Gene Symbol | WBP1L |
Entrez Gene ID | 54838 |
Full Name | WW domain binding protein 1 like |
Synonyms | C10orf26,OPA1L,OPAL1 |
General protein information |
|
Gene Type | protein-coding |
Organism | Homo sapiens(human) |
Genome | |
Disorder MIM: |
ORF » Species Summary » Homo sapiens » WBP1L cDNA ORF clone
gRNAs
Gene Symbol | WBP1L |
Entrez Gene ID | 54838 |
Full Name | WW domain binding protein 1 like |
Synonyms | C10orf26,OPA1L,OPAL1 |
General protein information |
|
Gene Type | protein-coding |
Organism | Homo sapiens(human) |
Genome | |
Disorder MIM: |
mRNA | Protein | Name |
---|---|---|
XM_011539913.2 | XP_011538215.1 | WW domain binding protein 1-like isoform X1 |
XM_017016360.1 | XP_016871849.1 | WW domain binding protein 1-like isoform X2 |
NM_017787.4 | NP_060257.4 | WW domain binding protein 1-like isoform 2 |
NM_001083913.1 | NP_001077382.1 | WW domain binding protein 1-like isoform 1 precursor |
NM_001083913.2 | NP_001077382.1 | WW domain binding protein 1-like isoform 1 precursor |
NM_017787.5 | NP_060257.4 | WW domain binding protein 1-like isoform 2 |
Bos taurus (cattle) | C26H10orf26 | XP_002698502.1 |
Mus musculus (house mouse) | Wbp1l | NP_001171283.1 |
Danio rerio (zebrafish) | wbp1la | NP_001037798.1 |
Rattus norvegicus (Norway rat) | Wbp1l | NP_001120956.1 |
Canis lupus familiaris (dog) | WBP1L | XP_005637734.1 |
Xenopus tropicalis (tropical clawed frog) | wbp1l | NP_001090795.1 |
WBP1L | XP_001113211.2 | |
Homo sapiens (human) | WBP1L | NP_001077382.1 |
Gallus gallus (chicken) | C6H10ORF26 | XP_004942301.1 |
Biological insights from 108 schizophrenia-associated genetic loci.
Nature511(7510)421-7(2014 Jul)
Genome-wide association analysis identifies 13 new risk loci for schizophrenia.
Ripke S, O'Dushlaine C, Chambert K, Moran JL, K?hler AK, Akterin S, Bergen SE, Collins AL, Crowley JJ, Fromer M, Kim Y, Lee SH, Magnusson PK, Sanchez N, Stahl EA, Williams S, Wray NR, Xia K, Bettella F, Borglum AD, Bulik-Sullivan BK, Cormican P, Craddock N, de Leeuw C, Durmishi N, Gill M, Golimbet V, Hamshere ML, Holmans P, Hougaard DM, Kendler KS, Lin K, Morris DW, Mors O, Mortensen PB, Neale BM, O'Neill FA, Owen MJ, Milovancevic MP, Posthuma D, Powell J, Richards AL, Riley BP, Ruderfer D, Rujescu D, Sigurdsson E, Silagadze T, Smit AB, Stefansson H, Steinberg S, Suvisaari J, Tosato S, Verhage M, Walters JT, , Levinson DF, Gejman PV, Kendler KS, Laurent C, Mowry BJ, O'Donovan MC, Owen MJ, Pulver AE, Riley BP, Schwab SG, Wildenauer DB, Dudbridge F, Holmans P, Shi J, Albus M, Alexander M, Campion D, Cohen D, Dikeos D, Duan J, Eichhammer P, Godard S, Hansen M, Lerer FB, Liang KY, Maier W, Mallet J, Nertney DA, Nestadt G, Norton N, O'Neill FA, Papadimitriou GN, Ribble R, Sanders AR, Silverman JM, Walsh D, Williams NM, Wormley B, , Arranz MJ, Bakker S, Bender S, Bramon E, Collier D, Crespo-Facorro B, Hall J, Iyegbe C, Jablensky A, Kahn RS, Kalaydjieva