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TRIM44 cDNA ORF clone, Homo sapiens(Human)

Gene Symbol TRIM44
Entrez Gene ID 54765
Full Name tripartite motif containing 44
Synonyms AN3,DIPB,HSA249128,MC7
General protein information
Preferred Names

tripartite motif containing 44

Names

tripartite motif-containing protein 44

Gene Type protein-coding
Organism Homo sapiens(Human)
Genome

11

11p13

Summary This gene encodes a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, namely a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. [provided by RefSeq, Jul 2008].
Disorder MIM:

612298


mRNA and Protein(s)

mRNA Protein Name
XM_006718254.1 XP_006718317.1 tripartite motif-containing protein 44 isoform X1
NM_017583.5 NP_060053.2 tripartite motif-containing protein 44



Bos taurus (cattle) TRIM44 NP_001098484.1
Xenopus tropicalis (tropical clawed frog) trim44 XP_002937339.1
Mus musculus (house mouse) Trim44 NP_064663.2
Danio rerio (zebrafish) trim44 NP_001155221.2
Macaca mulatta (rhesus monkey) TRIM44 XP_001114934.1
Homo sapiens (human) TRIM44 NP_060053.2
Rattus norvegicus (Norway rat) Trim44 NP_001013221.1
Pan troglodytes (chimpanzee) TRIM44 XP_508888.2
Canis lupus familiaris (dog) TRIM44 XP_540542.3


Related articles in PubMed

A novel prognostic factor TRIM44 promotes cell proliferation and migration, and inhibits apoptosis in testicular germ cell tumor.
Yamada Y, Takayama KI, Fujimura T, Ashikari D, Obinata D, Takahashi S, Ikeda K, Kakutani S, Urano T, Fukuhara H, Homma Y, Inoue S
Cancer science108(1)32-41(2017 Jan)

High expression of TRIM44 is associated with enhanced cell proliferation, migration, invasion, and resistance to doxorubicin in hepatocellular carcinoma.
Zhu X, Wu Y, Miao X, Li C, Yin H, Yang S, Lu X, Liu Y, Chen Y, Shen R, Chen X, He S
Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine37(11)14615-14628(2016 Nov)

Variants in TRIM44 Cause Aniridia by Impairing PAX6 Expression.
Zhang X, Qin G, Chen G, Li T, Gao L, Huang L, Zhang Y, Ouyang K, Wang Y, Pang Y, Zeng B, Yu L
Human mutation36(12)1164-7(2015 Dec)

Trim44 facilitates the migration and invasion of human lung cancer cells via the NF-κB signaling pathway.
Luo Q, Lin H, Ye X, Huang J, Lu S, Xu L
International journal of clinical oncology20(3)508-17(2015 Jun)

Novel function of Trim44 promotes an antiviral response by stabilizing VISA.
Yang B, Wang J, Wang Y, Zhou H, Wu X, Tian Z, Sun B
Journal of immunology (Baltimore, Md. : 1950)190(7)3613-9(2013 Apr)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

These results suggest that tripartite motif-containing protein 44 protein could play a crucial role in tumor invasion through its overexpression and highlight its usefulness as a predictor and potential therapeutic target in esophageal squamous cell carcinoma
Title: Overexpression of TRIM44 is related to invasive potential and malignant outcomes in esophageal squamous cell carcinoma.

results suggest that high expression of TRIM44 is associated with poor prognosis and that TRIM44 plays significant role in cell proliferation, migration, and anti-apoptosis in testicular germ cell tumor
Title: A novel prognostic factor TRIM44 promotes cell proliferation and migration, and inhibits apoptosis in testicular germ cell tumor.

High expression of TRIM44 is associated with enhanced cell proliferation, migration, invasion, and resistance to doxorubicin in hepatocellular carcinoma.
Title: High expression of TRIM44 is associated with enhanced cell proliferation, migration, invasion, and resistance to doxorubicin in hepatocellular carcinoma.

Variants in TRIM44 Cause Aniridia by Impairing PAX6 Expression
Title: Variants in TRIM44 Cause Aniridia by Impairing PAX6 Expression.

Trim44 promotes non-small cell lung cancer development through activation of NF-kappaB signaling via upregulating CXCL16 and MMP9 expression.
Title: Trim44 facilitates the migration and invasion of human lung cancer cells via the NF-κB signaling pathway.

