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TFR2 cDNA ORF clone, Homo sapiens(Human)

Gene Symbol TFR2
Entrez Gene ID 7036
Full Name transferrin receptor 2
Synonyms HFE3,TFRC2
General protein information
Preferred Names

transferrin receptor 2

Names

transferrin receptor protein 2

Gene Type protein-coding
Organism Homo sapiens(Human)
Genome

7

7q22.1

Summary This gene encodes a single-pass type II membrane protein, which is a member of the transferrin receptor-like family. This protein mediates cellular uptake of transferrin-bound iron, and may be involved in iron metabolism, hepatocyte function and erythrocyte differentiation. Mutations in this gene have been associated with hereditary hemochromatosis type III. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, May 2011].
Disorder MIM:

604720

Disorder Html: Hemochromatosis, type 3, 604250 (3)

mRNA and Protein(s)

mRNA Protein Name
XM_005250553.4 XP_005250610.1 transferrin receptor protein 2 isoform X1
XM_005250553.3 XP_005250610.1 transferrin receptor protein 2 isoform X1
XM_017012573.1 XP_016868062.1 transferrin receptor protein 2 isoform X1
NM_003227.3 NP_003218.2 transferrin receptor protein 2 isoform 1
NM_001206855.1 NP_001193784.1 transferrin receptor protein 2 isoform 2



Bos taurus (cattle) TFR2 NP_001171212.1
Rattus norvegicus (Norway rat) Tfr2 NP_001099386.1
Mus musculus (house mouse) Tfr2 NP_056614.3
Homo sapiens (human) TFR2 NP_003218.2
Pan troglodytes (chimpanzee) TFR2 XP_003318698.1
Canis lupus familiaris (dog) TFR2 XP_005621095.1
Danio rerio (zebrafish) tfr2 NP_001009916.1
Macaca mulatta (rhesus monkey) TFR2 XP_001113151.1


Related articles in PubMed

Novel pathway for iron deficiency in pediatric non-alcoholic steatohepatitis.
Moya D, Baker SS, Liu W, Garrick M, Kozielski R, Baker RD, Zhu L
Clinical nutrition (Edinburgh, Scotland)34(3)549-56(2015 Jun)

Erythropoiesis and transferrin receptors.
Moura IC, Hermine O, Lacombe C, Mayeux P
Current opinion in hematology22(3)193-8(2015 May)

Regulation of cell surface transferrin receptor-2 by iron-dependent cleavage and release of a soluble form.
Pagani A, Vieillevoye M, Nai A, Rausa M, Ladli M, Lacombe C, Mayeux P, Verdier F, Camaschella C, Silvestri L
Haematologica100(4)458-65(2015 Apr)

CD81 promotes both the degradation of transferrin receptor 2 (TfR2) and the Tfr2-mediated maintenance of hepcidin expression.
Chen J, Enns CA
The Journal of biological chemistry290(12)7841-50(2015 Mar)

Novel loci affecting iron homeostasis and their effects in individuals at risk for hemochromatosis.
Benyamin B, Esko T, Ried JS, Radhakrishnan A, Vermeulen SH, Traglia M, Gögele M, Anderson D, Broer L, Podmore C, Luan J, Kutalik Z, Sanna S, van der Meer P, Tanaka T, Wang F, Westra HJ, Franke L, Mihailov E, Milani L, Hälldin J, Häldin J, Winkelmann J, Meitinger T, Thiery J, Peters A, Waldenberger M, Rendon A, Jolley J, Sambrook J, Kiemeney LA, Sweep FC, Sala CF, Schwienbacher C, Pichler I, Hui J, Demirkan A, Isaacs A, Amin N, Steri M, Waeber G, Verweij N, Powell JE, Nyholt DR, Heath AC, Madden PA, Visscher PM, Wright MJ, Montgomery GW, Martin NG, Hernandez D, Bandinelli S, van der Harst P, Uda M, Vollenweider P, Scott RA, Langenberg C, Wareham NJ, , van Duijn C, Beilby J, Pramstaller PP, Hicks AA, Ouwehand WH, Oexle K, Gieger C, Metspalu A, Camaschella C, Toniolo D, Swinkels DW, Whitfield JB
Nature communications54926(2014 Oct)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

In line with a status of iron deficiency, gene expression studies suggested decreased expression of transferrin and transferrin receptor 2 in non-alcoholic steatohepatitis livers
Title: Novel pathway for iron deficiency in pediatric non-alcoholic steatohepatitis.

Our results indicate that membrane transferrin receptor-2, a sensor of circulating iron, is released from the cell membrane in iron deficiency.
Title: Regulation of cell surface transferrin receptor-2 by iron-dependent cleavage and release of a soluble form.

results suggest that down-regulation of CD81 by GRAIL targets TfR2 for degradation
Title: CD81 promotes both the degradation of transferrin receptor 2 (TfR2) and the Tfr2-mediated maintenance of hepcidin expression.

Authors investigated the expression of TfR1 and TfR2 in human HCC tissues by immunohistochemistry, the first report demonstrating TfR2 expression immunohistochemically in human HCC.
Title: Immunohistochemical demonstration of transferrin receptor 1 and 2 in human hepatocellular carcinoma tissue.

Polymorphisms of the TRF2 gene may be associated with age-related macular degeneration occurrence, either directly or by modulation of risk factors.
Title: Variability of the transferrin receptor 2 gene in AMD.

