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PTPN11 cDNA ORF clone, Homo sapiens (human)

Gene Symbol PTPN11
Entrez Gene ID 5781
Full Name protein tyrosine phosphatase, non-receptor type 11
Synonyms BPTP3, CFC, NS1, PTP-1D, PTP2C, SH-PTP2, SH-PTP3, SHP2
General protein information
Preferred Names
tyrosine-protein phosphatase non-receptor type 11
Names
tyrosine-protein phosphatase non-receptor type 11
PTP-2C
protein-tyrosine phosphatase 1D
protein-tyrosine phosphatase 2C
NP_002825.3
NP_542168.1
Gene Type protein-coding
Organism Homo sapiens (human)
Genome

12

12q24

Summary The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP contains two tandem Src homology-2 domains, which function as phospho-tyrosine binding domains and mediate the interaction of this PTP with its substrates. This PTP is widely expressed in most tissues and plays a regulatory role in various cell signaling events that are important for a diversity of cell functions, such as mitogenic activation, metabolic control, transcription regulation, and cell migration. Mutations in this gene are a cause of Noonan syndrome as well as acute myeloid leukemia. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2012]. lac of sum
Disorder MIM:

176876

Disorder Html: Noonan syndrome 1, 163950 (3); LEOPARD syndrome 1, 151100 (3);

mRNA and Protein(s)

mRNA Protein Name
XM_006719526 XP_006719589 tyrosine-protein phosphatase non-receptor type 11 isoform X1
XM_011538613 XP_011536915 tyrosine-protein phosphatase non-receptor type 11 isoform X2
XM_006719527 XP_006719590 tyrosine-protein phosphatase non-receptor type 11 isoform X3
NM_002834 NP_002825 tyrosine-protein phosphatase non-receptor type 11 isoform 1
NM_080601 NP_542168 tyrosine-protein phosphatase non-receptor type 11 isoform 2



Homo sapiens (human) PTPN11 NP_002825.3
Pan troglodytes (chimpanzee) PTPN11 XP_522535.3
Macaca mulatta (Rhesus monkey) PTPN11 XP_001110117.1
Canis lupus familiaris (dog) PTPN11 XP_005636307.1
Bos taurus (cattle) PTPN11 XP_002694636.2
Mus musculus (house mouse) Ptpn11 NP_035332.1
Rattus norvegicus (Norway rat) Ptpn11 NP_001171064.1
Gallus gallus (chicken) PTPN11 NP_990299.1
Danio rerio (zebrafish) ptpn11a NP_956140.1
Drosophila melanogaster (fruit fly) csw NP_001259174.1


GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following PTPN11 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the PTPN11 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

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***CloneID RefSeq Accession Definition **Vector *Turnaround time Price (USD) Select
OHu46740 XM_006719526 PREDICTED: Homo sapiens protein tyrosine phosphatase, non-receptor type 11 (PTPN11), transcript variant X1, mRNA. pcDNA3.1+/C-(K)DYK or customized vector 7-9 $307.30
$439.00
OHu60047 XM_011538613 PREDICTED: Homo sapiens protein tyrosine phosphatase, non-receptor type 11 (PTPN11), transcript variant X2, mRNA. pcDNA3.1+/C-(K)DYK or customized vector 7-9 $307.30
$439.00
OHu46741 XM_006719527 PREDICTED: Homo sapiens protein tyrosine phosphatase, non-receptor type 11 (PTPN11), transcript variant X3, mRNA. pcDNA3.1+/C-(K)DYK or customized vector 7-9 $307.30
$439.00
OHu25096
NM_002834 Homo sapiens protein tyrosine phosphatase, non-receptor type 11 (PTPN11), transcript variant 1, mRNA. pcDNA3.1+/C-(K)DYK or customized vector
in pcDNA3.1+/C-(K)DYK
$249.50-$349.30
$499.00
OHu24957
NM_080601 Homo sapiens protein tyrosine phosphatase, non-receptor type 11 (PTPN11), transcript variant 2, mRNA. pcDNA3.1+/C-(K)DYK or customized vector
in pcDNA3.1+/C-(K)DYK
$159.50-$223.30
$319.00

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.


