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ALDH8A1 cDNA ORF clone, Homo sapiens(human)

Summary

Gene Symbol ALDH8A1
Entrez Gene ID 64577
Full Name aldehyde dehydrogenase 8 family member A1
Synonyms ALDH12,DJ352A20.2
General protein information
Preferred Names

aldehyde dehydrogenase 8 family member A1

Names

aldehyde dehydrogenase family 8 member A1
aldehyde dehydrogenase 12
aldehyde dehydrogenase family protein
Gene Type protein-coding
Organism Homo sapiens(human)
Genome

6

6q23.3
Summary This protein belongs to the aldehyde dehydrogenases family of proteins. It plays a role in a pathway of 9-cis-retinoic acid biosynthesis in vivo. This enzyme converts 9-cis-retinal into the retinoid X receptor ligand 9-cis-retinoic acid, and has approximately 40-fold higher activity with 9-cis-retinal than with all-trans-retinal. Therefore, it is the first known aldehyde dehydrogenase to show a preference for 9-cis-retinal relative to all-trans-retinal. Three transcript variants encoding distinct protein isoforms have been identified for this gene. [provided by RefSeq, Jul 2010].
Disorder MIM:

606467


Reference Sequences (RefSeq)

mRNA and Protein(s)

mRNA Protein Name
NM_170771.3 NP_739577.1 2-aminomuconic semialdehyde dehydrogenase isoform 2
NM_022568.4 NP_072090.1 2-aminomuconic semialdehyde dehydrogenase isoform 1
NM_001193480.2 NP_001180409.1 2-aminomuconic semialdehyde dehydrogenase isoform 3
NM_001193480.1 NP_001180409.1 2-aminomuconic semialdehyde dehydrogenase isoform 3
NM_170771.2 NP_739577.1 2-aminomuconic semialdehyde dehydrogenase isoform 2
NM_022568.3 NP_072090.1 aldehyde dehydrogenase family 8 member A1 isoform 1

Pathways from BioSystems


Homologies


Homo sapiens (human) ALDH8A1 NP_072090.1
Pan troglodytes (chimpanzee) ALDH8A1 XP_001170111.2
Canis lupus familiaris (dog) ALDH8A1 XP_533415.2
Bos taurus (cattle) ALDH8A1 NP_001069094.1
Gallus gallus (chicken) ALDH8A1 XP_419732.1
Caenorhabditis elegans (roundworm) alh-10 NP_509203.1
Xenopus tropicalis (tropical clawed frog) aldh8a1 XP_002935852.1
Danio rerio (zebrafish) aldh8a1 NP_001004540.1
LOC712386 XP_001101362.1
Mus musculus (house mouse) Aldh8a1 NP_848828.1
Rattus norvegicus (Norway rat) Aldh8a1 NP_001178017.1

Gene Ontology


Bibliography

Related articles in PubMed

Genetics of coronary artery calcification among African Americans, a meta-analysis.
Wojczynski MK, Li M, Bielak LF, Kerr KF, Reiner AP, Wong ND, Yanek LR, Qu L, White CC, Lange LA, Ferguson JF, He J, Young T, Mosley TH, Smith JA, Kral BG, Guo X, Wong Q, Ganesh SK, Heckbert SR, Griswold ME, O'Leary DH, Budoff M, Carr JJ, Taylor HA Jr, Bluemke DA, Demissie S, Hwang SJ, Paltoo DN, Polak JF, Psaty BM, Becker DM, Province MA, Post WS, O'Donnell CJ, Wilson JG, Harris TB, Kavousi M, Cupples LA, Rotter JI, Fornage M, Becker LC, Peyser PA, Borecki IB, Reilly MP
BMC medical genetics1475(2013 Jul)

Association study between single-nucleotide polymorphisms in 199 drug-related genes and commonly measured quantitative traits of 752 healthy Japanese subjects.
Saito A, Kawamoto M, Kamatani N
Journal of human genetics54(6)317-23(2009 Jun)

Large-scale proteomics and phosphoproteomics of urinary exosomes.
Gonzales PA, Pisitkun T, Hoffert JD, Tchapyjnikov D, Star RA, Kleta R, Wang NS, Knepper MA
Journal of the American Society of Nephrology : JASN20(2)363-79(2009 Feb)

cDNA cloning and expression of a human aldehyde dehydrogenase (ALDH) active with 9-cis-retinal and identification of a rat ortholog, ALDH12.
Lin M, Napoli JL
The Journal of biological chemistry275(51)40106-12(2000 Dec)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Observational study of gene-disease association. (HuGE Navigator)
Title: Association study between single-nucleotide polymorphisms in 199 drug-related genes and commonly measured quantitative traits of 752 healthy Japanese subjects.

The following ALDH8A1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the ALDH8A1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID Accession No. Definition **Vector *Turnaround time Price (USD) Select
OHu18324 NM_022568.4
Latest version!		 Homo sapiens aldehyde dehydrogenase 8 family member A1 (ALDH8A1), transcript variant 1, mRNA. pcDNA3.1+/C-(K)DYK or customized vector
in pcDNA3.1+/C-(K)DYK		 $189.50-$265.30
$379.00
OHu09340 NM_170771.3
Latest version!		 Homo sapiens aldehyde dehydrogenase 8 family member A1 (ALDH8A1), transcript variant 2, mRNA. pcDNA3.1+/C-(K)DYK or customized vector 7-9 $223.30
$319.00
OHu09488 NM_001193480.2
Latest version!		 Homo sapiens aldehyde dehydrogenase 8 family member A1 (ALDH8A1), transcript variant 3, mRNA. pcDNA3.1+/C-(K)DYK or customized vector 7-9 $258.30
$369.00
View Old Accession Versions >>
OHu09488 NM_001193480.1 Homo sapiens aldehyde dehydrogenase 8 family member A1 (ALDH8A1), transcript variant 3, mRNA. pcDNA3.1+/C-(K)DYK or customized vector 7-9 $258.30
$369.00
OHu09340 NM_170771.2 Homo sapiens aldehyde dehydrogenase 8 family member A1 (ALDH8A1), transcript variant 2, mRNA. pcDNA3.1+/C-(K)DYK or customized vector 7-9 $223.30
$319.00
OHu18324 NM_022568.3 Homo sapiens aldehyde dehydrogenase 8 family member A1 (ALDH8A1), transcript variant 1, mRNA. pcDNA3.1+/C-(K)DYK or customized vector
in pcDNA3.1+/C-(K)DYK		 $189.50-$265.30
$379.00
Hide Old Accession Versions >>

ORF Online Only Promotion

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)


CloneID OHu18324
Clone ID Related Accession (Same CDS sequence) NM_022568.4 , NM_022568.3
Accession Version NM_022568.4 Latest version! Documents for ORF clone product in default vector
Sequence Information ORF Nucleotide Sequence (Length: 1464bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ™ Seamless cloning technology
Insert Structure linear
Update Date 2019-08-21
Organism Homo sapiens(human)
Product 2-aminomuconic semialdehyde dehydrogenase isoform 1
Comment Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AF303134.1, BX647324.1 and BF590409.1. This sequence is a reference standard in the RefSeqGene project. On Nov 22, 2018 this sequence version replaced NM_022568.3. Transcript Variant: This variant (1) represents the longer transcript, and encodes the longer protein (isoform 1). ##Evidence-Data-START## Transcript exon combination :: AF303134.1, ERR279862.3397.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2155590 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000265605.7/ ENSP00000265605.2 RefSeq Select criteria :: based on conservation, expression, longest protein ##RefSeq-Attributes-END## COMPLETENESS: full length. 