The following TRIM44 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the TRIM44 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

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***CloneID RefSeq Accession Definition **Vector *Turnaround time Price (USD) Select
OHu02464 NM_017583.5
Latest version!
Homo sapiens tripartite motif containing 44 (TRIM44), mRNA. pcDNA3.1+/C-(K)DYK or customized vector
in pcDNA3.1+/C-(K)DYK
$159.50-$223.30
$319.00
OHu44905 XM_006718254.1
Latest version!
Homo sapiens tripartite motif containing 44 (TRIM44), transcript variant X1, mRNA. pcDNA3.1+/C-(K)DYK or customized vector 7-9 $139.30
$199.00

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2-4 Clone 40% OFF
5 or more Clone 50% OFF
All Other ORF Clones
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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.


CloneID OHu02464
Clone ID Related Accession (Same CDS sequence) NM_017583.5
Accession Version NM_017583.5 Latest version! Documents for ORF clone product in dufault vector
Sequence Information ORF Nucleotide Sequence (Length: 1035bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags COA
ORF Insert Method CloneEZ® Seamless cloning technology
Insert Structure linear
Update Date 2017-04-23
Organism Homo sapiens(Human)
Product tripartite motif-containing protein 44
Comment REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from BI550863.1, AK074242.1, DA128342.1, DA158251.1, DA131915.1, CX788887.1, CX871447.1, BI222592.1, CA445350.1 and BQ014398.1. This sequence is a reference standard in the RefSeqGene project. On Nov 25, 2014 this sequence version replaced NM_017583.4. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC024031.2, AK074242.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
ATGGCCTCTG GAGTGGGCGC GGCCTTCGAG GAACTGCCTC ACGACGGCAC GTGTGACGAG 
TGCGAGCCCG ACGAGGCTCC GGGGGCCGAG GAAGTGTGCC GAGAATGCGG CTTCTGCTAC
TGCCGCCGCC ATGCCGAGGC GCACAGGCAG AAGTTCCTCA GTCACCATCT GGCCGAATAC
GTCCACGGCT CCCAGGCCTG GACCCCGCCA GCTGACGGAG AGGGGGCGGG GAAGGAAGAA
GCGGAGGTCA AGGTGGAGCA GGAGAGGGAG ATAGAAAGCG AGGCAGGGGA AGAGAGTGAG
TCGGAGGAAG AGAGCGAGTC AGAGGAAGAG AGCGAGACAG AGGAAGAGAG TGAGGATGAG
AGCGATGAGG AGAGTGAAGA AGACAGCGAG GAAGAAATGG AGGATGAGCA AGAAAGCGAG
GCCGAAGAAG ACAACCAAGA AGAAGGGGAA TCCGAGGCGG AGGGAGAAAC TGAGGCAGAA
AGTGAATTTG ACCCAGAAAT AGAAATGGAA GCAGAGAGAG TGGCCAAGAG GAAGTGTCCG
GACCATGGGC TTGATTTGAG TACCTATTGC CAGGAAGATA GGCAGCTCAT CTGTGTCCTG
TGTCCAGTCA TTGGGGCTCA CCAGGGCCAC CAACTCTCCA CCCTAGACGA AGCCTTTGAA
GAATTAAGAA GCAAAGACTC AGGTGGACTG AAGGCCGCTA TGATCGAATT GGTGGAAAGG
TTGAAGTTCA AGAGCTCAGA CCCTAAAGTA ACTCGGGACC AAATGAAGAT GTTTATACAG
CAGGAATTTA AGAAAGTTCA GAAAGTGATT GCTGATGAGG AGCAGAAGGC CCTTCATCTA
GTGGACATCC AAGAGGCAAT GGCCACAGCT CATGTGACTG AGATACTGGC AGACATCCAA
TCCCACATGG ATAGGTTGAT GACTCAGATG GCCCAAGCCA AGGAACAACT TGATACCTCT
AATGAATCAG CTGAGCCAAA GGCAGAGGGC GATGAGGAAG GACCCAGTGG TGCCAGTGAA
GAAGAGGACA CATGA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq NP_060053.2
CDS361..1395
Misc Feature(1)49..51
Misc Feature(2)889..1005
Misc Feature(3)order(895..897,904..906,961..963,979..981)
Misc Feature(4)1366..1368
Misc Feature(5)1375..1377
Exon (1)1..1029
Exon (2)1030..1107
Exon (3)1108..1347
Exon (4)1348..1367
Exon (5)1368..6063
Translation

Target ORF information:

RefSeq Version NM_017583.5
Organism Homo sapiens(Human)
Definition Homo sapiens tripartite motif containing 44 (TRIM44), mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
NM_017583.5

