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BMPR1B cDNA ORF clone, Homo sapiens(Human)

Gene Symbol BMPR1B
Entrez Gene ID 658
Full Name bone morphogenetic protein receptor type 1B
Synonyms ALK-6,ALK6,AMDD,BDA1D,BDA2,CDw293
General protein information
Preferred Names

bone morphogenetic protein receptor type 1B

Names

bone morphogenetic protein receptor type-1B
BMP type-1B receptor
BMPR-1B
activin receptor-like kinase 6
bone morphogenetic protein receptor, type IB
serine/threonine receptor kinase

Gene Type protein-coding
Organism Homo sapiens(Human)
Genome

4

4q22.3

Summary This gene encodes a member of the bone morphogenetic protein (BMP) receptor family of transmembrane serine/threonine kinases. The ligands of this receptor are BMPs, which are members of the TGF-beta superfamily. BMPs are involved in endochondral bone formation and embryogenesis. These proteins transduce their signals through the formation of heteromeric complexes of 2 different types of serine (threonine) kinase receptors: type I receptors of about 50-55 kD and type II receptors of about 70-80 kD. Type II receptors bind ligands in the absence of type I receptors, but they require their respective type I receptors for signaling, whereas type I receptors require their respective type II receptors for ligand binding. Mutations in this gene have been associated with primary pulmonary hypertension. Several transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Feb 2012].
Disorder MIM:

603248

Disorder Html: Brachydactyly, type A2, 112600 (3); Chrondrodysplasia, acromesomelic,

mRNA and Protein(s)

mRNA Protein Name
XM_011532201.2 XP_011530503.1 bone morphogenetic protein receptor type-1B isoform X1
NM_001256794.1 NP_001243723.1 bone morphogenetic protein receptor type-1B isoform b precursor
XM_011532201.1 XP_011530503.1 bone morphogenetic protein receptor type-1B isoform X1
XM_017008558.1 XP_016864047.1 bone morphogenetic protein receptor type-1B isoform X1
XM_017008559.1 XP_016864048.1 bone morphogenetic protein receptor type-1B isoform X1
XM_017008560.1 XP_016864049.1 bone morphogenetic protein receptor type-1B isoform X1
XM_017008561.1 XP_016864050.1 bone morphogenetic protein receptor type-1B isoform X1
NM_001203.2 NP_001194.1 bone morphogenetic protein receptor type-1B isoform b precursor
XM_011532202.1 XP_011530504.1 bone morphogenetic protein receptor type-1B isoform X1
NM_001256793.1 NP_001243722.1 bone morphogenetic protein receptor type-1B isoform a precursor
NM_001256792.1 NP_001243721.1 bone morphogenetic protein receptor type-1B isoform b precursor



Canis lupus familiaris (dog) BMPR1B NP_001138623.1
Caenorhabditis elegans (roundworm) sma-6 NP_495271.1
Pan troglodytes (chimpanzee) BMPR1B XP_517599.3
Bos taurus (cattle) BMPR1B NP_001098798.1
Mus musculus (house mouse) Bmpr1b NP_031586.1
Danio rerio (zebrafish) bmpr1ba NP_571532.1
Xenopus tropicalis (tropical clawed frog) bmpr1b NP_001072633.1
Macaca mulatta (rhesus monkey) BMPR1B XP_001103786.2
Homo sapiens (human) BMPR1B NP_001243722.1
Drosophila melanogaster (fruit fly) tkv NP_787990.1
Anopheles gambiae (African malaria mosquito) AgaP_AGAP009329 XP_309997.3
Gallus gallus (chicken) BMPR1B NP_990463.1


Related articles in PubMed

Long-Range Communication Network in the Type 1B Bone Morphogenetic Protein Receptor.
Evangelista W, Yeh LC, Gmyrek A, Lee JC, Lee JC
Biochemistry54(48)7079-88(2015 Dec)

Two novel disease-causing variants in BMPR1B are associated with brachydactyly type A1.
Racacho L, Byrnes AM, MacDonald H, Dranse HJ, Nikkel SM, Allanson J, Rosser E, Underhill TM, Bulman DE
European journal of human genetics : EJHG23(12)1640-5(2015 Dec)

Novel mutation in the BMPR1B gene (R486L) in a Polish family and further delineation of the phenotypic features of BMPR1B-related brachydactyly.
Badura-Stronka M, Mróz D, Beighton P, Łukawiecki S, Wicher K, Latos-Bieleńska A, Kozłowski K
Birth defects research. Part A, Clinical and molecular teratology103(6)567-72(2015 Jun)

A hypomorphic BMPR1B mutation causes du Pan acromesomelic dysplasia.
Stange K, Désir J, Kakar N, Mueller TD, Budde BS, Gordon CT, Horn D, Seemann P, Borck G
Orphanet journal of rare diseases1084(2015 Jun)

Disequilibrium of BMP2 levels in the breast stem cell niche launches epithelial transformation by overamplifying BMPR1B cell response.
Chapellier M, Bachelard-Cascales E, Schmidt X, Clément F, Treilleux I, Delay E, Jammot A, Ménétrier-Caux C, Pochon G, Besançon R, Voeltzel T, Caron de Fromentel C, Caux C, Blay JY, Iggo R, Maguer-Satta V
Stem cell reports4(2)239-54(2015 Feb)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

BMPR1A and the ubiquitous isoform of BMPR1B differed in mode of translocation into the endoplasmic reticulum; and (ii) BMPR1A was N-glycosylated while BMPR1B was not, resulting in greater efficiency of processing and plasma membrane expression of BMPR1A.
Title: Differential molecular regulation of processing and membrane expression of Type-I BMP receptors: implications for signaling.

Mutations in three genes (GDF5, NPR2, BMPR1B) have been reported to cause different forms of acromesomelic dysplasia
Title: Genetics of human isolated acromesomelic dysplasia.

Results show an association between age-induced depletion of the ovarian reserve and BMPR1B receptor density and suggest that the dysregulation of BMP receptor signalling may inhibit the normal steroidogenic differentiation required for maturation in older patients.
Title: Dysregulation of granulosal bone morphogenetic protein receptor 1B density is associated with reduced ovarian reserve and the age-related decline in human fertility.

Data show that protein kinase LKB1 physically interacts with BMP type I receptors and requires Smad7 protein to promote downregulation of the receptor.
Title: The protein kinase LKB1 negatively regulates bone morphogenetic protein receptor signaling.

Low expression of BMPRIB is associated with breast cancer.
Title: Low expression of BMPRIB indicates poor prognosis of breast cancer and is insensitive to taxane-anthracycline chemotherapy.

The following BMPR1B gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the BMPR1B cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

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***CloneID RefSeq Accession Definition **Vector *Turnaround time Price (USD) Select
OHu11503
NM_001203.2
Latest version!
Homo sapiens bone morphogenetic protein receptor type 1B (BMPR1B), transcript variant 2, mRNA. pcDNA3.1+/C-(K)DYK or customized vector
in pcDNA3.1+/C-(K)DYK
$189.50-$265.30
$379.00
OHu11503
NM_001256794.1
Latest version!
Homo sapiens bone morphogenetic protein receptor type 1B (BMPR1B), transcript variant 4, mRNA. pcDNA3.1+/C-(K)DYK or customized vector
in pcDNA3.1+/C-(K)DYK
$189.50-$265.30
$379.00
OHu11503
NM_001256792.1
Latest version!
Homo sapiens bone morphogenetic protein receptor type 1B (BMPR1B), transcript variant 3, mRNA. pcDNA3.1+/C-(K)DYK or customized vector
in pcDNA3.1+/C-(K)DYK
$189.50-$265.30
$379.00
OHu12264
NM_001256793.1
Latest version!
Homo sapiens bone morphogenetic protein receptor type 1B (BMPR1B), transcript variant 1, mRNA. pcDNA3.1+/C-(K)DYK or customized vector
in pcDNA3.1+/C-(K)DYK
$219.50-$307.30
$439.00
OHu11503
XM_017008559.1
Latest version!
Homo sapiens bone morphogenetic protein receptor type 1B (BMPR1B), transcript variant X2, mRNA. pcDNA3.1+/C-(K)DYK or customized vector
in pcDNA3.1+/C-(K)DYK
$189.50-$265.30
$379.00
OHu11503
XM_011532201.2
Latest version!
Homo sapiens bone morphogenetic protein receptor type 1B (BMPR1B), transcript variant X5, mRNA. pcDNA3.1+/C-(K)DYK or customized vector
in pcDNA3.1+/C-(K)DYK
$189.50-$265.30
$379.00
OHu11503
XM_017008560.1
Latest version!
Homo sapiens bone morphogenetic protein receptor type 1B (BMPR1B), transcript variant X3, mRNA. pcDNA3.1+/C-(K)DYK or customized vector
in pcDNA3.1+/C-(K)DYK
$189.50-$265.30
$379.00
OHu11503
XM_011532202.1
Latest version!
Homo sapiens bone morphogenetic protein receptor, type IB (BMPR1B), transcript variant X2, mRNA. pcDNA3.1+/C-(K)DYK or customized vector
in pcDNA3.1+/C-(K)DYK
$189.50-$265.30
$379.00
OHu11503
XM_017008558.1
Latest version!
Homo sapiens bone morphogenetic protein receptor type 1B (BMPR1B), transcript variant X1, mRNA. pcDNA3.1+/C-(K)DYK or customized vector
in pcDNA3.1+/C-(K)DYK
$189.50-$265.30
$379.00
OHu11503
XM_017008561.1
Latest version!
Homo sapiens bone morphogenetic protein receptor type 1B (BMPR1B), transcript variant X4, mRNA. pcDNA3.1+/C-(K)DYK or customized vector
in pcDNA3.1+/C-(K)DYK
$189.50-$265.30
$379.00
View Old Accession Versions >>
OHu11503
XM_011532201.1 Homo sapiens bone morphogenetic protein receptor, type IB (BMPR1B), transcript variant X1, mRNA. pcDNA3.1+/C-(K)DYK or customized vector
in pcDNA3.1+/C-(K)DYK
$189.50-$265.30
$379.00
Hide Old Accession Versions >>

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***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.


CloneID OHu11503
Clone ID Related Accession (Same CDS sequence) XM_011532201.2 , NM_001256794.1 , XM_011532201.1 , XM_017008558.1 , XM_017008559.1 , XM_017008560.1 , XM_017008561.1 , NM_001203.2 , XM_011532202.1 , NM_001256792.1
Accession Version NM_001256794.1 Latest version! Documents for ORF clone product in dufault vector
Sequence Information ORF Nucleotide Sequence (Length: 1509bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags COA
ORF Insert Method CloneEZ® Seamless cloning technology
Insert Structure linear
Update Date 2016-10-07
Organism Homo sapiens(Human)
Product bone morphogenetic protein receptor type-1B isoform b precursor
Comment REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AK293008.1, AK299930.1 and AC105395.1. Transcript Variant: This variant (4) differs in the 5' UTR and coding sequence compared to variant 1. The resulting isoform (b) is shorter at the N-terminus compared to isoform a. Variants 2, 3, and 4 all encode isoform b. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AK293008.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2145245, SAMEA2145743 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
1501
ATGCTTTTGC GAAGTGCAGG AAAATTAAAT GTGGGCACCA AGAAAGAGGA TGGTGAGAGT 
ACAGCCCCCA CCCCCCGTCC AAAGGTCTTG CGTTGTAAAT GCCACCACCA TTGTCCAGAA
GACTCAGTCA ACAATATTTG CAGCACAGAC GGATATTGTT TCACGATGAT AGAAGAGGAT
GACTCTGGGT TGCCTGTGGT CACTTCTGGT TGCCTAGGAC TAGAAGGCTC AGATTTTCAG
TGTCGGGACA CTCCCATTCC TCATCAAAGA AGATCAATTG AATGCTGCAC AGAAAGGAAC
GAATGTAATA AAGACCTACA CCCTACACTG CCTCCATTGA AAAACAGAGA TTTTGTTGAT
GGACCTATAC ACCACAGGGC TTTACTTATA TCTGTGACTG TCTGTAGTTT GCTCTTGGTC
CTTATCATAT TATTTTGTTA CTTCCGGTAT AAAAGACAAG AAACCAGACC TCGATACAGC
ATTGGGTTAG AACAGGATGA AACTTACATT CCTCCTGGAG AATCCCTGAG AGACTTAATT
GAGCAGTCTC AGAGCTCAGG AAGTGGATCA GGCCTCCCTC TGCTGGTCCA AAGGACTATA
GCTAAGCAGA TTCAGATGGT GAAACAGATT GGAAAAGGTC GCTATGGGGA AGTTTGGATG
GGAAAGTGGC GTGGCGAAAA GGTAGCTGTG AAAGTGTTCT TCACCACAGA GGAAGCCAGC
TGGTTCAGAG AGACAGAAAT ATATCAGACA GTGTTGATGA GGCATGAAAA CATTTTGGGT
TTCATTGCTG CAGATATCAA AGGGACAGGG TCCTGGACCC AGTTGTACCT AATCACAGAC
TATCATGAAA ATGGTTCCCT TTATGATTAT CTGAAGTCCA CCACCCTAGA CGCTAAATCA
ATGCTGAAGT TAGCCTACTC TTCTGTCAGT GGCTTATGTC ATTTACACAC AGAAATCTTT
AGTACTCAAG GCAAACCAGC AATTGCCCAT CGAGATCTGA AAAGTAAAAA CATTCTGGTG
AAGAAAAATG GAACTTGCTG TATTGCTGAC CTGGGCCTGG CTGTTAAATT TATTAGTGAT
ACAAATGAAG TTGACATACC ACCTAACACT CGAGTTGGCA CCAAACGCTA TATGCCTCCA
GAAGTGTTGG ACGAGAGCTT GAACAGAAAT CACTTCCAGT CTTACATCAT GGCTGACATG
TATAGTTTTG GCCTCATCCT TTGGGAGGTT GCTAGGAGAT GTGTATCAGG AGGTATAGTG
GAAGAATACC AGCTTCCTTA TCATGACCTA GTGCCCAGTG ACCCCTCTTA TGAGGACATG
AGGGAGATTG TGTGCATCAA GAAGTTACGC CCCTCATTCC CAAACCGGTG GAGCAGTGAT
GAGTGTCTAA GGCAGATGGG AAAACTCATG ACAGAATGCT GGGCTCACAA TCCTGCATCA
AGGCTGACAG CCCTGCGGGT TAAGAAAACA CTTGCCAAAA TGTCAGAGTC CCAGGACATT
AAACTCTGA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq NP_001243723.1
CDS155..1663
Misc Feature(1)95..97
Misc Feature(2)242..484
Misc Feature(3)533..598
Misc Feature(4)746..1660
Misc Feature(5)767..1621
Misc Feature(6)order(782..796,806..808,839..841,845..847,929..931,989..1000,1010..1012,1016..1018,1148..1150,1154..1156,1160..1165,1169..1171,1202..1204,1211..1213,1271..1282)
Misc Feature(7)order(782..802,806..808,839..841,845..847,989..994,998..1000,1010..1012,1160..1165,1169..1171,1202..1204)
Misc Feature(8)order(794..796,1010..1012,1016..1018,1148..1150,1154..1156,1160..1162,1211..1213,1271..1282)
Misc Feature(9)order(875..880,887..892,899..901,944..946,950..952)
Misc Feature(10)1199..1282
Exon (1)1..137
Exon (2)138..297
Exon (3)298..400
Exon (4)401..503
Exon (5)504..600
Exon (6)601..739
Exon (7)740..932
Exon (8)933..1230
Exon (9)1231..1406
Exon (10)1407..1537
Exon (11)1538..5440
Translation