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
ATGGCTGGAA CAAACGCACT TTTGATGCTG GAAAACTTCA TAGATGGAAA ATTTTTACCT 
TGTAGCTCAT ATATAGATTC TTACGACCCA TCAACAGGGG AAGTGTATTG CAGAGTGCCA 
AATAGTGGAA AAGACGAGAT CGAAGCCGCG GTCAAGGCCG CCAGAGAAGC CTTTCCCAGC 
TGGTCATCCC GCAGCCCCCA GGAGCGCTCA CGGGTCCTGA ACCAGGTGGC GGATTTGCTG 
GAGCAGTCCC TGGAGGAGTT TGCCCAGGCC GAGTCTAAAG ACCAAGGGAA AACCTTAGCA 
CTGGCAAGAA CCATGGACAT TCCCCGGTCT GTGCAGAACT TCAGGTTCTT CGCTTCCTCC 
AGCCTGCACC ACACGTCAGA GTGCACGCAG ATGGACCACC TGGGCTGCAT GCACTACACG 
GTGCGGGCCC CGGTGGGAGT CGCTGGTCTG ATCAGCCCCT GGAATTTGCC ACTCTACTTG 
CTGACCTGGA AGATAGCTCC AGCGATGGCT GCAGGGAACA CTGTGATAGC CAAGCCCAGT 
GAGCTGACTT CAGTGACTGC GTGGATGTTG TGCAAACTCC TGGATAAAGC AGGTGTTCCA 
CCAGGTGTGG TCAATATTGT GTTTGGAACC GGGCCCAGGG TGGGTGAGGC CCTGGTGTCC 
CACCCAGAGG TGCCCCTGAT CTCCTTCACC GGGAGCCAGC CCACCGCTGA GCGGATCACC 
CAGCTGAGCG CTCCCCACTG CAAAAAGCTC TCCCTGGAGC TGGGGGGCAA GAATCCTGCC 
ATCATCTTTG AGGACGCCAA CCTGGATGAG TGCATTCCGG CAACCGTCAG GTCCAGCTTT 
GCCAACCAGG GTGAAATCTG TCTCTGTACC AGCAGGATCT TTGTCCAGAA GAGCATCTAT 
AGTGAATTTT TAAAGAGATT TGTAGAAGCT ACCAGAAAGT GGAAAGTCGG CATTCCCTCT 
GATCCACTGG TGAGCATAGG TGCTCTGATA AGTAAAGCAC ATTTGGAGAA AGTCAGAAGT 
TACGTCAAGA GAGCTCTTGC TGAAGGTGCC CAAATTTGGT GCGGTGAGGG AGTGGATAAG 
TTGAGCCTCC CTGCCAGGAA CCAGGCAGGC TACTTTATGC TTCCCACGGT GATAACAGAC 
ATTAAGGATG AATCCTGCTG CATGACGGAA GAGATATTTG GTCCAGTGAC GTGTGTCGTC 
CCCTTTGATA GTGAAGAGGA GGTGATTGAA AGAGCCAACA ACGTTAAGTA TGGGCTGGCG 
GCTACCGTGT GGTCCAGCAA TGTGGGGCGC GTCCACCGGG TGGCTAAGAA GCTGCAGTCT 
GGCTTGGTCT GGACCAACTG CTGGCTCATC AGGGAGCTGA ACCTTCCTTT CGGGGGGATG 
AAGAGTTCTG GAATAGGTAG AGAGGGAGCC AAGGACTCTT ACGACTTCTT CACTGAGATC 
AAAACCATCA CCGTTAAACA CTGA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq NP_072090.1
CDS49..1512
Translation

Target ORF information:

RefSeq Version NM_022568.4
Organism Homo sapiens(human)
Definition Homo sapiens aldehyde dehydrogenase 8 family member A1 (ALDH8A1), transcript variant 1, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
 NM_022568.4

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
ATGGCTGGAA CAAACGCACT TTTGATGCTG GAAAACTTCA TAGATGGAAA ATTTTTACCT 
TGTAGCTCAT ATATAGATTC TTACGACCCA TCAACAGGGG AAGTGTATTG CAGAGTGCCA 
AATAGTGGAA AAGACGAGAT CGAAGCCGCG GTCAAGGCCG CCAGAGAAGC CTTTCCCAGC 
TGGTCATCCC GCAGCCCCCA GGAGCGCTCA CGGGTCCTGA ACCAGGTGGC GGATTTGCTG 
GAGCAGTCCC TGGAGGAGTT TGCCCAGGCC GAGTCTAAAG ACCAAGGGAA AACCTTAGCA 
CTGGCAAGAA CCATGGACAT TCCCCGGTCT GTGCAGAACT TCAGGTTCTT CGCTTCCTCC 
AGCCTGCACC ACACGTCAGA GTGCACGCAG ATGGACCACC TGGGCTGCAT GCACTACACG 
GTGCGGGCCC CGGTGGGAGT CGCTGGTCTG ATCAGCCCCT GGAATTTGCC ACTCTACTTG 
CTGACCTGGA AGATAGCTCC AGCGATGGCT GCAGGGAACA CTGTGATAGC CAAGCCCAGT 
GAGCTGACTT CAGTGACTGC GTGGATGTTG TGCAAACTCC TGGATAAAGC AGGTGTTCCA 
CCAGGTGTGG TCAATATTGT GTTTGGAACC GGGCCCAGGG TGGGTGAGGC CCTGGTGTCC 
CACCCAGAGG TGCCCCTGAT CTCCTTCACC GGGAGCCAGC CCACCGCTGA GCGGATCACC 
CAGCTGAGCG CTCCCCACTG CAAAAAGCTC TCCCTGGAGC TGGGGGGCAA GAATCCTGCC 
ATCATCTTTG AGGACGCCAA CCTGGATGAG TGCATTCCGG CAACCGTCAG GTCCAGCTTT 
GCCAACCAGG GTGAAATCTG TCTCTGTACC AGCAGGATCT TTGTCCAGAA GAGCATCTAT 
AGTGAATTTT TAAAGAGATT TGTAGAAGCT ACCAGAAAGT GGAAAGTCGG CATTCCCTCT 
GATCCACTGG TGAGCATAGG TGCTCTGATA AGTAAAGCAC ATTTGGAGAA AGTCAGAAGT 
TACGTCAAGA GAGCTCTTGC TGAAGGTGCC CAAATTTGGT GCGGTGAGGG AGTGGATAAG 
TTGAGCCTCC CTGCCAGGAA CCAGGCAGGC TACTTTATGC TTCCCACGGT GATAACAGAC 
ATTAAGGATG AATCCTGCTG CATGACGGAA GAGATATTTG GTCCAGTGAC GTGTGTCGTC 
CCCTTTGATA GTGAAGAGGA GGTGATTGAA AGAGCCAACA ACGTTAAGTA TGGGCTGGCG 
GCTACCGTGT GGTCCAGCAA TGTGGGGCGC GTCCACCGGG TGGCTAAGAA GCTGCAGTCT 
GGCTTGGTCT GGACCAACTG CTGGCTCATC AGGGAGCTGA ACCTTCCTTT CGGGGGGATG 
AAGAGTTCTG GAATAGGTAG AGAGGGAGCC AAGGACTCTT ACGACTTCTT CACTGAGATC 
AAAACCATCA CCGTTAAACA CTGA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OHu18324
Clone ID Related Accession (Same CDS sequence) NM_022568.4 , NM_022568.3
Accession Version NM_022568.3 Documents for ORF clone product in default vector
Sequence Information ORF Nucleotide Sequence (Length: 1464bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ™ Seamless cloning technology
Insert Structure linear
Update Date 2017-10-01
Organism Homo sapiens(human)
Product aldehyde dehydrogenase family 8 member A1 isoform 1
Comment Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from DA635162.1, AF303134.1, BX647324.1 and BF590409.1. This sequence is a reference standard in the RefSeqGene project. On Jul 28, 2010 this sequence version replaced NM_022568.2. Transcript Variant: This variant (1) represents the longer transcript, and encodes the longer protein (isoform 1). ##Evidence-Data-START## Transcript exon combination :: AF303134.1, ERR279862.3397.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2155590 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end. 

