LGI2 cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Gene Symbol	LGI2
Entrez Gene ID	55203
Full Name	leucine rich repeat LGI family member 2
Synonyms	LGIL2
General protein information	Preferred Names leucine rich repeat LGI family member 2 Names leucine-rich repeat LGI family member 2 LGI1-like protein 2 leucine-rich glioma-inactivated protein 2 leucine-rich, glioma inactivated 2
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 4 Map Location: 4p15.2
Disorder MIM:	608301

mRNA and Protein(s)

mRNA	Protein	Name
NM_018176.3	NP_060646.2	leucine-rich repeat LGI family member 2 precursor
XM_017008356.1	XP_016863845.1	leucine-rich repeat LGI family member 2 isoform X2
NM_018176.4	NP_060646.2	leucine-rich repeat LGI family member 2 precursor
XM_011513850.2	XP_011512152.1	leucine-rich repeat LGI family member 2 isoform X1

Pathways from BioSystems

Homologies

Gallus gallus (chicken)	LGI2	NP_001244245.1
Pan troglodytes (chimpanzee)	LGI2	NP_001037843.1
	LGI2	XP_001082016.1
Mus musculus (house mouse)	Lgi2	NP_659194.1
Homo sapiens (human)	LGI2	NP_060646.2
Bos taurus (cattle)	LGI2	NP_001179745.1
Xenopus tropicalis (tropical clawed frog)	lgi2	NP_001096394.1
Canis lupus familiaris (dog)	LGI2	XP_545971.3
Rattus norvegicus (Norway rat)	Lgi2	NP_001100689.2

Gene Ontology
Bibliography

Related articles in PubMed

Similarity of molecular phenotype between known epilepsy gene LGI1 and disease candidate gene LGI2.
Limviphuvadh V, Chua LL, Rahim RA, Eisenhaber F, Maurer-Stroh S, Adhikari S
BMC biochemistry1139(2010 Sep)

Is LGI2 the candidate gene for partial epilepsy with pericentral spikes?
Limviphuvadh V, Chua LL, Eisenhaber F, Adhikari S, Maurer-Stroh S
Journal of bioinformatics and computational biology8(1)117-27(2010 Feb)

Using gene-history and expression analyses to assess the involvement of LGI genes in human disorders.
Gu W, Gibert Y, Wirth T, Elischer A, Bloch W, Meyer A, Steinlein OK, Begemann G
Molecular biology and evolution22(11)2209-16(2005 Nov)

A two-dimensional electrophoresis reference map of human ovary.
Wang L, Zhu YF, Guo XJ, Huo R, Ma X, Lin M, Zhou ZM, Sha JH
Journal of molecular medicine (Berlin, Germany)83(10)812-21(2005 Oct)

The novel EPTP repeat defines a superfamily of proteins implicated in epileptic disorders.
Staub E, P?rez-Tur J, Siebert R, Nobile C, Moschonas NK, Deloukas P, Hinzmann B
Trends in biochemical sciences27(9)441-4(2002 Sep)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The similarity of LGI2 share a common molecular disease mechanism causing genotypically distinct but phenotypically related forms of epilepsy.
Title: Similarity of molecular phenotype between known epilepsy gene LGI1 and disease candidate gene LGI2.

protein sequence analysis and patient-specific chromosomal deletions are provided for LGI2 as the prime candidate gene for partial epilepsy with pericentral spikes among the 52 genes known at locus 4p15
Title: Is LGI2 the candidate gene for partial epilepsy with pericentral spikes?

The following LGI2 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the LGI2 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

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***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu02722	NM_018176.4 Latest version!	Homo sapiens leucine rich repeat LGI family member 2 (LGI2), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$219.50-$307.30 $439.00
OHu69152	XM_011513850.2 Latest version!	Homo sapiens leucine rich repeat LGI family member 2 (LGI2), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$139.30 $199.00
OHu95271	XM_017008356.1 Latest version!	Homo sapiens leucine rich repeat LGI family member 2 (LGI2), transcript variant X2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$139.30 $199.00
View Old Accession Versions >>
OHu02722	NM_018176.3	Homo sapiens leucine rich repeat LGI family member 2 (LGI2), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$307.30 $439.00
Hide Old Accession Versions >>

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

LGI2 ( NM_018176.4 ) cDNA ORF clone, Homo sapiens(human) -> NP_060646.2 Homo sapiens leucine rich repeat LGI family member 2 (LGI2), mRNA.