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
ATGGCCTCTG GAGTGGGCGC GGCCTTCGAG GAACTGCCTC ACGACGGCAC GTGTGACGAG 
TGCGAGCCCG ACGAGGCTCC GGGGGCCGAG GAAGTGTGCC GAGAATGCGG CTTCTGCTAC
TGCCGCCGCC ATGCCGAGGC GCACAGGCAG AAGTTCCTCA GTCACCATCT GGCCGAATAC
GTCCACGGCT CCCAGGCCTG GACCCCGCCA GCTGACGGAG AGGGGGCGGG GAAGGAAGAA
GCGGAGGTCA AGGTGGAGCA GGAGAGGGAG ATAGAAAGCG AGGCAGGGGA AGAGAGTGAG
TCGGAGGAAG AGAGCGAGTC AGAGGAAGAG AGCGAGACAG AGGAAGAGAG TGAGGATGAG
AGCGATGAGG AGAGTGAAGA AGACAGCGAG GAAGAAATGG AGGATGAGCA AGAAAGCGAG
GCCGAAGAAG ACAACCAAGA AGAAGGGGAA TCCGAGGCGG AGGGAGAAAC TGAGGCAGAA
AGTGAATTTG ACCCAGAAAT AGAAATGGAA GCAGAGAGAG TGGCCAAGAG GAAGTGTCCG
GACCATGGGC TTGATTTGAG TACCTATTGC CAGGAAGATA GGCAGCTCAT CTGTGTCCTG
TGTCCAGTCA TTGGGGCTCA CCAGGGCCAC CAACTCTCCA CCCTAGACGA AGCCTTTGAA
GAATTAAGAA GCAAAGACTC AGGTGGACTG AAGGCCGCTA TGATCGAATT GGTGGAAAGG
TTGAAGTTCA AGAGCTCAGA CCCTAAAGTA ACTCGGGACC AAATGAAGAT GTTTATACAG
CAGGAATTTA AGAAAGTTCA GAAAGTGATT GCTGATGAGG AGCAGAAGGC CCTTCATCTA
GTGGACATCC AAGAGGCAAT GGCCACAGCT CATGTGACTG AGATACTGGC AGACATCCAA
TCCCACATGG ATAGGTTGAT GACTCAGATG GCCCAAGCCA AGGAACAACT TGATACCTCT
AATGAATCAG CTGAGCCAAA GGCAGAGGGC GATGAGGAAG GACCCAGTGG TGCCAGTGAA
GAAGAGGACA CATGA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OHu44905
Clone ID Related Accession (Same CDS sequence) XM_006718254.1
Accession Version XM_006718254.1 Latest version! Documents for ORF clone product in dufault vector
Sequence Information ORF Nucleotide Sequence (Length: 795bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ® Seamless cloning technology
Insert Structure linear
Update Date 2016-06-06
Organism Homo sapiens(Human)
Product tripartite motif-containing protein 44 isoform X1
Comment MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000011.10) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Homo sapiens Annotation Release 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

1
61
121
181
241
301
361
421
481
541
601
661
721
781
ATGGCCTCTG GAGTGGGCGC GGCCTTCGAG GAACTGCCTC ACGACGGCAC GTGTGACGAG 
TGCGAGCCCG ACGAGGCTCC GGGGGCCGAG GAAGTGTGCC GAGAATGCGG CTTCTGCTAC
TGCCGCCGCC ATGCCGAGGC GCACAGGCAG AAGTTCCTCA GTCACCATCT GGCCGAATAC
GTCCACGGCT CCCAGGCCTG GACCCCGCCA GCTGACGGAG AGGGGGCGGG GAAGGAAGAA
GCGGAGGTCA AGGTGGAGCA GGAGAGGGAG ATAGAAAGCG AGGCAGGGGA AGAGAGTGAG
TCGGAGGAAG AGAGCGAGTC AGAGGAAGAG AGCGAGACAG AGGAAGAGAG TGAGGATGAG
AGCGATGAGG AGAGTGAAGA AGACAGCGAG GAAGAAATGG AGGATGAGCA AGAAAGCGAG
GCCGAAGAAG ACAACCAAGA AGAAGGGGAA TCCGAGGCGG AGGGAGAAAC TGAGGCAGAA
AGTGAATTTG ACCCAGAAAT AGAAATGGAA GCAGAGAGAG TGGCCAAGAG GAAGTGTCCG
GACCATGGGC TTGATTTGAG TACCTATTGC CAGGAAGATA GGCAGCTCAT CTGTGTCCTG
TGTCCAGTCA TTGGGGCTCA CCAGGGCCAC CAACTCTCCA CCCTAGACGA AGCCTTTGAA
GAATTAAGAA GCAAAGACTC AGGTGGACTG AAGGCCGCTA TGATCGAATT GGTGGAAAGG
TTGAAGTTCA AGAGCTCAGA CCCTAAAGGC GATGAGGAAG GACCCAGTGG TGCCAGTGAA
GAAGAGGACA CATGA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq XP_006718317.1
CDS421..1215
Misc Feature(1)949..1065
Misc Feature(2)order(955..957,964..966,1021..1023,1039..1041)
Translation