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
ATGGCTGGAA CAAACGCACT TTTGATGCTG GAAAACTTCA TAGATGGAAA ATTTTTACCT 
TGTAGCTCAT ATATAGATTC TTACGACCCA TCAACAGGGG AAGTGTATTG CAGAGTGCCA 
AATAGTGGAA AAGACGAGAT CGAAGCCGCG GTCAAGGCCG CCAGAGAAGC CTTTCCCAGC 
TGGTCATCCC GCAGCCCCCA GGAGCGCTCA CGGGTCCTGA ACCAGGTGGC GGATTTGCTG 
GAGCAGTCCC TGGAGGAGTT TGCCCAGGCC GAGTCTAAAG ACCAAGGGAA AACCTTAGCA 
CTGGCAAGAA CCATGGACAT TCCCCGGTCT GTGCAGAACT TCAGGTTCTT CGCTTCCTCC 
AGCCTGCACC ACACGTCAGA GTGCACGCAG ATGGACCACC TGGGCTGCAT GCACTACACG 
GTGCGGGCCC CGGTGGGAGT CGCTGGTCTG ATCAGCCCCT GGAATTTGCC ACTCTACTTG 
CTGACCTGGA AGATAGCTCC AGCGATGGCT GCAGGGAACA CTGTGATAGC CAAGCCCAGT 
GAGCTGACTT CAGTGACTGC GTGGATGTTG TGCAAACTCC TGGATAAAGC AGGTGTTCCA 
CCAGGTGTGG TCAATATTGT GTTTGGAACC GGGCCCAGGG TGGGTGAGGC CCTGGTGTCC 
CACCCAGAGG TGCCCCTGAT CTCCTTCACC GGGAGCCAGC CCACCGCTGA GCGGATCACC 
CAGCTGAGCG CTCCCCACTG CAAAAAGCTC TCCCTGGAGC TGGGGGGCAA GAATCCTGCC 
ATCATCTTTG AGGACGCCAA CCTGGATGAG TGCATTCCGG CAACCGTCAG GTCCAGCTTT 
GCCAACCAGG GTGAAATCTG TCTCTGTACC AGCAGGATCT TTGTCCAGAA GAGCATCTAT 
AGTGAATTTT TAAAGAGATT TGTAGAAGCT ACCAGAAAGT GGAAAGTCGG CATTCCCTCT 
GATCCACTGG TGAGCATAGG TGCTCTGATA AGTAAAGCAC ATTTGGAGAA AGTCAGAAGT 
TACGTCAAGA GAGCTCTTGC TGAAGGTGCC CAAATTTGGT GCGGTGAGGG AGTGGATAAG 
TTGAGCCTCC CTGCCAGGAA CCAGGCAGGC TACTTTATGC TTCCCACGGT GATAACAGAC 
ATTAAGGATG AATCCTGCTG CATGACGGAA GAGATATTTG GTCCAGTGAC GTGTGTCGTC 
CCCTTTGATA GTGAAGAGGA GGTGATTGAA AGAGCCAACA ACGTTAAGTA TGGGCTGGCG 
GCTACCGTGT GGTCCAGCAA TGTGGGGCGC GTCCACCGGG TGGCTAAGAA GCTGCAGTCT 
GGCTTGGTCT GGACCAACTG CTGGCTCATC AGGGAGCTGA ACCTTCCTTT CGGGGGGATG 
AAGAGTTCTG GAATAGGTAG AGAGGGAGCC AAGGACTCTT ACGACTTCTT CACTGAGATC 
AAAACCATCA CCGTTAAACA CTGA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq NP_072090.1
CDS70..1533
Translation

Target ORF information:

RefSeq Version NM_022568.3
Organism Homo sapiens(human)
Definition Homo sapiens aldehyde dehydrogenase 8 family member A1 (ALDH8A1), transcript variant 1, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
 NM_022568.3

