KCNK15 cDNA ORF clone, Homo sapiens(human)
| Gene Symbol | KCNK15 |
| Entrez Gene ID | 60598 |
| Full Name | potassium two pore domain channel subfamily K member 15 |
| Synonyms | K2p15.1,KCNK11,KCNK14,KT3.3,TASK-5,TASK5,dJ781B1.1 |
| General protein information |
|
| Gene Type | protein-coding |
| Organism | Homo sapiens(human) |
| Genome | |
| Summary | This gene encodes one of the members of the superfamily of potassium channel proteins containing two pore-forming P domains. The product of this gene has not been shown to be a functional channel, however, it may require other non-pore-forming proteins for activity. [provided by RefSeq, Jul 2008]. |
| Disorder MIM: |
mRNA and Protein(s)
| mRNA | Protein | Name |
|---|---|---|
| NM_022358.3 | NP_071753.2 | potassium channel subfamily K member 15 precursor |
| XM_017028003.1 | XP_016883492.1 | potassium channel subfamily K member 15 isoform X1 |
| Homo sapiens (human) | KCNK15 | NP_071753.2 |
| Canis lupus familiaris (dog) | KCNK15 | XP_543011.2 |
| Mus musculus (house mouse) | Kcnk15 | NP_001025463.1 |
| Danio rerio (zebrafish) | kcnk15 | NP_001104701.1 |
| Rattus norvegicus (Norway rat) | Kcnk15 | NP_570826.1 |
| Pan troglodytes (chimpanzee) | KCNK15 | XP_001152552.1 |
| Bos taurus (cattle) | KCNK15 | NP_001193475.1 |
Related articles in PubMed
Novel genetic loci identified for the pathophysiology of childhood obesity in the Hispanic population.
Comuzzie AG, Cole SA, Laston SL, Voruganti VS, Haack K, Gibbs RA, Butte NF
PloS one7(12)e51954(2012)
International Union of Pharmacology. LV. Nomenclature and molecular relationships of two-P potassium channels.
Goldstein SA, Bayliss DA, Kim D, Lesage F, Plant LD, Rajan S
Pharmacological reviews57(4)527-40(2005 Dec)
The DNA sequence and comparative analysis of human chromosome 20.
Deloukas P, Matthews LH, Ashurst J, Burton J, Gilbert JG, Jones M, Stavrides G, Almeida JP, Babbage AK, Bagguley CL, Bailey J, Barlow KF, Bates KN, Beard LM, Beare DM, Beasley OP, Bird CP, Blakey SE, Bridgeman AM, Brown AJ, Buck D, Burrill W, Butler AP, Carder C, Carter NP, Chapman JC, Clamp M, Clark G, Clark LN, Clark SY, Clee CM, Clegg S, Cobley VE, Collier RE, Connor R, Corby NR, Coulson A, Coville GJ, Deadman R, Dhami P, Dunn M, Ellington AG, Frankland JA, Fraser A, French L, Garner P, Grafham DV, Griffiths C, Griffiths MN, Gwilliam R, Hall RE, Hammond S, Harley JL, Heath PD, Ho S, Holden JL, Howden PJ, Huckle E, Hunt AR, Hunt SE, Jekosch K, Johnson CM, Johnson D, Kay MP, Kimberley AM, King A, Knights A, Laird GK, Lawlor S, Lehvaslaiho MH, Leversha M, Lloyd C, Lloyd DM, Lovell JD, Marsh VL, Martin SL, McConnachie LJ, McLay K, McMurray AA, Milne S, Mistry D, Moore MJ, Mullikin JC, Nickerson T, Oliver K, Parker A, Patel R, Pearce TA, Peck AI, Phillimore BJ, Prathalingam SR, Plumb RW, Ramsay H, Rice CM, Ross MT, Scott CE, Sehra HK, Shownkeen R, Sims S, Skuce CD, Smith ML, Soderlund C, Steward CA, Sulston JE, Swann M, Sycamore N, Taylor R, Tee L, Thomas DW, Thorpe A, Tracey A, Tromans AC, Vaudin M, Wall M, Wallis JM, Whitehead SL, Whittaker P, Willey DL, Williams L, Williams SA, Wilming L, Wray PW, Hubbard T, Durbin RM, Bentley DR, Beck S, Rogers J
Nature414(6866)865-71(2001 Dec 20-27)
Expression pattern in brain of TASK-1, TASK-3, and a tandem pore domain K(+) channel subunit, TASK-5, associated with the central auditory nervous system.
