Gene Symbol | PLEKHB1 |
Entrez Gene ID | 58473 |
Full Name | pleckstrin homology domain containing B1 |
Synonyms | KPL1,PHR1,PHRET1 |
General protein information |
|
Gene Type | protein-coding |
Organism | Homo sapiens(human) |
Genome | |
Disorder MIM: |
ORF » Species Summary » Homo sapiens » PLEKHB1 cDNA ORF clone
Gene Symbol | PLEKHB1 |
Entrez Gene ID | 58473 |
Full Name | pleckstrin homology domain containing B1 |
Synonyms | KPL1,PHR1,PHRET1 |
General protein information |
|
Gene Type | protein-coding |
Organism | Homo sapiens(human) |
Genome | |
Disorder MIM: |
mRNA | Protein | Name |
---|---|---|
NM_001130033.1 | NP_001123505.1 | pleckstrin homology domain-containing family B member 1 isoform c |
NM_001130034.1 | NP_001123506.1 | pleckstrin homology domain-containing family B member 1 isoform b |
NM_001130035.1 | NP_001123507.1 | pleckstrin homology domain-containing family B member 1 isoform d |
NM_021200.3 | NP_067023.1 | pleckstrin homology domain-containing family B member 1 isoform a |
XM_011545193.1 | XP_011543495.1 | pleckstrin homology domain-containing family B member 1 isoform X2 |
NM_021200.2 | NP_067023.1 | pleckstrin homology domain-containing family B member 1 isoform a |
NM_001130035.2 | NP_001123507.1 | pleckstrin homology domain-containing family B member 1 isoform d |
NM_001130036.2 | NP_001123508.1 | pleckstrin homology domain-containing family B member 1 isoform d |
NM_001130036.1 | NP_001123508.1 | pleckstrin homology domain-containing family B member 1 isoform d |
NM_001130034.2 | NP_001123506.1 | pleckstrin homology domain-containing family B member 1 isoform b |
NM_001130033.2 | NP_001123505.1 | pleckstrin homology domain-containing family B member 1 isoform c |
XM_011545192.2 | XP_011543494.1 | pleckstrin homology domain-containing family B member 1 isoform X1 |
XM_011545193.2 | XP_011543495.1 | pleckstrin homology domain-containing family B member 1 isoform X2 |
Gallus gallus (chicken) | PLEKHB1 | NP_001012564.1 |
Homo sapiens (human) | PLEKHB1 | NP_067023.1 |
Pan troglodytes (chimpanzee) | PLEKHB1 | XP_001174830.1 |
Canis lupus familiaris (dog) | PLEKHB1 | XP_850310.1 |
Bos taurus (cattle) | PLEKHB1 | NP_001106751.1 |
Mus musculus (house mouse) | Plekhb1 | NP_038774.1 |
Rattus norvegicus (Norway rat) | Plekhb1 | NP_742030.1 |
In vitro interaction between coxsackievirus B3 VP1 protein and human pleckstrin homology domain retinal protein (PHR1).
Zhou Y, Zhang Z, Wang H, Xia Y, Li X, Yan Y, Zou W, Zeng L, Huang X
Virus genes51(2)182-9(2015 Oct)
Phospho-tyrosine dependent protein-protein interaction network.
Grossmann A, Benlasfer N, Birth P, Hegele A, Wachsmuth F, Apelt L, Stelzl U
Molecular systems biology11(3)794(2015 Mar)
The palmitoyl acyltransferase HIP14 shares a high proportion of interactors with huntingtin: implications for a role in the pathogenesis of Huntington's disease.
Butland SL, Sanders SS, Schmidt ME, Riechers SP, Lin DT, Martin DD, Vaid K, Graham RK, Singaraja RR, Wanker EE, Conibear E, Hayden MR
Human molecular genetics23(15)4142-60(2014 Aug)
Wallerian degeneration: an emerging axon death pathway linking injury and disease.
Conforti L, Gilley J, Coleman MP
Nature reviews. Neuroscience15(6)394-409(2014 Jun)
Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study.