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
ATGGCTGGAA CAAACGCACT TTTGATGCTG GAAAACTTCA TAGATGGAAA ATTTTTACCT 
TGTAGCTCAT ATATAGATTC TTACGACCCA TCAACAGGGG AAGTGTATTG CAGAGTGCCA 
AATAGTGGAA AAGACGAGAT CGAAGCCGCG GTCAAGGCCG CCAGAGAAGC CTTTCCCAGC 
TGGTCATCCC GCAGCCCCCA GGAGCGCTCA CGGGTCCTGA ACCAGGTGGC GGATTTGCTG 
GAGCAGTCCC TGGAGGAGTT TGCCCAGGCC GAGTCTAAAG ACCAAGGGAA AACCTTAGCA 
CTGGCAAGAA CCATGGACAT TCCCCGGTCT GTGCAGAACT TCAGGTTCTT CGCTTCCTCC 
AGCCTGCACC ACACGTCAGA GTGCACGCAG ATGGACCACC TGGGCTGCAT GCACTACACG 
GTGCGGGCCC CGGTGGGAGT CGCTGGTCTG ATCAGCCCCT GGAATTTGCC ACTCTACTTG 
CTGACCTGGA AGATAGCTCC AGCGATGGCT GCAGGGAACA CTGTGATAGC CAAGCCCAGT 
GAGCTGACTT CAGTGACTGC GTGGATGTTG TGCAAACTCC TGGATAAAGC AGGTGTTCCA 
CCAGGTGTGG TCAATATTGT GTTTGGAACC GGGCCCAGGG TGGGTGAGGC CCTGGTGTCC 
CACCCAGAGG TGCCCCTGAT CTCCTTCACC GGGAGCCAGC CCACCGCTGA GCGGATCACC 
CAGCTGAGCG CTCCCCACTG CAAAAAGCTC TCCCTGGAGC TGGGGGGCAA GAATCCTGCC 
ATCATCTTTG AGGACGCCAA CCTGGATGAG TGCATTCCGG CAACCGTCAG GTCCAGCTTT 
GCCAACCAGG GTGAAATCTG TCTCTGTACC AGCAGGATCT TTGTCCAGAA GAGCATCTAT 
AGTGAATTTT TAAAGAGATT TGTAGAAGCT ACCAGAAAGT GGAAAGTCGG CATTCCCTCT 
GATCCACTGG TGAGCATAGG TGCTCTGATA AGTAAAGCAC ATTTGGAGAA AGTCAGAAGT 
TACGTCAAGA GAGCTCTTGC TGAAGGTGCC CAAATTTGGT GCGGTGAGGG AGTGGATAAG 
TTGAGCCTCC CTGCCAGGAA CCAGGCAGGC TACTTTATGC TTCCCACGGT GATAACAGAC 
ATTAAGGATG AATCCTGCTG CATGACGGAA GAGATATTTG GTCCAGTGAC GTGTGTCGTC 
CCCTTTGATA GTGAAGAGGA GGTGATTGAA AGAGCCAACA ACGTTAAGTA TGGGCTGGCG 
GCTACCGTGT GGTCCAGCAA TGTGGGGCGC GTCCACCGGG TGGCTAAGAA GCTGCAGTCT 
GGCTTGGTCT GGACCAACTG CTGGCTCATC AGGGAGCTGA ACCTTCCTTT CGGGGGGATG 
AAGAGTTCTG GAATAGGTAG AGAGGGAGCC AAGGACTCTT ACGACTTCTT CACTGAGATC 
AAAACCATCA CCGTTAAACA CTGA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OHu09340
Clone ID Related Accession (Same CDS sequence) NM_170771.3 , NM_170771.2
Accession Version NM_170771.3 Latest version! Documents for ORF clone product in default vector
Sequence Information ORF Nucleotide Sequence (Length: 1302bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ™ Seamless cloning technology
Insert Structure linear
Update Date 2019-08-07
Organism Homo sapiens(human)
Product 2-aminomuconic semialdehyde dehydrogenase isoform 2
Comment Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AK074266.1, AK290784.1, BX647324.1 and BF590409.1. On May 31, 2019 this sequence version replaced NM_170771.2. Transcript Variant: This variant (2) lacks an in-frame segment of the coding region, compared to variant 1. It encodes a shorter protein (isoform 2), that is missing an internal segment compared to isoform 1. ##Evidence-Data-START## Transcript exon combination :: AK074266.1, SRR5189664.87762.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2155590 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end. 

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
ATGGCTGGAA CAAACGCACT TTTGATGCTG GAAAACTTCA TAGATGGAAA ATTTTTACCT 
TGTAGCTCAT ATATAGATTC TTACGACCCA TCAACAGGGG AAGTGTATTG CAGAGTGCCA 
AATAGTGGAA AAGACGAGAT CGAAGCCGCG GTCAAGGCCG CCAGAGAAGC CTTTCCCAGC 
TGGTCATCCC GCAGCCCCCA GGAGCGCTCA CGGGTCCTGA ACCAGGTGGC GGATTTGCTG 
GAGCAGTCCC TGGAGGAGTT TGCCCAGGCC GAGTCTAAAG ACCAAGGGAA AACCTTAGCA 
CTGGCAAGAA CCATGGACAT TCCCCGGTCT GTGCAGAACT TCAGGTTCTT CGCTTCCTCC 
AGCCTGCACC ACACGTCAGA GTGCACGCAG ATGGACCACC TGGGCTGCAT GCACTACACG 
GTGCGGGCCC CGGTGGGAGT CGCTGGTCTG ATCAGCCCCT GGAATTTGCC ACTCTACTTG 
CTGACCTGGA AGATAGCTCC AGCGATGGCT GCAGGGAACA CTGTGATAGC CAAGCCCAGT 
GAGCTGACTT CAGTGACTGC GTGGATGTTG TGCAAACTCC TGGATAAAGC AGGTGTTCCA 
CCAGGTGTGG TCAATATTGT GTTTGGAACC GGGCCCAGGG TGGGTGAGGC CCTGGTGTCC 
CACCCAGAGG TGCCCCTGAT CTCCTTCACC GGGAGCCAGC CCACCGCTGA GCGGATCACC 
CAGCTGAGCG CTCCCCACTG CAAAAAGCTC TCCCTGGAGC TGGGGGGCAA GAATCCTGCC 
ATCATCTTTG AGGACGCCAA CCTGGATGAG TGCATTCCGG CAACCGTCAG GTCCAGCTTT 
GCCAACCAGG TCAGAAGTTA CGTCAAGAGA GCTCTTGCTG AAGGTGCCCA AATTTGGTGC 
GGTGAGGGAG TGGATAAGTT GAGCCTCCCT GCCAGGAACC AGGCAGGCTA CTTTATGCTT 
CCCACGGTGA TAACAGACAT TAAGGATGAA TCCTGCTGCA TGACGGAAGA GATATTTGGT 
CCAGTGACGT GTGTCGTCCC CTTTGATAGT GAAGAGGAGG TGATTGAAAG AGCCAACAAC 
GTTAAGTATG GGCTGGCGGC TACCGTGTGG TCCAGCAATG TGGGGCGCGT CCACCGGGTG 
GCTAAGAAGC TGCAGTCTGG CTTGGTCTGG ACCAACTGCT GGCTCATCAG GGAGCTGAAC 
CTTCCTTTCG GGGGGATGAA GAGTTCTGGA ATAGGTAGAG AGGGAGCCAA GGACTCTTAC 
GACTTCTTCA CTGAGATCAA AACCATCACC GTTAAACACT GA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq NP_739577.1
CDS49..1350
Translation

Target ORF information:

RefSeq Version NM_170771.3
Organism Homo sapiens(human)
Definition Homo sapiens aldehyde dehydrogenase 8 family member A1 (ALDH8A1), transcript variant 2, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
 NM_170771.3