The following TFR2 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the TFR2 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

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***CloneID RefSeq Accession Definition **Vector *Turnaround time Price (USD) Select
OHu18638 NM_003227.3
Latest version!
Homo sapiens transferrin receptor 2 (TFR2), transcript variant 1, mRNA. pcDNA3.1+/C-(K)DYK or customized vector
in pcDNA3.1+/C-(K)DYK
$189.50-$265.30
$379.00
OHu18638 XM_017012573.1
Latest version!
Homo sapiens transferrin receptor 2 (TFR2), transcript variant X2, mRNA. pcDNA3.1+/C-(K)DYK or customized vector
in pcDNA3.1+/C-(K)DYK
$189.50-$265.30
$379.00
OHu18638 XM_005250553.4
Latest version!
Homo sapiens transferrin receptor 2 (TFR2), transcript variant X1, mRNA. pcDNA3.1+/C-(K)DYK or customized vector
in pcDNA3.1+/C-(K)DYK
$189.50-$265.30
$379.00
OHu16938 NM_001206855.1
Latest version!
Homo sapiens transferrin receptor 2 (TFR2), transcript variant 2, mRNA. pcDNA3.1+/C-(K)DYK or customized vector 7-9 $307.30
$439.00
View Old Accession Versions >>
OHu18638 XM_005250553.3 Homo sapiens transferrin receptor 2 (TFR2), transcript variant X1, mRNA. pcDNA3.1+/C-(K)DYK or customized vector
in pcDNA3.1+/C-(K)DYK
$189.50-$265.30
$379.00
Hide Old Accession Versions >>

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.


CloneID OHu18638
Clone ID Related Accession (Same CDS sequence) XM_005250553.4 , XM_005250553.3 , XM_017012573.1 , NM_003227.3
Accession Version NM_003227.3 Latest version! Documents for ORF clone product in dufault vector
Sequence Information ORF Nucleotide Sequence (Length: 2406bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags COA
ORF Insert Method CloneEZ® Seamless cloning technology
Insert Structure linear
Update Date 2017-05-06
Organism Homo sapiens(Human)
Product transferrin receptor protein 2 isoform 1
Comment REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from DR004213.1, AF067864.1 and BI917390.1. This sequence is a reference standard in the RefSeqGene project. On Jul 7, 2006 this sequence version replaced NM_003227.2. Transcript Variant: This variant (1) encodes the longer isoform (1, also known as alpha). Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AF067864.1, BC142630.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN04284274 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: full length.