CloneID OHu46740
Clone ID Related Accession (Same CDS sequence) XM_006719526
Accession Version XM_006719526.1 Documents for ORF clone product in dufault vector
Sequence Information ORF Nucleotide Sequence (Length: 1794bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ® Seamless cloning technology
Insert Structure linear
Update Date 12-MAR-2015
Organism Homo sapiens (human)
Product tyrosine-protein phosphatase non-receptor type 11 isoform X1
Comment MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NT_029419.13) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Homo sapiens Annotation Release 107 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 6.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
1501
1561
1621
1681
1741
ATGACATCGC GGAGATGGTT TCACCCAAAT ATCACTGGTG TGGAGGCAGA AAACCTACTG 
TTGACAAGAG GAGTTGATGG CAGTTTTTTG GCAAGGCCTA GTAAAAGTAA CCCTGGAGAC
TTCACACTTT CCGTTAGAAG AAATGGAGCT GTCACCCACA TCAAGATTCA GAACACTGGT
GATTACTATG ACCTGTATGG AGGGGAGAAA TTTGCCACTT TGGCTGAGTT GGTCCAGTAT
TACATGGAAC ATCACGGGCA ATTAAAAGAG AAGAATGGAG ATGTCATTGA GCTTAAATAT
CCTCTGAACT GTGCAGATCC TACCTCTGAA AGGTGGTTTC ATGGACATCT CTCTGGGAAA
GAAGCAGAGA AATTATTAAC TGAAAAAGGA AAACATGGTA GTTTTCTTGT ACGAGAGAGC
CAGAGCCACC CTGGAGATTT TGTTCTTTCT GTGCGCACTG GTGATGACAA AGGGGAGAGC
AATGACGGCA AGTCTAAAGT GACCCATGTT ATGATTCGCT GTCAGGAACT GAAATACGAC
GTTGGTGGAG GAGAACGGTT TGATTCTTTG ACAGATCTTG TGGAACATTA TAAGAAGAAT
CCTATGGTGG AAACATTGGG TACAGTACTA CAACTCAAGC AGCCCCTTAA CACGACTCGT
ATAAATGCTG CTGAAATAGA AAGCAGAGTT CGAGAACTAA GCAAATTAGC TGAGACCACA
GATAAAGTCA AACAAGGCTT TTGGGAAGAA TTTGAGACAC TACAACAACA GGAGTGCAAA
CTTCTCTACA GCCGAAAAGA GGGTCAAAGG CAAGAAAACA AAAACAAAAA TAGATATAAA
AACATCCTGC CCTTTGATCA TACCAGGGTT GTCCTACACG ATGGTGATCC CAATGAGCCT
GTTTCAGATT ACATCAATGC AAATATCATC ATGCCTGAAT TTGAAACCAA GTGCAACAAT
TCAAAGCCCA AAAAGAGTTA CATTGCCACA CAAGGCTGCC TGCAAAACAC GGTGAATGAC
TTTTGGCGGA TGGTGTTCCA AGAAAACTCC CGAGTGATTG TCATGACAAC GAAAGAAGTG
GAGAGAGGAA AGAGTAAATG TGTCAAATAC TGGCCTGATG AGTATGCTCT AAAAGAATAT
GGCGTCATGC GTGTTAGGAA CGTCAAAGAA AGCGCCGCTC ATGACTATAC GCTAAGAGAA
CTTAAACTTT CAAAGGTTGG ACAAGCTCTA CTCCAGGGGA ATACGGAGAG AACGGTCTGG
CAATACCACT TTCGGACCTG GCCGGACCAC GGCGTGCCCA GCGACCCTGG GGGCGTGCTG
GACTTCCTGG AGGAGGTGCA CCATAAGCAG GAGAGCATCA TGGATGCAGG GCCGGTCGTG
GTGCACTGCA GTGCTGGAAT TGGCCGGACA GGGACGTTCA TTGTGATTGA TATTCTTATT
GACATCATCA GAGAGAAAGG TGTTGACTGC GATATTGACG TTCCCAAAAC CATCCAGATG
GTGCGGTCTC AGAGGTCAGG GATGGTCCAG ACAGAAGCAC AGTACCGATT TATCTATATG
GCGGTCCAGC ATTATATTGA AACACTACAG CGCAGGATTG AAGAAGAGCA GAAAAGCAAG
AGGAAAGGGC ACGAATATAC AAATATTAAG TATTCTCTAG CGGACCAGAC GAGTGGAGAT
CAGAGCCCTC TCCCGCCTTG TACTCCAACG CCACCCTGTG CAGAAATGAG AGAAGACAGT
GCTAGAGTCT ATGAAAACGT GGGCCTGATG CAACAGCAGA AAAGTTTCAG ATGA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq XP_006719589.1
CDS166..1959
Misc Feature(1)178..474(+)
Misc Feature(2)202..330(+)
Misc Feature(3)319..444(+)
Misc Feature(4)496..819(+)
Misc Feature(5)580..606(+)
Misc Feature(6)673..756(+)
Misc Feature(7)901..1737(+)
Misc Feature(8)991..1734(+)
Misc Feature(9)1450..1575(+)
Translation

Target ORF information:

RefSeq Version XM_006719526
Organism Homo sapiens (human)
Definition PREDICTED: Homo sapiens protein tyrosine phosphatase, non-receptor type 11 (PTPN11), transcript variant X1, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
XM_006719526