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
ATGGCTGGAA CAAACGCACT TTTGATGCTG GAAAACTTCA TAGATGGAAA ATTTTTACCT 
TGTAGCTCAT ATATAGATTC TTACGACCCA TCAACAGGGG AAGTGTATTG CAGAGTGCCA 
AATAGTGGAA AAGACGAGAT CGAAGCCGCG GTCAAGGCCG CCAGAGAAGC CTTTCCCAGC 
TGGTCATCCC GCAGCCCCCA GGAGCGCTCA CGGGTCCTGA ACCAGGTGGC GGATTTGCTG 
GAGCAGTCCC TGGAGGAGTT TGCCCAGGCC GAGTCTAAAG ACCAAGGGAA AACCTTAGCA 
CTGGCAAGAA CCATGGACAT TCCCCGGTCT GTGCAGAACT TCAGGTTCTT CGCTTCCTCC 
AGCCTGCACC ACACGTCAGA GTGCACGCAG ATGGACCACC TGGGCTGCAT GCACTACACG 
GTGCGGGCCC CGGTGGGAGT CGCTGGTCTG ATCAGCCCCT GGAATTTGCC ACTCTACTTG 
CTGACCTGGA AGATAGCTCC AGCGATGGCT GCAGGGAACA CTGTGATAGC CAAGCCCAGT 
GAGCTGACTT CAGTGACTGC GTGGATGTTG TGCAAACTCC TGGATAAAGC AGGTGTTCCA 
CCAGGTGTGG TCAATATTGT GTTTGGAACC GGGCCCAGGG TGGGTGAGGC CCTGGTGTCC 
CACCCAGAGG TGCCCCTGAT CTCCTTCACC GGGAGCCAGC CCACCGCTGA GCGGATCACC 
CAGCTGAGCG CTCCCCACTG CAAAAAGCTC TCCCTGGAGC TGGGGGGCAA GAATCCTGCC 
ATCATCTTTG AGGACGCCAA CCTGGATGAG TGCATTCCGG CAACCGTCAG GTCCAGCTTT 
GCCAACCAGG TCAGAAGTTA CGTCAAGAGA GCTCTTGCTG AAGGTGCCCA AATTTGGTGC 
GGTGAGGGAG TGGATAAGTT GAGCCTCCCT GCCAGGAACC AGGCAGGCTA CTTTATGCTT 
CCCACGGTGA TAACAGACAT TAAGGATGAA TCCTGCTGCA TGACGGAAGA GATATTTGGT 
CCAGTGACGT GTGTCGTCCC CTTTGATAGT GAAGAGGAGG TGATTGAAAG AGCCAACAAC 
GTTAAGTATG GGCTGGCGGC TACCGTGTGG TCCAGCAATG TGGGGCGCGT CCACCGGGTG 
GCTAAGAAGC TGCAGTCTGG CTTGGTCTGG ACCAACTGCT GGCTCATCAG GGAGCTGAAC 
CTTCCTTTCG GGGGGATGAA GAGTTCTGGA ATAGGTAGAG AGGGAGCCAA GGACTCTTAC 
GACTTCTTCA CTGAGATCAA AACCATCACC GTTAAACACT GA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OHu09340
Clone ID Related Accession (Same CDS sequence) NM_170771.3 , NM_170771.2
Accession Version NM_170771.2 Documents for ORF clone product in default vector
Sequence Information ORF Nucleotide Sequence (Length: 1302bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ™ Seamless cloning technology
Insert Structure linear
Update Date 2019-02-21
Organism Homo sapiens(human)
Product 2-aminomuconic semialdehyde dehydrogenase isoform 2
Comment Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from DA635162.1, AK074266.1, AK290784.1, BX647324.1 and BF590409.1. On Jul 28, 2010 this sequence version replaced NM_170771.1. Transcript Variant: This variant (2) lacks an in-frame segment of the coding region, compared to variant 1. It encodes a shorter protein (isoform 2), that is missing an internal segment compared to isoform 1. ##Evidence-Data-START## Transcript exon combination :: AK074266.1, AK222848.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2155590 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end. 

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
ATGGCTGGAA CAAACGCACT TTTGATGCTG GAAAACTTCA TAGATGGAAA ATTTTTACCT 
TGTAGCTCAT ATATAGATTC TTACGACCCA TCAACAGGGG AAGTGTATTG CAGAGTGCCA 
AATAGTGGAA AAGACGAGAT CGAAGCCGCG GTCAAGGCCG CCAGAGAAGC CTTTCCCAGC 
TGGTCATCCC GCAGCCCCCA GGAGCGCTCA CGGGTCCTGA ACCAGGTGGC GGATTTGCTG 
GAGCAGTCCC TGGAGGAGTT TGCCCAGGCC GAGTCTAAAG ACCAAGGGAA AACCTTAGCA 
CTGGCAAGAA CCATGGACAT TCCCCGGTCT GTGCAGAACT TCAGGTTCTT CGCTTCCTCC 
AGCCTGCACC ACACGTCAGA GTGCACGCAG ATGGACCACC TGGGCTGCAT GCACTACACG 
GTGCGGGCCC CGGTGGGAGT CGCTGGTCTG ATCAGCCCCT GGAATTTGCC ACTCTACTTG 
CTGACCTGGA AGATAGCTCC AGCGATGGCT GCAGGGAACA CTGTGATAGC CAAGCCCAGT 
GAGCTGACTT CAGTGACTGC GTGGATGTTG TGCAAACTCC TGGATAAAGC AGGTGTTCCA 
CCAGGTGTGG TCAATATTGT GTTTGGAACC GGGCCCAGGG TGGGTGAGGC CCTGGTGTCC 
CACCCAGAGG TGCCCCTGAT CTCCTTCACC GGGAGCCAGC CCACCGCTGA GCGGATCACC 
CAGCTGAGCG CTCCCCACTG CAAAAAGCTC TCCCTGGAGC TGGGGGGCAA GAATCCTGCC 
ATCATCTTTG AGGACGCCAA CCTGGATGAG TGCATTCCGG CAACCGTCAG GTCCAGCTTT 
GCCAACCAGG TCAGAAGTTA CGTCAAGAGA GCTCTTGCTG AAGGTGCCCA AATTTGGTGC 
GGTGAGGGAG TGGATAAGTT GAGCCTCCCT GCCAGGAACC AGGCAGGCTA CTTTATGCTT 
CCCACGGTGA TAACAGACAT TAAGGATGAA TCCTGCTGCA TGACGGAAGA GATATTTGGT 
CCAGTGACGT GTGTCGTCCC CTTTGATAGT GAAGAGGAGG TGATTGAAAG AGCCAACAAC 
GTTAAGTATG GGCTGGCGGC TACCGTGTGG TCCAGCAATG TGGGGCGCGT CCACCGGGTG 
GCTAAGAAGC TGCAGTCTGG CTTGGTCTGG ACCAACTGCT GGCTCATCAG GGAGCTGAAC 
CTTCCTTTCG GGGGGATGAA GAGTTCTGGA ATAGGTAGAG AGGGAGCCAA GGACTCTTAC 
GACTTCTTCA CTGAGATCAA AACCATCACC GTTAAACACT GA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq NP_739577.1
CDS70..1371
Translation

