RBBP5 cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	RBBP5
Entrez Gene ID	5929
Full Name	RB binding protein 5, histone lysine methyltransferase complex subunit
Synonyms	RBQ3,SWD1
General protein information	Preferred Names RB binding protein 5, histone lysine methyltransferase complex subunit Names retinoblastoma-binding protein 5 RBBP-5 SWD1, Set1c WD40 repeat protein, homolog retinoblastoma-binding protein RBQ-3
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 1 Map Location: 1q32.1
Summary	This gene encodes a ubiquitously expressed nuclear protein which belongs to a highly conserved subfamily of WD-repeat proteins. The encoded protein binds directly to retinoblastoma protein, which regulates cell proliferation. It interacts preferentially with the underphosphorylated retinoblastoma protein via the E1A-binding pocket B. Three alternatively spliced transcript variants that encode different protein isoforms have been described for this gene. [provided by RefSeq, Jul 2010].
Disorder MIM:	600697

mRNA and Protein(s)

mRNA	Protein	Name
NM_001193272.1	NP_001180201.1	retinoblastoma-binding protein 5 isoform 2
NM_001193273.1	NP_001180202.1	retinoblastoma-binding protein 5 isoform 3
NM_005057.3	NP_005048.2	retinoblastoma-binding protein 5 isoform 1
NM_001193273.2	NP_001180202.1	retinoblastoma-binding protein 5 isoform 3
NM_001193272.2	NP_001180201.1	retinoblastoma-binding protein 5 isoform 2
XM_011509833.3	XP_011508135.1	retinoblastoma-binding protein 5 isoform X1
XM_011509833.2	XP_011508135.1	retinoblastoma-binding protein 5 isoform X1
NM_005057.4	NP_005048.2	retinoblastoma-binding protein 5 isoform 1

Pathways from BioSystems

Homologies

Eremothecium gossypii	AGOS_AFL006C	NP_985542.1
Schizosaccharomyces pombe (fission yeast)	swd1	NP_593795.1
Arabidopsis thaliana (thale cress)	AT3G21060	NP_188743.3
Danio rerio (zebrafish)	rbbp5	NP_956539.1
Kluyveromyces lactis	KLLA0A08800g	XP_451386.1
Oryza sativa (rice)	Os03g0207900	NP_001049328.1
Homo sapiens (human)	RBBP5	NP_005048.2
Canis lupus familiaris (dog)	RBBP5	XP_848552.1
Rattus norvegicus (Norway rat)	Rbbp5	NP_001100644.1
Gallus gallus (chicken)	RBBP5	NP_001026085.1
Drosophila melanogaster (fruit fly)	Rbbp5	NP_649209.1
Caenorhabditis elegans (roundworm)	F21H12.1	NP_495222.2
Saccharomyces cerevisiae (baker's yeast)	SWD1	NP_009403.1
Pan troglodytes (chimpanzee)	RBBP5	XP_514134.4
Bos taurus (cattle)	RBBP5	NP_001076871.1
Mus musculus (house mouse)	Rbbp5	NP_766105.2
Anopheles gambiae (African malaria mosquito)	AgaP_AGAP010575	XP_314543.3
Magnaporthe oryzae (rice blast fungus)	MGG_04651	XP_003713641.1
Neurospora crassa	NCU02104	XP_964098.1
Xenopus tropicalis (tropical clawed frog)	rbbp5	NP_001025680.1

Gene Ontology
Bibliography

Related articles in PubMed

Somatic cancer mutations in the MLL1 histone methyltransferase modulate its enzymatic activity and dependence on the WDR5/RBBP5/ASH2L complex.
Weirich S, Kudithipudi S, Jeltsch A
Molecular oncology11(4)373-387(2017 Apr)

A High-Density Map for Navigating the Human Polycomb Complexome.
Hauri S, Comoglio F, Seimiya M, Gerstung M, Glatter T, Hansen K, Aebersold R, Paro R, Gstaiger M, Beisel C
Cell reports17(2)583-595(2016 10)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

different cancer mutations in MLL1 lead to a loss or increase in activity, illustrating the complex and tumor-specific role of MLL1 in carcinogenesis.
Title: Somatic cancer mutations in the MLL1 histone methyltransferase modulate its enzymatic activity and dependence on the WDR5/RBBP5/ASH2L complex.

role of RBQ3 in the development of multiple myeloma
Title: RBQ3 participates in multiple myeloma cell proliferation, adhesion and chemoresistance.

This study demonstrated that RBQ3 might play an important role in glioma, and RBQ3 inhibitors might be novel anti-tumor agents.
Title: Expression and clinical role of RBQ3 in gliomas.

Non active site mutations in the MLL1 SET domain render the protein defective for H3K4 dimethylation by the MLL1 core complex, which is associated with a loss of the ability of MLL1 to interact with WRAD or with the RbBP5/Ash2L heterodimer.
Title: A non-active-site SET domain surface crucial for the interaction of MLL1 and the RbBP5/Ash2L heterodimer within MLL family core complexes.

Data indicate that MLL1 methylates Ash2L in the absence of histone H3, but only when assembled within a complex with WDR5 and RbBP5.
Title: Automethylation activities within the mixed lineage leukemia-1 (MLL1) core complex reveal evidence supporting a "two-active site" model for multiple histone H3 lysine 4 methylation.

The following RBBP5 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the RBBP5 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

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***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu15892	NM_001193272.2 Latest version!	Homo sapiens RB binding protein 5, histone lysine methyltransferase complex subunit (RBBP5), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$219.50-$307.30 $439.00
OHu15796	NM_001193273.2 Latest version!	Homo sapiens RB binding protein 5, histone lysine methyltransferase complex subunit (RBBP5), transcript variant 3, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$223.30 $319.00
OHu16030	NM_005057.4 Latest version!	Homo sapiens RB binding protein 5, histone lysine methyltransferase complex subunit (RBBP5), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$307.30 $439.00
OHu60214	XM_011509833.3 Latest version!	Homo sapiens RB binding protein 5, histone lysine methyltransferase complex subunit (RBBP5), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$307.30 $439.00
View Old Accession Versions >>
OHu15796	NM_001193273.1	Homo sapiens RB binding protein 5, histone lysine methyltransferase complex subunit (RBBP5), transcript variant 3, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$223.30 $319.00
OHu15892	NM_001193272.1	Homo sapiens RB binding protein 5, histone lysine methyltransferase complex subunit (RBBP5), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$219.50-$307.30 $439.00
OHu60214	XM_011509833.2	Homo sapiens retinoblastoma binding protein 5 (RBBP5), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$307.30 $439.00
OHu16030	NM_005057.3	Homo sapiens RB binding protein 5, histone lysine methyltransferase complex subunit (RBBP5), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$307.30 $439.00
Hide Old Accession Versions >>

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

RBBP5 ( NM_001193272.1 ) cDNA ORF clone, Homo sapiens(human) -> NP_001180201.1 Homo sapiens RB binding protein 5, histone lysine methyltransferase complex subunit (RBBP5), transcript variant 2, mRNA.

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CloneID	OHu15892
Clone ID Related Accession (Same CDS sequence)	NM_001193272.1 , NM_001193272.2
Accession Version	NM_001193272.1	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1503bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-02-22
Organism	Homo sapiens(human)
Product	retinoblastoma-binding protein 5 isoform 2
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from DA797022.1, AK290137.1, BC037284.2, AL583832.14 and BQ020418.1. Transcript Variant: This variant (2) uses a different splice site in the 3' coding region, compared to variant 1. The resulting protein (isoform 2) is shorter when it is compared to isoform 1. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC037284.2, SRR1660803.198082.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END##

ATGAACCTCG AGTTGCTGGA GTCCTTTGGG CAGAACTATC CAGAGGAAGC TGATGGAACT 
TTGGATTGTA TCAGCATGGC TTTGACTTGC ACCTTTAACA GGTGGGGCAC ACTGCTTGCA 
GTTGGCTGTA ATGATGGCCG AATTGTCATC TGGGATTTCT TGACAAGAGG CATTGCTAAA 
ATAATTAGTG CACACATCCA TCCAGTGTGT TCTTTATGCT GGAGCCGAGA TGGTCATAAA 
CTCGTGAGTG CTTCCACTGA TAACATAGTG TCACAGTGGG ATGTTCTTTC AGGCGACTGT 
GACCAGAGGT TTCGATTCCC TTCACCCATC TTAAAAGTCC AATATCATCC ACGAGATCAG 
AACAAGGTTC TCGTGTGTCC CATGAAATCT GCTCCTGTCA TGTTGACCCT TTCAGATTCC 
AAACATGTTG TTCTGCCGGT GGACGATGAC TCCGATTTGA ACGTTGTGGC ATCTTTTGAT 
AGGCGAGGGG AATATATTTA TACGGGAAAC GCAAAAGGCA AGATTTTGGT CCTAAAAACA 
GATTCTCAGG ATCTTGTTGC TTCCTTCAGA GTGACAACTG GAACAAGCAA TACCACAGCC 
ATTAAGTCAA TTGAGTTTGC CCGGAAGGGG AGTTGCTTTT TAATTAACAC GGCAGATCGA 
ATAATCAGAG TTTATGATGG CAGAGAAATC TTAACATGTG GAAGAGATGG AGAGCCTGAA 
CCTATGCAGA AATTGCAGGA TTTGGTGAAT AGGACCCCAT GGAAGAAATG TTGTTTCTCT 
GGGGATGGGG AATACATCGT GGCAGGTTCT GCCCGGCAGC ATGCCCTGTA CATCTGGGAG 
AAGAGCATTG GCAACCTGGT GAAGATTCTC CATGGGACGA GAGGAGAACT CCTCTTGGAT 
GTAGCTTGGC ATCCTGTTCG ACCCATCATA GCATCCATTT CCAGTGGAGT GGTATCTATC 
TGGGCACAGA ATCAAGTAGA AAACTGGAGT GCATTTGCAC CAGACTTCAA AGAATTGGAT 
GAAAATGTAG AATACGAAGA AAGGGAATCA GAGTTTGATA TTGAAGATGA AGATAAGAGT 
GAGCCTGAGC AGACAGGGGC TGATGCTGCA GAAGATGAGG AAGTGGATGT CACCAGCGTG 
GACCCTATTG CTGCCTTCTG TAGCAGTGAT GAAGAGCTGG AAGATTCAAA GGCTCTATTG 
TATTTACCCA TTGCCCCTGA GGTAGAAGAC CCAGAAGAAA ATCCTTACGG CCCCCCACCG 
GATGCAGTCC AAACCTCCTT GATGGATGAA GGGGCTAGTT CAGAGAAGAA GAGGCAGTCC 
TCAGCAGATG GGTCCCAGCC ACCTAAGAAG AAACCCAAAA CAACCAATAT AGAACTTCAA 
GGAGTACCAA ATGATGAAGT CCATCCACTA CTGGGTGTGA AGGGGGATGG CAAATCCAAG 
AAGAAGCAAG CAGGCCGGCC TAAAGGATCA AAAGCAGGAG GAGCAATCTC AGAACTGTTA 
TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001180201.1
CDS	150..1652
Translation	MNLELLESFGQNYPEEADGTLDCISMALTCTFNRWGTLLAVGCNDGRIVIWDFLTRGIAKIISAHIHPVCSLCWSRDGHKLVSASTDNIVSQWDVLSGDCDQRFRFPSPILKVQYHPRDQNKVLVCPMKSAPVMLTLSDSKHVVLPVDDDSDLNVVASFDRRGEYIYTGNAKGKILVLKTDSQDLVASFRVTTGTSNTTAIKSIEFARKGSCFLINTADRIIRVYDGREILTCGRDGEPEPMQKLQDLVNRTPWKKCCFSGDGEYIVAGSARQHALYIWEKSIGNLVKILHGTRGELLLDVAWHPVRPIIASISSGVVSIWAQNQVENWSAFAPDFKELDENVEYEERESEFDIEDEDKSEPEQTGADAAEDEEVDVTSVDPIAAFCSSDEELEDSKALLYLPIAPEVEDPEENPYGPPPDAVQTSLMDEGASSEKKRQSSADGSQPPKKKPKTTNIELQGVPNDEVHPLLGVKGDGKSKKKQAGRPKGSKAGGAISELL

