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HEG1 cDNA ORF clone, Homo sapiens(human)

Summary

Gene Symbol HEG1
Entrez Gene ID 57493
Full Name heart development protein with EGF like domains 1
Synonyms HEG,MST112,MSTP112
General protein information
Preferred Names

heart development protein with EGF like domains 1

Names

protein HEG homolog 1
HEG homolog 1
heart of glass
Gene Type protein-coding
Organism Homo sapiens(human)
Genome

3

3q21.2
Disorder MIM:

614182


Reference Sequences (RefSeq)

mRNA and Protein(s)

mRNA Protein Name
NM_020733.1 NP_065784.1 protein HEG homolog 1 precursor
XM_005247666.1 XP_005247723.1 protein HEG homolog 1 isoform X1
NM_020733.2 NP_065784.1 protein HEG homolog 1 precursor

Pathways from BioSystems


Homologies


Homo sapiens (human) HEG1 NP_065784.1
HEG1 XP_002802724.1
Bos taurus (cattle) HEG1 XP_002684860.1
Mus musculus (house mouse) Heg1 NP_780465.4
Rattus norvegicus (Norway rat) Heg1 XP_006248505.1
Pan troglodytes (chimpanzee) HEG1 XP_516708.4
Canis lupus familiaris (dog) HEG1 XP_005639641.1

Gene Ontology


Bibliography

Related articles in PubMed

HEG1 is a novel mucin-like membrane protein that serves as a diagnostic and therapeutic target for malignant mesothelioma.
Tsuji S, Washimi K, Kageyama T, Yamashita M, Yoshihara M, Matsuura R, Yokose T, Kameda Y, Hayashi H, Morohoshi T, Tsuura Y, Yusa T, Sato T, Togayachi A, Narimatsu H, Nagasaki T, Nakamoto K, Moriwaki Y, Misawa H, Hiroshima K, Miyagi Y, Imai K
Scientific reports745768(2017 Mar)

Heart of glass anchors Rasip1 at endothelial cell-cell junctions to support vascular integrity.
de Kreuk BJ, Gingras AR, Knight JD, Liu JJ, Gingras AC, Ginsberg MH
eLife5e11394(2016 Jan)

Cerebral cavernous malformations arise independent of the heart of glass receptor.
Zheng X, Riant F, Bergametti F, Myers CD, Tang AT, Kleaveland B, Pan W, Yang J, Tournier-Lasserve E, Kahn ML
Stroke45(5)1505-1509(2014 May)

The structure of the ternary complex of Krev interaction trapped 1 (KRIT1) bound to both the Rap1 GTPase and the heart of glass (HEG1) cytoplasmic tail.
Gingras AR, Puzon-McLaughlin W, Ginsberg MH
The Journal of biological chemistry288(33)23639-49(2013 Aug)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

These studies establish that the binding of HEG1 to Rasip1 mediates Rap1-dependent recruitment of Rasip1 to and stabilization of endothelial cell cell-cell junctions.
Title: Heart of glass anchors Rasip1 at endothelial cell-cell junctions to support vascular integrity.

Human patients with cerebral cavernous malformations who lack exonic mutations in krev interaction trapped protein (KRIT)1, cerebral cavernous malformation (CCM) protein 2, or programmed cell death (PDCD)10 protein do not have mutations in HEG.
Title: Cerebral cavernous malformations arise independent of the heart of glass receptor.

These data show that HEG1 can recruit the Rap1-KRIT complex to the plasma membrane.
Title: The structure of the ternary complex of Krev interaction trapped 1 (KRIT1) bound to both the Rap1 GTPase and the heart of glass (HEG1) cytoplasmic tail.

Clinical trial of gene-disease association and gene-environment interaction. (HuGE Navigator)
Title: Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score.

Identification of the zebrafish heart of glass (heg) gene. Description of HEG's role in the regulation of concentric heart growth in zebrafish.
Title: heart of glass regulates the concentric growth of the heart in zebrafish.

The following HEG1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the HEG1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID Accession No. Definition **Vector *Turnaround time Price (USD) Select
OHu03459 NM_020733.2
Latest version!		 Homo sapiens heart development protein with EGF like domains 1 (HEG1), mRNA. pcDNA3.1+/C-(K)DYK or customized vector TBD $923.30
$1319.00
OHu38076 XM_005247666.1
Latest version!		 Homo sapiens heart development protein with EGF like domains 1 (HEG1), transcript variant X1, mRNA. pcDNA3.1+/C-(K)DYK or customized vector TBD $727.30
$1039.00
View Old Accession Versions >>
OHu03459 NM_020733.1 Homo sapiens heart development protein with EGF like domains 1 (HEG1), mRNA. pcDNA3.1+/C-(K)DYK or customized vector TBD $923.30
$1319.00
Hide Old Accession Versions >>

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)


CloneID OHu03459
Clone ID Related Accession (Same CDS sequence) NM_020733.1 , NM_020733.2
Accession Version NM_020733.1 Documents for ORF clone product in default vector
Sequence Information ORF Nucleotide Sequence (Length: 4146bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ™ Seamless cloning technology
Insert Structure linear
Update Date 2017-12-26
Organism Homo sapiens(human)
Product protein HEG homolog 1 precursor
Comment Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from DR003209.1, AB033063.2, AC092983.13 and AC026342.34. On or before Jul 26, 2007 this sequence version replaced XM_087386.9, XM_001129251.1. ##Evidence-Data-START## RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end. 