Target ORF information:

RefSeq Version NM_001256794.1
Organism Homo sapiens(Human)
Definition Homo sapiens bone morphogenetic protein receptor type 1B (BMPR1B), transcript variant 4, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
NM_001256794.1

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
1501
ATGCTTTTGC GAAGTGCAGG AAAATTAAAT GTGGGCACCA AGAAAGAGGA TGGTGAGAGT 
ACAGCCCCCA CCCCCCGTCC AAAGGTCTTG CGTTGTAAAT GCCACCACCA TTGTCCAGAA
GACTCAGTCA ACAATATTTG CAGCACAGAC GGATATTGTT TCACGATGAT AGAAGAGGAT
GACTCTGGGT TGCCTGTGGT CACTTCTGGT TGCCTAGGAC TAGAAGGCTC AGATTTTCAG
TGTCGGGACA CTCCCATTCC TCATCAAAGA AGATCAATTG AATGCTGCAC AGAAAGGAAC
GAATGTAATA AAGACCTACA CCCTACACTG CCTCCATTGA AAAACAGAGA TTTTGTTGAT
GGACCTATAC ACCACAGGGC TTTACTTATA TCTGTGACTG TCTGTAGTTT GCTCTTGGTC
CTTATCATAT TATTTTGTTA CTTCCGGTAT AAAAGACAAG AAACCAGACC TCGATACAGC
ATTGGGTTAG AACAGGATGA AACTTACATT CCTCCTGGAG AATCCCTGAG AGACTTAATT
GAGCAGTCTC AGAGCTCAGG AAGTGGATCA GGCCTCCCTC TGCTGGTCCA AAGGACTATA
GCTAAGCAGA TTCAGATGGT GAAACAGATT GGAAAAGGTC GCTATGGGGA AGTTTGGATG
GGAAAGTGGC GTGGCGAAAA GGTAGCTGTG AAAGTGTTCT TCACCACAGA GGAAGCCAGC
TGGTTCAGAG AGACAGAAAT ATATCAGACA GTGTTGATGA GGCATGAAAA CATTTTGGGT
TTCATTGCTG CAGATATCAA AGGGACAGGG TCCTGGACCC AGTTGTACCT AATCACAGAC
TATCATGAAA ATGGTTCCCT TTATGATTAT CTGAAGTCCA CCACCCTAGA CGCTAAATCA
ATGCTGAAGT TAGCCTACTC TTCTGTCAGT GGCTTATGTC ATTTACACAC AGAAATCTTT
AGTACTCAAG GCAAACCAGC AATTGCCCAT CGAGATCTGA AAAGTAAAAA CATTCTGGTG
AAGAAAAATG GAACTTGCTG TATTGCTGAC CTGGGCCTGG CTGTTAAATT TATTAGTGAT
ACAAATGAAG TTGACATACC ACCTAACACT CGAGTTGGCA CCAAACGCTA TATGCCTCCA
GAAGTGTTGG ACGAGAGCTT GAACAGAAAT CACTTCCAGT CTTACATCAT GGCTGACATG
TATAGTTTTG GCCTCATCCT TTGGGAGGTT GCTAGGAGAT GTGTATCAGG AGGTATAGTG
GAAGAATACC AGCTTCCTTA TCATGACCTA GTGCCCAGTG ACCCCTCTTA TGAGGACATG
AGGGAGATTG TGTGCATCAA GAAGTTACGC CCCTCATTCC CAAACCGGTG GAGCAGTGAT
GAGTGTCTAA GGCAGATGGG AAAACTCATG ACAGAATGCT GGGCTCACAA TCCTGCATCA
AGGCTGACAG CCCTGCGGGT TAAGAAAACA CTTGCCAAAA TGTCAGAGTC CCAGGACATT
AAACTCTGA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OHu11503
Clone ID Related Accession (Same CDS sequence) XM_011532201.2 , NM_001256794.1 , XM_011532201.1 , XM_017008558.1 , XM_017008559.1 , XM_017008560.1 , XM_017008561.1 , NM_001203.2 , XM_011532202.1 , NM_001256792.1
Accession Version NM_001203.2 Latest version! Documents for ORF clone product in dufault vector
Sequence Information ORF Nucleotide Sequence (Length: 1509bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags COA
ORF Insert Method CloneEZ® Seamless cloning technology
Insert Structure linear
Update Date 2017-05-03
Organism Homo sapiens(Human)
Product bone morphogenetic protein receptor type-1B isoform b precursor
Comment REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AW299723.1, BC069796.1 and AC105395.1. This sequence is a reference standard in the RefSeqGene project. On or before Aug 31, 2013 this sequence version replaced XM_005263179.1, NM_001203.1. Transcript Variant: This variant (3) differs in the 5' UTR and coding sequence compared to variant 1. The resulting isoform (b) is shorter at the N-terminus compared to isoform a. Variants 2, 3, and 4 all encode isoform b. Sequence Note: This RefSeq record was created from transcript and genomic sequence data because no single transcript was available for the full length of the gene. The extent of this transcript is supported by transcript alignments and published data. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: U89326.1, SRR1660809.177216.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1968968, SAMEA2145245 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
1501
ATGCTTTTGC GAAGTGCAGG AAAATTAAAT GTGGGCACCA AGAAAGAGGA TGGTGAGAGT 
ACAGCCCCCA CCCCCCGTCC AAAGGTCTTG CGTTGTAAAT GCCACCACCA TTGTCCAGAA
GACTCAGTCA ACAATATTTG CAGCACAGAC GGATATTGTT TCACGATGAT AGAAGAGGAT
GACTCTGGGT TGCCTGTGGT CACTTCTGGT TGCCTAGGAC TAGAAGGCTC AGATTTTCAG
TGTCGGGACA CTCCCATTCC TCATCAAAGA AGATCAATTG AATGCTGCAC AGAAAGGAAC
GAATGTAATA AAGACCTACA CCCTACACTG CCTCCATTGA AAAACAGAGA TTTTGTTGAT
GGACCTATAC ACCACAGGGC TTTACTTATA TCTGTGACTG TCTGTAGTTT GCTCTTGGTC
CTTATCATAT TATTTTGTTA CTTCCGGTAT AAAAGACAAG AAACCAGACC TCGATACAGC
ATTGGGTTAG AACAGGATGA AACTTACATT CCTCCTGGAG AATCCCTGAG AGACTTAATT
GAGCAGTCTC AGAGCTCAGG AAGTGGATCA GGCCTCCCTC TGCTGGTCCA AAGGACTATA
GCTAAGCAGA TTCAGATGGT GAAACAGATT GGAAAAGGTC GCTATGGGGA AGTTTGGATG
GGAAAGTGGC GTGGCGAAAA GGTAGCTGTG AAAGTGTTCT TCACCACAGA GGAAGCCAGC
TGGTTCAGAG AGACAGAAAT ATATCAGACA GTGTTGATGA GGCATGAAAA CATTTTGGGT
TTCATTGCTG CAGATATCAA AGGGACAGGG TCCTGGACCC AGTTGTACCT AATCACAGAC
TATCATGAAA ATGGTTCCCT TTATGATTAT CTGAAGTCCA CCACCCTAGA CGCTAAATCA
ATGCTGAAGT TAGCCTACTC TTCTGTCAGT GGCTTATGTC ATTTACACAC AGAAATCTTT
AGTACTCAAG GCAAACCAGC AATTGCCCAT CGAGATCTGA AAAGTAAAAA CATTCTGGTG
AAGAAAAATG GAACTTGCTG TATTGCTGAC CTGGGCCTGG CTGTTAAATT TATTAGTGAT
ACAAATGAAG TTGACATACC ACCTAACACT CGAGTTGGCA CCAAACGCTA TATGCCTCCA
GAAGTGTTGG ACGAGAGCTT GAACAGAAAT CACTTCCAGT CTTACATCAT GGCTGACATG
TATAGTTTTG GCCTCATCCT TTGGGAGGTT GCTAGGAGAT GTGTATCAGG AGGTATAGTG
GAAGAATACC AGCTTCCTTA TCATGACCTA GTGCCCAGTG ACCCCTCTTA TGAGGACATG
AGGGAGATTG TGTGCATCAA GAAGTTACGC CCCTCATTCC CAAACCGGTG GAGCAGTGAT
GAGTGTCTAA GGCAGATGGG AAAACTCATG ACAGAATGCT GGGCTCACAA TCCTGCATCA
AGGCTGACAG CCCTGCGGGT TAAGAAAACA CTTGCCAAAA TGTCAGAGTC CCAGGACATT
AAACTCTGA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq NP_001194.1
CDS275..1783
Misc Feature(1)251..253
Misc Feature(2)362..604
Misc Feature(3)653..718
Misc Feature(4)866..1780
Misc Feature(5)887..1741
Misc Feature(6)order(902..916,926..928,959..961,965..967,1049..1051,1109..1120,1130..1132,1136..1138,1268..1270,1274..1276,1280..1285,1289..1291,1322..1324,1331..1333,1391..1402)
Misc Feature(7)order(902..922,926..928,959..961,965..967,1109..1114,1118..1120,1130..1132,1280..1285,1289..1291,1322..1324)
Misc Feature(8)order(914..916,1130..1132,1136..1138,1268..1270,1274..1276,1280..1282,1331..1333,1391..1402)
Misc Feature(9)order(995..1000,1007..1012,1019..1021,1064..1066,1070..1072)
Misc Feature(10)1319..1402
Exon (1)1..92
Exon (2)93..162
Exon (3)163..257
Exon (4)258..417
Exon (5)418..520
Exon (6)521..623
Exon (7)624..720
Exon (8)721..859
Exon (9)860..1052
Exon (10)1053..1350
Exon (11)1351..1526
Exon (12)1527..1657
Exon (13)1658..5560
Translation

Target ORF information:

RefSeq Version NM_001203.2
Organism Homo sapiens(Human)
Definition Homo sapiens bone morphogenetic protein receptor type 1B (BMPR1B), transcript variant 2, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
NM_001203.2