Target ORF information:

RefSeq Version	NM_001193272.1
Organism	Homo sapiens(human)
Definition	Homo sapiens RB binding protein 5, histone lysine methyltransferase complex subunit (RBBP5), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001193272.1

ORF Insert Sequence:

ATGAACCTCG AGTTGCTGGA GTCCTTTGGG CAGAACTATC CAGAGGAAGC TGATGGAACT 
TTGGATTGTA TCAGCATGGC TTTGACTTGC ACCTTTAACA GGTGGGGCAC ACTGCTTGCA 
GTTGGCTGTA ATGATGGCCG AATTGTCATC TGGGATTTCT TGACAAGAGG CATTGCTAAA 
ATAATTAGTG CACACATCCA TCCAGTGTGT TCTTTATGCT GGAGCCGAGA TGGTCATAAA 
CTCGTGAGTG CTTCCACTGA TAACATAGTG TCACAGTGGG ATGTTCTTTC AGGCGACTGT 
GACCAGAGGT TTCGATTCCC TTCACCCATC TTAAAAGTCC AATATCATCC ACGAGATCAG 
AACAAGGTTC TCGTGTGTCC CATGAAATCT GCTCCTGTCA TGTTGACCCT TTCAGATTCC 
AAACATGTTG TTCTGCCGGT GGACGATGAC TCCGATTTGA ACGTTGTGGC ATCTTTTGAT 
AGGCGAGGGG AATATATTTA TACGGGAAAC GCAAAAGGCA AGATTTTGGT CCTAAAAACA 
GATTCTCAGG ATCTTGTTGC TTCCTTCAGA GTGACAACTG GAACAAGCAA TACCACAGCC 
ATTAAGTCAA TTGAGTTTGC CCGGAAGGGG AGTTGCTTTT TAATTAACAC GGCAGATCGA 
ATAATCAGAG TTTATGATGG CAGAGAAATC TTAACATGTG GAAGAGATGG AGAGCCTGAA 
CCTATGCAGA AATTGCAGGA TTTGGTGAAT AGGACCCCAT GGAAGAAATG TTGTTTCTCT 
GGGGATGGGG AATACATCGT GGCAGGTTCT GCCCGGCAGC ATGCCCTGTA CATCTGGGAG 
AAGAGCATTG GCAACCTGGT GAAGATTCTC CATGGGACGA GAGGAGAACT CCTCTTGGAT 
GTAGCTTGGC ATCCTGTTCG ACCCATCATA GCATCCATTT CCAGTGGAGT GGTATCTATC 
TGGGCACAGA ATCAAGTAGA AAACTGGAGT GCATTTGCAC CAGACTTCAA AGAATTGGAT 
GAAAATGTAG AATACGAAGA AAGGGAATCA GAGTTTGATA TTGAAGATGA AGATAAGAGT 
GAGCCTGAGC AGACAGGGGC TGATGCTGCA GAAGATGAGG AAGTGGATGT CACCAGCGTG 
GACCCTATTG CTGCCTTCTG TAGCAGTGAT GAAGAGCTGG AAGATTCAAA GGCTCTATTG 
TATTTACCCA TTGCCCCTGA GGTAGAAGAC CCAGAAGAAA ATCCTTACGG CCCCCCACCG 
GATGCAGTCC AAACCTCCTT GATGGATGAA GGGGCTAGTT CAGAGAAGAA GAGGCAGTCC 
TCAGCAGATG GGTCCCAGCC ACCTAAGAAG AAACCCAAAA CAACCAATAT AGAACTTCAA 
GGAGTACCAA ATGATGAAGT CCATCCACTA CTGGGTGTGA AGGGGGATGG CAAATCCAAG 
AAGAAGCAAG CAGGCCGGCC TAAAGGATCA AAAGCAGGAG GAGCAATCTC AGAACTGTTA 
TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RBBP5 ( NM_001193272.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_001180201.1 Homo sapiens RB binding protein 5, histone lysine methyltransferase complex subunit (RBBP5), transcript variant 2, mRNA.

Price & Availability↑

CloneID	OHu15892
Clone ID Related Accession (Same CDS sequence)	NM_001193272.1 , NM_001193272.2
Accession Version	NM_001193272.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1503bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2020-01-03
Organism	Homo sapiens(human)
Product	retinoblastoma-binding protein 5 isoform 2
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from DA797022.1, AK290137.1, BC037284.2, AL583832.14 and BQ020418.1. On May 31, 2019 this sequence version replaced NM_001193272.1. Transcript Variant: This variant (2) uses a different splice site in the 3' coding region, compared to variant 1. The resulting protein (isoform 2) is shorter when it is compared to isoform 1. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC037284.2, SRR1660803.198082.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END##

ATGAACCTCG AGTTGCTGGA GTCCTTTGGG CAGAACTATC CAGAGGAAGC TGATGGAACT 
TTGGATTGTA TCAGCATGGC TTTGACTTGC ACCTTTAACA GGTGGGGCAC ACTGCTTGCA 
GTTGGCTGTA ATGATGGCCG AATTGTCATC TGGGATTTCT TGACAAGAGG CATTGCTAAA 
ATAATTAGTG CACACATCCA TCCAGTGTGT TCTTTATGCT GGAGCCGAGA TGGTCATAAA 
CTCGTGAGTG CTTCCACTGA TAACATAGTG TCACAGTGGG ATGTTCTTTC AGGCGACTGT 
GACCAGAGGT TTCGATTCCC TTCACCCATC TTAAAAGTCC AATATCATCC ACGAGATCAG 
AACAAGGTTC TCGTGTGTCC CATGAAATCT GCTCCTGTCA TGTTGACCCT TTCAGATTCC 
AAACATGTTG TTCTGCCGGT GGACGATGAC TCCGATTTGA ACGTTGTGGC ATCTTTTGAT 
AGGCGAGGGG AATATATTTA TACGGGAAAC GCAAAAGGCA AGATTTTGGT CCTAAAAACA 
GATTCTCAGG ATCTTGTTGC TTCCTTCAGA GTGACAACTG GAACAAGCAA TACCACAGCC 
ATTAAGTCAA TTGAGTTTGC CCGGAAGGGG AGTTGCTTTT TAATTAACAC GGCAGATCGA 
ATAATCAGAG TTTATGATGG CAGAGAAATC TTAACATGTG GAAGAGATGG AGAGCCTGAA 
CCTATGCAGA AATTGCAGGA TTTGGTGAAT AGGACCCCAT GGAAGAAATG TTGTTTCTCT 
GGGGATGGGG AATACATCGT GGCAGGTTCT GCCCGGCAGC ATGCCCTGTA CATCTGGGAG 
AAGAGCATTG GCAACCTGGT GAAGATTCTC CATGGGACGA GAGGAGAACT CCTCTTGGAT 
GTAGCTTGGC ATCCTGTTCG ACCCATCATA GCATCCATTT CCAGTGGAGT GGTATCTATC 
TGGGCACAGA ATCAAGTAGA AAACTGGAGT GCATTTGCAC CAGACTTCAA AGAATTGGAT 
GAAAATGTAG AATACGAAGA AAGGGAATCA GAGTTTGATA TTGAAGATGA AGATAAGAGT 
GAGCCTGAGC AGACAGGGGC TGATGCTGCA GAAGATGAGG AAGTGGATGT CACCAGCGTG 
GACCCTATTG CTGCCTTCTG TAGCAGTGAT GAAGAGCTGG AAGATTCAAA GGCTCTATTG 
TATTTACCCA TTGCCCCTGA GGTAGAAGAC CCAGAAGAAA ATCCTTACGG CCCCCCACCG 
GATGCAGTCC AAACCTCCTT GATGGATGAA GGGGCTAGTT CAGAGAAGAA GAGGCAGTCC 
TCAGCAGATG GGTCCCAGCC ACCTAAGAAG AAACCCAAAA CAACCAATAT AGAACTTCAA 
GGAGTACCAA ATGATGAAGT CCATCCACTA CTGGGTGTGA AGGGGGATGG CAAATCCAAG 
AAGAAGCAAG CAGGCCGGCC TAAAGGATCA AAAGCAGGAG GAGCAATCTC AGAACTGTTA 
TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001180201.1
CDS	106..1608
Translation	MNLELLESFGQNYPEEADGTLDCISMALTCTFNRWGTLLAVGCNDGRIVIWDFLTRGIAKIISAHIHPVCSLCWSRDGHKLVSASTDNIVSQWDVLSGDCDQRFRFPSPILKVQYHPRDQNKVLVCPMKSAPVMLTLSDSKHVVLPVDDDSDLNVVASFDRRGEYIYTGNAKGKILVLKTDSQDLVASFRVTTGTSNTTAIKSIEFARKGSCFLINTADRIIRVYDGREILTCGRDGEPEPMQKLQDLVNRTPWKKCCFSGDGEYIVAGSARQHALYIWEKSIGNLVKILHGTRGELLLDVAWHPVRPIIASISSGVVSIWAQNQVENWSAFAPDFKELDENVEYEERESEFDIEDEDKSEPEQTGADAAEDEEVDVTSVDPIAAFCSSDEELEDSKALLYLPIAPEVEDPEENPYGPPPDAVQTSLMDEGASSEKKRQSSADGSQPPKKKPKTTNIELQGVPNDEVHPLLGVKGDGKSKKKQAGRPKGSKAGGAISELL

