Gene Symbol | CEP126 |
Entrez Gene ID | 57562 |
Full Name | centrosomal protein 126 |
Synonyms | KIAA1377 |
General protein information |
|
Gene Type | protein-coding |
Organism | Homo sapiens(human) |
Genome | |
Disorder MIM: |
ORF » Species Summary » Homo sapiens » CEP126 cDNA ORF clone
Gene Symbol | CEP126 |
Entrez Gene ID | 57562 |
Full Name | centrosomal protein 126 |
Synonyms | KIAA1377 |
General protein information |
|
Gene Type | protein-coding |
Organism | Homo sapiens(human) |
Genome | |
Disorder MIM: |
mRNA | Protein | Name |
---|---|---|
NM_001363543.1 | NP_001350472.1 | centrosomal protein of 126 kDa isoform 2 |
NM_001363543.2 | NP_001350472.1 | centrosomal protein of 126 kDa isoform 2 |
NM_020802.4 | NP_065853.3 | centrosomal protein of 126 kDa isoform 1 |
XM_005271627.4 | XP_005271684.2 | centrosomal protein of 126 kDa isoform X1 |
XM_005271627.5 | XP_005271684.2 | centrosomal protein of 126 kDa isoform X1 |
NM_020802.3 | NP_065853.3 | centrosomal protein of 126 kDa isoform 1 |
LOC701911 | XP_001095649.2 | |
Bos taurus (cattle) | KIAA1377 | XP_003586983.2 |
Mus musculus (house mouse) | AK129341 | NP_001038989.1 |
Gallus gallus (chicken) | KIAA1377 | XP_004938895.1 |
Homo sapiens (human) | KIAA1377 | NP_065853.2 |
Pan troglodytes (chimpanzee) | KIAA1377 | XP_508716.3 |
Canis lupus familiaris (dog) | KIAA1377 | XP_005620369.1 |
Rattus norvegicus (Norway rat) | RGD1563556 | XP_006242568.1 |
Cep126 is required for pericentriolar satellite localisation to the centrosome and for primary cilium formation.
Bonavita R, Walas D, Brown AK, Luini A, Stephens DJ, Colanzi A
Biology of the cell106(8)254-67(2014 Aug)
Identification of novel mitosis regulators through data mining with human centromere/kinetochore proteins as group queries.
Tipton AR, Wang K, Oladimeji P, Sufi S, Gu Z, Liu ST
BMC cell biology1315(2012 Jun)
Exome sequencing identifies KIAA1377 and C5orf42 as susceptibility genes for monomelic amyotrophy.
Lim YM, Koh I, Park YM, Kim JJ, Kim DS, Kim HJ, Baik KH, Choi HY, Yang GS, Also-Rallo E, Tizzano EF, Gamez J, Park K, Yoo HW, Lee JK, Kim KK
Neuromuscular disorders : NMD22(5)394-400(2012 May)
From midbody protein-protein interaction network construction to novel regulators in cytokinesis.
Chen TC, Lee SA, Hong TM, Shih JY, Lai JM, Chiou HY, Yang SC, Chan CH, Kao CY, Yang PC, Huang CY
Journal of proteome research8(11)4943-53(2009 Nov)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
CEP126 is a regulator of microtubule organisation at the centrosome that acts through modulation of the transport of pericentriolar satellites, and consequently, of the organisation of cell structure
Title: Cep126 is required for pericentriolar satellite localisation to the centrosome and for primary cilium formation.
KIAA1377 and C5orf42 gene synergistically play a role as susceptibility genes for monomelic amyotrophy.
Title: Exome sequencing identifies KIAA1377 and C5orf42 as susceptibility genes for monomelic amyotrophy.