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
1501
1561
1621
1681
1741
1801
1861
1921
1981
2041
2101
2161
2221
2281
2341
2401
ATGGAGCGGC TTTGGGGTCT ATTCCAGAGA GCGCAACAAC TGTCCCCAAG ATCCTCTCAG 
ACCGTCTACC AGCGTGTGGA AGGCCCCCGG AAAGGGCACC TGGAGGAGGA AGAGGAAGAC
GGGGAGGAGG GGGCGGAGAC ATTGGCCCAC TTCTGCCCCA TGGAGCTGAG GGGCCCTGAG
CCCCTGGGCT CTAGACCCAG GCAGCCAAAC CTCATTCCCT GGGCGGCAGC AGGACGGAGG
GCTGCCCCCT ACCTGGTCCT GACGGCCCTG CTGATCTTCA CTGGGGCCTT CCTACTGGGC
TACGTCGCCT TCCGAGGGTC CTGCCAGGCG TGCGGAGACT CTGTGTTGGT GGTCAGTGAG
GATGTCAACT ATGAGCCTGA CCTGGATTTC CACCAGGGCA GACTCTACTG GAGCGACCTC
CAGGCCATGT TCCTGCAGTT CCTGGGGGAG GGGCGCCTGG AGGACACCAT CAGGCAAACC
AGCCTTCGGG AACGGGTGGC AGGCTCGGCC GGGATGGCCG CTCTGACTCA GGACATTCGC
GCGGCGCTCT CCCGCCAGAA GCTGGACCAC GTGTGGACCG ACACGCACTA CGTGGGGCTG
CAATTCCCGG ATCCGGCTCA CCCCAACACC CTGCACTGGG TCGATGAGGC CGGGAAGGTC
GGAGAGCAGC TGCCGCTGGA GGACCCTGAC GTCTACTGCC CCTACAGCGC CATCGGCAAC
GTCACGGGAG AGCTGGTGTA CGCCCACTAC GGGCGGCCCG AAGACCTGCA GGACCTGCGG
GCCAGGGGCG TGGATCCAGT GGGCCGCCTG CTGCTGGTGC GCGTGGGGGT GATCAGCTTC
GCCCAGAAGG TGACCAATGC TCAGGACTTC GGGGCTCAAG GAGTGCTCAT ATACCCAGAG
CCAGCGGACT TCTCCCAGGA CCCACCCAAG CCAAGCCTGT CCAGCCAGCA GGCAGTGTAT
GGACATGTGC ACCTGGGAAC TGGAGACCCC TACACACCTG GCTTCCCTTC CTTCAATCAA
ACCCAGTTCC CTCCAGTTGC ATCATCAGGC CTTCCCAGCA TCCCAGCCCA GCCCATCAGT
GCAGACATTG CCTCCCGCCT GCTGAGGAAG CTCAAAGGCC CTGTGGCCCC CCAAGAATGG
CAGGGGAGCC TCCTAGGCTC CCCTTATCAC CTGGGCCCCG GGCCACGACT GCGGCTAGTG
GTCAACAATC ACAGGACCTC CACCCCCATC AACAACATCT TCGGCTGCAT CGAAGGCCGC
TCAGAGCCAG ATCACTACGT TGTCATCGGG GCCCAGAGGG ATGCATGGGG CCCAGGAGCA
GCTAAATCCG CTGTGGGGAC GGCTATACTC CTGGAGCTGG TGCGGACCTT TTCCTCCATG
GTGAGCAACG GCTTCCGGCC CCGCAGAAGT CTCCTCTTCA TCAGCTGGGA CGGTGGTGAC
TTTGGAAGCG TGGGCTCCAC GGAGTGGCTA GAGGGCTACC TCAGCGTGCT GCACCTCAAA
GCCGTAGTGT ACGTGAGCCT GGACAACGCA GTGCTGGGGG ATGACAAGTT TCATGCCAAG
ACCAGCCCCC TTCTGACAAG TCTCATTGAG AGTGTCCTGA AGCAGGTGGA TTCTCCCAAC
CACAGTGGGC AGACTCTCTA TGAACAGGTG GTGTTCACCA ATCCCAGCTG GGATGCTGAG
GTGATCCGGC CCCTACCCAT GGACAGCAGT GCCTATTCCT TCACGGCCTT TGTGGGAGTC
CCTGCCGTCG AGTTCTCCTT TATGGAGGAC GACCAGGCCT ACCCATTCCT GCACACAAAG
GAGGACACTT ATGAGAACCT GCATAAGGTG CTGCAAGGCC GCCTGCCCGC CGTGGCCCAG
GCCGTGGCCC AGCTCGCAGG GCAGCTCCTC ATCCGGCTCA GCCACGATCG CCTGCTGCCC
CTCGACTTCG GCCGCTACGG GGACGTCGTC CTCAGGCACA TCGGGAACCT CAACGAGTTC
TCTGGGGACC TCAAGGCCCG CGGGCTGACC CTGCAGTGGG TGTACTCGGC GCGGGGGGAC
TACATCCGGG CGGCGGAAAA GCTGCGGCAG GAGATCTACA GCTCGGAGGA GAGAGACGAG
CGACTGACAC GCATGTACAA CGTGCGCATA ATGCGGGTGG AGTTCTACTT CCTTTCCCAG
TACGTGTCGC CAGCCGACTC CCCGTTCCGC CACATCTTCA TGGGCCGTGG AGACCACACG
CTGGGCGCCC TGCTGGACCA CCTGCGGCTG CTGCGCTCCA ACAGCTCCGG GACCCCCGGG
GCCACCTCCT CCACTGGCTT CCAGGAGAGC CGTTTCCGGC GTCAGCTAGC CCTGCTCACC
TGGACGCTGC AAGGGGCAGC CAATGCGCTT AGCGGGGATG TCTGGAACAT TGATAACAAC
TTCTGA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq NP_003218.2
CDS42..2447
Misc Feature(1)108..119
Misc Feature(2)291..353
Misc Feature(3)order(363..365,372..374)
Misc Feature(4)672..1244
Misc Feature(5)order(948..950,990..1001,1005..1007,1017..1028,1035..1037,1041..1049)
Misc Feature(6)order(1020..1022,1038..1040)
Misc Feature(7)order(1035..1037,1044..1046)
Misc Feature(8)order(1047..1049,1053..1055,1065..1070)
Misc Feature(9)1266..1967
Misc Feature(10)order(1287..1289,1293..1295,1302..1304,1308..1313,1317..1319,1449..1451,1455..1457,1506..1508,1515..1541)
Misc Feature(11)2061..2414
Exon (1)1..74
Exon (2)75..327
Exon (3)328..514
Exon (4)515..655
Exon (5)656..767
Exon (6)768..890
Exon (7)891..1007
Exon (8)1008..1147
Exon (9)1148..1311
Exon (10)1312..1431
Exon (11)1432..1514
Exon (12)1515..1578
Exon (13)1579..1646
Exon (14)1647..1723
Exon (15)1724..1808
Exon (16)1809..2036
Exon (17)2037..2177
Exon (18)2178..2888
Translation

Target ORF information:

RefSeq Version NM_003227.3
Organism Homo sapiens(Human)
Definition Homo sapiens transferrin receptor 2 (TFR2), transcript variant 1, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
NM_003227.3