Target ORF information:

RefSeq Version	NM_001193272.2
Organism	Homo sapiens(human)
Definition	Homo sapiens RB binding protein 5, histone lysine methyltransferase complex subunit (RBBP5), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001193272.2

ORF Insert Sequence:

ATGAACCTCG AGTTGCTGGA GTCCTTTGGG CAGAACTATC CAGAGGAAGC TGATGGAACT 
TTGGATTGTA TCAGCATGGC TTTGACTTGC ACCTTTAACA GGTGGGGCAC ACTGCTTGCA 
GTTGGCTGTA ATGATGGCCG AATTGTCATC TGGGATTTCT TGACAAGAGG CATTGCTAAA 
ATAATTAGTG CACACATCCA TCCAGTGTGT TCTTTATGCT GGAGCCGAGA TGGTCATAAA 
CTCGTGAGTG CTTCCACTGA TAACATAGTG TCACAGTGGG ATGTTCTTTC AGGCGACTGT 
GACCAGAGGT TTCGATTCCC TTCACCCATC TTAAAAGTCC AATATCATCC ACGAGATCAG 
AACAAGGTTC TCGTGTGTCC CATGAAATCT GCTCCTGTCA TGTTGACCCT TTCAGATTCC 
AAACATGTTG TTCTGCCGGT GGACGATGAC TCCGATTTGA ACGTTGTGGC ATCTTTTGAT 
AGGCGAGGGG AATATATTTA TACGGGAAAC GCAAAAGGCA AGATTTTGGT CCTAAAAACA 
GATTCTCAGG ATCTTGTTGC TTCCTTCAGA GTGACAACTG GAACAAGCAA TACCACAGCC 
ATTAAGTCAA TTGAGTTTGC CCGGAAGGGG AGTTGCTTTT TAATTAACAC GGCAGATCGA 
ATAATCAGAG TTTATGATGG CAGAGAAATC TTAACATGTG GAAGAGATGG AGAGCCTGAA 
CCTATGCAGA AATTGCAGGA TTTGGTGAAT AGGACCCCAT GGAAGAAATG TTGTTTCTCT 
GGGGATGGGG AATACATCGT GGCAGGTTCT GCCCGGCAGC ATGCCCTGTA CATCTGGGAG 
AAGAGCATTG GCAACCTGGT GAAGATTCTC CATGGGACGA GAGGAGAACT CCTCTTGGAT 
GTAGCTTGGC ATCCTGTTCG ACCCATCATA GCATCCATTT CCAGTGGAGT GGTATCTATC 
TGGGCACAGA ATCAAGTAGA AAACTGGAGT GCATTTGCAC CAGACTTCAA AGAATTGGAT 
GAAAATGTAG AATACGAAGA AAGGGAATCA GAGTTTGATA TTGAAGATGA AGATAAGAGT 
GAGCCTGAGC AGACAGGGGC TGATGCTGCA GAAGATGAGG AAGTGGATGT CACCAGCGTG 
GACCCTATTG CTGCCTTCTG TAGCAGTGAT GAAGAGCTGG AAGATTCAAA GGCTCTATTG 
TATTTACCCA TTGCCCCTGA GGTAGAAGAC CCAGAAGAAA ATCCTTACGG CCCCCCACCG 
GATGCAGTCC AAACCTCCTT GATGGATGAA GGGGCTAGTT CAGAGAAGAA GAGGCAGTCC 
TCAGCAGATG GGTCCCAGCC ACCTAAGAAG AAACCCAAAA CAACCAATAT AGAACTTCAA 
GGAGTACCAA ATGATGAAGT CCATCCACTA CTGGGTGTGA AGGGGGATGG CAAATCCAAG 
AAGAAGCAAG CAGGCCGGCC TAAAGGATCA AAAGCAGGAG GAGCAATCTC AGAACTGTTA 
TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RBBP5 ( NM_001193273.1 ) cDNA ORF clone, Homo sapiens(human) -> NP_001180202.1 Homo sapiens RB binding protein 5, histone lysine methyltransferase complex subunit (RBBP5), transcript variant 3, mRNA.

Price & Availability↑

CloneID	OHu15796
Clone ID Related Accession (Same CDS sequence)	NM_001193273.1 , NM_001193273.2
Accession Version	NM_001193273.1	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1233bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2018-06-23
Organism	Homo sapiens(human)
Product	retinoblastoma-binding protein 5 isoform 3
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from DA797022.1, AK296978.1, BC075059.2, AL583832.14 and BQ020418.1. Transcript Variant: This variant (3) uses two different splice sites in the coding region which results in the use of a downstream start codon, compared to variant 1. The resulting protein (isoform 3) is shorter when it is compared to isoform 1. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AK296978.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END##

ATGAAATCTG CTCCTGTCAT GTTGACCCTT TCAGATTCCA AACATGTTGT TCTGCCGGTG 
GACGATGACT CCGATTTGAA CGTTGTGGCA TCTTTTGATA GGCGAGGGGA ATATATTTAT 
ACGGGAAACG CAAAAGGCAA GATTTTGGTC CTAAAAACAG ATTCTCAGGA TCTTGTTGCT 
TCCTTCAGAG TGACAACTGG AACAAGCAAT ACCACAGCCA TTAAGTCAAT TGAGTTTGCC 
CGGAAGGGGA GTTGCTTTTT AATTAACACG GCAGATCGAA TAATCAGAGT TTATGATGGC 
AGAGAAATCT TAACATGTGG AAGAGATGGA GAGCCTGAAC CTATGCAGAA ATTGCAGGAT 
TTGGTGAATA GGACCCCATG GAAGAAATGT TGTTTCTCTG GGGATGGGGA ATACATCGTG 
GCAGGTTCTG CCCGGCAGCA TGCCCTGTAC ATCTGGGAGA AGAGCATTGG CAACCTGGTG 
AAGATTCTCC ATGGGACGAG AGGAGAACTC CTCTTGGATG TAGCTTGGCA TCCTGTTCGA 
CCCATCATAG CATCCATTTC CAGTGGAGTG GTATCTATCT GGGCACAGAA TCAAGTAGAA 
AACTGGAGTG CATTTGCACC AGACTTCAAA GAATTGGATG AAAATGTAGA ATACGAAGAA 
AGGGAATCAG AGTTTGATAT TGAAGATGAA GATAAGAGTG AGCCTGAGCA GACAGGGGCT 
GATGCTGCAG AAGATGAGGA AGTGGATGTC ACCAGCGTGG ACCCTATTGC TGCCTTCTGT 
AGCAGTGATG AAGAGCTGGA AGATTCAAAG GCTCTATTGT ATTTACCCAT TGCCCCTGAG 
GTAGAAGACC CAGAAGAAAA TCCTTACGGC CCCCCACCGG ATGCAGTCCA AACCTCCTTG 
ATGGATGAAG GGGCTAGTTC AGAGAAGAAG AGGCAGTCCT CAGCAGATGG GTCCCAGCCA 
CCTAAGAAGA AACCCAAAAC AACCAATATA GAACTTCAAG GAGTACCAAA TGATGAAGTC 
CATCCACTAC TGGGTGTGAA GGGGGATGGC AAATCCAAGA AGAAGCAAGC AGGCCGGCCT 
AAAGGATCAA AAGGTAAAGA GAAAGATTCT CCATTTAAAC CGAAACTCTA CAAAGGGGAC 
AGAGGTTTAC CTCTGGAAGG ATCAGCGAAG GGTAAAGTGC AGGCGGAACT CAGCCAGCCC 
TTGACAGGAG GAGCAATCTC AGAACTGTTA TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001180202.1
CDS	475..1707
Translation	MKSAPVMLTLSDSKHVVLPVDDDSDLNVVASFDRRGEYIYTGNAKGKILVLKTDSQDLVASFRVTTGTSNTTAIKSIEFARKGSCFLINTADRIIRVYDGREILTCGRDGEPEPMQKLQDLVNRTPWKKCCFSGDGEYIVAGSARQHALYIWEKSIGNLVKILHGTRGELLLDVAWHPVRPIIASISSGVVSIWAQNQVENWSAFAPDFKELDENVEYEERESEFDIEDEDKSEPEQTGADAAEDEEVDVTSVDPIAAFCSSDEELEDSKALLYLPIAPEVEDPEENPYGPPPDAVQTSLMDEGASSEKKRQSSADGSQPPKKKPKTTNIELQGVPNDEVHPLLGVKGDGKSKKKQAGRPKGSKGKEKDSPFKPKLYKGDRGLPLEGSAKGKVQAELSQPLTGGAISELL

Target ORF information:

RefSeq Version	NM_001193273.1
Organism	Homo sapiens(human)
Definition	Homo sapiens RB binding protein 5, histone lysine methyltransferase complex subunit (RBBP5), transcript variant 3, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001193273.1

