SH2D4A cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Gene Symbol	SH2D4A
Entrez Gene ID	63898
Full Name	SH2 domain containing 4A
Synonyms	PPP1R38,SH2A
General protein information	Preferred Names SH2 domain containing 4A Names SH2 domain-containing protein 4A protein SH(2)A protein phosphatase 1 regulatory subunit 38
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 8 Map Location: 8p21.3
Disorder MIM:	614968

mRNA and Protein(s)

mRNA	Protein	Name
XM_011544610.1	XP_011542912.1	SH2 domain-containing protein 4A isoform X1
XM_017013729.1	XP_016869218.1	SH2 domain-containing protein 4A isoform X1
NM_022071.3	NP_071354.2	SH2 domain-containing protein 4A isoform a
NM_001174160.1	NP_001167631.1	SH2 domain-containing protein 4A isoform b
NM_001174159.1	NP_001167630.1	SH2 domain-containing protein 4A isoform a
NM_022071.4	NP_071354.2	SH2 domain-containing protein 4A isoform a
NM_001363110.1	NP_001350039.1	SH2 domain-containing protein 4A isoform c
NM_001363111.1	NP_001350040.1	SH2 domain-containing protein 4A isoform c

Pathways from BioSystems

Homologies

Rattus norvegicus (Norway rat)	Sh2d4a	NP_001012048.1
Caenorhabditis elegans (roundworm)	F13B12.6	NP_741483.2
Gallus gallus (chicken)	SH2D4A	XP_420452.1
Pan troglodytes (chimpanzee)	SH2D4A	XP_001148190.1
Canis lupus familiaris (dog)	SH2D4A	XP_005629820.1
Bos taurus (cattle)	SH2D4A	XP_002698789.3
Mus musculus (house mouse)	Sh2d4a	NP_082458.1
Danio rerio (zebrafish)	sh2d4a	XP_005156517.1
Xenopus tropicalis (tropical clawed frog)	sh2d4a	NP_001072704.1
Homo sapiens (human)	SH2D4A	NP_001167630.1
	SH2D4A	XP_001099151.1

Gene Ontology
Bibliography

Related articles in PubMed

Architecture of the human interactome defines protein communities and disease networks.
Huttlin EL, Bruckner RJ, Paulo JA, Cannon JR, Ting L, Baltier K, Colby G, Gebreab F, Gygi MP, Parzen H, Szpyt J, Tam S, Zarraga G, Pontano-Vaites L, Swarup S, White AE, Schweppe DK, Rad R, Erickson BK, Obar RA, Guruharsha KG, Li K, Artavanis-Tsakonas S, Gygi SP, Harper JW
Nature545(7655)505-509(2017 05)

Systematic Analysis of Human Protein Phosphatase Interactions and Dynamics.
Yadav L, Tamene F, G??s H, van Drogen A, Katainen R, Aebersold R, Gstaiger M, Varjosalo M
Cell systems4(4)430-444.e5(2017 Apr)

Chromosome 8p tumor suppressor genes SH2D4A and SORBS3 cooperate to inhibit interleukin-6 signaling in hepatocellular carcinoma.
Ploeger C, Waldburger N, Fraas A, Goeppert B, Pusch S, Breuhahn K, Wang XW, Schirmacher P, Roessler S
Hepatology (Baltimore, Md.)64(3)828-42(2016 09)

An organelle-specific protein landscape identifies novel diseases and molecular mechanisms.
Boldt K, van Reeuwijk J, Lu Q, Koutroumpas K, Nguyen TM, Texier Y, van Beersum SE, Horn N, Willer JR, Mans DA, Dougherty G, Lamers IJ, Coene KL, Arts HH, Betts MJ, Beyer T, Bolat E, Gloeckner CJ, Haidari K, Hetterschijt L, Iaconis D, Jenkins D, Klose F, Knapp B, Latour B, Letteboer SJ, Marcelis CL, Mitic D, Morleo M, Oud MM, Riemersma M, Rix S, Terhal PA, Toedt G, van Dam TJ, de Vrieze E, Wissinger Y, Wu KM, Apic G, Beales PL, Blacque OE, Gibson TJ, Huynen MA, Katsanis N, Kremer H, Omran H, van Wijk E, Wolfrum U, Kepes F, Davis EE, Franco B, Giles RH, Ueffing M, Russell RB, Roepman R,
Nature communications711491(2016 May)

Pooled-matrix protein interaction screens using Barcode Fusion Genetics.
Yachie N, Petsalaki E, Mellor JC, Weile J, Jacob Y, Verby M, Ozturk SB, Li S, Cote AG, Mosca R, Knapp JJ, Ko M, Yu A, Gebbia M, Sahni N, Yi S, Tyagi T, Sheykhkarimli D, Roth JF, Wong C, Musa L, Snider J, Liu YC, Yu H, Braun P, Stagljar I, Hao T, Calderwood MA, Pelletier L, Aloy P, Hill DE, Vidal M, Roth FP
Molecular systems biology12(4)863(2016 Apr)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The chromosome 8p tumor suppressor genes SORBS3 and SH2D4A are physically and functionally linked and provide a molecular mechanism of inhibiting STAT3-mediated IL-6 signaling in hepatocellular carcinoma cells.
Title: Chromosome 8p tumor suppressor genes SH2D4A and SORBS3 cooperate to inhibit interleukin-6 signaling in hepatocellular carcinoma.

New evidence for SH2D4A involvement in hepatocellular carcinoma pathogenesis demonstrating for the first time its deregulation in cirrhotic nodules.
Title: SH2D4A is frequently downregulated in hepatocellular carcinoma and cirrhotic nodules.

Clinical trial of gene-disease association and gene-environment interaction. (HuGE Navigator)
Title: Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score.

SH2D4A inhibited cell proliferation by suppression of the ERalpha/PLC-gamma/PKC signaling pathway.
Title: SH2D4A regulates cell proliferation via the ERalpha/PLC-gamma/PKC pathway.

SH2D4A is dispensable for TCR signal transduction in T cells
Title: Genetic analysis of SH2D4A, a novel adapter protein related to T cell-specific adapter and adapter protein in lymphocytes of unknown function, reveals a redundant function in T cells.

The following SH2D4A gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the SH2D4A cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

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***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu16920	NM_022071.4 Latest version!	Homo sapiens SH2 domain containing 4A (SH2D4A), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$159.50-$223.30 $319.00
OHu16781	NM_001174160.1 Latest version!	Homo sapiens SH2 domain containing 4A (SH2D4A), transcript variant 3, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$223.30 $319.00
OHu16920	NM_001174159.1 Latest version!	Homo sapiens SH2 domain containing 4A (SH2D4A), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$223.30 $319.00
OHu42126	NM_001363110.1 Latest version!	Homo sapiens SH2 domain containing 4A (SH2D4A), transcript variant 4, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$223.30 $319.00
OHu42126	NM_001363111.1 Latest version!	Homo sapiens SH2 domain containing 4A (SH2D4A), transcript variant 5, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$223.30 $319.00
OHu42126	XM_011544610.1 Latest version!	Homo sapiens SH2 domain containing 4A (SH2D4A), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$223.30 $319.00
OHu42126	XM_017013729.1 Latest version!	Homo sapiens SH2 domain containing 4A (SH2D4A), transcript variant X2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$223.30 $319.00
View Old Accession Versions >>
OHu16920	NM_022071.3	Homo sapiens SH2 domain containing 4A (SH2D4A), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$223.30 $319.00
Hide Old Accession Versions >>

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

SH2D4A ( NM_022071.4 ) cDNA ORF clone, Homo sapiens(human) -> NP_071354.2 Homo sapiens SH2 domain containing 4A (SH2D4A), transcript variant 1, mRNA.

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CloneID	OHu16920
Clone ID Related Accession (Same CDS sequence)	NM_022071.3 , NM_001174159.1 , NM_022071.4
Accession Version	NM_022071.4 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1365bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-10-10
Organism	Homo sapiens(human)
Product	SH2 domain-containing protein 4A isoform a
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from DA952240.1, BC082982.1, AK024799.1 and CA418381.1. On Nov 23, 2018 this sequence version replaced NM_022071.3. Transcript Variant: This variant (1) represents the longest transcript and encodes the longer isoform (a). Variants 1 and 2 both encode the same isoform (a). Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1803611.38707.1, SRR1660809.227735.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1968540, SAMEA1968832 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000265807.8/ ENSP00000265807.3 RefSeq Select criteria :: based on conservation, expression, longest protein ##RefSeq-Attributes-END## COMPLETENESS: full length.