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
1501
1561
1621
1681
1741
ATGACATCGC GGAGATGGTT TCACCCAAAT ATCACTGGTG TGGAGGCAGA AAACCTACTG 
TTGACAAGAG GAGTTGATGG CAGTTTTTTG GCAAGGCCTA GTAAAAGTAA CCCTGGAGAC
TTCACACTTT CCGTTAGAAG AAATGGAGCT GTCACCCACA TCAAGATTCA GAACACTGGT
GATTACTATG ACCTGTATGG AGGGGAGAAA TTTGCCACTT TGGCTGAGTT GGTCCAGTAT
TACATGGAAC ATCACGGGCA ATTAAAAGAG AAGAATGGAG ATGTCATTGA GCTTAAATAT
CCTCTGAACT GTGCAGATCC TACCTCTGAA AGGTGGTTTC ATGGACATCT CTCTGGGAAA
GAAGCAGAGA AATTATTAAC TGAAAAAGGA AAACATGGTA GTTTTCTTGT ACGAGAGAGC
CAGAGCCACC CTGGAGATTT TGTTCTTTCT GTGCGCACTG GTGATGACAA AGGGGAGAGC
AATGACGGCA AGTCTAAAGT GACCCATGTT ATGATTCGCT GTCAGGAACT GAAATACGAC
GTTGGTGGAG GAGAACGGTT TGATTCTTTG ACAGATCTTG TGGAACATTA TAAGAAGAAT
CCTATGGTGG AAACATTGGG TACAGTACTA CAACTCAAGC AGCCCCTTAA CACGACTCGT
ATAAATGCTG CTGAAATAGA AAGCAGAGTT CGAGAACTAA GCAAATTAGC TGAGACCACA
GATAAAGTCA AACAAGGCTT TTGGGAAGAA TTTGAGACAC TACAACAACA GGAGTGCAAA
CTTCTCTACA GCCGAAAAGA GGGTCAAAGG CAAGAAAACA AAAACAAAAA TAGATATAAA
AACATCCTGC CCTTTGATCA TACCAGGGTT GTCCTACACG ATGGTGATCC CAATGAGCCT
GTTTCAGATT ACATCAATGC AAATATCATC ATGCCTGAAT TTGAAACCAA GTGCAACAAT
TCAAAGCCCA AAAAGAGTTA CATTGCCACA CAAGGCTGCC TGCAAAACAC GGTGAATGAC
TTTTGGCGGA TGGTGTTCCA AGAAAACTCC CGAGTGATTG TCATGACAAC GAAAGAAGTG
GAGAGAGGAA AGAGTAAATG TGTCAAATAC TGGCCTGATG AGTATGCTCT AAAAGAATAT
GGCGTCATGC GTGTTAGGAA CGTCAAAGAA AGCGCCGCTC ATGACTATAC GCTAAGAGAA
CTTAAACTTT CAAAGGTTGG ACAAGCTCTA CTCCAGGGGA ATACGGAGAG AACGGTCTGG
CAATACCACT TTCGGACCTG GCCGGACCAC GGCGTGCCCA GCGACCCTGG GGGCGTGCTG
GACTTCCTGG AGGAGGTGCA CCATAAGCAG GAGAGCATCA TGGATGCAGG GCCGGTCGTG
GTGCACTGCA GTGCTGGAAT TGGCCGGACA GGGACGTTCA TTGTGATTGA TATTCTTATT
GACATCATCA GAGAGAAAGG TGTTGACTGC GATATTGACG TTCCCAAAAC CATCCAGATG
GTGCGGTCTC AGAGGTCAGG GATGGTCCAG ACAGAAGCAC AGTACCGATT TATCTATATG
GCGGTCCAGC ATTATATTGA AACACTACAG CGCAGGATTG AAGAAGAGCA GAAAAGCAAG
AGGAAAGGGC ACGAATATAC AAATATTAAG TATTCTCTAG CGGACCAGAC GAGTGGAGAT
CAGAGCCCTC TCCCGCCTTG TACTCCAACG CCACCCTGTG CAGAAATGAG AGAAGACAGT
GCTAGAGTCT ATGAAAACGT GGGCCTGATG CAACAGCAGA AAAGTTTCAG ATGA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OHu60047
Clone ID Related Accession (Same CDS sequence) XM_011538613
Accession Version XM_011538613.1 Documents for ORF clone product in dufault vector
Sequence Information ORF Nucleotide Sequence (Length: 1791bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ® Seamless cloning technology
Insert Structure linear
Update Date 12-MAR-2015
Organism Homo sapiens (human)
Product tyrosine-protein phosphatase non-receptor type 11 isoform X2
Comment MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NT_029419.13) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Homo sapiens Annotation Release 107 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 6.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
1501
1561
1621
1681
1741
ATGACATCGC GGAGATGGTT TCACCCAAAT ATCACTGGTG TGGAGGCAGA AAACCTACTG 
TTGACAAGAG GAGTTGATGG CAGTTTTTTG GCAAGGCCTA GTAAAAGTAA CCCTGGAGAC
TTCACACTTT CCGTTAGAAA TGGAGCTGTC ACCCACATCA AGATTCAGAA CACTGGTGAT
TACTATGACC TGTATGGAGG GGAGAAATTT GCCACTTTGG CTGAGTTGGT CCAGTATTAC
ATGGAACATC ACGGGCAATT AAAAGAGAAG AATGGAGATG TCATTGAGCT TAAATATCCT
CTGAACTGTG CAGATCCTAC CTCTGAAAGG TGGTTTCATG GACATCTCTC TGGGAAAGAA
GCAGAGAAAT TATTAACTGA AAAAGGAAAA CATGGTAGTT TTCTTGTACG AGAGAGCCAG
AGCCACCCTG GAGATTTTGT TCTTTCTGTG CGCACTGGTG ATGACAAAGG GGAGAGCAAT
GACGGCAAGT CTAAAGTGAC CCATGTTATG ATTCGCTGTC AGGAACTGAA ATACGACGTT
GGTGGAGGAG AACGGTTTGA TTCTTTGACA GATCTTGTGG AACATTATAA GAAGAATCCT
ATGGTGGAAA CATTGGGTAC AGTACTACAA CTCAAGCAGC CCCTTAACAC GACTCGTATA
AATGCTGCTG AAATAGAAAG CAGAGTTCGA GAACTAAGCA AATTAGCTGA GACCACAGAT
AAAGTCAAAC AAGGCTTTTG GGAAGAATTT GAGACACTAC AACAACAGGA GTGCAAACTT
CTCTACAGCC GAAAAGAGGG TCAAAGGCAA GAAAACAAAA ACAAAAATAG ATATAAAAAC
ATCCTGCCCT TTGATCATAC CAGGGTTGTC CTACACGATG GTGATCCCAA TGAGCCTGTT
TCAGATTACA TCAATGCAAA TATCATCATG CCTGAATTTG AAACCAAGTG CAACAATTCA
AAGCCCAAAA AGAGTTACAT TGCCACACAA GGCTGCCTGC AAAACACGGT GAATGACTTT
TGGCGGATGG TGTTCCAAGA AAACTCCCGA GTGATTGTCA TGACAACGAA AGAAGTGGAG
AGAGGAAAGA GTAAATGTGT CAAATACTGG CCTGATGAGT ATGCTCTAAA AGAATATGGC
GTCATGCGTG TTAGGAACGT CAAAGAAAGC GCCGCTCATG ACTATACGCT AAGAGAACTT
AAACTTTCAA AGGTTGGACA AGCTCTACTC CAGGGGAATA CGGAGAGAAC GGTCTGGCAA
TACCACTTTC GGACCTGGCC GGACCACGGC GTGCCCAGCG ACCCTGGGGG CGTGCTGGAC
TTCCTGGAGG AGGTGCACCA TAAGCAGGAG AGCATCATGG ATGCAGGGCC GGTCGTGGTG
CACTGCAGTG CTGGAATTGG CCGGACAGGG ACGTTCATTG TGATTGATAT TCTTATTGAC
ATCATCAGAG AGAAAGGTGT TGACTGCGAT ATTGACGTTC CCAAAACCAT CCAGATGGTG
CGGTCTCAGA GGTCAGGGAT GGTCCAGACA GAAGCACAGT ACCGATTTAT CTATATGGCG
GTCCAGCATT ATATTGAAAC ACTACAGCGC AGGATTGAAG AAGAGCAGAA AAGCAAGAGG
AAAGGGCACG AATATACAAA TATTAAGTAT TCTCTAGCGG ACCAGACGAG TGGAGATCAG
AGCCCTCTCC CGCCTTGTAC TCCAACGCCA CCCTGTGCAG AAATGAGAGA AGACAGTGCT
AGAGTCTATG AAAACGTGGG CCTGATGCAA CAGCAGAAAA GTTTCAGATG A

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq XP_011536915.1
CDS201..1991
Misc Feature(1)213..506(+)
Misc Feature(2)237..362(+)
Misc Feature(3)351..476(+)
Misc Feature(4)528..851(+)
Misc Feature(5)612..638(+)
Misc Feature(6)705..788(+)
Misc Feature(7)933..1769(+)
Misc Feature(8)1023..1766(+)
Misc Feature(9)1482..1607(+)
Translation

Target ORF information:

RefSeq Version XM_011538613
Organism Homo sapiens (human)
Definition PREDICTED: Homo sapiens protein tyrosine phosphatase, non-receptor type 11 (PTPN11), transcript variant X2, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
XM_011538613