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
1501
1561
1621
1681
1741
1801
1861
1921
1981
2041
2101
2161
2221
2281
2341
2401
2461
2521
2581
2641
2701
2761
2821
2881
2941
3001
3061
3121
3181
3241
3301
3361
3421
3481
3541
3601
3661
3721
3781
3841
3901
3961
4021
4081
4141
ATGGCCTCGC CGCGCGCCTC GCGGTGGCCG CCGCCGCTCC TGCTGCTGTT GCTGCCGCTG 
CTGCTGCTGC CGCCGGCGGC CCCCGGGACG CGGGACCCGC CGCCTTCCCC GGCTCGCCGC 
GCGCTGAGCC TGGCGCCCCT CGCGGGAGCG GGGCTGGAGC TGCAGCTGGA GCGCCGCCCG 
GAGCGCGAGC CGCCGCCCAC GCCGCCCCGG GAGCGCCGCG GGCCCGCGAC CCCCGGCCCC 
AGCTACAGGG CCCCTGAGCC AGGCGCCGCG ACACAGCGGG GACCCTCCGG CCGGGCCCCC 
AGAGGCGGGA GCGCGGATGC TGCCTGGAAA CATTGGCCAG AAAGTAACAC TGAGGCCCAT 
GTAGAAAACA TCACCTTCTA TCAGAATCAA GAGGACTTTT CAACAGTGTC CTCCAAAGAG 
GGCGTGATGG TTCAGACCTC TGGGAAGAGC CATGCTGCTT CGGATGCTCC AGAAAACCTC 
ACTCTACTCG CTGAAACAGC AGATGCTAGA GGAAGGAGCG GCTCTTCAAG TAGAACAAAC 
TTCACCATTT TGCCTGTTGG GTACTCACTG GAGATAGCAA CAGCTCTGAC TTCCCAGAGT 
GGCAACTTAG CCTCAGAAAG TCTTCACCTG CCATCCAGCA GTTCAGAGTT CGATGAAAGA 
ATTGCCGCTT TTCAAACAAA GAGTGGAACA GCCTCGGAGA TGGGAACAGA GAGGGCGATG 
GGGCTGTCAG AAGAATGGAC TGTGCACAGC CAAGAGGCCA CCACTTCGGC TTGGAGCCCG 
TCCTTTCTTC CTGCTTTGGA GATGGGAGAG CTGACCACGC CTTCTAGGAA GAGAAATTCC 
TCAGGACCAG ATCTCTCCTG GCTGCATTTC TACAGGACAG CAGCTTCCTC TCCTCTCTTA 
GACCTTTCCT CATCTTCTGA AAGTACAGAG AAGCTTAACA ACTCCACTGG CCTCCAGAGC 
TCCTCAGTCA GTCAAACAAA GACAATGCAT GTTGCCACCG TGTTCACTGA TGGTGGCCCG 
AGAACGCTGC GATCTTTGAC GGTCAGTCTG GGACCTGTGA GCAAGACAGA AGGCTTCCCC 
AAGGACTCCA GAATTGCCAC GACTTCATCC TCAGTCCTTC TTTCACCCTC TGCAGTGGAA 
TCGAGAAGAA ACAGTAGAGT AACTGGGAAT CCAGGGGATG AGGAATTCAT TGAACCATCC 
ACAGAAAATG AATTTGGACT TACGTCTTTG CGTTGGCAAA ATGATTCCCC AACCTTTGGA 
GAACATCAGC TTGCCAGCAG CTCTGAGGTG CAAAATGGAA GTCCCATGTC TCAGACTGAG 
ACTGTGTCTA GGTCAGTCGC ACCCATGAGA GGTGGAGAGA TCACTGCACA CTGGCTCTTG 
ACCAACAGCA CAACATCTGC AGATGTGACA GGAAGCTCTG CTTCATATCC TGAAGGTGTG 
AATGCTTCAG TGTTGACCCA GTTCTCAGAC TCTACTGTAC AGTCTGGAGG AAGTCACACA 
GCATTGGGAG ATAGGAGTTA TTCAGAGTCT TCATCTACAT CTTCCTCGGA AAGCTTGAAT 
TCATCAGCAC CACGTGGAGA ACGTTCGATC GCTGGGATTA GCTACGGTCA AGTGCGTGGC 
ACAGCTATTG AACAAAGGAC TTCCAGCGAC CACACAGACC ACACCTACCT GTCATCTACT 
TTCACCAAAG GAGAACGGGC GTTACTGTCC ATTACAGATA ACAGTTCATC CTCAGACATT 
GTGGAGAGCT CAACTTCTTA TATTAAAATC TCAAACTCTT CACATTCAGA GTATTCCTCC 
TTTTTTCATG CTCAGACTGA GAGAAGTAAC ATCTCATCCT ATGACGGGGA ATATGCTCAG 
CCTTCTACTG AGTCGCCAGT TCTGCATACA TCCAACCTTC CGTCCTACAC ACCCACCATT 
AATATGCCGA ACACTTCGGT TGTTCTGGAC ACTGATGCTG AGTTTGTTAG TGACTCCTCC 
TCCTCCTCTT CCTCCTCCTC CTCTTCTTCT TCTTCAGGGC CTCCTTTGCC TCTGCCCTCT 
GTGTCACAAT CCCACCATTT ATTTTCATCA ATTTTACCAT CAACCAGGGC CTCTGTGCAT 
CTACTAAAGT CTACCTCTGA TGCATCCACA CCATGGTCTT CCTCACCATC ACCTTTACCA 
GTATCCTTAA CGACATCTAC ATCTGCCCCA CTTTCTGTCT CACAAACAAC CTTGCCACAG 
TCATCTTCTA CCCCTGTCCT GCCCAGGGCA AGGGAGACTC CTGTGACTTC ATTTCAGACA 
TCAACAATGA CATCATTCAT GACAATGCTC CATAGTAGTC AAACTGCAGA CCTTAAGAGC 
CAGAGCACCC CACACCAAGA GAAAGTCATT ACAGAATCAA AGTCACCAAG CCTGGTGTCT 
CTGCCCACAG AGTCCACCAA AGCTGTAACA ACAAACTCTC CTTTGCCTCC ATCCTTAACA 
GAGTCCTCCA CAGAGCAAAC CCTTCCAGCC ACAAGCACCA ACTTAGCACA AATGTCTCCA 
ACTTTCACAA CTACCATTCT GAAGACCTCT CAGCCTCTTA TGACCACTCC TGGCACCCTG 
TCAAGCACAG CATCTCTGGT CACTGGCCCT ATAGCCGTAC AGACTACAGC TGGAAAACAG 
CTCTCGCTGA CCCATCCTGA AATACTAGTT CCTCAAATCT CAACAGAAGG TGGCATCAGC 
ACAGAAAGGA ACCGAGTGAT TGTGGATGCT ACCACTGGAT TGATCCCTTT GACCAGTGTA 
CCCACATCAG CAAAAGAAAT GACCACAAAG CTTGGCGTTA CAGCAGAGTA CAGCCCAGCT 
TCACGTTCCC TCGGAACATC TCCTTCTCCC CAAACCACAG TTGTTTCCAC GGCTGAAGAC 
TTGGCTCCCA AATCTGCCAC CTTTGCTGTT CAGAGCAGCA CACAGTCACC AACAACAGTG 
TCCTCTTCAG CCTCAGTCAA CAGCTGTGCT GTGAACCCTT GTCTTCACAA TGGCGAATGC 
GTCGCAGACA ACACCAGCCG TGGCTACCAC TGCAGGTGCC CGCCTTCCTG GCAAGGGGAT 
GATTGCAGTG TGGATGTGAA TGAGTGCCTG TCGAACCCCT GCCCATCCAC AGCCATGTGC 
AACAATACTC AGGGATCCTT TATCTGCAAA TGCCCGGTTG GGTACCAGTT GGAAAAAGGG 
ATATGCAATT TGGTTAGAAC CTTCGTGACA GAGTTTAAAT TAAAGAGAAC TTTTCTTAAT 
ACAACTGTGG AAAAACATTC AGACCTACAA GAAGTTGAAA ATGAGATCAC CAAAACGTTA 
AATATGTGTT TTTCAGCGTT ACCTAGTTAC ATCCGATCTA CAGTTCACGC CTCTAGGGAG 
TCCAACGCGG TGGTGATCTC ACTGCAAACA ACCTTTTCCC TGGCCTCCAA TGTGACGCTA 
TTTGACCTGG CTGATAGGAT GCAGAAATGT GTCAACTCCT GCAAGTCCTC TGCTGAGGTC 
TGCCAGCTCT TGGGATCTCA GAGGCGGATC TTTAGAGCGG GCAGCTTGTG CAAGCGGAAG 
AGTCCCGAAT GTGACAAAGA CACCTCCATC TGCACTGACC TGGACGGCGT TGCCCTGTGC 
CAGTGCAAGT CGGGATACTT TCAGTTCAAC AAGATGGACC ACTCCTGCCG AGCATGTGAA 
GATGGATATA GGCTTGAAAA TGAAACCTGC ATGAGTTGCC CATTTGGCCT TGGTGGTCTC 
AACTGTGGAA ACCCCTATCA GCTTATCACT GTGGTGATCG CAGCCGCGGG AGGTGGGCTC 
CTGCTCATCC TAGGCATCGC ACTGATTGTT ACCTGTTGCA GAAAGAATAA AAATGACATA 
AGCAAACTCA TCTTCAAAAG TGGAGATTTC CAAATGTCCC CGTATGCTGA ATACCCCAAA 
AATCCTCGCT CACAAGAATG GGGCCGAGAA GCTATTGAAA TGCATGAGAA TGGAAGTACC 
AAAAACCTCC TCCAGATGAC GGATGTGTAC TACTCGCCTA CAAGTGTAAG GAATCCAGAA 
CTTGAACGAA ACGGACTCTA CCCGGCCTAC ACTGGACTGC CAGGATCACG GCATTCTTGC 
ATTTTCCCCG GACAGTATAA CCCGTCTTTC ATCAGTGATG AAAGCAGAAG AAGAGACTAC 
TTTTAA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq NP_065784.1
CDS69..4214
Translation

Target ORF information:

RefSeq Version NM_020733.1
Organism Homo sapiens(human)
Definition Homo sapiens heart development protein with EGF like domains 1 (HEG1), mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
 NM_020733.1

