Gene Symbol | OGFOD1 |
Entrez Gene ID | 55239 |
Full Name | 2-oxoglutarate and iron dependent oxygenase domain containing 1 |
Synonyms | TPA1 |
General protein information |
|
Gene Type | protein-coding |
Organism | Homo sapiens(human) |
Genome | |
Disorder MIM: |
ORF » Species Summary » Homo sapiens » OGFOD1 cDNA ORF clone
Gene Symbol | OGFOD1 |
Entrez Gene ID | 55239 |
Full Name | 2-oxoglutarate and iron dependent oxygenase domain containing 1 |
Synonyms | TPA1 |
General protein information |
|
Gene Type | protein-coding |
Organism | Homo sapiens(human) |
Genome | |
Disorder MIM: |
mRNA | Protein | Name |
---|---|---|
NM_018233.3 | NP_060703.3 | prolyl 3-hydroxylase OGFOD1 isoform 1 |
NM_001324363.1 | NP_001311292.1 | prolyl 3-hydroxylase OGFOD1 isoform 6 |
NM_001324363.2 | NP_001311292.1 | prolyl 3-hydroxylase OGFOD1 isoform 6 |
NM_001324360.2 | NP_001311289.1 | prolyl 3-hydroxylase OGFOD1 isoform 4 |
NM_001324358.1 | NP_001311287.1 | prolyl 3-hydroxylase OGFOD1 isoform 3 |
NM_001324362.1 | NP_001311291.1 | prolyl 3-hydroxylase OGFOD1 isoform 5 |
NM_001324359.1 | NP_001311288.1 | prolyl 3-hydroxylase OGFOD1 isoform 4 |
NM_001324361.1 | NP_001311290.1 | prolyl 3-hydroxylase OGFOD1 isoform 3 |
NM_018233.4 | NP_060703.3 | prolyl 3-hydroxylase OGFOD1 isoform 1 |
NM_001324357.1 | NP_001311286.1 | prolyl 3-hydroxylase OGFOD1 isoform 2 |
NM_001324360.1 | NP_001311289.1 | prolyl 3-hydroxylase OGFOD1 isoform 4 |
NM_001324357.2 | NP_001311286.1 | prolyl 3-hydroxylase OGFOD1 isoform 2 |
Homo sapiens (human) | OGFOD1 | NP_060703.3 |
Canis lupus familiaris (dog) | OGFOD1 | XP_535297.2 |
Gallus gallus (chicken) | OGFOD1 | XP_414062.4 |
Xenopus tropicalis (tropical clawed frog) | ogfod1 | NP_001016322.1 |
Bos taurus (cattle) | OGFOD1 | NP_001160085.1 |
Rattus norvegicus (Norway rat) | Ogfod1 | NP_001100881.1 |
LOC700219 | XP_002802535.1 | |
Danio rerio (zebrafish) | ogfod1 | NP_955983.1 |
Pan troglodytes (chimpanzee) | OGFOD1 | XP_001135958.1 |
Caenorhabditis elegans (roundworm) | C17G10.1 | NP_495088.1 |
Mus musculus (house mouse) | Ogfod1 | NP_808435.3 |
OGFOD1 is required for breast cancer cell proliferation and is associated with poor prognosis in breast cancer.
Kim JH, Lee SM, Lee JH, Chun S, Kang BH, Kwak S, Roe JS, Kim TW, Kim H, Kim WH, Cho EJ, Youn HD
Oncotarget6(23)19528-41(2015 Aug)
Hydroxylation of the eukaryotic ribosomal decoding center affects translational accuracy.
Loenarz C, Sekirnik R, Thalhammer A, Ge W, Spivakovsky E, Mackeen MM, McDonough MA, Cockman ME, Kessler BM, Ratcliffe PJ, Wolf A, Schofield CJ
Proceedings of the National Academy of Sciences of the United States of America111(11)4019-24(2014 Mar)
OGFOD1 catalyzes prolyl hydroxylation of RPS23 and is involved in translation control and stress granule formation.
Singleton RS, Liu-Yi P, Formenti F, Ge W, Sekirnik R, Fischer R, Adam J, Pollard PJ, Wolf A, Thalhammer A, Loenarz C, Flashman E, Yamamoto A, Coleman ML, Kessler BM, Wappner P, Schofield CJ, Ratcliffe PJ, Cockman ME
Proceedings of the National Academy of Sciences of the United States of America111(11)4031-6(2014 Mar)
OGFOD1, a member of the 2-oxoglutarate and iron dependent dioxygenase family, functions in ischemic signaling.
Saito K, Adachi N, Koyama H, Matsushita M
FEBS letters584(15)3340-7(2010 Aug)
OGFOD1, a novel modulator of eukaryotic translation initiation factor 2alpha phosphorylation and the cellular response to stress.