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CloneID	OHu02722
Clone ID Related Accession (Same CDS sequence)	NM_018176.3 , NM_018176.4
Accession Version	NM_018176.4 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1638bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-29
Organism	Homo sapiens(human)
Product	leucine-rich repeat LGI family member 2 precursor
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AC113614.4 and BC101761.1. On Nov 23, 2018 this sequence version replaced NM_018176.3. Sequence Note: The RefSeq transcript and protein were derived from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The extent of this RefSeq transcript is supported by transcript alignments. ##Evidence-Data-START## Transcript exon combination :: AB067503.1, SRR1803617.203015.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000382114.9/ ENSP00000371548.4 RefSeq Select criteria :: based on conservation, expression, longest protein ##RefSeq-Attributes-END## COMPLETENESS: full length.

ATGGCGCTGC GGAGAGGCGG CTGCGGAGCG CTCGGGCTGC TGCTGCTGCT GCTGGGCGCC 
GCGTGCCTGA TACCGCGGAG CGCGCAGGTG AGGCGGCTGG CGCGCTGCCC CGCCACTTGC 
AGCTGTACCA AGGAGTCTAT CATCTGCGTG GGCTCTTCCT GGGTGCCCAG GATCGTGCCG 
GGCGACATCA GCTCCCTGAG CCTGGTAAAT GGGACGTTTT CAGAAATCAA GGACCGAATG 
TTTTCCCATC TGCCTTCTCT GCAGCTGCTA TTGCTGAATT CTAACTCATT CACGATCATC 
CGGGATGATG CTTTTGCTGG ACTTTTTCAT CTTGAATACC TGTTCATTGA AGGGAACAAA 
ATAGAAACCA TTTCAAGAAA TGCCTTTCGT GGCCTCCGTG ACCTGACTCA CCTTTCTTTG 
GCCAATAACC ACATAAAAGC ACTACCAAGG GATGTCTTCA GTGATTTAGA CTCTCTGATT 
GAACTAGATT TGAGGGGTAA TAAATTTGAA TGTGACTGCA AAGCCAAGTG GCTATACCTG 
TGGTTGAAGA TGACAAATTC CACCGTTTCT GATGTGCTGT GTATTGGTCC ACCAGAGTAT 
CAGGAAAAGA AGCTAAATGA CGTGACCAGC TTTGACTATG AATGCACAAC TACAGATTTT 
GTTGTTCATC AGACTTTACC CTACCAGTCG GTTTCAGTGG ATACGTTCAA CTCCAAGAAC 
GATGTGTACG TGGCCATCGC GCAGCCCAGC ATGGAGAACT GCATGGTGCT GGAGTGGGAC 
CACATTGAAA TGAATTTCCG GAGCTATGAC AACATTACAG GTCAGTCCAT CGTGGGCTGT 
AAGGCCATTC TCATCGATGA TCAGGTCTTT GTGGTGGTAG CCCAGCTCTT CGGTGGCTCT 
CACATTTACA AATACGACGA GAGTTGGACC AAATTTGTCA AATTCCAAGA CATAGAGGTC 
TCTCGCATTT CCAAGCCCAA TGACATCGAG CTGTTTCAGA TCGACGACGA GACGTTCTTT 
GTCATCGCAG ACAGCTCAAA GGCTGGTCTG TCCACAGTTT ATAAATGGAA CAGCAAAGGA 
TTCTATTCTT ACCAGTCACT GCACGAGTGG TTCAGGGACA CGGATGCGGA GTTTGTTGAT 
ATCGATGGAA AATCGCATCT CATCCTGTCC AGCCGCTCCC AGGTCCCCAT CATCCTCCAG 
TGGAATAAAA GCTCTAAGAA GTTTGTCCCC CATGGTGACA TCCCCAACAT GGAGGACGTA 
CTGGCTGTGA AGAGCTTCCG AATGCAAAAT ACCCTCTACC TTTCCCTTAC CCGCTTCATC 
GGGGACTCCC GGGTCATGAG GTGGAACAGT AAGCAGTTTG TGGAGATCCA AGCTCTTCCA 
TCCCGGGGGG CCATGACCCT GCAGCCCTTT TCTTTTAAAG ATAATCACTA CCTGGCCCTG 
GGGAGTGACT ATACATTCTC TCAGATATAC CAGTGGGATA AAGAGAAGCA GCTATTCAAA 
AAGTTTAAGG AGATTTACGT GCAGGCGCCT CGTTCATTCA CAGCTGTCTC CACCGACAGG 
AGAGATTTCT TTTTTGCATC CAGTTTCAAA GGGAAAACAA AGATTTTTGA ACATATAATT 
GTTGACTTAA GTTTGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_060646.2
CDS	254..1891
Translation	MALRRGGCGALGLLLLLLGAACLIPRSAQVRRLARCPATCSCTKESIICVGSSWVPRIVPGDISSLSLVNGTFSEIKDRMFSHLPSLQLLLLNSNSFTIIRDDAFAGLFHLEYLFIEGNKIETISRNAFRGLRDLTHLSLANNHIKALPRDVFSDLDSLIELDLRGNKFECDCKAKWLYLWLKMTNSTVSDVLCIGPPEYQEKKLNDVTSFDYECTTTDFVVHQTLPYQSVSVDTFNSKNDVYVAIAQPSMENCMVLEWDHIEMNFRSYDNITGQSIVGCKAILIDDQVFVVVAQLFGGSHIYKYDESWTKFVKFQDIEVSRISKPNDIELFQIDDETFFVIADSSKAGLSTVYKWNSKGFYSYQSLHEWFRDTDAEFVDIDGKSHLILSSRSQVPIILQWNKSSKKFVPHGDIPNMEDVLAVKSFRMQNTLYLSLTRFIGDSRVMRWNSKQFVEIQALPSRGAMTLQPFSFKDNHYLALGSDYTFSQIYQWDKEKQLFKKFKEIYVQAPRSFTAVSTDRRDFFFASSFKGKTKIFEHIIVDLSL