Bailey SD, Xie C, Do R, Montpetit A, Diaz R, Mohan V, Keavney B, Yusuf S, Gerstein HC, Engert JC, Anand S,
Diabetes care33(10)2250-3(2010 Oct)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
The human PHR1, a PH domain-containing protein with low expression in the heart and high expression in the brain, interacts with coxsackievirus B3 VP1, a major structural protein of coxsackievirus B3.
Title: In vitro interaction between coxsackievirus B3 VP1 protein and human pleckstrin homology domain retinal protein (PHR1).
Rapid Wallerian degeneration requires the pro-degenerative molecules PHR1.
Title: Wallerian degeneration: an emerging axon death pathway linking injury and disease.
Observational study and genome-wide association study of gene-disease association. (HuGE Navigator)
Title: Genome-wide copy number variation analysis in attention-deficit/hyperactivity disorder: association with neuropeptide Y gene dosage in an extended pedigree.
Observational study of gene-disease association, gene-environment interaction, and pharmacogenomic / toxicogenomic. (HuGE Navigator)
Title: Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study.
Phr1 is widely and abundantly expressed throughout mature olfactory neurons and other primary sensory neurons, but its absence does not appear to affect olfactory morphology, regeneration, sensory function, or adaptation.
Title: PHR1 is a vesicle-bound protein abundantly expressed in mature olfactory neurons.
The following PLEKHB1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the PLEKHB1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
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CloneID | OHu06977 | |
Clone ID Related Accession (Same CDS sequence) | NM_001130035.1 , XM_011545193.1 , NM_001130035.2 , NM_001130036.2 , NM_001130036.1 , XM_011545193.2 | |
Accession Version | NM_001130035.1 | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 570bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2018-11-11 | |
Organism | Homo sapiens(human) | |
Product | pleckstrin homology domain-containing family B member 1 isoform d | |
Comment | Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from DC305763.1, BC008075.2 and CK819503.1. Transcript Variant: This variant (4) lacks an in-frame exon and includes an alternate exon in the 5' CDS and 5' UTR resulting in use of a downstream start codon, compared to variant 1. It encodes isoform d, which shorter than isoform a. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AF093249.1, SRR1803613.72956.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end. |
1 | ATGGCCCTGG TGAGGGGCGG CTGGCTGTGG AGACAGAGCT CCATCCTCCG CCGCTGGAAG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_001123507.1 |
CDS | 230..799 |
Translation |
Target ORF information:
Target ORF information:
|
NM_001130035.1 |
1 | ATGGCCCTGG TGAGGGGCGG CTGGCTGTGG AGACAGAGCT CCATCCTCCG CCGCTGGAAG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OHu06977 | |
Clone ID Related Accession (Same CDS sequence) | NM_001130035.1 , XM_011545193.1 , NM_001130035.2 , NM_001130036.2 , NM_001130036.1 , XM_011545193.2 | |
Accession Version | NM_001130035.2 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 570bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-10-25 | |
Organism | Homo sapiens(human) | |
Product | pleckstrin homology domain-containing family B member 1 isoform d | |
Comment | Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AP000860.4 and AP002993.3. On May 31, 2019 this sequence version replaced NM_001130035.1. Transcript Variant: This variant (4) lacks an in-frame exon and includes an alternate exon in the 5' CDS and 5' UTR resulting in use of a downstream start codon, compared to variant 1. It encodes isoform d, which shorter than isoform a. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: ERR279860.3800.1, AF093249.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end. |
1 | ATGGCCCTGG TGAGGGGCGG CTGGCTGTGG AGACAGAGCT CCATCCTCCG CCGCTGGAAG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_001123507.1 |
CDS | 125..694 |
Translation |
Target ORF information:
Target ORF information:
|
NM_001130035.2 |
1 | ATGGCCCTGG TGAGGGGCGG CTGGCTGTGG AGACAGAGCT CCATCCTCCG CCGCTGGAAG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OHu06977 | |
Clone ID Related Accession (Same CDS sequence) | NM_001130035.1 , XM_011545193.1 , NM_001130035.2 , NM_001130036.2 , NM_001130036.1 , XM_011545193.2 | |
