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STAT5B cDNA ORF clone, Homo sapiens (human)

Gene Symbol STAT5B
Entrez Gene ID 6777
Full Name signal transducer and activator of transcription 5B
Synonyms STAT5
General protein information
Preferred Names
signal transducer and activator of transcription 5B
Names
signal transducer and activator of transcription 5B
transcription factor STAT5B
Gene Type protein-coding
Organism Homo sapiens (human)
Genome

17

17q11.2

Summary The protein encoded by this gene is a member of the STAT family of transcription factors. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein mediates the signal transduction triggered by various cell ligands, such as IL2, IL4, CSF1, and different growth hormones. It has been shown to be involved in diverse biological processes, such as TCR signaling, apoptosis, adult mammary gland development, and sexual dimorphism of liver gene expression. This gene was found to fuse to retinoic acid receptor-alpha (RARA) gene in a small subset of acute promyelocytic leukemias (APLL). The dysregulation of the signaling pathways mediated by this protein may be the cause of the APLL. [provided by RefSeq, Jul 2008]. lac of sum
Disorder MIM:

604260

Disorder Html: Leukemia, acute promyelocytic, STAT5B/RARA type (3); Growth hormone

mRNA and Protein(s)

mRNA Protein Name
XM_005257625 XP_005257682 signal transducer and activator of transcription 5B isoform X1
XM_005257626 XP_005257683 signal transducer and activator of transcription 5B isoform X2
NM_012448 NP_036580 signal transducer and activator of transcription 5B



Homo sapiens (human) STAT5B NP_036580.2
Pan troglodytes (chimpanzee) STAT5B XP_001166251.1
Macaca mulatta (Rhesus monkey) STAT5B XP_001109317.2
Canis lupus familiaris (dog) STAT5B XP_548092.1
Bos taurus (cattle) STAT5B NP_777042.2
Mus musculus (house mouse) Stat5b NP_035619.3
Rattus norvegicus (Norway rat) Stat5b NP_071775.1
Gallus gallus (chicken) STAT5B NP_990110.1
Danio rerio (zebrafish) stat5.2 NP_001003984.1
Danio rerio (zebrafish) stat5.1 NP_919368.1
Caenorhabditis elegans sta-1 NP_502974.2
Xenopus (Silurana) tropicalis (western clawed frog) stat5b XP_002943467.1


GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following STAT5B gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the STAT5B cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

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***CloneID RefSeq Accession Definition **Vector *Turnaround time Price (USD) Select
OHu50617 XM_005257625 PREDICTED: Homo sapiens signal transducer and activator of transcription 5B (STAT5B), transcript variant X1, mRNA. pcDNA3.1+/C-(K)DYK or customized vector 12-14 $391.30
$559.00
OHu50618 XM_005257626 PREDICTED: Homo sapiens signal transducer and activator of transcription 5B (STAT5B), transcript variant X2, mRNA. pcDNA3.1+/C-(K)DYK or customized vector 7-9 $223.30
$319.00
OHu25538
NM_012448 Homo sapiens signal transducer and activator of transcription 5B (STAT5B), mRNA. pcDNA3.1+/C-(K)DYK or customized vector
in pcDNA3.1+/C-(K)DYK
$279.50-$391.30
$559.00

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.