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
1501
1561
1621
1681
1741
1801
1861
1921
1981
2041
2101
2161
2221
2281
2341
2401
ATGGAGCGGC TTTGGGGTCT ATTCCAGAGA GCGCAACAAC TGTCCCCAAG ATCCTCTCAG 
ACCGTCTACC AGCGTGTGGA AGGCCCCCGG AAAGGGCACC TGGAGGAGGA AGAGGAAGAC
GGGGAGGAGG GGGCGGAGAC ATTGGCCCAC TTCTGCCCCA TGGAGCTGAG GGGCCCTGAG
CCCCTGGGCT CTAGACCCAG GCAGCCAAAC CTCATTCCCT GGGCGGCAGC AGGACGGAGG
GCTGCCCCCT ACCTGGTCCT GACGGCCCTG CTGATCTTCA CTGGGGCCTT CCTACTGGGC
TACGTCGCCT TCCGAGGGTC CTGCCAGGCG TGCGGAGACT CTGTGTTGGT GGTCAGTGAG
GATGTCAACT ATGAGCCTGA CCTGGATTTC CACCAGGGCA GACTCTACTG GAGCGACCTC
CAGGCCATGT TCCTGCAGTT CCTGGGGGAG GGGCGCCTGG AGGACACCAT CAGGCAAACC
AGCCTTCGGG AACGGGTGGC AGGCTCGGCC GGGATGGCCG CTCTGACTCA GGACATTCGC
GCGGCGCTCT CCCGCCAGAA GCTGGACCAC GTGTGGACCG ACACGCACTA CGTGGGGCTG
CAATTCCCGG ATCCGGCTCA CCCCAACACC CTGCACTGGG TCGATGAGGC CGGGAAGGTC
GGAGAGCAGC TGCCGCTGGA GGACCCTGAC GTCTACTGCC CCTACAGCGC CATCGGCAAC
GTCACGGGAG AGCTGGTGTA CGCCCACTAC GGGCGGCCCG AAGACCTGCA GGACCTGCGG
GCCAGGGGCG TGGATCCAGT GGGCCGCCTG CTGCTGGTGC GCGTGGGGGT GATCAGCTTC
GCCCAGAAGG TGACCAATGC TCAGGACTTC GGGGCTCAAG GAGTGCTCAT ATACCCAGAG
CCAGCGGACT TCTCCCAGGA CCCACCCAAG CCAAGCCTGT CCAGCCAGCA GGCAGTGTAT
GGACATGTGC ACCTGGGAAC TGGAGACCCC TACACACCTG GCTTCCCTTC CTTCAATCAA
ACCCAGTTCC CTCCAGTTGC ATCATCAGGC CTTCCCAGCA TCCCAGCCCA GCCCATCAGT
GCAGACATTG CCTCCCGCCT GCTGAGGAAG CTCAAAGGCC CTGTGGCCCC CCAAGAATGG
CAGGGGAGCC TCCTAGGCTC CCCTTATCAC CTGGGCCCCG GGCCACGACT GCGGCTAGTG
GTCAACAATC ACAGGACCTC CACCCCCATC AACAACATCT TCGGCTGCAT CGAAGGCCGC
TCAGAGCCAG ATCACTACGT TGTCATCGGG GCCCAGAGGG ATGCATGGGG CCCAGGAGCA
GCTAAATCCG CTGTGGGGAC GGCTATACTC CTGGAGCTGG TGCGGACCTT TTCCTCCATG
GTGAGCAACG GCTTCCGGCC CCGCAGAAGT CTCCTCTTCA TCAGCTGGGA CGGTGGTGAC
TTTGGAAGCG TGGGCTCCAC GGAGTGGCTA GAGGGCTACC TCAGCGTGCT GCACCTCAAA
GCCGTAGTGT ACGTGAGCCT GGACAACGCA GTGCTGGGGG ATGACAAGTT TCATGCCAAG
ACCAGCCCCC TTCTGACAAG TCTCATTGAG AGTGTCCTGA AGCAGGTGGA TTCTCCCAAC
CACAGTGGGC AGACTCTCTA TGAACAGGTG GTGTTCACCA ATCCCAGCTG GGATGCTGAG
GTGATCCGGC CCCTACCCAT GGACAGCAGT GCCTATTCCT TCACGGCCTT TGTGGGAGTC
CCTGCCGTCG AGTTCTCCTT TATGGAGGAC GACCAGGCCT ACCCATTCCT GCACACAAAG
GAGGACACTT ATGAGAACCT GCATAAGGTG CTGCAAGGCC GCCTGCCCGC CGTGGCCCAG
GCCGTGGCCC AGCTCGCAGG GCAGCTCCTC ATCCGGCTCA GCCACGATCG CCTGCTGCCC
CTCGACTTCG GCCGCTACGG GGACGTCGTC CTCAGGCACA TCGGGAACCT CAACGAGTTC
TCTGGGGACC TCAAGGCCCG CGGGCTGACC CTGCAGTGGG TGTACTCGGC GCGGGGGGAC
TACATCCGGG CGGCGGAAAA GCTGCGGCAG GAGATCTACA GCTCGGAGGA GAGAGACGAG
CGACTGACAC GCATGTACAA CGTGCGCATA ATGCGGGTGG AGTTCTACTT CCTTTCCCAG
TACGTGTCGC CAGCCGACTC CCCGTTCCGC CACATCTTCA TGGGCCGTGG AGACCACACG
CTGGGCGCCC TGCTGGACCA CCTGCGGCTG CTGCGCTCCA ACAGCTCCGG GACCCCCGGG
GCCACCTCCT CCACTGGCTT CCAGGAGAGC CGTTTCCGGC GTCAGCTAGC CCTGCTCACC
TGGACGCTGC AAGGGGCAGC CAATGCGCTT AGCGGGGATG TCTGGAACAT TGATAACAAC
TTCTGA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OHu18638
Clone ID Related Accession (Same CDS sequence) XM_005250553.4 , XM_005250553.3 , XM_017012573.1 , NM_003227.3
Accession Version XM_005250553.4 Latest version! Documents for ORF clone product in dufault vector
Sequence Information ORF Nucleotide Sequence (Length: 2406bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags COA
ORF Insert Method CloneEZ® Seamless cloning technology
Insert Structure linear
Update Date 2016-06-06
Organism Homo sapiens(Human)
Product transferrin receptor protein 2 isoform X1