ORF Insert Sequence:

ATGAAATCTG CTCCTGTCAT GTTGACCCTT TCAGATTCCA AACATGTTGT TCTGCCGGTG 
GACGATGACT CCGATTTGAA CGTTGTGGCA TCTTTTGATA GGCGAGGGGA ATATATTTAT 
ACGGGAAACG CAAAAGGCAA GATTTTGGTC CTAAAAACAG ATTCTCAGGA TCTTGTTGCT 
TCCTTCAGAG TGACAACTGG AACAAGCAAT ACCACAGCCA TTAAGTCAAT TGAGTTTGCC 
CGGAAGGGGA GTTGCTTTTT AATTAACACG GCAGATCGAA TAATCAGAGT TTATGATGGC 
AGAGAAATCT TAACATGTGG AAGAGATGGA GAGCCTGAAC CTATGCAGAA ATTGCAGGAT 
TTGGTGAATA GGACCCCATG GAAGAAATGT TGTTTCTCTG GGGATGGGGA ATACATCGTG 
GCAGGTTCTG CCCGGCAGCA TGCCCTGTAC ATCTGGGAGA AGAGCATTGG CAACCTGGTG 
AAGATTCTCC ATGGGACGAG AGGAGAACTC CTCTTGGATG TAGCTTGGCA TCCTGTTCGA 
CCCATCATAG CATCCATTTC CAGTGGAGTG GTATCTATCT GGGCACAGAA TCAAGTAGAA 
AACTGGAGTG CATTTGCACC AGACTTCAAA GAATTGGATG AAAATGTAGA ATACGAAGAA 
AGGGAATCAG AGTTTGATAT TGAAGATGAA GATAAGAGTG AGCCTGAGCA GACAGGGGCT 
GATGCTGCAG AAGATGAGGA AGTGGATGTC ACCAGCGTGG ACCCTATTGC TGCCTTCTGT 
AGCAGTGATG AAGAGCTGGA AGATTCAAAG GCTCTATTGT ATTTACCCAT TGCCCCTGAG 
GTAGAAGACC CAGAAGAAAA TCCTTACGGC CCCCCACCGG ATGCAGTCCA AACCTCCTTG 
ATGGATGAAG GGGCTAGTTC AGAGAAGAAG AGGCAGTCCT CAGCAGATGG GTCCCAGCCA 
CCTAAGAAGA AACCCAAAAC AACCAATATA GAACTTCAAG GAGTACCAAA TGATGAAGTC 
CATCCACTAC TGGGTGTGAA GGGGGATGGC AAATCCAAGA AGAAGCAAGC AGGCCGGCCT 
AAAGGATCAA AAGGTAAAGA GAAAGATTCT CCATTTAAAC CGAAACTCTA CAAAGGGGAC 
AGAGGTTTAC CTCTGGAAGG ATCAGCGAAG GGTAAAGTGC AGGCGGAACT CAGCCAGCCC 
TTGACAGGAG GAGCAATCTC AGAACTGTTA TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RBBP5 ( NM_001193273.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_001180202.1 Homo sapiens RB binding protein 5, histone lysine methyltransferase complex subunit (RBBP5), transcript variant 3, mRNA.

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CloneID	OHu15796
Clone ID Related Accession (Same CDS sequence)	NM_001193273.1 , NM_001193273.2
Accession Version	NM_001193273.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1233bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2020-01-03
Organism	Homo sapiens(human)
Product	retinoblastoma-binding protein 5 isoform 3
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from DA797022.1, AK296978.1, BC075059.2, AL583832.14 and BQ020418.1. On May 31, 2019 this sequence version replaced NM_001193273.1. Transcript Variant: This variant (3) uses two different splice sites in the coding region which results in the use of a downstream start codon, compared to variant 1. The resulting protein (isoform 3) is shorter when it is compared to isoform 1. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AK296978.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END##

ATGAAATCTG CTCCTGTCAT GTTGACCCTT TCAGATTCCA AACATGTTGT TCTGCCGGTG 
GACGATGACT CCGATTTGAA CGTTGTGGCA TCTTTTGATA GGCGAGGGGA ATATATTTAT 
ACGGGAAACG CAAAAGGCAA GATTTTGGTC CTAAAAACAG ATTCTCAGGA TCTTGTTGCT 
TCCTTCAGAG TGACAACTGG AACAAGCAAT ACCACAGCCA TTAAGTCAAT TGAGTTTGCC 
CGGAAGGGGA GTTGCTTTTT AATTAACACG GCAGATCGAA TAATCAGAGT TTATGATGGC 
AGAGAAATCT TAACATGTGG AAGAGATGGA GAGCCTGAAC CTATGCAGAA ATTGCAGGAT 
TTGGTGAATA GGACCCCATG GAAGAAATGT TGTTTCTCTG GGGATGGGGA ATACATCGTG 
GCAGGTTCTG CCCGGCAGCA TGCCCTGTAC ATCTGGGAGA AGAGCATTGG CAACCTGGTG 
AAGATTCTCC ATGGGACGAG AGGAGAACTC CTCTTGGATG TAGCTTGGCA TCCTGTTCGA 
CCCATCATAG CATCCATTTC CAGTGGAGTG GTATCTATCT GGGCACAGAA TCAAGTAGAA 
AACTGGAGTG CATTTGCACC AGACTTCAAA GAATTGGATG AAAATGTAGA ATACGAAGAA 
AGGGAATCAG AGTTTGATAT TGAAGATGAA GATAAGAGTG AGCCTGAGCA GACAGGGGCT 
GATGCTGCAG AAGATGAGGA AGTGGATGTC ACCAGCGTGG ACCCTATTGC TGCCTTCTGT 
AGCAGTGATG AAGAGCTGGA AGATTCAAAG GCTCTATTGT ATTTACCCAT TGCCCCTGAG 
GTAGAAGACC CAGAAGAAAA TCCTTACGGC CCCCCACCGG ATGCAGTCCA AACCTCCTTG 
ATGGATGAAG GGGCTAGTTC AGAGAAGAAG AGGCAGTCCT CAGCAGATGG GTCCCAGCCA 
CCTAAGAAGA AACCCAAAAC AACCAATATA GAACTTCAAG GAGTACCAAA TGATGAAGTC 
CATCCACTAC TGGGTGTGAA GGGGGATGGC AAATCCAAGA AGAAGCAAGC AGGCCGGCCT 
AAAGGATCAA AAGGTAAAGA GAAAGATTCT CCATTTAAAC CGAAACTCTA CAAAGGGGAC 
AGAGGTTTAC CTCTGGAAGG ATCAGCGAAG GGTAAAGTGC AGGCGGAACT CAGCCAGCCC 
TTGACAGGAG GAGCAATCTC AGAACTGTTA TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001180202.1
CDS	431..1663
Translation	MKSAPVMLTLSDSKHVVLPVDDDSDLNVVASFDRRGEYIYTGNAKGKILVLKTDSQDLVASFRVTTGTSNTTAIKSIEFARKGSCFLINTADRIIRVYDGREILTCGRDGEPEPMQKLQDLVNRTPWKKCCFSGDGEYIVAGSARQHALYIWEKSIGNLVKILHGTRGELLLDVAWHPVRPIIASISSGVVSIWAQNQVENWSAFAPDFKELDENVEYEERESEFDIEDEDKSEPEQTGADAAEDEEVDVTSVDPIAAFCSSDEELEDSKALLYLPIAPEVEDPEENPYGPPPDAVQTSLMDEGASSEKKRQSSADGSQPPKKKPKTTNIELQGVPNDEVHPLLGVKGDGKSKKKQAGRPKGSKGKEKDSPFKPKLYKGDRGLPLEGSAKGKVQAELSQPLTGGAISELL

Target ORF information:

RefSeq Version	NM_001193273.2
Organism	Homo sapiens(human)
Definition	Homo sapiens RB binding protein 5, histone lysine methyltransferase complex subunit (RBBP5), transcript variant 3, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001193273.2

ORF Insert Sequence:

ATGAAATCTG CTCCTGTCAT GTTGACCCTT TCAGATTCCA AACATGTTGT TCTGCCGGTG 
GACGATGACT CCGATTTGAA CGTTGTGGCA TCTTTTGATA GGCGAGGGGA ATATATTTAT 
ACGGGAAACG CAAAAGGCAA GATTTTGGTC CTAAAAACAG ATTCTCAGGA TCTTGTTGCT 
TCCTTCAGAG TGACAACTGG AACAAGCAAT ACCACAGCCA TTAAGTCAAT TGAGTTTGCC 
CGGAAGGGGA GTTGCTTTTT AATTAACACG GCAGATCGAA TAATCAGAGT TTATGATGGC 
AGAGAAATCT TAACATGTGG AAGAGATGGA GAGCCTGAAC CTATGCAGAA ATTGCAGGAT 
TTGGTGAATA GGACCCCATG GAAGAAATGT TGTTTCTCTG GGGATGGGGA ATACATCGTG 
GCAGGTTCTG CCCGGCAGCA TGCCCTGTAC ATCTGGGAGA AGAGCATTGG CAACCTGGTG 
AAGATTCTCC ATGGGACGAG AGGAGAACTC CTCTTGGATG TAGCTTGGCA TCCTGTTCGA 
CCCATCATAG CATCCATTTC CAGTGGAGTG GTATCTATCT GGGCACAGAA TCAAGTAGAA 
AACTGGAGTG CATTTGCACC AGACTTCAAA GAATTGGATG AAAATGTAGA ATACGAAGAA 
AGGGAATCAG AGTTTGATAT TGAAGATGAA GATAAGAGTG AGCCTGAGCA GACAGGGGCT 
GATGCTGCAG AAGATGAGGA AGTGGATGTC ACCAGCGTGG ACCCTATTGC TGCCTTCTGT 
AGCAGTGATG AAGAGCTGGA AGATTCAAAG GCTCTATTGT ATTTACCCAT TGCCCCTGAG 
GTAGAAGACC CAGAAGAAAA TCCTTACGGC CCCCCACCGG ATGCAGTCCA AACCTCCTTG 
ATGGATGAAG GGGCTAGTTC AGAGAAGAAG AGGCAGTCCT CAGCAGATGG GTCCCAGCCA 
CCTAAGAAGA AACCCAAAAC AACCAATATA GAACTTCAAG GAGTACCAAA TGATGAAGTC 
CATCCACTAC TGGGTGTGAA GGGGGATGGC AAATCCAAGA AGAAGCAAGC AGGCCGGCCT 
AAAGGATCAA AAGGTAAAGA GAAAGATTCT CCATTTAAAC CGAAACTCTA CAAAGGGGAC 
AGAGGTTTAC CTCTGGAAGG ATCAGCGAAG GGTAAAGTGC AGGCGGAACT CAGCCAGCCC 
TTGACAGGAG GAGCAATCTC AGAACTGTTA TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RBBP5 ( NM_005057.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_005048.2 Homo sapiens RB binding protein 5, histone lysine methyltransferase complex subunit (RBBP5), transcript variant 1, mRNA.

