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SNCA cDNA ORF clone, Homo sapiens (human)

Gene Symbol SNCA
Entrez Gene ID 6622
Full Name synuclein, alpha (non A4 component of amyloid precursor)
Synonyms NACP, PARK1, PARK4, PD1
Gene Type protein-coding
Organism Homo sapiens (human)
Genome

4

4q21

Summary Alpha-synuclein is a member of the synuclein family, which also includes beta- and gamma-synuclein. Synucleins are abundantly expressed in the brain and alpha- and beta-synuclein inhibit phospholipase D2 selectively. SNCA may serve to integrate presynaptic signaling and membrane trafficking. Defects in SNCA have been implicated in the pathogenesis of Parkinson disease. SNCA peptides are a major component of amyloid plaques in the brains of patients with Alzheimer's disease. Four alternatively spliced transcripts encoding two different isoforms have been identified for this gene. [provided by RefSeq, Mar 2009]. lac of sum
Disorder MIM:

163890

Disorder Html: Parkinson disease 4, 605543 (3); Dementia, Lewy body, 127750 (3);

mRNA and Protein(s)

mRNA Protein Name
XM_011532203 XP_011530505 alpha-synuclein isoform X2
XM_011532204 XP_011530506 alpha-synuclein isoform X2
XM_011532205 XP_011530507 alpha-synuclein isoform X2
XM_011532206 XP_011530508 alpha-synuclein isoform X2
XM_011532207 XP_011530509 alpha-synuclein isoform X2
XM_011532208 XP_011530510 alpha-synuclein isoform X1
NM_000345 NP_000336 alpha-synuclein isoform NACP140
NM_007308 NP_009292 alpha-synuclein isoform NACP112
NM_001146054 NP_001139526 alpha-synuclein isoform NACP140
NM_001146055 NP_001139527 alpha-synuclein isoform NACP140



Homo sapiens (human) SNCA NP_001139527.1
Pan troglodytes (chimpanzee) SNCA NP_001009158.1
Canis lupus familiaris (dog) SNCA XP_860942.1
Bos taurus (cattle) SNCA NP_001029213.1
Mus musculus (house mouse) Snca NP_001035916.1
Rattus norvegicus (Norway rat) Snca NP_062042.1
Gallus gallus (chicken) SNCA NP_990004.1
Xenopus (Silurana) tropicalis (western clawed frog) snca NP_001090876.1


GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following SNCA gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the SNCA cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

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***CloneID RefSeq Accession Definition **Vector *Turnaround time Price (USD) Select
OHu60654 XM_011532203 PREDICTED: Homo sapiens synuclein, alpha (non A4 component of amyloid precursor) (SNCA), transcript variant X1, mRNA. pcDNA3.1+/C-(K)DYK or customized vector 7-9 $69.30
$99.00
OHu60654 XM_011532204 PREDICTED: Homo sapiens synuclein, alpha (non A4 component of amyloid precursor) (SNCA), transcript variant X2, mRNA. pcDNA3.1+/C-(K)DYK or customized vector 7-9 $69.30
$99.00
OHu60654 XM_011532205 PREDICTED: Homo sapiens synuclein, alpha (non A4 component of amyloid precursor) (SNCA), transcript variant X3, mRNA. pcDNA3.1+/C-(K)DYK or customized vector 7-9 $69.30
$99.00
OHu60654 XM_011532206 PREDICTED: Homo sapiens synuclein, alpha (non A4 component of amyloid precursor) (SNCA), transcript variant X4, mRNA. pcDNA3.1+/C-(K)DYK or customized vector 7-9 $69.30
$99.00
OHu60654 XM_011532207 PREDICTED: Homo sapiens synuclein, alpha (non A4 component of amyloid precursor) (SNCA), transcript variant X5, mRNA. pcDNA3.1+/C-(K)DYK or customized vector 7-9 $69.30
$99.00
OHu23545
XM_011532208 PREDICTED: Homo sapiens synuclein, alpha (non A4 component of amyloid precursor) (SNCA), transcript variant X6, mRNA. pcDNA3.1+/C-(K)DYK or customized vector
in pcDNA3.1+/C-(K)DYK
$49.50-$69.30
$99.00
OHu23545
NM_000345 Homo sapiens synuclein, alpha (non A4 component of amyloid precursor) (SNCA), transcript variant 1, mRNA. pcDNA3.1+/C-(K)DYK or customized vector
in pcDNA3.1+/C-(K)DYK
$49.50-$69.30
$99.00
OHu24073
NM_007308 Homo sapiens synuclein, alpha (non A4 component of amyloid precursor) (SNCA), transcript variant 4, mRNA. pcDNA3.1+/C-(K)DYK or customized vector
in pcDNA3.1+/C-(K)DYK
$49.50-$69.30
$99.00
OHu23545
NM_001146054 Homo sapiens synuclein, alpha (non A4 component of amyloid precursor) (SNCA), transcript variant 2, mRNA. pcDNA3.1+/C-(K)DYK or customized vector
in pcDNA3.1+/C-(K)DYK
$49.50-$69.30
$99.00
OHu23545
NM_001146055 Homo sapiens synuclein, alpha (non A4 component of amyloid precursor) (SNCA), transcript variant 3, mRNA. pcDNA3.1+/C-(K)DYK or customized vector
in pcDNA3.1+/C-(K)DYK
$49.50-$69.30
$99.00

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.