L, Lawrie S, Lewis CM, Lin K, Linszen DH, Mata I, McIntosh A, Murray RM, Ophoff RA, Powell J, Rujescu D, Van Os J, Walshe M, Weisbrod M, Wiersma D, , Donnelly P, Barroso I, Blackwell JM, Bramon E, Brown MA, Casas JP, Corvin AP, Deloukas P, Duncanson A, Jankowski J, Markus HS, Mathew CG, Palmer CN, Plomin R, Rautanen A, Sawcer SJ, Trembath RC, Viswanathan AC, Wood NW, Spencer CC, Band G, Bellenguez C, Freeman C, Hellenthal G, Giannoulatou E, Pirinen M, Pearson RD, Strange A, Su Z, Vukcevic D, Donnelly P, Langford C, Hunt SE, Edkins S, Gwilliam R, Blackburn H, Bumpstead SJ, Dronov S, Gillman M, Gray E, Hammond N, Jayakumar A, McCann OT, Liddle J, Potter SC, Ravindrarajah R, Ricketts M, Tashakkori-Ghanbaria A, Waller MJ, Weston P, Widaa S, Whittaker P, Barroso I, Deloukas P, Mathew CG, Blackwell JM, Brown MA, Corvin AP, McCarthy MI, Spencer CC, Bramon E, Corvin AP, O'Donovan MC, Stefansson K, Scolnick E, Purcell S, McCarroll SA, Sklar P, Hultman CM, Sullivan PF
Nature genetics45(10)1150-9(2013 Oct)
Identification of 23 new prostate cancer susceptibility loci using the iCOGS custom genotyping array.
Eeles RA, Olama AA, Benlloch S, Saunders EJ, Leongamornlert DA, Tymrakiewicz M, Ghoussaini M, Luccarini C, Dennis J, Jugurnauth-Little S, Dadaev T, Neal DE, Hamdy FC, Donovan JL, Muir K, Giles GG, Severi G, Wiklund F, Gronberg H, Haiman CA, Schumacher F, Henderson BE, Le Marchand L, Lindstrom S, Kraft P, Hunter DJ, Gapstur S, Chanock SJ, Berndt SI, Albanes D, Andriole G, Schleutker J, Weischer M, Canzian F, Riboli E, Key TJ, Travis RC, Campa D, Ingles SA, John EM, Hayes RB, Pharoah PD, Pashayan N, Khaw KT, Stanford JL, Ostrander EA, Signorello LB, Thibodeau SN, Schaid D, Maier C, Vogel W, Kibel AS, Cybulski C, Lubinski J, Cannon-Albright L, Brenner H, Park JY, Kaneva R, Batra J, Spurdle AB, Clements JA, Teixeira MR, Dicks E, Lee A, Dunning AM, Baynes C, Conroy D, Maranian MJ, Ahmed S, Govindasami K, Guy M, Wilkinson RA, Sawyer EJ, Morgan A, Dearnaley DP, Horwich A, Huddart RA, Khoo VS, Parker CC, Van As NJ, Woodhouse CJ, Thompson A, Dudderidge T, Ogden C, Cooper CS, Lophatananon A, Cox A, Southey MC, Hopper JL, English DR, Aly M, Adolfsson J, Xu J, Zheng SL, Yeager M, Kaaks R, Diver WR, Gaudet MM, Stern MC, Corral R, Joshi AD, Shahabi A, Wahlfors T, Tammela TL, Auvinen A, Virtamo J, Klarskov P, Nordestgaard BG, R?der MA, Nielsen SF, Bojesen SE, Siddiq A, Fitzgerald LM, Kolb S, Kwon EM, Karyadi DM, Blot WJ, Zheng W, Cai Q, McDonnell SK, Rinckleb AE, Drake B, Colditz G, Wokolorczyk D, Stephenson RA, Teerlink C, Muller H, Rothenbacher D, Sellers TA, Lin HY, Slavov C, Mitev V, Lose F, Srinivasan S, Maia S, Paulo P, Lange E, Cooney KA, Antoniou AC, Vincent D, Bacot F, Tessier DC, , , , , , Kote-Jarai Z, Easton DF
Nature genetics45(4)385-91, 391e1-2(2013 Apr)
Unexpected diversity in Shisa-like proteins suggests the importance of their roles as transmembrane adaptors.