CloneID OHu50617
Clone ID Related Accession (Same CDS sequence) XM_005257625
Accession Version XM_005257625.2 Documents for ORF clone product in dufault vector
Sequence Information ORF Nucleotide Sequence (Length: 2082bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ® Seamless cloning technology
Insert Structure linear
Update Date 12-MAR-2015
Organism Homo sapiens (human)
Product signal transducer and activator of transcription 5B isoform X1
Comment MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NT_010783.16) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Mar 12, 2015 this sequence version replaced gi:530412764. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Homo sapiens Annotation Release 107 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 6.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
1501
1561
1621
1681
1741
1801
1861
1921
1981
2041
ATGAACACGT ATGACCGCTG CCCCATGGAG CTGGTCCGCT GCATCCGCCA TATATTGTAC 
AATGAACAGA GGTTGGTCCG AGAAGCCAAC AATGGTAGCT CTCCAGCTGG AAGCCTTGCT
GATGCCATGT CCCAGAAACA CCTCCAGATC AACCAGACGT TTGAGGAGCT GCGACTGGTC
ACGCAGGACA CAGAGAATGA GTTAAAAAAG CTGCAGCAGA CTCAGGAGTA CTTCATCATC
CAGTACCAGG AGAGCCTGAG GATCCAAGCT CAGTTTGGCC CGCTGGCCCA GCTGAGCCCC
CAGGAGCGTC TGAGCCGGGA GACGGCCCTC CAGCAGAAGC AGGTGTCTCT GGAGGCCTGG
TTGCAGCGTG AGGCACAGAC ACTGCAGCAG TACCGCGTGG AGCTGGCCGA GAAGCACCAG
AAGACCCTGC AGCTGCTGCG GAAGCAGCAG ACCATCATCC TGGATGACGA GCTGATCCAG
TGGAAGCGGC GGCAGCAGCT GGCCGGGAAC GGCGGGCCCC CCGAGGGCAG CCTGGACGTG
CTACAGTCCT GGTGTGAGAA GTTGGCCGAG ATCATCTGGC AGAACCGGCA GCAGATCCGC
AGGGCTGAGC ACCTCTGCCA GCAGCTGCCC ATCCCCGGCC CAGTGGAGGA GATGCTGGCC
GAGGTCAACG CCACCATCAC GGACATTATC TCAGCCCTGG TGACCAGCAC GTTCATCATT
GAGAAGCAGC CTCCTCAGGT CCTGAAGACC CAGACCAAGT TTGCAGCCAC TGTGCGCCTG
CTGGTGGGCG GGAAGCTGAA CGTGCACATG AACCCCCCCC AGGTGAAGGC CACCATCATC
AGTGAGCAGC AGGCCAAGTC TCTGCTCAAG AACGAGAACA CCCGCAATGA TTACAGTGGC
GAGATCTTGA ACAACTGCTG CGTCATGGAG TACCACCAAG CCACAGGCAC CCTTAGTGCC
CACTTCAGGA ATATGTCCCT GAAACGAATT AAGAGGTCAG ACCGTCGTGG GGCAGAGTCG
GTGACAGAAG AAAAATTTAC AATCCTGTTT GAATCCCAGT TCAGTGTTGG TGGAAATGAG
CTGGTTTTTC AAGTCAAGAC CCTGTCCCTG CCAGTGGTGG TGATCGTTCA TGGCAGCCAG
GACAACAATG CGACGGCCAC TGTTCTCTGG GACAATGCTT TTGCAGAGCC TGGCAGGGTG
CCATTTGCCG TGCCTGACAA AGTGCTGTGG CCACAGCTGT GTGAGGCGCT CAACATGAAA
TTCAAGGCCG AAGTGCAGAG CAACCGGGGC CTGACCAAGG AGAACCTCGT GTTCCTGGCG
CAGAAACTGT TCAACAACAG CAGCAGCCAC CTGGAGGACT ACAGTGGCCT GTCTGTGTCC
TGGTCCCAGT TCAACAGGGA GAATTTACCA GGACGGAATT ACACTTTCTG GCAATGGTTT
GACGGTGTGA TGGAAGTGTT AAAAAAACAT CTCAAGCCTC ATTGGAATGA TGGGGCCATT
TTGGGGTTTG TAAACAAGCA ACAGGCCCAT GACCTACTCA TTAACAAGCC AGATGGGACC
TTCCTCCTGA GATTCAGTGA CTCAGAAATT GGCGGCATCA CCATTGCTTG GAAGTTTGAT
TCTCAGGAAA GAATGTTTTG GAATCTGATG CCTTTTACCA CCAGAGACTT CTCCATTCGG
TCCCTAGCCG ACCGCTTGGG AGACTTGAAT TACCTTATCT ACGTGTTTCC TGATCGGCCA
AAAGATGAAG TATACTCCAA ATACTACACA CCAGTTCCCT GCGAGTCTGC TACTGCTAAA
GCTGTTGATG GATACGTGAA GCCACAGATC AAGCAAGTGG TCCCTGAGTT TGTGAACGCA
TCTGCAGATG CCGGGGGCGG CAGCGCCACG TACATGGACC AGGCCCCCTC CCCAGCTGTG
TGTCCCCAGG CTCACTATAA CATGTACCCA CAGAACCCTG ACTCAGTCCT TGACACCGAT
GGGGACTTCG ATCTGGAGGA CACAATGGAC GTAGCGCGGC GTGTGGAGGA GCTCCTGGGC
CGGCCAATGG ACAGTCAGTG GATCCCGCAC GCACAATCGT GA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq XP_005257682.1
CDS87..2168
Misc Feature(1)90..179(+)
Misc Feature(2)216..794(+)
Misc Feature(3)798..1553(+)
Misc Feature(4)1521..1955(+)
Misc Feature(5)1602..1736(+)
Misc Feature(6)1731..1781(+)
Misc Feature(7)1761..1916(+)
Translation

Target ORF information:

RefSeq Version XM_005257625
Organism Homo sapiens (human)
Definition PREDICTED: Homo sapiens signal transducer and activator of transcription 5B (STAT5B), transcript variant X1, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
XM_005257625

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
1501
1561
1621
1681
1741
1801
1861
1921
1981
2041
ATGAACACGT ATGACCGCTG CCCCATGGAG CTGGTCCGCT GCATCCGCCA TATATTGTAC 
AATGAACAGA GGTTGGTCCG AGAAGCCAAC AATGGTAGCT CTCCAGCTGG AAGCCTTGCT
GATGCCATGT CCCAGAAACA CCTCCAGATC AACCAGACGT TTGAGGAGCT GCGACTGGTC
ACGCAGGACA CAGAGAATGA GTTAAAAAAG CTGCAGCAGA CTCAGGAGTA CTTCATCATC
CAGTACCAGG AGAGCCTGAG GATCCAAGCT CAGTTTGGCC CGCTGGCCCA GCTGAGCCCC
CAGGAGCGTC TGAGCCGGGA GACGGCCCTC CAGCAGAAGC AGGTGTCTCT GGAGGCCTGG
TTGCAGCGTG AGGCACAGAC ACTGCAGCAG TACCGCGTGG AGCTGGCCGA GAAGCACCAG
AAGACCCTGC AGCTGCTGCG GAAGCAGCAG ACCATCATCC TGGATGACGA GCTGATCCAG
TGGAAGCGGC GGCAGCAGCT GGCCGGGAAC GGCGGGCCCC CCGAGGGCAG CCTGGACGTG
CTACAGTCCT GGTGTGAGAA GTTGGCCGAG ATCATCTGGC AGAACCGGCA GCAGATCCGC
AGGGCTGAGC ACCTCTGCCA GCAGCTGCCC ATCCCCGGCC CAGTGGAGGA GATGCTGGCC
GAGGTCAACG CCACCATCAC GGACATTATC TCAGCCCTGG TGACCAGCAC GTTCATCATT
GAGAAGCAGC CTCCTCAGGT CCTGAAGACC CAGACCAAGT TTGCAGCCAC TGTGCGCCTG
CTGGTGGGCG GGAAGCTGAA CGTGCACATG AACCCCCCCC AGGTGAAGGC CACCATCATC
AGTGAGCAGC AGGCCAAGTC TCTGCTCAAG AACGAGAACA CCCGCAATGA TTACAGTGGC
GAGATCTTGA ACAACTGCTG CGTCATGGAG TACCACCAAG CCACAGGCAC CCTTAGTGCC
CACTTCAGGA ATATGTCCCT GAAACGAATT AAGAGGTCAG ACCGTCGTGG GGCAGAGTCG
GTGACAGAAG AAAAATTTAC AATCCTGTTT GAATCCCAGT TCAGTGTTGG TGGAAATGAG
CTGGTTTTTC AAGTCAAGAC CCTGTCCCTG CCAGTGGTGG TGATCGTTCA TGGCAGCCAG
GACAACAATG CGACGGCCAC TGTTCTCTGG GACAATGCTT TTGCAGAGCC TGGCAGGGTG
CCATTTGCCG TGCCTGACAA AGTGCTGTGG CCACAGCTGT GTGAGGCGCT CAACATGAAA
TTCAAGGCCG AAGTGCAGAG CAACCGGGGC CTGACCAAGG AGAACCTCGT GTTCCTGGCG
CAGAAACTGT TCAACAACAG CAGCAGCCAC CTGGAGGACT ACAGTGGCCT GTCTGTGTCC
TGGTCCCAGT TCAACAGGGA GAATTTACCA GGACGGAATT ACACTTTCTG GCAATGGTTT
GACGGTGTGA TGGAAGTGTT AAAAAAACAT CTCAAGCCTC ATTGGAATGA TGGGGCCATT
TTGGGGTTTG TAAACAAGCA ACAGGCCCAT GACCTACTCA TTAACAAGCC AGATGGGACC
TTCCTCCTGA GATTCAGTGA CTCAGAAATT GGCGGCATCA CCATTGCTTG GAAGTTTGAT
TCTCAGGAAA GAATGTTTTG GAATCTGATG CCTTTTACCA CCAGAGACTT CTCCATTCGG
TCCCTAGCCG ACCGCTTGGG AGACTTGAAT TACCTTATCT ACGTGTTTCC TGATCGGCCA
AAAGATGAAG TATACTCCAA ATACTACACA CCAGTTCCCT GCGAGTCTGC TACTGCTAAA
GCTGTTGATG GATACGTGAA GCCACAGATC AAGCAAGTGG TCCCTGAGTT TGTGAACGCA
TCTGCAGATG CCGGGGGCGG CAGCGCCACG TACATGGACC AGGCCCCCTC CCCAGCTGTG
TGTCCCCAGG CTCACTATAA CATGTACCCA CAGAACCCTG ACTCAGTCCT TGACACCGAT
GGGGACTTCG ATCTGGAGGA CACAATGGAC GTAGCGCGGC GTGTGGAGGA GCTCCTGGGC