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CloneID	OHu16030
Clone ID Related Accession (Same CDS sequence)	NM_005057.3 , NM_005057.4
Accession Version	NM_005057.3	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1617bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2017-11-11
Organism	Homo sapiens(human)
Product	retinoblastoma-binding protein 5 isoform 1
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from DA797022.1, BC075059.2, AL583832.14 and BQ020418.1. On Jul 17, 2010 this sequence version replaced NM_005057.2. Transcript Variant: This variant (1) represents the longest transcript and encodes the longest protein (isoform 1). Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1803615.96823.1, SRR1660803.201502.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END##

ATGAACCTCG AGTTGCTGGA GTCCTTTGGG CAGAACTATC CAGAGGAAGC TGATGGAACT 
TTGGATTGTA TCAGCATGGC TTTGACTTGC ACCTTTAACA GGTGGGGCAC ACTGCTTGCA 
GTTGGCTGTA ATGATGGCCG AATTGTCATC TGGGATTTCT TGACAAGAGG CATTGCTAAA 
ATAATTAGTG CACACATCCA TCCAGTGTGT TCTTTATGCT GGAGCCGAGA TGGTCATAAA 
CTCGTGAGTG CTTCCACTGA TAACATAGTG TCACAGTGGG ATGTTCTTTC AGGCGACTGT 
GACCAGAGGT TTCGATTCCC TTCACCCATC TTAAAAGTCC AATATCATCC ACGAGATCAG 
AACAAGGTTC TCGTGTGTCC CATGAAATCT GCTCCTGTCA TGTTGACCCT TTCAGATTCC 
AAACATGTTG TTCTGCCGGT GGACGATGAC TCCGATTTGA ACGTTGTGGC ATCTTTTGAT 
AGGCGAGGGG AATATATTTA TACGGGAAAC GCAAAAGGCA AGATTTTGGT CCTAAAAACA 
GATTCTCAGG ATCTTGTTGC TTCCTTCAGA GTGACAACTG GAACAAGCAA TACCACAGCC 
ATTAAGTCAA TTGAGTTTGC CCGGAAGGGG AGTTGCTTTT TAATTAACAC GGCAGATCGA 
ATAATCAGAG TTTATGATGG CAGAGAAATC TTAACATGTG GAAGAGATGG AGAGCCTGAA 
CCTATGCAGA AATTGCAGGA TTTGGTGAAT AGGACCCCAT GGAAGAAATG TTGTTTCTCT 
GGGGATGGGG AATACATCGT GGCAGGTTCT GCCCGGCAGC ATGCCCTGTA CATCTGGGAG 
AAGAGCATTG GCAACCTGGT GAAGATTCTC CATGGGACGA GAGGAGAACT CCTCTTGGAT 
GTAGCTTGGC ATCCTGTTCG ACCCATCATA GCATCCATTT CCAGTGGAGT GGTATCTATC 
TGGGCACAGA ATCAAGTAGA AAACTGGAGT GCATTTGCAC CAGACTTCAA AGAATTGGAT 
GAAAATGTAG AATACGAAGA AAGGGAATCA GAGTTTGATA TTGAAGATGA AGATAAGAGT 
GAGCCTGAGC AGACAGGGGC TGATGCTGCA GAAGATGAGG AAGTGGATGT CACCAGCGTG 
GACCCTATTG CTGCCTTCTG TAGCAGTGAT GAAGAGCTGG AAGATTCAAA GGCTCTATTG 
TATTTACCCA TTGCCCCTGA GGTAGAAGAC CCAGAAGAAA ATCCTTACGG CCCCCCACCG 
GATGCAGTCC AAACCTCCTT GATGGATGAA GGGGCTAGTT CAGAGAAGAA GAGGCAGTCC 
TCAGCAGATG GGTCCCAGCC ACCTAAGAAG AAACCCAAAA CAACCAATAT AGAACTTCAA 
GGAGTACCAA ATGATGAAGT CCATCCACTA CTGGGTGTGA AGGGGGATGG CAAATCCAAG 
AAGAAGCAAG CAGGCCGGCC TAAAGGATCA AAAGGTAAAG AGAAAGATTC TCCATTTAAA 
CCGAAACTCT ACAAAGGGGA CAGAGGTTTA CCTCTGGAAG GATCAGCGAA GGGTAAAGTG 
CAGGCGGAAC TCAGCCAGCC CTTGACAGCA GGAGGAGCAA TCTCAGAACT GTTATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_005048.2
CDS	150..1766
Translation	MNLELLESFGQNYPEEADGTLDCISMALTCTFNRWGTLLAVGCNDGRIVIWDFLTRGIAKIISAHIHPVCSLCWSRDGHKLVSASTDNIVSQWDVLSGDCDQRFRFPSPILKVQYHPRDQNKVLVCPMKSAPVMLTLSDSKHVVLPVDDDSDLNVVASFDRRGEYIYTGNAKGKILVLKTDSQDLVASFRVTTGTSNTTAIKSIEFARKGSCFLINTADRIIRVYDGREILTCGRDGEPEPMQKLQDLVNRTPWKKCCFSGDGEYIVAGSARQHALYIWEKSIGNLVKILHGTRGELLLDVAWHPVRPIIASISSGVVSIWAQNQVENWSAFAPDFKELDENVEYEERESEFDIEDEDKSEPEQTGADAAEDEEVDVTSVDPIAAFCSSDEELEDSKALLYLPIAPEVEDPEENPYGPPPDAVQTSLMDEGASSEKKRQSSADGSQPPKKKPKTTNIELQGVPNDEVHPLLGVKGDGKSKKKQAGRPKGSKGKEKDSPFKPKLYKGDRGLPLEGSAKGKVQAELSQPLTAGGAISELL

Target ORF information:

RefSeq Version	NM_005057.3
Organism	Homo sapiens(human)
Definition	Homo sapiens RB binding protein 5, histone lysine methyltransferase complex subunit (RBBP5), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_005057.3

ORF Insert Sequence:

ATGAACCTCG AGTTGCTGGA GTCCTTTGGG CAGAACTATC CAGAGGAAGC TGATGGAACT 
TTGGATTGTA TCAGCATGGC TTTGACTTGC ACCTTTAACA GGTGGGGCAC ACTGCTTGCA 
GTTGGCTGTA ATGATGGCCG AATTGTCATC TGGGATTTCT TGACAAGAGG CATTGCTAAA 
ATAATTAGTG CACACATCCA TCCAGTGTGT TCTTTATGCT GGAGCCGAGA TGGTCATAAA 
CTCGTGAGTG CTTCCACTGA TAACATAGTG TCACAGTGGG ATGTTCTTTC AGGCGACTGT 
GACCAGAGGT TTCGATTCCC TTCACCCATC TTAAAAGTCC AATATCATCC ACGAGATCAG 
AACAAGGTTC TCGTGTGTCC CATGAAATCT GCTCCTGTCA TGTTGACCCT TTCAGATTCC 
AAACATGTTG TTCTGCCGGT GGACGATGAC TCCGATTTGA ACGTTGTGGC ATCTTTTGAT 
AGGCGAGGGG AATATATTTA TACGGGAAAC GCAAAAGGCA AGATTTTGGT CCTAAAAACA 
GATTCTCAGG ATCTTGTTGC TTCCTTCAGA GTGACAACTG GAACAAGCAA TACCACAGCC 
ATTAAGTCAA TTGAGTTTGC CCGGAAGGGG AGTTGCTTTT TAATTAACAC GGCAGATCGA 
ATAATCAGAG TTTATGATGG CAGAGAAATC TTAACATGTG GAAGAGATGG AGAGCCTGAA 
CCTATGCAGA AATTGCAGGA TTTGGTGAAT AGGACCCCAT GGAAGAAATG TTGTTTCTCT 
GGGGATGGGG AATACATCGT GGCAGGTTCT GCCCGGCAGC ATGCCCTGTA CATCTGGGAG 
AAGAGCATTG GCAACCTGGT GAAGATTCTC CATGGGACGA GAGGAGAACT CCTCTTGGAT 
GTAGCTTGGC ATCCTGTTCG ACCCATCATA GCATCCATTT CCAGTGGAGT GGTATCTATC 
TGGGCACAGA ATCAAGTAGA AAACTGGAGT GCATTTGCAC CAGACTTCAA AGAATTGGAT 
GAAAATGTAG AATACGAAGA AAGGGAATCA GAGTTTGATA TTGAAGATGA AGATAAGAGT 
GAGCCTGAGC AGACAGGGGC TGATGCTGCA GAAGATGAGG AAGTGGATGT CACCAGCGTG 
GACCCTATTG CTGCCTTCTG TAGCAGTGAT GAAGAGCTGG AAGATTCAAA GGCTCTATTG 
TATTTACCCA TTGCCCCTGA GGTAGAAGAC CCAGAAGAAA ATCCTTACGG CCCCCCACCG 
GATGCAGTCC AAACCTCCTT GATGGATGAA GGGGCTAGTT CAGAGAAGAA GAGGCAGTCC 
TCAGCAGATG GGTCCCAGCC ACCTAAGAAG AAACCCAAAA CAACCAATAT AGAACTTCAA 
GGAGTACCAA ATGATGAAGT CCATCCACTA CTGGGTGTGA AGGGGGATGG CAAATCCAAG 
AAGAAGCAAG CAGGCCGGCC TAAAGGATCA AAAGGTAAAG AGAAAGATTC TCCATTTAAA 
CCGAAACTCT ACAAAGGGGA CAGAGGTTTA CCTCTGGAAG GATCAGCGAA GGGTAAAGTG 
CAGGCGGAAC TCAGCCAGCC CTTGACAGCA GGAGGAGCAA TCTCAGAACT GTTATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RBBP5 ( NM_005057.4 ) cDNA ORF clone, Homo sapiens(human) -> NP_005048.2 Homo sapiens RB binding protein 5, histone lysine methyltransferase complex subunit (RBBP5), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OHu16030
Clone ID Related Accession (Same CDS sequence)	NM_005057.3 , NM_005057.4
Accession Version	NM_005057.4 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1617bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-30
Organism	Homo sapiens(human)
Product	retinoblastoma-binding protein 5 isoform 1
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from DA797022.1, BC075059.2, AL583832.14 and BQ020418.1. On Nov 22, 2018 this sequence version replaced NM_005057.3. Transcript Variant: This variant (1) represents the longest transcript and encodes the longest protein (isoform 1). Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1803615.96823.1, SRR1660803.201502.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000264515.11/ ENSP00000264515.6 RefSeq Select criteria :: based on conservation, expression, longest protein ##RefSeq-Attributes-END## COMPLETENESS: full length.