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
1501
1561
1621
1681
1741
ATGACATCGC GGAGATGGTT TCACCCAAAT ATCACTGGTG TGGAGGCAGA AAACCTACTG 
TTGACAAGAG GAGTTGATGG CAGTTTTTTG GCAAGGCCTA GTAAAAGTAA CCCTGGAGAC
TTCACACTTT CCGTTAGAAA TGGAGCTGTC ACCCACATCA AGATTCAGAA CACTGGTGAT
TACTATGACC TGTATGGAGG GGAGAAATTT GCCACTTTGG CTGAGTTGGT CCAGTATTAC
ATGGAACATC ACGGGCAATT AAAAGAGAAG AATGGAGATG TCATTGAGCT TAAATATCCT
CTGAACTGTG CAGATCCTAC CTCTGAAAGG TGGTTTCATG GACATCTCTC TGGGAAAGAA
GCAGAGAAAT TATTAACTGA AAAAGGAAAA CATGGTAGTT TTCTTGTACG AGAGAGCCAG
AGCCACCCTG GAGATTTTGT TCTTTCTGTG CGCACTGGTG ATGACAAAGG GGAGAGCAAT
GACGGCAAGT CTAAAGTGAC CCATGTTATG ATTCGCTGTC AGGAACTGAA ATACGACGTT
GGTGGAGGAG AACGGTTTGA TTCTTTGACA GATCTTGTGG AACATTATAA GAAGAATCCT
ATGGTGGAAA CATTGGGTAC AGTACTACAA CTCAAGCAGC CCCTTAACAC GACTCGTATA
AATGCTGCTG AAATAGAAAG CAGAGTTCGA GAACTAAGCA AATTAGCTGA GACCACAGAT
AAAGTCAAAC AAGGCTTTTG GGAAGAATTT GAGACACTAC AACAACAGGA GTGCAAACTT
CTCTACAGCC GAAAAGAGGG TCAAAGGCAA GAAAACAAAA ACAAAAATAG ATATAAAAAC
ATCCTGCCCT TTGATCATAC CAGGGTTGTC CTACACGATG GTGATCCCAA TGAGCCTGTT
TCAGATTACA TCAATGCAAA TATCATCATG CCTGAATTTG AAACCAAGTG CAACAATTCA
AAGCCCAAAA AGAGTTACAT TGCCACACAA GGCTGCCTGC AAAACACGGT GAATGACTTT
TGGCGGATGG TGTTCCAAGA AAACTCCCGA GTGATTGTCA TGACAACGAA AGAAGTGGAG
AGAGGAAAGA GTAAATGTGT CAAATACTGG CCTGATGAGT ATGCTCTAAA AGAATATGGC
GTCATGCGTG TTAGGAACGT CAAAGAAAGC GCCGCTCATG ACTATACGCT AAGAGAACTT
AAACTTTCAA AGGTTGGACA AGCTCTACTC CAGGGGAATA CGGAGAGAAC GGTCTGGCAA
TACCACTTTC GGACCTGGCC GGACCACGGC GTGCCCAGCG ACCCTGGGGG CGTGCTGGAC
TTCCTGGAGG AGGTGCACCA TAAGCAGGAG AGCATCATGG ATGCAGGGCC GGTCGTGGTG
CACTGCAGTG CTGGAATTGG CCGGACAGGG ACGTTCATTG TGATTGATAT TCTTATTGAC
ATCATCAGAG AGAAAGGTGT TGACTGCGAT ATTGACGTTC CCAAAACCAT CCAGATGGTG
CGGTCTCAGA GGTCAGGGAT GGTCCAGACA GAAGCACAGT ACCGATTTAT CTATATGGCG
GTCCAGCATT ATATTGAAAC ACTACAGCGC AGGATTGAAG AAGAGCAGAA AAGCAAGAGG
AAAGGGCACG AATATACAAA TATTAAGTAT TCTCTAGCGG ACCAGACGAG TGGAGATCAG
AGCCCTCTCC CGCCTTGTAC TCCAACGCCA CCCTGTGCAG AAATGAGAGA AGACAGTGCT
AGAGTCTATG AAAACGTGGG CCTGATGCAA CAGCAGAAAA GTTTCAGATG A

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OHu46741
Clone ID Related Accession (Same CDS sequence) XM_006719527
Accession Version XM_006719527.1 Documents for ORF clone product in dufault vector
Sequence Information ORF Nucleotide Sequence (Length: 1680bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ® Seamless cloning technology
Insert Structure linear
Update Date 12-MAR-2015
Organism Homo sapiens (human)
Product tyrosine-protein phosphatase non-receptor type 11 isoform X3
Comment MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NT_029419.13) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Homo sapiens Annotation Release 107 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 6.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
1501
1561
1621
ATGACATCGC GGAGATGGTT TCACCCAAAT ATCACTGGTG TGGAGGCAGA AAACCTACTG 
TTGACAAGAG GAGTTGATGG CAGTTTTTTG GCAAGGCCTA GTAAAAGTAA CCCTGGAGAC
TTCACACTTT CCGTTAGAAG AAATGGAGCT GTCACCCACA TCAAGATTCA GAACACTGGT
GATTACTATG ACCTGTATGG AGGGGAGAAA TTTGCCACTT TGGCTGAGTT GGTCCAGTAT
TACATGGAAC ATCACGGGCA ATTAAAAGAG AAGAATGGAG ATGTCATTGA GCTTAAATAT
CCTCTGAACT GTGCAGATCC TACCTCTGAA AGGTGGTTTC ATGGACATCT CTCTGGGAAA
GAAGCAGAGA AATTATTAAC TGAAAAAGGA AAACATGGTA GTTTTCTTGT ACGAGAGAGC
CAGAGCCACC CTGGAGATTT TGTTCTTTCT GTGCGCACTG GTGATGACAA AGGGGAGAGC
AATGACGGCA AGTCTAAAGT GACCCATGTT ATGATTCGCT GTCAGGAACT GAAATACGAC
GTTGGTGGAG GAGAACGGTT TGATTCTTTG ACAGATCTTG TGGAACATTA TAAGAAGAAT
CCTATGGTGG AAACATTGGG TACAGTACTA CAACTCAAGC AGACACTACA ACAACAGGAG
TGCAAACTTC TCTACAGCCG AAAAGAGGGT CAAAGGCAAG AAAACAAAAA CAAAAATAGA
TATAAAAACA TCCTGCCCTT TGATCATACC AGGGTTGTCC TACACGATGG TGATCCCAAT
GAGCCTGTTT CAGATTACAT CAATGCAAAT ATCATCATGC CTGAATTTGA AACCAAGTGC
AACAATTCAA AGCCCAAAAA GAGTTACATT GCCACACAAG GCTGCCTGCA AAACACGGTG
AATGACTTTT GGCGGATGGT GTTCCAAGAA AACTCCCGAG TGATTGTCAT GACAACGAAA
GAAGTGGAGA GAGGAAAGAG TAAATGTGTC AAATACTGGC CTGATGAGTA TGCTCTAAAA
GAATATGGCG TCATGCGTGT TAGGAACGTC AAAGAAAGCG CCGCTCATGA CTATACGCTA
AGAGAACTTA AACTTTCAAA GGTTGGACAA GCTCTACTCC AGGGGAATAC GGAGAGAACG
GTCTGGCAAT ACCACTTTCG GACCTGGCCG GACCACGGCG TGCCCAGCGA CCCTGGGGGC
GTGCTGGACT TCCTGGAGGA GGTGCACCAT AAGCAGGAGA GCATCATGGA TGCAGGGCCG
GTCGTGGTGC ACTGCAGTGC TGGAATTGGC CGGACAGGGA CGTTCATTGT GATTGATATT
CTTATTGACA TCATCAGAGA GAAAGGTGTT GACTGCGATA TTGACGTTCC CAAAACCATC
CAGATGGTGC GGTCTCAGAG GTCAGGGATG GTCCAGACAG AAGCACAGTA CCGATTTATC
TATATGGCGG TCCAGCATTA TATTGAAACA CTACAGCGCA GGATTGAAGA AGAGCAGAAA
AGCAAGAGGA AAGGGCACGA ATATACAAAT ATTAAGTATT CTCTAGCGGA CCAGACGAGT
GGAGATCAGA GCCCTCTCCC GCCTTGTACT CCAACGCCAC CCTGTGCAGA AATGAGAGAA
GACAGTGCTA GAGTCTATGA AAACGTGGGC CTGATGCAAC AGCAGAAAAG TTTCAGATGA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq XP_006719590.1
CDS166..1845
Misc Feature(1)178..474(+)
Misc Feature(2)202..330(+)
Misc Feature(3)319..444(+)
Misc Feature(4)496..792(+)
Misc Feature(5)580..606(+)
Misc Feature(6)673..756(+)
Misc Feature(7)841..1623(+)
Misc Feature(8)877..1620(+)
Misc Feature(9)1336..1461(+)
Translation