Comment MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000007.14) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 6, 2016 this sequence version replaced XM_005250553.3. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Homo sapiens Annotation Release 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
1501
1561
1621
1681
1741
1801
1861
1921
1981
2041
2101
2161
2221
2281
2341
2401
ATGGAGCGGC TTTGGGGTCT ATTCCAGAGA GCGCAACAAC TGTCCCCAAG ATCCTCTCAG 
ACCGTCTACC AGCGTGTGGA AGGCCCCCGG AAAGGGCACC TGGAGGAGGA AGAGGAAGAC
GGGGAGGAGG GGGCGGAGAC ATTGGCCCAC TTCTGCCCCA TGGAGCTGAG GGGCCCTGAG
CCCCTGGGCT CTAGACCCAG GCAGCCAAAC CTCATTCCCT GGGCGGCAGC AGGACGGAGG
GCTGCCCCCT ACCTGGTCCT GACGGCCCTG CTGATCTTCA CTGGGGCCTT CCTACTGGGC
TACGTCGCCT TCCGAGGGTC CTGCCAGGCG TGCGGAGACT CTGTGTTGGT GGTCAGTGAG
GATGTCAACT ATGAGCCTGA CCTGGATTTC CACCAGGGCA GACTCTACTG GAGCGACCTC
CAGGCCATGT TCCTGCAGTT CCTGGGGGAG GGGCGCCTGG AGGACACCAT CAGGCAAACC
AGCCTTCGGG AACGGGTGGC AGGCTCGGCC GGGATGGCCG CTCTGACTCA GGACATTCGC
GCGGCGCTCT CCCGCCAGAA GCTGGACCAC GTGTGGACCG ACACGCACTA CGTGGGGCTG
CAATTCCCGG ATCCGGCTCA CCCCAACACC CTGCACTGGG TCGATGAGGC CGGGAAGGTC
GGAGAGCAGC TGCCGCTGGA GGACCCTGAC GTCTACTGCC CCTACAGCGC CATCGGCAAC
GTCACGGGAG AGCTGGTGTA CGCCCACTAC GGGCGGCCCG AAGACCTGCA GGACCTGCGG
GCCAGGGGCG TGGATCCAGT GGGCCGCCTG CTGCTGGTGC GCGTGGGGGT GATCAGCTTC
GCCCAGAAGG TGACCAATGC TCAGGACTTC GGGGCTCAAG GAGTGCTCAT ATACCCAGAG
CCAGCGGACT TCTCCCAGGA CCCACCCAAG CCAAGCCTGT CCAGCCAGCA GGCAGTGTAT
GGACATGTGC ACCTGGGAAC TGGAGACCCC TACACACCTG GCTTCCCTTC CTTCAATCAA
ACCCAGTTCC CTCCAGTTGC ATCATCAGGC CTTCCCAGCA TCCCAGCCCA GCCCATCAGT
GCAGACATTG CCTCCCGCCT GCTGAGGAAG CTCAAAGGCC CTGTGGCCCC CCAAGAATGG
CAGGGGAGCC TCCTAGGCTC CCCTTATCAC CTGGGCCCCG GGCCACGACT GCGGCTAGTG
GTCAACAATC ACAGGACCTC CACCCCCATC AACAACATCT TCGGCTGCAT CGAAGGCCGC
TCAGAGCCAG ATCACTACGT TGTCATCGGG GCCCAGAGGG ATGCATGGGG CCCAGGAGCA
GCTAAATCCG CTGTGGGGAC GGCTATACTC CTGGAGCTGG TGCGGACCTT TTCCTCCATG
GTGAGCAACG GCTTCCGGCC CCGCAGAAGT CTCCTCTTCA TCAGCTGGGA CGGTGGTGAC
TTTGGAAGCG TGGGCTCCAC GGAGTGGCTA GAGGGCTACC TCAGCGTGCT GCACCTCAAA
GCCGTAGTGT ACGTGAGCCT GGACAACGCA GTGCTGGGGG ATGACAAGTT TCATGCCAAG
ACCAGCCCCC TTCTGACAAG TCTCATTGAG AGTGTCCTGA AGCAGGTGGA TTCTCCCAAC
CACAGTGGGC AGACTCTCTA TGAACAGGTG GTGTTCACCA ATCCCAGCTG GGATGCTGAG
GTGATCCGGC CCCTACCCAT GGACAGCAGT GCCTATTCCT TCACGGCCTT TGTGGGAGTC
CCTGCCGTCG AGTTCTCCTT TATGGAGGAC GACCAGGCCT ACCCATTCCT GCACACAAAG
GAGGACACTT ATGAGAACCT GCATAAGGTG CTGCAAGGCC GCCTGCCCGC CGTGGCCCAG
GCCGTGGCCC AGCTCGCAGG GCAGCTCCTC ATCCGGCTCA GCCACGATCG CCTGCTGCCC
CTCGACTTCG GCCGCTACGG GGACGTCGTC CTCAGGCACA TCGGGAACCT CAACGAGTTC
TCTGGGGACC TCAAGGCCCG CGGGCTGACC CTGCAGTGGG TGTACTCGGC GCGGGGGGAC
TACATCCGGG CGGCGGAAAA GCTGCGGCAG GAGATCTACA GCTCGGAGGA GAGAGACGAG
CGACTGACAC GCATGTACAA CGTGCGCATA ATGCGGGTGG AGTTCTACTT CCTTTCCCAG
TACGTGTCGC CAGCCGACTC CCCGTTCCGC CACATCTTCA TGGGCCGTGG AGACCACACG
CTGGGCGCCC TGCTGGACCA CCTGCGGCTG CTGCGCTCCA ACAGCTCCGG GACCCCCGGG
GCCACCTCCT CCACTGGCTT CCAGGAGAGC CGTTTCCGGC GTCAGCTAGC CCTGCTCACC
TGGACGCTGC AAGGGGCAGC CAATGCGCTT AGCGGGGATG TCTGGAACAT TGATAACAAC
TTCTGA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq XP_005250610.1
CDS348..2753
Misc Feature(1)978..1550
Misc Feature(2)order(1254..1256,1296..1307,1311..1313,1323..1334,1341..1343,1347..1355)
Misc Feature(3)order(1326..1328,1344..1346)
Misc Feature(4)order(1341..1343,1350..1352)
Misc Feature(5)order(1353..1355,1359..1361,1371..1376)
Misc Feature(6)1572..2273
Misc Feature(7)order(1593..1595,1599..1601,1608..1610,1614..1619,1623..1625,1755..1757,1761..1763,1812..1814,1821..1847)
Misc Feature(8)2367..2720
Translation