CloneID OHu60654
Clone ID Related Accession (Same CDS sequence) XM_011532203 , XM_011532204 , XM_011532205 , XM_011532206 , XM_011532207
Accession Version XM_011532203.1 Documents for ORF clone product in dufault vector
Sequence Information ORF Nucleotide Sequence (Length: 513bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ® Seamless cloning technology
Insert Structure linear
Update Date 12-MAR-2015
Organism Homo sapiens (human)
Product alpha-synuclein isoform X2
Comment MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NT_016354.20) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Homo sapiens Annotation Release 107 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 6.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

1
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181
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ATGGATGTAT TCATGAAAGG ACTTTCAAAG GCCAAGGAGG GAGTTGTGGC TGCTGCTGAG 
AAAACCAAAC AGGGTGTGGC AGAAGCAGCA GGAAAGACAA AAGAGGGTGT TCTCTATGTA
GGCTCCAAAA CCAAGGAGGG AGTGGTGCAT GGTGTGGCAA CAGTGGCTGA GAAGACCAAA
GAGCAAGTGA CAAATGTTGG AGGAGCAGTG GTGACGGGTG TGACAGCAGT AGCCCAGAAG
ACAGTGGAGG GAGCAGGGAG CATTGCAGCA GCCACTGGCT TTGTCAAAAA GGACCAGTTG
GGCAAGAAGC ATCCAAAATA CAAACCATCT AAGAGGCAAG AAAATGTCGT GATGTTCCTA
GTGCAAGTTA AAAAGATTTG CTTTCCTCAA GTCGGAAAGC CCTTCTCATT TTTGAGGTTT
TTTTCTTCTT TTTTTTTTCA AGTGAAAGCA TTTTGGAGGA GTCAATATCC ATCTTTAAAG
GTAGCCAGGT CACATGTATA CATATGTAAC TAA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq XP_011530505.1
CDS293..805
Misc Feature(1)293..>598(+)
Translation

Target ORF information:

RefSeq Version XM_011532203
Organism Homo sapiens (human)
Definition PREDICTED: Homo sapiens synuclein, alpha (non A4 component of amyloid precursor) (SNCA), transcript variant X1, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
XM_011532203

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
ATGGATGTAT TCATGAAAGG ACTTTCAAAG GCCAAGGAGG GAGTTGTGGC TGCTGCTGAG 
AAAACCAAAC AGGGTGTGGC AGAAGCAGCA GGAAAGACAA AAGAGGGTGT TCTCTATGTA
GGCTCCAAAA CCAAGGAGGG AGTGGTGCAT GGTGTGGCAA CAGTGGCTGA GAAGACCAAA
GAGCAAGTGA CAAATGTTGG AGGAGCAGTG GTGACGGGTG TGACAGCAGT AGCCCAGAAG
ACAGTGGAGG GAGCAGGGAG CATTGCAGCA GCCACTGGCT TTGTCAAAAA GGACCAGTTG
GGCAAGAAGC ATCCAAAATA CAAACCATCT AAGAGGCAAG AAAATGTCGT GATGTTCCTA
GTGCAAGTTA AAAAGATTTG CTTTCCTCAA GTCGGAAAGC CCTTCTCATT TTTGAGGTTT
TTTTCTTCTT TTTTTTTTCA AGTGAAAGCA TTTTGGAGGA GTCAATATCC ATCTTTAAAG
GTAGCCAGGT CACATGTATA CATATGTAAC TAA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OHu60654
Clone ID Related Accession (Same CDS sequence) XM_011532203 , XM_011532204 , XM_011532205 , XM_011532206 , XM_011532207
Accession Version XM_011532204.1 Documents for ORF clone product in dufault vector
Sequence Information ORF Nucleotide Sequence (Length: 513bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ® Seamless cloning technology
Insert Structure linear
Update Date 12-MAR-2015
Organism Homo sapiens (human)
Product alpha-synuclein isoform X2
Comment MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NT_016354.20) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Homo sapiens Annotation Release 107 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 6.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

1
61
121
181
241
301
361
421
481
ATGGATGTAT TCATGAAAGG ACTTTCAAAG GCCAAGGAGG GAGTTGTGGC TGCTGCTGAG 
AAAACCAAAC AGGGTGTGGC AGAAGCAGCA GGAAAGACAA AAGAGGGTGT TCTCTATGTA
GGCTCCAAAA CCAAGGAGGG AGTGGTGCAT GGTGTGGCAA CAGTGGCTGA GAAGACCAAA
GAGCAAGTGA CAAATGTTGG AGGAGCAGTG GTGACGGGTG TGACAGCAGT AGCCCAGAAG
ACAGTGGAGG GAGCAGGGAG CATTGCAGCA GCCACTGGCT TTGTCAAAAA GGACCAGTTG
GGCAAGAAGC ATCCAAAATA CAAACCATCT AAGAGGCAAG AAAATGTCGT GATGTTCCTA
GTGCAAGTTA AAAAGATTTG CTTTCCTCAA GTCGGAAAGC CCTTCTCATT TTTGAGGTTT
TTTTCTTCTT TTTTTTTTCA AGTGAAAGCA TTTTGGAGGA GTCAATATCC ATCTTTAAAG
GTAGCCAGGT CACATGTATA CATATGTAAC TAA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq XP_011530506.1
CDS272..784
Misc Feature(1)272..>577(+)
Translation

