCA GACCCGAGCC CACCGGCGCG CCTCCTGGCC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OHu12852 | |
Clone ID Related Accession (Same CDS sequence) | NM_001142651.2 , NM_001142651.3 | |
Accession Version | NM_001142651.3 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1668bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | ![]() |
Clone information | Clone Map | ![]() |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-10-24 | |
Organism | Homo sapiens(human) | |
Product | E3 ubiquitin-protein ligase NEURL1B isoform hNEUR2 | |
Comment | Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AC027309.3, GQ414757.1, CN267889.1, HY104395.1, AK096661.1 and AK026748.1. On May 17, 2019 this sequence version replaced NM_001142651.2. Transcript Variant: This variant (1) represents the longest transcript and encodes the longest isoform (hNEUR2). ##Evidence-Data-START## Transcript exon combination :: GQ414757.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1968540, SAMEA2142348 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000369800.6/ ENSP00000358815.5 RefSeq Select criteria :: based on conservation, expression, longest protein ##RefSeq-Attributes-END## |
1 | ATGGGCAACA CGGTGCACCG GACCCTGCCA GACCCGAGCC CACCGGCGCG CCTCCTGGCC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_001136123.1 |
CDS | 145..1812 |
Translation |
Target ORF information:
Target ORF information:
|
![]() |
1 | ATGGGCAACA CGGTGCACCG GACCCTGCCA GACCCGAGCC CACCGGCGCG CCTCCTGGCC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OHu68366 | |
Clone ID Related Accession (Same CDS sequence) | NM_001308177.1 , NM_001308177.2 | |
Accession Version | NM_001308177.1 | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1122bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | ![]() |
Clone information | Clone Map | ![]() |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2018-06-30 | |
Organism | Homo sapiens(human) | |
Product | E3 ubiquitin-protein ligase NEURL1B isoform hNEUR2-deltaNHR1 | |
Comment | Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from GQ414758.1, CN267889.1, HY104395.1, AK096661.1 and AK026748.1. Transcript Variant: This variant (2) lacks an alternate in-frame exon in the 5' coding region, compared to variant 1, resulting in an isoform (hNEUR2-deltaNHR1) that is shorter than isoform hNEUR2. ##Evidence-Data-START## Transcript exon combination :: GQ414758.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2142348, SAMEA2152568 [ECO:0000348] ##Evidence-Data-END## |
1 | ATGGGCAACA CGGTGCACCG GACCCTGCCA GAGAGCGCCT TCGCTGACAC GCTGACGCCC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_001295106.1 |
CDS | 142..1263 |
Translation |
Target ORF information:
Target ORF information:
|
![]() |
1 | ATGGGCAACA CGGTGCACCG GACCCTGCCA GAGAGCGCCT TCGCTGACAC GCTGACGCCC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OHu68366 | |
Clone ID Related Accession (Same CDS sequence) | NM_001308177.1 , NM_001308177.2 | |
Accession Version | NM_001308177.2 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1122bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | ![]() |
Clone information | Clone Map | ![]() |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-05-30 | |
Organism | Homo sapiens(human) | |
Product | E3 ubiquitin-protein ligase NEURL1B isoform hNEUR2-deltaNHR1 | |
Comment | Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AC027309.3, GQ414758.1, CN267889.1, HY104395.1, AK096661.1 and AK026748.1. On May 31, 2019 this sequence version replaced NM_001308177.1. Transcript Variant: This variant (2) lacks an alternate in-frame exon in the 5' coding region, compared to variant 1, resulting in an isoform (hNEUR2-deltaNHR1) that is shorter than isoform hNEUR2. ##Evidence-Data-START## Transcript exon combination :: GQ414758.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2142348, SAMEA2152568 [ECO:0000348] ##Evidence-Data-END## |
1 | ATGGGCAACA CGGTGCACCG GACCCTGCCA GAGAGCGCCT TCGCTGACAC GCTGACGCCC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_001295106.1 |
CDS | 145..1266 |
Translation |
Target ORF information:
Target ORF information:
|
![]() |
1 | ATGGGCAACA CGGTGCACCG GACCCTGCCA GAGAGCGCCT TCGCTGACAC GCTGACGCCC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OHu68367 | |
Clone ID Related Accession (Same CDS sequence) | NM_001308178.2 , NM_001308178.1 | |
Accession Version | NM_001308178.2 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 948bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | ![]() |
Clone information | Clone Map | ![]() |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-05-30 | |
Organism | Homo sapiens(human) | |
Product | E3 ubiquitin-protein ligase NEURL1B isoform hNEUR2-deltaNHR2 | |
Comment | Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AC027309.3, GQ414759.1, CN267889.1, HY104395.1, AK096661.1 and AK026748.1. On May 31, 2019 this sequence version replaced NM_001308178.1. Transcript Variant: This variant (3) lacks an alternate in-frame exon in the central coding region, compared to variant 1, resulting in an isoform (hNEUR2-deltaNHR2) that is shorter than isoform hNEUR2. ##Evidence-Data-START## Transcript exon combination :: GQ414759.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1968540, SAMN02400288 [ECO:0000348] ##Evidence-Data-END## |
1 | ATGGGCAACA CGGTGCACCG GACCCTGCCA GACCCGAGCC CACCGGCGCG CCTCCTGGCC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_001295107.1 |
CDS | 145..1092 |
Translation |
Target ORF information:
Target ORF information:
|
![]() |
1 | ATGGGCAACA CGGTGCACCG GACCCTGCCA GACCCGAGCC CACCGGCGCG CCTCCTGGCC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OHu68367 | |
Clone ID Related Accession (Same CDS sequence) | NM_001308178.2 , NM_001308178.1 | |
Accession Version | NM_001308178.1 | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 948bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | ![]() |
Clone information | Clone Map | ![]() |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2018-06-30 | |
Organism | Homo sapiens(human) | |
Product | E3 ubiquitin-protein ligase NEURL1B isoform hNEUR2-deltaNHR2 | |
Comment | Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from GQ414759.1, CN267889.1, HY104395.1, AK096661.1 and AK026748.1. On Apr 28, 2015 this sequence version replaced XM_011534571.1. Transcript Variant: This variant (3) lacks an alternate in-frame exon in the central coding region, compared to variant 1, resulting in an isoform (hNEUR2-deltaNHR2) that is shorter than isoform hNEUR2. ##Evidence-Data-START## Transcript exon combination :: GQ414759.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1968540, SAMN02400288 [ECO:0000348] ##Evidence-Data-END## |
1 | ATGGGCAACA CGGTGCACCG GACCCTGCCA GACCCGAGCC CACCGGCGCG CCTCCTGGCC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_001295107.1 |
CDS | 142..1089 |
Translation |
Target ORF information:
Target ORF information:
|
![]() |
1 | ATGGGCAACA CGGTGCACCG GACCCTGCCA GACCCGAGCC CACCGGCGCG CCTCCTGGCC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
Genome-wide association studies and heritability estimates of body mass index related phenotypes in Bangladeshi adults. |
Neuralized-2: expression in human and rodents and interaction with Delta-like ligands. |
Neuralized-2 regulates a Notch ligand in cooperation with Mind bomb-1. |