Target ORF information:

RefSeq Version NM_170771.2
Organism Homo sapiens(human)
Definition Homo sapiens aldehyde dehydrogenase 8 family member A1 (ALDH8A1), transcript variant 2, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
 NM_170771.2

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
ATGGCTGGAA CAAACGCACT TTTGATGCTG GAAAACTTCA TAGATGGAAA ATTTTTACCT 
TGTAGCTCAT ATATAGATTC TTACGACCCA TCAACAGGGG AAGTGTATTG CAGAGTGCCA 
AATAGTGGAA AAGACGAGAT CGAAGCCGCG GTCAAGGCCG CCAGAGAAGC CTTTCCCAGC 
TGGTCATCCC GCAGCCCCCA GGAGCGCTCA CGGGTCCTGA ACCAGGTGGC GGATTTGCTG 
GAGCAGTCCC TGGAGGAGTT TGCCCAGGCC GAGTCTAAAG ACCAAGGGAA AACCTTAGCA 
CTGGCAAGAA CCATGGACAT TCCCCGGTCT GTGCAGAACT TCAGGTTCTT CGCTTCCTCC 
AGCCTGCACC ACACGTCAGA GTGCACGCAG ATGGACCACC TGGGCTGCAT GCACTACACG 
GTGCGGGCCC CGGTGGGAGT CGCTGGTCTG ATCAGCCCCT GGAATTTGCC ACTCTACTTG 
CTGACCTGGA AGATAGCTCC AGCGATGGCT GCAGGGAACA CTGTGATAGC CAAGCCCAGT 
GAGCTGACTT CAGTGACTGC GTGGATGTTG TGCAAACTCC TGGATAAAGC AGGTGTTCCA 
CCAGGTGTGG TCAATATTGT GTTTGGAACC GGGCCCAGGG TGGGTGAGGC CCTGGTGTCC 
CACCCAGAGG TGCCCCTGAT CTCCTTCACC GGGAGCCAGC CCACCGCTGA GCGGATCACC 
CAGCTGAGCG CTCCCCACTG CAAAAAGCTC TCCCTGGAGC TGGGGGGCAA GAATCCTGCC 
ATCATCTTTG AGGACGCCAA CCTGGATGAG TGCATTCCGG CAACCGTCAG GTCCAGCTTT 
GCCAACCAGG TCAGAAGTTA CGTCAAGAGA GCTCTTGCTG AAGGTGCCCA AATTTGGTGC 
GGTGAGGGAG TGGATAAGTT GAGCCTCCCT GCCAGGAACC AGGCAGGCTA CTTTATGCTT 
CCCACGGTGA TAACAGACAT TAAGGATGAA TCCTGCTGCA TGACGGAAGA GATATTTGGT 
CCAGTGACGT GTGTCGTCCC CTTTGATAGT GAAGAGGAGG TGATTGAAAG AGCCAACAAC 
GTTAAGTATG GGCTGGCGGC TACCGTGTGG TCCAGCAATG TGGGGCGCGT CCACCGGGTG 
GCTAAGAAGC TGCAGTCTGG CTTGGTCTGG ACCAACTGCT GGCTCATCAG GGAGCTGAAC 
CTTCCTTTCG GGGGGATGAA GAGTTCTGGA ATAGGTAGAG AGGGAGCCAA GGACTCTTAC 
GACTTCTTCA CTGAGATCAA AACCATCACC GTTAAACACT GA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OHu09488
Clone ID Related Accession (Same CDS sequence) NM_001193480.2 , NM_001193480.1
Accession Version NM_001193480.2 Latest version! Documents for ORF clone product in default vector
Sequence Information ORF Nucleotide Sequence (Length: 1314bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ™ Seamless cloning technology
Insert Structure linear
Update Date 2019-08-07
Organism Homo sapiens(human)
Product 2-aminomuconic semialdehyde dehydrogenase isoform 3
Comment Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from DA635162.1, AK298325.1, BX647324.1 and BF590409.1. On May 31, 2019 this sequence version replaced NM_001193480.1. Transcript Variant: This variant (3) lacks an alternate, in-frame, coding region segment, compared to variant 1. The resulting protein (isoform 3) is shorter when it is compared to isoform 1. ##Evidence-Data-START## Transcript exon combination :: AK298325.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2155590 [ECO:0000348] ##Evidence-Data-END## 

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
ATGGCTGGAA CAAACGCACT TTTGATGCTG GAAAACTTCA TAGATGGAAA ATTTTTACCT 
TGTAGCTCAT ATATAGATTC TTACGACCCA TCAACAGGGG AAGTGTATTG CAGAGTGCCA 
AATAGTGGAA AAGACGAGAT CGAAGCCGCG GTCAAGGCCG CCAGAGAAGC CTTTCCCAGC 
TGGTCATCCC GCAGCCCCCA GGAGCGCTCA CGGGTCCTGA ACCAGGTGGC GGATTTGCTG 
GAGCAGTCCC TGGAGGAGTT TGCCCAGGCC GAGTCTAAAG ACCAAGGGAA AACCTTAGCA 
CTGGCAAGAA CCATGGACAT TCCCCGGTCT GTGCAGAACT TCAGGTTCTT CGCTTCCTCC 
AGCCTGCACC ACACGTCAGA GTGCACGCAG ATGGACCACC TGGGCTGCAT GCACTACACG 
GTGCGGGCCC CGGTGGGAGT CGGTGTTCCA CCAGGTGTGG TCAATATTGT GTTTGGAACC 
GGGCCCAGGG TGGGTGAGGC CCTGGTGTCC CACCCAGAGG TGCCCCTGAT CTCCTTCACC 
GGGAGCCAGC CCACCGCTGA GCGGATCACC CAGCTGAGCG CTCCCCACTG CAAAAAGCTC 
TCCCTGGAGC TGGGGGGCAA GAATCCTGCC ATCATCTTTG AGGACGCCAA CCTGGATGAG 
TGCATTCCGG CAACCGTCAG GTCCAGCTTT GCCAACCAGG GTGAAATCTG TCTCTGTACC 
AGCAGGATCT TTGTCCAGAA GAGCATCTAT AGTGAATTTT TAAAGAGATT TGTAGAAGCT 
ACCAGAAAGT GGAAAGTCGG CATTCCCTCT GATCCACTGG TGAGCATAGG TGCTCTGATA 
AGTAAAGCAC ATTTGGAGAA AGTCAGAAGT TACGTCAAGA GAGCTCTTGC TGAAGGTGCC 
CAAATTTGGT GCGGTGAGGG AGTGGATAAG TTGAGCCTCC CTGCCAGGAA CCAGGCAGGC 
TACTTTATGC TTCCCACGGT GATAACAGAC ATTAAGGATG AATCCTGCTG CATGACGGAA 
GAGATATTTG GTCCAGTGAC GTGTGTCGTC CCCTTTGATA GTGAAGAGGA GGTGATTGAA 
AGAGCCAACA ACGTTAAGTA TGGGCTGGCG GCTACCGTGT GGTCCAGCAA TGTGGGGCGC 
GTCCACCGGG TGGCTAAGAA GCTGCAGTCT GGCTTGGTCT GGACCAACTG CTGGCTCATC 
AGGGAGCTGA ACCTTCCTTT CGGGGGGATG AAGAGTTCTG GAATAGGTAG AGAGGGAGCC 
AAGGACTCTT ACGACTTCTT CACTGAGATC AAAACCATCA CCGTTAAACA CTGA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq NP_001180409.1
CDS49..1362
Translation