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
1501
ATGCTTTTGC GAAGTGCAGG AAAATTAAAT GTGGGCACCA AGAAAGAGGA TGGTGAGAGT 
ACAGCCCCCA CCCCCCGTCC AAAGGTCTTG CGTTGTAAAT GCCACCACCA TTGTCCAGAA
GACTCAGTCA ACAATATTTG CAGCACAGAC GGATATTGTT TCACGATGAT AGAAGAGGAT
GACTCTGGGT TGCCTGTGGT CACTTCTGGT TGCCTAGGAC TAGAAGGCTC AGATTTTCAG
TGTCGGGACA CTCCCATTCC TCATCAAAGA AGATCAATTG AATGCTGCAC AGAAAGGAAC
GAATGTAATA AAGACCTACA CCCTACACTG CCTCCATTGA AAAACAGAGA TTTTGTTGAT
GGACCTATAC ACCACAGGGC TTTACTTATA TCTGTGACTG TCTGTAGTTT GCTCTTGGTC
CTTATCATAT TATTTTGTTA CTTCCGGTAT AAAAGACAAG AAACCAGACC TCGATACAGC
ATTGGGTTAG AACAGGATGA AACTTACATT CCTCCTGGAG AATCCCTGAG AGACTTAATT
GAGCAGTCTC AGAGCTCAGG AAGTGGATCA GGCCTCCCTC TGCTGGTCCA AAGGACTATA
GCTAAGCAGA TTCAGATGGT GAAACAGATT GGAAAAGGTC GCTATGGGGA AGTTTGGATG
GGAAAGTGGC GTGGCGAAAA GGTAGCTGTG AAAGTGTTCT TCACCACAGA GGAAGCCAGC
TGGTTCAGAG AGACAGAAAT ATATCAGACA GTGTTGATGA GGCATGAAAA CATTTTGGGT
TTCATTGCTG CAGATATCAA AGGGACAGGG TCCTGGACCC AGTTGTACCT AATCACAGAC
TATCATGAAA ATGGTTCCCT TTATGATTAT CTGAAGTCCA CCACCCTAGA CGCTAAATCA
ATGCTGAAGT TAGCCTACTC TTCTGTCAGT GGCTTATGTC ATTTACACAC AGAAATCTTT
AGTACTCAAG GCAAACCAGC AATTGCCCAT CGAGATCTGA AAAGTAAAAA CATTCTGGTG
AAGAAAAATG GAACTTGCTG TATTGCTGAC CTGGGCCTGG CTGTTAAATT TATTAGTGAT
ACAAATGAAG TTGACATACC ACCTAACACT CGAGTTGGCA CCAAACGCTA TATGCCTCCA
GAAGTGTTGG ACGAGAGCTT GAACAGAAAT CACTTCCAGT CTTACATCAT GGCTGACATG
TATAGTTTTG GCCTCATCCT TTGGGAGGTT GCTAGGAGAT GTGTATCAGG AGGTATAGTG
GAAGAATACC AGCTTCCTTA TCATGACCTA GTGCCCAGTG ACCCCTCTTA TGAGGACATG
AGGGAGATTG TGTGCATCAA GAAGTTACGC CCCTCATTCC CAAACCGGTG GAGCAGTGAT
GAGTGTCTAA GGCAGATGGG AAAACTCATG ACAGAATGCT GGGCTCACAA TCCTGCATCA
AGGCTGACAG CCCTGCGGGT TAAGAAAACA CTTGCCAAAA TGTCAGAGTC CCAGGACATT
AAACTCTGA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OHu11503
Clone ID Related Accession (Same CDS sequence) XM_011532201.2 , NM_001256794.1 , XM_011532201.1 , XM_017008558.1 , XM_017008559.1 , XM_017008560.1 , XM_017008561.1 , NM_001203.2 , XM_011532202.1 , NM_001256792.1
Accession Version NM_001256792.1 Latest version! Documents for ORF clone product in dufault vector
Sequence Information ORF Nucleotide Sequence (Length: 1509bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags COA
ORF Insert Method CloneEZ® Seamless cloning technology
Insert Structure linear
Update Date 2016-10-07
Organism Homo sapiens(Human)
Product bone morphogenetic protein receptor type-1B isoform b precursor
Comment REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AK313642.1, AC092609.2 and AC105395.1. Transcript Variant: This variant (3) differs in the 5' UTR and coding sequence compared to variant 1. The resulting isoform (b) is shorter at the N-terminus compared to isoform a. Variants 2, 3, and 4 all encode isoform b. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AK313642.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1970526, SAMEA2145743 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
1501
ATGCTTTTGC GAAGTGCAGG AAAATTAAAT GTGGGCACCA AGAAAGAGGA TGGTGAGAGT 
ACAGCCCCCA CCCCCCGTCC AAAGGTCTTG CGTTGTAAAT GCCACCACCA TTGTCCAGAA
GACTCAGTCA ACAATATTTG CAGCACAGAC GGATATTGTT TCACGATGAT AGAAGAGGAT
GACTCTGGGT TGCCTGTGGT CACTTCTGGT TGCCTAGGAC TAGAAGGCTC AGATTTTCAG
TGTCGGGACA CTCCCATTCC TCATCAAAGA AGATCAATTG AATGCTGCAC AGAAAGGAAC
GAATGTAATA AAGACCTACA CCCTACACTG CCTCCATTGA AAAACAGAGA TTTTGTTGAT
GGACCTATAC ACCACAGGGC TTTACTTATA TCTGTGACTG TCTGTAGTTT GCTCTTGGTC
CTTATCATAT TATTTTGTTA CTTCCGGTAT AAAAGACAAG AAACCAGACC TCGATACAGC
ATTGGGTTAG AACAGGATGA AACTTACATT CCTCCTGGAG AATCCCTGAG AGACTTAATT
GAGCAGTCTC AGAGCTCAGG AAGTGGATCA GGCCTCCCTC TGCTGGTCCA AAGGACTATA
GCTAAGCAGA TTCAGATGGT GAAACAGATT GGAAAAGGTC GCTATGGGGA AGTTTGGATG
GGAAAGTGGC GTGGCGAAAA GGTAGCTGTG AAAGTGTTCT TCACCACAGA GGAAGCCAGC
TGGTTCAGAG AGACAGAAAT ATATCAGACA GTGTTGATGA GGCATGAAAA CATTTTGGGT
TTCATTGCTG CAGATATCAA AGGGACAGGG TCCTGGACCC AGTTGTACCT AATCACAGAC
TATCATGAAA ATGGTTCCCT TTATGATTAT CTGAAGTCCA CCACCCTAGA CGCTAAATCA
ATGCTGAAGT TAGCCTACTC TTCTGTCAGT GGCTTATGTC ATTTACACAC AGAAATCTTT
AGTACTCAAG GCAAACCAGC AATTGCCCAT CGAGATCTGA AAAGTAAAAA CATTCTGGTG
AAGAAAAATG GAACTTGCTG TATTGCTGAC CTGGGCCTGG CTGTTAAATT TATTAGTGAT
ACAAATGAAG TTGACATACC ACCTAACACT CGAGTTGGCA CCAAACGCTA TATGCCTCCA
GAAGTGTTGG ACGAGAGCTT GAACAGAAAT CACTTCCAGT CTTACATCAT GGCTGACATG
TATAGTTTTG GCCTCATCCT TTGGGAGGTT GCTAGGAGAT GTGTATCAGG AGGTATAGTG
GAAGAATACC AGCTTCCTTA TCATGACCTA GTGCCCAGTG ACCCCTCTTA TGAGGACATG
AGGGAGATTG TGTGCATCAA GAAGTTACGC CCCTCATTCC CAAACCGGTG GAGCAGTGAT
GAGTGTCTAA GGCAGATGGG AAAACTCATG ACAGAATGCT GGGCTCACAA TCCTGCATCA
AGGCTGACAG CCCTGCGGGT TAAGAAAACA CTTGCCAAAA TGTCAGAGTC CCAGGACATT
AAACTCTGA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq NP_001243721.1
CDS171..1679
Misc Feature(1)111..113
Misc Feature(2)258..500
Misc Feature(3)549..614
Misc Feature(4)762..1676
Misc Feature(5)783..1637
Misc Feature(6)order(798..812,822..824,855..857,861..863,945..947,1005..1016,1026..1028,1032..1034,1164..1166,1170..1172,1176..1181,1185..1187,1218..1220,1227..1229,1287..1298)
Misc Feature(7)order(798..818,822..824,855..857,861..863,1005..1010,1014..1016,1026..1028,1176..1181,1185..1187,1218..1220)
Misc Feature(8)order(810..812,1026..1028,1032..1034,1164..1166,1170..1172,1176..1178,1227..1229,1287..1298)
Misc Feature(9)order(891..896,903..908,915..917,960..962,966..968)
Misc Feature(10)1215..1298
Exon (1)1..153
Exon (2)154..313
Exon (3)314..416
Exon (4)417..519
Exon (5)520..616
Exon (6)617..755
Exon (7)756..948
Exon (8)949..1246
Exon (9)1247..1422
Exon (10)1423..1553
Exon (11)1554..5456
Translation

Target ORF information:

RefSeq Version NM_001256792.1
Organism Homo sapiens(Human)
Definition Homo sapiens bone morphogenetic protein receptor type 1B (BMPR1B), transcript variant 3, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
NM_001256792.1

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
1501
ATGCTTTTGC GAAGTGCAGG AAAATTAAAT GTGGGCACCA AGAAAGAGGA TGGTGAGAGT 
ACAGCCCCCA CCCCCCGTCC AAAGGTCTTG CGTTGTAAAT GCCACCACCA TTGTCCAGAA
GACTCAGTCA ACAATATTTG CAGCACAGAC GGATATTGTT TCACGATGAT AGAAGAGGAT
GACTCTGGGT TGCCTGTGGT CACTTCTGGT TGCCTAGGAC TAGAAGGCTC AGATTTTCAG
TGTCGGGACA CTCCCATTCC TCATCAAAGA AGATCAATTG AATGCTGCAC AGAAAGGAAC
GAATGTAATA AAGACCTACA CCCTACACTG CCTCCATTGA AAAACAGAGA TTTTGTTGAT
GGACCTATAC ACCACAGGGC TTTACTTATA TCTGTGACTG TCTGTAGTTT GCTCTTGGTC
CTTATCATAT TATTTTGTTA CTTCCGGTAT AAAAGACAAG AAACCAGACC TCGATACAGC
ATTGGGTTAG AACAGGATGA AACTTACATT CCTCCTGGAG AATCCCTGAG AGACTTAATT
GAGCAGTCTC AGAGCTCAGG AAGTGGATCA GGCCTCCCTC TGCTGGTCCA AAGGACTATA
GCTAAGCAGA TTCAGATGGT GAAACAGATT GGAAAAGGTC GCTATGGGGA AGTTTGGATG
GGAAAGTGGC GTGGCGAAAA GGTAGCTGTG AAAGTGTTCT TCACCACAGA GGAAGCCAGC
TGGTTCAGAG AGACAGAAAT ATATCAGACA GTGTTGATGA GGCATGAAAA CATTTTGGGT
TTCATTGCTG CAGATATCAA AGGGACAGGG TCCTGGACCC AGTTGTACCT AATCACAGAC
TATCATGAAA ATGGTTCCCT TTATGATTAT CTGAAGTCCA CCACCCTAGA CGCTAAATCA
ATGCTGAAGT TAGCCTACTC TTCTGTCAGT GGCTTATGTC ATTTACACAC AGAAATCTTT
AGTACTCAAG GCAAACCAGC AATTGCCCAT CGAGATCTGA AAAGTAAAAA CATTCTGGTG
AAGAAAAATG GAACTTGCTG TATTGCTGAC CTGGGCCTGG CTGTTAAATT TATTAGTGAT
ACAAATGAAG TTGACATACC ACCTAACACT CGAGTTGGCA CCAAACGCTA TATGCCTCCA
GAAGTGTTGG ACGAGAGCTT GAACAGAAAT CACTTCCAGT CTTACATCAT GGCTGACATG
TATAGTTTTG GCCTCATCCT TTGGGAGGTT GCTAGGAGAT GTGTATCAGG AGGTATAGTG
GAAGAATACC AGCTTCCTTA TCATGACCTA GTGCCCAGTG ACCCCTCTTA TGAGGACATG
AGGGAGATTG TGTGCATCAA GAAGTTACGC CCCTCATTCC CAAACCGGTG GAGCAGTGAT
GAGTGTCTAA GGCAGATGGG AAAACTCATG ACAGAATGCT GGGCTCACAA TCCTGCATCA
AGGCTGACAG CCCTGCGGGT TAAGAAAACA CTTGCCAAAA TGTCAGAGTC CCAGGACATT
AAACTCTGA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OHu12264
Clone ID Related Accession (Same CDS sequence) NM_001256793.1
Accession Version NM_001256793.1 Latest version! Documents for ORF clone product in dufault vector
Sequence Information ORF Nucleotide Sequence (Length: 1599bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags COA
ORF Insert Method CloneEZ® Seamless cloning technology
Insert Structure linear
Update Date 2016-10-07
Organism Homo sapiens(Human)
Product bone morphogenetic protein receptor type-1B isoform a precursor
Comment REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AK299930.1 and AC105395.1. Transcript Variant: This variant (1) encodes the longer isoform (a). Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AK299930.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2145743, SAMEA2145774 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
1501
1561
ATGGGTTGGC TGGAAGAACT AAACTGGCAG CTTCACATTT TCTTGCTCAT TCTTCTCTCT 
ATGCACACAA GGGCAAACTT CCTTGATAAC ATGCTTTTGC GAAGTGCAGG AAAATTAAAT
GTGGGCACCA AGAAAGAGGA TGGTGAGAGT ACAGCCCCCA CCCCCCGTCC AAAGGTCTTG
CGTTGTAAAT GCCACCACCA TTGTCCAGAA GACTCAGTCA ACAATATTTG CAGCACAGAC
GGATATTGTT TCACGATGAT AGAAGAGGAT GACTCTGGGT TGCCTGTGGT CACTTCTGGT
TGCCTAGGAC TAGAAGGCTC AGATTTTCAG TGTCGGGACA CTCCCATTCC TCATCAAAGA
AGATCAATTG AATGCTGCAC AGAAAGGAAC GAATGTAATA AAGACCTACA CCCTACACTG
CCTCCATTGA AAAACAGAGA TTTTGTTGAT GGACCTATAC ACCACAGGGC TTTACTTATA
TCTGTGACTG TCTGTAGTTT GCTCTTGGTC CTTATCATAT TATTTTGTTA CTTCCGGTAT
AAAAGACAAG AAACCAGACC TCGATACAGC ATTGGGTTAG AACAGGATGA AACTTACATT
CCTCCTGGAG AATCCCTGAG AGACTTAATT GAGCAGTCTC AGAGCTCAGG AAGTGGATCA
GGCCTCCCTC TGCTGGTCCA AAGGACTATA GCTAAGCAGA TTCAGATGGT GAAACAGATT
GGAAAAGGTC GCTATGGGGA AGTTTGGATG GGAAAGTGGC GTGGCGAAAA GGTAGCTGTG
AAAGTGTTCT TCACCACAGA GGAAGCCAGC TGGTTCAGAG AGACAGAAAT ATATCAGACA
GTGTTGATGA GGCATGAAAA CATTTTGGGT TTCATTGCTG CAGATATCAA AGGGACAGGG
TCCTGGACCC AGTTGTACCT AATCACAGAC TATCATGAAA ATGGTTCCCT TTATGATTAT
CTGAAGTCCA CCACCCTAGA CGCTAAATCA ATGCTGAAGT TAGCCTACTC TTCTGTCAGT
GGCTTATGTC ATTTACACAC AGAAATCTTT AGTACTCAAG GCAAACCAGC AATTGCCCAT
CGAGATCTGA AAAGTAAAAA CATTCTGGTG AAGAAAAATG GAACTTGCTG TATTGCTGAC
CTGGGCCTGG CTGTTAAATT TATTAGTGAT ACAAATGAAG TTGACATACC ACCTAACACT
CGAGTTGGCA CCAAACGCTA TATGCCTCCA GAAGTGTTGG ACGAGAGCTT GAACAGAAAT
CACTTCCAGT CTTACATCAT GGCTGACATG TATAGTTTTG GCCTCATCCT TTGGGAGGTT
GCTAGGAGAT GTGTATCAGG AGGTATAGTG GAAGAATACC AGCTTCCTTA TCATGACCTA
GTGCCCAGTG ACCCCTCTTA TGAGGACATG AGGGAGATTG TGTGCATCAA GAAGTTACGC
CCCTCATTCC CAAACCGGTG GAGCAGTGAT GAGTGTCTAA GGCAGATGGG AAAACTCATG
ACAGAATGCT GGGCTCACAA TCCTGCATCA AGGCTGACAG CCCTGCGGGT TAAGAAAACA
CTTGCCAAAA TGTCAGAGTC CCAGGACATT AAACTCTGA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq NP_001243722.1
CDS22..1620
Misc Feature(1)199..441
Misc Feature(2)703..1617
Misc Feature(3)724..1578
Misc Feature(4)order(739..753,763..765,796..798,802..804,886..888,946..957,967..969,973..975,1105..1107,1111..1113,1117..1122,1126..1128,1159..1161,1168..1170,1228..1239)
Misc Feature(5)order(739..759,763..765,796..798,802..804,946..951,955..957,967..969,1117..1122,1126..1128,1159..1161)
Misc Feature(6)order(751..753,967..969,973..975,1105..1107,1111..1113,1117..1119,1168..1170,1228..1239)
Misc Feature(7)order(832..837,844..849,856..858,901..903,907..909)
Misc Feature(8)1156..1239
Exon (1)1..94
Exon (2)95..254
Exon (3)255..357
Exon (4)358..460
Exon (5)461..557
Exon (6)558..696
Exon (7)697..889
Exon (8)890..1187
Exon (9)1188..1363
Exon (10)1364..1494
Exon (11)1495..5397
Translation