Target ORF information:

RefSeq Version XM_006719527
Organism Homo sapiens (human)
Definition PREDICTED: Homo sapiens protein tyrosine phosphatase, non-receptor type 11 (PTPN11), transcript variant X3, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
XM_006719527

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
1501
1561
1621
ATGACATCGC GGAGATGGTT TCACCCAAAT ATCACTGGTG TGGAGGCAGA AAACCTACTG 
TTGACAAGAG GAGTTGATGG CAGTTTTTTG GCAAGGCCTA GTAAAAGTAA CCCTGGAGAC
TTCACACTTT CCGTTAGAAG AAATGGAGCT GTCACCCACA TCAAGATTCA GAACACTGGT
GATTACTATG ACCTGTATGG AGGGGAGAAA TTTGCCACTT TGGCTGAGTT GGTCCAGTAT
TACATGGAAC ATCACGGGCA ATTAAAAGAG AAGAATGGAG ATGTCATTGA GCTTAAATAT
CCTCTGAACT GTGCAGATCC TACCTCTGAA AGGTGGTTTC ATGGACATCT CTCTGGGAAA
GAAGCAGAGA AATTATTAAC TGAAAAAGGA AAACATGGTA GTTTTCTTGT ACGAGAGAGC
CAGAGCCACC CTGGAGATTT TGTTCTTTCT GTGCGCACTG GTGATGACAA AGGGGAGAGC
AATGACGGCA AGTCTAAAGT GACCCATGTT ATGATTCGCT GTCAGGAACT GAAATACGAC
GTTGGTGGAG GAGAACGGTT TGATTCTTTG ACAGATCTTG TGGAACATTA TAAGAAGAAT
CCTATGGTGG AAACATTGGG TACAGTACTA CAACTCAAGC AGACACTACA ACAACAGGAG
TGCAAACTTC TCTACAGCCG AAAAGAGGGT CAAAGGCAAG AAAACAAAAA CAAAAATAGA
TATAAAAACA TCCTGCCCTT TGATCATACC AGGGTTGTCC TACACGATGG TGATCCCAAT
GAGCCTGTTT CAGATTACAT CAATGCAAAT ATCATCATGC CTGAATTTGA AACCAAGTGC
AACAATTCAA AGCCCAAAAA GAGTTACATT GCCACACAAG GCTGCCTGCA AAACACGGTG
AATGACTTTT GGCGGATGGT GTTCCAAGAA AACTCCCGAG TGATTGTCAT GACAACGAAA
GAAGTGGAGA GAGGAAAGAG TAAATGTGTC AAATACTGGC CTGATGAGTA TGCTCTAAAA
GAATATGGCG TCATGCGTGT TAGGAACGTC AAAGAAAGCG CCGCTCATGA CTATACGCTA
AGAGAACTTA AACTTTCAAA GGTTGGACAA GCTCTACTCC AGGGGAATAC GGAGAGAACG
GTCTGGCAAT ACCACTTTCG GACCTGGCCG GACCACGGCG TGCCCAGCGA CCCTGGGGGC
GTGCTGGACT TCCTGGAGGA GGTGCACCAT AAGCAGGAGA GCATCATGGA TGCAGGGCCG
GTCGTGGTGC ACTGCAGTGC TGGAATTGGC CGGACAGGGA CGTTCATTGT GATTGATATT
CTTATTGACA TCATCAGAGA GAAAGGTGTT GACTGCGATA TTGACGTTCC CAAAACCATC
CAGATGGTGC GGTCTCAGAG GTCAGGGATG GTCCAGACAG AAGCACAGTA CCGATTTATC
TATATGGCGG TCCAGCATTA TATTGAAACA CTACAGCGCA GGATTGAAGA AGAGCAGAAA
AGCAAGAGGA AAGGGCACGA ATATACAAAT ATTAAGTATT CTCTAGCGGA CCAGACGAGT
GGAGATCAGA GCCCTCTCCC GCCTTGTACT CCAACGCCAC CCTGTGCAGA AATGAGAGAA
GACAGTGCTA GAGTCTATGA AAACGTGGGC CTGATGCAAC AGCAGAAAAG TTTCAGATGA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OHu25096
Clone ID Related Accession (Same CDS sequence) NM_002834
Accession Version NM_002834.3 Documents for ORF clone product in dufault vector
Sequence Information ORF Nucleotide Sequence (Length: 1782bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags COA
ORF Insert Method CloneEZ® Seamless cloning technology
Insert Structure linear
Update Date 15-MAR-2015
Organism Homo sapiens (human)
Product tyrosine-protein phosphatase non-receptor type 11 isoform 1
Comment REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from BF515187.1, AK289854.1, CN258646.1, BX537632.1 and AC004216.1. This sequence is a reference standard in the RefSeqGene project. On or before Jul 31, 2003 this sequence version replaced gi:14249675, gi:18375641. Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (1). Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: D13540.1, L08807.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
1501
1561
1621
1681
1741
ATGACATCGC GGAGATGGTT TCACCCAAAT ATCACTGGTG TGGAGGCAGA AAACCTACTG 
TTGACAAGAG GAGTTGATGG CAGTTTTTTG GCAAGGCCTA GTAAAAGTAA CCCTGGAGAC