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
1501
1561
1621
1681
1741
1801
1861
1921
1981
2041
2101
2161
2221
2281
2341
2401
2461
2521
2581
2641
2701
2761
2821
2881
2941
3001
3061
3121
3181
3241
3301
3361
3421
3481
3541
3601
3661
3721
3781
3841
3901
3961
4021
4081
4141
ATGGCCTCGC CGCGCGCCTC GCGGTGGCCG CCGCCGCTCC TGCTGCTGTT GCTGCCGCTG 
CTGCTGCTGC CGCCGGCGGC CCCCGGGACG CGGGACCCGC CGCCTTCCCC GGCTCGCCGC 
GCGCTGAGCC TGGCGCCCCT CGCGGGAGCG GGGCTGGAGC TGCAGCTGGA GCGCCGCCCG 
GAGCGCGAGC CGCCGCCCAC GCCGCCCCGG GAGCGCCGCG GGCCCGCGAC CCCCGGCCCC 
AGCTACAGGG CCCCTGAGCC AGGCGCCGCG ACACAGCGGG GACCCTCCGG CCGGGCCCCC 
AGAGGCGGGA GCGCGGATGC TGCCTGGAAA CATTGGCCAG AAAGTAACAC TGAGGCCCAT 
GTAGAAAACA TCACCTTCTA TCAGAATCAA GAGGACTTTT CAACAGTGTC CTCCAAAGAG 
GGCGTGATGG TTCAGACCTC TGGGAAGAGC CATGCTGCTT CGGATGCTCC AGAAAACCTC 
ACTCTACTCG CTGAAACAGC AGATGCTAGA GGAAGGAGCG GCTCTTCAAG TAGAACAAAC 
TTCACCATTT TGCCTGTTGG GTACTCACTG GAGATAGCAA CAGCTCTGAC TTCCCAGAGT 
GGCAACTTAG CCTCAGAAAG TCTTCACCTG CCATCCAGCA GTTCAGAGTT CGATGAAAGA 
ATTGCCGCTT TTCAAACAAA GAGTGGAACA GCCTCGGAGA TGGGAACAGA GAGGGCGATG 
GGGCTGTCAG AAGAATGGAC TGTGCACAGC CAAGAGGCCA CCACTTCGGC TTGGAGCCCG 
TCCTTTCTTC CTGCTTTGGA GATGGGAGAG CTGACCACGC CTTCTAGGAA GAGAAATTCC 
TCAGGACCAG ATCTCTCCTG GCTGCATTTC TACAGGACAG CAGCTTCCTC TCCTCTCTTA 
GACCTTTCCT CATCTTCTGA AAGTACAGAG AAGCTTAACA ACTCCACTGG CCTCCAGAGC 
TCCTCAGTCA GTCAAACAAA GACAATGCAT GTTGCCACCG TGTTCACTGA TGGTGGCCCG 
AGAACGCTGC GATCTTTGAC GGTCAGTCTG GGACCTGTGA GCAAGACAGA AGGCTTCCCC 
AAGGACTCCA GAATTGCCAC GACTTCATCC TCAGTCCTTC TTTCACCCTC TGCAGTGGAA 
TCGAGAAGAA ACAGTAGAGT AACTGGGAAT CCAGGGGATG AGGAATTCAT TGAACCATCC 
ACAGAAAATG AATTTGGACT TACGTCTTTG CGTTGGCAAA ATGATTCCCC AACCTTTGGA 
GAACATCAGC TTGCCAGCAG CTCTGAGGTG CAAAATGGAA GTCCCATGTC TCAGACTGAG 
ACTGTGTCTA GGTCAGTCGC ACCCATGAGA GGTGGAGAGA TCACTGCACA CTGGCTCTTG 
ACCAACAGCA CAACATCTGC AGATGTGACA GGAAGCTCTG CTTCATATCC TGAAGGTGTG 
AATGCTTCAG TGTTGACCCA GTTCTCAGAC TCTACTGTAC AGTCTGGAGG AAGTCACACA 
GCATTGGGAG ATAGGAGTTA TTCAGAGTCT TCATCTACAT CTTCCTCGGA AAGCTTGAAT 
TCATCAGCAC CACGTGGAGA ACGTTCGATC GCTGGGATTA GCTACGGTCA AGTGCGTGGC 
ACAGCTATTG AACAAAGGAC TTCCAGCGAC CACACAGACC ACACCTACCT GTCATCTACT 
TTCACCAAAG GAGAACGGGC GTTACTGTCC ATTACAGATA ACAGTTCATC CTCAGACATT 
GTGGAGAGCT CAACTTCTTA TATTAAAATC TCAAACTCTT CACATTCAGA GTATTCCTCC 
TTTTTTCATG CTCAGACTGA GAGAAGTAAC ATCTCATCCT ATGACGGGGA ATATGCTCAG 
CCTTCTACTG AGTCGCCAGT TCTGCATACA TCCAACCTTC CGTCCTACAC ACCCACCATT 
AATATGCCGA ACACTTCGGT TGTTCTGGAC ACTGATGCTG AGTTTGTTAG TGACTCCTCC 
TCCTCCTCTT CCTCCTCCTC CTCTTCTTCT TCTTCAGGGC CTCCTTTGCC TCTGCCCTCT 
GTGTCACAAT CCCACCATTT ATTTTCATCA ATTTTACCAT CAACCAGGGC CTCTGTGCAT 
CTACTAAAGT CTACCTCTGA TGCATCCACA CCATGGTCTT CCTCACCATC ACCTTTACCA 
GTATCCTTAA CGACATCTAC ATCTGCCCCA CTTTCTGTCT CACAAACAAC CTTGCCACAG 
TCATCTTCTA CCCCTGTCCT GCCCAGGGCA AGGGAGACTC CTGTGACTTC ATTTCAGACA 
TCAACAATGA CATCATTCAT GACAATGCTC CATAGTAGTC AAACTGCAGA CCTTAAGAGC 
CAGAGCACCC CACACCAAGA GAAAGTCATT ACAGAATCAA AGTCACCAAG CCTGGTGTCT 
CTGCCCACAG AGTCCACCAA AGCTGTAACA ACAAACTCTC CTTTGCCTCC ATCCTTAACA 
GAGTCCTCCA CAGAGCAAAC CCTTCCAGCC ACAAGCACCA ACTTAGCACA AATGTCTCCA 
ACTTTCACAA CTACCATTCT GAAGACCTCT CAGCCTCTTA TGACCACTCC TGGCACCCTG 
TCAAGCACAG CATCTCTGGT CACTGGCCCT ATAGCCGTAC AGACTACAGC TGGAAAACAG 
CTCTCGCTGA CCCATCCTGA AATACTAGTT CCTCAAATCT CAACAGAAGG TGGCATCAGC 
ACAGAAAGGA ACCGAGTGAT TGTGGATGCT ACCACTGGAT TGATCCCTTT GACCAGTGTA 
CCCACATCAG CAAAAGAAAT GACCACAAAG CTTGGCGTTA CAGCAGAGTA CAGCCCAGCT 
TCACGTTCCC TCGGAACATC TCCTTCTCCC CAAACCACAG TTGTTTCCAC GGCTGAAGAC 
TTGGCTCCCA AATCTGCCAC CTTTGCTGTT CAGAGCAGCA CACAGTCACC AACAACAGTG 
TCCTCTTCAG CCTCAGTCAA CAGCTGTGCT GTGAACCCTT GTCTTCACAA TGGCGAATGC 
GTCGCAGACA ACACCAGCCG TGGCTACCAC TGCAGGTGCC CGCCTTCCTG GCAAGGGGAT 
GATTGCAGTG TGGATGTGAA TGAGTGCCTG TCGAACCCCT GCCCATCCAC AGCCATGTGC 
AACAATACTC AGGGATCCTT TATCTGCAAA TGCCCGGTTG GGTACCAGTT GGAAAAAGGG 
ATATGCAATT TGGTTAGAAC CTTCGTGACA GAGTTTAAAT TAAAGAGAAC TTTTCTTAAT 
ACAACTGTGG AAAAACATTC AGACCTACAA GAAGTTGAAA ATGAGATCAC CAAAACGTTA 
AATATGTGTT TTTCAGCGTT ACCTAGTTAC ATCCGATCTA CAGTTCACGC CTCTAGGGAG 
TCCAACGCGG TGGTGATCTC ACTGCAAACA ACCTTTTCCC TGGCCTCCAA TGTGACGCTA 
TTTGACCTGG CTGATAGGAT GCAGAAATGT GTCAACTCCT GCAAGTCCTC TGCTGAGGTC 
TGCCAGCTCT TGGGATCTCA GAGGCGGATC TTTAGAGCGG GCAGCTTGTG CAAGCGGAAG 
AGTCCCGAAT GTGACAAAGA CACCTCCATC TGCACTGACC TGGACGGCGT TGCCCTGTGC 
CAGTGCAAGT CGGGATACTT TCAGTTCAAC AAGATGGACC ACTCCTGCCG AGCATGTGAA 
GATGGATATA GGCTTGAAAA TGAAACCTGC ATGAGTTGCC CATTTGGCCT TGGTGGTCTC 
AACTGTGGAA ACCCCTATCA GCTTATCACT GTGGTGATCG CAGCCGCGGG AGGTGGGCTC 
CTGCTCATCC TAGGCATCGC ACTGATTGTT ACCTGTTGCA GAAAGAATAA AAATGACATA 
AGCAAACTCA TCTTCAAAAG TGGAGATTTC CAAATGTCCC CGTATGCTGA ATACCCCAAA 
AATCCTCGCT CACAAGAATG GGGCCGAGAA GCTATTGAAA TGCATGAGAA TGGAAGTACC 
AAAAACCTCC TCCAGATGAC GGATGTGTAC TACTCGCCTA CAAGTGTAAG GAATCCAGAA 
CTTGAACGAA ACGGACTCTA CCCGGCCTAC ACTGGACTGC CAGGATCACG GCATTCTTGC 
ATTTTCCCCG GACAGTATAA CCCGTCTTTC ATCAGTGATG AAAGCAGAAG AAGAGACTAC 
TTTTAA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OHu03459
Clone ID Related Accession (Same CDS sequence) NM_020733.1 , NM_020733.2
Accession Version NM_020733.2 Latest version! Documents for ORF clone product in default vector
Sequence Information ORF Nucleotide Sequence (Length: 4146bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ™ Seamless cloning technology
Insert Structure linear
Update Date 2019-12-30
Organism Homo sapiens(human)
Product protein HEG homolog 1 precursor
Comment Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AC117488.11, DR003209.1, AB033063.2, AC092983.13 and AC026342.34. On Nov 23, 2018 this sequence version replaced NM_020733.1. ##Evidence-Data-START## RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000311127.9/ ENSP00000311502.3 RefSeq Select criteria :: based on conservation ##RefSeq-Attributes-END## COMPLETENESS: full length. 