ATGCTGAAAC AGATACTGTC GGAGATGTAC ATAGATCCTG ATCTACTGGC AGAGCTCAGC 
GAAGAACAGA AACAGATCCT GTTCTTCAAG ATGAGAGAGG AACAGATCCG ACGATGGAAA 
GAAAGAGAAG CAGCTATGGA AAGAAAGGAG TCCCTGCCAG TGAAACCCAG ACCAAAGAAA 
GAGAATGGCA AATCGGTTCA TTGGAAACTT GGAGCTGATA AGGAAGTCTG GGTATGGGTG 
ATGGGCGAAC ACCATCTAGA TAAACCCTAT GATGTGCTCT GTAATGAAAT TATTGCTGAG 
AGGGCCCGGC TGAAAGCAGA ACAGGAGGCA GAAGAGCCCA GAAAAACTCA CTCTGAAGAA 
TTCACCAATA GCTTGAAAAC AAAATCACAG TACCATGATC TGCAGGCTCC GGATAACCAG 
CAGACTAAAG ACATCTGGAA GAAAGTGGCA GAAAAGGAGG AACTGGAGCA AGGATCGAGG 
CCAGCACCAA CCCTGGAAGA AGAGAAAATC CGATCACTCT CCAGTTCTTC AAGAAATATT 
CAACAAATGT TGGCAGATTC AATCAATCGT ATGAAGGCAT ATGCATTTCA CCAGAAGAAA 
GAATCTATGA AGAAAAAACA AGATGAAGAA ATAAATCAAA TAGAAGAAGA GAGAACGAAG 
CAGATTTGTA AGAGCTGGAA AGAAGACTCG GAATGGCAGG CATCTCTGCG AAAATCCAAA 
GCAGCTGATG AGAAGAGACG CTCCTTGGCT AAACAAGCAC GAGAAGACTA CAAGAGGTTA 
TCCCTCGGGG CCCAGAAAGG AAGAGGCGGT GAGAGGCTGC AAAGCCCCTT GCGTGTTCCG 
CAGAAACCAG AAAGACCTCC CCTTCCACCC AAGCCTCAGT TCCTAAACTC AGGGGCATAT 
CCTCAAAAAC CTCTTAGAAA TCAGGGAGTG GTGAGGACAC TGTCCAGCTC TGCCCAAGAG 
GACATCATCC GGTGGTTTAA AGAGGAGCAG CTACCACTTC GAGCGGGCTA CCAGAAAACC 
TCAGACACCA TAGCCCCCTG GTTCCATGGA ATTCTCACAC TCAAGAAAGC AAATGAACTT 
CTTCTGAGCA CAGGCATGCC CGGCAGTTTT CTCATCCGAG TCAGTGAAAG GATCAAAGGC 
TATGCCCTGT CCTATCTGTC GGAGGACGGC TGTAAACATT TCCTCATCGA TGCCTCTGCA 
GACGCCTACA GCTTCCTGGG CGTGGACCAG CTACAGCATG CCACCTTGGC GGATTTGGTG 
GAATATCACA AGGAGGAACC CATCACTTCC CTGGGGAAGG AGCTCCTTCT CTATCCCTGT 
GGTCAGCAGG ACCAGCTGCC TGACTACCTG GAGCTGTTTG AGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_071354.2
CDS	336..1700
Translation	MLKQILSEMYIDPDLLAELSEEQKQILFFKMREEQIRRWKEREAAMERKESLPVKPRPKKENGKSVHWKLGADKEVWVWVMGEHHLDKPYDVLCNEIIAERARLKAEQEAEEPRKTHSEEFTNSLKTKSQYHDLQAPDNQQTKDIWKKVAEKEELEQGSRPAPTLEEEKIRSLSSSSRNIQQMLADSINRMKAYAFHQKKESMKKKQDEEINQIEEERTKQICKSWKEDSEWQASLRKSKAADEKRRSLAKQAREDYKRLSLGAQKGRGGERLQSPLRVPQKPERPPLPPKPQFLNSGAYPQKPLRNQGVVRTLSSSAQEDIIRWFKEEQLPLRAGYQKTSDTIAPWFHGILTLKKANELLLSTGMPGSFLIRVSERIKGYALSYLSEDGCKHFLIDASADAYSFLGVDQLQHATLADLVEYHKEEPITSLGKELLLYPCGQQDQLPDYLELFE

Target ORF information:

RefSeq Version	NM_022071.4
Organism	Homo sapiens(human)
Definition	Homo sapiens SH2 domain containing 4A (SH2D4A), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_022071.4

ORF Insert Sequence:

ATGCTGAAAC AGATACTGTC GGAGATGTAC ATAGATCCTG ATCTACTGGC AGAGCTCAGC 
GAAGAACAGA AACAGATCCT GTTCTTCAAG ATGAGAGAGG AACAGATCCG ACGATGGAAA 
GAAAGAGAAG CAGCTATGGA AAGAAAGGAG TCCCTGCCAG TGAAACCCAG ACCAAAGAAA 
GAGAATGGCA AATCGGTTCA TTGGAAACTT GGAGCTGATA AGGAAGTCTG GGTATGGGTG 
ATGGGCGAAC ACCATCTAGA TAAACCCTAT GATGTGCTCT GTAATGAAAT TATTGCTGAG 
AGGGCCCGGC TGAAAGCAGA ACAGGAGGCA GAAGAGCCCA GAAAAACTCA CTCTGAAGAA 
TTCACCAATA GCTTGAAAAC AAAATCACAG TACCATGATC TGCAGGCTCC GGATAACCAG 
CAGACTAAAG ACATCTGGAA GAAAGTGGCA GAAAAGGAGG AACTGGAGCA AGGATCGAGG 
CCAGCACCAA CCCTGGAAGA AGAGAAAATC CGATCACTCT CCAGTTCTTC AAGAAATATT 
CAACAAATGT TGGCAGATTC AATCAATCGT ATGAAGGCAT ATGCATTTCA CCAGAAGAAA 
GAATCTATGA AGAAAAAACA AGATGAAGAA ATAAATCAAA TAGAAGAAGA GAGAACGAAG 
CAGATTTGTA AGAGCTGGAA AGAAGACTCG GAATGGCAGG CATCTCTGCG AAAATCCAAA 
GCAGCTGATG AGAAGAGACG CTCCTTGGCT AAACAAGCAC GAGAAGACTA CAAGAGGTTA 
TCCCTCGGGG CCCAGAAAGG AAGAGGCGGT GAGAGGCTGC AAAGCCCCTT GCGTGTTCCG 
CAGAAACCAG AAAGACCTCC CCTTCCACCC AAGCCTCAGT TCCTAAACTC AGGGGCATAT 
CCTCAAAAAC CTCTTAGAAA TCAGGGAGTG GTGAGGACAC TGTCCAGCTC TGCCCAAGAG 
GACATCATCC GGTGGTTTAA AGAGGAGCAG CTACCACTTC GAGCGGGCTA CCAGAAAACC 
TCAGACACCA TAGCCCCCTG GTTCCATGGA ATTCTCACAC TCAAGAAAGC AAATGAACTT 
CTTCTGAGCA CAGGCATGCC CGGCAGTTTT CTCATCCGAG TCAGTGAAAG GATCAAAGGC 
TATGCCCTGT CCTATCTGTC GGAGGACGGC TGTAAACATT TCCTCATCGA TGCCTCTGCA 
GACGCCTACA GCTTCCTGGG CGTGGACCAG CTACAGCATG CCACCTTGGC GGATTTGGTG 
GAATATCACA AGGAGGAACC CATCACTTCC CTGGGGAAGG AGCTCCTTCT CTATCCCTGT 
GGTCAGCAGG ACCAGCTGCC TGACTACCTG GAGCTGTTTG AGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

SH2D4A ( NM_001174160.1 ) cDNA ORF clone, Homo sapiens(human) -> NP_001167631.1 Homo sapiens SH2 domain containing 4A (SH2D4A), transcript variant 3, mRNA.

Price & Availability↑

CloneID	OHu16781
Clone ID Related Accession (Same CDS sequence)	NM_001174160.1
Accession Version	NM_001174160.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1230bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-10-09
Organism	Homo sapiens(human)
Product	SH2 domain-containing protein 4A isoform b
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from DA952240.1, AK293301.1, AK024799.1 and CA418381.1. Transcript Variant: This variant (3) differs in the 5' UTR and coding sequence compared to variant 1. The resulting isoform (b) has a shorter and distinct N-terminus compared to isoform a. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AK293301.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2142348, SAMEA2142586 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGTGGCGGG TGATCGAGCC ACCCTGCCCA GGGGCGCCCA GCACTGAGAA TGGCAAATCG 
GTTCATTGGA AACTTGGAGC TGATAAGGAA GTCTGGGTAT GGGTGATGGG CGAACACCAT 
CTAGATAAAC CCTATGATGT GCTCTGTAAT GAAATTATTG CTGAGAGGGC CCGGCTGAAA 
GCAGAACAGG AGGCAGAAGA GCCCAGAAAA ACTCACTCTG AAGAATTCAC CAATAGCTTG 
AAAACAAAAT CACAGTACCA TGATCTGCAG GCTCCGGATA ACCAGCAGAC TAAAGACATC 
TGGAAGAAAG TGGCAGAAAA GGAGGAACTG GAGCAAGGAT CGAGGCCAGC ACCAACCCTG 
GAAGAAGAGA AAATCCGATC ACTCTCCAGT TCTTCAAGAA ATATTCAACA AATGTTGGCA 
GATTCAATCA ATCGTATGAA GGCATATGCA TTTCACCAGA AGAAAGAATC TATGAAGAAA 
AAACAAGATG AAGAAATAAA TCAAATAGAA GAAGAGAGAA CGAAGCAGAT TTGTAAGAGC 
TGGAAAGAAG ACTCGGAATG GCAGGCATCT CTGCGAAAAT CCAAAGCAGC TGATGAGAAG 
AGACGCTCCT TGGCTAAACA AGCACGAGAA GACTACAAGA GGTTATCCCT CGGGGCCCAG 
AAAGGAAGAG GCGGTGAGAG GCTGCAAAGC CCCTTGCGTG TTCCGCAGAA ACCAGAAAGA 
CCTCCCCTTC CACCCAAGCC TCAGTTCCTA AACTCAGGGG CATATCCTCA AAAACCTCTT 
AGAAATCAGG GAGTGGTGAG GACACTGTCC AGCTCTGCCC AAGAGGACAT CATCCGGTGG 
TTTAAAGAGG AGCAGCTACC ACTTCGAGCG GGCTACCAGA AAACCTCAGA CACCATAGCC 
CCCTGGTTCC ATGGAATTCT CACACTCAAG AAAGCAAATG AACTTCTTCT GAGCACAGGC 
ATGCCCGGCA GTTTTCTCAT CCGAGTCAGT GAAAGGATCA AAGGCTATGC CCTGTCCTAT 
CTGTCGGAGG ACGGCTGTAA ACATTTCCTC ATCGATGCCT CTGCAGACGC CTACAGCTTC 
CTGGGCGTGG ACCAGCTACA GCATGCCACC TTGGCGGATT TGGTGGAATA TCACAAGGAG 
GAACCCATCA CTTCCCTGGG GAAGGAGCTC CTTCTCTATC CCTGTGGTCA GCAGGACCAG 
CTGCCTGACT ACCTGGAGCT GTTTGAGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001167631.1
CDS	209..1438
Translation	MWRVIEPPCPGAPSTENGKSVHWKLGADKEVWVWVMGEHHLDKPYDVLCNEIIAERARLKAEQEAEEPRKTHSEEFTNSLKTKSQYHDLQAPDNQQTKDIWKKVAEKEELEQGSRPAPTLEEEKIRSLSSSSRNIQQMLADSINRMKAYAFHQKKESMKKKQDEEINQIEEERTKQICKSWKEDSEWQASLRKSKAADEKRRSLAKQAREDYKRLSLGAQKGRGGERLQSPLRVPQKPERPPLPPKPQFLNSGAYPQKPLRNQGVVRTLSSSAQEDIIRWFKEEQLPLRAGYQKTSDTIAPWFHGILTLKKANELLLSTGMPGSFLIRVSERIKGYALSYLSEDGCKHFLIDASADAYSFLGVDQLQHATLADLVEYHKEEPITSLGKELLLYPCGQQDQLPDYLELFE