Target ORF information:

RefSeq Version XM_011532204
Organism Homo sapiens (human)
Definition PREDICTED: Homo sapiens synuclein, alpha (non A4 component of amyloid precursor) (SNCA), transcript variant X2, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
XM_011532204

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
ATGGATGTAT TCATGAAAGG ACTTTCAAAG GCCAAGGAGG GAGTTGTGGC TGCTGCTGAG 
AAAACCAAAC AGGGTGTGGC AGAAGCAGCA GGAAAGACAA AAGAGGGTGT TCTCTATGTA
GGCTCCAAAA CCAAGGAGGG AGTGGTGCAT GGTGTGGCAA CAGTGGCTGA GAAGACCAAA
GAGCAAGTGA CAAATGTTGG AGGAGCAGTG GTGACGGGTG TGACAGCAGT AGCCCAGAAG
ACAGTGGAGG GAGCAGGGAG CATTGCAGCA GCCACTGGCT TTGTCAAAAA GGACCAGTTG
GGCAAGAAGC ATCCAAAATA CAAACCATCT AAGAGGCAAG AAAATGTCGT GATGTTCCTA
GTGCAAGTTA AAAAGATTTG CTTTCCTCAA GTCGGAAAGC CCTTCTCATT TTTGAGGTTT
TTTTCTTCTT TTTTTTTTCA AGTGAAAGCA TTTTGGAGGA GTCAATATCC ATCTTTAAAG
GTAGCCAGGT CACATGTATA CATATGTAAC TAA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OHu60654
Clone ID Related Accession (Same CDS sequence) XM_011532203 , XM_011532204 , XM_011532205 , XM_011532206 , XM_011532207
Accession Version XM_011532205.1 Documents for ORF clone product in dufault vector
Sequence Information ORF Nucleotide Sequence (Length: 513bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ® Seamless cloning technology
Insert Structure linear
Update Date 12-MAR-2015
Organism Homo sapiens (human)
Product alpha-synuclein isoform X2
Comment MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NT_016354.20) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Homo sapiens Annotation Release 107 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 6.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

1
61
121
181
241
301
361
421
481
ATGGATGTAT TCATGAAAGG ACTTTCAAAG GCCAAGGAGG GAGTTGTGGC TGCTGCTGAG 
AAAACCAAAC AGGGTGTGGC AGAAGCAGCA GGAAAGACAA AAGAGGGTGT TCTCTATGTA
GGCTCCAAAA CCAAGGAGGG AGTGGTGCAT GGTGTGGCAA CAGTGGCTGA GAAGACCAAA
GAGCAAGTGA CAAATGTTGG AGGAGCAGTG GTGACGGGTG TGACAGCAGT AGCCCAGAAG
ACAGTGGAGG GAGCAGGGAG CATTGCAGCA GCCACTGGCT TTGTCAAAAA GGACCAGTTG
GGCAAGAAGC ATCCAAAATA CAAACCATCT AAGAGGCAAG AAAATGTCGT GATGTTCCTA
GTGCAAGTTA AAAAGATTTG CTTTCCTCAA GTCGGAAAGC CCTTCTCATT TTTGAGGTTT
TTTTCTTCTT TTTTTTTTCA AGTGAAAGCA TTTTGGAGGA GTCAATATCC ATCTTTAAAG
GTAGCCAGGT CACATGTATA CATATGTAAC TAA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq XP_011530507.1
CDS89..601
Misc Feature(1)89..>394(+)
Translation

Target ORF information:

RefSeq Version XM_011532205
Organism Homo sapiens (human)
Definition PREDICTED: Homo sapiens synuclein, alpha (non A4 component of amyloid precursor) (SNCA), transcript variant X3, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
XM_011532205

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
ATGGATGTAT TCATGAAAGG ACTTTCAAAG GCCAAGGAGG GAGTTGTGGC TGCTGCTGAG 
AAAACCAAAC AGGGTGTGGC AGAAGCAGCA GGAAAGACAA AAGAGGGTGT TCTCTATGTA
GGCTCCAAAA CCAAGGAGGG AGTGGTGCAT GGTGTGGCAA CAGTGGCTGA GAAGACCAAA
GAGCAAGTGA CAAATGTTGG AGGAGCAGTG GTGACGGGTG TGACAGCAGT AGCCCAGAAG
ACAGTGGAGG GAGCAGGGAG CATTGCAGCA GCCACTGGCT TTGTCAAAAA GGACCAGTTG
GGCAAGAAGC ATCCAAAATA CAAACCATCT AAGAGGCAAG AAAATGTCGT GATGTTCCTA
GTGCAAGTTA AAAAGATTTG CTTTCCTCAA GTCGGAAAGC CCTTCTCATT TTTGAGGTTT
TTTTCTTCTT TTTTTTTTCA AGTGAAAGCA TTTTGGAGGA GTCAATATCC ATCTTTAAAG
GTAGCCAGGT CACATGTATA CATATGTAAC TAA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OHu60654
Clone ID Related Accession (Same CDS sequence) XM_011532203 , XM_011532204 , XM_011532205 , XM_011532206 , XM_011532207
Accession Version XM_011532206.1 Documents for ORF clone product in dufault vector
Sequence Information ORF Nucleotide Sequence (Length: 513bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ® Seamless cloning technology
Insert Structure linear
Update Date 12-MAR-2015
Organism Homo sapiens (human)
Product alpha-synuclein isoform X2
Comment MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NT_016354.20) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Homo sapiens Annotation Release 107 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 6.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