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
1501
1561
1621
1681
1741
1801
1861
1921
1981
2041
2101
2161
2221
2281
2341
2401
2461
2521
2581
2641
2701
2761
2821
2881
2941
3001
3061
3121
3181
3241
3301
3361
3421
3481
3541
3601
3661
3721
3781
3841
3901
3961
4021
4081
4141
ATGGCCTCGC CGCGCGCCTC GCGGTGGCCG CCGCCGCTCC TGCTGCTGTT GCTGCCGCTG 
CTGCTGCTGC CGCCGGCGGC CCCCGGGACG CGGGACCCGC CGCCTTCCCC GGCTCGCCGC 
GCGCTGAGCC TGGCGCCCCT CGCGGGAGCG GGGCTGGAGC TGCAGCTGGA GCGCCGCCCG 
GAGCGCGAGC CGCCGCCCAC GCCGCCCCGG GAGCGCCGCG GGCCCGCGAC CCCCGGCCCC 
AGCTACAGGG CCCCTGAGCC AGGCGCCGCG ACACAGCGGG GACCCTCCGG CCGGGCCCCC 
AGAGGCGGGA GCGCGGATGC TGCCTGGAAA CATTGGCCAG AAAGTAACAC TGAGGCCCAT 
GTAGAAAACA TCACCTTCTA TCAGAATCAA GAGGACTTTT CAACAGTGTC CTCCAAAGAG 
GGCGTGATGG TTCAGACCTC TGGGAAGAGC CATGCTGCTT CGGATGCTCC AGAAAACCTC 
ACTCTACTCG CTGAAACAGC AGATGCTAGA GGAAGGAGCG GCTCTTCAAG TAGAACAAAC 
TTCACCATTT TGCCTGTTGG GTACTCACTG GAGATAGCAA CAGCTCTGAC TTCCCAGAGT 
GGCAACTTAG CCTCAGAAAG TCTTCACCTG CCATCCAGCA GTTCAGAGTT CGATGAAAGA 
ATTGCCGCTT TTCAAACAAA GAGTGGAACA GCCTCGGAGA TGGGAACAGA GAGGGCGATG 
GGGCTGTCAG AAGAATGGAC TGTGCACAGC CAAGAGGCCA CCACTTCGGC TTGGAGCCCG 
TCCTTTCTTC CTGCTTTGGA GATGGGAGAG CTGACCACGC CTTCTAGGAA GAGAAATTCC 
TCAGGACCAG ATCTCTCCTG GCTGCATTTC TACAGGACAG CAGCTTCCTC TCCTCTCTTA 
GACCTTTCCT CATCTTCTGA AAGTACAGAG AAGCTTAACA ACTCCACTGG CCTCCAGAGC 
TCCTCAGTCA GTCAAACAAA GACAATGCAT GTTGCCACCG TGTTCACTGA TGGTGGCCCG 
AGAACGCTGC GATCTTTGAC GGTCAGTCTG GGACCTGTGA GCAAGACAGA AGGCTTCCCC 
AAGGACTCCA GAATTGCCAC GACTTCATCC TCAGTCCTTC TTTCACCCTC TGCAGTGGAA 
TCGAGAAGAA ACAGTAGAGT AACTGGGAAT CCAGGGGATG AGGAATTCAT TGAACCATCC 
ACAGAAAATG AATTTGGACT TACGTCTTTG CGTTGGCAAA ATGATTCCCC AACCTTTGGA 
GAACATCAGC TTGCCAGCAG CTCTGAGGTG CAAAATGGAA GTCCCATGTC TCAGACTGAG 
ACTGTGTCTA GGTCAGTCGC ACCCATGAGA GGTGGAGAGA TCACTGCACA CTGGCTCTTG 
ACCAACAGCA CAACATCTGC AGATGTGACA GGAAGCTCTG CTTCATATCC TGAAGGTGTG 
AATGCTTCAG TGTTGACCCA GTTCTCAGAC TCTACTGTAC AGTCTGGAGG AAGTCACACA 
GCATTGGGAG ATAGGAGTTA TTCAGAGTCT TCATCTACAT CTTCCTCGGA AAGCTTGAAT 
TCATCAGCAC CACGTGGAGA ACGTTCGATC GCTGGGATTA GCTACGGTCA AGTGCGTGGC 
ACAGCTATTG AACAAAGGAC TTCCAGCGAC CACACAGACC ACACCTACCT GTCATCTACT 
TTCACCAAAG GAGAACGGGC GTTACTGTCC ATTACAGATA ACAGTTCATC CTCAGACATT 
GTGGAGAGCT CAACTTCTTA TATTAAAATC TCAAACTCTT CACATTCAGA GTATTCCTCC 
TTTTTTCATG CTCAGACTGA GAGAAGTAAC ATCTCATCCT ATGACGGGGA ATATGCTCAG 
CCTTCTACTG AGTCGCCAGT TCTGCATACA TCCAACCTTC CGTCCTACAC ACCCACCATT 
AATATGCCGA ACACTTCGGT TGTTCTGGAC ACTGATGCTG AGTTTGTTAG TGACTCCTCC 
TCCTCCTCTT CCTCCTCCTC CTCTTCTTCT TCTTCAGGGC CTCCTTTGCC TCTGCCCTCT 
GTGTCACAAT CCCACCATTT ATTTTCATCA ATTTTACCAT CAACCAGGGC CTCTGTGCAT 
CTACTAAAGT CTACCTCTGA TGCATCCACA CCATGGTCTT CCTCACCATC ACCTTTACCA 
GTATCCTTAA CGACATCTAC ATCTGCCCCA CTTTCTGTCT CACAAACAAC CTTGCCACAG 
TCATCTTCTA CCCCTGTCCT GCCCAGGGCA AGGGAGACTC CTGTGACTTC ATTTCAGACA 
TCAACAATGA CATCATTCAT GACAATGCTC CATAGTAGTC AAACTGCAGA CCTTAAGAGC 
CAGAGCACCC CACACCAAGA GAAAGTCATT ACAGAATCAA AGTCACCAAG CCTGGTGTCT 
CTGCCCACAG AGTCCACCAA AGCTGTAACA ACAAACTCTC CTTTGCCTCC ATCCTTAACA 
GAGTCCTCCA CAGAGCAAAC CCTTCCAGCC ACAAGCACCA ACTTAGCACA AATGTCTCCA 
ACTTTCACAA CTACCATTCT GAAGACCTCT CAGCCTCTTA TGACCACTCC TGGCACCCTG 
TCAAGCACAG CATCTCTGGT CACTGGCCCT ATAGCCGTAC AGACTACAGC TGGAAAACAG 
CTCTCGCTGA CCCATCCTGA AATACTAGTT CCTCAAATCT CAACAGAAGG TGGCATCAGC 
ACAGAAAGGA ACCGAGTGAT TGTGGATGCT ACCACTGGAT TGATCCCTTT GACCAGTGTA 
CCCACATCAG CAAAAGAAAT GACCACAAAG CTTGGCGTTA CAGCAGAGTA CAGCCCAGCT 
TCACGTTCCC TCGGAACATC TCCTTCTCCC CAAACCACAG TTGTTTCCAC GGCTGAAGAC 
TTGGCTCCCA AATCTGCCAC CTTTGCTGTT CAGAGCAGCA CACAGTCACC AACAACAGTG 
TCCTCTTCAG CCTCAGTCAA CAGCTGTGCT GTGAACCCTT GTCTTCACAA TGGCGAATGC 
GTCGCAGACA ACACCAGCCG TGGCTACCAC TGCAGGTGCC CGCCTTCCTG GCAAGGGGAT 
GATTGCAGTG TGGATGTGAA TGAGTGCCTG TCGAACCCCT GCCCATCCAC AGCCATGTGC 
AACAATACTC AGGGATCCTT TATCTGCAAA TGCCCGGTTG GGTACCAGTT GGAAAAAGGG 
ATATGCAATT TGGTTAGAAC CTTCGTGACA GAGTTTAAAT TAAAGAGAAC TTTTCTTAAT 
ACAACTGTGG AAAAACATTC AGACCTACAA GAAGTTGAAA ATGAGATCAC CAAAACGTTA 
AATATGTGTT TTTCAGCGTT ACCTAGTTAC ATCCGATCTA CAGTTCACGC CTCTAGGGAG 
TCCAACGCGG TGGTGATCTC ACTGCAAACA ACCTTTTCCC TGGCCTCCAA TGTGACGCTA 
TTTGACCTGG CTGATAGGAT GCAGAAATGT GTCAACTCCT GCAAGTCCTC TGCTGAGGTC 
TGCCAGCTCT TGGGATCTCA GAGGCGGATC TTTAGAGCGG GCAGCTTGTG CAAGCGGAAG 
AGTCCCGAAT GTGACAAAGA CACCTCCATC TGCACTGACC TGGACGGCGT TGCCCTGTGC 
CAGTGCAAGT CGGGATACTT TCAGTTCAAC AAGATGGACC ACTCCTGCCG AGCATGTGAA 
GATGGATATA GGCTTGAAAA TGAAACCTGC ATGAGTTGCC CATTTGGCCT TGGTGGTCTC 
AACTGTGGAA ACCCCTATCA GCTTATCACT GTGGTGATCG CAGCCGCGGG AGGTGGGCTC 
CTGCTCATCC TAGGCATCGC ACTGATTGTT ACCTGTTGCA GAAAGAATAA AAATGACATA 
AGCAAACTCA TCTTCAAAAG TGGAGATTTC CAAATGTCCC CGTATGCTGA ATACCCCAAA 
AATCCTCGCT CACAAGAATG GGGCCGAGAA GCTATTGAAA TGCATGAGAA TGGAAGTACC 
AAAAACCTCC TCCAGATGAC GGATGTGTAC TACTCGCCTA CAAGTGTAAG GAATCCAGAA 
CTTGAACGAA ACGGACTCTA CCCGGCCTAC ACTGGACTGC CAGGATCACG GCATTCTTGC 
ATTTTCCCCG GACAGTATAA CCCGTCTTTC ATCAGTGATG AAAGCAGAAG AAGAGACTAC 
TTTTAA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq NP_065784.1
CDS108..4253
Translation