Accession Version | NM_001130036.2 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 570bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-10-25 | |
Organism | Homo sapiens(human) | |
Product | pleckstrin homology domain-containing family B member 1 isoform d | |
Comment | Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AP000860.4 and AP002993.3. On May 31, 2019 this sequence version replaced NM_001130036.1. Transcript Variant: This variant (5) lacks an in-frame exon and includes an alternate exon in the 5' CDS and 5' UTR resulting in use of a downstream start codon, compared to variant 1. It encodes isoform d, which shorter than isoform a. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR3476690.74751.1, SRR1660805.215160.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end. |
1 | ATGGCCCTGG TGAGGGGCGG CTGGCTGTGG AGACAGAGCT CCATCCTCCG CCGCTGGAAG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_001123508.1 |
CDS | 139..708 |
Translation |
Target ORF information:
Target ORF information:
|
NM_001130036.2 |
1 | ATGGCCCTGG TGAGGGGCGG CTGGCTGTGG AGACAGAGCT CCATCCTCCG CCGCTGGAAG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OHu06977 | |
Clone ID Related Accession (Same CDS sequence) | NM_001130035.1 , XM_011545193.1 , NM_001130035.2 , NM_001130036.2 , NM_001130036.1 , XM_011545193.2 | |
Accession Version | NM_001130036.1 | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 570bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-02-17 | |
Organism | Homo sapiens(human) | |
Product | pleckstrin homology domain-containing family B member 1 isoform d | |
Comment | Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AK290109.1, EB387039.1, AL712105.1 and CK819503.1. Transcript Variant: This variant (5) lacks an in-frame exon and includes an alternate exon in the 5' CDS and 5' UTR resulting in use of a downstream start codon, compared to variant 1. It encodes isoform d, which shorter than isoform a. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AK290109.1, SRR1660805.215160.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end. |
1 | ATGGCCCTGG TGAGGGGCGG CTGGCTGTGG AGACAGAGCT CCATCCTCCG CCGCTGGAAG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_001123508.1 |
CDS | 362..931 |
Translation |
Target ORF information:
Target ORF information:
|
NM_001130036.1 |
1 | ATGGCCCTGG TGAGGGGCGG CTGGCTGTGG AGACAGAGCT CCATCCTCCG CCGCTGGAAG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OHu06977 | |
Clone ID Related Accession (Same CDS sequence) | NM_001130035.1 , XM_011545193.1 , NM_001130035.2 , NM_001130036.2 , NM_001130036.1 , XM_011545193.2 | |
Accession Version | XM_011545193.1 | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 570bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2015-03-11 | |
Organism | Homo sapiens(Human) | |
Product | pleckstrin homology domain-containing family B member 1 isoform X2 | |
Comment |
1 | ATGGCCCTGG TGAGGGGCGG CTGGCTGTGG AGACAGAGCT CCATCCTCCG CCGCTGGAAG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_011543495.1 |
Translation |
Target ORF information:
Target ORF information:
|
XM_011545193.1 |
1 | ATGGCCCTGG TGAGGGGCGG CTGGCTGTGG AGACAGAGCT CCATCCTCCG CCGCTGGAAG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OHu06977 | |
Clone ID Related Accession (Same CDS sequence) | NM_001130035.1 , XM_011545193.1 , NM_001130035.2 , NM_001130036.2 , NM_001130036.1 , XM_011545193.2 | |
Accession Version | XM_011545193.2 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 570bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-12-05 | |
Organism | Homo sapiens(human) | |
Product | pleckstrin homology domain-containing family B member 1 isoform X2 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000011.10) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 6, 2016 this sequence version replaced XM_011545193.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGGCCCTGG TGAGGGGCGG CTGGCTGTGG AGACAGAGCT CCATCCTCCG CCGCTGGAAG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_011543495.1 |
CDS | 1063..1632 |
Translation |
Target ORF information:
Target ORF information:
|
XM_011545193.2 |
1 | ATGGCCCTGG TGAGGGGCGG CTGGCTGTGG AGACAGAGCT CCATCCTCCG CCGCTGGAAG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OHu03684 | |
Clone ID Related Accession (Same CDS sequence) | NM_021200.3 , NM_021200.2 | |