Target ORF information:

RefSeq Version	NM_018176.4
Organism	Homo sapiens(human)
Definition	Homo sapiens leucine rich repeat LGI family member 2 (LGI2), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_018176.4

ORF Insert Sequence:

ATGGCGCTGC GGAGAGGCGG CTGCGGAGCG CTCGGGCTGC TGCTGCTGCT GCTGGGCGCC 
GCGTGCCTGA TACCGCGGAG CGCGCAGGTG AGGCGGCTGG CGCGCTGCCC CGCCACTTGC 
AGCTGTACCA AGGAGTCTAT CATCTGCGTG GGCTCTTCCT GGGTGCCCAG GATCGTGCCG 
GGCGACATCA GCTCCCTGAG CCTGGTAAAT GGGACGTTTT CAGAAATCAA GGACCGAATG 
TTTTCCCATC TGCCTTCTCT GCAGCTGCTA TTGCTGAATT CTAACTCATT CACGATCATC 
CGGGATGATG CTTTTGCTGG ACTTTTTCAT CTTGAATACC TGTTCATTGA AGGGAACAAA 
ATAGAAACCA TTTCAAGAAA TGCCTTTCGT GGCCTCCGTG ACCTGACTCA CCTTTCTTTG 
GCCAATAACC ACATAAAAGC ACTACCAAGG GATGTCTTCA GTGATTTAGA CTCTCTGATT 
GAACTAGATT TGAGGGGTAA TAAATTTGAA TGTGACTGCA AAGCCAAGTG GCTATACCTG 
TGGTTGAAGA TGACAAATTC CACCGTTTCT GATGTGCTGT GTATTGGTCC ACCAGAGTAT 
CAGGAAAAGA AGCTAAATGA CGTGACCAGC TTTGACTATG AATGCACAAC TACAGATTTT 
GTTGTTCATC AGACTTTACC CTACCAGTCG GTTTCAGTGG ATACGTTCAA CTCCAAGAAC 
GATGTGTACG TGGCCATCGC GCAGCCCAGC ATGGAGAACT GCATGGTGCT GGAGTGGGAC 
CACATTGAAA TGAATTTCCG GAGCTATGAC AACATTACAG GTCAGTCCAT CGTGGGCTGT 
AAGGCCATTC TCATCGATGA TCAGGTCTTT GTGGTGGTAG CCCAGCTCTT CGGTGGCTCT 
CACATTTACA AATACGACGA GAGTTGGACC AAATTTGTCA AATTCCAAGA CATAGAGGTC 
TCTCGCATTT CCAAGCCCAA TGACATCGAG CTGTTTCAGA TCGACGACGA GACGTTCTTT 
GTCATCGCAG ACAGCTCAAA GGCTGGTCTG TCCACAGTTT ATAAATGGAA CAGCAAAGGA 
TTCTATTCTT ACCAGTCACT GCACGAGTGG TTCAGGGACA CGGATGCGGA GTTTGTTGAT 
ATCGATGGAA AATCGCATCT CATCCTGTCC AGCCGCTCCC AGGTCCCCAT CATCCTCCAG 
TGGAATAAAA GCTCTAAGAA GTTTGTCCCC CATGGTGACA TCCCCAACAT GGAGGACGTA 
CTGGCTGTGA AGAGCTTCCG AATGCAAAAT ACCCTCTACC TTTCCCTTAC CCGCTTCATC 
GGGGACTCCC GGGTCATGAG GTGGAACAGT AAGCAGTTTG TGGAGATCCA AGCTCTTCCA 
TCCCGGGGGG CCATGACCCT GCAGCCCTTT TCTTTTAAAG ATAATCACTA CCTGGCCCTG 
GGGAGTGACT ATACATTCTC TCAGATATAC CAGTGGGATA AAGAGAAGCA GCTATTCAAA 
AAGTTTAAGG AGATTTACGT GCAGGCGCCT CGTTCATTCA CAGCTGTCTC CACCGACAGG 
AGAGATTTCT TTTTTGCATC CAGTTTCAAA GGGAAAACAA AGATTTTTGA ACATATAATT 
GTTGACTTAA GTTTGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

LGI2 ( NM_018176.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_060646.2 Homo sapiens leucine rich repeat LGI family member 2 (LGI2), mRNA.