Target ORF information:

RefSeq Version NM_020733.2
Organism Homo sapiens(human)
Definition Homo sapiens heart development protein with EGF like domains 1 (HEG1), mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
 NM_020733.2

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
1501
1561
1621
1681
1741
1801
1861
1921
1981
2041
2101
2161
2221
2281
2341
2401
2461
2521
2581
2641
2701
2761
2821
2881
2941
3001
3061
3121
3181
3241
3301
3361
3421
3481
3541
3601
3661
3721
3781
3841
3901
3961
4021
4081
4141
ATGGCCTCGC CGCGCGCCTC GCGGTGGCCG CCGCCGCTCC TGCTGCTGTT GCTGCCGCTG 
CTGCTGCTGC CGCCGGCGGC CCCCGGGACG CGGGACCCGC CGCCTTCCCC GGCTCGCCGC 
GCGCTGAGCC TGGCGCCCCT CGCGGGAGCG GGGCTGGAGC TGCAGCTGGA GCGCCGCCCG 
GAGCGCGAGC CGCCGCCCAC GCCGCCCCGG GAGCGCCGCG GGCCCGCGAC CCCCGGCCCC 
AGCTACAGGG CCCCTGAGCC AGGCGCCGCG ACACAGCGGG GACCCTCCGG CCGGGCCCCC 
AGAGGCGGGA GCGCGGATGC TGCCTGGAAA CATTGGCCAG AAAGTAACAC TGAGGCCCAT 
GTAGAAAACA TCACCTTCTA TCAGAATCAA GAGGACTTTT CAACAGTGTC CTCCAAAGAG 
GGCGTGATGG TTCAGACCTC TGGGAAGAGC CATGCTGCTT CGGATGCTCC AGAAAACCTC 
ACTCTACTCG CTGAAACAGC AGATGCTAGA GGAAGGAGCG GCTCTTCAAG TAGAACAAAC 
TTCACCATTT TGCCTGTTGG GTACTCACTG GAGATAGCAA CAGCTCTGAC TTCCCAGAGT 
GGCAACTTAG CCTCAGAAAG TCTTCACCTG CCATCCAGCA GTTCAGAGTT CGATGAAAGA 
ATTGCCGCTT TTCAAACAAA GAGTGGAACA GCCTCGGAGA TGGGAACAGA GAGGGCGATG 
GGGCTGTCAG AAGAATGGAC TGTGCACAGC CAAGAGGCCA CCACTTCGGC TTGGAGCCCG 
TCCTTTCTTC CTGCTTTGGA GATGGGAGAG CTGACCACGC CTTCTAGGAA GAGAAATTCC 
TCAGGACCAG ATCTCTCCTG GCTGCATTTC TACAGGACAG CAGCTTCCTC TCCTCTCTTA 
GACCTTTCCT CATCTTCTGA AAGTACAGAG AAGCTTAACA ACTCCACTGG CCTCCAGAGC 
TCCTCAGTCA GTCAAACAAA GACAATGCAT GTTGCCACCG TGTTCACTGA TGGTGGCCCG 
AGAACGCTGC GATCTTTGAC GGTCAGTCTG GGACCTGTGA GCAAGACAGA AGGCTTCCCC 
AAGGACTCCA GAATTGCCAC GACTTCATCC TCAGTCCTTC TTTCACCCTC TGCAGTGGAA 
TCGAGAAGAA ACAGTAGAGT AACTGGGAAT CCAGGGGATG AGGAATTCAT TGAACCATCC 
ACAGAAAATG AATTTGGACT TACGTCTTTG CGTTGGCAAA ATGATTCCCC AACCTTTGGA 
GAACATCAGC TTGCCAGCAG CTCTGAGGTG CAAAATGGAA GTCCCATGTC TCAGACTGAG 
ACTGTGTCTA GGTCAGTCGC ACCCATGAGA GGTGGAGAGA TCACTGCACA CTGGCTCTTG 
ACCAACAGCA CAACATCTGC AGATGTGACA GGAAGCTCTG CTTCATATCC TGAAGGTGTG 
AATGCTTCAG TGTTGACCCA GTTCTCAGAC TCTACTGTAC AGTCTGGAGG AAGTCACACA 
GCATTGGGAG ATAGGAGTTA TTCAGAGTCT TCATCTACAT CTTCCTCGGA AAGCTTGAAT 
TCATCAGCAC CACGTGGAGA ACGTTCGATC GCTGGGATTA GCTACGGTCA AGTGCGTGGC 
ACAGCTATTG AACAAAGGAC TTCCAGCGAC CACACAGACC ACACCTACCT GTCATCTACT 
TTCACCAAAG GAGAACGGGC GTTACTGTCC ATTACAGATA ACAGTTCATC CTCAGACATT 
GTGGAGAGCT CAACTTCTTA TATTAAAATC TCAAACTCTT CACATTCAGA GTATTCCTCC 
TTTTTTCATG CTCAGACTGA GAGAAGTAAC ATCTCATCCT ATGACGGGGA ATATGCTCAG 
CCTTCTACTG AGTCGCCAGT TCTGCATACA TCCAACCTTC CGTCCTACAC ACCCACCATT 
AATATGCCGA ACACTTCGGT TGTTCTGGAC ACTGATGCTG AGTTTGTTAG TGACTCCTCC 
TCCTCCTCTT CCTCCTCCTC CTCTTCTTCT TCTTCAGGGC CTCCTTTGCC TCTGCCCTCT 
GTGTCACAAT CCCACCATTT ATTTTCATCA ATTTTACCAT CAACCAGGGC CTCTGTGCAT 
CTACTAAAGT CTACCTCTGA TGCATCCACA CCATGGTCTT CCTCACCATC ACCTTTACCA 
GTATCCTTAA CGACATCTAC ATCTGCCCCA CTTTCTGTCT CACAAACAAC CTTGCCACAG 
TCATCTTCTA CCCCTGTCCT GCCCAGGGCA AGGGAGACTC CTGTGACTTC ATTTCAGACA 
TCAACAATGA CATCATTCAT GACAATGCTC CATAGTAGTC AAACTGCAGA CCTTAAGAGC 
CAGAGCACCC CACACCAAGA GAAAGTCATT ACAGAATCAA AGTCACCAAG CCTGGTGTCT 
CTGCCCACAG AGTCCACCAA AGCTGTAACA ACAAACTCTC CTTTGCCTCC ATCCTTAACA 
GAGTCCTCCA CAGAGCAAAC CCTTCCAGCC ACAAGCACCA ACTTAGCACA AATGTCTCCA 
ACTTTCACAA CTACCATTCT GAAGACCTCT CAGCCTCTTA TGACCACTCC TGGCACCCTG 
TCAAGCACAG CATCTCTGGT CACTGGCCCT ATAGCCGTAC AGACTACAGC TGGAAAACAG 
CTCTCGCTGA CCCATCCTGA AATACTAGTT CCTCAAATCT CAACAGAAGG TGGCATCAGC 
ACAGAAAGGA ACCGAGTGAT TGTGGATGCT ACCACTGGAT TGATCCCTTT GACCAGTGTA 
CCCACATCAG CAAAAGAAAT GACCACAAAG CTTGGCGTTA CAGCAGAGTA CAGCCCAGCT 
TCACGTTCCC TCGGAACATC TCCTTCTCCC CAAACCACAG TTGTTTCCAC GGCTGAAGAC 
TTGGCTCCCA AATCTGCCAC CTTTGCTGTT CAGAGCAGCA CACAGTCACC AACAACAGTG 
TCCTCTTCAG CCTCAGTCAA CAGCTGTGCT GTGAACCCTT GTCTTCACAA TGGCGAATGC 
GTCGCAGACA ACACCAGCCG TGGCTACCAC TGCAGGTGCC CGCCTTCCTG GCAAGGGGAT 
GATTGCAGTG TGGATGTGAA TGAGTGCCTG TCGAACCCCT GCCCATCCAC AGCCATGTGC 
AACAATACTC AGGGATCCTT TATCTGCAAA TGCCCGGTTG GGTACCAGTT GGAAAAAGGG 
ATATGCAATT TGGTTAGAAC CTTCGTGACA GAGTTTAAAT TAAAGAGAAC TTTTCTTAAT 
ACAACTGTGG AAAAACATTC AGACCTACAA GAAGTTGAAA ATGAGATCAC CAAAACGTTA 
AATATGTGTT TTTCAGCGTT ACCTAGTTAC ATCCGATCTA CAGTTCACGC CTCTAGGGAG 
TCCAACGCGG TGGTGATCTC ACTGCAAACA ACCTTTTCCC TGGCCTCCAA TGTGACGCTA 
TTTGACCTGG CTGATAGGAT GCAGAAATGT GTCAACTCCT GCAAGTCCTC TGCTGAGGTC 
TGCCAGCTCT TGGGATCTCA GAGGCGGATC TTTAGAGCGG GCAGCTTGTG CAAGCGGAAG 
AGTCCCGAAT GTGACAAAGA CACCTCCATC TGCACTGACC TGGACGGCGT TGCCCTGTGC 
CAGTGCAAGT CGGGATACTT TCAGTTCAAC AAGATGGACC ACTCCTGCCG AGCATGTGAA 
GATGGATATA GGCTTGAAAA TGAAACCTGC ATGAGTTGCC CATTTGGCCT TGGTGGTCTC 
AACTGTGGAA ACCCCTATCA GCTTATCACT GTGGTGATCG CAGCCGCGGG AGGTGGGCTC 
CTGCTCATCC TAGGCATCGC ACTGATTGTT ACCTGTTGCA GAAAGAATAA AAATGACATA 
AGCAAACTCA TCTTCAAAAG TGGAGATTTC CAAATGTCCC CGTATGCTGA ATACCCCAAA 
AATCCTCGCT CACAAGAATG GGGCCGAGAA GCTATTGAAA TGCATGAGAA TGGAAGTACC 
AAAAACCTCC TCCAGATGAC GGATGTGTAC TACTCGCCTA CAAGTGTAAG GAATCCAGAA 
CTTGAACGAA ACGGACTCTA CCCGGCCTAC ACTGGACTGC CAGGATCACG GCATTCTTGC 
ATTTTCCCCG GACAGTATAA CCCGTCTTTC ATCAGTGATG AAAGCAGAAG AAGAGACTAC 
TTTTAA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OHu38076
Clone ID Related Accession (Same CDS sequence) XM_005247666.1
Accession Version XM_005247666.1 Latest version! Documents for ORF clone product in default vector
Sequence Information ORF Nucleotide Sequence (Length: 4446bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ™ Seamless cloning technology
Insert Structure linear
Update Date 2019-12-05
Organism Homo sapiens(human)
Product protein HEG homolog 1 isoform X1
Comment Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000003.12) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## 