Target ORF information:

RefSeq Version XM_005250553.4
Organism Homo sapiens(Human)
Definition Homo sapiens transferrin receptor 2 (TFR2), transcript variant X1, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
XM_005250553.4

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
1501
1561
1621
1681
1741
1801
1861
1921
1981
2041
2101
2161
2221
2281
2341
2401
ATGGAGCGGC TTTGGGGTCT ATTCCAGAGA GCGCAACAAC TGTCCCCAAG ATCCTCTCAG 
ACCGTCTACC AGCGTGTGGA AGGCCCCCGG AAAGGGCACC TGGAGGAGGA AGAGGAAGAC
GGGGAGGAGG GGGCGGAGAC ATTGGCCCAC TTCTGCCCCA TGGAGCTGAG GGGCCCTGAG
CCCCTGGGCT CTAGACCCAG GCAGCCAAAC CTCATTCCCT GGGCGGCAGC AGGACGGAGG
GCTGCCCCCT ACCTGGTCCT GACGGCCCTG CTGATCTTCA CTGGGGCCTT CCTACTGGGC
TACGTCGCCT TCCGAGGGTC CTGCCAGGCG TGCGGAGACT CTGTGTTGGT GGTCAGTGAG
GATGTCAACT ATGAGCCTGA CCTGGATTTC CACCAGGGCA GACTCTACTG GAGCGACCTC
CAGGCCATGT TCCTGCAGTT CCTGGGGGAG GGGCGCCTGG AGGACACCAT CAGGCAAACC
AGCCTTCGGG AACGGGTGGC AGGCTCGGCC GGGATGGCCG CTCTGACTCA GGACATTCGC
GCGGCGCTCT CCCGCCAGAA GCTGGACCAC GTGTGGACCG ACACGCACTA CGTGGGGCTG
CAATTCCCGG ATCCGGCTCA CCCCAACACC CTGCACTGGG TCGATGAGGC CGGGAAGGTC
GGAGAGCAGC TGCCGCTGGA GGACCCTGAC GTCTACTGCC CCTACAGCGC CATCGGCAAC
GTCACGGGAG AGCTGGTGTA CGCCCACTAC GGGCGGCCCG AAGACCTGCA GGACCTGCGG
GCCAGGGGCG TGGATCCAGT GGGCCGCCTG CTGCTGGTGC GCGTGGGGGT GATCAGCTTC
GCCCAGAAGG TGACCAATGC TCAGGACTTC GGGGCTCAAG GAGTGCTCAT ATACCCAGAG
CCAGCGGACT TCTCCCAGGA CCCACCCAAG CCAAGCCTGT CCAGCCAGCA GGCAGTGTAT
GGACATGTGC ACCTGGGAAC TGGAGACCCC TACACACCTG GCTTCCCTTC CTTCAATCAA
ACCCAGTTCC CTCCAGTTGC ATCATCAGGC CTTCCCAGCA TCCCAGCCCA GCCCATCAGT
GCAGACATTG CCTCCCGCCT GCTGAGGAAG CTCAAAGGCC CTGTGGCCCC CCAAGAATGG
CAGGGGAGCC TCCTAGGCTC CCCTTATCAC CTGGGCCCCG GGCCACGACT GCGGCTAGTG
GTCAACAATC ACAGGACCTC CACCCCCATC AACAACATCT TCGGCTGCAT CGAAGGCCGC
TCAGAGCCAG ATCACTACGT TGTCATCGGG GCCCAGAGGG ATGCATGGGG CCCAGGAGCA
GCTAAATCCG CTGTGGGGAC GGCTATACTC CTGGAGCTGG TGCGGACCTT TTCCTCCATG
GTGAGCAACG GCTTCCGGCC CCGCAGAAGT CTCCTCTTCA TCAGCTGGGA CGGTGGTGAC
TTTGGAAGCG TGGGCTCCAC GGAGTGGCTA GAGGGCTACC TCAGCGTGCT GCACCTCAAA
GCCGTAGTGT ACGTGAGCCT GGACAACGCA GTGCTGGGGG ATGACAAGTT TCATGCCAAG
ACCAGCCCCC TTCTGACAAG TCTCATTGAG AGTGTCCTGA AGCAGGTGGA TTCTCCCAAC
CACAGTGGGC AGACTCTCTA TGAACAGGTG GTGTTCACCA ATCCCAGCTG GGATGCTGAG
GTGATCCGGC CCCTACCCAT GGACAGCAGT GCCTATTCCT TCACGGCCTT TGTGGGAGTC
CCTGCCGTCG AGTTCTCCTT TATGGAGGAC GACCAGGCCT ACCCATTCCT GCACACAAAG
GAGGACACTT ATGAGAACCT GCATAAGGTG CTGCAAGGCC GCCTGCCCGC CGTGGCCCAG
GCCGTGGCCC AGCTCGCAGG GCAGCTCCTC ATCCGGCTCA GCCACGATCG CCTGCTGCCC
CTCGACTTCG GCCGCTACGG GGACGTCGTC CTCAGGCACA TCGGGAACCT CAACGAGTTC
TCTGGGGACC TCAAGGCCCG CGGGCTGACC CTGCAGTGGG TGTACTCGGC GCGGGGGGAC
TACATCCGGG CGGCGGAAAA GCTGCGGCAG GAGATCTACA GCTCGGAGGA GAGAGACGAG
CGACTGACAC GCATGTACAA CGTGCGCATA ATGCGGGTGG AGTTCTACTT CCTTTCCCAG
TACGTGTCGC CAGCCGACTC CCCGTTCCGC CACATCTTCA TGGGCCGTGG AGACCACACG
CTGGGCGCCC TGCTGGACCA CCTGCGGCTG CTGCGCTCCA ACAGCTCCGG GACCCCCGGG
GCCACCTCCT CCACTGGCTT CCAGGAGAGC CGTTTCCGGC GTCAGCTAGC CCTGCTCACC
TGGACGCTGC AAGGGGCAGC CAATGCGCTT AGCGGGGATG TCTGGAACAT TGATAACAAC
TTCTGA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OHu18638
Clone ID Related Accession (Same CDS sequence) XM_005250553.4 , XM_005250553.3 , XM_017012573.1 , NM_003227.3
Accession Version XM_005250553.3 Documents for ORF clone product in dufault vector
Sequence Information ORF Nucleotide Sequence (Length: 2406bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags COA
ORF Insert Method CloneEZ® Seamless cloning technology
Insert Structure linear
Update Date 2015-03-12
Organism Homo sapiens(Human)
Product transferrin receptor protein 2 isoform X1
Comment