Accession Version | NM_021200.3 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 732bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-10-25 | |
Organism | Homo sapiens(human) | |
Product | pleckstrin homology domain-containing family B member 1 isoform a | |
Comment | Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AP000860.4 and AP002993.3. On Nov 23, 2018 this sequence version replaced NM_021200.2. Transcript Variant: This variant (1) represents the longest transcript and encodes the longest isoform (a). Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: U89715.1, AK314748.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1968968, SAMEA2142586 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000354190.10/ ENSP00000346127.5 RefSeq Select criteria :: based on conservation, longest protein ##RefSeq-Attributes-END## COMPLETENESS: full length. |
1 | ATGAGCCCTG CAGCCCCGGT CCCGCCTGAC TCCGCTCTGG AAAGTCCTTT TGAAGAAATG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_067023.1 |
CDS | 29..760 |
Translation |
Target ORF information:
Target ORF information:
|
NM_021200.3 |
1 | ATGAGCCCTG CAGCCCCGGT CCCGCCTGAC TCCGCTCTGG AAAGTCCTTT TGAAGAAATG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OHu03684 | |
Clone ID Related Accession (Same CDS sequence) | NM_021200.3 , NM_021200.2 | |
Accession Version | NM_021200.2 | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 732bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2017-10-01 | |
Organism | Homo sapiens(human) | |
Product | pleckstrin homology domain-containing family B member 1 isoform a | |
Comment | Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AP000860.4, U89715.1 and CK819503.1. On Jul 11, 2008 this sequence version replaced NM_021200.1. Transcript Variant: This variant (1) represents the longest transcript and encodes the longest isoform (a). Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: U89715.1, AK314748.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1968968, SAMEA2142586 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end. |
1 | ATGAGCCCTG CAGCCCCGGT CCCGCCTGAC TCCGCTCTGG AAAGTCCTTT TGAAGAAATG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_067023.1 |
CDS | 432..1163 |
Translation |
Target ORF information:
Target ORF information:
|
NM_021200.2 |
1 | ATGAGCCCTG CAGCCCCGGT CCCGCCTGAC TCCGCTCTGG AAAGTCCTTT TGAAGAAATG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OHu06974 | |
Clone ID Related Accession (Same CDS sequence) | NM_001130033.1 , NM_001130033.2 | |
Accession Version | NM_001130033.1 | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 627bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-01-20 | |
Organism | Homo sapiens(human) | |
Product | pleckstrin homology domain-containing family B member 1 isoform c | |
Comment | Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AP000860.4, AF101054.1 and CK819503.1. Transcript Variant: This variant (3) lacks an in-frame exon, compared to variant 1. It encodes isoform c, which is shorter than isoform a. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AF101054.1, DB294414.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1968968, SAMEA2142586 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end. |
1 | ATGAGCCCTG CAGCCCCGGT CCCGCCTGAC TCCGCTCTGG AAAGTCCTTT TGAAGAAATG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_001123505.1 |
CDS | 432..1058 |
Translation |
Target ORF information:
Target ORF information:
|
NM_001130033.1 |
1 | ATGAGCCCTG CAGCCCCGGT CCCGCCTGAC TCCGCTCTGG AAAGTCCTTT TGAAGAAATG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OHu06974 | |
Clone ID Related Accession (Same CDS sequence) | NM_001130033.1 , NM_001130033.2 | |
Accession Version | NM_001130033.2 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 627bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-10-25 | |
Organism | Homo sapiens(human) | |
Product | pleckstrin homology domain-containing family B member 1 isoform c | |
Comment | Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AP000860.4 and AP002993.3. On May 31, 2019 this sequence version replaced NM_001130033.1. Transcript Variant: This variant (3) lacks an in-frame exon, compared to variant 1. It encodes isoform c, which is shorter than isoform a. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AF101054.1, DA367674.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1968968, SAMEA2142586 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end. |