Target ORF information:

RefSeq Version	NM_001174160.1
Organism	Homo sapiens(human)
Definition	Homo sapiens SH2 domain containing 4A (SH2D4A), transcript variant 3, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001174160.1

ORF Insert Sequence:

ATGTGGCGGG TGATCGAGCC ACCCTGCCCA GGGGCGCCCA GCACTGAGAA TGGCAAATCG 
GTTCATTGGA AACTTGGAGC TGATAAGGAA GTCTGGGTAT GGGTGATGGG CGAACACCAT 
CTAGATAAAC CCTATGATGT GCTCTGTAAT GAAATTATTG CTGAGAGGGC CCGGCTGAAA 
GCAGAACAGG AGGCAGAAGA GCCCAGAAAA ACTCACTCTG AAGAATTCAC CAATAGCTTG 
AAAACAAAAT CACAGTACCA TGATCTGCAG GCTCCGGATA ACCAGCAGAC TAAAGACATC 
TGGAAGAAAG TGGCAGAAAA GGAGGAACTG GAGCAAGGAT CGAGGCCAGC ACCAACCCTG 
GAAGAAGAGA AAATCCGATC ACTCTCCAGT TCTTCAAGAA ATATTCAACA AATGTTGGCA 
GATTCAATCA ATCGTATGAA GGCATATGCA TTTCACCAGA AGAAAGAATC TATGAAGAAA 
AAACAAGATG AAGAAATAAA TCAAATAGAA GAAGAGAGAA CGAAGCAGAT TTGTAAGAGC 
TGGAAAGAAG ACTCGGAATG GCAGGCATCT CTGCGAAAAT CCAAAGCAGC TGATGAGAAG 
AGACGCTCCT TGGCTAAACA AGCACGAGAA GACTACAAGA GGTTATCCCT CGGGGCCCAG 
AAAGGAAGAG GCGGTGAGAG GCTGCAAAGC CCCTTGCGTG TTCCGCAGAA ACCAGAAAGA 
CCTCCCCTTC CACCCAAGCC TCAGTTCCTA AACTCAGGGG CATATCCTCA AAAACCTCTT 
AGAAATCAGG GAGTGGTGAG GACACTGTCC AGCTCTGCCC AAGAGGACAT CATCCGGTGG 
TTTAAAGAGG AGCAGCTACC ACTTCGAGCG GGCTACCAGA AAACCTCAGA CACCATAGCC 
CCCTGGTTCC ATGGAATTCT CACACTCAAG AAAGCAAATG AACTTCTTCT GAGCACAGGC 
ATGCCCGGCA GTTTTCTCAT CCGAGTCAGT GAAAGGATCA AAGGCTATGC CCTGTCCTAT 
CTGTCGGAGG ACGGCTGTAA ACATTTCCTC ATCGATGCCT CTGCAGACGC CTACAGCTTC 
CTGGGCGTGG ACCAGCTACA GCATGCCACC TTGGCGGATT TGGTGGAATA TCACAAGGAG 
GAACCCATCA CTTCCCTGGG GAAGGAGCTC CTTCTCTATC CCTGTGGTCA GCAGGACCAG 
CTGCCTGACT ACCTGGAGCT GTTTGAGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

SH2D4A ( NM_022071.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_071354.2 Homo sapiens SH2 domain containing 4A (SH2D4A), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OHu16920
Clone ID Related Accession (Same CDS sequence)	NM_022071.3 , NM_001174159.1 , NM_022071.4
Accession Version	NM_022071.3	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1365bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2017-10-01
Organism	Homo sapiens(human)
Product	SH2 domain-containing protein 4A isoform a
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from DA952240.1, BC082982.1, AK024799.1 and CA418381.1. On Mar 31, 2010 this sequence version replaced NM_022071.2. Transcript Variant: This variant (1) represents the longest transcript and encodes the longer isoform (a). Variants 1 and 2 both encode the same isoform (a). Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1803611.38707.1, SRR1660809.227735.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1968540, SAMEA1968832 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGCTGAAAC AGATACTGTC GGAGATGTAC ATAGATCCTG ATCTACTGGC AGAGCTCAGC 
GAAGAACAGA AACAGATCCT GTTCTTCAAG ATGAGAGAGG AACAGATCCG ACGATGGAAA 
GAAAGAGAAG CAGCTATGGA AAGAAAGGAG TCCCTGCCAG TGAAACCCAG ACCAAAGAAA 
GAGAATGGCA AATCGGTTCA TTGGAAACTT GGAGCTGATA AGGAAGTCTG GGTATGGGTG 
ATGGGCGAAC ACCATCTAGA TAAACCCTAT GATGTGCTCT GTAATGAAAT TATTGCTGAG 
AGGGCCCGGC TGAAAGCAGA ACAGGAGGCA GAAGAGCCCA GAAAAACTCA CTCTGAAGAA 
TTCACCAATA GCTTGAAAAC AAAATCACAG TACCATGATC TGCAGGCTCC GGATAACCAG 
CAGACTAAAG ACATCTGGAA GAAAGTGGCA GAAAAGGAGG AACTGGAGCA AGGATCGAGG 
CCAGCACCAA CCCTGGAAGA AGAGAAAATC CGATCACTCT CCAGTTCTTC AAGAAATATT 
CAACAAATGT TGGCAGATTC AATCAATCGT ATGAAGGCAT ATGCATTTCA CCAGAAGAAA 
GAATCTATGA AGAAAAAACA AGATGAAGAA ATAAATCAAA TAGAAGAAGA GAGAACGAAG 
CAGATTTGTA AGAGCTGGAA AGAAGACTCG GAATGGCAGG CATCTCTGCG AAAATCCAAA 
GCAGCTGATG AGAAGAGACG CTCCTTGGCT AAACAAGCAC GAGAAGACTA CAAGAGGTTA 
TCCCTCGGGG CCCAGAAAGG AAGAGGCGGT GAGAGGCTGC AAAGCCCCTT GCGTGTTCCG 
CAGAAACCAG AAAGACCTCC CCTTCCACCC AAGCCTCAGT TCCTAAACTC AGGGGCATAT 
CCTCAAAAAC CTCTTAGAAA TCAGGGAGTG GTGAGGACAC TGTCCAGCTC TGCCCAAGAG 
GACATCATCC GGTGGTTTAA AGAGGAGCAG CTACCACTTC GAGCGGGCTA CCAGAAAACC 
TCAGACACCA TAGCCCCCTG GTTCCATGGA ATTCTCACAC TCAAGAAAGC AAATGAACTT 
CTTCTGAGCA CAGGCATGCC CGGCAGTTTT CTCATCCGAG TCAGTGAAAG GATCAAAGGC 
TATGCCCTGT CCTATCTGTC GGAGGACGGC TGTAAACATT TCCTCATCGA TGCCTCTGCA 
GACGCCTACA GCTTCCTGGG CGTGGACCAG CTACAGCATG CCACCTTGGC GGATTTGGTG 
GAATATCACA AGGAGGAACC CATCACTTCC CTGGGGAAGG AGCTCCTTCT CTATCCCTGT 
GGTCAGCAGG ACCAGCTGCC TGACTACCTG GAGCTGTTTG AGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_071354.2
CDS	459..1823
Translation	MLKQILSEMYIDPDLLAELSEEQKQILFFKMREEQIRRWKEREAAMERKESLPVKPRPKKENGKSVHWKLGADKEVWVWVMGEHHLDKPYDVLCNEIIAERARLKAEQEAEEPRKTHSEEFTNSLKTKSQYHDLQAPDNQQTKDIWKKVAEKEELEQGSRPAPTLEEEKIRSLSSSSRNIQQMLADSINRMKAYAFHQKKESMKKKQDEEINQIEEERTKQICKSWKEDSEWQASLRKSKAADEKRRSLAKQAREDYKRLSLGAQKGRGGERLQSPLRVPQKPERPPLPPKPQFLNSGAYPQKPLRNQGVVRTLSSSAQEDIIRWFKEEQLPLRAGYQKTSDTIAPWFHGILTLKKANELLLSTGMPGSFLIRVSERIKGYALSYLSEDGCKHFLIDASADAYSFLGVDQLQHATLADLVEYHKEEPITSLGKELLLYPCGQQDQLPDYLELFE