CGGCCAATGG ACAGTCAGTG GATCCCGCAC GCACAATCGT GA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OHu50618
Clone ID Related Accession (Same CDS sequence) XM_005257626
Accession Version XM_005257626.3 Documents for ORF clone product in dufault vector
Sequence Information ORF Nucleotide Sequence (Length: 1494bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ® Seamless cloning technology
Insert Structure linear
Update Date 12-MAR-2015
Organism Homo sapiens (human)
Product signal transducer and activator of transcription 5B isoform X2
Comment MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NT_010783.16) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Mar 12, 2015 this sequence version replaced gi:578831312. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Homo sapiens Annotation Release 107 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 6.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
ATGGCTGTGT GGATACAAGC TCAGCAGCTC CAAGGAGAAG CCCTTCATCA GATGCAAGCG 
TTATATGGCC AGCATTTTCC CATTGAGGTG CGGCATTATT TATCCCAGTG GATTGAAAGC
CAAGCATGGG ACTCAGTAGA TCTTGATAAT CCACAGGAGA ACATTAAGGC CACCCAGCTC
CTGGAGGGCC TGGTGCAGGA GCTGCAGAAG AAGGCAGAGC ACCAGGTGGG GGAAGATGGG
TTTTTACTGA AGATCAAGCT GGGGCACTAT GCCACACAGC TCCAGAACAC GTATGACCGC
TGCCCCATGG AGCTGGTCCG CTGCATCCGC CATATATTGT ACAATGAACA GAGGTTGGTC
CGAGAAGCCA ACAATGGTAG CTCTCCAGCT GGAAGCCTTG CTGATGCCAT GTCCCAGAAA
CACCTCCAGA TCAACCAGAC GTTTGAGGAG CTGCGACTGG TCACGCAGGA CACAGAGAAT
GAGTTAAAAA AGCTGCAGCA GACTCAGGAG TACTTCATCA TCCAGTACCA GGAGAGCCTG
AGGATCCAAG CTCAGTTTGG CCCGCTGGCC CAGCTGAGCC CCCAGGAGCG TCTGAGCCGG
GAGACGGCCC TCCAGCAGAA GCAGGTGTCT CTGGAGGCCT GGTTGCAGCG TGAGGCACAG
ACACTGCAGC AGTACCGCGT GGAGCTGGCC GAGAAGCACC AGAAGACCCT GCAGCTGCTG
CGGAAGCAGC AGACCATCAT CCTGGATGAC GAGCTGATCC AGTGGAAGCG GCGGCAGCAG
CTGGCCGGGA ACGGCGGGCC CCCCGAGGGC AGCCTGGACG TGCTACAGTC CTGGTGTGAG
AAGTTGGCCG AGATCATCTG GCAGAACCGG CAGCAGATCC GCAGGGCTGA GCACCTCTGC
CAGCAGCTGC CCATCCCCGG CCCAGTGGAG GAGATGCTGG CCGAGGTCAA CGCCACCATC
ACGGACATTA TCTCAGCCCT GGTGACCAGC ACGTTCATCA TTGAGAAGCA GCCTCCTCAG
GTCCTGAAGA CCCAGACCAA GTTTGCAGCC ACTGTGCGCC TGCTGGTGGG CGGGAAGCTG
AACGTGCACA TGAACCCCCC CCAGGTGAAG GCCACCATCA TCAGTGAGCA GCAGGCCAAG
TCTCTGCTCA AGAACGAGAA CACCCGCAAT GATTACAGTG GCGAGATCTT GAACAACTGC
TGCGTCATGG AGTACCACCA AGCCACAGGC ACCCTTAGTG CCCACTTCAG GAATATGTCC
CTGAAACGAA TTAAGAGGTC AGACCGTCGT GGGGCAGAGT CGGTGACAGA AGAAAAATTT
ACAATCCTGT TTGAATCCCA GTTCAGTGTT GGTGGAAATG AGCTGGTTTT TCAAGTCAAG
ACCCTGTCCC TGCCAGTGGT GGTGATCGTT CATGGCAGCC AGGACAACAA TGCGACGGCC
ACTGTTCTCT GGGACAATGC TTTTGCAGAG CCTAATATAG GATTTGACTG TTAG