The following CEP126 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the CEP126 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
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CloneID | OHu16041 | |
Clone ID Related Accession (Same CDS sequence) | NM_020802.4 , NM_020802.3 | |
Accession Version | NM_020802.4 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 3354bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-10-20 | |
Organism | Homo sapiens(human) | |
Product | centrosomal protein of 126 kDa isoform 1 | |
Comment | Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AP003383.2, DB455438.3, BX647415.1 and AB037798.1. On May 17, 2019 this sequence version replaced NM_020802.3. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. ##Evidence-Data-START## Transcript exon combination :: SRR1803612.214391.1, SRR1660805.180015.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1968189, SAMEA1968540 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000263468.13/ ENSP00000263468.8 RefSeq Select criteria :: based on conservation, expression, longest protein ##RefSeq-Attributes-END## COMPLETENESS: complete on the 3' end. |
1 | ATGCTGGCGG GGAGGCCCGG AACCCGGAGC GCGGTCGGGG AACTGGGCAC TGAATCATCG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_065853.3 |
CDS | 276..3629 |
Translation |
Target ORF information:
Target ORF information:
|
NM_020802.4 |
1 | ATGCTGGCGG GGAGGCCCGG AACCCGGAGC GCGGTCGGGG AACTGGGCAC TGAATCATCG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OHu16041 | |
Clone ID Related Accession (Same CDS sequence) | NM_020802.4 , NM_020802.3 | |
Accession Version | NM_020802.3 | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 3354bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2018-06-29 | |
Organism | Homo sapiens(human) | |
Product | centrosomal protein of 126 kDa isoform 1 | |
Comment | Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from DB455438.3, BX647415.1, AP003383.2 and AB037798.1. On Apr 15, 2014 this sequence version replaced NM_020802.2. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. ##Evidence-Data-START## Transcript exon combination :: SRR1660805.180015.1, SRR1803612.214391.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1968189, SAMEA1968540 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end. |
1 | ATGCTGGCGG GGAGGCCCGG AACCCGGAGC GCGGTCGGGG AACTGGGCAC TGAATCATCG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_065853.3 |
CDS | 271..3624 |
Translation |
Target ORF information:
Target ORF information:
|
NM_020802.3 |
1 | ATGCTGGCGG GGAGGCCCGG AACCCGGAGC GCGGTCGGGG AACTGGGCAC TGAATCATCG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OHu106767 | |
Clone ID Related Accession (Same CDS sequence) | NM_001363543.1 , NM_001363543.2 | |
Accession Version | NM_001363543.1 | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 2757bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2018-06-30 | |
Organism | Homo sapiens(human) | |
Product | centrosomal protein of 126 kDa isoform 2 | |
Comment | Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AP003383.2 and KF455480.1. On May 24, 2018 this sequence version replaced XM_024448625.1. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. ##Evidence-Data-START## Transcript exon combination :: SRR1803613.136840.1, SRR1803615.92185.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1968540, SAMEA1968968 [ECO:0000348] ##Evidence-Data-END## |
1 | ATGAATGAAA ACATGAGGGC AACCTTGGCT ACTAGCAAAA ATGTGTTCCA GCTTAAACTG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_001350472.1 |
CDS | 1550..4306 |
Translation |
Target ORF information:
Target ORF information:
|
NM_001363543.1 |
1 | ATGAATGAAA ACATGAGGGC AACCTTGGCT ACTAGCAAAA ATGTGTTCCA GCTTAAACTG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OHu106767 | |
Clone ID Related Accession (Same CDS sequence) | NM_001363543.1 , NM_001363543.2 | |
Accession Version | NM_001363543.2 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 2757bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-09-15 | |
Organism | Homo sapiens(human) | |
Product | centrosomal protein of 126 kDa isoform 2 | |
Comment | Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AP003383.2 and KF455480.1. On May 31, 2019 this sequence version replaced NM_001363543.1. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. ##Evidence-Data-START## Transcript exon combination :: SRR1803613.136840.1, SRR1803615.92185.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1968540, SAMEA1968968 [ECO:0000348] ##Evidence-Data-END## |
1 | ATGAATGAAA ACATGAGGGC AACCTTGGCT ACTAGCAAAA ATGTGTTCCA GCTTAAACTG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_001350472.1 |
CDS | 1555..4311 |
Translation |
Target ORF information:
Target ORF information:
|
NM_001363543.2 |
1 | ATGAATGAAA ACATGAGGGC AACCTTGGCT ACTAGCAAAA ATGTGTTCCA GCTTAAACTG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OHu45842 | |
Clone ID Related Accession (Same CDS sequence) | XM_005271627.4 , XM_005271627.5 | |
Accession Version | XM_005271627.4 | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 3246bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2016-06-05 | |
Organism | Homo sapiens(human) | |
Product | centrosomal protein of 126 kDa isoform X1 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000011.10) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 6, 2016 this sequence version replaced XM_005271627.3. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Homo sapiens Annotation Release 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGCTGGCGG GGAGGCCCGG AACCCGGAGC GCGGTCGGGG AACTGGGCAC TGAATCATCG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_005271684.2 |
CDS | 2..3247 |
Translation |
Target ORF information:
Target ORF information:
|
XM_005271627.4 |
1 | ATGCTGGCGG GGAGGCCCGG AACCCGGAGC GCGGTCGGGG AACTGGGCAC TGAATCATCG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OHu45842 | |
Clone ID Related Accession (Same CDS sequence) | XM_005271627.4 , XM_005271627.5 | |
Accession Version | XM_005271627.5 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 3246bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2018-03-25 | |
Organism | Homo sapiens(human) | |
Product | centrosomal protein of 126 kDa isoform X1 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000011.10) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Mar 26, 2018 this sequence version replaced XM_005271627.4. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Homo sapiens Annotation Release 109 Annotation Version :: 109 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGCTGGCGG GGAGGCCCGG AACCCGGAGC GCGGTCGGGG AACTGGGCAC TGAATCATCG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_005271684.2 |
CDS | 264..3509 |
Translation |
Target ORF information:
Target ORF information:
|
XM_005271627.5 |
1 | ATGCTGGCGG GGAGGCCCGG AACCCGGAGC GCGGTCGGGG AACTGGGCAC TGAATCATCG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
Cep126 is required for pericentriolar satellite localisation to the centrosome and for primary cilium formation. |
Identification of novel mitosis regulators through data mining with human centromere/kinetochore proteins as group queries. |
Exome sequencing identifies KIAA1377 and C5orf42 as susceptibility genes for monomelic amyotrophy. |
From midbody protein-protein interaction network construction to novel regulators in cytokinesis. |