Target ORF information:

RefSeq Version NM_001256793.1
Organism Homo sapiens(Human)
Definition Homo sapiens bone morphogenetic protein receptor type 1B (BMPR1B), transcript variant 1, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
NM_001256793.1

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
1501
1561
ATGGGTTGGC TGGAAGAACT AAACTGGCAG CTTCACATTT TCTTGCTCAT TCTTCTCTCT 
ATGCACACAA GGGCAAACTT CCTTGATAAC ATGCTTTTGC GAAGTGCAGG AAAATTAAAT
GTGGGCACCA AGAAAGAGGA TGGTGAGAGT ACAGCCCCCA CCCCCCGTCC AAAGGTCTTG
CGTTGTAAAT GCCACCACCA TTGTCCAGAA GACTCAGTCA ACAATATTTG CAGCACAGAC
GGATATTGTT TCACGATGAT AGAAGAGGAT GACTCTGGGT TGCCTGTGGT CACTTCTGGT
TGCCTAGGAC TAGAAGGCTC AGATTTTCAG TGTCGGGACA CTCCCATTCC TCATCAAAGA
AGATCAATTG AATGCTGCAC AGAAAGGAAC GAATGTAATA AAGACCTACA CCCTACACTG
CCTCCATTGA AAAACAGAGA TTTTGTTGAT GGACCTATAC ACCACAGGGC TTTACTTATA
TCTGTGACTG TCTGTAGTTT GCTCTTGGTC CTTATCATAT TATTTTGTTA CTTCCGGTAT
AAAAGACAAG AAACCAGACC TCGATACAGC ATTGGGTTAG AACAGGATGA AACTTACATT
CCTCCTGGAG AATCCCTGAG AGACTTAATT GAGCAGTCTC AGAGCTCAGG AAGTGGATCA
GGCCTCCCTC TGCTGGTCCA AAGGACTATA GCTAAGCAGA TTCAGATGGT GAAACAGATT
GGAAAAGGTC GCTATGGGGA AGTTTGGATG GGAAAGTGGC GTGGCGAAAA GGTAGCTGTG
AAAGTGTTCT TCACCACAGA GGAAGCCAGC TGGTTCAGAG AGACAGAAAT ATATCAGACA
GTGTTGATGA GGCATGAAAA CATTTTGGGT TTCATTGCTG CAGATATCAA AGGGACAGGG
TCCTGGACCC AGTTGTACCT AATCACAGAC TATCATGAAA ATGGTTCCCT TTATGATTAT
CTGAAGTCCA CCACCCTAGA CGCTAAATCA ATGCTGAAGT TAGCCTACTC TTCTGTCAGT
GGCTTATGTC ATTTACACAC AGAAATCTTT AGTACTCAAG GCAAACCAGC AATTGCCCAT
CGAGATCTGA AAAGTAAAAA CATTCTGGTG AAGAAAAATG GAACTTGCTG TATTGCTGAC
CTGGGCCTGG CTGTTAAATT TATTAGTGAT ACAAATGAAG TTGACATACC ACCTAACACT
CGAGTTGGCA CCAAACGCTA TATGCCTCCA GAAGTGTTGG ACGAGAGCTT GAACAGAAAT
CACTTCCAGT CTTACATCAT GGCTGACATG TATAGTTTTG GCCTCATCCT TTGGGAGGTT
GCTAGGAGAT GTGTATCAGG AGGTATAGTG GAAGAATACC AGCTTCCTTA TCATGACCTA
GTGCCCAGTG ACCCCTCTTA TGAGGACATG AGGGAGATTG TGTGCATCAA GAAGTTACGC
CCCTCATTCC CAAACCGGTG GAGCAGTGAT GAGTGTCTAA GGCAGATGGG AAAACTCATG
ACAGAATGCT GGGCTCACAA TCCTGCATCA AGGCTGACAG CCCTGCGGGT TAAGAAAACA
CTTGCCAAAA TGTCAGAGTC CCAGGACATT AAACTCTGA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OHu11503
Clone ID Related Accession (Same CDS sequence) XM_011532201.2 , NM_001256794.1 , XM_011532201.1 , XM_017008558.1 , XM_017008559.1 , XM_017008560.1 , XM_017008561.1 , NM_001203.2 , XM_011532202.1 , NM_001256792.1
Accession Version XM_011532201.2 Latest version! Documents for ORF clone product in dufault vector
Sequence Information ORF Nucleotide Sequence (Length: 1509bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags COA
ORF Insert Method CloneEZ® Seamless cloning technology
Insert Structure linear
Update Date 2016-06-06
Organism Homo sapiens(Human)
Product bone morphogenetic protein receptor type-1B isoform X1
Comment MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000004.12) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 6, 2016 this sequence version replaced XM_011532201.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Homo sapiens Annotation Release 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
1501
ATGCTTTTGC GAAGTGCAGG AAAATTAAAT GTGGGCACCA AGAAAGAGGA TGGTGAGAGT 
ACAGCCCCCA CCCCCCGTCC AAAGGTCTTG CGTTGTAAAT GCCACCACCA TTGTCCAGAA
GACTCAGTCA ACAATATTTG CAGCACAGAC GGATATTGTT TCACGATGAT AGAAGAGGAT
GACTCTGGGT TGCCTGTGGT CACTTCTGGT TGCCTAGGAC TAGAAGGCTC AGATTTTCAG
TGTCGGGACA CTCCCATTCC TCATCAAAGA AGATCAATTG AATGCTGCAC AGAAAGGAAC
GAATGTAATA AAGACCTACA CCCTACACTG CCTCCATTGA AAAACAGAGA TTTTGTTGAT
GGACCTATAC ACCACAGGGC TTTACTTATA TCTGTGACTG TCTGTAGTTT GCTCTTGGTC
CTTATCATAT TATTTTGTTA CTTCCGGTAT AAAAGACAAG AAACCAGACC TCGATACAGC
ATTGGGTTAG AACAGGATGA AACTTACATT CCTCCTGGAG AATCCCTGAG AGACTTAATT
GAGCAGTCTC AGAGCTCAGG AAGTGGATCA GGCCTCCCTC TGCTGGTCCA AAGGACTATA
GCTAAGCAGA TTCAGATGGT GAAACAGATT GGAAAAGGTC GCTATGGGGA AGTTTGGATG
GGAAAGTGGC GTGGCGAAAA GGTAGCTGTG AAAGTGTTCT TCACCACAGA GGAAGCCAGC
TGGTTCAGAG AGACAGAAAT ATATCAGACA GTGTTGATGA GGCATGAAAA CATTTTGGGT
TTCATTGCTG CAGATATCAA AGGGACAGGG TCCTGGACCC AGTTGTACCT AATCACAGAC
TATCATGAAA ATGGTTCCCT TTATGATTAT CTGAAGTCCA CCACCCTAGA CGCTAAATCA
ATGCTGAAGT TAGCCTACTC TTCTGTCAGT GGCTTATGTC ATTTACACAC AGAAATCTTT
AGTACTCAAG GCAAACCAGC AATTGCCCAT CGAGATCTGA AAAGTAAAAA CATTCTGGTG
AAGAAAAATG GAACTTGCTG TATTGCTGAC CTGGGCCTGG CTGTTAAATT TATTAGTGAT
ACAAATGAAG TTGACATACC ACCTAACACT CGAGTTGGCA CCAAACGCTA TATGCCTCCA
GAAGTGTTGG ACGAGAGCTT GAACAGAAAT CACTTCCAGT CTTACATCAT GGCTGACATG
TATAGTTTTG GCCTCATCCT TTGGGAGGTT GCTAGGAGAT GTGTATCAGG AGGTATAGTG
GAAGAATACC AGCTTCCTTA TCATGACCTA GTGCCCAGTG ACCCCTCTTA TGAGGACATG
AGGGAGATTG TGTGCATCAA GAAGTTACGC CCCTCATTCC CAAACCGGTG GAGCAGTGAT
GAGTGTCTAA GGCAGATGGG AAAACTCATG ACAGAATGCT GGGCTCACAA TCCTGCATCA
AGGCTGACAG CCCTGCGGGT TAAGAAAACA CTTGCCAAAA TGTCAGAGTC CCAGGACATT
AAACTCTGA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq XP_011530503.1
CDS154..1662
Misc Feature(1)241..483
Misc Feature(2)745..1659
Misc Feature(3)766..1620
Misc Feature(4)order(781..795,805..807,838..840,844..846,928..930,988..999,1009..1011,1015..1017,1147..1149,1153..1155,1159..1164,1168..1170,1201..1203,1210..1212,1270..1281)
Misc Feature(5)order(781..801,805..807,838..840,844..846,988..993,997..999,1009..1011,1159..1164,1168..1170,1201..1203)
Misc Feature(6)order(793..795,1009..1011,1015..1017,1147..1149,1153..1155,1159..1161,1210..1212,1270..1281)
Misc Feature(7)order(874..879,886..891,898..900,943..945,949..951)
Misc Feature(8)1198..1281
Translation

Target ORF information:

RefSeq Version XM_011532201.2
Organism Homo sapiens(Human)
Definition Homo sapiens bone morphogenetic protein receptor type 1B (BMPR1B), transcript variant X5, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
XM_011532201.2