Price & Availability↑

CloneID	OHu02722
Clone ID Related Accession (Same CDS sequence)	NM_018176.3 , NM_018176.4
Accession Version	NM_018176.3	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1638bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2017-10-01
Organism	Homo sapiens(human)
Product	leucine-rich repeat LGI family member 2 precursor
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from BC101761.1 and AC113614.4. On Aug 2, 2008 this sequence version replaced NM_018176.2. Sequence Note: The RefSeq transcript and protein were derived from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The extent of this RefSeq transcript is supported by transcript alignments. ##Evidence-Data-START## Transcript exon combination :: AB067503.1, AJ487516.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END##

ATGGCGCTGC GGAGAGGCGG CTGCGGAGCG CTCGGGCTGC TGCTGCTGCT GCTGGGCGCC 
GCGTGCCTGA TACCGCGGAG CGCGCAGGTG AGGCGGCTGG CGCGCTGCCC CGCCACTTGC 
AGCTGTACCA AGGAGTCTAT CATCTGCGTG GGCTCTTCCT GGGTGCCCAG GATCGTGCCG 
GGCGACATCA GCTCCCTGAG CCTGGTAAAT GGGACGTTTT CAGAAATCAA GGACCGAATG 
TTTTCCCATC TGCCTTCTCT GCAGCTGCTA TTGCTGAATT CTAACTCATT CACGATCATC 
CGGGATGATG CTTTTGCTGG ACTTTTTCAT CTTGAATACC TGTTCATTGA AGGGAACAAA 
ATAGAAACCA TTTCAAGAAA TGCCTTTCGT GGCCTCCGTG ACCTGACTCA CCTTTCTTTG 
GCCAATAACC ACATAAAAGC ACTACCAAGG GATGTCTTCA GTGATTTAGA CTCTCTGATT 
GAACTAGATT TGAGGGGTAA TAAATTTGAA TGTGACTGCA AAGCCAAGTG GCTATACCTG 
TGGTTGAAGA TGACAAATTC CACCGTTTCT GATGTGCTGT GTATTGGTCC ACCAGAGTAT 
CAGGAAAAGA AGCTAAATGA CGTGACCAGC TTTGACTATG AATGCACAAC TACAGATTTT 
GTTGTTCATC AGACTTTACC CTACCAGTCG GTTTCAGTGG ATACGTTCAA CTCCAAGAAC 
GATGTGTACG TGGCCATCGC GCAGCCCAGC ATGGAGAACT GCATGGTGCT GGAGTGGGAC 
CACATTGAAA TGAATTTCCG GAGCTATGAC AACATTACAG GTCAGTCCAT CGTGGGCTGT 
AAGGCCATTC TCATCGATGA TCAGGTCTTT GTGGTGGTAG CCCAGCTCTT CGGTGGCTCT 
CACATTTACA AATACGACGA GAGTTGGACC AAATTTGTCA AATTCCAAGA CATAGAGGTC 
TCTCGCATTT CCAAGCCCAA TGACATCGAG CTGTTTCAGA TCGACGACGA GACGTTCTTT 
GTCATCGCAG ACAGCTCAAA GGCTGGTCTG TCCACAGTTT ATAAATGGAA CAGCAAAGGA 
TTCTATTCTT ACCAGTCACT GCACGAGTGG TTCAGGGACA CGGATGCGGA GTTTGTTGAT 
ATCGATGGAA AATCGCATCT CATCCTGTCC AGCCGCTCCC AGGTCCCCAT CATCCTCCAG 
TGGAATAAAA GCTCTAAGAA GTTTGTCCCC CATGGTGACA TCCCCAACAT GGAGGACGTA 
CTGGCTGTGA AGAGCTTCCG AATGCAAAAT ACCCTCTACC TTTCCCTTAC CCGCTTCATC 
GGGGACTCCC GGGTCATGAG GTGGAACAGT AAGCAGTTTG TGGAGATCCA AGCTCTTCCA 
TCCCGGGGGG CCATGACCCT GCAGCCCTTT TCTTTTAAAG ATAATCACTA CCTGGCCCTG 
GGGAGTGACT ATACATTCTC TCAGATATAC CAGTGGGATA AAGAGAAGCA GCTATTCAAA 
AAGTTTAAGG AGATTTACGT GCAGGCGCCT CGTTCATTCA CAGCTGTCTC CACCGACAGG 
AGAGATTTCT TTTTTGCATC CAGTTTCAAA GGGAAAACAA AGATTTTTGA ACATATAATT 
GTTGACTTAA GTTTGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_060646.2
CDS	100..1737
Translation	MALRRGGCGALGLLLLLLGAACLIPRSAQVRRLARCPATCSCTKESIICVGSSWVPRIVPGDISSLSLVNGTFSEIKDRMFSHLPSLQLLLLNSNSFTIIRDDAFAGLFHLEYLFIEGNKIETISRNAFRGLRDLTHLSLANNHIKALPRDVFSDLDSLIELDLRGNKFECDCKAKWLYLWLKMTNSTVSDVLCIGPPEYQEKKLNDVTSFDYECTTTDFVVHQTLPYQSVSVDTFNSKNDVYVAIAQPSMENCMVLEWDHIEMNFRSYDNITGQSIVGCKAILIDDQVFVVVAQLFGGSHIYKYDESWTKFVKFQDIEVSRISKPNDIELFQIDDETFFVIADSSKAGLSTVYKWNSKGFYSYQSLHEWFRDTDAEFVDIDGKSHLILSSRSQVPIILQWNKSSKKFVPHGDIPNMEDVLAVKSFRMQNTLYLSLTRFIGDSRVMRWNSKQFVEIQALPSRGAMTLQPFSFKDNHYLALGSDYTFSQIYQWDKEKQLFKKFKEIYVQAPRSFTAVSTDRRDFFFASSFKGKTKIFEHIIVDLSL