Target ORF information:

RefSeq Version XM_006718254.1
Organism Homo sapiens(Human)
Definition Homo sapiens tripartite motif containing 44 (TRIM44), transcript variant X1, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
XM_006718254.1

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
ATGGCCTCTG GAGTGGGCGC GGCCTTCGAG GAACTGCCTC ACGACGGCAC GTGTGACGAG 
TGCGAGCCCG ACGAGGCTCC GGGGGCCGAG GAAGTGTGCC GAGAATGCGG CTTCTGCTAC
TGCCGCCGCC ATGCCGAGGC GCACAGGCAG AAGTTCCTCA GTCACCATCT GGCCGAATAC
GTCCACGGCT CCCAGGCCTG GACCCCGCCA GCTGACGGAG AGGGGGCGGG GAAGGAAGAA
GCGGAGGTCA AGGTGGAGCA GGAGAGGGAG ATAGAAAGCG AGGCAGGGGA AGAGAGTGAG
TCGGAGGAAG AGAGCGAGTC AGAGGAAGAG AGCGAGACAG AGGAAGAGAG TGAGGATGAG
AGCGATGAGG AGAGTGAAGA AGACAGCGAG GAAGAAATGG AGGATGAGCA AGAAAGCGAG
GCCGAAGAAG ACAACCAAGA AGAAGGGGAA TCCGAGGCGG AGGGAGAAAC TGAGGCAGAA
AGTGAATTTG ACCCAGAAAT AGAAATGGAA GCAGAGAGAG TGGCCAAGAG GAAGTGTCCG
GACCATGGGC TTGATTTGAG TACCTATTGC CAGGAAGATA GGCAGCTCAT CTGTGTCCTG
TGTCCAGTCA TTGGGGCTCA CCAGGGCCAC CAACTCTCCA CCCTAGACGA AGCCTTTGAA
GAATTAAGAA GCAAAGACTC AGGTGGACTG AAGGCCGCTA TGATCGAATT GGTGGAAAGG
TTGAAGTTCA AGAGCTCAGA CCCTAAAGGC GATGAGGAAG GACCCAGTGG TGCCAGTGAA
GAAGAGGACA CATGA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

book

A novel prognostic factor TRIM44 promotes cell proliferation and migration, and inhibits apoptosis in testicular germ cell tumor.
Cancer science108(1)32-41(2017 Jan)
Yamada Y,Takayama KI,Fujimura T,Ashikari D,Obinata D,Takahashi S,Ikeda K,Kakutani S,Urano T,Fukuhara H,Homma Y,Inoue S


book

High expression of TRIM44 is associated with enhanced cell proliferation, migration, invasion, and resistance to doxorubicin in hepatocellular carcinoma.
Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine37(11)14615-14628(2016 Nov)
Zhu X,Wu Y,Miao X,Li C,Yin H,Yang S,Lu X,Liu Y,Chen Y,Shen R,Chen X,He S


book

Variants in TRIM44 Cause Aniridia by Impairing PAX6 Expression.
Human mutation36(12)1164-7(2015 Dec)
Zhang X,Qin G,Chen G,Li T,Gao L,Huang L,Zhang Y,Ouyang K,Wang Y,Pang Y,Zeng B,Yu L


book

Trim44 facilitates the migration and invasion of human lung cancer cells via the NF-κB signaling pathway.
International journal of clinical oncology20(3)508-17(2015 Jun)
Luo Q,Lin H,Ye X,Huang J,Lu S,Xu L


book

Novel function of Trim44 promotes an antiviral response by stabilizing VISA.
Journal of immunology (Baltimore, Md. : 1950)190(7)3613-9(2013 Apr)
Yang B,Wang J,Wang Y,Zhou H,Wu X,Tian Z,Sun B


 
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