TTCACACTTT CCGTTAGAAG AAATGGAGCT GTCACCCACA TCAAGATTCA GAACACTGGT
GATTACTATG ACCTGTATGG AGGGGAGAAA TTTGCCACTT TGGCTGAGTT GGTCCAGTAT
TACATGGAAC ATCACGGGCA ATTAAAAGAG AAGAATGGAG ATGTCATTGA GCTTAAATAT
CCTCTGAACT GTGCAGATCC TACCTCTGAA AGGTGGTTTC ATGGACATCT CTCTGGGAAA
GAAGCAGAGA AATTATTAAC TGAAAAAGGA AAACATGGTA GTTTTCTTGT ACGAGAGAGC
CAGAGCCACC CTGGAGATTT TGTTCTTTCT GTGCGCACTG GTGATGACAA AGGGGAGAGC
AATGACGGCA AGTCTAAAGT GACCCATGTT ATGATTCGCT GTCAGGAACT GAAATACGAC
GTTGGTGGAG GAGAACGGTT TGATTCTTTG ACAGATCTTG TGGAACATTA TAAGAAGAAT
CCTATGGTGG AAACATTGGG TACAGTACTA CAACTCAAGC AGCCCCTTAA CACGACTCGT
ATAAATGCTG CTGAAATAGA AAGCAGAGTT CGAGAACTAA GCAAATTAGC TGAGACCACA
GATAAAGTCA AACAAGGCTT TTGGGAAGAA TTTGAGACAC TACAACAACA GGAGTGCAAA
CTTCTCTACA GCCGAAAAGA GGGTCAAAGG CAAGAAAACA AAAACAAAAA TAGATATAAA
AACATCCTGC CCTTTGATCA TACCAGGGTT GTCCTACACG ATGGTGATCC CAATGAGCCT
GTTTCAGATT ACATCAATGC AAATATCATC ATGCCTGAAT TTGAAACCAA GTGCAACAAT
TCAAAGCCCA AAAAGAGTTA CATTGCCACA CAAGGCTGCC TGCAAAACAC GGTGAATGAC
TTTTGGCGGA TGGTGTTCCA AGAAAACTCC CGAGTGATTG TCATGACAAC GAAAGAAGTG
GAGAGAGGAA AGAGTAAATG TGTCAAATAC TGGCCTGATG AGTATGCTCT AAAAGAATAT
GGCGTCATGC GTGTTAGGAA CGTCAAAGAA AGCGCCGCTC ATGACTATAC GCTAAGAGAA
CTTAAACTTT CAAAGGTTGG ACAAGGGAAT ACGGAGAGAA CGGTCTGGCA ATACCACTTT
CGGACCTGGC CGGACCACGG CGTGCCCAGC GACCCTGGGG GCGTGCTGGA CTTCCTGGAG
GAGGTGCACC ATAAGCAGGA GAGCATCATG GATGCAGGGC CGGTCGTGGT GCACTGCAGT
GCTGGAATTG GCCGGACAGG GACGTTCATT GTGATTGATA TTCTTATTGA CATCATCAGA
GAGAAAGGTG TTGACTGCGA TATTGACGTT CCCAAAACCA TCCAGATGGT GCGGTCTCAG
AGGTCAGGGA TGGTCCAGAC AGAAGCACAG TACCGATTTA TCTATATGGC GGTCCAGCAT
TATATTGAAA CACTACAGCG CAGGATTGAA GAAGAGCAGA AAAGCAAGAG GAAAGGGCAC
GAATATACAA ATATTAAGTA TTCTCTAGCG GACCAGACGA GTGGAGATCA GAGCCCTCTC
CCGCCTTGTA CTCCAACGCC ACCCTGTGCA GAAATGAGAG AAGACAGTGC TAGAGTCTAT
GAAAACGTGG GCCTGATGCA ACAGCAGAAA AGTTTCAGAT GA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq NP_002825.3
CDS381..2162
Misc Feature(1)336..338(+)
Misc Feature(2)384..386(+)
Misc Feature(3)393..689(+)
Misc Feature(4)417..545(+)
Misc Feature(5)534..659(+)
Misc Feature(6)564..566(+)
Misc Feature(7)564..566(+)
Misc Feature(8)567..569(+)
Misc Feature(9)567..569(+)
Misc Feature(10)711..1034(+)
Misc Feature(11)795..821(+)
Misc Feature(12)888..971(+)
Misc Feature(13)1116..1940(+)
Misc Feature(14)1206..1937(+)
Misc Feature(15)1653..1778(+)
Misc Feature(16)1755..1775(+)
Misc Feature(17)2004..2006(+)
Misc Feature(18)2004..2006(+)
Misc Feature(19)2052..2054(+)
Misc Feature(20)2106..2108(+)
Misc Feature(21)2106..2108(+)
Misc Feature(22)2106..2108(+)
Misc Feature(23)2118..2120(+)
Misc Feature(24)2118..2120(+)
Misc Feature(25)2151..2153(+)
Exon (1)1..394
Gene:PTPN11
Gene Synonym:
Exon (2)395..517
Gene:PTPN11
Gene Synonym:
Exon (3)518..712
Gene:PTPN11
Gene Synonym:
Exon (4)713..905
Gene:PTPN11
Gene Synonym:
Exon (5)906..1022
Gene:PTPN11
Gene Synonym:
Exon (6)1023..1136
Gene:PTPN11
Gene Synonym:
Exon (7)1137..1233
Gene:PTPN11
Gene Synonym:
Exon (8)1234..1313
Gene:PTPN11
Gene Synonym:
Exon (9)1314..1472
Gene:PTPN11
Gene Synonym:
Exon (10)1473..1604
Gene:PTPN11
Gene Synonym:
Exon (11)1605..1759
Gene:PTPN11
Gene Synonym:
Exon (12)1760..1827
Gene:PTPN11
Gene Synonym:
Exon (13)1828..1979
Gene:PTPN11
Gene Synonym:
Exon (14)1980..2092
Gene:PTPN11
Gene Synonym:
Exon (15)2093..2194
Gene:PTPN11
Gene Synonym:
Exon (16)2195..6283
Gene:PTPN11
Gene Synonym:
Translation

Target ORF information:

RefSeq Version NM_002834
Organism Homo sapiens (human)
Definition Homo sapiens protein tyrosine phosphatase, non-receptor type 11 (PTPN11), transcript variant 1, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
NM_002834

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
1501
1561
1621
1681
1741
ATGACATCGC GGAGATGGTT TCACCCAAAT ATCACTGGTG TGGAGGCAGA AAACCTACTG 
TTGACAAGAG GAGTTGATGG CAGTTTTTTG GCAAGGCCTA GTAAAAGTAA CCCTGGAGAC
TTCACACTTT CCGTTAGAAG AAATGGAGCT GTCACCCACA TCAAGATTCA GAACACTGGT
GATTACTATG ACCTGTATGG AGGGGAGAAA TTTGCCACTT TGGCTGAGTT GGTCCAGTAT
TACATGGAAC ATCACGGGCA ATTAAAAGAG AAGAATGGAG ATGTCATTGA GCTTAAATAT
CCTCTGAACT GTGCAGATCC TACCTCTGAA AGGTGGTTTC ATGGACATCT CTCTGGGAAA
GAAGCAGAGA AATTATTAAC TGAAAAAGGA AAACATGGTA GTTTTCTTGT ACGAGAGAGC
CAGAGCCACC CTGGAGATTT TGTTCTTTCT GTGCGCACTG GTGATGACAA AGGGGAGAGC
AATGACGGCA AGTCTAAAGT GACCCATGTT ATGATTCGCT GTCAGGAACT GAAATACGAC
GTTGGTGGAG GAGAACGGTT TGATTCTTTG ACAGATCTTG TGGAACATTA TAAGAAGAAT
CCTATGGTGG AAACATTGGG TACAGTACTA CAACTCAAGC AGCCCCTTAA CACGACTCGT
ATAAATGCTG CTGAAATAGA AAGCAGAGTT CGAGAACTAA GCAAATTAGC TGAGACCACA
GATAAAGTCA AACAAGGCTT TTGGGAAGAA TTTGAGACAC TACAACAACA GGAGTGCAAA
CTTCTCTACA GCCGAAAAGA GGGTCAAAGG CAAGAAAACA AAAACAAAAA TAGATATAAA
AACATCCTGC CCTTTGATCA TACCAGGGTT GTCCTACACG ATGGTGATCC CAATGAGCCT
GTTTCAGATT ACATCAATGC AAATATCATC ATGCCTGAAT TTGAAACCAA GTGCAACAAT
TCAAAGCCCA AAAAGAGTTA CATTGCCACA CAAGGCTGCC TGCAAAACAC GGTGAATGAC
TTTTGGCGGA TGGTGTTCCA AGAAAACTCC CGAGTGATTG TCATGACAAC GAAAGAAGTG
GAGAGAGGAA AGAGTAAATG TGTCAAATAC TGGCCTGATG AGTATGCTCT AAAAGAATAT
GGCGTCATGC GTGTTAGGAA CGTCAAAGAA AGCGCCGCTC ATGACTATAC GCTAAGAGAA
CTTAAACTTT CAAAGGTTGG ACAAGGGAAT ACGGAGAGAA CGGTCTGGCA ATACCACTTT
CGGACCTGGC CGGACCACGG CGTGCCCAGC GACCCTGGGG GCGTGCTGGA CTTCCTGGAG
GAGGTGCACC ATAAGCAGGA GAGCATCATG GATGCAGGGC CGGTCGTGGT GCACTGCAGT
GCTGGAATTG GCCGGACAGG GACGTTCATT GTGATTGATA TTCTTATTGA CATCATCAGA
GAGAAAGGTG TTGACTGCGA TATTGACGTT CCCAAAACCA TCCAGATGGT GCGGTCTCAG
AGGTCAGGGA TGGTCCAGAC AGAAGCACAG TACCGATTTA TCTATATGGC GGTCCAGCAT
TATATTGAAA CACTACAGCG CAGGATTGAA GAAGAGCAGA AAAGCAAGAG GAAAGGGCAC
GAATATACAA ATATTAAGTA TTCTCTAGCG GACCAGACGA GTGGAGATCA GAGCCCTCTC
CCGCCTTGTA CTCCAACGCC ACCCTGTGCA GAAATGAGAG AAGACAGTGC TAGAGTCTAT
GAAAACGTGG GCCTGATGCA ACAGCAGAAA AGTTTCAGAT GA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OHu24957
Clone ID Related Accession (Same CDS sequence) NM_080601
Accession Version NM_080601.1 Documents for ORF clone product in dufault vector
Sequence Information ORF Nucleotide Sequence (Length: 1383bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags COA
ORF Insert Method CloneEZ® Seamless cloning technology
Insert Structure linear
Update Date 15-MAR-2015
Organism Homo sapiens (human)
Product tyrosine-protein phosphatase non-receptor type 11 isoform 2
Comment REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from BF515187.1 and BC008692.1. Transcript Variant: This variant (2) differs in the 3' UTR and coding sequence compared to variant 1. The resulting isoform (2) has a shorter and distinct N-terminus compared to isoform 1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC008692.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
ATGACATCGC GGAGATGGTT TCACCCAAAT ATCACTGGTG TGGAGGCAGA AAACCTACTG 
TTGACAAGAG GAGTTGATGG CAGTTTTTTG GCAAGGCCTA GTAAAAGTAA CCCTGGAGAC
TTCACACTTT CCGTTAGAAG AAATGGAGCT GTCACCCACA TCAAGATTCA GAACACTGGT
GATTACTATG ACCTGTATGG AGGGGAGAAA TTTGCCACTT TGGCTGAGTT GGTCCAGTAT
TACATGGAAC ATCACGGGCA ATTAAAAGAG AAGAATGGAG ATGTCATTGA GCTTAAATAT
CCTCTGAACT GTGCAGATCC TACCTCTGAA AGGTGGTTTC ATGGACATCT CTCTGGGAAA
GAAGCAGAGA AATTATTAAC TGAAAAAGGA AAACATGGTA GTTTTCTTGT ACGAGAGAGC
CAGAGCCACC CTGGAGATTT TGTTCTTTCT GTGCGCACTG GTGATGACAA AGGGGAGAGC
AATGACGGCA AGTCTAAAGT GACCCATGTT ATGATTCGCT GTCAGGAACT GAAATACGAC
GTTGGTGGAG GAGAACGGTT TGATTCTTTG ACAGATCTTG TGGAACATTA TAAGAAGAAT
CCTATGGTGG AAACATTGGG TACAGTACTA CAACTCAAGC AGCCCCTTAA CACGACTCGT
ATAAATGCTG CTGAAATAGA AAGCAGAGTT CGAGAACTAA GCAAATTAGC TGAGACCACA
GATAAAGTCA AACAAGGCTT TTGGGAAGAA TTTGAGACAC TACAACAACA GGAGTGCAAA
CTTCTCTACA GCCGAAAAGA GGGTCAAAGG CAAGAAAACA AAAACAAAAA TAGATATAAA
AACATCCTGC CCTTTGATCA TACCAGGGTT GTCCTACACG ATGGTGATCC CAATGAGCCT
GTTTCAGATT ACATCAATGC AAATATCATC ATGCCTGAAT TTGAAACCAA GTGCAACAAT
TCAAAGCCCA AAAAGAGTTA CATTGCCACA CAAGGCTGCC TGCAAAACAC GGTGAATGAC
TTTTGGCGGA TGGTGTTCCA AGAAAACTCC CGAGTGATTG TCATGACAAC GAAAGAAGTG
GAGAGAGGAA AGAGTAAATG TGTCAAATAC TGGCCTGATG AGTATGCTCT AAAAGAATAT
GGCGTCATGC GTGTTAGGAA CGTCAAAGAA AGCGCCGCTC ATGACTATAC GCTAAGAGAA
CTTAAACTTT CAAAGGTTGG ACAAGGGAAT ACGGAGAGAA CGGTCTGGCA ATACCACTTT
CGGACCTGGC CGGACCACGG CGTGCCCAGC GACCCTGGGG GCGTGCTGGA CTTCCTGGAG
GAGGTGCACC ATAAGCAGGA GAGCATCATG GATGCAGGGC CGGTCGTGGT GCACTGCAGG
TGA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq NP_542168.1
CDS381..1763
Misc Feature(1)336..338(+)
Misc Feature(2)384..386(+)
Misc Feature(3)393..689(+)
Misc Feature(4)417..545(+)
Misc Feature(5)534..659(+)
Misc Feature(6)564..566(+)
Misc Feature(7)567..569(+)
Misc Feature(8)711..1034(+)
Misc Feature(9)795..821(+)
Misc Feature(10)888..971(+)
Misc Feature(11)1116..>1757(+)
Misc Feature(12)1206..>1757(+)
Misc Feature(13)1653..1757(+)
Exon (1)1..394
Gene:PTPN11
Gene Synonym:
Exon (2)395..517
Gene:PTPN11
Gene Synonym:
Exon (3)518..712
Gene:PTPN11
Gene Synonym:
Exon (4)713..905
Gene:PTPN11
Gene Synonym:
Exon (5)906..1022
Gene:PTPN11
Gene Synonym:
Exon (6)1023..1136
Gene:PTPN11
Gene Synonym:
Exon (7)1137..1233
Gene:PTPN11
Gene Synonym:
Exon (8)1234..1313
Gene:PTPN11
Gene Synonym:
Exon (9)1314..1472
Gene:PTPN11
Gene Synonym:
Exon (10)1473..1604
Gene:PTPN11
Gene Synonym:
Exon (11)1605..2053
Gene:PTPN11
Gene Synonym:
Translation