Wehner KA, Sch?tz S, Sarnow P
Molecular and cellular biology30(8)2006-16(2010 Apr)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
Propose that OGFOD1 is required for breast cancer cell proliferation and is associated with poor prognosis in breast cancer.
Title: OGFOD1 is required for breast cancer cell proliferation and is associated with poor prognosis in breast cancer.
OGFOD1 catalyzes prolyl hydroxylation of RPS23 and is involved in translation control and stress granule formation.
Title: OGFOD1 catalyzes prolyl hydroxylation of RPS23 and is involved in translation control and stress granule formation.
OGFOD1 plays an important role in ischemic cell survival and an OGFOD1 iron binding residue is required for ATPAF1 gene expression.
Title: OGFOD1, a member of the 2-oxoglutarate and iron dependent dioxygenase family, functions in ischemic signaling.
Data suggest that OGFOD1 plays important proapoptotic roles in the regulation of translation and HRI-mediated phosphorylation of eIF2alpha in cells subjected to arsenite-induced stress.
Title: OGFOD1, a novel modulator of eukaryotic translation initiation factor 2alpha phosphorylation and the cellular response to stress.
The following OGFOD1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the OGFOD1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
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CloneID | OHu28486 | |
Clone ID Related Accession (Same CDS sequence) | NM_018233.3 , NM_018233.4 | |
Accession Version | NM_018233.3 | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1629bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2018-06-22 | |
Organism | Homo sapiens(human) | |
Product | prolyl 3-hydroxylase OGFOD1 isoform 1 | |
Comment | Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AL711389.1, BC032919.1 and AC092140.4. On or before May 4, 2006 this sequence version replaced NM_001031707.1, NM_018233.2. ##Evidence-Data-START## Transcript exon combination :: SRR1803617.79858.1, SRR1803614.270601.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end. |
1 | ATGAATGGGA AGCGGCCAGC GGAGCCCGGC CCAGCCCGGG TGGGAAAAAA GGGAAAGAAG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_060703.3 |
CDS | 102..1730 |
Translation |
Target ORF information:
Target ORF information:
|
NM_018233.3 |
1 | ATGAATGGGA AGCGGCCAGC GGAGCCCGGC CCAGCCCGGG TGGGAAAAAA GGGAAAGAAG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OHu28486 | |
Clone ID Related Accession (Same CDS sequence) | NM_018233.3 , NM_018233.4 | |
Accession Version | NM_018233.4 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1629bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2020-01-01 | |
Organism | Homo sapiens(human) | |
Product | prolyl 3-hydroxylase OGFOD1 isoform 1 | |
Comment | Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from BC032919.1 and AC092140.4. On May 17, 2019 this sequence version replaced NM_018233.3. ##Evidence-Data-START## Transcript exon combination :: SRR1660809.200390.1, SRR1803617.63173.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000566157.6/ ENSP00000457258.1 RefSeq Select criteria :: based on conservation, expression, longest protein ##RefSeq-Attributes-END## COMPLETENESS: complete on the 3' end. |
1 | ATGAATGGGA AGCGGCCAGC GGAGCCCGGC CCAGCCCGGG TGGGAAAAAA GGGAAAGAAG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_060703.3 |
CDS | 60..1688 |
Translation |
Target ORF information:
Target ORF information:
|
NM_018233.4 |
1 | ATGAATGGGA AGCGGCCAGC GGAGCCCGGC CCAGCCCGGG TGGGAAAAAA GGGAAAGAAG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OHu100571 | |
Clone ID Related Accession (Same CDS sequence) | NM_001324358.1 , NM_001324361.1 | |
Accession Version | NM_001324358.1 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1464bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2018-06-30 | |
Organism | Homo sapiens(human) | |
Product | prolyl 3-hydroxylase OGFOD1 isoform 3 | |
Comment | Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AC092140.4. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. ##Evidence-Data-START## Transcript exon combination :: SRR1803612.159241.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1968968, SAMEA2145893 [ECO:0000348] ##Evidence-Data-END## |
1 | ATGGACATGG ACCCTTTTCT TCACTGTGTG ATCCCAAACT TCATCCAAAG CCAAGACTTC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_001311287.1 |
CDS | 478..1941 |
Translation |
Target ORF information:
Target ORF information:
|
NM_001324358.1 |
1 | ATGGACATGG ACCCTTTTCT TCACTGTGTG ATCCCAAACT TCATCCAAAG CCAAGACTTC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OHu100571 | |
Clone ID Related Accession (Same CDS sequence) | NM_001324358.1 , NM_001324361.1 | |
Accession Version | NM_001324361.1 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1464bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2018-06-30 | |
Organism | Homo sapiens(human) | |