Target ORF information:

RefSeq Version	NM_018176.3
Organism	Homo sapiens(human)
Definition	Homo sapiens leucine rich repeat LGI family member 2 (LGI2), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_018176.3

ORF Insert Sequence:

ATGGCGCTGC GGAGAGGCGG CTGCGGAGCG CTCGGGCTGC TGCTGCTGCT GCTGGGCGCC 
GCGTGCCTGA TACCGCGGAG CGCGCAGGTG AGGCGGCTGG CGCGCTGCCC CGCCACTTGC 
AGCTGTACCA AGGAGTCTAT CATCTGCGTG GGCTCTTCCT GGGTGCCCAG GATCGTGCCG 
GGCGACATCA GCTCCCTGAG CCTGGTAAAT GGGACGTTTT CAGAAATCAA GGACCGAATG 
TTTTCCCATC TGCCTTCTCT GCAGCTGCTA TTGCTGAATT CTAACTCATT CACGATCATC 
CGGGATGATG CTTTTGCTGG ACTTTTTCAT CTTGAATACC TGTTCATTGA AGGGAACAAA 
ATAGAAACCA TTTCAAGAAA TGCCTTTCGT GGCCTCCGTG ACCTGACTCA CCTTTCTTTG 
GCCAATAACC ACATAAAAGC ACTACCAAGG GATGTCTTCA GTGATTTAGA CTCTCTGATT 
GAACTAGATT TGAGGGGTAA TAAATTTGAA TGTGACTGCA AAGCCAAGTG GCTATACCTG 
TGGTTGAAGA TGACAAATTC CACCGTTTCT GATGTGCTGT GTATTGGTCC ACCAGAGTAT 
CAGGAAAAGA AGCTAAATGA CGTGACCAGC TTTGACTATG AATGCACAAC TACAGATTTT 
GTTGTTCATC AGACTTTACC CTACCAGTCG GTTTCAGTGG ATACGTTCAA CTCCAAGAAC 
GATGTGTACG TGGCCATCGC GCAGCCCAGC ATGGAGAACT GCATGGTGCT GGAGTGGGAC 
CACATTGAAA TGAATTTCCG GAGCTATGAC AACATTACAG GTCAGTCCAT CGTGGGCTGT 
AAGGCCATTC TCATCGATGA TCAGGTCTTT GTGGTGGTAG CCCAGCTCTT CGGTGGCTCT 
CACATTTACA AATACGACGA GAGTTGGACC AAATTTGTCA AATTCCAAGA CATAGAGGTC 
TCTCGCATTT CCAAGCCCAA TGACATCGAG CTGTTTCAGA TCGACGACGA GACGTTCTTT 
GTCATCGCAG ACAGCTCAAA GGCTGGTCTG TCCACAGTTT ATAAATGGAA CAGCAAAGGA 
TTCTATTCTT ACCAGTCACT GCACGAGTGG TTCAGGGACA CGGATGCGGA GTTTGTTGAT 
ATCGATGGAA AATCGCATCT CATCCTGTCC AGCCGCTCCC AGGTCCCCAT CATCCTCCAG 
TGGAATAAAA GCTCTAAGAA GTTTGTCCCC CATGGTGACA TCCCCAACAT GGAGGACGTA 
CTGGCTGTGA AGAGCTTCCG AATGCAAAAT ACCCTCTACC TTTCCCTTAC CCGCTTCATC 
GGGGACTCCC GGGTCATGAG GTGGAACAGT AAGCAGTTTG TGGAGATCCA AGCTCTTCCA 
TCCCGGGGGG CCATGACCCT GCAGCCCTTT TCTTTTAAAG ATAATCACTA CCTGGCCCTG 
GGGAGTGACT ATACATTCTC TCAGATATAC CAGTGGGATA AAGAGAAGCA GCTATTCAAA 
AAGTTTAAGG AGATTTACGT GCAGGCGCCT CGTTCATTCA CAGCTGTCTC CACCGACAGG 
AGAGATTTCT TTTTTGCATC CAGTTTCAAA GGGAAAACAA AGATTTTTGA ACATATAATT 
GTTGACTTAA GTTTGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