ATGAACCTCG AGTTGCTGGA GTCCTTTGGG CAGAACTATC CAGAGGAAGC TGATGGAACT 
TTGGATTGTA TCAGCATGGC TTTGACTTGC ACCTTTAACA GGTGGGGCAC ACTGCTTGCA 
GTTGGCTGTA ATGATGGCCG AATTGTCATC TGGGATTTCT TGACAAGAGG CATTGCTAAA 
ATAATTAGTG CACACATCCA TCCAGTGTGT TCTTTATGCT GGAGCCGAGA TGGTCATAAA 
CTCGTGAGTG CTTCCACTGA TAACATAGTG TCACAGTGGG ATGTTCTTTC AGGCGACTGT 
GACCAGAGGT TTCGATTCCC TTCACCCATC TTAAAAGTCC AATATCATCC ACGAGATCAG 
AACAAGGTTC TCGTGTGTCC CATGAAATCT GCTCCTGTCA TGTTGACCCT TTCAGATTCC 
AAACATGTTG TTCTGCCGGT GGACGATGAC TCCGATTTGA ACGTTGTGGC ATCTTTTGAT 
AGGCGAGGGG AATATATTTA TACGGGAAAC GCAAAAGGCA AGATTTTGGT CCTAAAAACA 
GATTCTCAGG ATCTTGTTGC TTCCTTCAGA GTGACAACTG GAACAAGCAA TACCACAGCC 
ATTAAGTCAA TTGAGTTTGC CCGGAAGGGG AGTTGCTTTT TAATTAACAC GGCAGATCGA 
ATAATCAGAG TTTATGATGG CAGAGAAATC TTAACATGTG GAAGAGATGG AGAGCCTGAA 
CCTATGCAGA AATTGCAGGA TTTGGTGAAT AGGACCCCAT GGAAGAAATG TTGTTTCTCT 
GGGGATGGGG AATACATCGT GGCAGGTTCT GCCCGGCAGC ATGCCCTGTA CATCTGGGAG 
AAGAGCATTG GCAACCTGGT GAAGATTCTC CATGGGACGA GAGGAGAACT CCTCTTGGAT 
GTAGCTTGGC ATCCTGTTCG ACCCATCATA GCATCCATTT CCAGTGGAGT GGTATCTATC 
TGGGCACAGA ATCAAGTAGA AAACTGGAGT GCATTTGCAC CAGACTTCAA AGAATTGGAT 
GAAAATGTAG AATACGAAGA AAGGGAATCA GAGTTTGATA TTGAAGATGA AGATAAGAGT 
GAGCCTGAGC AGACAGGGGC TGATGCTGCA GAAGATGAGG AAGTGGATGT CACCAGCGTG 
GACCCTATTG CTGCCTTCTG TAGCAGTGAT GAAGAGCTGG AAGATTCAAA GGCTCTATTG 
TATTTACCCA TTGCCCCTGA GGTAGAAGAC CCAGAAGAAA ATCCTTACGG CCCCCCACCG 
GATGCAGTCC AAACCTCCTT GATGGATGAA GGGGCTAGTT CAGAGAAGAA GAGGCAGTCC 
TCAGCAGATG GGTCCCAGCC ACCTAAGAAG AAACCCAAAA CAACCAATAT AGAACTTCAA 
GGAGTACCAA ATGATGAAGT CCATCCACTA CTGGGTGTGA AGGGGGATGG CAAATCCAAG 
AAGAAGCAAG CAGGCCGGCC TAAAGGATCA AAAGGTAAAG AGAAAGATTC TCCATTTAAA 
CCGAAACTCT ACAAAGGGGA CAGAGGTTTA CCTCTGGAAG GATCAGCGAA GGGTAAAGTG 
CAGGCGGAAC TCAGCCAGCC CTTGACAGCA GGAGGAGCAA TCTCAGAACT GTTATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_005048.2
CDS	106..1722
Translation	MNLELLESFGQNYPEEADGTLDCISMALTCTFNRWGTLLAVGCNDGRIVIWDFLTRGIAKIISAHIHPVCSLCWSRDGHKLVSASTDNIVSQWDVLSGDCDQRFRFPSPILKVQYHPRDQNKVLVCPMKSAPVMLTLSDSKHVVLPVDDDSDLNVVASFDRRGEYIYTGNAKGKILVLKTDSQDLVASFRVTTGTSNTTAIKSIEFARKGSCFLINTADRIIRVYDGREILTCGRDGEPEPMQKLQDLVNRTPWKKCCFSGDGEYIVAGSARQHALYIWEKSIGNLVKILHGTRGELLLDVAWHPVRPIIASISSGVVSIWAQNQVENWSAFAPDFKELDENVEYEERESEFDIEDEDKSEPEQTGADAAEDEEVDVTSVDPIAAFCSSDEELEDSKALLYLPIAPEVEDPEENPYGPPPDAVQTSLMDEGASSEKKRQSSADGSQPPKKKPKTTNIELQGVPNDEVHPLLGVKGDGKSKKKQAGRPKGSKGKEKDSPFKPKLYKGDRGLPLEGSAKGKVQAELSQPLTAGGAISELL

Target ORF information:

RefSeq Version	NM_005057.4
Organism	Homo sapiens(human)
Definition	Homo sapiens RB binding protein 5, histone lysine methyltransferase complex subunit (RBBP5), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_005057.4

ORF Insert Sequence:

ATGAACCTCG AGTTGCTGGA GTCCTTTGGG CAGAACTATC CAGAGGAAGC TGATGGAACT 
TTGGATTGTA TCAGCATGGC TTTGACTTGC ACCTTTAACA GGTGGGGCAC ACTGCTTGCA 
GTTGGCTGTA ATGATGGCCG AATTGTCATC TGGGATTTCT TGACAAGAGG CATTGCTAAA 
ATAATTAGTG CACACATCCA TCCAGTGTGT TCTTTATGCT GGAGCCGAGA TGGTCATAAA 
CTCGTGAGTG CTTCCACTGA TAACATAGTG TCACAGTGGG ATGTTCTTTC AGGCGACTGT 
GACCAGAGGT TTCGATTCCC TTCACCCATC TTAAAAGTCC AATATCATCC ACGAGATCAG 
AACAAGGTTC TCGTGTGTCC CATGAAATCT GCTCCTGTCA TGTTGACCCT TTCAGATTCC 
AAACATGTTG TTCTGCCGGT GGACGATGAC TCCGATTTGA ACGTTGTGGC ATCTTTTGAT 
AGGCGAGGGG AATATATTTA TACGGGAAAC GCAAAAGGCA AGATTTTGGT CCTAAAAACA 
GATTCTCAGG ATCTTGTTGC TTCCTTCAGA GTGACAACTG GAACAAGCAA TACCACAGCC 
ATTAAGTCAA TTGAGTTTGC CCGGAAGGGG AGTTGCTTTT TAATTAACAC GGCAGATCGA 
ATAATCAGAG TTTATGATGG CAGAGAAATC TTAACATGTG GAAGAGATGG AGAGCCTGAA 
CCTATGCAGA AATTGCAGGA TTTGGTGAAT AGGACCCCAT GGAAGAAATG TTGTTTCTCT 
GGGGATGGGG AATACATCGT GGCAGGTTCT GCCCGGCAGC ATGCCCTGTA CATCTGGGAG 
AAGAGCATTG GCAACCTGGT GAAGATTCTC CATGGGACGA GAGGAGAACT CCTCTTGGAT 
GTAGCTTGGC ATCCTGTTCG ACCCATCATA GCATCCATTT CCAGTGGAGT GGTATCTATC 
TGGGCACAGA ATCAAGTAGA AAACTGGAGT GCATTTGCAC CAGACTTCAA AGAATTGGAT 
GAAAATGTAG AATACGAAGA AAGGGAATCA GAGTTTGATA TTGAAGATGA AGATAAGAGT 
GAGCCTGAGC AGACAGGGGC TGATGCTGCA GAAGATGAGG AAGTGGATGT CACCAGCGTG 
GACCCTATTG CTGCCTTCTG TAGCAGTGAT GAAGAGCTGG AAGATTCAAA GGCTCTATTG 
TATTTACCCA TTGCCCCTGA GGTAGAAGAC CCAGAAGAAA ATCCTTACGG CCCCCCACCG 
GATGCAGTCC AAACCTCCTT GATGGATGAA GGGGCTAGTT CAGAGAAGAA GAGGCAGTCC 
TCAGCAGATG GGTCCCAGCC ACCTAAGAAG AAACCCAAAA CAACCAATAT AGAACTTCAA 
GGAGTACCAA ATGATGAAGT CCATCCACTA CTGGGTGTGA AGGGGGATGG CAAATCCAAG 
AAGAAGCAAG CAGGCCGGCC TAAAGGATCA AAAGGTAAAG AGAAAGATTC TCCATTTAAA 
CCGAAACTCT ACAAAGGGGA CAGAGGTTTA CCTCTGGAAG GATCAGCGAA GGGTAAAGTG 
CAGGCGGAAC TCAGCCAGCC CTTGACAGCA GGAGGAGCAA TCTCAGAACT GTTATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RBBP5 ( XM_011509833.3 ) cDNA ORF clone, Homo sapiens(human) -> XP_011508135.1 Homo sapiens RB binding protein 5, histone lysine methyltransferase complex subunit (RBBP5), transcript variant X1, mRNA.