1
61
121
181
241
301
361
421
481
ATGGATGTAT TCATGAAAGG ACTTTCAAAG GCCAAGGAGG GAGTTGTGGC TGCTGCTGAG 
AAAACCAAAC AGGGTGTGGC AGAAGCAGCA GGAAAGACAA AAGAGGGTGT TCTCTATGTA
GGCTCCAAAA CCAAGGAGGG AGTGGTGCAT GGTGTGGCAA CAGTGGCTGA GAAGACCAAA
GAGCAAGTGA CAAATGTTGG AGGAGCAGTG GTGACGGGTG TGACAGCAGT AGCCCAGAAG
ACAGTGGAGG GAGCAGGGAG CATTGCAGCA GCCACTGGCT TTGTCAAAAA GGACCAGTTG
GGCAAGAAGC ATCCAAAATA CAAACCATCT AAGAGGCAAG AAAATGTCGT GATGTTCCTA
GTGCAAGTTA AAAAGATTTG CTTTCCTCAA GTCGGAAAGC CCTTCTCATT TTTGAGGTTT
TTTTCTTCTT TTTTTTTTCA AGTGAAAGCA TTTTGGAGGA GTCAATATCC ATCTTTAAAG
GTAGCCAGGT CACATGTATA CATATGTAAC TAA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq XP_011530508.1
CDS121..633
Misc Feature(1)121..>426(+)
Translation

Target ORF information:

RefSeq Version XM_011532206
Organism Homo sapiens (human)
Definition PREDICTED: Homo sapiens synuclein, alpha (non A4 component of amyloid precursor) (SNCA), transcript variant X4, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
XM_011532206

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
ATGGATGTAT TCATGAAAGG ACTTTCAAAG GCCAAGGAGG GAGTTGTGGC TGCTGCTGAG 
AAAACCAAAC AGGGTGTGGC AGAAGCAGCA GGAAAGACAA AAGAGGGTGT TCTCTATGTA
GGCTCCAAAA CCAAGGAGGG AGTGGTGCAT GGTGTGGCAA CAGTGGCTGA GAAGACCAAA
GAGCAAGTGA CAAATGTTGG AGGAGCAGTG GTGACGGGTG TGACAGCAGT AGCCCAGAAG
ACAGTGGAGG GAGCAGGGAG CATTGCAGCA GCCACTGGCT TTGTCAAAAA GGACCAGTTG
GGCAAGAAGC ATCCAAAATA CAAACCATCT AAGAGGCAAG AAAATGTCGT GATGTTCCTA
GTGCAAGTTA AAAAGATTTG CTTTCCTCAA GTCGGAAAGC CCTTCTCATT TTTGAGGTTT
TTTTCTTCTT TTTTTTTTCA AGTGAAAGCA TTTTGGAGGA GTCAATATCC ATCTTTAAAG
GTAGCCAGGT CACATGTATA CATATGTAAC TAA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OHu60654
Clone ID Related Accession (Same CDS sequence) XM_011532203 , XM_011532204 , XM_011532205 , XM_011532206 , XM_011532207
Accession Version XM_011532207.1 Documents for ORF clone product in dufault vector
Sequence Information ORF Nucleotide Sequence (Length: 513bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ® Seamless cloning technology
Insert Structure linear
Update Date 12-MAR-2015
Organism Homo sapiens (human)
Product alpha-synuclein isoform X2
Comment MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NT_016354.20) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Homo sapiens Annotation Release 107 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 6.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

1
61
121
181
241
301
361
421
481
ATGGATGTAT TCATGAAAGG ACTTTCAAAG GCCAAGGAGG GAGTTGTGGC TGCTGCTGAG 
AAAACCAAAC AGGGTGTGGC AGAAGCAGCA GGAAAGACAA AAGAGGGTGT TCTCTATGTA
GGCTCCAAAA CCAAGGAGGG AGTGGTGCAT GGTGTGGCAA CAGTGGCTGA GAAGACCAAA
GAGCAAGTGA CAAATGTTGG AGGAGCAGTG GTGACGGGTG TGACAGCAGT AGCCCAGAAG
ACAGTGGAGG GAGCAGGGAG CATTGCAGCA GCCACTGGCT TTGTCAAAAA GGACCAGTTG
GGCAAGAAGC ATCCAAAATA CAAACCATCT AAGAGGCAAG AAAATGTCGT GATGTTCCTA
GTGCAAGTTA AAAAGATTTG CTTTCCTCAA GTCGGAAAGC CCTTCTCATT TTTGAGGTTT
TTTTCTTCTT TTTTTTTTCA AGTGAAAGCA TTTTGGAGGA GTCAATATCC ATCTTTAAAG
GTAGCCAGGT CACATGTATA CATATGTAAC TAA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq XP_011530509.1
CDS108..620
Misc Feature(1)108..>413(+)
Translation