LGI2 ( XM_011513850.2 ) cDNA ORF clone, Homo sapiens(human) -> XP_011512152.1 Homo sapiens leucine rich repeat LGI family member 2 (LGI2), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OHu69152
Clone ID Related Accession (Same CDS sequence)	XM_011513850.2
Accession Version	XM_011513850.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 996bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-05
Organism	Homo sapiens(human)
Product	leucine-rich repeat LGI family member 2 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000004.12) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 6, 2016 this sequence version replaced XM_011513850.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGCGCTGC GGAGAGGCGG CTGCGGAGCG CTCGGGCTGC TGCTGCTGCT GCTGGGCGCC 
GCGTGCCTGA TACCGCGGAG CGCGCAGGTG AGGCGGCTGG CGCGCTGCCC CGCCACTTGC 
AGCTGTACCA AGGAGTCTAT CATCTGCGTG GGCTCTTCCT GGGTGCCCAG GATCGTGCCG 
GGCGACATCA GCTCCCTGAG CCTGGTAAAT GGGACGTTTT CAGAAATCAA GGACCGAATG 
TTTTCCCATC TGCCTTCTCT GCAGCTGCTA TTGCTGAATT CTAACTCATT CACGATCATC 
CGGGATGATG CTTTTGCTGG ACTTTTTCAT CTTGAATACC TGTTCATTGA AGGGAACAAA 
ATAGAAACCA TTTCAAGAAA TGCCTTTCGT GGCCTCCGTG ACCTGACTCA CCTTTCTTTG 
GCCAATAACC ACATAAAAGC ACTACCAAGG GATGTCTTCA GTGATTTAGA CTCTCTGATT 
GAACTAGATT TGAGGGGTAA TAAATTTGAA TGTGACTGCA AAGCCAAGTG GCTATACCTG 
TGGTTGAAGA TGACAAATTC CACCGTTTCT GATGTGCTGT GTATTGGTCC ACCAGAGTAT 
CAGGAAAAGA AGCTAAATGA CGTGACCAGC TTTGACTATG AATGCACAAC TACAGATTTT 
GTTGTTCATC AGACTTTACC CTACCAGTCG GTTTCAGTGG ATACGTTCAA CTCCAAGAAC 
GATGTGTACG TGGCCATCGC GCAGCCCAGC ATGGAGAACT GCATGGTGCT GGAGTGGGAC 
CACATTGAAA TGAATTTCCG GAGCTATGAC AACATTACAG GCCTGGTGAC CATGTTGCCA 
AAGGGATGGC TCCAGCTGTC CATGTGCACC AGGGGAGAGA GAGAAACCCA TGGTCATGTT 
CACCCTGAGG TTCACTTCCC CTTGTTCTCT CTACGTCTCA TCTTGGCTTT CTCAATTTTG 
GTTTATTTTG TTCGCCTTTT GATTTCTGCA GGCTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_011512152.1
CDS	2..997
Translation	MALRRGGCGALGLLLLLLGAACLIPRSAQVRRLARCPATCSCTKESIICVGSSWVPRIVPGDISSLSLVNGTFSEIKDRMFSHLPSLQLLLLNSNSFTIIRDDAFAGLFHLEYLFIEGNKIETISRNAFRGLRDLTHLSLANNHIKALPRDVFSDLDSLIELDLRGNKFECDCKAKWLYLWLKMTNSTVSDVLCIGPPEYQEKKLNDVTSFDYECTTTDFVVHQTLPYQSVSVDTFNSKNDVYVAIAQPSMENCMVLEWDHIEMNFRSYDNITGLVTMLPKGWLQLSMCTRGERETHGHVHPEVHFPLFSLRLILAFSILVYFVRLLISAG

Target ORF information:

RefSeq Version	XM_011513850.2
Organism	Homo sapiens(human)
Definition	Homo sapiens leucine rich repeat LGI family member 2 (LGI2), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_011513850.2

ORF Insert Sequence:

ATGGCGCTGC GGAGAGGCGG CTGCGGAGCG CTCGGGCTGC TGCTGCTGCT GCTGGGCGCC 
GCGTGCCTGA TACCGCGGAG CGCGCAGGTG AGGCGGCTGG CGCGCTGCCC CGCCACTTGC 
AGCTGTACCA AGGAGTCTAT CATCTGCGTG GGCTCTTCCT GGGTGCCCAG GATCGTGCCG 
GGCGACATCA GCTCCCTGAG CCTGGTAAAT GGGACGTTTT CAGAAATCAA GGACCGAATG 
TTTTCCCATC TGCCTTCTCT GCAGCTGCTA TTGCTGAATT CTAACTCATT CACGATCATC 
CGGGATGATG CTTTTGCTGG ACTTTTTCAT CTTGAATACC TGTTCATTGA AGGGAACAAA 
ATAGAAACCA TTTCAAGAAA TGCCTTTCGT GGCCTCCGTG ACCTGACTCA CCTTTCTTTG 
GCCAATAACC ACATAAAAGC ACTACCAAGG GATGTCTTCA GTGATTTAGA CTCTCTGATT 
GAACTAGATT TGAGGGGTAA TAAATTTGAA TGTGACTGCA AAGCCAAGTG GCTATACCTG 
TGGTTGAAGA TGACAAATTC CACCGTTTCT GATGTGCTGT GTATTGGTCC ACCAGAGTAT 
CAGGAAAAGA AGCTAAATGA CGTGACCAGC TTTGACTATG AATGCACAAC TACAGATTTT 
GTTGTTCATC AGACTTTACC CTACCAGTCG GTTTCAGTGG ATACGTTCAA CTCCAAGAAC 
GATGTGTACG TGGCCATCGC GCAGCCCAGC ATGGAGAACT GCATGGTGCT GGAGTGGGAC 
CACATTGAAA TGAATTTCCG GAGCTATGAC AACATTACAG GCCTGGTGAC CATGTTGCCA 
AAGGGATGGC TCCAGCTGTC CATGTGCACC AGGGGAGAGA GAGAAACCCA TGGTCATGTT 
CACCCTGAGG TTCACTTCCC CTTGTTCTCT CTACGTCTCA TCTTGGCTTT CTCAATTTTG 
GTTTATTTTG TTCGCCTTTT GATTTCTGCA GGCTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

LGI2 ( XM_017008356.1 ) cDNA ORF clone, Homo sapiens(human) -> XP_016863845.1 Homo sapiens leucine rich repeat LGI family member 2 (LGI2), transcript variant X2, mRNA.

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CloneID	OHu95271
Clone ID Related Accession (Same CDS sequence)	XM_017008356.1
Accession Version	XM_017008356.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 864bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-05
Organism	Homo sapiens(human)
Product	leucine-rich repeat LGI family member 2 isoform X2
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000004.12) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGCGCTGC GGAGAGGCGG CTGCGGAGCG CTCGGGCTGC TGCTGCTGCT GCTGGGCGCC 
GCGTGCCTGA TACCGCGGAG CGCGCAGGTG AGGCGGCTGG CGCGCTGCCC CGCCACTTGC 
AGCTGTACCA AGGAGTCTAT CATCTGCGTG GGCTCTTCCT GGGTGCCCAG GATCGTGCCG 
GGCGACATCA GCTCCCTGAG CCTGGTAAAT GGGACGTTTT CAGAAATCAA GGACCGAATG 
TTTTCCCATC TGCCTTCTCT GCAGCTGCTA TTGCTGAATT CTAACTCATT CACGATCATC 
CGGGATGATG CTTTTGCTGG ACTTTTTCAT CTTGAATACC TGTTCATTGA AGGGAACAAA 
ATAGAAACCA TTTCAAGAAA TGCCTTTCGT GGCCTCCGTG ACCTGACTCA CCTTTCTTTG 
GCCAATAACC ACATAAAAGC ACTACCAAGG GATGTCTTCA GTGATTTAGA CTCTCTGATT 
GAACTAGATT TGAGGGGTAA TAAATTTGAA TGTGACTGCA AAGCCAAGTG GCTATACCTG 
TGGTTGAAGA TGACAAATTC CACCGTTTCT GATGTGCTGT GTATTGGTCC ACCAGAGTAT 
CAGGAAAAGA AGCTAAATGA CGTGACCAGC TTTGACTATG AATGCACAAC TACAGATTTT 
GTTGTTCATC AGACTTTACC CTACCAGTCG GTTTCAGTGG ATACGTTCAA CTCCAAGAAC 
GATGTGTACG TGGCCATCGC GCAGCCCAGC ATGGAGAACT GCATGGTGCT GGAGTGGGAC 
CACATTGAAA TGAATTTCCG GAGCTATGAC AACATTACAG TGGAAGATGA TGAACATGGT 
ACCACCTTGG AATCTGCAGC TTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_016863845.1
CDS	2..865
Translation	MALRRGGCGALGLLLLLLGAACLIPRSAQVRRLARCPATCSCTKESIICVGSSWVPRIVPGDISSLSLVNGTFSEIKDRMFSHLPSLQLLLLNSNSFTIIRDDAFAGLFHLEYLFIEGNKIETISRNAFRGLRDLTHLSLANNHIKALPRDVFSDLDSLIELDLRGNKFECDCKAKWLYLWLKMTNSTVSDVLCIGPPEYQEKKLNDVTSFDYECTTTDFVVHQTLPYQSVSVDTFNSKNDVYVAIAQPSMENCMVLEWDHIEMNFRSYDNITVEDDEHGTTLESAA