Product | prolyl 3-hydroxylase OGFOD1 isoform 3 | |
Comment | Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AC092140.4. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. ##Evidence-Data-START## Transcript exon combination :: SRR1660803.6981.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1968540, SAMEA1968968 [ECO:0000348] ##Evidence-Data-END## |
1 | ATGGACATGG ACCCTTTTCT TCACTGTGTG ATCCCAAACT TCATCCAAAG CCAAGACTTC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_001311290.1 |
CDS | 56..1519 |
Translation |
Target ORF information:
Target ORF information:
|
NM_001324361.1 |
1 | ATGGACATGG ACCCTTTTCT TCACTGTGTG ATCCCAAACT TCATCCAAAG CCAAGACTTC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OHu100581 | |
Clone ID Related Accession (Same CDS sequence) | NM_001324362.1 | |
Accession Version | NM_001324362.1 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1209bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2018-06-30 | |
Organism | Homo sapiens(human) | |
Product | prolyl 3-hydroxylase OGFOD1 isoform 5 | |
Comment | Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AC092140.4. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. ##Evidence-Data-START## Transcript exon combination :: AK001688.1, SRR1163658.189376.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2156099, SAMEA2162328 [ECO:0000348] ##Evidence-Data-END## |
1 | ATGTCCTGTG CTAAATATGA ATTCACTGAT GCCCTGCTGT GCCATGATGA TGAGCTGGAA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_001311291.1 |
CDS | 283..1491 |
Translation |
Target ORF information:
Target ORF information:
|
NM_001324362.1 |
1 | ATGTCCTGTG CTAAATATGA ATTCACTGAT GCCCTGCTGT GCCATGATGA TGAGCTGGAA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OHu100649 | |
Clone ID Related Accession (Same CDS sequence) | NM_001324360.2 , NM_001324359.1 , NM_001324360.1 | |
Accession Version | NM_001324360.2 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1338bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-05-30 | |
Organism | Homo sapiens(human) | |
Product | prolyl 3-hydroxylase OGFOD1 isoform 4 | |
Comment | Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AC092140.4. On May 31, 2019 this sequence version replaced NM_001324360.1. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. ##Evidence-Data-START## Transcript exon combination :: SRR1803614.152281.1, SRR1803616.88876.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1968189, SAMEA2145240 [ECO:0000348] ##Evidence-Data-END## |
1 | ATGATCAAGT CTGATGATTT GAAGAAGAGA AGAGAGCCTC ACATCTCCAC TTTAAGGAAA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_001311289.1 |
CDS | 386..1723 |
Translation |
Target ORF information:
Target ORF information:
|
NM_001324360.2 |
1 | ATGATCAAGT CTGATGATTT GAAGAAGAGA AGAGAGCCTC ACATCTCCAC TTTAAGGAAA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OHu100649 | |
Clone ID Related Accession (Same CDS sequence) | NM_001324360.2 , NM_001324359.1 , NM_001324360.1 | |
Accession Version | NM_001324359.1 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1338bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2018-06-30 | |
Organism | Homo sapiens(human) | |
Product | prolyl 3-hydroxylase OGFOD1 isoform 4 | |
Comment | Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AC092140.4. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. ##Evidence-Data-START## Transcript exon combination :: SRR1803613.127636.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2148874, SAMEA2149398 [ECO:0000348] ##Evidence-Data-END## |
1 | ATGATCAAGT CTGATGATTT GAAGAAGAGA AGAGAGCCTC ACATCTCCAC TTTAAGGAAA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_001311288.1 |
CDS | 217..1554 |
Translation |
Target ORF information:
Target ORF information:
|
NM_001324359.1 |
1 | ATGATCAAGT CTGATGATTT GAAGAAGAGA AGAGAGCCTC ACATCTCCAC TTTAAGGAAA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OHu100649 | |
Clone ID Related Accession (Same CDS sequence) | NM_001324360.2 , NM_001324359.1 , NM_001324360.1 | |
Accession Version | NM_001324360.1 | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1338bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2018-06-29 | |
Organism | Homo sapiens(human) | |
Product | prolyl 3-hydroxylase OGFOD1 isoform 4 | |
Comment | Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AC092140.4. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. ##Evidence-Data-START## Transcript exon combination :: SRR1803613.176067.1, SRR1803614.152281.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1968189, SAMEA2145240 [ECO:0000348] ##Evidence-Data-END## |
1 | ATGATCAAGT CTGATGATTT GAAGAAGAGA AGAGAGCCTC ACATCTCCAC TTTAAGGAAA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_001311289.1 |
CDS | 460..1797 |
Translation |
Target ORF information:
Target ORF information:
|
NM_001324360.1 |