Pei J, Grishin NV
Cellular signalling24(3)758-69(2012 Mar)
Identification of intrahepatic cholangiocarcinoma related genes by comparison with normal liver tissues using expressed sequence tags.
Wang AG, Yoon SY, Oh JH, Jeon YJ, Kim M, Kim JM, Byun SS, Yang JO, Kim JH, Kim DG, Yeom YI, Yoo HS, Kim YS, Kim NS
Biochemical and biophysical research communications345(3)1022-32(2006 Jul)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
OPAL1 expression may not be an independent prognostic feature in childhood ALL, and its previously reported prognostic impact appears to be treatment dependent.
Title: Expression of the outcome predictor in acute leukemia 1 (OPAL1) gene is not an independent prognostic factor in patients treated according to COALL or St Jude protocols.
Observational study of gene-disease association. (HuGE Navigator)
Title: A scan of chromosome 10 identifies a novel locus showing strong association with late-onset Alzheimer disease.
The following WBP1L gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the WBP1L cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
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CloneID | OHu25925![]() |
|
Clone ID Related Accession (Same CDS sequence) | NM_017787.4 , NM_017787.5 | |
Accession Version | NM_017787.4 | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1029bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | ![]() |
Clone information | Clone Map | ![]() |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-02-16 | |
Organism | Homo sapiens(human) | |
Product | WW domain binding protein 1-like isoform 2 | |
Comment | Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from DA797839.1, AY656171.1 and AL358790.22. On Apr 11, 2007 this sequence version replaced NM_017787.3. Transcript Variant: This variant (2) has an alternate exon at its 5' end, compared to variant 1, resulting in a unique 5' UTR and use of a distinct translation initiation codon, compared to variant 1. The encoded protein (isoform 2) is shorter than isoform 1. ##Evidence-Data-START## Transcript exon combination :: AY656171.1, SRR1803617.18062.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end. |
1 | ATGCCTTTCC TTTTGGGTCT TAGACAGGAT AAGGAAGCCT GTGTGGGTAC CAACAATCAA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_060257.4 |
CDS | 261..1289 |
Translation |
Target ORF information:
Target ORF information:
|
![]() |
1 | ATGCCTTTCC TTTTGGGTCT TAGACAGGAT AAGGAAGCCT GTGTGGGTAC CAACAATCAA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OHu25925![]() |
|
Clone ID Related Accession (Same CDS sequence) | NM_017787.4 , NM_017787.5 | |
Accession Version | NM_017787.5 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1029bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | ![]() |
Clone information | Clone Map | ![]() |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-05-30 | |
Organism | Homo sapiens(human) | |
Product | WW domain binding protein 1-like isoform 2 | |
Comment | Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from DA797839.1, AY656171.1 and AL358790.22. On May 31, 2019 this sequence version replaced NM_017787.4. Transcript Variant: This variant (2) has an alternate exon at its 5' end, compared to variant 1, resulting in a unique 5' UTR and use of a distinct translation initiation codon, compared to variant 1. The encoded protein (isoform 2) is shorter than isoform 1. ##Evidence-Data-START## Transcript exon combination :: AY656171.1, SRR1803617.18062.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end. |
1 | ATGCCTTTCC TTTTGGGTCT TAGACAGGAT AAGGAAGCCT GTGTGGGTAC CAACAATCAA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_060257.4 |
CDS | 171..1199 |
Translation |
Target ORF information:
Target ORF information:
|
![]() |
1 | ATGCCTTTCC TTTTGGGTCT TAGACAGGAT AAGGAAGCCT GTGTGGGTAC CAACAATCAA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OHu25939![]() |
|
Clone ID Related Accession (Same CDS sequence) | NM_001083913.1 , NM_001083913.2 | |
Accession Version | NM_001083913.1 | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1092bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | ![]() |
Clone information | Clone Map | ![]() |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2017-10-01 | |
Organism | Homo sapiens(human) | |
Product | WW domain binding protein 1-like isoform 1 precursor | |