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
1501
1561
1621
1681
1741
1801
1861
1921
1981
2041
2101
2161
2221
2281
2341
2401
2461
2521
2581
2641
2701
2761
2821
2881
2941
3001
3061
3121
3181
3241
3301
3361
3421
3481
3541
3601
3661
3721
3781
3841
3901
3961
4021
4081
4141
4201
4261
4321
4381
4441
ATGGCCTCGC CGCGCGCCTC GCGGTGGCCG CCGCCGCTCC TGCTGCTGTT GCTGCCGCTG 
CTGCTGCTGC CGCCGGCGGC CCCCGGGACG CGGGACCCGC CGCCTTCCCC GGCTCGCCGC 
GCGCTGAGCC TGGCGCCCCT CGCGGGAGCG GGGCTGGAGC TGCAGCTGGA GCGCCGCCCG 
GAGCGCGAGC CGCCGCCCAC GCCGCCCCGG GAGCGCCGCG GGCCCGCGAC CCCCGGCCCC 
AGCTACAGGG CCCCTGAGCC AGGCGCCGCG ACACAGCGGG GACCCTCCGG CCGGGCCCCC 
AGAGGCGGGA GCGCGGATGC TGCCTGGAAA CATTGGCCAG AAAGTAACAC TGAGGCCCAT 
GTAGAAAACA TCACCTTCTA TCAGAATCAA GAGGACTTTT CAACAGTGTC CTCCAAAGAG 
GGCGTGATGG TTCAGACCTC TGGGAAGAGC CATGCTGCTT CGGATGCTCC AGAAAACCTC 
ACTCTACTCG CTGAAACAGC AGATGCTAGA GGAAGGAGCG GCTCTTCAAG TAGAACAAAC 
TTCACCATTT TGCCTGTTGG GTACTCACTG GAGATAGCAA CAGCTCTGAC TTCCCAGAGT 
GGCAACTTAG CCTCAGAAAG TCTTCACCTG CCATCCAGCA GTTCAGAGTT CGATGAAAGA 
ATTGCCGCTT TTCAAACAAA GAGTGGAACA GCCTCGGAGA TGGGAACAGA GAGGGCGATG 
GGGCTGTCAG AAGAATGGAC TGTGCACAGC CAAGAGGCCA CCACTTCGGC TTGGAGCCCG 
TCCTTTCTTC CTGCTTTGGA GATGGGAGAG CTGACCACGC CTTCTAGGAA GAGAAATTCC 
TCAGGACCAG ATCTCTCCTG GCTGCATTTC TACAGGACAG CAGCTTCCTC TCCTCTCTTA 
GACCTTTCCT CATCTTCTGA AAGTACAGAG AAGCTTAACA ACTCCACTGG CCTCCAGAGC 
TCCTCAGTCA GTCAAACAAA GACAATGCAT GTTGCCACCG TGTTCACTGA TGGTGGCCCG 
AGAACGCTGC GATCTTTGAC GGTCAGTCTG GGACCTGTGA GCAAGACAGA AGGCTTCCCC 
AAGGACTCCA GAATTGCCAC GACTTCATCC TCAGTCCTTC TTTCACCCTC TGCAGTGGAA 
TCGAGAAGAA ACAGTAGAGT AACTGGGAAT CCAGGGGATG AGGAATTCAT TGAACCATCC 
ACAGAAAATG AATTTGGACT TACGTCTTTG CGTTGGCAAA ATGATTCCCC AACCTTTGGA 
GAACATCAGC TTGCCAGCAG CTCTGAGGTG CAAAATGGAA GTCCCATGTC TCAGACTGAG 
ACTGTGTCTA GGTCAGTCGC ACCCATGAGA GGTGGAGAGA TCACTGCACA CTGGCTCTTG 
ACCAACAGCA CAACATCTGC AGATGTGACA GGAAGCTCTG CTTCATATCC TGAAGGTGTG 
AATGCTTCAG TGTTGACCCA GTTCTCAGAC TCTACTGTAC AGTCTGGAGG AAGTCACACA 
GCATTGGGAG ATAGGAGTTA TTCAGAGTCT TCATCTACAT CTTCCTCGGA AAGCTTGAAT 
TCATCAGCAC CACGTGGAGA ACGTTCGACC TTGGAAGACA GCCGAGAGCC AGGCCAAGCA 
CTAGGTGACA GTTCCGCCAA TGCAGAGGAC AGGACTTCTG GGGTGCCCTC TCTCGGCACC 
CACACCTTGG CTACTGTCAC TGGAAACGGG GAACGCACAC TGCGGTCTGT CACCCTCACC 
AACACCAGCA TGAGCACGAC TTCTGGGGAA GCAGGCAGCC CTGCAGCGGC CATGCACCAA 
GAAACAGAGG GTGCCTCTCT GCACGTAAAC GTGACGGACG ACATGGGCCT GGTCTCACGG 
TCACTGGCCG CCTCCAGTGC ACTCGGAGTC GCTGGGATTA GCTACGGTCA AGTGCGTGGC 
ACAGCTATTG AACAAAGGAC TTCCAGCGAC CACACAGACC ACACCTACCT GTCATCTACT 
TTCACCAAAG GAGAACGGGC GTTACTGTCC ATTACAGATA ACAGTTCATC CTCAGACATT 
GTGGAGAGCT CAACTTCTTA TATTAAAATC TCAAACTCTT CACATTCAGA GTATTCCTCC 
TTTTTTCATG CTCAGACTGA GAGAAGTAAC ATCTCATCCT ATGACGGGGA ATATGCTCAG 
CCTTCTACTG AGTCGCCAGT TCTGCATACA TCCAACCTTC CGTCCTACAC ACCCACCATT 
AATATGCCGA ACACTTCGGT TGTTCTGGAC ACTGATGCTG AGTTTGTTAG TGACTCCTCC 
TCCTCCTCTT CCTCCTCCTC CTCTTCTTCT TCTTCAGGGC CTCCTTTGCC TCTGCCCTCT 
GTGTCACAAT CCCACCATTT ATTTTCATCA ATTTTACCAT CAACCAGGGC CTCTGTGCAT 
CTACTAAAGT CTACCTCTGA TGCATCCACA CCATGGTCTT CCTCACCATC ACCTTTACCA 
GTATCCTTAA CGACATCTAC ATCTGCCCCA CTTTCTGTCT CACAAACAAC CTTGCCACAG 
TCATCTTCTA CCCCTGTCCT GCCCAGGGCA AGGGAGACTC CTGTGACTTC ATTTCAGACA 
TCAACAATGA CATCATTCAT GACAATGCTC CATAGTAGTC AAACTGCAGA CCTTAAGAGC 
CAGAGCACCC CACACCAAGA GAAAGTCATT ACAGAATCAA AGTCACCAAG CCTGGTGTCT 
CTGCCCACAG AGTCCACCAA AGCTGTAACA ACAAACTCTC CTTTGCCTCC ATCCTTAACA 
GAGTCCTCCA CAGAGCAAAC CCTTCCAGCC ACAAGCACCA ACTTAGCACA AATGTCTCCA 
ACTTTCACAA CTACCATTCT GAAGACCTCT CAGCCTCTTA TGACCACTCC TGGCACCCTG 
TCAAGCACAG CATCTCTGGT CACTGGCCCT ATAGCCGTAC AGACTACAGC TGGAAAACAG 
CTCTCGCTGA CCCATCCTGA AATACTAGTT CCTCAAATCT CAACAGAAGG TGGCATCAGC 
ACAGAAAGGA ACCGAGTGAT TGTGGATGCT ACCACTGGAT TGATCCCTTT GACCAGTGTA 
CCCACATCAG CAAAAGAAAT GACCACAAAG CTTGGCGTTA CAGCAGAGTA CAGCCCAGCT 
TCACGTTCCC TCGGAACATC TCCTTCTCCC CAAACCACAG TTGTTTCCAC GGCTGAAGAC 
TTGGCTCCCA AATCTGCCAC CTTTGCTGTT CAGAGCAGCA CACAGTCACC AACAACAGTG 
TCCTCTTCAG CCTCAGTCAA CAGCTGTGCT GTGAACCCTT GTCTTCACAA TGGCGAATGC 
GTCGCAGACA ACACCAGCCG TGGCTACCAC TGCAGGTGCC CGCCTTCCTG GCAAGGGGAT 
GATTGCAGTG TGGATGTGAA TGAGTGCCTG TCGAACCCCT GCCCATCCAC AGCCATGTGC 
AACAATACTC AGGGATCCTT TATCTGCAAA TGCCCGGTTG GGTACCAGTT GGAAAAAGGG 
ATATGCAATT TGGTTAGAAC CTTCGTGACA GAGTTTAAAT TAAAGAGAAC TTTTCTTAAT 
ACAACTGTGG AAAAACATTC AGACCTACAA GAAGTTGAAA ATGAGATCAC CAAAACGTTA 
AATATGTGTT TTTCAGCGTT ACCTAGTTAC ATCCGATCTA CAGTTCACGC CTCTAGGGAG 
TCCAACGCGG TGGTGATCTC ACTGCAAACA ACCTTTTCCC TGGCCTCCAA TGTGACGCTA 
TTTGACCTGG CTGATAGGAT GCAGAAATGT GTCAACTCCT GCAAGTCCTC TGCTGAGGTC 
TGCCAGCTCT TGGGATCTCA GAGGCGGATC TTTAGAGCGG GCAGCTTGTG CAAGCGGAAG 
AGTCCCGAAT GTGACAAAGA CACCTCCATC TGCACTGACC TGGACGGCGT TGCCCTGTGC 
CAGTGCAAGT CGGGATACTT TCAGTTCAAC AAGATGGACC ACTCCTGCCG AGCATGTGAA 
GATGGATATA GGCTTGAAAA TGAAACCTGC ATGAGTTGCC CATTTGGCCT TGGTGGTCTC 
AACTGTGGAA ACCCCTATCA GCTTATCACT GTGGTGATCG CAGCCGCGGG AGGTGGGCTC 
CTGCTCATCC TAGGCATCGC ACTGATTGTT ACCTGTTGCA GAAAGAATAA AAATGACATA 
AGCAAACTCA TCTTCAAAAG TGGAGATTTC CAAATGTCCC CGTATGCTGA ATACCCCAAA 
AATCCTCGCT CACAAGAATG GGGCCGAGAA GCTATTGAAA TGCATGAGAA TGGAAGTACC 
AAAAACCTCC TCCAGATGAC GGATGTGTAC TACTCGCCTA CAAGTGTAAG GAATCCAGAA 
CTTGAACGAA ACGGACTCTA CCCGGCCTAC ACTGGACTGC CAGGATCACG GCATTCTTGC 
ATTTTCCCCG GACAGTATAA CCCGTCTTTC ATCAGTGATG AAAGCAGAAG AAGAGACTAC 
TTTTAA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq XP_005247723.1
CDS64..4509
Translation