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq XP_005257683.1
CDS224..1717
Misc Feature(1)227..601(+)
Misc Feature(2)635..1213(+)
Misc Feature(3)1217..>1696(+)
Translation

Target ORF information:

RefSeq Version XM_005257626
Organism Homo sapiens (human)
Definition PREDICTED: Homo sapiens signal transducer and activator of transcription 5B (STAT5B), transcript variant X2, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
XM_005257626

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
ATGGCTGTGT GGATACAAGC TCAGCAGCTC CAAGGAGAAG CCCTTCATCA GATGCAAGCG 
TTATATGGCC AGCATTTTCC CATTGAGGTG CGGCATTATT TATCCCAGTG GATTGAAAGC
CAAGCATGGG ACTCAGTAGA TCTTGATAAT CCACAGGAGA ACATTAAGGC CACCCAGCTC
CTGGAGGGCC TGGTGCAGGA GCTGCAGAAG AAGGCAGAGC ACCAGGTGGG GGAAGATGGG
TTTTTACTGA AGATCAAGCT GGGGCACTAT GCCACACAGC TCCAGAACAC GTATGACCGC
TGCCCCATGG AGCTGGTCCG CTGCATCCGC CATATATTGT ACAATGAACA GAGGTTGGTC
CGAGAAGCCA ACAATGGTAG CTCTCCAGCT GGAAGCCTTG CTGATGCCAT GTCCCAGAAA
CACCTCCAGA TCAACCAGAC GTTTGAGGAG CTGCGACTGG TCACGCAGGA CACAGAGAAT
GAGTTAAAAA AGCTGCAGCA GACTCAGGAG TACTTCATCA TCCAGTACCA GGAGAGCCTG
AGGATCCAAG CTCAGTTTGG CCCGCTGGCC CAGCTGAGCC CCCAGGAGCG TCTGAGCCGG
GAGACGGCCC TCCAGCAGAA GCAGGTGTCT CTGGAGGCCT GGTTGCAGCG TGAGGCACAG
ACACTGCAGC AGTACCGCGT GGAGCTGGCC GAGAAGCACC AGAAGACCCT GCAGCTGCTG
CGGAAGCAGC AGACCATCAT CCTGGATGAC GAGCTGATCC AGTGGAAGCG GCGGCAGCAG
CTGGCCGGGA ACGGCGGGCC CCCCGAGGGC AGCCTGGACG TGCTACAGTC CTGGTGTGAG
AAGTTGGCCG AGATCATCTG GCAGAACCGG CAGCAGATCC GCAGGGCTGA GCACCTCTGC
CAGCAGCTGC CCATCCCCGG CCCAGTGGAG GAGATGCTGG CCGAGGTCAA CGCCACCATC
ACGGACATTA TCTCAGCCCT GGTGACCAGC ACGTTCATCA TTGAGAAGCA GCCTCCTCAG
GTCCTGAAGA CCCAGACCAA GTTTGCAGCC ACTGTGCGCC TGCTGGTGGG CGGGAAGCTG
AACGTGCACA TGAACCCCCC CCAGGTGAAG GCCACCATCA TCAGTGAGCA GCAGGCCAAG
TCTCTGCTCA AGAACGAGAA CACCCGCAAT GATTACAGTG GCGAGATCTT GAACAACTGC
TGCGTCATGG AGTACCACCA AGCCACAGGC ACCCTTAGTG CCCACTTCAG GAATATGTCC
CTGAAACGAA TTAAGAGGTC AGACCGTCGT GGGGCAGAGT CGGTGACAGA AGAAAAATTT
ACAATCCTGT TTGAATCCCA GTTCAGTGTT GGTGGAAATG AGCTGGTTTT TCAAGTCAAG
ACCCTGTCCC TGCCAGTGGT GGTGATCGTT CATGGCAGCC AGGACAACAA TGCGACGGCC
ACTGTTCTCT GGGACAATGC TTTTGCAGAG CCTAATATAG GATTTGACTG TTAG