Target ORF information:

RefSeq Version	NM_022071.3
Organism	Homo sapiens(human)
Definition	Homo sapiens SH2 domain containing 4A (SH2D4A), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_022071.3

ORF Insert Sequence:

ATGCTGAAAC AGATACTGTC GGAGATGTAC ATAGATCCTG ATCTACTGGC AGAGCTCAGC 
GAAGAACAGA AACAGATCCT GTTCTTCAAG ATGAGAGAGG AACAGATCCG ACGATGGAAA 
GAAAGAGAAG CAGCTATGGA AAGAAAGGAG TCCCTGCCAG TGAAACCCAG ACCAAAGAAA 
GAGAATGGCA AATCGGTTCA TTGGAAACTT GGAGCTGATA AGGAAGTCTG GGTATGGGTG 
ATGGGCGAAC ACCATCTAGA TAAACCCTAT GATGTGCTCT GTAATGAAAT TATTGCTGAG 
AGGGCCCGGC TGAAAGCAGA ACAGGAGGCA GAAGAGCCCA GAAAAACTCA CTCTGAAGAA 
TTCACCAATA GCTTGAAAAC AAAATCACAG TACCATGATC TGCAGGCTCC GGATAACCAG 
CAGACTAAAG ACATCTGGAA GAAAGTGGCA GAAAAGGAGG AACTGGAGCA AGGATCGAGG 
CCAGCACCAA CCCTGGAAGA AGAGAAAATC CGATCACTCT CCAGTTCTTC AAGAAATATT 
CAACAAATGT TGGCAGATTC AATCAATCGT ATGAAGGCAT ATGCATTTCA CCAGAAGAAA 
GAATCTATGA AGAAAAAACA AGATGAAGAA ATAAATCAAA TAGAAGAAGA GAGAACGAAG 
CAGATTTGTA AGAGCTGGAA AGAAGACTCG GAATGGCAGG CATCTCTGCG AAAATCCAAA 
GCAGCTGATG AGAAGAGACG CTCCTTGGCT AAACAAGCAC GAGAAGACTA CAAGAGGTTA 
TCCCTCGGGG CCCAGAAAGG AAGAGGCGGT GAGAGGCTGC AAAGCCCCTT GCGTGTTCCG 
CAGAAACCAG AAAGACCTCC CCTTCCACCC AAGCCTCAGT TCCTAAACTC AGGGGCATAT 
CCTCAAAAAC CTCTTAGAAA TCAGGGAGTG GTGAGGACAC TGTCCAGCTC TGCCCAAGAG 
GACATCATCC GGTGGTTTAA AGAGGAGCAG CTACCACTTC GAGCGGGCTA CCAGAAAACC 
TCAGACACCA TAGCCCCCTG GTTCCATGGA ATTCTCACAC TCAAGAAAGC AAATGAACTT 
CTTCTGAGCA CAGGCATGCC CGGCAGTTTT CTCATCCGAG TCAGTGAAAG GATCAAAGGC 
TATGCCCTGT CCTATCTGTC GGAGGACGGC TGTAAACATT TCCTCATCGA TGCCTCTGCA 
GACGCCTACA GCTTCCTGGG CGTGGACCAG CTACAGCATG CCACCTTGGC GGATTTGGTG 
GAATATCACA AGGAGGAACC CATCACTTCC CTGGGGAAGG AGCTCCTTCT CTATCCCTGT 
GGTCAGCAGG ACCAGCTGCC TGACTACCTG GAGCTGTTTG AGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

SH2D4A ( NM_001174159.1 ) cDNA ORF clone, Homo sapiens(human) -> NP_001167630.1 Homo sapiens SH2 domain containing 4A (SH2D4A), transcript variant 2, mRNA.

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CloneID	OHu16920
Clone ID Related Accession (Same CDS sequence)	NM_022071.3 , NM_001174159.1 , NM_022071.4
Accession Version	NM_001174159.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1365bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-10-09
Organism	Homo sapiens(human)
Product	SH2 domain-containing protein 4A isoform a
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from BC082982.1, AK024799.1 and CA418381.1. Transcript Variant: This variant (2) differs in the 5' UTR compared to variant 1. Variants 1 and 2 both encode the same isoform (a). Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC082982.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1968540, SAMEA1968832 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGCTGAAAC AGATACTGTC GGAGATGTAC ATAGATCCTG ATCTACTGGC AGAGCTCAGC 
GAAGAACAGA AACAGATCCT GTTCTTCAAG ATGAGAGAGG AACAGATCCG ACGATGGAAA 
GAAAGAGAAG CAGCTATGGA AAGAAAGGAG TCCCTGCCAG TGAAACCCAG ACCAAAGAAA 
GAGAATGGCA AATCGGTTCA TTGGAAACTT GGAGCTGATA AGGAAGTCTG GGTATGGGTG 
ATGGGCGAAC ACCATCTAGA TAAACCCTAT GATGTGCTCT GTAATGAAAT TATTGCTGAG 
AGGGCCCGGC TGAAAGCAGA ACAGGAGGCA GAAGAGCCCA GAAAAACTCA CTCTGAAGAA 
TTCACCAATA GCTTGAAAAC AAAATCACAG TACCATGATC TGCAGGCTCC GGATAACCAG 
CAGACTAAAG ACATCTGGAA GAAAGTGGCA GAAAAGGAGG AACTGGAGCA AGGATCGAGG 
CCAGCACCAA CCCTGGAAGA AGAGAAAATC CGATCACTCT CCAGTTCTTC AAGAAATATT 
CAACAAATGT TGGCAGATTC AATCAATCGT ATGAAGGCAT ATGCATTTCA CCAGAAGAAA 
GAATCTATGA AGAAAAAACA AGATGAAGAA ATAAATCAAA TAGAAGAAGA GAGAACGAAG 
CAGATTTGTA AGAGCTGGAA AGAAGACTCG GAATGGCAGG CATCTCTGCG AAAATCCAAA 
GCAGCTGATG AGAAGAGACG CTCCTTGGCT AAACAAGCAC GAGAAGACTA CAAGAGGTTA 
TCCCTCGGGG CCCAGAAAGG AAGAGGCGGT GAGAGGCTGC AAAGCCCCTT GCGTGTTCCG 
CAGAAACCAG AAAGACCTCC CCTTCCACCC AAGCCTCAGT TCCTAAACTC AGGGGCATAT 
CCTCAAAAAC CTCTTAGAAA TCAGGGAGTG GTGAGGACAC TGTCCAGCTC TGCCCAAGAG 
GACATCATCC GGTGGTTTAA AGAGGAGCAG CTACCACTTC GAGCGGGCTA CCAGAAAACC 
TCAGACACCA TAGCCCCCTG GTTCCATGGA ATTCTCACAC TCAAGAAAGC AAATGAACTT 
CTTCTGAGCA CAGGCATGCC CGGCAGTTTT CTCATCCGAG TCAGTGAAAG GATCAAAGGC 
TATGCCCTGT CCTATCTGTC GGAGGACGGC TGTAAACATT TCCTCATCGA TGCCTCTGCA 
GACGCCTACA GCTTCCTGGG CGTGGACCAG CTACAGCATG CCACCTTGGC GGATTTGGTG 
GAATATCACA AGGAGGAACC CATCACTTCC CTGGGGAAGG AGCTCCTTCT CTATCCCTGT 
GGTCAGCAGG ACCAGCTGCC TGACTACCTG GAGCTGTTTG AGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001167630.1
CDS	309..1673
Translation	MLKQILSEMYIDPDLLAELSEEQKQILFFKMREEQIRRWKEREAAMERKESLPVKPRPKKENGKSVHWKLGADKEVWVWVMGEHHLDKPYDVLCNEIIAERARLKAEQEAEEPRKTHSEEFTNSLKTKSQYHDLQAPDNQQTKDIWKKVAEKEELEQGSRPAPTLEEEKIRSLSSSSRNIQQMLADSINRMKAYAFHQKKESMKKKQDEEINQIEEERTKQICKSWKEDSEWQASLRKSKAADEKRRSLAKQAREDYKRLSLGAQKGRGGERLQSPLRVPQKPERPPLPPKPQFLNSGAYPQKPLRNQGVVRTLSSSAQEDIIRWFKEEQLPLRAGYQKTSDTIAPWFHGILTLKKANELLLSTGMPGSFLIRVSERIKGYALSYLSEDGCKHFLIDASADAYSFLGVDQLQHATLADLVEYHKEEPITSLGKELLLYPCGQQDQLPDYLELFE

Target ORF information:

RefSeq Version	NM_001174159.1
Organism	Homo sapiens(human)
Definition	Homo sapiens SH2 domain containing 4A (SH2D4A), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001174159.1

ORF Insert Sequence:

ATGCTGAAAC AGATACTGTC GGAGATGTAC ATAGATCCTG ATCTACTGGC AGAGCTCAGC 
GAAGAACAGA AACAGATCCT GTTCTTCAAG ATGAGAGAGG AACAGATCCG ACGATGGAAA 
GAAAGAGAAG CAGCTATGGA AAGAAAGGAG TCCCTGCCAG TGAAACCCAG ACCAAAGAAA 
GAGAATGGCA AATCGGTTCA TTGGAAACTT GGAGCTGATA AGGAAGTCTG GGTATGGGTG 
ATGGGCGAAC ACCATCTAGA TAAACCCTAT GATGTGCTCT GTAATGAAAT TATTGCTGAG 
AGGGCCCGGC TGAAAGCAGA ACAGGAGGCA GAAGAGCCCA GAAAAACTCA CTCTGAAGAA 
TTCACCAATA GCTTGAAAAC AAAATCACAG TACCATGATC TGCAGGCTCC GGATAACCAG 
CAGACTAAAG ACATCTGGAA GAAAGTGGCA GAAAAGGAGG AACTGGAGCA AGGATCGAGG 
CCAGCACCAA CCCTGGAAGA AGAGAAAATC CGATCACTCT CCAGTTCTTC AAGAAATATT 
CAACAAATGT TGGCAGATTC AATCAATCGT ATGAAGGCAT ATGCATTTCA CCAGAAGAAA 
GAATCTATGA AGAAAAAACA AGATGAAGAA ATAAATCAAA TAGAAGAAGA GAGAACGAAG 
CAGATTTGTA AGAGCTGGAA AGAAGACTCG GAATGGCAGG CATCTCTGCG AAAATCCAAA 
GCAGCTGATG AGAAGAGACG CTCCTTGGCT AAACAAGCAC GAGAAGACTA CAAGAGGTTA 
TCCCTCGGGG CCCAGAAAGG AAGAGGCGGT GAGAGGCTGC AAAGCCCCTT GCGTGTTCCG 
CAGAAACCAG AAAGACCTCC CCTTCCACCC AAGCCTCAGT TCCTAAACTC AGGGGCATAT 
CCTCAAAAAC CTCTTAGAAA TCAGGGAGTG GTGAGGACAC TGTCCAGCTC TGCCCAAGAG 
GACATCATCC GGTGGTTTAA AGAGGAGCAG CTACCACTTC GAGCGGGCTA CCAGAAAACC 
TCAGACACCA TAGCCCCCTG GTTCCATGGA ATTCTCACAC TCAAGAAAGC AAATGAACTT 
CTTCTGAGCA CAGGCATGCC CGGCAGTTTT CTCATCCGAG TCAGTGAAAG GATCAAAGGC 
TATGCCCTGT CCTATCTGTC GGAGGACGGC TGTAAACATT TCCTCATCGA TGCCTCTGCA 
GACGCCTACA GCTTCCTGGG CGTGGACCAG CTACAGCATG CCACCTTGGC GGATTTGGTG 
GAATATCACA AGGAGGAACC CATCACTTCC CTGGGGAAGG AGCTCCTTCT CTATCCCTGT 
GGTCAGCAGG ACCAGCTGCC TGACTACCTG GAGCTGTTTG AGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

SH2D4A ( NM_001363110.1 ) cDNA ORF clone, Homo sapiens(human) -> NP_001350039.1 Homo sapiens SH2 domain containing 4A (SH2D4A), transcript variant 4, mRNA.

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CloneID	OHu42126
Clone ID Related Accession (Same CDS sequence)	XM_011544610.1 , XM_017013729.1 , NM_001363110.1 , NM_001363111.1
Accession Version	NM_001363110.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1284bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-10-10
Organism	Homo sapiens(human)
Product	SH2 domain-containing protein 4A isoform c
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from DA952240.1, BC082982.1, DB183296.1, AK024799.1 and CA418381.1. On May 8, 2018 this sequence version replaced XM_011544610.1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1803614.50479.1, SRR1660809.115540.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1968540, SAMEA1968832 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGCTGAAAC AGATACTGTC GGAGATGTAC ATAGATCCTG ATCTACTGGC AGAGCTCAGC 
GAAGAACAGA AACAGATCCT GTTCTTCAAG ATGAGAGAGG AACAGATCCG ACGATGGAAA 
GAAAGAGAAG CAGCTATGGA AAGAAAGGAG TCCCTGCCAG TGAAACCCAG ACCAAAGAAA 
GAGAATGGCA AATCGGTTCA TTGGAAACTT GGAGCTGATA AGGAAGTCTG GGTATGGGTG 
ATGGGCGAAC ACCATCTAGA TAAACCCTAT GATGTGCTCT GTAATGAAAT TATTGCTGAG 
AGGGCCCGGC TGAAAGCAGA ACAGGAGGCA GAAGAGCCCA GAAAAACTCA CTCTGAAGAA 
TTCACCAATA GCTTGAAAAC AAAATCACAG TACCATGATC TGCAGGCTCC GGATAACCAG 
CAGACTAAAG ACATCTGGAA GAAAGTGGCA GAAAAGGAGG AACTGGAGCA AGGATCGAGG 
CCAGCACCAA CCCTGGAAGA AGAGAAAATC CGAAAGAAAG AATCTATGAA GAAAAAACAA 
GATGAAGAAA TAAATCAAAT AGAAGAAGAG AGAACGAAGC AGATTTGTAA GAGCTGGAAA 
GAAGACTCGG AATGGCAGGC ATCTCTGCGA AAATCCAAAG CAGCTGATGA GAAGAGACGC 
TCCTTGGCTA AACAAGCACG AGAAGACTAC AAGAGGTTAT CCCTCGGGGC CCAGAAAGGA 
AGAGGCGGTG AGAGGCTGCA AAGCCCCTTG CGTGTTCCGC AGAAACCAGA AAGACCTCCC 
CTTCCACCCA AGCCTCAGTT CCTAAACTCA GGGGCATATC CTCAAAAACC TCTTAGAAAT 
CAGGGAGTGG TGAGGACACT GTCCAGCTCT GCCCAAGAGG ACATCATCCG GTGGTTTAAA 
GAGGAGCAGC TACCACTTCG AGCGGGCTAC CAGAAAACCT CAGACACCAT AGCCCCCTGG 
TTCCATGGAA TTCTCACACT CAAGAAAGCA AATGAACTTC TTCTGAGCAC AGGCATGCCC 
GGCAGTTTTC TCATCCGAGT CAGTGAAAGG ATCAAAGGCT ATGCCCTGTC CTATCTGTCG 
GAGGACGGCT GTAAACATTT CCTCATCGAT GCCTCTGCAG ACGCCTACAG CTTCCTGGGC 
GTGGACCAGC TACAGCATGC CACCTTGGCG GATTTGGTGG AATATCACAA GGAGGAACCC 
ATCACTTCCC TGGGGAAGGA GCTCCTTCTC TATCCCTGTG GTCAGCAGGA CCAGCTGCCT 
GACTACCTGG AGCTGTTTGA GTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001350039.1
CDS	459..1742
Translation	MLKQILSEMYIDPDLLAELSEEQKQILFFKMREEQIRRWKEREAAMERKESLPVKPRPKKENGKSVHWKLGADKEVWVWVMGEHHLDKPYDVLCNEIIAERARLKAEQEAEEPRKTHSEEFTNSLKTKSQYHDLQAPDNQQTKDIWKKVAEKEELEQGSRPAPTLEEEKIRKKESMKKKQDEEINQIEEERTKQICKSWKEDSEWQASLRKSKAADEKRRSLAKQAREDYKRLSLGAQKGRGGERLQSPLRVPQKPERPPLPPKPQFLNSGAYPQKPLRNQGVVRTLSSSAQEDIIRWFKEEQLPLRAGYQKTSDTIAPWFHGILTLKKANELLLSTGMPGSFLIRVSERIKGYALSYLSEDGCKHFLIDASADAYSFLGVDQLQHATLADLVEYHKEEPITSLGKELLLYPCGQQDQLPDYLELFE

Target ORF information:

RefSeq Version	NM_001363110.1
Organism	Homo sapiens(human)
Definition	Homo sapiens SH2 domain containing 4A (SH2D4A), transcript variant 4, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001363110.1

ORF Insert Sequence:

ATGCTGAAAC AGATACTGTC GGAGATGTAC ATAGATCCTG ATCTACTGGC AGAGCTCAGC 
GAAGAACAGA AACAGATCCT GTTCTTCAAG ATGAGAGAGG AACAGATCCG ACGATGGAAA 
GAAAGAGAAG CAGCTATGGA AAGAAAGGAG TCCCTGCCAG TGAAACCCAG ACCAAAGAAA 
GAGAATGGCA AATCGGTTCA TTGGAAACTT GGAGCTGATA AGGAAGTCTG GGTATGGGTG 
ATGGGCGAAC ACCATCTAGA TAAACCCTAT GATGTGCTCT GTAATGAAAT TATTGCTGAG 
AGGGCCCGGC TGAAAGCAGA ACAGGAGGCA GAAGAGCCCA GAAAAACTCA CTCTGAAGAA 
TTCACCAATA GCTTGAAAAC AAAATCACAG TACCATGATC TGCAGGCTCC GGATAACCAG 
CAGACTAAAG ACATCTGGAA GAAAGTGGCA GAAAAGGAGG AACTGGAGCA AGGATCGAGG 
CCAGCACCAA CCCTGGAAGA AGAGAAAATC CGAAAGAAAG AATCTATGAA GAAAAAACAA 
GATGAAGAAA TAAATCAAAT AGAAGAAGAG AGAACGAAGC AGATTTGTAA GAGCTGGAAA 
GAAGACTCGG AATGGCAGGC ATCTCTGCGA AAATCCAAAG CAGCTGATGA GAAGAGACGC 
TCCTTGGCTA AACAAGCACG AGAAGACTAC AAGAGGTTAT CCCTCGGGGC CCAGAAAGGA 
AGAGGCGGTG AGAGGCTGCA AAGCCCCTTG CGTGTTCCGC AGAAACCAGA AAGACCTCCC 
CTTCCACCCA AGCCTCAGTT CCTAAACTCA GGGGCATATC CTCAAAAACC TCTTAGAAAT 
CAGGGAGTGG TGAGGACACT GTCCAGCTCT GCCCAAGAGG ACATCATCCG GTGGTTTAAA 
GAGGAGCAGC TACCACTTCG AGCGGGCTAC CAGAAAACCT CAGACACCAT AGCCCCCTGG 
TTCCATGGAA TTCTCACACT CAAGAAAGCA AATGAACTTC TTCTGAGCAC AGGCATGCCC 
GGCAGTTTTC TCATCCGAGT CAGTGAAAGG ATCAAAGGCT ATGCCCTGTC CTATCTGTCG 
GAGGACGGCT GTAAACATTT CCTCATCGAT GCCTCTGCAG ACGCCTACAG CTTCCTGGGC 
GTGGACCAGC TACAGCATGC CACCTTGGCG GATTTGGTGG AATATCACAA GGAGGAACCC 
ATCACTTCCC TGGGGAAGGA GCTCCTTCTC TATCCCTGTG GTCAGCAGGA CCAGCTGCCT 
GACTACCTGG AGCTGTTTGA GTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

SH2D4A ( NM_001363111.1 ) cDNA ORF clone, Homo sapiens(human) -> NP_001350040.1 Homo sapiens SH2 domain containing 4A (SH2D4A), transcript variant 5, mRNA.

Price & Availability↑

CloneID	OHu42126
Clone ID Related Accession (Same CDS sequence)	XM_011544610.1 , XM_017013729.1 , NM_001363110.1 , NM_001363111.1
Accession Version	NM_001363111.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1284bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-10-09
Organism	Homo sapiens(human)
Product	SH2 domain-containing protein 4A isoform c
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from BC082982.1, DB183296.1, AK024799.1 and CA418381.1. On May 8, 2018 this sequence version replaced XM_017013729.1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1803611.23330.1, SRR1803611.87235.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1968540, SAMEA1968832 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGCTGAAAC AGATACTGTC GGAGATGTAC ATAGATCCTG ATCTACTGGC AGAGCTCAGC 
GAAGAACAGA AACAGATCCT GTTCTTCAAG ATGAGAGAGG AACAGATCCG ACGATGGAAA 
GAAAGAGAAG CAGCTATGGA AAGAAAGGAG TCCCTGCCAG TGAAACCCAG ACCAAAGAAA 
GAGAATGGCA AATCGGTTCA TTGGAAACTT GGAGCTGATA AGGAAGTCTG GGTATGGGTG 
ATGGGCGAAC ACCATCTAGA TAAACCCTAT GATGTGCTCT GTAATGAAAT TATTGCTGAG 
AGGGCCCGGC TGAAAGCAGA ACAGGAGGCA GAAGAGCCCA GAAAAACTCA CTCTGAAGAA 
TTCACCAATA GCTTGAAAAC AAAATCACAG TACCATGATC TGCAGGCTCC GGATAACCAG 
CAGACTAAAG ACATCTGGAA GAAAGTGGCA GAAAAGGAGG AACTGGAGCA AGGATCGAGG 
CCAGCACCAA CCCTGGAAGA AGAGAAAATC CGAAAGAAAG AATCTATGAA GAAAAAACAA 
GATGAAGAAA TAAATCAAAT AGAAGAAGAG AGAACGAAGC AGATTTGTAA GAGCTGGAAA 
GAAGACTCGG AATGGCAGGC ATCTCTGCGA AAATCCAAAG CAGCTGATGA GAAGAGACGC 
TCCTTGGCTA AACAAGCACG AGAAGACTAC AAGAGGTTAT CCCTCGGGGC CCAGAAAGGA 
AGAGGCGGTG AGAGGCTGCA AAGCCCCTTG CGTGTTCCGC AGAAACCAGA AAGACCTCCC 
CTTCCACCCA AGCCTCAGTT CCTAAACTCA GGGGCATATC CTCAAAAACC TCTTAGAAAT 
CAGGGAGTGG TGAGGACACT GTCCAGCTCT GCCCAAGAGG ACATCATCCG GTGGTTTAAA 
GAGGAGCAGC TACCACTTCG AGCGGGCTAC CAGAAAACCT CAGACACCAT AGCCCCCTGG 
TTCCATGGAA TTCTCACACT CAAGAAAGCA AATGAACTTC TTCTGAGCAC AGGCATGCCC 
GGCAGTTTTC TCATCCGAGT CAGTGAAAGG ATCAAAGGCT ATGCCCTGTC CTATCTGTCG 
GAGGACGGCT GTAAACATTT CCTCATCGAT GCCTCTGCAG ACGCCTACAG CTTCCTGGGC 
GTGGACCAGC TACAGCATGC CACCTTGGCG GATTTGGTGG AATATCACAA GGAGGAACCC 
ATCACTTCCC TGGGGAAGGA GCTCCTTCTC TATCCCTGTG GTCAGCAGGA CCAGCTGCCT 
GACTACCTGG AGCTGTTTGA GTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001350040.1
CDS	309..1592
Translation	MLKQILSEMYIDPDLLAELSEEQKQILFFKMREEQIRRWKEREAAMERKESLPVKPRPKKENGKSVHWKLGADKEVWVWVMGEHHLDKPYDVLCNEIIAERARLKAEQEAEEPRKTHSEEFTNSLKTKSQYHDLQAPDNQQTKDIWKKVAEKEELEQGSRPAPTLEEEKIRKKESMKKKQDEEINQIEEERTKQICKSWKEDSEWQASLRKSKAADEKRRSLAKQAREDYKRLSLGAQKGRGGERLQSPLRVPQKPERPPLPPKPQFLNSGAYPQKPLRNQGVVRTLSSSAQEDIIRWFKEEQLPLRAGYQKTSDTIAPWFHGILTLKKANELLLSTGMPGSFLIRVSERIKGYALSYLSEDGCKHFLIDASADAYSFLGVDQLQHATLADLVEYHKEEPITSLGKELLLYPCGQQDQLPDYLELFE

Target ORF information:

RefSeq Version	NM_001363111.1
Organism	Homo sapiens(human)
Definition	Homo sapiens SH2 domain containing 4A (SH2D4A), transcript variant 5, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001363111.1

ORF Insert Sequence:

ATGCTGAAAC AGATACTGTC GGAGATGTAC ATAGATCCTG ATCTACTGGC AGAGCTCAGC 
GAAGAACAGA AACAGATCCT GTTCTTCAAG ATGAGAGAGG AACAGATCCG ACGATGGAAA 
GAAAGAGAAG CAGCTATGGA AAGAAAGGAG TCCCTGCCAG TGAAACCCAG ACCAAAGAAA 
GAGAATGGCA AATCGGTTCA TTGGAAACTT GGAGCTGATA AGGAAGTCTG GGTATGGGTG 
ATGGGCGAAC ACCATCTAGA TAAACCCTAT GATGTGCTCT GTAATGAAAT TATTGCTGAG 
AGGGCCCGGC TGAAAGCAGA ACAGGAGGCA GAAGAGCCCA GAAAAACTCA CTCTGAAGAA 
TTCACCAATA GCTTGAAAAC AAAATCACAG TACCATGATC TGCAGGCTCC GGATAACCAG 
CAGACTAAAG ACATCTGGAA GAAAGTGGCA GAAAAGGAGG AACTGGAGCA AGGATCGAGG 
CCAGCACCAA CCCTGGAAGA AGAGAAAATC CGAAAGAAAG AATCTATGAA GAAAAAACAA 
GATGAAGAAA TAAATCAAAT AGAAGAAGAG AGAACGAAGC AGATTTGTAA GAGCTGGAAA 
GAAGACTCGG AATGGCAGGC ATCTCTGCGA AAATCCAAAG CAGCTGATGA GAAGAGACGC 
TCCTTGGCTA AACAAGCACG AGAAGACTAC AAGAGGTTAT CCCTCGGGGC CCAGAAAGGA 
AGAGGCGGTG AGAGGCTGCA AAGCCCCTTG CGTGTTCCGC AGAAACCAGA AAGACCTCCC 
CTTCCACCCA AGCCTCAGTT CCTAAACTCA GGGGCATATC CTCAAAAACC TCTTAGAAAT 
CAGGGAGTGG TGAGGACACT GTCCAGCTCT GCCCAAGAGG ACATCATCCG GTGGTTTAAA 
GAGGAGCAGC TACCACTTCG AGCGGGCTAC CAGAAAACCT CAGACACCAT AGCCCCCTGG 
TTCCATGGAA TTCTCACACT CAAGAAAGCA AATGAACTTC TTCTGAGCAC AGGCATGCCC 
GGCAGTTTTC TCATCCGAGT CAGTGAAAGG ATCAAAGGCT ATGCCCTGTC CTATCTGTCG 
GAGGACGGCT GTAAACATTT CCTCATCGAT GCCTCTGCAG ACGCCTACAG CTTCCTGGGC 
GTGGACCAGC TACAGCATGC CACCTTGGCG GATTTGGTGG AATATCACAA GGAGGAACCC 
ATCACTTCCC TGGGGAAGGA GCTCCTTCTC TATCCCTGTG GTCAGCAGGA CCAGCTGCCT 
GACTACCTGG AGCTGTTTGA GTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