Target ORF information:

RefSeq Version NM_001193480.2
Organism Homo sapiens(human)
Definition Homo sapiens aldehyde dehydrogenase 8 family member A1 (ALDH8A1), transcript variant 3, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
 NM_001193480.2

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
ATGGCTGGAA CAAACGCACT TTTGATGCTG GAAAACTTCA TAGATGGAAA ATTTTTACCT 
TGTAGCTCAT ATATAGATTC TTACGACCCA TCAACAGGGG AAGTGTATTG CAGAGTGCCA 
AATAGTGGAA AAGACGAGAT CGAAGCCGCG GTCAAGGCCG CCAGAGAAGC CTTTCCCAGC 
TGGTCATCCC GCAGCCCCCA GGAGCGCTCA CGGGTCCTGA ACCAGGTGGC GGATTTGCTG 
GAGCAGTCCC TGGAGGAGTT TGCCCAGGCC GAGTCTAAAG ACCAAGGGAA AACCTTAGCA 
CTGGCAAGAA CCATGGACAT TCCCCGGTCT GTGCAGAACT TCAGGTTCTT CGCTTCCTCC 
AGCCTGCACC ACACGTCAGA GTGCACGCAG ATGGACCACC TGGGCTGCAT GCACTACACG 
GTGCGGGCCC CGGTGGGAGT CGGTGTTCCA CCAGGTGTGG TCAATATTGT GTTTGGAACC 
GGGCCCAGGG TGGGTGAGGC CCTGGTGTCC CACCCAGAGG TGCCCCTGAT CTCCTTCACC 
GGGAGCCAGC CCACCGCTGA GCGGATCACC CAGCTGAGCG CTCCCCACTG CAAAAAGCTC 
TCCCTGGAGC TGGGGGGCAA GAATCCTGCC ATCATCTTTG AGGACGCCAA CCTGGATGAG 
TGCATTCCGG CAACCGTCAG GTCCAGCTTT GCCAACCAGG GTGAAATCTG TCTCTGTACC 
AGCAGGATCT TTGTCCAGAA GAGCATCTAT AGTGAATTTT TAAAGAGATT TGTAGAAGCT 
ACCAGAAAGT GGAAAGTCGG CATTCCCTCT GATCCACTGG TGAGCATAGG TGCTCTGATA 
AGTAAAGCAC ATTTGGAGAA AGTCAGAAGT TACGTCAAGA GAGCTCTTGC TGAAGGTGCC 
CAAATTTGGT GCGGTGAGGG AGTGGATAAG TTGAGCCTCC CTGCCAGGAA CCAGGCAGGC 
TACTTTATGC TTCCCACGGT GATAACAGAC ATTAAGGATG AATCCTGCTG CATGACGGAA 
GAGATATTTG GTCCAGTGAC GTGTGTCGTC CCCTTTGATA GTGAAGAGGA GGTGATTGAA 
AGAGCCAACA ACGTTAAGTA TGGGCTGGCG GCTACCGTGT GGTCCAGCAA TGTGGGGCGC 
GTCCACCGGG TGGCTAAGAA GCTGCAGTCT GGCTTGGTCT GGACCAACTG CTGGCTCATC 
AGGGAGCTGA ACCTTCCTTT CGGGGGGATG AAGAGTTCTG GAATAGGTAG AGAGGGAGCC 
AAGGACTCTT ACGACTTCTT CACTGAGATC AAAACCATCA CCGTTAAACA CTGA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OHu09488
Clone ID Related Accession (Same CDS sequence) NM_001193480.2 , NM_001193480.1
Accession Version NM_001193480.1 Documents for ORF clone product in default vector
Sequence Information ORF Nucleotide Sequence (Length: 1314bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ™ Seamless cloning technology
Insert Structure linear
Update Date 2019-02-21
Organism Homo sapiens(human)
Product 2-aminomuconic semialdehyde dehydrogenase isoform 3
Comment Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from DA635162.1, AK298325.1, BX647324.1 and BF590409.1. Transcript Variant: This variant (3) lacks an alternate, in-frame, coding region segment, compared to variant 1. The resulting protein (isoform 3) is shorter when it is compared to isoform 1. ##Evidence-Data-START## Transcript exon combination :: AK298325.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2155590 [ECO:0000348] ##Evidence-Data-END## 