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
1501
ATGCTTTTGC GAAGTGCAGG AAAATTAAAT GTGGGCACCA AGAAAGAGGA TGGTGAGAGT 
ACAGCCCCCA CCCCCCGTCC AAAGGTCTTG CGTTGTAAAT GCCACCACCA TTGTCCAGAA
GACTCAGTCA ACAATATTTG CAGCACAGAC GGATATTGTT TCACGATGAT AGAAGAGGAT
GACTCTGGGT TGCCTGTGGT CACTTCTGGT TGCCTAGGAC TAGAAGGCTC AGATTTTCAG
TGTCGGGACA CTCCCATTCC TCATCAAAGA AGATCAATTG AATGCTGCAC AGAAAGGAAC
GAATGTAATA AAGACCTACA CCCTACACTG CCTCCATTGA AAAACAGAGA TTTTGTTGAT
GGACCTATAC ACCACAGGGC TTTACTTATA TCTGTGACTG TCTGTAGTTT GCTCTTGGTC
CTTATCATAT TATTTTGTTA CTTCCGGTAT AAAAGACAAG AAACCAGACC TCGATACAGC
ATTGGGTTAG AACAGGATGA AACTTACATT CCTCCTGGAG AATCCCTGAG AGACTTAATT
GAGCAGTCTC AGAGCTCAGG AAGTGGATCA GGCCTCCCTC TGCTGGTCCA AAGGACTATA
GCTAAGCAGA TTCAGATGGT GAAACAGATT GGAAAAGGTC GCTATGGGGA AGTTTGGATG
GGAAAGTGGC GTGGCGAAAA GGTAGCTGTG AAAGTGTTCT TCACCACAGA GGAAGCCAGC
TGGTTCAGAG AGACAGAAAT ATATCAGACA GTGTTGATGA GGCATGAAAA CATTTTGGGT
TTCATTGCTG CAGATATCAA AGGGACAGGG TCCTGGACCC AGTTGTACCT AATCACAGAC
TATCATGAAA ATGGTTCCCT TTATGATTAT CTGAAGTCCA CCACCCTAGA CGCTAAATCA
ATGCTGAAGT TAGCCTACTC TTCTGTCAGT GGCTTATGTC ATTTACACAC AGAAATCTTT
AGTACTCAAG GCAAACCAGC AATTGCCCAT CGAGATCTGA AAAGTAAAAA CATTCTGGTG
AAGAAAAATG GAACTTGCTG TATTGCTGAC CTGGGCCTGG CTGTTAAATT TATTAGTGAT
ACAAATGAAG TTGACATACC ACCTAACACT CGAGTTGGCA CCAAACGCTA TATGCCTCCA
GAAGTGTTGG ACGAGAGCTT GAACAGAAAT CACTTCCAGT CTTACATCAT GGCTGACATG
TATAGTTTTG GCCTCATCCT TTGGGAGGTT GCTAGGAGAT GTGTATCAGG AGGTATAGTG
GAAGAATACC AGCTTCCTTA TCATGACCTA GTGCCCAGTG ACCCCTCTTA TGAGGACATG
AGGGAGATTG TGTGCATCAA GAAGTTACGC CCCTCATTCC CAAACCGGTG GAGCAGTGAT
GAGTGTCTAA GGCAGATGGG AAAACTCATG ACAGAATGCT GGGCTCACAA TCCTGCATCA
AGGCTGACAG CCCTGCGGGT TAAGAAAACA CTTGCCAAAA TGTCAGAGTC CCAGGACATT
AAACTCTGA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OHu11503
Clone ID Related Accession (Same CDS sequence) XM_011532201.2 , NM_001256794.1 , XM_011532201.1 , XM_017008558.1 , XM_017008559.1 , XM_017008560.1 , XM_017008561.1 , NM_001203.2 , XM_011532202.1 , NM_001256792.1
Accession Version XM_011532201.1 Documents for ORF clone product in dufault vector
Sequence Information ORF Nucleotide Sequence (Length: 1509bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags COA
ORF Insert Method CloneEZ® Seamless cloning technology
Insert Structure linear
Update Date 2015-03-12
Organism Homo sapiens(Human)
Product bone morphogenetic protein receptor type-1B isoform X1
Comment

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
1501
ATGCTTTTGC GAAGTGCAGG AAAATTAAAT GTGGGCACCA AGAAAGAGGA TGGTGAGAGT 
ACAGCCCCCA CCCCCCGTCC AAAGGTCTTG CGTTGTAAAT GCCACCACCA TTGTCCAGAA
GACTCAGTCA ACAATATTTG CAGCACAGAC GGATATTGTT TCACGATGAT AGAAGAGGAT
GACTCTGGGT TGCCTGTGGT CACTTCTGGT TGCCTAGGAC TAGAAGGCTC AGATTTTCAG
TGTCGGGACA CTCCCATTCC TCATCAAAGA AGATCAATTG AATGCTGCAC AGAAAGGAAC
GAATGTAATA AAGACCTACA CCCTACACTG CCTCCATTGA AAAACAGAGA TTTTGTTGAT
GGACCTATAC ACCACAGGGC TTTACTTATA TCTGTGACTG TCTGTAGTTT GCTCTTGGTC
CTTATCATAT TATTTTGTTA CTTCCGGTAT AAAAGACAAG AAACCAGACC TCGATACAGC
ATTGGGTTAG AACAGGATGA AACTTACATT CCTCCTGGAG AATCCCTGAG AGACTTAATT
GAGCAGTCTC AGAGCTCAGG AAGTGGATCA GGCCTCCCTC TGCTGGTCCA AAGGACTATA
GCTAAGCAGA TTCAGATGGT GAAACAGATT GGAAAAGGTC GCTATGGGGA AGTTTGGATG
GGAAAGTGGC GTGGCGAAAA GGTAGCTGTG AAAGTGTTCT TCACCACAGA GGAAGCCAGC
TGGTTCAGAG AGACAGAAAT ATATCAGACA GTGTTGATGA GGCATGAAAA CATTTTGGGT
TTCATTGCTG CAGATATCAA AGGGACAGGG TCCTGGACCC AGTTGTACCT AATCACAGAC
TATCATGAAA ATGGTTCCCT TTATGATTAT CTGAAGTCCA CCACCCTAGA CGCTAAATCA
ATGCTGAAGT TAGCCTACTC TTCTGTCAGT GGCTTATGTC ATTTACACAC AGAAATCTTT
AGTACTCAAG GCAAACCAGC AATTGCCCAT CGAGATCTGA AAAGTAAAAA CATTCTGGTG
AAGAAAAATG GAACTTGCTG TATTGCTGAC CTGGGCCTGG CTGTTAAATT TATTAGTGAT
ACAAATGAAG TTGACATACC ACCTAACACT CGAGTTGGCA CCAAACGCTA TATGCCTCCA
GAAGTGTTGG ACGAGAGCTT GAACAGAAAT CACTTCCAGT CTTACATCAT GGCTGACATG
TATAGTTTTG GCCTCATCCT TTGGGAGGTT GCTAGGAGAT GTGTATCAGG AGGTATAGTG
GAAGAATACC AGCTTCCTTA TCATGACCTA GTGCCCAGTG ACCCCTCTTA TGAGGACATG
AGGGAGATTG TGTGCATCAA GAAGTTACGC CCCTCATTCC CAAACCGGTG GAGCAGTGAT
GAGTGTCTAA GGCAGATGGG AAAACTCATG ACAGAATGCT GGGCTCACAA TCCTGCATCA
AGGCTGACAG CCCTGCGGGT TAAGAAAACA CTTGCCAAAA TGTCAGAGTC CCAGGACATT
AAACTCTGA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq XP_011530503.1
Translation

Target ORF information:

RefSeq Version XM_011532201.1
Organism Homo sapiens(Human)
Definition Homo sapiens bone morphogenetic protein receptor, type IB (BMPR1B), transcript variant X1, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
XM_011532201.1

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
1501
ATGCTTTTGC GAAGTGCAGG AAAATTAAAT GTGGGCACCA AGAAAGAGGA TGGTGAGAGT 
ACAGCCCCCA CCCCCCGTCC AAAGGTCTTG CGTTGTAAAT GCCACCACCA TTGTCCAGAA
GACTCAGTCA ACAATATTTG CAGCACAGAC GGATATTGTT TCACGATGAT AGAAGAGGAT
GACTCTGGGT TGCCTGTGGT CACTTCTGGT TGCCTAGGAC TAGAAGGCTC AGATTTTCAG
TGTCGGGACA CTCCCATTCC TCATCAAAGA AGATCAATTG AATGCTGCAC AGAAAGGAAC
GAATGTAATA AAGACCTACA CCCTACACTG CCTCCATTGA AAAACAGAGA TTTTGTTGAT
GGACCTATAC ACCACAGGGC TTTACTTATA TCTGTGACTG TCTGTAGTTT GCTCTTGGTC
CTTATCATAT TATTTTGTTA CTTCCGGTAT AAAAGACAAG AAACCAGACC TCGATACAGC
ATTGGGTTAG AACAGGATGA AACTTACATT CCTCCTGGAG AATCCCTGAG AGACTTAATT
GAGCAGTCTC AGAGCTCAGG AAGTGGATCA GGCCTCCCTC TGCTGGTCCA AAGGACTATA
GCTAAGCAGA TTCAGATGGT GAAACAGATT GGAAAAGGTC GCTATGGGGA AGTTTGGATG
GGAAAGTGGC GTGGCGAAAA GGTAGCTGTG AAAGTGTTCT TCACCACAGA GGAAGCCAGC
TGGTTCAGAG AGACAGAAAT ATATCAGACA GTGTTGATGA GGCATGAAAA CATTTTGGGT
TTCATTGCTG CAGATATCAA AGGGACAGGG TCCTGGACCC AGTTGTACCT AATCACAGAC
TATCATGAAA ATGGTTCCCT TTATGATTAT CTGAAGTCCA CCACCCTAGA CGCTAAATCA
ATGCTGAAGT TAGCCTACTC TTCTGTCAGT GGCTTATGTC ATTTACACAC AGAAATCTTT
AGTACTCAAG GCAAACCAGC AATTGCCCAT CGAGATCTGA AAAGTAAAAA CATTCTGGTG
AAGAAAAATG GAACTTGCTG TATTGCTGAC CTGGGCCTGG CTGTTAAATT TATTAGTGAT
ACAAATGAAG TTGACATACC ACCTAACACT CGAGTTGGCA CCAAACGCTA TATGCCTCCA
GAAGTGTTGG ACGAGAGCTT GAACAGAAAT CACTTCCAGT CTTACATCAT GGCTGACATG
TATAGTTTTG GCCTCATCCT TTGGGAGGTT GCTAGGAGAT GTGTATCAGG AGGTATAGTG
GAAGAATACC AGCTTCCTTA TCATGACCTA GTGCCCAGTG ACCCCTCTTA TGAGGACATG
AGGGAGATTG TGTGCATCAA GAAGTTACGC CCCTCATTCC CAAACCGGTG GAGCAGTGAT
GAGTGTCTAA GGCAGATGGG AAAACTCATG ACAGAATGCT GGGCTCACAA TCCTGCATCA
AGGCTGACAG CCCTGCGGGT TAAGAAAACA CTTGCCAAAA TGTCAGAGTC CCAGGACATT
AAACTCTGA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OHu11503
Clone ID Related Accession (Same CDS sequence) XM_011532201.2 , NM_001256794.1 , XM_011532201.1 , XM_017008558.1 , XM_017008559.1 , XM_017008560.1 , XM_017008561.1 , NM_001203.2 , XM_011532202.1 , NM_001256792.1
Accession Version XM_017008558.1 Latest version! Documents for ORF clone product in dufault vector
Sequence Information ORF Nucleotide Sequence (Length: 1509bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags COA
ORF Insert Method CloneEZ® Seamless cloning technology
Insert Structure linear
Update Date 2016-06-06
Organism Homo sapiens(Human)
Product bone morphogenetic protein receptor type-1B isoform X1
Comment MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000004.12) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Homo sapiens Annotation Release 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
1501
ATGCTTTTGC GAAGTGCAGG AAAATTAAAT GTGGGCACCA AGAAAGAGGA TGGTGAGAGT 
ACAGCCCCCA CCCCCCGTCC AAAGGTCTTG CGTTGTAAAT GCCACCACCA TTGTCCAGAA
GACTCAGTCA ACAATATTTG CAGCACAGAC GGATATTGTT TCACGATGAT AGAAGAGGAT
GACTCTGGGT TGCCTGTGGT CACTTCTGGT TGCCTAGGAC TAGAAGGCTC AGATTTTCAG
TGTCGGGACA CTCCCATTCC TCATCAAAGA AGATCAATTG AATGCTGCAC AGAAAGGAAC
GAATGTAATA AAGACCTACA CCCTACACTG CCTCCATTGA AAAACAGAGA TTTTGTTGAT
GGACCTATAC ACCACAGGGC TTTACTTATA TCTGTGACTG TCTGTAGTTT GCTCTTGGTC
CTTATCATAT TATTTTGTTA CTTCCGGTAT AAAAGACAAG AAACCAGACC TCGATACAGC
ATTGGGTTAG AACAGGATGA AACTTACATT CCTCCTGGAG AATCCCTGAG AGACTTAATT
GAGCAGTCTC AGAGCTCAGG AAGTGGATCA GGCCTCCCTC TGCTGGTCCA AAGGACTATA
GCTAAGCAGA TTCAGATGGT GAAACAGATT GGAAAAGGTC GCTATGGGGA AGTTTGGATG
GGAAAGTGGC GTGGCGAAAA GGTAGCTGTG AAAGTGTTCT TCACCACAGA GGAAGCCAGC
TGGTTCAGAG AGACAGAAAT ATATCAGACA GTGTTGATGA GGCATGAAAA CATTTTGGGT
TTCATTGCTG CAGATATCAA AGGGACAGGG TCCTGGACCC AGTTGTACCT AATCACAGAC
TATCATGAAA ATGGTTCCCT TTATGATTAT CTGAAGTCCA CCACCCTAGA CGCTAAATCA
ATGCTGAAGT TAGCCTACTC TTCTGTCAGT GGCTTATGTC ATTTACACAC AGAAATCTTT
AGTACTCAAG GCAAACCAGC AATTGCCCAT CGAGATCTGA AAAGTAAAAA CATTCTGGTG
AAGAAAAATG GAACTTGCTG TATTGCTGAC CTGGGCCTGG CTGTTAAATT TATTAGTGAT
ACAAATGAAG TTGACATACC ACCTAACACT CGAGTTGGCA CCAAACGCTA TATGCCTCCA
GAAGTGTTGG ACGAGAGCTT GAACAGAAAT CACTTCCAGT CTTACATCAT GGCTGACATG
TATAGTTTTG GCCTCATCCT TTGGGAGGTT GCTAGGAGAT GTGTATCAGG AGGTATAGTG
GAAGAATACC AGCTTCCTTA TCATGACCTA GTGCCCAGTG ACCCCTCTTA TGAGGACATG
AGGGAGATTG TGTGCATCAA GAAGTTACGC CCCTCATTCC CAAACCGGTG GAGCAGTGAT
GAGTGTCTAA GGCAGATGGG AAAACTCATG ACAGAATGCT GGGCTCACAA TCCTGCATCA
AGGCTGACAG CCCTGCGGGT TAAGAAAACA CTTGCCAAAA TGTCAGAGTC CCAGGACATT
AAACTCTGA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq XP_016864047.1
CDS346..1854
Misc Feature(1)433..675
Misc Feature(2)937..1851
Misc Feature(3)958..1812
Misc Feature(4)order(973..987,997..999,1030..1032,1036..1038,1120..1122,1180..1191,1201..1203,1207..1209,1339..1341,1345..1347,1351..1356,1360..1362,1393..1395,1402..1404,1462..1473)
Misc Feature(5)order(973..993,997..999,1030..1032,1036..1038,1180..1185,1189..1191,1201..1203,1351..1356,1360..1362,1393..1395)
Misc Feature(6)order(985..987,1201..1203,1207..1209,1339..1341,1345..1347,1351..1353,1402..1404,1462..1473)
Misc Feature(7)order(1066..1071,1078..1083,1090..1092,1135..1137,1141..1143)
Misc Feature(8)1390..1473
Translation