SH2D4A ( XM_011544610.1 ) cDNA ORF clone, Homo sapiens(human) -> XP_011542912.1 Homo sapiens SH2 domain containing 4A (SH2D4A), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OHu42126
Clone ID Related Accession (Same CDS sequence)	XM_011544610.1 , XM_017013729.1 , NM_001363110.1 , NM_001363111.1
Accession Version	XM_011544610.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1284bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-06-05
Organism	Homo sapiens(human)
Product	SH2 domain-containing protein 4A isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000008.11) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Homo sapiens Annotation Release 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGCTGAAAC AGATACTGTC GGAGATGTAC ATAGATCCTG ATCTACTGGC AGAGCTCAGC 
GAAGAACAGA AACAGATCCT GTTCTTCAAG ATGAGAGAGG AACAGATCCG ACGATGGAAA 
GAAAGAGAAG CAGCTATGGA AAGAAAGGAG TCCCTGCCAG TGAAACCCAG ACCAAAGAAA 
GAGAATGGCA AATCGGTTCA TTGGAAACTT GGAGCTGATA AGGAAGTCTG GGTATGGGTG 
ATGGGCGAAC ACCATCTAGA TAAACCCTAT GATGTGCTCT GTAATGAAAT TATTGCTGAG 
AGGGCCCGGC TGAAAGCAGA ACAGGAGGCA GAAGAGCCCA GAAAAACTCA CTCTGAAGAA 
TTCACCAATA GCTTGAAAAC AAAATCACAG TACCATGATC TGCAGGCTCC GGATAACCAG 
CAGACTAAAG ACATCTGGAA GAAAGTGGCA GAAAAGGAGG AACTGGAGCA AGGATCGAGG 
CCAGCACCAA CCCTGGAAGA AGAGAAAATC CGAAAGAAAG AATCTATGAA GAAAAAACAA 
GATGAAGAAA TAAATCAAAT AGAAGAAGAG AGAACGAAGC AGATTTGTAA GAGCTGGAAA 
GAAGACTCGG AATGGCAGGC ATCTCTGCGA AAATCCAAAG CAGCTGATGA GAAGAGACGC 
TCCTTGGCTA AACAAGCACG AGAAGACTAC AAGAGGTTAT CCCTCGGGGC CCAGAAAGGA 
AGAGGCGGTG AGAGGCTGCA AAGCCCCTTG CGTGTTCCGC AGAAACCAGA AAGACCTCCC 
CTTCCACCCA AGCCTCAGTT CCTAAACTCA GGGGCATATC CTCAAAAACC TCTTAGAAAT 
CAGGGAGTGG TGAGGACACT GTCCAGCTCT GCCCAAGAGG ACATCATCCG GTGGTTTAAA 
GAGGAGCAGC TACCACTTCG AGCGGGCTAC CAGAAAACCT CAGACACCAT AGCCCCCTGG 
TTCCATGGAA TTCTCACACT CAAGAAAGCA AATGAACTTC TTCTGAGCAC AGGCATGCCC 
GGCAGTTTTC TCATCCGAGT CAGTGAAAGG ATCAAAGGCT ATGCCCTGTC CTATCTGTCG 
GAGGACGGCT GTAAACATTT CCTCATCGAT GCCTCTGCAG ACGCCTACAG CTTCCTGGGC 
GTGGACCAGC TACAGCATGC CACCTTGGCG GATTTGGTGG AATATCACAA GGAGGAACCC 
ATCACTTCCC TGGGGAAGGA GCTCCTTCTC TATCCCTGTG GTCAGCAGGA CCAGCTGCCT 
GACTACCTGG AGCTGTTTGA GTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_011542912.1
CDS	586..1869
Translation	MLKQILSEMYIDPDLLAELSEEQKQILFFKMREEQIRRWKEREAAMERKESLPVKPRPKKENGKSVHWKLGADKEVWVWVMGEHHLDKPYDVLCNEIIAERARLKAEQEAEEPRKTHSEEFTNSLKTKSQYHDLQAPDNQQTKDIWKKVAEKEELEQGSRPAPTLEEEKIRKKESMKKKQDEEINQIEEERTKQICKSWKEDSEWQASLRKSKAADEKRRSLAKQAREDYKRLSLGAQKGRGGERLQSPLRVPQKPERPPLPPKPQFLNSGAYPQKPLRNQGVVRTLSSSAQEDIIRWFKEEQLPLRAGYQKTSDTIAPWFHGILTLKKANELLLSTGMPGSFLIRVSERIKGYALSYLSEDGCKHFLIDASADAYSFLGVDQLQHATLADLVEYHKEEPITSLGKELLLYPCGQQDQLPDYLELFE

Target ORF information:

RefSeq Version	XM_011544610.1
Organism	Homo sapiens(human)
Definition	Homo sapiens SH2 domain containing 4A (SH2D4A), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_011544610.1

ORF Insert Sequence:

ATGCTGAAAC AGATACTGTC GGAGATGTAC ATAGATCCTG ATCTACTGGC AGAGCTCAGC 
GAAGAACAGA AACAGATCCT GTTCTTCAAG ATGAGAGAGG AACAGATCCG ACGATGGAAA 
GAAAGAGAAG CAGCTATGGA AAGAAAGGAG TCCCTGCCAG TGAAACCCAG ACCAAAGAAA 
GAGAATGGCA AATCGGTTCA TTGGAAACTT GGAGCTGATA AGGAAGTCTG GGTATGGGTG 
ATGGGCGAAC ACCATCTAGA TAAACCCTAT GATGTGCTCT GTAATGAAAT TATTGCTGAG 
AGGGCCCGGC TGAAAGCAGA ACAGGAGGCA GAAGAGCCCA GAAAAACTCA CTCTGAAGAA 
TTCACCAATA GCTTGAAAAC AAAATCACAG TACCATGATC TGCAGGCTCC GGATAACCAG 
CAGACTAAAG ACATCTGGAA GAAAGTGGCA GAAAAGGAGG AACTGGAGCA AGGATCGAGG 
CCAGCACCAA CCCTGGAAGA AGAGAAAATC CGAAAGAAAG AATCTATGAA GAAAAAACAA 
GATGAAGAAA TAAATCAAAT AGAAGAAGAG AGAACGAAGC AGATTTGTAA GAGCTGGAAA 
GAAGACTCGG AATGGCAGGC ATCTCTGCGA AAATCCAAAG CAGCTGATGA GAAGAGACGC 
TCCTTGGCTA AACAAGCACG AGAAGACTAC AAGAGGTTAT CCCTCGGGGC CCAGAAAGGA 
AGAGGCGGTG AGAGGCTGCA AAGCCCCTTG CGTGTTCCGC AGAAACCAGA AAGACCTCCC 
CTTCCACCCA AGCCTCAGTT CCTAAACTCA GGGGCATATC CTCAAAAACC TCTTAGAAAT 
CAGGGAGTGG TGAGGACACT GTCCAGCTCT GCCCAAGAGG ACATCATCCG GTGGTTTAAA 
GAGGAGCAGC TACCACTTCG AGCGGGCTAC CAGAAAACCT CAGACACCAT AGCCCCCTGG 
TTCCATGGAA TTCTCACACT CAAGAAAGCA AATGAACTTC TTCTGAGCAC AGGCATGCCC 
GGCAGTTTTC TCATCCGAGT CAGTGAAAGG ATCAAAGGCT ATGCCCTGTC CTATCTGTCG 
GAGGACGGCT GTAAACATTT CCTCATCGAT GCCTCTGCAG ACGCCTACAG CTTCCTGGGC 
GTGGACCAGC TACAGCATGC CACCTTGGCG GATTTGGTGG AATATCACAA GGAGGAACCC 
ATCACTTCCC TGGGGAAGGA GCTCCTTCTC TATCCCTGTG GTCAGCAGGA CCAGCTGCCT 
GACTACCTGG AGCTGTTTGA GTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

SH2D4A ( XM_017013729.1 ) cDNA ORF clone, Homo sapiens(human) -> XP_016869218.1 Homo sapiens SH2 domain containing 4A (SH2D4A), transcript variant X2, mRNA.