Target ORF information:

RefSeq Version XM_011532207
Organism Homo sapiens (human)
Definition PREDICTED: Homo sapiens synuclein, alpha (non A4 component of amyloid precursor) (SNCA), transcript variant X5, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
XM_011532207

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
ATGGATGTAT TCATGAAAGG ACTTTCAAAG GCCAAGGAGG GAGTTGTGGC TGCTGCTGAG 
AAAACCAAAC AGGGTGTGGC AGAAGCAGCA GGAAAGACAA AAGAGGGTGT TCTCTATGTA
GGCTCCAAAA CCAAGGAGGG AGTGGTGCAT GGTGTGGCAA CAGTGGCTGA GAAGACCAAA
GAGCAAGTGA CAAATGTTGG AGGAGCAGTG GTGACGGGTG TGACAGCAGT AGCCCAGAAG
ACAGTGGAGG GAGCAGGGAG CATTGCAGCA GCCACTGGCT TTGTCAAAAA GGACCAGTTG
GGCAAGAAGC ATCCAAAATA CAAACCATCT AAGAGGCAAG AAAATGTCGT GATGTTCCTA
GTGCAAGTTA AAAAGATTTG CTTTCCTCAA GTCGGAAAGC CCTTCTCATT TTTGAGGTTT
TTTTCTTCTT TTTTTTTTCA AGTGAAAGCA TTTTGGAGGA GTCAATATCC ATCTTTAAAG
GTAGCCAGGT CACATGTATA CATATGTAAC TAA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OHu23545
Clone ID Related Accession (Same CDS sequence) NM_000345 , NM_001146054 , NM_001146055 , XM_011532208
Accession Version XM_011532208.1 Documents for ORF clone product in dufault vector
Sequence Information ORF Nucleotide Sequence (Length: 423bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags COA
ORF Insert Method CloneEZ® Seamless cloning technology
Insert Structure linear
Update Date 12-MAR-2015
Organism Homo sapiens (human)
Product alpha-synuclein isoform X1
Comment MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NT_016354.20) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Homo sapiens Annotation Release 107 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 6.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

1
61
121
181
241
301
361
421
ATGGATGTAT TCATGAAAGG ACTTTCAAAG GCCAAGGAGG GAGTTGTGGC TGCTGCTGAG 
AAAACCAAAC AGGGTGTGGC AGAAGCAGCA GGAAAGACAA AAGAGGGTGT TCTCTATGTA
GGCTCCAAAA CCAAGGAGGG AGTGGTGCAT GGTGTGGCAA CAGTGGCTGA GAAGACCAAA
GAGCAAGTGA CAAATGTTGG AGGAGCAGTG GTGACGGGTG TGACAGCAGT AGCCCAGAAG
ACAGTGGAGG GAGCAGGGAG CATTGCAGCA GCCACTGGCT TTGTCAAAAA GGACCAGTTG
GGCAAGAATG AAGAAGGAGC CCCACAGGAA GGAATTCTGG AAGATATGCC TGTGGATCCT
GACAATGAGG CTTATGAAAT GCCTTCTGAG GAAGGGTATC AAGACTACGA ACCTGAAGCC
TAA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq XP_011530510.1
CDS121..543
Misc Feature(1)121..516(+)
Translation

Target ORF information:

RefSeq Version XM_011532208
Organism Homo sapiens (human)
Definition PREDICTED: Homo sapiens synuclein, alpha (non A4 component of amyloid precursor) (SNCA), transcript variant X6, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
XM_011532208

ORF Insert Sequence:

1
61
121
181
241
301
361
421
ATGGATGTAT TCATGAAAGG ACTTTCAAAG GCCAAGGAGG GAGTTGTGGC TGCTGCTGAG 
AAAACCAAAC AGGGTGTGGC AGAAGCAGCA GGAAAGACAA AAGAGGGTGT TCTCTATGTA
GGCTCCAAAA CCAAGGAGGG AGTGGTGCAT GGTGTGGCAA CAGTGGCTGA GAAGACCAAA
GAGCAAGTGA CAAATGTTGG AGGAGCAGTG GTGACGGGTG TGACAGCAGT AGCCCAGAAG
ACAGTGGAGG GAGCAGGGAG CATTGCAGCA GCCACTGGCT TTGTCAAAAA GGACCAGTTG
GGCAAGAATG AAGAAGGAGC CCCACAGGAA GGAATTCTGG AAGATATGCC TGTGGATCCT
GACAATGAGG CTTATGAAAT GCCTTCTGAG GAAGGGTATC AAGACTACGA ACCTGAAGCC
TAA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OHu23545
Clone ID Related Accession (Same CDS sequence) NM_000345 , NM_001146054 , NM_001146055 , XM_011532208
Accession Version NM_000345.3 Documents for ORF clone product in dufault vector
Sequence Information ORF Nucleotide Sequence (Length: 423bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags COA
ORF Insert Method CloneEZ® Seamless cloning technology
Insert Structure linear
Update Date 15-MAR-2015
Organism Homo sapiens (human)
Product alpha-synuclein isoform NACP140
Comment REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AI815523.1, BC108275.1 and AC097478.2. This sequence is a reference standard in the RefSeqGene project. On Mar 26, 2009 this sequence version replaced gi:6806896. Transcript Variant: This variant (1, also known as NACP140) is the longest transcript and encodes the longer isoform (NACP140). Variants 1, 2, and 3 all encode the same isoform. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC108275.1, L08850.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2145743, SAMEA2149004 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