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
ATGGCTGGAA CAAACGCACT TTTGATGCTG GAAAACTTCA TAGATGGAAA ATTTTTACCT 
TGTAGCTCAT ATATAGATTC TTACGACCCA TCAACAGGGG AAGTGTATTG CAGAGTGCCA 
AATAGTGGAA AAGACGAGAT CGAAGCCGCG GTCAAGGCCG CCAGAGAAGC CTTTCCCAGC 
TGGTCATCCC GCAGCCCCCA GGAGCGCTCA CGGGTCCTGA ACCAGGTGGC GGATTTGCTG 
GAGCAGTCCC TGGAGGAGTT TGCCCAGGCC GAGTCTAAAG ACCAAGGGAA AACCTTAGCA 
CTGGCAAGAA CCATGGACAT TCCCCGGTCT GTGCAGAACT TCAGGTTCTT CGCTTCCTCC 
AGCCTGCACC ACACGTCAGA GTGCACGCAG ATGGACCACC TGGGCTGCAT GCACTACACG 
GTGCGGGCCC CGGTGGGAGT CGGTGTTCCA CCAGGTGTGG TCAATATTGT GTTTGGAACC 
GGGCCCAGGG TGGGTGAGGC CCTGGTGTCC CACCCAGAGG TGCCCCTGAT CTCCTTCACC 
GGGAGCCAGC CCACCGCTGA GCGGATCACC CAGCTGAGCG CTCCCCACTG CAAAAAGCTC 
TCCCTGGAGC TGGGGGGCAA GAATCCTGCC ATCATCTTTG AGGACGCCAA CCTGGATGAG 
TGCATTCCGG CAACCGTCAG GTCCAGCTTT GCCAACCAGG GTGAAATCTG TCTCTGTACC 
AGCAGGATCT TTGTCCAGAA GAGCATCTAT AGTGAATTTT TAAAGAGATT TGTAGAAGCT 
ACCAGAAAGT GGAAAGTCGG CATTCCCTCT GATCCACTGG TGAGCATAGG TGCTCTGATA 
AGTAAAGCAC ATTTGGAGAA AGTCAGAAGT TACGTCAAGA GAGCTCTTGC TGAAGGTGCC 
CAAATTTGGT GCGGTGAGGG AGTGGATAAG TTGAGCCTCC CTGCCAGGAA CCAGGCAGGC 
TACTTTATGC TTCCCACGGT GATAACAGAC ATTAAGGATG AATCCTGCTG CATGACGGAA 
GAGATATTTG GTCCAGTGAC GTGTGTCGTC CCCTTTGATA GTGAAGAGGA GGTGATTGAA 
AGAGCCAACA ACGTTAAGTA TGGGCTGGCG GCTACCGTGT GGTCCAGCAA TGTGGGGCGC 
GTCCACCGGG TGGCTAAGAA GCTGCAGTCT GGCTTGGTCT GGACCAACTG CTGGCTCATC 
AGGGAGCTGA ACCTTCCTTT CGGGGGGATG AAGAGTTCTG GAATAGGTAG AGAGGGAGCC 
AAGGACTCTT ACGACTTCTT CACTGAGATC AAAACCATCA CCGTTAAACA CTGA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq NP_001180409.1
CDS70..1383
Translation

Target ORF information:

RefSeq Version NM_001193480.1
Organism Homo sapiens(human)
Definition Homo sapiens aldehyde dehydrogenase 8 family member A1 (ALDH8A1), transcript variant 3, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
 NM_001193480.1

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
ATGGCTGGAA CAAACGCACT TTTGATGCTG GAAAACTTCA TAGATGGAAA ATTTTTACCT 
TGTAGCTCAT ATATAGATTC TTACGACCCA TCAACAGGGG AAGTGTATTG CAGAGTGCCA 
AATAGTGGAA AAGACGAGAT CGAAGCCGCG GTCAAGGCCG CCAGAGAAGC CTTTCCCAGC 
TGGTCATCCC GCAGCCCCCA GGAGCGCTCA CGGGTCCTGA ACCAGGTGGC GGATTTGCTG 
GAGCAGTCCC TGGAGGAGTT TGCCCAGGCC GAGTCTAAAG ACCAAGGGAA AACCTTAGCA 
CTGGCAAGAA CCATGGACAT TCCCCGGTCT GTGCAGAACT TCAGGTTCTT CGCTTCCTCC 
AGCCTGCACC ACACGTCAGA GTGCACGCAG ATGGACCACC TGGGCTGCAT GCACTACACG 
GTGCGGGCCC CGGTGGGAGT CGGTGTTCCA CCAGGTGTGG TCAATATTGT GTTTGGAACC 
GGGCCCAGGG TGGGTGAGGC CCTGGTGTCC CACCCAGAGG TGCCCCTGAT CTCCTTCACC 
GGGAGCCAGC CCACCGCTGA GCGGATCACC CAGCTGAGCG CTCCCCACTG CAAAAAGCTC 
TCCCTGGAGC TGGGGGGCAA GAATCCTGCC ATCATCTTTG AGGACGCCAA CCTGGATGAG 
TGCATTCCGG CAACCGTCAG GTCCAGCTTT GCCAACCAGG GTGAAATCTG TCTCTGTACC 
AGCAGGATCT TTGTCCAGAA GAGCATCTAT AGTGAATTTT TAAAGAGATT TGTAGAAGCT 
ACCAGAAAGT GGAAAGTCGG CATTCCCTCT GATCCACTGG TGAGCATAGG TGCTCTGATA 
AGTAAAGCAC ATTTGGAGAA AGTCAGAAGT TACGTCAAGA GAGCTCTTGC TGAAGGTGCC 
CAAATTTGGT GCGGTGAGGG AGTGGATAAG TTGAGCCTCC CTGCCAGGAA CCAGGCAGGC 
TACTTTATGC TTCCCACGGT GATAACAGAC ATTAAGGATG AATCCTGCTG CATGACGGAA 
GAGATATTTG GTCCAGTGAC GTGTGTCGTC CCCTTTGATA GTGAAGAGGA GGTGATTGAA 
AGAGCCAACA ACGTTAAGTA TGGGCTGGCG GCTACCGTGT GGTCCAGCAA TGTGGGGCGC 
GTCCACCGGG TGGCTAAGAA GCTGCAGTCT GGCTTGGTCT GGACCAACTG CTGGCTCATC 
AGGGAGCTGA ACCTTCCTTT CGGGGGGATG AAGAGTTCTG GAATAGGTAG AGAGGGAGCC 
AAGGACTCTT ACGACTTCTT CACTGAGATC AAAACCATCA CCGTTAAACA CTGA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

PubMed

book

Genetics of coronary artery calcification among African Americans, a meta-analysis.
BMC medical genetics1475(2013 Jul)
Wojczynski MK,Li M,Bielak LF,Kerr KF,Reiner AP,Wong ND,Yanek LR,Qu L,White CC,Lange LA,Ferguson JF,He J,Young T,Mosley TH,Smith JA,Kral BG,Guo X,Wong Q,Ganesh SK,Heckbert SR,Griswold ME,O'Leary DH,Budoff M,Carr JJ,Taylor HA Jr,Bluemke DA,Demissie S,Hwang SJ,Paltoo DN,Polak JF,Psaty BM,Becker DM,Province MA,Post WS,O'Donnell CJ,Wilson JG,Harris TB,Kavousi M,Cupples LA,Rotter JI,Fornage M,Becker LC,Peyser PA,Borecki IB,Reilly MP


book

Association study between single-nucleotide polymorphisms in 199 drug-related genes and commonly measured quantitative traits of 752 healthy Japanese subjects.
Journal of human genetics54(6)317-23(2009 Jun)
Saito A,Kawamoto M,Kamatani N


book

Large-scale proteomics and phosphoproteomics of urinary exosomes.
Journal of the American Society of Nephrology : JASN20(2)363-79(2009 Feb)
Gonzales PA,Pisitkun T,Hoffert JD,Tchapyjnikov D,Star RA,Kleta R,Wang NS,Knepper MA


book

cDNA cloning and expression of a human aldehyde dehydrogenase (ALDH) active with 9-cis-retinal and identification of a rat ortholog, ALDH12.
The Journal of biological chemistry275(51)40106-12(2000 Dec)
Lin M,Napoli JL