Target ORF information:

RefSeq Version XM_017008558.1
Organism Homo sapiens(Human)
Definition Homo sapiens bone morphogenetic protein receptor type 1B (BMPR1B), transcript variant X1, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
XM_017008558.1

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
1501
ATGCTTTTGC GAAGTGCAGG AAAATTAAAT GTGGGCACCA AGAAAGAGGA TGGTGAGAGT 
ACAGCCCCCA CCCCCCGTCC AAAGGTCTTG CGTTGTAAAT GCCACCACCA TTGTCCAGAA
GACTCAGTCA ACAATATTTG CAGCACAGAC GGATATTGTT TCACGATGAT AGAAGAGGAT
GACTCTGGGT TGCCTGTGGT CACTTCTGGT TGCCTAGGAC TAGAAGGCTC AGATTTTCAG
TGTCGGGACA CTCCCATTCC TCATCAAAGA AGATCAATTG AATGCTGCAC AGAAAGGAAC
GAATGTAATA AAGACCTACA CCCTACACTG CCTCCATTGA AAAACAGAGA TTTTGTTGAT
GGACCTATAC ACCACAGGGC TTTACTTATA TCTGTGACTG TCTGTAGTTT GCTCTTGGTC
CTTATCATAT TATTTTGTTA CTTCCGGTAT AAAAGACAAG AAACCAGACC TCGATACAGC
ATTGGGTTAG AACAGGATGA AACTTACATT CCTCCTGGAG AATCCCTGAG AGACTTAATT
GAGCAGTCTC AGAGCTCAGG AAGTGGATCA GGCCTCCCTC TGCTGGTCCA AAGGACTATA
GCTAAGCAGA TTCAGATGGT GAAACAGATT GGAAAAGGTC GCTATGGGGA AGTTTGGATG
GGAAAGTGGC GTGGCGAAAA GGTAGCTGTG AAAGTGTTCT TCACCACAGA GGAAGCCAGC
TGGTTCAGAG AGACAGAAAT ATATCAGACA GTGTTGATGA GGCATGAAAA CATTTTGGGT
TTCATTGCTG CAGATATCAA AGGGACAGGG TCCTGGACCC AGTTGTACCT AATCACAGAC
TATCATGAAA ATGGTTCCCT TTATGATTAT CTGAAGTCCA CCACCCTAGA CGCTAAATCA
ATGCTGAAGT TAGCCTACTC TTCTGTCAGT GGCTTATGTC ATTTACACAC AGAAATCTTT
AGTACTCAAG GCAAACCAGC AATTGCCCAT CGAGATCTGA AAAGTAAAAA CATTCTGGTG
AAGAAAAATG GAACTTGCTG TATTGCTGAC CTGGGCCTGG CTGTTAAATT TATTAGTGAT
ACAAATGAAG TTGACATACC ACCTAACACT CGAGTTGGCA CCAAACGCTA TATGCCTCCA
GAAGTGTTGG ACGAGAGCTT GAACAGAAAT CACTTCCAGT CTTACATCAT GGCTGACATG
TATAGTTTTG GCCTCATCCT TTGGGAGGTT GCTAGGAGAT GTGTATCAGG AGGTATAGTG
GAAGAATACC AGCTTCCTTA TCATGACCTA GTGCCCAGTG ACCCCTCTTA TGAGGACATG
AGGGAGATTG TGTGCATCAA GAAGTTACGC CCCTCATTCC CAAACCGGTG GAGCAGTGAT
GAGTGTCTAA GGCAGATGGG AAAACTCATG ACAGAATGCT GGGCTCACAA TCCTGCATCA
AGGCTGACAG CCCTGCGGGT TAAGAAAACA CTTGCCAAAA TGTCAGAGTC CCAGGACATT
AAACTCTGA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OHu11503
Clone ID Related Accession (Same CDS sequence) XM_011532201.2 , NM_001256794.1 , XM_011532201.1 , XM_017008558.1 , XM_017008559.1 , XM_017008560.1 , XM_017008561.1 , NM_001203.2 , XM_011532202.1 , NM_001256792.1
Accession Version XM_017008559.1 Latest version! Documents for ORF clone product in dufault vector
Sequence Information ORF Nucleotide Sequence (Length: 1509bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags COA
ORF Insert Method CloneEZ® Seamless cloning technology
Insert Structure linear
Update Date 2016-06-06
Organism Homo sapiens(Human)
Product bone morphogenetic protein receptor type-1B isoform X1
Comment MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000004.12) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Homo sapiens Annotation Release 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
1501
ATGCTTTTGC GAAGTGCAGG AAAATTAAAT GTGGGCACCA AGAAAGAGGA TGGTGAGAGT 
ACAGCCCCCA CCCCCCGTCC AAAGGTCTTG CGTTGTAAAT GCCACCACCA TTGTCCAGAA
GACTCAGTCA ACAATATTTG CAGCACAGAC GGATATTGTT TCACGATGAT AGAAGAGGAT
GACTCTGGGT TGCCTGTGGT CACTTCTGGT TGCCTAGGAC TAGAAGGCTC AGATTTTCAG
TGTCGGGACA CTCCCATTCC TCATCAAAGA AGATCAATTG AATGCTGCAC AGAAAGGAAC
GAATGTAATA AAGACCTACA CCCTACACTG CCTCCATTGA AAAACAGAGA TTTTGTTGAT
GGACCTATAC ACCACAGGGC TTTACTTATA TCTGTGACTG TCTGTAGTTT GCTCTTGGTC
CTTATCATAT TATTTTGTTA CTTCCGGTAT AAAAGACAAG AAACCAGACC TCGATACAGC
ATTGGGTTAG AACAGGATGA AACTTACATT CCTCCTGGAG AATCCCTGAG AGACTTAATT
GAGCAGTCTC AGAGCTCAGG AAGTGGATCA GGCCTCCCTC TGCTGGTCCA AAGGACTATA
GCTAAGCAGA TTCAGATGGT GAAACAGATT GGAAAAGGTC GCTATGGGGA AGTTTGGATG
GGAAAGTGGC GTGGCGAAAA GGTAGCTGTG AAAGTGTTCT TCACCACAGA GGAAGCCAGC
TGGTTCAGAG AGACAGAAAT ATATCAGACA GTGTTGATGA GGCATGAAAA CATTTTGGGT
TTCATTGCTG CAGATATCAA AGGGACAGGG TCCTGGACCC AGTTGTACCT AATCACAGAC
TATCATGAAA ATGGTTCCCT TTATGATTAT CTGAAGTCCA CCACCCTAGA CGCTAAATCA
ATGCTGAAGT TAGCCTACTC TTCTGTCAGT GGCTTATGTC ATTTACACAC AGAAATCTTT
AGTACTCAAG GCAAACCAGC AATTGCCCAT CGAGATCTGA AAAGTAAAAA CATTCTGGTG
AAGAAAAATG GAACTTGCTG TATTGCTGAC CTGGGCCTGG CTGTTAAATT TATTAGTGAT
ACAAATGAAG TTGACATACC ACCTAACACT CGAGTTGGCA CCAAACGCTA TATGCCTCCA
GAAGTGTTGG ACGAGAGCTT GAACAGAAAT CACTTCCAGT CTTACATCAT GGCTGACATG
TATAGTTTTG GCCTCATCCT TTGGGAGGTT GCTAGGAGAT GTGTATCAGG AGGTATAGTG
GAAGAATACC AGCTTCCTTA TCATGACCTA GTGCCCAGTG ACCCCTCTTA TGAGGACATG
AGGGAGATTG TGTGCATCAA GAAGTTACGC CCCTCATTCC CAAACCGGTG GAGCAGTGAT
GAGTGTCTAA GGCAGATGGG AAAACTCATG ACAGAATGCT GGGCTCACAA TCCTGCATCA
AGGCTGACAG CCCTGCGGGT TAAGAAAACA CTTGCCAAAA TGTCAGAGTC CCAGGACATT
AAACTCTGA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq XP_016864048.1
CDS336..1844
Misc Feature(1)423..665
Misc Feature(2)927..1841
Misc Feature(3)948..1802
Misc Feature(4)order(963..977,987..989,1020..1022,1026..1028,1110..1112,1170..1181,1191..1193,1197..1199,1329..1331,1335..1337,1341..1346,1350..1352,1383..1385,1392..1394,1452..1463)
Misc Feature(5)order(963..983,987..989,1020..1022,1026..1028,1170..1175,1179..1181,1191..1193,1341..1346,1350..1352,1383..1385)
Misc Feature(6)order(975..977,1191..1193,1197..1199,1329..1331,1335..1337,1341..1343,1392..1394,1452..1463)
Misc Feature(7)order(1056..1061,1068..1073,1080..1082,1125..1127,1131..1133)
Misc Feature(8)1380..1463
Translation

Target ORF information:

RefSeq Version XM_017008559.1
Organism Homo sapiens(Human)
Definition Homo sapiens bone morphogenetic protein receptor type 1B (BMPR1B), transcript variant X2, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
XM_017008559.1