Target ORF information:

RefSeq Version NM_080601
Organism Homo sapiens (human)
Definition Homo sapiens protein tyrosine phosphatase, non-receptor type 11 (PTPN11), transcript variant 2, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
NM_080601

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
ATGACATCGC GGAGATGGTT TCACCCAAAT ATCACTGGTG TGGAGGCAGA AAACCTACTG 
TTGACAAGAG GAGTTGATGG CAGTTTTTTG GCAAGGCCTA GTAAAAGTAA CCCTGGAGAC
TTCACACTTT CCGTTAGAAG AAATGGAGCT GTCACCCACA TCAAGATTCA GAACACTGGT
GATTACTATG ACCTGTATGG AGGGGAGAAA TTTGCCACTT TGGCTGAGTT GGTCCAGTAT
TACATGGAAC ATCACGGGCA ATTAAAAGAG AAGAATGGAG ATGTCATTGA GCTTAAATAT
CCTCTGAACT GTGCAGATCC TACCTCTGAA AGGTGGTTTC ATGGACATCT CTCTGGGAAA
GAAGCAGAGA AATTATTAAC TGAAAAAGGA AAACATGGTA GTTTTCTTGT ACGAGAGAGC
CAGAGCCACC CTGGAGATTT TGTTCTTTCT GTGCGCACTG GTGATGACAA AGGGGAGAGC
AATGACGGCA AGTCTAAAGT GACCCATGTT ATGATTCGCT GTCAGGAACT GAAATACGAC
GTTGGTGGAG GAGAACGGTT TGATTCTTTG ACAGATCTTG TGGAACATTA TAAGAAGAAT
CCTATGGTGG AAACATTGGG TACAGTACTA CAACTCAAGC AGCCCCTTAA CACGACTCGT
ATAAATGCTG CTGAAATAGA AAGCAGAGTT CGAGAACTAA GCAAATTAGC TGAGACCACA
GATAAAGTCA AACAAGGCTT TTGGGAAGAA TTTGAGACAC TACAACAACA GGAGTGCAAA
CTTCTCTACA GCCGAAAAGA GGGTCAAAGG CAAGAAAACA AAAACAAAAA TAGATATAAA
AACATCCTGC CCTTTGATCA TACCAGGGTT GTCCTACACG ATGGTGATCC CAATGAGCCT
GTTTCAGATT ACATCAATGC AAATATCATC ATGCCTGAAT TTGAAACCAA GTGCAACAAT
TCAAAGCCCA AAAAGAGTTA CATTGCCACA CAAGGCTGCC TGCAAAACAC GGTGAATGAC
TTTTGGCGGA TGGTGTTCCA AGAAAACTCC CGAGTGATTG TCATGACAAC GAAAGAAGTG
GAGAGAGGAA AGAGTAAATG TGTCAAATAC TGGCCTGATG AGTATGCTCT AAAAGAATAT
GGCGTCATGC GTGTTAGGAA CGTCAAAGAA AGCGCCGCTC ATGACTATAC GCTAAGAGAA
CTTAAACTTT CAAAGGTTGG ACAAGGGAAT ACGGAGAGAA CGGTCTGGCA ATACCACTTT
CGGACCTGGC CGGACCACGG CGTGCCCAGC GACCCTGGGG GCGTGCTGGA CTTCCTGGAG
GAGGTGCACC ATAAGCAGGA GAGCATCATG GATGCAGGGC CGGTCGTGGT GCACTGCAGG
TGA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

 
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