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OHu25538
Clone ID Related Accession (Same CDS sequence) NM_012448
Accession Version NM_012448.3 Documents for ORF clone product in dufault vector
Sequence Information ORF Nucleotide Sequence (Length: 2364bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags COA
ORF Insert Method CloneEZ® Seamless cloning technology
Insert Structure linear
Update Date 15-MAR-2015
Organism Homo sapiens (human)
Product signal transducer and activator of transcription 5B
Comment REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from BC065227.1 and U47686.1. This sequence is a reference standard in the RefSeqGene project. On Feb 11, 2004 this sequence version replaced gi:21618343. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC065227.1, AB208920.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
1501
1561
1621
1681
1741
1801
1861
1921
1981
2041
2101
2161
2221
2281
2341
ATGGCTGTGT GGATACAAGC TCAGCAGCTC CAAGGAGAAG CCCTTCATCA GATGCAAGCG 
TTATATGGCC AGCATTTTCC CATTGAGGTG CGGCATTATT TATCCCAGTG GATTGAAAGC
CAAGCATGGG ACTCAGTAGA TCTTGATAAT CCACAGGAGA ACATTAAGGC CACCCAGCTC
CTGGAGGGCC TGGTGCAGGA GCTGCAGAAG AAGGCAGAGC ACCAGGTGGG GGAAGATGGG
TTTTTACTGA AGATCAAGCT GGGGCACTAT GCCACACAGC TCCAGAACAC GTATGACCGC
TGCCCCATGG AGCTGGTCCG CTGCATCCGC CATATATTGT ACAATGAACA GAGGTTGGTC
CGAGAAGCCA ACAATGGTAG CTCTCCAGCT GGAAGCCTTG CTGATGCCAT GTCCCAGAAA
CACCTCCAGA TCAACCAGAC GTTTGAGGAG CTGCGACTGG TCACGCAGGA CACAGAGAAT
GAGTTAAAAA AGCTGCAGCA GACTCAGGAG TACTTCATCA TCCAGTACCA GGAGAGCCTG
AGGATCCAAG CTCAGTTTGG CCCGCTGGCC CAGCTGAGCC CCCAGGAGCG TCTGAGCCGG
GAGACGGCCC TCCAGCAGAA GCAGGTGTCT CTGGAGGCCT GGTTGCAGCG TGAGGCACAG
ACACTGCAGC AGTACCGCGT GGAGCTGGCC GAGAAGCACC AGAAGACCCT GCAGCTGCTG
CGGAAGCAGC AGACCATCAT CCTGGATGAC GAGCTGATCC AGTGGAAGCG GCGGCAGCAG
CTGGCCGGGA ACGGCGGGCC CCCCGAGGGC AGCCTGGACG TGCTACAGTC CTGGTGTGAG
AAGTTGGCCG AGATCATCTG GCAGAACCGG CAGCAGATCC GCAGGGCTGA GCACCTCTGC
CAGCAGCTGC CCATCCCCGG CCCAGTGGAG GAGATGCTGG CCGAGGTCAA CGCCACCATC
ACGGACATTA TCTCAGCCCT GGTGACCAGC ACGTTCATCA TTGAGAAGCA GCCTCCTCAG
GTCCTGAAGA CCCAGACCAA GTTTGCAGCC ACTGTGCGCC TGCTGGTGGG CGGGAAGCTG
AACGTGCACA TGAACCCCCC CCAGGTGAAG GCCACCATCA TCAGTGAGCA GCAGGCCAAG
TCTCTGCTCA AGAACGAGAA CACCCGCAAT GATTACAGTG GCGAGATCTT GAACAACTGC
TGCGTCATGG AGTACCACCA AGCCACAGGC ACCCTTAGTG CCCACTTCAG GAATATGTCC
CTGAAACGAA TTAAGAGGTC AGACCGTCGT GGGGCAGAGT CGGTGACAGA AGAAAAATTT
ACAATCCTGT TTGAATCCCA GTTCAGTGTT GGTGGAAATG AGCTGGTTTT TCAAGTCAAG
ACCCTGTCCC TGCCAGTGGT GGTGATCGTT CATGGCAGCC AGGACAACAA TGCGACGGCC