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
1501
ATGCTTTTGC GAAGTGCAGG AAAATTAAAT GTGGGCACCA AGAAAGAGGA TGGTGAGAGT 
ACAGCCCCCA CCCCCCGTCC AAAGGTCTTG CGTTGTAAAT GCCACCACCA TTGTCCAGAA
GACTCAGTCA ACAATATTTG CAGCACAGAC GGATATTGTT TCACGATGAT AGAAGAGGAT
GACTCTGGGT TGCCTGTGGT CACTTCTGGT TGCCTAGGAC TAGAAGGCTC AGATTTTCAG
TGTCGGGACA CTCCCATTCC TCATCAAAGA AGATCAATTG AATGCTGCAC AGAAAGGAAC
GAATGTAATA AAGACCTACA CCCTACACTG CCTCCATTGA AAAACAGAGA TTTTGTTGAT
GGACCTATAC ACCACAGGGC TTTACTTATA TCTGTGACTG TCTGTAGTTT GCTCTTGGTC
CTTATCATAT TATTTTGTTA CTTCCGGTAT AAAAGACAAG AAACCAGACC TCGATACAGC
ATTGGGTTAG AACAGGATGA AACTTACATT CCTCCTGGAG AATCCCTGAG AGACTTAATT
GAGCAGTCTC AGAGCTCAGG AAGTGGATCA GGCCTCCCTC TGCTGGTCCA AAGGACTATA
GCTAAGCAGA TTCAGATGGT GAAACAGATT GGAAAAGGTC GCTATGGGGA AGTTTGGATG
GGAAAGTGGC GTGGCGAAAA GGTAGCTGTG AAAGTGTTCT TCACCACAGA GGAAGCCAGC
TGGTTCAGAG AGACAGAAAT ATATCAGACA GTGTTGATGA GGCATGAAAA CATTTTGGGT
TTCATTGCTG CAGATATCAA AGGGACAGGG TCCTGGACCC AGTTGTACCT AATCACAGAC
TATCATGAAA ATGGTTCCCT TTATGATTAT CTGAAGTCCA CCACCCTAGA CGCTAAATCA
ATGCTGAAGT TAGCCTACTC TTCTGTCAGT GGCTTATGTC ATTTACACAC AGAAATCTTT
AGTACTCAAG GCAAACCAGC AATTGCCCAT CGAGATCTGA AAAGTAAAAA CATTCTGGTG
AAGAAAAATG GAACTTGCTG TATTGCTGAC CTGGGCCTGG CTGTTAAATT TATTAGTGAT
ACAAATGAAG TTGACATACC ACCTAACACT CGAGTTGGCA CCAAACGCTA TATGCCTCCA
GAAGTGTTGG ACGAGAGCTT GAACAGAAAT CACTTCCAGT CTTACATCAT GGCTGACATG
TATAGTTTTG GCCTCATCCT TTGGGAGGTT GCTAGGAGAT GTGTATCAGG AGGTATAGTG
GAAGAATACC AGCTTCCTTA TCATGACCTA GTGCCCAGTG ACCCCTCTTA TGAGGACATG
AGGGAGATTG TGTGCATCAA GAAGTTACGC CCCTCATTCC CAAACCGGTG GAGCAGTGAT
GAGTGTCTAA GGCAGATGGG AAAACTCATG ACAGAATGCT GGGCTCACAA TCCTGCATCA
AGGCTGACAG CCCTGCGGGT TAAGAAAACA CTTGCCAAAA TGTCAGAGTC CCAGGACATT
AAACTCTGA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OHu11503
Clone ID Related Accession (Same CDS sequence) XM_011532201.2 , NM_001256794.1 , XM_011532201.1 , XM_017008558.1 , XM_017008559.1 , XM_017008560.1 , XM_017008561.1 , NM_001203.2 , XM_011532202.1 , NM_001256792.1
Accession Version XM_017008560.1 Latest version! Documents for ORF clone product in dufault vector
Sequence Information ORF Nucleotide Sequence (Length: 1509bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags COA
ORF Insert Method CloneEZ® Seamless cloning technology
Insert Structure linear
Update Date 2016-06-06
Organism Homo sapiens(Human)
Product bone morphogenetic protein receptor type-1B isoform X1
Comment MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000004.12) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Homo sapiens Annotation Release 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
1501
ATGCTTTTGC GAAGTGCAGG AAAATTAAAT GTGGGCACCA AGAAAGAGGA TGGTGAGAGT 
ACAGCCCCCA CCCCCCGTCC AAAGGTCTTG CGTTGTAAAT GCCACCACCA TTGTCCAGAA
GACTCAGTCA ACAATATTTG CAGCACAGAC GGATATTGTT TCACGATGAT AGAAGAGGAT
GACTCTGGGT TGCCTGTGGT CACTTCTGGT TGCCTAGGAC TAGAAGGCTC AGATTTTCAG
TGTCGGGACA CTCCCATTCC TCATCAAAGA AGATCAATTG AATGCTGCAC AGAAAGGAAC
GAATGTAATA AAGACCTACA CCCTACACTG CCTCCATTGA AAAACAGAGA TTTTGTTGAT
GGACCTATAC ACCACAGGGC TTTACTTATA TCTGTGACTG TCTGTAGTTT GCTCTTGGTC
CTTATCATAT TATTTTGTTA CTTCCGGTAT AAAAGACAAG AAACCAGACC TCGATACAGC
ATTGGGTTAG AACAGGATGA AACTTACATT CCTCCTGGAG AATCCCTGAG AGACTTAATT
GAGCAGTCTC AGAGCTCAGG AAGTGGATCA GGCCTCCCTC TGCTGGTCCA AAGGACTATA
GCTAAGCAGA TTCAGATGGT GAAACAGATT GGAAAAGGTC GCTATGGGGA AGTTTGGATG
GGAAAGTGGC GTGGCGAAAA GGTAGCTGTG AAAGTGTTCT TCACCACAGA GGAAGCCAGC
TGGTTCAGAG AGACAGAAAT ATATCAGACA GTGTTGATGA GGCATGAAAA CATTTTGGGT
TTCATTGCTG CAGATATCAA AGGGACAGGG TCCTGGACCC AGTTGTACCT AATCACAGAC
TATCATGAAA ATGGTTCCCT TTATGATTAT CTGAAGTCCA CCACCCTAGA CGCTAAATCA
ATGCTGAAGT TAGCCTACTC TTCTGTCAGT GGCTTATGTC ATTTACACAC AGAAATCTTT
AGTACTCAAG GCAAACCAGC AATTGCCCAT CGAGATCTGA AAAGTAAAAA CATTCTGGTG
AAGAAAAATG GAACTTGCTG TATTGCTGAC CTGGGCCTGG CTGTTAAATT TATTAGTGAT
ACAAATGAAG TTGACATACC ACCTAACACT CGAGTTGGCA CCAAACGCTA TATGCCTCCA
GAAGTGTTGG ACGAGAGCTT GAACAGAAAT CACTTCCAGT CTTACATCAT GGCTGACATG
TATAGTTTTG GCCTCATCCT TTGGGAGGTT GCTAGGAGAT GTGTATCAGG AGGTATAGTG
GAAGAATACC AGCTTCCTTA TCATGACCTA GTGCCCAGTG ACCCCTCTTA TGAGGACATG
AGGGAGATTG TGTGCATCAA GAAGTTACGC CCCTCATTCC CAAACCGGTG GAGCAGTGAT
GAGTGTCTAA GGCAGATGGG AAAACTCATG ACAGAATGCT GGGCTCACAA TCCTGCATCA
AGGCTGACAG CCCTGCGGGT TAAGAAAACA CTTGCCAAAA TGTCAGAGTC CCAGGACATT
AAACTCTGA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq XP_016864049.1
CDS228..1736
Misc Feature(1)315..557
Misc Feature(2)819..1733
Misc Feature(3)840..1694
Misc Feature(4)order(855..869,879..881,912..914,918..920,1002..1004,1062..1073,1083..1085,1089..1091,1221..1223,1227..1229,1233..1238,1242..1244,1275..1277,1284..1286,1344..1355)
Misc Feature(5)order(855..875,879..881,912..914,918..920,1062..1067,1071..1073,1083..1085,1233..1238,1242..1244,1275..1277)
Misc Feature(6)order(867..869,1083..1085,1089..1091,1221..1223,1227..1229,1233..1235,1284..1286,1344..1355)
Misc Feature(7)order(948..953,960..965,972..974,1017..1019,1023..1025)
Misc Feature(8)1272..1355
Translation

Target ORF information:

RefSeq Version XM_017008560.1
Organism Homo sapiens(Human)
Definition Homo sapiens bone morphogenetic protein receptor type 1B (BMPR1B), transcript variant X3, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
XM_017008560.1

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
1501
ATGCTTTTGC GAAGTGCAGG AAAATTAAAT GTGGGCACCA AGAAAGAGGA TGGTGAGAGT 
ACAGCCCCCA CCCCCCGTCC AAAGGTCTTG CGTTGTAAAT GCCACCACCA TTGTCCAGAA
GACTCAGTCA ACAATATTTG CAGCACAGAC GGATATTGTT TCACGATGAT AGAAGAGGAT
GACTCTGGGT TGCCTGTGGT CACTTCTGGT TGCCTAGGAC TAGAAGGCTC AGATTTTCAG
TGTCGGGACA CTCCCATTCC TCATCAAAGA AGATCAATTG AATGCTGCAC AGAAAGGAAC
GAATGTAATA AAGACCTACA CCCTACACTG CCTCCATTGA AAAACAGAGA TTTTGTTGAT
GGACCTATAC ACCACAGGGC TTTACTTATA TCTGTGACTG TCTGTAGTTT GCTCTTGGTC
CTTATCATAT TATTTTGTTA CTTCCGGTAT AAAAGACAAG AAACCAGACC TCGATACAGC
ATTGGGTTAG AACAGGATGA AACTTACATT CCTCCTGGAG AATCCCTGAG AGACTTAATT
GAGCAGTCTC AGAGCTCAGG AAGTGGATCA GGCCTCCCTC TGCTGGTCCA AAGGACTATA
GCTAAGCAGA TTCAGATGGT GAAACAGATT GGAAAAGGTC GCTATGGGGA AGTTTGGATG
GGAAAGTGGC GTGGCGAAAA GGTAGCTGTG AAAGTGTTCT TCACCACAGA GGAAGCCAGC
TGGTTCAGAG AGACAGAAAT ATATCAGACA GTGTTGATGA GGCATGAAAA CATTTTGGGT
TTCATTGCTG CAGATATCAA AGGGACAGGG TCCTGGACCC AGTTGTACCT AATCACAGAC
TATCATGAAA ATGGTTCCCT TTATGATTAT CTGAAGTCCA CCACCCTAGA CGCTAAATCA
ATGCTGAAGT TAGCCTACTC TTCTGTCAGT GGCTTATGTC ATTTACACAC AGAAATCTTT
AGTACTCAAG GCAAACCAGC AATTGCCCAT CGAGATCTGA AAAGTAAAAA CATTCTGGTG
AAGAAAAATG GAACTTGCTG TATTGCTGAC CTGGGCCTGG CTGTTAAATT TATTAGTGAT
ACAAATGAAG TTGACATACC ACCTAACACT CGAGTTGGCA CCAAACGCTA TATGCCTCCA
GAAGTGTTGG ACGAGAGCTT GAACAGAAAT CACTTCCAGT CTTACATCAT GGCTGACATG
TATAGTTTTG GCCTCATCCT TTGGGAGGTT GCTAGGAGAT GTGTATCAGG AGGTATAGTG
GAAGAATACC AGCTTCCTTA TCATGACCTA GTGCCCAGTG ACCCCTCTTA TGAGGACATG
AGGGAGATTG TGTGCATCAA GAAGTTACGC CCCTCATTCC CAAACCGGTG GAGCAGTGAT
GAGTGTCTAA GGCAGATGGG AAAACTCATG ACAGAATGCT GGGCTCACAA TCCTGCATCA
AGGCTGACAG CCCTGCGGGT TAAGAAAACA CTTGCCAAAA TGTCAGAGTC CCAGGACATT
AAACTCTGA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OHu11503
Clone ID Related Accession (Same CDS sequence) XM_011532201.2 , NM_001256794.1 , XM_011532201.1 , XM_017008558.1 , XM_017008559.1 , XM_017008560.1 , XM_017008561.1 , NM_001203.2 , XM_011532202.1 , NM_001256792.1
Accession Version XM_017008561.1 Latest version! Documents for ORF clone product in dufault vector
Sequence Information ORF Nucleotide Sequence (Length: 1509bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags COA
ORF Insert Method CloneEZ® Seamless cloning technology
Insert Structure linear
Update Date 2016-06-06
Organism Homo sapiens(Human)
Product bone morphogenetic protein receptor type-1B isoform X1
Comment MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000004.12) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Homo sapiens Annotation Release 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
1501
ATGCTTTTGC GAAGTGCAGG AAAATTAAAT GTGGGCACCA AGAAAGAGGA TGGTGAGAGT 
ACAGCCCCCA CCCCCCGTCC AAAGGTCTTG CGTTGTAAAT GCCACCACCA TTGTCCAGAA
GACTCAGTCA ACAATATTTG CAGCACAGAC GGATATTGTT TCACGATGAT AGAAGAGGAT
GACTCTGGGT TGCCTGTGGT CACTTCTGGT TGCCTAGGAC TAGAAGGCTC AGATTTTCAG
TGTCGGGACA CTCCCATTCC TCATCAAAGA AGATCAATTG AATGCTGCAC AGAAAGGAAC
GAATGTAATA AAGACCTACA CCCTACACTG CCTCCATTGA AAAACAGAGA TTTTGTTGAT
GGACCTATAC ACCACAGGGC TTTACTTATA TCTGTGACTG TCTGTAGTTT GCTCTTGGTC
CTTATCATAT TATTTTGTTA CTTCCGGTAT AAAAGACAAG AAACCAGACC TCGATACAGC
ATTGGGTTAG AACAGGATGA AACTTACATT CCTCCTGGAG AATCCCTGAG AGACTTAATT
GAGCAGTCTC AGAGCTCAGG AAGTGGATCA GGCCTCCCTC TGCTGGTCCA AAGGACTATA
GCTAAGCAGA TTCAGATGGT GAAACAGATT GGAAAAGGTC GCTATGGGGA AGTTTGGATG
GGAAAGTGGC GTGGCGAAAA GGTAGCTGTG AAAGTGTTCT TCACCACAGA GGAAGCCAGC
TGGTTCAGAG AGACAGAAAT ATATCAGACA GTGTTGATGA GGCATGAAAA CATTTTGGGT
TTCATTGCTG CAGATATCAA AGGGACAGGG TCCTGGACCC AGTTGTACCT AATCACAGAC
TATCATGAAA ATGGTTCCCT TTATGATTAT CTGAAGTCCA CCACCCTAGA CGCTAAATCA
ATGCTGAAGT TAGCCTACTC TTCTGTCAGT GGCTTATGTC ATTTACACAC AGAAATCTTT
AGTACTCAAG GCAAACCAGC AATTGCCCAT CGAGATCTGA AAAGTAAAAA CATTCTGGTG
AAGAAAAATG GAACTTGCTG TATTGCTGAC CTGGGCCTGG CTGTTAAATT TATTAGTGAT
ACAAATGAAG TTGACATACC ACCTAACACT CGAGTTGGCA CCAAACGCTA TATGCCTCCA
GAAGTGTTGG ACGAGAGCTT GAACAGAAAT CACTTCCAGT CTTACATCAT GGCTGACATG
TATAGTTTTG GCCTCATCCT TTGGGAGGTT GCTAGGAGAT GTGTATCAGG AGGTATAGTG
GAAGAATACC AGCTTCCTTA TCATGACCTA GTGCCCAGTG ACCCCTCTTA TGAGGACATG
AGGGAGATTG TGTGCATCAA GAAGTTACGC CCCTCATTCC CAAACCGGTG GAGCAGTGAT
GAGTGTCTAA GGCAGATGGG AAAACTCATG ACAGAATGCT GGGCTCACAA TCCTGCATCA
AGGCTGACAG CCCTGCGGGT TAAGAAAACA CTTGCCAAAA TGTCAGAGTC CCAGGACATT
AAACTCTGA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq XP_016864050.1
CDS185..1693
Misc Feature(1)272..514
Misc Feature(2)776..1690
Misc Feature(3)797..1651
Misc Feature(4)order(812..826,836..838,869..871,875..877,959..961,1019..1030,1040..1042,1046..1048,1178..1180,1184..1186,1190..1195,1199..1201,1232..1234,1241..1243,1301..1312)
Misc Feature(5)order(812..832,836..838,869..871,875..877,1019..1024,1028..1030,1040..1042,1190..1195,1199..1201,1232..1234)
Misc Feature(6)order(824..826,1040..1042,1046..1048,1178..1180,1184..1186,1190..1192,1241..1243,1301..1312)
Misc Feature(7)order(905..910,917..922,929..931,974..976,980..982)
Misc Feature(8)1229..1312
Translation