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
1501
1561
1621
1681
1741
1801
1861
1921
1981
2041
2101
2161
2221
2281
2341
2401
ATGGAGCGGC TTTGGGGTCT ATTCCAGAGA GCGCAACAAC TGTCCCCAAG ATCCTCTCAG 
ACCGTCTACC AGCGTGTGGA AGGCCCCCGG AAAGGGCACC TGGAGGAGGA AGAGGAAGAC
GGGGAGGAGG GGGCGGAGAC ATTGGCCCAC TTCTGCCCCA TGGAGCTGAG GGGCCCTGAG
CCCCTGGGCT CTAGACCCAG GCAGCCAAAC CTCATTCCCT GGGCGGCAGC AGGACGGAGG
GCTGCCCCCT ACCTGGTCCT GACGGCCCTG CTGATCTTCA CTGGGGCCTT CCTACTGGGC
TACGTCGCCT TCCGAGGGTC CTGCCAGGCG TGCGGAGACT CTGTGTTGGT GGTCAGTGAG
GATGTCAACT ATGAGCCTGA CCTGGATTTC CACCAGGGCA GACTCTACTG GAGCGACCTC
CAGGCCATGT TCCTGCAGTT CCTGGGGGAG GGGCGCCTGG AGGACACCAT CAGGCAAACC
AGCCTTCGGG AACGGGTGGC AGGCTCGGCC GGGATGGCCG CTCTGACTCA GGACATTCGC
GCGGCGCTCT CCCGCCAGAA GCTGGACCAC GTGTGGACCG ACACGCACTA CGTGGGGCTG
CAATTCCCGG ATCCGGCTCA CCCCAACACC CTGCACTGGG TCGATGAGGC CGGGAAGGTC
GGAGAGCAGC TGCCGCTGGA GGACCCTGAC GTCTACTGCC CCTACAGCGC CATCGGCAAC
GTCACGGGAG AGCTGGTGTA CGCCCACTAC GGGCGGCCCG AAGACCTGCA GGACCTGCGG
GCCAGGGGCG TGGATCCAGT GGGCCGCCTG CTGCTGGTGC GCGTGGGGGT GATCAGCTTC
GCCCAGAAGG TGACCAATGC TCAGGACTTC GGGGCTCAAG GAGTGCTCAT ATACCCAGAG
CCAGCGGACT TCTCCCAGGA CCCACCCAAG CCAAGCCTGT CCAGCCAGCA GGCAGTGTAT
GGACATGTGC ACCTGGGAAC TGGAGACCCC TACACACCTG GCTTCCCTTC CTTCAATCAA
ACCCAGTTCC CTCCAGTTGC ATCATCAGGC CTTCCCAGCA TCCCAGCCCA GCCCATCAGT
GCAGACATTG CCTCCCGCCT GCTGAGGAAG CTCAAAGGCC CTGTGGCCCC CCAAGAATGG
CAGGGGAGCC TCCTAGGCTC CCCTTATCAC CTGGGCCCCG GGCCACGACT GCGGCTAGTG
GTCAACAATC ACAGGACCTC CACCCCCATC AACAACATCT TCGGCTGCAT CGAAGGCCGC
TCAGAGCCAG ATCACTACGT TGTCATCGGG GCCCAGAGGG ATGCATGGGG CCCAGGAGCA
GCTAAATCCG CTGTGGGGAC GGCTATACTC CTGGAGCTGG TGCGGACCTT TTCCTCCATG
GTGAGCAACG GCTTCCGGCC CCGCAGAAGT CTCCTCTTCA TCAGCTGGGA CGGTGGTGAC
TTTGGAAGCG TGGGCTCCAC GGAGTGGCTA GAGGGCTACC TCAGCGTGCT GCACCTCAAA
GCCGTAGTGT ACGTGAGCCT GGACAACGCA GTGCTGGGGG ATGACAAGTT TCATGCCAAG
ACCAGCCCCC TTCTGACAAG TCTCATTGAG AGTGTCCTGA AGCAGGTGGA TTCTCCCAAC
CACAGTGGGC AGACTCTCTA TGAACAGGTG GTGTTCACCA ATCCCAGCTG GGATGCTGAG
GTGATCCGGC CCCTACCCAT GGACAGCAGT GCCTATTCCT TCACGGCCTT TGTGGGAGTC
CCTGCCGTCG AGTTCTCCTT TATGGAGGAC GACCAGGCCT ACCCATTCCT GCACACAAAG
GAGGACACTT ATGAGAACCT GCATAAGGTG CTGCAAGGCC GCCTGCCCGC CGTGGCCCAG
GCCGTGGCCC AGCTCGCAGG GCAGCTCCTC ATCCGGCTCA GCCACGATCG CCTGCTGCCC
CTCGACTTCG GCCGCTACGG GGACGTCGTC CTCAGGCACA TCGGGAACCT CAACGAGTTC
TCTGGGGACC TCAAGGCCCG CGGGCTGACC CTGCAGTGGG TGTACTCGGC GCGGGGGGAC
TACATCCGGG CGGCGGAAAA GCTGCGGCAG GAGATCTACA GCTCGGAGGA GAGAGACGAG
CGACTGACAC GCATGTACAA CGTGCGCATA ATGCGGGTGG AGTTCTACTT CCTTTCCCAG
TACGTGTCGC CAGCCGACTC CCCGTTCCGC CACATCTTCA TGGGCCGTGG AGACCACACG
CTGGGCGCCC TGCTGGACCA CCTGCGGCTG CTGCGCTCCA ACAGCTCCGG GACCCCCGGG
GCCACCTCCT CCACTGGCTT CCAGGAGAGC CGTTTCCGGC GTCAGCTAGC CCTGCTCACC
TGGACGCTGC AAGGGGCAGC CAATGCGCTT AGCGGGGATG TCTGGAACAT TGATAACAAC
TTCTGA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq XP_005250610.1
Translation