Price & Availability↑

CloneID	OHu42126
Clone ID Related Accession (Same CDS sequence)	XM_011544610.1 , XM_017013729.1 , NM_001363110.1 , NM_001363111.1
Accession Version	XM_017013729.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1284bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-06-05
Organism	Homo sapiens(human)
Product	SH2 domain-containing protein 4A isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000008.11) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Homo sapiens Annotation Release 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGCTGAAAC AGATACTGTC GGAGATGTAC ATAGATCCTG ATCTACTGGC AGAGCTCAGC 
GAAGAACAGA AACAGATCCT GTTCTTCAAG ATGAGAGAGG AACAGATCCG ACGATGGAAA 
GAAAGAGAAG CAGCTATGGA AAGAAAGGAG TCCCTGCCAG TGAAACCCAG ACCAAAGAAA 
GAGAATGGCA AATCGGTTCA TTGGAAACTT GGAGCTGATA AGGAAGTCTG GGTATGGGTG 
ATGGGCGAAC ACCATCTAGA TAAACCCTAT GATGTGCTCT GTAATGAAAT TATTGCTGAG 
AGGGCCCGGC TGAAAGCAGA ACAGGAGGCA GAAGAGCCCA GAAAAACTCA CTCTGAAGAA 
TTCACCAATA GCTTGAAAAC AAAATCACAG TACCATGATC TGCAGGCTCC GGATAACCAG 
CAGACTAAAG ACATCTGGAA GAAAGTGGCA GAAAAGGAGG AACTGGAGCA AGGATCGAGG 
CCAGCACCAA CCCTGGAAGA AGAGAAAATC CGAAAGAAAG AATCTATGAA GAAAAAACAA 
GATGAAGAAA TAAATCAAAT AGAAGAAGAG AGAACGAAGC AGATTTGTAA GAGCTGGAAA 
GAAGACTCGG AATGGCAGGC ATCTCTGCGA AAATCCAAAG CAGCTGATGA GAAGAGACGC 
TCCTTGGCTA AACAAGCACG AGAAGACTAC AAGAGGTTAT CCCTCGGGGC CCAGAAAGGA 
AGAGGCGGTG AGAGGCTGCA AAGCCCCTTG CGTGTTCCGC AGAAACCAGA AAGACCTCCC 
CTTCCACCCA AGCCTCAGTT CCTAAACTCA GGGGCATATC CTCAAAAACC TCTTAGAAAT 
CAGGGAGTGG TGAGGACACT GTCCAGCTCT GCCCAAGAGG ACATCATCCG GTGGTTTAAA 
GAGGAGCAGC TACCACTTCG AGCGGGCTAC CAGAAAACCT CAGACACCAT AGCCCCCTGG 
TTCCATGGAA TTCTCACACT CAAGAAAGCA AATGAACTTC TTCTGAGCAC AGGCATGCCC 
GGCAGTTTTC TCATCCGAGT CAGTGAAAGG ATCAAAGGCT ATGCCCTGTC CTATCTGTCG 
GAGGACGGCT GTAAACATTT CCTCATCGAT GCCTCTGCAG ACGCCTACAG CTTCCTGGGC 
GTGGACCAGC TACAGCATGC CACCTTGGCG GATTTGGTGG AATATCACAA GGAGGAACCC 
ATCACTTCCC TGGGGAAGGA GCTCCTTCTC TATCCCTGTG GTCAGCAGGA CCAGCTGCCT 
GACTACCTGG AGCTGTTTGA GTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_016869218.1
CDS	308..1591
Translation	MLKQILSEMYIDPDLLAELSEEQKQILFFKMREEQIRRWKEREAAMERKESLPVKPRPKKENGKSVHWKLGADKEVWVWVMGEHHLDKPYDVLCNEIIAERARLKAEQEAEEPRKTHSEEFTNSLKTKSQYHDLQAPDNQQTKDIWKKVAEKEELEQGSRPAPTLEEEKIRKKESMKKKQDEEINQIEEERTKQICKSWKEDSEWQASLRKSKAADEKRRSLAKQAREDYKRLSLGAQKGRGGERLQSPLRVPQKPERPPLPPKPQFLNSGAYPQKPLRNQGVVRTLSSSAQEDIIRWFKEEQLPLRAGYQKTSDTIAPWFHGILTLKKANELLLSTGMPGSFLIRVSERIKGYALSYLSEDGCKHFLIDASADAYSFLGVDQLQHATLADLVEYHKEEPITSLGKELLLYPCGQQDQLPDYLELFE

Target ORF information:

RefSeq Version	XM_017013729.1
Organism	Homo sapiens(human)
Definition	Homo sapiens SH2 domain containing 4A (SH2D4A), transcript variant X2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_017013729.1

ORF Insert Sequence:

ATGCTGAAAC AGATACTGTC GGAGATGTAC ATAGATCCTG ATCTACTGGC AGAGCTCAGC 
GAAGAACAGA AACAGATCCT GTTCTTCAAG ATGAGAGAGG AACAGATCCG ACGATGGAAA 
GAAAGAGAAG CAGCTATGGA AAGAAAGGAG TCCCTGCCAG TGAAACCCAG ACCAAAGAAA 
GAGAATGGCA AATCGGTTCA TTGGAAACTT GGAGCTGATA AGGAAGTCTG GGTATGGGTG 
ATGGGCGAAC ACCATCTAGA TAAACCCTAT GATGTGCTCT GTAATGAAAT TATTGCTGAG 
AGGGCCCGGC TGAAAGCAGA ACAGGAGGCA GAAGAGCCCA GAAAAACTCA CTCTGAAGAA 
TTCACCAATA GCTTGAAAAC AAAATCACAG TACCATGATC TGCAGGCTCC GGATAACCAG 
CAGACTAAAG ACATCTGGAA GAAAGTGGCA GAAAAGGAGG AACTGGAGCA AGGATCGAGG 
CCAGCACCAA CCCTGGAAGA AGAGAAAATC CGAAAGAAAG AATCTATGAA GAAAAAACAA 
GATGAAGAAA TAAATCAAAT AGAAGAAGAG AGAACGAAGC AGATTTGTAA GAGCTGGAAA 
GAAGACTCGG AATGGCAGGC ATCTCTGCGA AAATCCAAAG CAGCTGATGA GAAGAGACGC 
TCCTTGGCTA AACAAGCACG AGAAGACTAC AAGAGGTTAT CCCTCGGGGC CCAGAAAGGA 
AGAGGCGGTG AGAGGCTGCA AAGCCCCTTG CGTGTTCCGC AGAAACCAGA AAGACCTCCC 
CTTCCACCCA AGCCTCAGTT CCTAAACTCA GGGGCATATC CTCAAAAACC TCTTAGAAAT 
CAGGGAGTGG TGAGGACACT GTCCAGCTCT GCCCAAGAGG ACATCATCCG GTGGTTTAAA 
GAGGAGCAGC TACCACTTCG AGCGGGCTAC CAGAAAACCT CAGACACCAT AGCCCCCTGG 
TTCCATGGAA TTCTCACACT CAAGAAAGCA AATGAACTTC TTCTGAGCAC AGGCATGCCC 
GGCAGTTTTC TCATCCGAGT CAGTGAAAGG ATCAAAGGCT ATGCCCTGTC CTATCTGTCG 
GAGGACGGCT GTAAACATTT CCTCATCGAT GCCTCTGCAG ACGCCTACAG CTTCCTGGGC 
GTGGACCAGC TACAGCATGC CACCTTGGCG GATTTGGTGG AATATCACAA GGAGGAACCC 
ATCACTTCCC TGGGGAAGGA GCTCCTTCTC TATCCCTGTG GTCAGCAGGA CCAGCTGCCT 
GACTACCTGG AGCTGTTTGA GTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Architecture of the human interactome defines protein communities and disease networks.
Nature545(7655)505-509(2017 05)
Huttlin EL,Bruckner RJ,Paulo JA,Cannon JR,Ting L,Baltier K,Colby G,Gebreab F,Gygi MP,Parzen H,Szpyt J,Tam S,Zarraga G,Pontano-Vaites L,Swarup S,White AE,Schweppe DK,Rad R,Erickson BK,Obar RA,Guruharsha KG,Li K,Artavanis-Tsakonas S,Gygi SP,Harper JW

Systematic Analysis of Human Protein Phosphatase Interactions and Dynamics.
Cell systems4(4)430-444.e5(2017 Apr)
Yadav L,Tamene F,G??s H,van Drogen A,Katainen R,Aebersold R,Gstaiger M,Varjosalo M

Chromosome 8p tumor suppressor genes SH2D4A and SORBS3 cooperate to inhibit interleukin-6 signaling in hepatocellular carcinoma.
Hepatology (Baltimore, Md.)64(3)828-42(2016 09)
Ploeger C,Waldburger N,Fraas A,Goeppert B,Pusch S,Breuhahn K,Wang XW,Schirmacher P,Roessler S

An organelle-specific protein landscape identifies novel diseases and molecular mechanisms.
Nature communications711491(2016 May)
Boldt K,van Reeuwijk J,Lu Q,Koutroumpas K,Nguyen TM,Texier Y,van Beersum SE,Horn N,Willer JR,Mans DA,Dougherty G,Lamers IJ,Coene KL,Arts HH,Betts MJ,Beyer T,Bolat E,Gloeckner CJ,Haidari K,Hetterschijt L,Iaconis D,Jenkins D,Klose F,Knapp B,Latour B,Letteboer SJ,Marcelis CL,Mitic D,Morleo M,Oud MM,Riemersma M,Rix S,Terhal PA,Toedt G,van Dam TJ,de Vrieze E,Wissinger Y,Wu KM,Apic G,Beales PL,Blacque OE,Gibson TJ,Huynen MA,Katsanis N,Kremer H,Omran H,van Wijk E,Wolfrum U,Kepes F,Davis EE,Franco B,Giles RH,Ueffing M,Russell RB,Roepman R,

Pooled-matrix protein interaction screens using Barcode Fusion Genetics.
Molecular systems biology12(4)863(2016 Apr)
Yachie N,Petsalaki E,Mellor JC,Weile J,Jacob Y,Verby M,Ozturk SB,Li S,Cote AG,Mosca R,Knapp JJ,Ko M,Yu A,Gebbia M,Sahni N,Yi S,Tyagi T,Sheykhkarimli D,Roth JF,Wong C,Musa L,Snider J,Liu YC,Yu H,Braun P,Stagljar I,Hao T,Calderwood MA,Pelletier L,Aloy P,Hill DE,Vidal M,Roth FP

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SH2D4A cDNA ORF clone, Homo sapiens(human)

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Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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