Target ORF information:

RefSeq Version XM_005247666.1
Organism Homo sapiens(human)
Definition Homo sapiens heart development protein with EGF like domains 1 (HEG1), transcript variant X1, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
 XM_005247666.1

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
1501
1561
1621
1681
1741
1801
1861
1921
1981
2041
2101
2161
2221
2281
2341
2401
2461
2521
2581
2641
2701
2761
2821
2881
2941
3001
3061
3121
3181
3241
3301
3361
3421
3481
3541
3601
3661
3721
3781
3841
3901
3961
4021
4081
4141
4201
4261
4321
4381
4441
ATGGCCTCGC CGCGCGCCTC GCGGTGGCCG CCGCCGCTCC TGCTGCTGTT GCTGCCGCTG 
CTGCTGCTGC CGCCGGCGGC CCCCGGGACG CGGGACCCGC CGCCTTCCCC GGCTCGCCGC 
GCGCTGAGCC TGGCGCCCCT CGCGGGAGCG GGGCTGGAGC TGCAGCTGGA GCGCCGCCCG 
GAGCGCGAGC CGCCGCCCAC GCCGCCCCGG GAGCGCCGCG GGCCCGCGAC CCCCGGCCCC 
AGCTACAGGG CCCCTGAGCC AGGCGCCGCG ACACAGCGGG GACCCTCCGG CCGGGCCCCC 
AGAGGCGGGA GCGCGGATGC TGCCTGGAAA CATTGGCCAG AAAGTAACAC TGAGGCCCAT 
GTAGAAAACA TCACCTTCTA TCAGAATCAA GAGGACTTTT CAACAGTGTC CTCCAAAGAG 
GGCGTGATGG TTCAGACCTC TGGGAAGAGC CATGCTGCTT CGGATGCTCC AGAAAACCTC 
ACTCTACTCG CTGAAACAGC AGATGCTAGA GGAAGGAGCG GCTCTTCAAG TAGAACAAAC 
TTCACCATTT TGCCTGTTGG GTACTCACTG GAGATAGCAA CAGCTCTGAC TTCCCAGAGT 
GGCAACTTAG CCTCAGAAAG TCTTCACCTG CCATCCAGCA GTTCAGAGTT CGATGAAAGA 
ATTGCCGCTT TTCAAACAAA GAGTGGAACA GCCTCGGAGA TGGGAACAGA GAGGGCGATG 
GGGCTGTCAG AAGAATGGAC TGTGCACAGC CAAGAGGCCA CCACTTCGGC TTGGAGCCCG 
TCCTTTCTTC CTGCTTTGGA GATGGGAGAG CTGACCACGC CTTCTAGGAA GAGAAATTCC 
TCAGGACCAG ATCTCTCCTG GCTGCATTTC TACAGGACAG CAGCTTCCTC TCCTCTCTTA 
GACCTTTCCT CATCTTCTGA AAGTACAGAG AAGCTTAACA ACTCCACTGG CCTCCAGAGC 
TCCTCAGTCA GTCAAACAAA GACAATGCAT GTTGCCACCG TGTTCACTGA TGGTGGCCCG 
AGAACGCTGC GATCTTTGAC GGTCAGTCTG GGACCTGTGA GCAAGACAGA AGGCTTCCCC 
AAGGACTCCA GAATTGCCAC GACTTCATCC TCAGTCCTTC TTTCACCCTC TGCAGTGGAA 
TCGAGAAGAA ACAGTAGAGT AACTGGGAAT CCAGGGGATG AGGAATTCAT TGAACCATCC 
ACAGAAAATG AATTTGGACT TACGTCTTTG CGTTGGCAAA ATGATTCCCC AACCTTTGGA 
GAACATCAGC TTGCCAGCAG CTCTGAGGTG CAAAATGGAA GTCCCATGTC TCAGACTGAG 
ACTGTGTCTA GGTCAGTCGC ACCCATGAGA GGTGGAGAGA TCACTGCACA CTGGCTCTTG 
ACCAACAGCA CAACATCTGC AGATGTGACA GGAAGCTCTG CTTCATATCC TGAAGGTGTG 
AATGCTTCAG TGTTGACCCA GTTCTCAGAC TCTACTGTAC AGTCTGGAGG AAGTCACACA 
GCATTGGGAG ATAGGAGTTA TTCAGAGTCT TCATCTACAT CTTCCTCGGA AAGCTTGAAT 
TCATCAGCAC CACGTGGAGA ACGTTCGACC TTGGAAGACA GCCGAGAGCC AGGCCAAGCA 
CTAGGTGACA GTTCCGCCAA TGCAGAGGAC AGGACTTCTG GGGTGCCCTC TCTCGGCACC 
CACACCTTGG CTACTGTCAC TGGAAACGGG GAACGCACAC TGCGGTCTGT CACCCTCACC 
AACACCAGCA TGAGCACGAC TTCTGGGGAA GCAGGCAGCC CTGCAGCGGC CATGCACCAA 
GAAACAGAGG GTGCCTCTCT GCACGTAAAC GTGACGGACG ACATGGGCCT GGTCTCACGG 
TCACTGGCCG CCTCCAGTGC ACTCGGAGTC GCTGGGATTA GCTACGGTCA AGTGCGTGGC 
ACAGCTATTG AACAAAGGAC TTCCAGCGAC CACACAGACC ACACCTACCT GTCATCTACT 
TTCACCAAAG GAGAACGGGC GTTACTGTCC ATTACAGATA ACAGTTCATC CTCAGACATT 
GTGGAGAGCT CAACTTCTTA TATTAAAATC TCAAACTCTT CACATTCAGA GTATTCCTCC 
TTTTTTCATG CTCAGACTGA GAGAAGTAAC ATCTCATCCT ATGACGGGGA ATATGCTCAG 
CCTTCTACTG AGTCGCCAGT TCTGCATACA TCCAACCTTC CGTCCTACAC ACCCACCATT 
AATATGCCGA ACACTTCGGT TGTTCTGGAC ACTGATGCTG AGTTTGTTAG TGACTCCTCC 
TCCTCCTCTT CCTCCTCCTC CTCTTCTTCT TCTTCAGGGC CTCCTTTGCC TCTGCCCTCT 
GTGTCACAAT CCCACCATTT ATTTTCATCA ATTTTACCAT CAACCAGGGC CTCTGTGCAT 
CTACTAAAGT CTACCTCTGA TGCATCCACA CCATGGTCTT CCTCACCATC ACCTTTACCA 