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CloneID	OHu60214
Clone ID Related Accession (Same CDS sequence)	XM_011509833.3 , XM_011509833.2
Accession Version	XM_011509833.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1614bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-05
Organism	Homo sapiens(human)
Product	retinoblastoma-binding protein 5 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000001.11) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Mar 26, 2018 this sequence version replaced XM_011509833.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGAACCTCG AGTTGCTGGA GTCCTTTGGG CAGAACTATC CAGAGGAAGC TGATGGAACT 
TTGGATTGTA TCAGCATGGC TTTGACTTGC ACCTTTAACA GGTGGGGCAC ACTGCTTGCA 
GTTGGCTGTA ATGATGGCCG AATTGTCATC TGGGATTTCT TGACAAGAGG CATTGCTAAA 
ATAATTAGTG CACACATCCA TCCAGTGTGT TCTTTATGCT GGAGCCGAGA TGGTCATAAA 
CTCGTGAGTG CTTCCACTGA TAACATAGTG TCACAGTGGG ATGTTCTTTC AGGCGACTGT 
GACCAGAGGT TTCGATTCCC TTCACCCATC TTAAAAGTCC AATATCATCC ACGAGATCAG 
AACAAGGTTC TCGTGTGTCC CATGAAATCT GCTCCTGTCA TGTTGACCCT TTCAGATTCC 
AAACATGTTG TTCTGCCGGT GGACGATGAC TCCGATTTGA ACGTTGTGGC ATCTTTTGAT 
AGGCGAGGGG AATATATTTA TACGGGAAAC GCAAAAGGCA AGATTTTGGT CCTAAAAACA 
GATTCTCAGG ATCTTGTTGC TTCCTTCAGA GTGACAACTG GAACAAGCAA TACCACAGCC 
ATTAAGTCAA TTGAGTTTGC CCGGAAGGGG AGTTGCTTTT TAATTAACAC GGCAGATCGA 
ATAATCAGAG TTTATGATGG CAGAGAAATC TTAACATGTG GAAGAGATGG AGAGCCTGAA 
CCTATGCAGA AATTGCAGGA TTTGGTGAAT AGGACCCCAT GGAAGAAATG TTGTTTCTCT 
GGGGATGGGG AATACATCGT GGCAGGTTCT GCCCGGCAGC ATGCCCTGTA CATCTGGGAG 
AAGAGCATTG GCAACCTGGT GAAGATTCTC CATGGGACGA GAGGAGAACT CCTCTTGGAT 
GTAGCTTGGC ATCCTGTTCG ACCCATCATA GCATCCATTT CCAGTGGAGT GGTATCTATC 
TGGGCACAGA ATCAAGTAGA AAACTGGAGT GCATTTGCAC CAGACTTCAA AGAATTGGAT 
GAAAATGTAG AATACGAAGA AAGGGAATCA GAGTTTGATA TTGAAGATGA AGATAAGAGT 
GAGCCTGAGC AGACAGGGGC TGATGCTGCA GAAGATGAGG AAGTGGATGT CACCAGCGTG 
GACCCTATTG CTGCCTTCTG TAGCAGTGAT GAAGAGCTGG AAGATTCAAA GGCTCTATTG 
TATTTACCCA TTGCCCCTGA GGTAGAAGAC CCAGAAGAAA ATCCTTACGG CCCCCCACCG 
GATGCAGTCC AAACCTCCTT GATGGATGAA GGGGCTAGTT CAGAGAAGAA GAGGCAGTCC 
TCAGCAGATG GGTCCCAGCC ACCTAAGAAG AAACCCAAAA CAACCAATAT AGAACTTCAA 
GGAGTACCAA ATGATGAAGT CCATCCACTA CTGGGTGTGA AGGGGGATGG CAAATCCAAG 
AAGAAGCAAG CAGGCCGGCC TAAAGGATCA AAAGGTAAAG AGAAAGATTC TCCATTTAAA 
CCGAAACTCT ACAAAGGGGA CAGAGGTTTA CCTCTGGAAG GATCAGCGAA GGGTAAAGTG 
CAGGCGGAAC TCAGCCAGCC CTTGACAGGA GGAGCAATCT CAGAACTGTT ATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_011508135.1
CDS	143..1756
Translation	MNLELLESFGQNYPEEADGTLDCISMALTCTFNRWGTLLAVGCNDGRIVIWDFLTRGIAKIISAHIHPVCSLCWSRDGHKLVSASTDNIVSQWDVLSGDCDQRFRFPSPILKVQYHPRDQNKVLVCPMKSAPVMLTLSDSKHVVLPVDDDSDLNVVASFDRRGEYIYTGNAKGKILVLKTDSQDLVASFRVTTGTSNTTAIKSIEFARKGSCFLINTADRIIRVYDGREILTCGRDGEPEPMQKLQDLVNRTPWKKCCFSGDGEYIVAGSARQHALYIWEKSIGNLVKILHGTRGELLLDVAWHPVRPIIASISSGVVSIWAQNQVENWSAFAPDFKELDENVEYEERESEFDIEDEDKSEPEQTGADAAEDEEVDVTSVDPIAAFCSSDEELEDSKALLYLPIAPEVEDPEENPYGPPPDAVQTSLMDEGASSEKKRQSSADGSQPPKKKPKTTNIELQGVPNDEVHPLLGVKGDGKSKKKQAGRPKGSKGKEKDSPFKPKLYKGDRGLPLEGSAKGKVQAELSQPLTGGAISELL

Target ORF information:

RefSeq Version	XM_011509833.3
Organism	Homo sapiens(human)
Definition	Homo sapiens RB binding protein 5, histone lysine methyltransferase complex subunit (RBBP5), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_011509833.3

ORF Insert Sequence:

ATGAACCTCG AGTTGCTGGA GTCCTTTGGG CAGAACTATC CAGAGGAAGC TGATGGAACT 
TTGGATTGTA TCAGCATGGC TTTGACTTGC ACCTTTAACA GGTGGGGCAC ACTGCTTGCA 
GTTGGCTGTA ATGATGGCCG AATTGTCATC TGGGATTTCT TGACAAGAGG CATTGCTAAA 
ATAATTAGTG CACACATCCA TCCAGTGTGT TCTTTATGCT GGAGCCGAGA TGGTCATAAA 
CTCGTGAGTG CTTCCACTGA TAACATAGTG TCACAGTGGG ATGTTCTTTC AGGCGACTGT 
GACCAGAGGT TTCGATTCCC TTCACCCATC TTAAAAGTCC AATATCATCC ACGAGATCAG 
AACAAGGTTC TCGTGTGTCC CATGAAATCT GCTCCTGTCA TGTTGACCCT TTCAGATTCC 
AAACATGTTG TTCTGCCGGT GGACGATGAC TCCGATTTGA ACGTTGTGGC ATCTTTTGAT 
AGGCGAGGGG AATATATTTA TACGGGAAAC GCAAAAGGCA AGATTTTGGT CCTAAAAACA 
GATTCTCAGG ATCTTGTTGC TTCCTTCAGA GTGACAACTG GAACAAGCAA TACCACAGCC 
ATTAAGTCAA TTGAGTTTGC CCGGAAGGGG AGTTGCTTTT TAATTAACAC GGCAGATCGA 
ATAATCAGAG TTTATGATGG CAGAGAAATC TTAACATGTG GAAGAGATGG AGAGCCTGAA 
CCTATGCAGA AATTGCAGGA TTTGGTGAAT AGGACCCCAT GGAAGAAATG TTGTTTCTCT 
GGGGATGGGG AATACATCGT GGCAGGTTCT GCCCGGCAGC ATGCCCTGTA CATCTGGGAG 
AAGAGCATTG GCAACCTGGT GAAGATTCTC CATGGGACGA GAGGAGAACT CCTCTTGGAT 
GTAGCTTGGC ATCCTGTTCG ACCCATCATA GCATCCATTT CCAGTGGAGT GGTATCTATC 
TGGGCACAGA ATCAAGTAGA AAACTGGAGT GCATTTGCAC CAGACTTCAA AGAATTGGAT 
GAAAATGTAG AATACGAAGA AAGGGAATCA GAGTTTGATA TTGAAGATGA AGATAAGAGT 
GAGCCTGAGC AGACAGGGGC TGATGCTGCA GAAGATGAGG AAGTGGATGT CACCAGCGTG 
GACCCTATTG CTGCCTTCTG TAGCAGTGAT GAAGAGCTGG AAGATTCAAA GGCTCTATTG 
TATTTACCCA TTGCCCCTGA GGTAGAAGAC CCAGAAGAAA ATCCTTACGG CCCCCCACCG 
GATGCAGTCC AAACCTCCTT GATGGATGAA GGGGCTAGTT CAGAGAAGAA GAGGCAGTCC 
TCAGCAGATG GGTCCCAGCC ACCTAAGAAG AAACCCAAAA CAACCAATAT AGAACTTCAA 
GGAGTACCAA ATGATGAAGT CCATCCACTA CTGGGTGTGA AGGGGGATGG CAAATCCAAG 
AAGAAGCAAG CAGGCCGGCC TAAAGGATCA AAAGGTAAAG AGAAAGATTC TCCATTTAAA 
CCGAAACTCT ACAAAGGGGA CAGAGGTTTA CCTCTGGAAG GATCAGCGAA GGGTAAAGTG 
CAGGCGGAAC TCAGCCAGCC CTTGACAGGA GGAGCAATCT CAGAACTGTT ATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RBBP5 ( XM_011509833.2 ) cDNA ORF clone, Homo sapiens(human) -> XP_011508135.1 Homo sapiens retinoblastoma binding protein 5 (RBBP5), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OHu60214
Clone ID Related Accession (Same CDS sequence)	XM_011509833.3 , XM_011509833.2
Accession Version	XM_011509833.2	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1614bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-06-05
Organism	Homo sapiens(human)
Product	retinoblastoma-binding protein 5 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000001.11) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 6, 2016 this sequence version replaced XM_011509833.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Homo sapiens Annotation Release 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGAACCTCG AGTTGCTGGA GTCCTTTGGG CAGAACTATC CAGAGGAAGC TGATGGAACT 
TTGGATTGTA TCAGCATGGC TTTGACTTGC ACCTTTAACA GGTGGGGCAC ACTGCTTGCA 
GTTGGCTGTA ATGATGGCCG AATTGTCATC TGGGATTTCT TGACAAGAGG CATTGCTAAA 
ATAATTAGTG CACACATCCA TCCAGTGTGT TCTTTATGCT GGAGCCGAGA TGGTCATAAA 
CTCGTGAGTG CTTCCACTGA TAACATAGTG TCACAGTGGG ATGTTCTTTC AGGCGACTGT 
GACCAGAGGT TTCGATTCCC TTCACCCATC TTAAAAGTCC AATATCATCC ACGAGATCAG 
AACAAGGTTC TCGTGTGTCC CATGAAATCT GCTCCTGTCA TGTTGACCCT TTCAGATTCC 
AAACATGTTG TTCTGCCGGT GGACGATGAC TCCGATTTGA ACGTTGTGGC ATCTTTTGAT 
AGGCGAGGGG AATATATTTA TACGGGAAAC GCAAAAGGCA AGATTTTGGT CCTAAAAACA 
GATTCTCAGG ATCTTGTTGC TTCCTTCAGA GTGACAACTG GAACAAGCAA TACCACAGCC 
ATTAAGTCAA TTGAGTTTGC CCGGAAGGGG AGTTGCTTTT TAATTAACAC GGCAGATCGA 
ATAATCAGAG TTTATGATGG CAGAGAAATC TTAACATGTG GAAGAGATGG AGAGCCTGAA 
CCTATGCAGA AATTGCAGGA TTTGGTGAAT AGGACCCCAT GGAAGAAATG TTGTTTCTCT 
GGGGATGGGG AATACATCGT GGCAGGTTCT GCCCGGCAGC ATGCCCTGTA CATCTGGGAG 
AAGAGCATTG GCAACCTGGT GAAGATTCTC CATGGGACGA GAGGAGAACT CCTCTTGGAT 
GTAGCTTGGC ATCCTGTTCG ACCCATCATA GCATCCATTT CCAGTGGAGT GGTATCTATC 
TGGGCACAGA ATCAAGTAGA AAACTGGAGT GCATTTGCAC CAGACTTCAA AGAATTGGAT 
GAAAATGTAG AATACGAAGA AAGGGAATCA GAGTTTGATA TTGAAGATGA AGATAAGAGT 
GAGCCTGAGC AGACAGGGGC TGATGCTGCA GAAGATGAGG AAGTGGATGT CACCAGCGTG 
GACCCTATTG CTGCCTTCTG TAGCAGTGAT GAAGAGCTGG AAGATTCAAA GGCTCTATTG 
TATTTACCCA TTGCCCCTGA GGTAGAAGAC CCAGAAGAAA ATCCTTACGG CCCCCCACCG 
GATGCAGTCC AAACCTCCTT GATGGATGAA GGGGCTAGTT CAGAGAAGAA GAGGCAGTCC 
TCAGCAGATG GGTCCCAGCC ACCTAAGAAG AAACCCAAAA CAACCAATAT AGAACTTCAA 
GGAGTACCAA ATGATGAAGT CCATCCACTA CTGGGTGTGA AGGGGGATGG CAAATCCAAG 
AAGAAGCAAG CAGGCCGGCC TAAAGGATCA AAAGGTAAAG AGAAAGATTC TCCATTTAAA 
CCGAAACTCT ACAAAGGGGA CAGAGGTTTA CCTCTGGAAG GATCAGCGAA GGGTAAAGTG 
CAGGCGGAAC TCAGCCAGCC CTTGACAGGA GGAGCAATCT CAGAACTGTT ATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_011508135.1
CDS	148..1761
Translation	MNLELLESFGQNYPEEADGTLDCISMALTCTFNRWGTLLAVGCNDGRIVIWDFLTRGIAKIISAHIHPVCSLCWSRDGHKLVSASTDNIVSQWDVLSGDCDQRFRFPSPILKVQYHPRDQNKVLVCPMKSAPVMLTLSDSKHVVLPVDDDSDLNVVASFDRRGEYIYTGNAKGKILVLKTDSQDLVASFRVTTGTSNTTAIKSIEFARKGSCFLINTADRIIRVYDGREILTCGRDGEPEPMQKLQDLVNRTPWKKCCFSGDGEYIVAGSARQHALYIWEKSIGNLVKILHGTRGELLLDVAWHPVRPIIASISSGVVSIWAQNQVENWSAFAPDFKELDENVEYEERESEFDIEDEDKSEPEQTGADAAEDEEVDVTSVDPIAAFCSSDEELEDSKALLYLPIAPEVEDPEENPYGPPPDAVQTSLMDEGASSEKKRQSSADGSQPPKKKPKTTNIELQGVPNDEVHPLLGVKGDGKSKKKQAGRPKGSKGKEKDSPFKPKLYKGDRGLPLEGSAKGKVQAELSQPLTGGAISELL

Target ORF information:

RefSeq Version	XM_011509833.2
Organism	Homo sapiens(human)
Definition	Homo sapiens retinoblastoma binding protein 5 (RBBP5), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_011509833.2

ORF Insert Sequence:

ATGAACCTCG AGTTGCTGGA GTCCTTTGGG CAGAACTATC CAGAGGAAGC TGATGGAACT 
TTGGATTGTA TCAGCATGGC TTTGACTTGC ACCTTTAACA GGTGGGGCAC ACTGCTTGCA 
GTTGGCTGTA ATGATGGCCG AATTGTCATC TGGGATTTCT TGACAAGAGG CATTGCTAAA 
ATAATTAGTG CACACATCCA TCCAGTGTGT TCTTTATGCT GGAGCCGAGA TGGTCATAAA 
CTCGTGAGTG CTTCCACTGA TAACATAGTG TCACAGTGGG ATGTTCTTTC AGGCGACTGT 
GACCAGAGGT TTCGATTCCC TTCACCCATC TTAAAAGTCC AATATCATCC ACGAGATCAG 
AACAAGGTTC TCGTGTGTCC CATGAAATCT GCTCCTGTCA TGTTGACCCT TTCAGATTCC 
AAACATGTTG TTCTGCCGGT GGACGATGAC TCCGATTTGA ACGTTGTGGC ATCTTTTGAT 
AGGCGAGGGG AATATATTTA TACGGGAAAC GCAAAAGGCA AGATTTTGGT CCTAAAAACA 
GATTCTCAGG ATCTTGTTGC TTCCTTCAGA GTGACAACTG GAACAAGCAA TACCACAGCC 
ATTAAGTCAA TTGAGTTTGC CCGGAAGGGG AGTTGCTTTT TAATTAACAC GGCAGATCGA 
ATAATCAGAG TTTATGATGG CAGAGAAATC TTAACATGTG GAAGAGATGG AGAGCCTGAA 
CCTATGCAGA AATTGCAGGA TTTGGTGAAT AGGACCCCAT GGAAGAAATG TTGTTTCTCT 
GGGGATGGGG AATACATCGT GGCAGGTTCT GCCCGGCAGC ATGCCCTGTA CATCTGGGAG 
AAGAGCATTG GCAACCTGGT GAAGATTCTC CATGGGACGA GAGGAGAACT CCTCTTGGAT 
GTAGCTTGGC ATCCTGTTCG ACCCATCATA GCATCCATTT CCAGTGGAGT GGTATCTATC 
TGGGCACAGA ATCAAGTAGA AAACTGGAGT GCATTTGCAC CAGACTTCAA AGAATTGGAT 
GAAAATGTAG AATACGAAGA AAGGGAATCA GAGTTTGATA TTGAAGATGA AGATAAGAGT 
GAGCCTGAGC AGACAGGGGC TGATGCTGCA GAAGATGAGG AAGTGGATGT CACCAGCGTG 
GACCCTATTG CTGCCTTCTG TAGCAGTGAT GAAGAGCTGG AAGATTCAAA GGCTCTATTG 
TATTTACCCA TTGCCCCTGA GGTAGAAGAC CCAGAAGAAA ATCCTTACGG CCCCCCACCG 
GATGCAGTCC AAACCTCCTT GATGGATGAA GGGGCTAGTT CAGAGAAGAA GAGGCAGTCC 
TCAGCAGATG GGTCCCAGCC ACCTAAGAAG AAACCCAAAA CAACCAATAT AGAACTTCAA 
GGAGTACCAA ATGATGAAGT CCATCCACTA CTGGGTGTGA AGGGGGATGG CAAATCCAAG 
AAGAAGCAAG CAGGCCGGCC TAAAGGATCA AAAGGTAAAG AGAAAGATTC TCCATTTAAA 
CCGAAACTCT ACAAAGGGGA CAGAGGTTTA CCTCTGGAAG GATCAGCGAA GGGTAAAGTG 
CAGGCGGAAC TCAGCCAGCC CTTGACAGGA GGAGCAATCT CAGAACTGTT ATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Somatic cancer mutations in the MLL1 histone methyltransferase modulate its enzymatic activity and dependence on the WDR5/RBBP5/ASH2L complex.
Molecular oncology11(4)373-387(2017 Apr)
Weirich S,Kudithipudi S,Jeltsch A

A High-Density Map for Navigating the Human Polycomb Complexome.
Cell reports17(2)583-595(2016 10)
Hauri S,Comoglio F,Seimiya M,Gerstung M,Glatter T,Hansen K,Aebersold R,Paro R,Gstaiger M,Beisel C

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RBBP5 cDNA ORF clone, Homo sapiens(human)

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Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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