1 | ATGAGCCCTG CAGCCCCGGT CCCGCCTGAC TCCGCTCTGG AAAGTCCTTT TGAAGAAATG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_001123505.1 |
CDS | 29..655 |
Translation |
Target ORF information:
Target ORF information:
|
NM_001130033.2 |
1 | ATGAGCCCTG CAGCCCCGGT CCCGCCTGAC TCCGCTCTGG AAAGTCCTTT TGAAGAAATG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OHu06975 | |
Clone ID Related Accession (Same CDS sequence) | NM_001130034.1 , NM_001130034.2 , XM_011545192.2 | |
Accession Version | NM_001130034.1 | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 675bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-01-20 | |
Organism | Homo sapiens(human) | |
Product | pleckstrin homology domain-containing family B member 1 isoform b | |
Comment | Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from DC305763.1, AF100612.1 and CK819503.1. Transcript Variant: This variant (2) includes an alternate exon in the 5' CDS and 5' UTR resulting in use of a downstream start codon, compared to variant 1. It encodes isoform b, which has a shorter N-terminus compared to isoform a. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AF100612.1, SRR1803616.18101.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1968832, SAMEA1968968 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end. |
1 | ATGGCCCTGG TGAGGGGCGG CTGGCTGTGG AGACAGAGCT CCATCCTCCG CCGCTGGAAG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_001123506.1 |
CDS | 230..904 |
Translation |
Target ORF information:
Target ORF information:
|
NM_001130034.1 |
1 | ATGGCCCTGG TGAGGGGCGG CTGGCTGTGG AGACAGAGCT CCATCCTCCG CCGCTGGAAG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OHu06975 | |
Clone ID Related Accession (Same CDS sequence) | NM_001130034.1 , NM_001130034.2 , XM_011545192.2 | |
Accession Version | NM_001130034.2 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 675bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-10-25 | |
Organism | Homo sapiens(human) | |
Product | pleckstrin homology domain-containing family B member 1 isoform b | |
Comment | Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AP000860.4 and AP002993.3. On May 31, 2019 this sequence version replaced NM_001130034.1. Transcript Variant: This variant (2) includes an alternate exon in the 5' CDS and 5' UTR resulting in use of a downstream start codon, compared to variant 1. It encodes isoform b, which has a shorter N-terminus compared to isoform a. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AF100612.1, DRR138524.18961.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1968832, SAMEA1968968 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end. |
1 | ATGGCCCTGG TGAGGGGCGG CTGGCTGTGG AGACAGAGCT CCATCCTCCG CCGCTGGAAG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_001123506.1 |
CDS | 125..799 |
Translation |
Target ORF information:
Target ORF information:
|
NM_001130034.2 |
1 | ATGGCCCTGG TGAGGGGCGG CTGGCTGTGG AGACAGAGCT CCATCCTCCG CCGCTGGAAG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OHu06975 | |
Clone ID Related Accession (Same CDS sequence) | NM_001130034.1 , NM_001130034.2 , XM_011545192.2 | |
Accession Version | XM_011545192.2 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 675bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-12-05 | |
Organism | Homo sapiens(human) | |
Product | pleckstrin homology domain-containing family B member 1 isoform X1 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000011.10) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 6, 2016 this sequence version replaced XM_011545192.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGGCCCTGG TGAGGGGCGG CTGGCTGTGG AGACAGAGCT CCATCCTCCG CCGCTGGAAG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_011543494.1 |
CDS | 1063..1737 |
Translation |
Target ORF information:
Target ORF information:
|
XM_011545192.2 |
1 | ATGGCCCTGG TGAGGGGCGG CTGGCTGTGG AGACAGAGCT CCATCCTCCG CCGCTGGAAG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
In vitro interaction between coxsackievirus B3 VP1 protein and human pleckstrin homology domain retinal protein (PHR1). |
Phospho-tyrosine dependent protein-protein interaction network. |
The palmitoyl acyltransferase HIP14 shares a high proportion of interactors with huntingtin: implications for a role in the pathogenesis of Huntington's disease. |
Wallerian degeneration: an emerging axon death pathway linking injury and disease. |
Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study. |