GTATCCTTAA CGACATCTAC ATCTGCCCCA CTTTCTGTCT CACAAACAAC CTTGCCACAG 
TCATCTTCTA CCCCTGTCCT GCCCAGGGCA AGGGAGACTC CTGTGACTTC ATTTCAGACA 
TCAACAATGA CATCATTCAT GACAATGCTC CATAGTAGTC AAACTGCAGA CCTTAAGAGC 
CAGAGCACCC CACACCAAGA GAAAGTCATT ACAGAATCAA AGTCACCAAG CCTGGTGTCT 
CTGCCCACAG AGTCCACCAA AGCTGTAACA ACAAACTCTC CTTTGCCTCC ATCCTTAACA 
GAGTCCTCCA CAGAGCAAAC CCTTCCAGCC ACAAGCACCA ACTTAGCACA AATGTCTCCA 
ACTTTCACAA CTACCATTCT GAAGACCTCT CAGCCTCTTA TGACCACTCC TGGCACCCTG 
TCAAGCACAG CATCTCTGGT CACTGGCCCT ATAGCCGTAC AGACTACAGC TGGAAAACAG 
CTCTCGCTGA CCCATCCTGA AATACTAGTT CCTCAAATCT CAACAGAAGG TGGCATCAGC 
ACAGAAAGGA ACCGAGTGAT TGTGGATGCT ACCACTGGAT TGATCCCTTT GACCAGTGTA 
CCCACATCAG CAAAAGAAAT GACCACAAAG CTTGGCGTTA CAGCAGAGTA CAGCCCAGCT 
TCACGTTCCC TCGGAACATC TCCTTCTCCC CAAACCACAG TTGTTTCCAC GGCTGAAGAC 
TTGGCTCCCA AATCTGCCAC CTTTGCTGTT CAGAGCAGCA CACAGTCACC AACAACAGTG 
TCCTCTTCAG CCTCAGTCAA CAGCTGTGCT GTGAACCCTT GTCTTCACAA TGGCGAATGC 
GTCGCAGACA ACACCAGCCG TGGCTACCAC TGCAGGTGCC CGCCTTCCTG GCAAGGGGAT 
GATTGCAGTG TGGATGTGAA TGAGTGCCTG TCGAACCCCT GCCCATCCAC AGCCATGTGC 
AACAATACTC AGGGATCCTT TATCTGCAAA TGCCCGGTTG GGTACCAGTT GGAAAAAGGG 
ATATGCAATT TGGTTAGAAC CTTCGTGACA GAGTTTAAAT TAAAGAGAAC TTTTCTTAAT 
ACAACTGTGG AAAAACATTC AGACCTACAA GAAGTTGAAA ATGAGATCAC CAAAACGTTA 
AATATGTGTT TTTCAGCGTT ACCTAGTTAC ATCCGATCTA CAGTTCACGC CTCTAGGGAG 
TCCAACGCGG TGGTGATCTC ACTGCAAACA ACCTTTTCCC TGGCCTCCAA TGTGACGCTA 
TTTGACCTGG CTGATAGGAT GCAGAAATGT GTCAACTCCT GCAAGTCCTC TGCTGAGGTC 
TGCCAGCTCT TGGGATCTCA GAGGCGGATC TTTAGAGCGG GCAGCTTGTG CAAGCGGAAG 
AGTCCCGAAT GTGACAAAGA CACCTCCATC TGCACTGACC TGGACGGCGT TGCCCTGTGC 
CAGTGCAAGT CGGGATACTT TCAGTTCAAC AAGATGGACC ACTCCTGCCG AGCATGTGAA 
GATGGATATA GGCTTGAAAA TGAAACCTGC ATGAGTTGCC CATTTGGCCT TGGTGGTCTC 
AACTGTGGAA ACCCCTATCA GCTTATCACT GTGGTGATCG CAGCCGCGGG AGGTGGGCTC 
CTGCTCATCC TAGGCATCGC ACTGATTGTT ACCTGTTGCA GAAAGAATAA AAATGACATA 
AGCAAACTCA TCTTCAAAAG TGGAGATTTC CAAATGTCCC CGTATGCTGA ATACCCCAAA 
AATCCTCGCT CACAAGAATG GGGCCGAGAA GCTATTGAAA TGCATGAGAA TGGAAGTACC 
AAAAACCTCC TCCAGATGAC GGATGTGTAC TACTCGCCTA CAAGTGTAAG GAATCCAGAA 
CTTGAACGAA ACGGACTCTA CCCGGCCTAC ACTGGACTGC CAGGATCACG GCATTCTTGC 
ATTTTCCCCG GACAGTATAA CCCGTCTTTC ATCAGTGATG AAAGCAGAAG AAGAGACTAC 
TTTTAA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

PubMed

book

HEG1 is a novel mucin-like membrane protein that serves as a diagnostic and therapeutic target for malignant mesothelioma.
Scientific reports745768(2017 Mar)
Tsuji S,Washimi K,Kageyama T,Yamashita M,Yoshihara M,Matsuura R,Yokose T,Kameda Y,Hayashi H,Morohoshi T,Tsuura Y,Yusa T,Sato T,Togayachi A,Narimatsu H,Nagasaki T,Nakamoto K,Moriwaki Y,Misawa H,Hiroshima K,Miyagi Y,Imai K


book

Heart of glass anchors Rasip1 at endothelial cell-cell junctions to support vascular integrity.
eLife5e11394(2016 Jan)
de Kreuk BJ,Gingras AR,Knight JD,Liu JJ,Gingras AC,Ginsberg MH


book

Cerebral cavernous malformations arise independent of the heart of glass receptor.
Stroke45(5)1505-1509(2014 May)
Zheng X,Riant F,Bergametti F,Myers CD,Tang AT,Kleaveland B,Pan W,Yang J,Tournier-Lasserve E,Kahn ML


book

The structure of the ternary complex of Krev interaction trapped 1 (KRIT1) bound to both the Rap1 GTPase and the heart of glass (HEG1) cytoplasmic tail.
The Journal of biological chemistry288(33)23639-49(2013 Aug)
Gingras AR,Puzon-McLaughlin W,Ginsberg MH