Target ORF information:

RefSeq Version	XM_017008356.1
Organism	Homo sapiens(human)
Definition	Homo sapiens leucine rich repeat LGI family member 2 (LGI2), transcript variant X2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_017008356.1

ORF Insert Sequence:

ATGGCGCTGC GGAGAGGCGG CTGCGGAGCG CTCGGGCTGC TGCTGCTGCT GCTGGGCGCC 
GCGTGCCTGA TACCGCGGAG CGCGCAGGTG AGGCGGCTGG CGCGCTGCCC CGCCACTTGC 
AGCTGTACCA AGGAGTCTAT CATCTGCGTG GGCTCTTCCT GGGTGCCCAG GATCGTGCCG 
GGCGACATCA GCTCCCTGAG CCTGGTAAAT GGGACGTTTT CAGAAATCAA GGACCGAATG 
TTTTCCCATC TGCCTTCTCT GCAGCTGCTA TTGCTGAATT CTAACTCATT CACGATCATC 
CGGGATGATG CTTTTGCTGG ACTTTTTCAT CTTGAATACC TGTTCATTGA AGGGAACAAA 
ATAGAAACCA TTTCAAGAAA TGCCTTTCGT GGCCTCCGTG ACCTGACTCA CCTTTCTTTG 
GCCAATAACC ACATAAAAGC ACTACCAAGG GATGTCTTCA GTGATTTAGA CTCTCTGATT 
GAACTAGATT TGAGGGGTAA TAAATTTGAA TGTGACTGCA AAGCCAAGTG GCTATACCTG 
TGGTTGAAGA TGACAAATTC CACCGTTTCT GATGTGCTGT GTATTGGTCC ACCAGAGTAT 
CAGGAAAAGA AGCTAAATGA CGTGACCAGC TTTGACTATG AATGCACAAC TACAGATTTT 
GTTGTTCATC AGACTTTACC CTACCAGTCG GTTTCAGTGG ATACGTTCAA CTCCAAGAAC 
GATGTGTACG TGGCCATCGC GCAGCCCAGC ATGGAGAACT GCATGGTGCT GGAGTGGGAC 
CACATTGAAA TGAATTTCCG GAGCTATGAC AACATTACAG TGGAAGATGA TGAACATGGT 
ACCACCTTGG AATCTGCAGC TTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Similarity of molecular phenotype between known epilepsy gene LGI1 and disease candidate gene LGI2.
BMC biochemistry1139(2010 Sep)
Limviphuvadh V,Chua LL,Rahim RA,Eisenhaber F,Maurer-Stroh S,Adhikari S

Is LGI2 the candidate gene for partial epilepsy with pericentral spikes?
Journal of bioinformatics and computational biology8(1)117-27(2010 Feb)
Limviphuvadh V,Chua LL,Eisenhaber F,Adhikari S,Maurer-Stroh S

Using gene-history and expression analyses to assess the involvement of LGI genes in human disorders.
Molecular biology and evolution22(11)2209-16(2005 Nov)
Gu W,Gibert Y,Wirth T,Elischer A,Bloch W,Meyer A,Steinlein OK,Begemann G

A two-dimensional electrophoresis reference map of human ovary.
Journal of molecular medicine (Berlin, Germany)83(10)812-21(2005 Oct)
Wang L,Zhu YF,Guo XJ,Huo R,Ma X,Lin M,Zhou ZM,Sha JH

The novel EPTP repeat defines a superfamily of proteins implicated in epileptic disorders.
Trends in biochemical sciences27(9)441-4(2002 Sep)
Staub E,P?rez-Tur J,Siebert R,Nobile C,Moschonas NK,Deloukas P,Hinzmann B

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LGI2 cDNA ORF clone, Homo sapiens(human)

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Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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