ACTGTTCTCT GGGACAATGC TTTTGCAGAG CCTGGCAGGG TGCCATTTGC CGTGCCTGAC
AAAGTGCTGT GGCCACAGCT GTGTGAGGCG CTCAACATGA AATTCAAGGC CGAAGTGCAG
AGCAACCGGG GCCTGACCAA GGAGAACCTC GTGTTCCTGG CGCAGAAACT GTTCAACAAC
AGCAGCAGCC ACCTGGAGGA CTACAGTGGC CTGTCTGTGT CCTGGTCCCA GTTCAACAGG
GAGAATTTAC CAGGACGGAA TTACACTTTC TGGCAATGGT TTGACGGTGT GATGGAAGTG
TTAAAAAAAC ATCTCAAGCC TCATTGGAAT GATGGGGCCA TTTTGGGGTT TGTAAACAAG
CAACAGGCCC ATGACCTACT CATTAACAAG CCAGATGGGA CCTTCCTCCT GAGATTCAGT
GACTCAGAAA TTGGCGGCAT CACCATTGCT TGGAAGTTTG ATTCTCAGGA AAGAATGTTT
TGGAATCTGA TGCCTTTTAC CACCAGAGAC TTCTCCATTC GGTCCCTAGC CGACCGCTTG
GGAGACTTGA ATTACCTTAT CTACGTGTTT CCTGATCGGC CAAAAGATGA AGTATACTCC
AAATACTACA CACCAGTTCC CTGCGAGTCT GCTACTGCTA AAGCTGTTGA TGGATACGTG
AAGCCACAGA TCAAGCAAGT GGTCCCTGAG TTTGTGAACG CATCTGCAGA TGCCGGGGGC
GGCAGCGCCA CGTACATGGA CCAGGCCCCC TCCCCAGCTG TGTGTCCCCA GGCTCACTAT
AACATGTACC CACAGAACCC TGACTCAGTC CTTGACACCG ATGGGGACTT CGATCTGGAG
GACACAATGG ACGTAGCGCG GCGTGTGGAG GAGCTCCTGG GCCGGCCAAT GGACAGTCAG
TGGATCCCGC ACGCACAATC GTGA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq NP_036580.2
CDS170..2533
Misc Feature(1)164..166(+)
Misc Feature(2)173..547(+)
Misc Feature(3)548..550(+)
Misc Feature(4)551..553(+)
Misc Feature(5)581..1159(+)
Misc Feature(6)746..748(+)
Misc Feature(7)863..1132(+)
Misc Feature(8)1163..1918(+)
Misc Feature(9)1886..2320(+)
Misc Feature(10)1967..2101(+)
Misc Feature(11)2096..2146(+)
Misc Feature(12)2126..2281(+)
Misc Feature(13)2204..2206(+)
Misc Feature(14)2264..2266(+)
Misc Feature(15)2264..2266(+)
Misc Feature(16)2264..2266(+)
Misc Feature(17)2264..2266(+)
Misc Feature(18)2342..2344(+)
Misc Feature(19)2360..2362(+)
Misc Feature(20)2387..2389(+)
Misc Feature(21)2396..2398(+)
Exon (1)1..159
Gene:STAT5B
Gene Synonym:
Exon (2)160..297
Gene:STAT5B
Gene Synonym:
Exon (3)298..454
Gene:STAT5B
Gene Synonym:
Exon (4)455..544
Gene:STAT5B
Gene Synonym:
Exon (5)545..719
Gene:STAT5B
Gene Synonym:
Exon (6)720..850
Gene:STAT5B
Gene Synonym:
Exon (7)851..1002
Gene:STAT5B
Gene Synonym:
Exon (8)1003..1158
Gene:STAT5B
Gene Synonym:
Exon (9)1159..1338
Gene:STAT5B
Gene Synonym:
Exon (10)1339..1426
Gene:STAT5B
Gene Synonym:
Exon (11)1427..1549
Gene:STAT5B
Gene Synonym:
Exon (12)1550..1642
Gene:STAT5B
Gene Synonym:
Exon (13)1643..1849
Gene:STAT5B
Gene Synonym:
Exon (14)1850..1944
Gene:STAT5B
Gene Synonym:
Exon (15)1945..2075
Gene:STAT5B
Gene Synonym:
Exon (16)2076..2246
Gene:STAT5B
Gene Synonym:
Exon (17)2247..2298
Gene:STAT5B
Gene Synonym:
Exon (18)2299..2406
Gene:STAT5B
Gene Synonym:
Exon (19)2407..5094
Gene:STAT5B
Gene Synonym:
Translation