1 | ATGATCAAGT CTGATGATTT GAAGAAGAGA AGAGAGCCTC ACATCTCCAC TTTAAGGAAA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OHu100623 | |
Clone ID Related Accession (Same CDS sequence) | NM_001324363.1 , NM_001324363.2 | |
Accession Version | NM_001324363.1 | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1515bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2018-06-30 | |
Organism | Homo sapiens(human) | |
Product | prolyl 3-hydroxylase OGFOD1 isoform 6 | |
Comment | Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AC092140.4. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. ##Evidence-Data-START## Transcript exon combination :: SRR1163658.540948.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2146236, SAMEA2147596 [ECO:0000348] ##Evidence-Data-END## |
1 | ATGAATGGGA AGCGGCCAGC GGAGCCCGGC CCAGCCCGGG TGGGAAAAAA GGGAAAGAAG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_001311292.1 |
CDS | 134..1648 |
Translation |
Target ORF information:
Target ORF information:
|
NM_001324363.1 |
1 | ATGAATGGGA AGCGGCCAGC GGAGCCCGGC CCAGCCCGGG TGGGAAAAAA GGGAAAGAAG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OHu100623 | |
Clone ID Related Accession (Same CDS sequence) | NM_001324363.1 , NM_001324363.2 | |
Accession Version | NM_001324363.2 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1515bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-05-30 | |
Organism | Homo sapiens(human) | |
Product | prolyl 3-hydroxylase OGFOD1 isoform 6 | |
Comment | Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AC092140.4. On May 31, 2019 this sequence version replaced NM_001324363.1. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. ##Evidence-Data-START## Transcript exon combination :: SRR3476690.192188.1, SRR1163658.540948.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2146236, SAMEA2147596 [ECO:0000348] ##Evidence-Data-END## |
1 | ATGAATGGGA AGCGGCCAGC GGAGCCCGGC CCAGCCCGGG TGGGAAAAAA GGGAAAGAAG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_001311292.1 |
CDS | 60..1574 |
Translation |
Target ORF information:
Target ORF information:
|
NM_001324363.2 |
1 | ATGAATGGGA AGCGGCCAGC GGAGCCCGGC CCAGCCCGGG TGGGAAAAAA GGGAAAGAAG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OHu100690 | |
Clone ID Related Accession (Same CDS sequence) | NM_001324357.1 , NM_001324357.2 | |
Accession Version | NM_001324357.1 | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1626bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2018-06-30 | |
Organism | Homo sapiens(human) | |
Product | prolyl 3-hydroxylase OGFOD1 isoform 2 | |
Comment | Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AC092140.4. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. ##Evidence-Data-START## Transcript exon combination :: SRR1803615.89093.1, SRR1803616.168678.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1968540, SAMEA1970526 [ECO:0000348] ##Evidence-Data-END## |
1 | ATGAATGGGA AGCGGCCAGC GGAGCCCGGC CCAGCCCGGG TGGGAAAAAA GGGAAAGAAG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_001311286.1 |
CDS | 134..1759 |
Translation |
Target ORF information:
Target ORF information:
|
NM_001324357.1 |
1 | ATGAATGGGA AGCGGCCAGC GGAGCCCGGC CCAGCCCGGG TGGGAAAAAA GGGAAAGAAG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OHu100690 | |
Clone ID Related Accession (Same CDS sequence) | NM_001324357.1 , NM_001324357.2 | |
Accession Version | NM_001324357.2 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1626bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-12-31 | |
Organism | Homo sapiens(human) | |
Product | prolyl 3-hydroxylase OGFOD1 isoform 2 | |
Comment | Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AC092140.4. On May 31, 2019 this sequence version replaced NM_001324357.1. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. ##Evidence-Data-START## Transcript exon combination :: SRR1803616.168678.1, SRR1803615.89093.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1968540, SAMEA1970526 [ECO:0000348] ##Evidence-Data-END## |
1 | ATGAATGGGA AGCGGCCAGC GGAGCCCGGC CCAGCCCGGG TGGGAAAAAA GGGAAAGAAG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_001311286.1 |
CDS | 60..1685 |
Translation |
Target ORF information:
Target ORF information:
|
NM_001324357.2 |
1 | ATGAATGGGA AGCGGCCAGC GGAGCCCGGC CCAGCCCGGG TGGGAAAAAA GGGAAAGAAG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
OGFOD1 is required for breast cancer cell proliferation and is associated with poor prognosis in breast cancer. |
Hydroxylation of the eukaryotic ribosomal decoding center affects translational accuracy. |
OGFOD1 catalyzes prolyl hydroxylation of RPS23 and is involved in translation control and stress granule formation. |
OGFOD1, a member of the 2-oxoglutarate and iron dependent dioxygenase family, functions in ischemic signaling. |
OGFOD1, a novel modulator of eukaryotic translation initiation factor 2alpha phosphorylation and the cellular response to stress. |