1
61
121
181
241
301
361
421
ATGGATGTAT TCATGAAAGG ACTTTCAAAG GCCAAGGAGG GAGTTGTGGC TGCTGCTGAG 
AAAACCAAAC AGGGTGTGGC AGAAGCAGCA GGAAAGACAA AAGAGGGTGT TCTCTATGTA
GGCTCCAAAA CCAAGGAGGG AGTGGTGCAT GGTGTGGCAA CAGTGGCTGA GAAGACCAAA
GAGCAAGTGA CAAATGTTGG AGGAGCAGTG GTGACGGGTG TGACAGCAGT AGCCCAGAAG
ACAGTGGAGG GAGCAGGGAG CATTGCAGCA GCCACTGGCT TTGTCAAAAA GGACCAGTTG
GGCAAGAATG AAGAAGGAGC CCCACAGGAA GGAATTCTGG AAGATATGCC TGTGGATCCT
GACAATGAGG CTTATGAAAT GCCTTCTGAG GAAGGGTATC AAGACTACGA ACCTGAAGCC
TAA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq NP_000336.1
CDS264..686
Misc Feature(1)246..248(+)
Misc Feature(2)264..659(+)
Misc Feature(3)264..266(+)
Misc Feature(4)297..299(+)
Misc Feature(5)321..464(+)
Misc Feature(6)522..524(+)
Misc Feature(7)531..533(+)
Misc Feature(8)636..638(+)
Misc Feature(9)645..647(+)
Misc Feature(10)645..647(+)
Misc Feature(11)645..647(+)
Misc Feature(12)645..647(+)
Misc Feature(13)645..647(+)
Misc Feature(14)648..650(+)
Misc Feature(15)657..659(+)
Misc Feature(16)657..659(+)
Misc Feature(17)657..659(+)
Misc Feature(18)657..659(+)
Misc Feature(19)657..659(+)
Misc Feature(20)669..671(+)
Misc Feature(21)678..680(+)
Exon (1)1..238
Gene:SNCA
Gene Synonym:
Exon (2)239..384
Gene:SNCA
Gene Synonym:
Exon (3)385..426
Gene:SNCA
Gene Synonym:
Exon (4)427..569
Gene:SNCA
Gene Synonym:
Exon (5)570..653
Gene:SNCA
Gene Synonym:
Exon (6)654..3215
Gene:SNCA
Gene Synonym:
Translation

Target ORF information:

RefSeq Version NM_000345
Organism Homo sapiens (human)
Definition Homo sapiens synuclein, alpha (non A4 component of amyloid precursor) (SNCA), transcript variant 1, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
NM_000345

ORF Insert Sequence:

1
61
121
181
241
301
361
421
ATGGATGTAT TCATGAAAGG ACTTTCAAAG GCCAAGGAGG GAGTTGTGGC TGCTGCTGAG 
AAAACCAAAC AGGGTGTGGC AGAAGCAGCA GGAAAGACAA AAGAGGGTGT TCTCTATGTA
GGCTCCAAAA CCAAGGAGGG AGTGGTGCAT GGTGTGGCAA CAGTGGCTGA GAAGACCAAA
GAGCAAGTGA CAAATGTTGG AGGAGCAGTG GTGACGGGTG TGACAGCAGT AGCCCAGAAG
ACAGTGGAGG GAGCAGGGAG CATTGCAGCA GCCACTGGCT TTGTCAAAAA GGACCAGTTG
GGCAAGAATG AAGAAGGAGC CCCACAGGAA GGAATTCTGG AAGATATGCC TGTGGATCCT
GACAATGAGG CTTATGAAAT GCCTTCTGAG GAAGGGTATC AAGACTACGA ACCTGAAGCC
TAA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OHu24073
Clone ID Related Accession (Same CDS sequence) NM_007308
Accession Version NM_007308.2 Documents for ORF clone product in dufault vector
Sequence Information ORF Nucleotide Sequence (Length: 339bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags COA
ORF Insert Method CloneEZ® Seamless cloning technology
Insert Structure linear
Update Date 15-MAR-2015
Organism Homo sapiens (human)
Product alpha-synuclein isoform NACP112
Comment REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AC093759.3, D31839.1 and AC097478.2. On Mar 26, 2009 this sequence version replaced gi:6806897. Transcript Variant: This variant (4, also known as NACP112) lacks an alternate in-frame exon compared to variant 1. The resulting isoform (NACP112) has the same N- and C-termini but is shorter compared to isoform NACP140. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BG714648.1, BI667295.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