Target ORF information:

RefSeq Version NM_012448
Organism Homo sapiens (human)
Definition Homo sapiens signal transducer and activator of transcription 5B (STAT5B), mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
NM_012448

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
1501
1561
1621
1681
1741
1801
1861
1921
1981
2041
2101
2161
2221
2281
2341
ATGGCTGTGT GGATACAAGC TCAGCAGCTC CAAGGAGAAG CCCTTCATCA GATGCAAGCG 
TTATATGGCC AGCATTTTCC CATTGAGGTG CGGCATTATT TATCCCAGTG GATTGAAAGC
CAAGCATGGG ACTCAGTAGA TCTTGATAAT CCACAGGAGA ACATTAAGGC CACCCAGCTC
CTGGAGGGCC TGGTGCAGGA GCTGCAGAAG AAGGCAGAGC ACCAGGTGGG GGAAGATGGG
TTTTTACTGA AGATCAAGCT GGGGCACTAT GCCACACAGC TCCAGAACAC GTATGACCGC
TGCCCCATGG AGCTGGTCCG CTGCATCCGC CATATATTGT ACAATGAACA GAGGTTGGTC
CGAGAAGCCA ACAATGGTAG CTCTCCAGCT GGAAGCCTTG CTGATGCCAT GTCCCAGAAA
CACCTCCAGA TCAACCAGAC GTTTGAGGAG CTGCGACTGG TCACGCAGGA CACAGAGAAT
GAGTTAAAAA AGCTGCAGCA GACTCAGGAG TACTTCATCA TCCAGTACCA GGAGAGCCTG
AGGATCCAAG CTCAGTTTGG CCCGCTGGCC CAGCTGAGCC CCCAGGAGCG TCTGAGCCGG
GAGACGGCCC TCCAGCAGAA GCAGGTGTCT CTGGAGGCCT GGTTGCAGCG TGAGGCACAG
ACACTGCAGC AGTACCGCGT GGAGCTGGCC GAGAAGCACC AGAAGACCCT GCAGCTGCTG
CGGAAGCAGC AGACCATCAT CCTGGATGAC GAGCTGATCC AGTGGAAGCG GCGGCAGCAG
CTGGCCGGGA ACGGCGGGCC CCCCGAGGGC AGCCTGGACG TGCTACAGTC CTGGTGTGAG
AAGTTGGCCG AGATCATCTG GCAGAACCGG CAGCAGATCC GCAGGGCTGA GCACCTCTGC
CAGCAGCTGC CCATCCCCGG CCCAGTGGAG GAGATGCTGG CCGAGGTCAA CGCCACCATC
ACGGACATTA TCTCAGCCCT GGTGACCAGC ACGTTCATCA TTGAGAAGCA GCCTCCTCAG
GTCCTGAAGA CCCAGACCAA GTTTGCAGCC ACTGTGCGCC TGCTGGTGGG CGGGAAGCTG
AACGTGCACA TGAACCCCCC CCAGGTGAAG GCCACCATCA TCAGTGAGCA GCAGGCCAAG
TCTCTGCTCA AGAACGAGAA CACCCGCAAT GATTACAGTG GCGAGATCTT GAACAACTGC
TGCGTCATGG AGTACCACCA AGCCACAGGC ACCCTTAGTG CCCACTTCAG GAATATGTCC
CTGAAACGAA TTAAGAGGTC AGACCGTCGT GGGGCAGAGT CGGTGACAGA AGAAAAATTT
ACAATCCTGT TTGAATCCCA GTTCAGTGTT GGTGGAAATG AGCTGGTTTT TCAAGTCAAG
ACCCTGTCCC TGCCAGTGGT GGTGATCGTT CATGGCAGCC AGGACAACAA TGCGACGGCC
ACTGTTCTCT GGGACAATGC TTTTGCAGAG CCTGGCAGGG TGCCATTTGC CGTGCCTGAC
AAAGTGCTGT GGCCACAGCT GTGTGAGGCG CTCAACATGA AATTCAAGGC CGAAGTGCAG
AGCAACCGGG GCCTGACCAA GGAGAACCTC GTGTTCCTGG CGCAGAAACT GTTCAACAAC
AGCAGCAGCC ACCTGGAGGA CTACAGTGGC CTGTCTGTGT CCTGGTCCCA GTTCAACAGG
GAGAATTTAC CAGGACGGAA TTACACTTTC TGGCAATGGT TTGACGGTGT GATGGAAGTG
TTAAAAAAAC ATCTCAAGCC TCATTGGAAT GATGGGGCCA TTTTGGGGTT TGTAAACAAG
CAACAGGCCC ATGACCTACT CATTAACAAG CCAGATGGGA CCTTCCTCCT GAGATTCAGT
GACTCAGAAA TTGGCGGCAT CACCATTGCT TGGAAGTTTG ATTCTCAGGA AAGAATGTTT
TGGAATCTGA TGCCTTTTAC CACCAGAGAC TTCTCCATTC GGTCCCTAGC CGACCGCTTG
GGAGACTTGA ATTACCTTAT CTACGTGTTT CCTGATCGGC CAAAAGATGA AGTATACTCC
AAATACTACA CACCAGTTCC CTGCGAGTCT GCTACTGCTA AAGCTGTTGA TGGATACGTG
AAGCCACAGA TCAAGCAAGT GGTCCCTGAG TTTGTGAACG CATCTGCAGA TGCCGGGGGC
GGCAGCGCCA CGTACATGGA CCAGGCCCCC TCCCCAGCTG TGTGTCCCCA GGCTCACTAT
AACATGTACC CACAGAACCC TGACTCAGTC CTTGACACCG ATGGGGACTT CGATCTGGAG
GACACAATGG ACGTAGCGCG GCGTGTGGAG GAGCTCCTGG GCCGGCCAAT GGACAGTCAG
TGGATCCCGC ACGCACAATC GTGA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

 
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