Target ORF information:

RefSeq Version XM_017008561.1
Organism Homo sapiens(Human)
Definition Homo sapiens bone morphogenetic protein receptor type 1B (BMPR1B), transcript variant X4, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
XM_017008561.1

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
1501
ATGCTTTTGC GAAGTGCAGG AAAATTAAAT GTGGGCACCA AGAAAGAGGA TGGTGAGAGT 
ACAGCCCCCA CCCCCCGTCC AAAGGTCTTG CGTTGTAAAT GCCACCACCA TTGTCCAGAA
GACTCAGTCA ACAATATTTG CAGCACAGAC GGATATTGTT TCACGATGAT AGAAGAGGAT
GACTCTGGGT TGCCTGTGGT CACTTCTGGT TGCCTAGGAC TAGAAGGCTC AGATTTTCAG
TGTCGGGACA CTCCCATTCC TCATCAAAGA AGATCAATTG AATGCTGCAC AGAAAGGAAC
GAATGTAATA AAGACCTACA CCCTACACTG CCTCCATTGA AAAACAGAGA TTTTGTTGAT
GGACCTATAC ACCACAGGGC TTTACTTATA TCTGTGACTG TCTGTAGTTT GCTCTTGGTC
CTTATCATAT TATTTTGTTA CTTCCGGTAT AAAAGACAAG AAACCAGACC TCGATACAGC
ATTGGGTTAG AACAGGATGA AACTTACATT CCTCCTGGAG AATCCCTGAG AGACTTAATT
GAGCAGTCTC AGAGCTCAGG AAGTGGATCA GGCCTCCCTC TGCTGGTCCA AAGGACTATA
GCTAAGCAGA TTCAGATGGT GAAACAGATT GGAAAAGGTC GCTATGGGGA AGTTTGGATG
GGAAAGTGGC GTGGCGAAAA GGTAGCTGTG AAAGTGTTCT TCACCACAGA GGAAGCCAGC
TGGTTCAGAG AGACAGAAAT ATATCAGACA GTGTTGATGA GGCATGAAAA CATTTTGGGT
TTCATTGCTG CAGATATCAA AGGGACAGGG TCCTGGACCC AGTTGTACCT AATCACAGAC
TATCATGAAA ATGGTTCCCT TTATGATTAT CTGAAGTCCA CCACCCTAGA CGCTAAATCA
ATGCTGAAGT TAGCCTACTC TTCTGTCAGT GGCTTATGTC ATTTACACAC AGAAATCTTT
AGTACTCAAG GCAAACCAGC AATTGCCCAT CGAGATCTGA AAAGTAAAAA CATTCTGGTG
AAGAAAAATG GAACTTGCTG TATTGCTGAC CTGGGCCTGG CTGTTAAATT TATTAGTGAT
ACAAATGAAG TTGACATACC ACCTAACACT CGAGTTGGCA CCAAACGCTA TATGCCTCCA
GAAGTGTTGG ACGAGAGCTT GAACAGAAAT CACTTCCAGT CTTACATCAT GGCTGACATG
TATAGTTTTG GCCTCATCCT TTGGGAGGTT GCTAGGAGAT GTGTATCAGG AGGTATAGTG
GAAGAATACC AGCTTCCTTA TCATGACCTA GTGCCCAGTG ACCCCTCTTA TGAGGACATG
AGGGAGATTG TGTGCATCAA GAAGTTACGC CCCTCATTCC CAAACCGGTG GAGCAGTGAT
GAGTGTCTAA GGCAGATGGG AAAACTCATG ACAGAATGCT GGGCTCACAA TCCTGCATCA
AGGCTGACAG CCCTGCGGGT TAAGAAAACA CTTGCCAAAA TGTCAGAGTC CCAGGACATT
AAACTCTGA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OHu11503
Clone ID Related Accession (Same CDS sequence) XM_011532201.2 , NM_001256794.1 , XM_011532201.1 , XM_017008558.1 , XM_017008559.1 , XM_017008560.1 , XM_017008561.1 , NM_001203.2 , XM_011532202.1 , NM_001256792.1
Accession Version XM_011532202.1 Latest version! Documents for ORF clone product in dufault vector
Sequence Information ORF Nucleotide Sequence (Length: 1509bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags COA
ORF Insert Method CloneEZ® Seamless cloning technology
Insert Structure linear
Update Date 2015-03-12
Organism Homo sapiens(Human)
Product bone morphogenetic protein receptor type-1B isoform X1
Comment

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
1501
ATGCTTTTGC GAAGTGCAGG AAAATTAAAT GTGGGCACCA AGAAAGAGGA TGGTGAGAGT 
ACAGCCCCCA CCCCCCGTCC AAAGGTCTTG CGTTGTAAAT GCCACCACCA TTGTCCAGAA
GACTCAGTCA ACAATATTTG CAGCACAGAC GGATATTGTT TCACGATGAT AGAAGAGGAT
GACTCTGGGT TGCCTGTGGT CACTTCTGGT TGCCTAGGAC TAGAAGGCTC AGATTTTCAG
TGTCGGGACA CTCCCATTCC TCATCAAAGA AGATCAATTG AATGCTGCAC AGAAAGGAAC
GAATGTAATA AAGACCTACA CCCTACACTG CCTCCATTGA AAAACAGAGA TTTTGTTGAT
GGACCTATAC ACCACAGGGC TTTACTTATA TCTGTGACTG TCTGTAGTTT GCTCTTGGTC
CTTATCATAT TATTTTGTTA CTTCCGGTAT AAAAGACAAG AAACCAGACC TCGATACAGC
ATTGGGTTAG AACAGGATGA AACTTACATT CCTCCTGGAG AATCCCTGAG AGACTTAATT
GAGCAGTCTC AGAGCTCAGG AAGTGGATCA GGCCTCCCTC TGCTGGTCCA AAGGACTATA
GCTAAGCAGA TTCAGATGGT GAAACAGATT GGAAAAGGTC GCTATGGGGA AGTTTGGATG
GGAAAGTGGC GTGGCGAAAA GGTAGCTGTG AAAGTGTTCT TCACCACAGA GGAAGCCAGC
TGGTTCAGAG AGACAGAAAT ATATCAGACA GTGTTGATGA GGCATGAAAA CATTTTGGGT
TTCATTGCTG CAGATATCAA AGGGACAGGG TCCTGGACCC AGTTGTACCT AATCACAGAC
TATCATGAAA ATGGTTCCCT TTATGATTAT CTGAAGTCCA CCACCCTAGA CGCTAAATCA
ATGCTGAAGT TAGCCTACTC TTCTGTCAGT GGCTTATGTC ATTTACACAC AGAAATCTTT
AGTACTCAAG GCAAACCAGC AATTGCCCAT CGAGATCTGA AAAGTAAAAA CATTCTGGTG
AAGAAAAATG GAACTTGCTG TATTGCTGAC CTGGGCCTGG CTGTTAAATT TATTAGTGAT
ACAAATGAAG TTGACATACC ACCTAACACT CGAGTTGGCA CCAAACGCTA TATGCCTCCA
GAAGTGTTGG ACGAGAGCTT GAACAGAAAT CACTTCCAGT CTTACATCAT GGCTGACATG
TATAGTTTTG GCCTCATCCT TTGGGAGGTT GCTAGGAGAT GTGTATCAGG AGGTATAGTG
GAAGAATACC AGCTTCCTTA TCATGACCTA GTGCCCAGTG ACCCCTCTTA TGAGGACATG
AGGGAGATTG TGTGCATCAA GAAGTTACGC CCCTCATTCC CAAACCGGTG GAGCAGTGAT
GAGTGTCTAA GGCAGATGGG AAAACTCATG ACAGAATGCT GGGCTCACAA TCCTGCATCA
AGGCTGACAG CCCTGCGGGT TAAGAAAACA CTTGCCAAAA TGTCAGAGTC CCAGGACATT
AAACTCTGA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq XP_011530504.1
Translation

Target ORF information:

RefSeq Version XM_011532202.1
Organism Homo sapiens(Human)
Definition Homo sapiens bone morphogenetic protein receptor, type IB (BMPR1B), transcript variant X2, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
XM_011532202.1

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
1501
ATGCTTTTGC GAAGTGCAGG AAAATTAAAT GTGGGCACCA AGAAAGAGGA TGGTGAGAGT 
ACAGCCCCCA CCCCCCGTCC AAAGGTCTTG CGTTGTAAAT GCCACCACCA TTGTCCAGAA
GACTCAGTCA ACAATATTTG CAGCACAGAC GGATATTGTT TCACGATGAT AGAAGAGGAT
GACTCTGGGT TGCCTGTGGT CACTTCTGGT TGCCTAGGAC TAGAAGGCTC AGATTTTCAG
TGTCGGGACA CTCCCATTCC TCATCAAAGA AGATCAATTG AATGCTGCAC AGAAAGGAAC
GAATGTAATA AAGACCTACA CCCTACACTG CCTCCATTGA AAAACAGAGA TTTTGTTGAT
GGACCTATAC ACCACAGGGC TTTACTTATA TCTGTGACTG TCTGTAGTTT GCTCTTGGTC
CTTATCATAT TATTTTGTTA CTTCCGGTAT AAAAGACAAG AAACCAGACC TCGATACAGC
ATTGGGTTAG AACAGGATGA AACTTACATT CCTCCTGGAG AATCCCTGAG AGACTTAATT
GAGCAGTCTC AGAGCTCAGG AAGTGGATCA GGCCTCCCTC TGCTGGTCCA AAGGACTATA
GCTAAGCAGA TTCAGATGGT GAAACAGATT GGAAAAGGTC GCTATGGGGA AGTTTGGATG
GGAAAGTGGC GTGGCGAAAA GGTAGCTGTG AAAGTGTTCT TCACCACAGA GGAAGCCAGC
TGGTTCAGAG AGACAGAAAT ATATCAGACA GTGTTGATGA GGCATGAAAA CATTTTGGGT
TTCATTGCTG CAGATATCAA AGGGACAGGG TCCTGGACCC AGTTGTACCT AATCACAGAC
TATCATGAAA ATGGTTCCCT TTATGATTAT CTGAAGTCCA CCACCCTAGA CGCTAAATCA
ATGCTGAAGT TAGCCTACTC TTCTGTCAGT GGCTTATGTC ATTTACACAC AGAAATCTTT
AGTACTCAAG GCAAACCAGC AATTGCCCAT CGAGATCTGA AAAGTAAAAA CATTCTGGTG
AAGAAAAATG GAACTTGCTG TATTGCTGAC CTGGGCCTGG CTGTTAAATT TATTAGTGAT
ACAAATGAAG TTGACATACC ACCTAACACT CGAGTTGGCA CCAAACGCTA TATGCCTCCA
GAAGTGTTGG ACGAGAGCTT GAACAGAAAT CACTTCCAGT CTTACATCAT GGCTGACATG
TATAGTTTTG GCCTCATCCT TTGGGAGGTT GCTAGGAGAT GTGTATCAGG AGGTATAGTG
GAAGAATACC AGCTTCCTTA TCATGACCTA GTGCCCAGTG ACCCCTCTTA TGAGGACATG
AGGGAGATTG TGTGCATCAA GAAGTTACGC CCCTCATTCC CAAACCGGTG GAGCAGTGAT
GAGTGTCTAA GGCAGATGGG AAAACTCATG ACAGAATGCT GGGCTCACAA TCCTGCATCA
AGGCTGACAG CCCTGCGGGT TAAGAAAACA CTTGCCAAAA TGTCAGAGTC CCAGGACATT
AAACTCTGA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

book

Long-Range Communication Network in the Type 1B Bone Morphogenetic Protein Receptor.
Biochemistry54(48)7079-88(2015 Dec)
Evangelista W,Yeh LC,Gmyrek A,Lee JC,Lee JC


book

Two novel disease-causing variants in BMPR1B are associated with brachydactyly type A1.
European journal of human genetics : EJHG23(12)1640-5(2015 Dec)
Racacho L,Byrnes AM,MacDonald H,Dranse HJ,Nikkel SM,Allanson J,Rosser E,Underhill TM,Bulman DE


book

Novel mutation in the BMPR1B gene (R486L) in a Polish family and further delineation of the phenotypic features of BMPR1B-related brachydactyly.
Birth defects research. Part A, Clinical and molecular teratology103(6)567-72(2015 Jun)
Badura-Stronka M,Mróz D,Beighton P,Łukawiecki S,Wicher K,Latos-Bieleńska A,Kozłowski K


book

A hypomorphic BMPR1B mutation causes du Pan acromesomelic dysplasia.
Orphanet journal of rare diseases1084(2015 Jun)
Stange K,Désir J,Kakar N,Mueller TD,Budde BS,Gordon CT,Horn D,Seemann P,Borck G


book

Disequilibrium of BMP2 levels in the breast stem cell niche launches epithelial transformation by overamplifying BMPR1B cell response.
Stem cell reports4(2)239-54(2015 Feb)
Chapellier M,Bachelard-Cascales E,Schmidt X,Clément F,Treilleux I,Delay E,Jammot A,Ménétrier-Caux C,Pochon G,Besançon R,Voeltzel T,Caron de Fromentel C,Caux C,Blay JY,Iggo R,Maguer-Satta V


 
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