Comment | Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AL391121.29, CX163170.1, AL358790.22 and AY656171.1. Transcript Variant: This variant (1) encodes the longer isoform (1). ##Evidence-Data-START## Transcript exon combination :: SRR1803616.34236.1, SRR1803613.124051.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end. |
1 | ATGGAGAGGA GAAGGCTCCT GGGTGGCATG GCGCTCCTGC TCCTCCAGGC GCTGCCCAGC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_001077382.1 |
CDS | 85..1176 |
Translation |
Target ORF information:
Target ORF information:
|
![]() |
1 | ATGGAGAGGA GAAGGCTCCT GGGTGGCATG GCGCTCCTGC TCCTCCAGGC GCTGCCCAGC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OHu25939![]() |
|
Clone ID Related Accession (Same CDS sequence) | NM_001083913.1 , NM_001083913.2 | |
Accession Version | NM_001083913.2 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1092bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | ![]() |
Clone information | Clone Map | ![]() |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-05-03 | |
Organism | Homo sapiens(human) | |
Product | WW domain binding protein 1-like isoform 1 precursor | |
Comment | Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AL391121.29, CX163170.1, AL358790.22 and AY656171.1. On Nov 23, 2018 this sequence version replaced NM_001083913.1. Transcript Variant: This variant (1) encodes the longer isoform (1). ##Evidence-Data-START## Transcript exon combination :: SRR1163657.62749.1, SRR1803616.34236.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000448841.7/ ENSP00000414721.1 RefSeq Select criteria :: based on conservation, expression, longest protein ##RefSeq-Attributes-END## COMPLETENESS: full length. |
1 | ATGGAGAGGA GAAGGCTCCT GGGTGGCATG GCGCTCCTGC TCCTCCAGGC GCTGCCCAGC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_001077382.1 |
CDS | 107..1198 |
Translation |
Target ORF information:
Target ORF information:
|
![]() |
1 | ATGGAGAGGA GAAGGCTCCT GGGTGGCATG GCGCTCCTGC TCCTCCAGGC GCTGCCCAGC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OHu68669 | |
Clone ID Related Accession (Same CDS sequence) | XM_011539913.2 | |
Accession Version | XM_011539913.2 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1065bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | ![]() |
Clone information | Clone Map | ![]() |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-12-05 | |
Organism | Homo sapiens(human) | |
Product | WW domain binding protein 1-like isoform X1 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000010.11) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 6, 2016 this sequence version replaced XM_011539913.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGTCTTATT CATCTTTGTA TCCCTTGAAC CCAACACAAT GCTTGGCACA AAGACAGCGT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_011538215.1 |
CDS | 16..1080 |
Translation |
Target ORF information:
Target ORF information:
|
![]() |
1 | ATGTCTTATT CATCTTTGTA TCCCTTGAAC CCAACACAAT GCTTGGCACA AAGACAGCGT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OHu91490 | |
Clone ID Related Accession (Same CDS sequence) | XM_017016360.1 | |
Accession Version | XM_017016360.1 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 780bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | ![]() |
Clone information | Clone Map | ![]() |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-12-05 | |
Organism | Homo sapiens(human) | |
Product | WW domain binding protein 1-like isoform X2 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000010.11) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGACCAGTG CAGTAATTTC TCCTTCCTAC CTCCCCATTT TAGGGTTTTT GCCAAACTAT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_016871849.1 |
CDS | 1920..2699 |
Translation |
Target ORF information:
Target ORF information:
|
![]() |
1 | ATGACCAGTG CAGTAATTTC TCCTTCCTAC CTCCCCATTT TAGGGTTTTT GCCAAACTAT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
Biological insights from 108 schizophrenia-associated genetic loci. |
Genome-wide association analysis identifies 13 new risk loci for schizophrenia. |
Identification of 23 new prostate cancer susceptibility loci using the iCOGS custom genotyping array. |
Unexpected diversity in Shisa-like proteins suggests the importance of their roles as transmembrane adaptors. |
Identification of intrahepatic cholangiocarcinoma related genes by comparison with normal liver tissues using expressed sequence tags. |