1
61
121
181
241
301
ATGGATGTAT TCATGAAAGG ACTTTCAAAG GCCAAGGAGG GAGTTGTGGC TGCTGCTGAG 
AAAACCAAAC AGGGTGTGGC AGAAGCAGCA GGAAAGACAA AAGAGGGTGT TCTCTATGTA
GGCTCCAAAA CCAAGGAGGG AGTGGTGCAT GGTGTGGCAA CAGTGGCTGA GAAGACCAAA
GAGCAAGTGA CAAATGTTGG AGGAGCAGTG GTGACGGGTG TGACAGCAGT AGCCCAGAAG
ACAGTGGAGG GAGCAGGGAG CATTGCAGCA GCCACTGGCT TTGTCAAAAA GGACCAGTTG
GGCAAGGAAG GGTATCAAGA CTACGAACCT GAAGCCTAA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq NP_009292.1
CDS260..598
Misc Feature(1)242..244(+)
Misc Feature(2)260..>568(+)
Misc Feature(3)518..520(+)
Misc Feature(4)581..583(+)
Exon (1)1..234
Gene:SNCA
Gene Synonym:
Exon (2)235..380
Gene:SNCA
Gene Synonym:
Exon (3)381..422
Gene:SNCA
Gene Synonym:
Exon (4)423..565
Gene:SNCA
Gene Synonym:
Exon (5)566..3127
Gene:SNCA
Gene Synonym:
Translation

Target ORF information:

RefSeq Version NM_007308
Organism Homo sapiens (human)
Definition Homo sapiens synuclein, alpha (non A4 component of amyloid precursor) (SNCA), transcript variant 4, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
NM_007308

ORF Insert Sequence:

1
61
121
181
241
301
ATGGATGTAT TCATGAAAGG ACTTTCAAAG GCCAAGGAGG GAGTTGTGGC TGCTGCTGAG 
AAAACCAAAC AGGGTGTGGC AGAAGCAGCA GGAAAGACAA AAGAGGGTGT TCTCTATGTA
GGCTCCAAAA CCAAGGAGGG AGTGGTGCAT GGTGTGGCAA CAGTGGCTGA GAAGACCAAA
GAGCAAGTGA CAAATGTTGG AGGAGCAGTG GTGACGGGTG TGACAGCAGT AGCCCAGAAG
ACAGTGGAGG GAGCAGGGAG CATTGCAGCA GCCACTGGCT TTGTCAAAAA GGACCAGTTG
GGCAAGGAAG GGTATCAAGA CTACGAACCT GAAGCCTAA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OHu23545
Clone ID Related Accession (Same CDS sequence) NM_000345 , NM_001146054 , NM_001146055 , XM_011532208
Accession Version NM_001146054.1 Documents for ORF clone product in dufault vector
Sequence Information ORF Nucleotide Sequence (Length: 423bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags COA
ORF Insert Method CloneEZ® Seamless cloning technology
Insert Structure linear
Update Date 15-MAR-2015
Organism Homo sapiens (human)
Product alpha-synuclein isoform NACP140
Comment REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AC093759.3, BC013293.2 and AC097478.2. Transcript Variant: This variant (2) differs in the 5' UTR compared to variant 1. Variants 1, 2, and 3 all encode the same isoform (NACP140). Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC013293.2, BQ231431.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

1
61
121
181
241
301
361
421
ATGGATGTAT TCATGAAAGG ACTTTCAAAG GCCAAGGAGG GAGTTGTGGC TGCTGCTGAG 
AAAACCAAAC AGGGTGTGGC AGAAGCAGCA GGAAAGACAA AAGAGGGTGT TCTCTATGTA
GGCTCCAAAA CCAAGGAGGG AGTGGTGCAT GGTGTGGCAA CAGTGGCTGA GAAGACCAAA
GAGCAAGTGA CAAATGTTGG AGGAGCAGTG GTGACGGGTG TGACAGCAGT AGCCCAGAAG
ACAGTGGAGG GAGCAGGGAG CATTGCAGCA GCCACTGGCT TTGTCAAAAA GGACCAGTTG
GGCAAGAATG AAGAAGGAGC CCCACAGGAA GGAATTCTGG AAGATATGCC TGTGGATCCT
GACAATGAGG CTTATGAAAT GCCTTCTGAG GAAGGGTATC AAGACTACGA ACCTGAAGCC
TAA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq NP_001139526.1
CDS260..682
Misc Feature(1)242..244(+)
Misc Feature(2)260..655(+)
Misc Feature(3)260..262(+)
Misc Feature(4)317..460(+)
Misc Feature(5)518..520(+)
Misc Feature(6)632..634(+)
Misc Feature(7)644..646(+)
Exon (1)1..234
Gene:SNCA
Gene Synonym:
Exon (2)235..380
Gene:SNCA
Gene Synonym:
Exon (3)381..422
Gene:SNCA
Gene Synonym:
Exon (4)423..565
Gene:SNCA
Gene Synonym:
Exon (5)566..649
Gene:SNCA
Gene Synonym:
Exon (6)650..3211
Gene:SNCA
Gene Synonym:
Translation

Target ORF information:

RefSeq Version NM_001146054
Organism Homo sapiens (human)
Definition Homo sapiens synuclein, alpha (non A4 component of amyloid precursor) (SNCA), transcript variant 2, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
NM_001146054

ORF Insert Sequence:

1
61
121
181
241
301
361
421
ATGGATGTAT TCATGAAAGG ACTTTCAAAG GCCAAGGAGG GAGTTGTGGC TGCTGCTGAG 
AAAACCAAAC AGGGTGTGGC AGAAGCAGCA GGAAAGACAA AAGAGGGTGT TCTCTATGTA
GGCTCCAAAA CCAAGGAGGG AGTGGTGCAT GGTGTGGCAA CAGTGGCTGA GAAGACCAAA
GAGCAAGTGA CAAATGTTGG AGGAGCAGTG GTGACGGGTG TGACAGCAGT AGCCCAGAAG
ACAGTGGAGG GAGCAGGGAG CATTGCAGCA GCCACTGGCT TTGTCAAAAA GGACCAGTTG
GGCAAGAATG AAGAAGGAGC CCCACAGGAA GGAATTCTGG AAGATATGCC TGTGGATCCT
GACAATGAGG CTTATGAAAT GCCTTCTGAG GAAGGGTATC AAGACTACGA ACCTGAAGCC
TAA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OHu23545
Clone ID Related Accession (Same CDS sequence) NM_000345 , NM_001146054 , NM_001146055 , XM_011532208
Accession Version NM_001146055.1 Documents for ORF clone product in dufault vector
Sequence Information ORF Nucleotide Sequence (Length: 423bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags COA
ORF Insert Method CloneEZ® Seamless cloning technology
Insert Structure linear
Update Date 15-MAR-2015
Organism Homo sapiens (human)
Product alpha-synuclein isoform NACP140
Comment REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from DA391115.1 and AC097478.2. Transcript Variant: This variant (3) differs in the 5' UTR compared to variant 1. Variants 1, 2, and 3 all encode the same isoform (NACP140). Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: DA391115.1, BX423130.2 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2145743 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

1
61
121
181
241
301
361
421
ATGGATGTAT TCATGAAAGG ACTTTCAAAG GCCAAGGAGG GAGTTGTGGC TGCTGCTGAG 
AAAACCAAAC AGGGTGTGGC AGAAGCAGCA GGAAAGACAA AAGAGGGTGT TCTCTATGTA
GGCTCCAAAA CCAAGGAGGG AGTGGTGCAT GGTGTGGCAA CAGTGGCTGA GAAGACCAAA
GAGCAAGTGA CAAATGTTGG AGGAGCAGTG GTGACGGGTG TGACAGCAGT AGCCCAGAAG
ACAGTGGAGG GAGCAGGGAG CATTGCAGCA GCCACTGGCT TTGTCAAAAA GGACCAGTTG
GGCAAGAATG AAGAAGGAGC CCCACAGGAA GGAATTCTGG AAGATATGCC TGTGGATCCT
GACAATGAGG CTTATGAAAT GCCTTCTGAG GAAGGGTATC AAGACTACGA ACCTGAAGCC
TAA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq NP_001139527.1
CDS71..493
Misc Feature(1)53..55(+)
Misc Feature(2)71..466(+)
Misc Feature(3)71..73(+)
Misc Feature(4)128..271(+)
Misc Feature(5)329..331(+)
Misc Feature(6)443..445(+)
Misc Feature(7)455..457(+)
Exon (1)1..45
Gene:SNCA
Gene Synonym:
Exon (2)46..191
Gene:SNCA
Gene Synonym:
Exon (3)192..233
Gene:SNCA
Gene Synonym:
Exon (4)234..376
Gene:SNCA
Gene Synonym:
Exon (5)377..460
Gene:SNCA
Gene Synonym:
Exon (6)461..3022
Gene:SNCA
Gene Synonym:
Translation

Target ORF information:

RefSeq Version NM_001146055
Organism Homo sapiens (human)
Definition Homo sapiens synuclein, alpha (non A4 component of amyloid precursor) (SNCA), transcript variant 3, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
NM_001146055

ORF Insert Sequence:

1
61
121
181
241
301
361
421
ATGGATGTAT TCATGAAAGG ACTTTCAAAG GCCAAGGAGG GAGTTGTGGC TGCTGCTGAG 
AAAACCAAAC AGGGTGTGGC AGAAGCAGCA GGAAAGACAA AAGAGGGTGT TCTCTATGTA
GGCTCCAAAA CCAAGGAGGG AGTGGTGCAT GGTGTGGCAA CAGTGGCTGA GAAGACCAAA
GAGCAAGTGA CAAATGTTGG AGGAGCAGTG GTGACGGGTG TGACAGCAGT AGCCCAGAAG
ACAGTGGAGG GAGCAGGGAG CATTGCAGCA GCCACTGGCT TTGTCAAAAA GGACCAGTTG
GGCAAGAATG AAGAAGGAGC CCCACAGGAA GGAATTCTGG AAGATATGCC TGTGGATCCT
GACAATGAGG CTTATGAAAT GCCTTCTGAG GAAGGGTATC AAGACTACGA ACCTGAAGCC
TAA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

 
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