Karschin C, Wischmeyer E, Preisig-M?ller R, Rajan S, Derst C, Grzeschik KH, Daut J, Karschin A
Molecular and cellular neurosciences18(6)632-48(2001 Dec)
TASK-5, a novel member of the tandem pore K+ channel family.
Ashmole I, Goodwin PA, Stanfield PR
Pflugers Archiv : European journal of physiology442(6)828-33(2001 Sep)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
The following KCNK15 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the KCNK15 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
| CloneID | OHu32340 |
|
| Clone ID Related Accession (Same CDS sequence) | NM_022358.3 | |
| Accession Version | NM_022358.3 Latest version! | Documents for ORF clone product in default vector |
| Sequence Information | ORF Nucleotide Sequence (Length: 993bp) Protein sequence SNP |
|
| Vector | pcDNA3.1+/C-(K)DYK or customized vector |  User Manual |
| Clone information | Clone Map | MSDS |
| Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | COA |
| ORF Insert Method | CloneEZ™ Seamless cloning technology | |
| Insert Structure | linear | |
| Update Date | 2017-10-02 | |
| Organism | Homo sapiens(human) | |
| Product | potassium channel subfamily K member 15 precursor | |
| Comment | Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AF257081.1, AF294351.1 and BC082981.1. On May 19, 2011 this sequence version replaced NM_022358.2. ##Evidence-Data-START## Transcript exon combination :: AF257081.1, AF294350.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1966682, SAMEA1968189 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: full length. | |
1 | ATGCGGAGGC CGAGCGTGCG CGCGGCCGGG CTGGTCCTGT GCACCCTGTG TTACCTGCTG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
| RefSeq | NP_071753.2 |
| CDS | 65..1057 |
| Misc Feature(1) | 89..151 |
| Misc Feature(2) | <293..460 |
| Misc Feature(3) | 386..448 |
| Misc Feature(4) | 539..601 |
| Misc Feature(5) | 590..793 |
| Misc Feature(6) | 731..793 |
| Exon (1) | 1..347 |
| Exon (2) | 348..2532 |
| Translation |
Target ORF information:
Target ORF information:
|
 NM_022358.3 |
ORF Insert Sequence:
1 | ATGCGGAGGC CGAGCGTGCG CGCGGCCGGG CTGGTCCTGT GCACCCTGTG TTACCTGCTG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
| CloneID | OHu93106 | |
| Clone ID Related Accession (Same CDS sequence) | XM_017028003.1 | |
| Accession Version | XM_017028003.1 Latest version! | Documents for ORF clone product in default vector |
| Sequence Information | ORF Nucleotide Sequence (Length: 657bp) Protein sequence SNP |
|
| Vector | pcDNA3.1+/C-(K)DYK or customized vector | User Manual |
| Clone information | Clone Map | MSDS |
| Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
| ORF Insert Method | CloneEZ™ Seamless cloning technology | |
| Insert Structure | linear | |
| Update Date | 2016-06-06 | |
| Organism | Homo sapiens(human) | |
| Product | potassium channel subfamily K member 15 isoform X1 | |
| Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000020.11) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Homo sapiens Annotation Release 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## | |
1 | ATGAACCCCG GGCAGGCGAG TGGGAGGCGG ACAGGGGAGC GGTTCTTCCG GCCCCCACCC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
| RefSeq | XP_016883492.1 |
| CDS | 97..753 |
| Translation |
Target ORF information:
Target ORF information:
|
XM_017028003.1 |
ORF Insert Sequence:
1 | ATGAACCCCG GGCAGGCGAG TGGGAGGCGG ACAGGGGAGC GGTTCTTCCG GCCCCCACCC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
 |
Novel genetic loci identified for the pathophysiology of childhood obesity in the Hispanic population. |
|
International Union of Pharmacology. LV. Nomenclature and molecular relationships of two-P potassium channels. |
|
The DNA sequence and comparative analysis of human chromosome 20. |
|
Expression pattern in brain of TASK-1, TASK-3, and a tandem pore domain K(+) channel subunit, TASK-5, associated with the central auditory nervous system. |
|
TASK-5, a novel member of the tandem pore K+ channel family. |