Target ORF information:

RefSeq Version XM_005250553.3
Organism Homo sapiens(Human)
Definition Homo sapiens transferrin receptor 2 (TFR2), transcript variant X1, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
XM_005250553.3

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
1501
1561
1621
1681
1741
1801
1861
1921
1981
2041
2101
2161
2221
2281
2341
2401
ATGGAGCGGC TTTGGGGTCT ATTCCAGAGA GCGCAACAAC TGTCCCCAAG ATCCTCTCAG 
ACCGTCTACC AGCGTGTGGA AGGCCCCCGG AAAGGGCACC TGGAGGAGGA AGAGGAAGAC
GGGGAGGAGG GGGCGGAGAC ATTGGCCCAC TTCTGCCCCA TGGAGCTGAG GGGCCCTGAG
CCCCTGGGCT CTAGACCCAG GCAGCCAAAC CTCATTCCCT GGGCGGCAGC AGGACGGAGG
GCTGCCCCCT ACCTGGTCCT GACGGCCCTG CTGATCTTCA CTGGGGCCTT CCTACTGGGC
TACGTCGCCT TCCGAGGGTC CTGCCAGGCG TGCGGAGACT CTGTGTTGGT GGTCAGTGAG
GATGTCAACT ATGAGCCTGA CCTGGATTTC CACCAGGGCA GACTCTACTG GAGCGACCTC
CAGGCCATGT TCCTGCAGTT CCTGGGGGAG GGGCGCCTGG AGGACACCAT CAGGCAAACC
AGCCTTCGGG AACGGGTGGC AGGCTCGGCC GGGATGGCCG CTCTGACTCA GGACATTCGC
GCGGCGCTCT CCCGCCAGAA GCTGGACCAC GTGTGGACCG ACACGCACTA CGTGGGGCTG
CAATTCCCGG ATCCGGCTCA CCCCAACACC CTGCACTGGG TCGATGAGGC CGGGAAGGTC
GGAGAGCAGC TGCCGCTGGA GGACCCTGAC GTCTACTGCC CCTACAGCGC CATCGGCAAC
GTCACGGGAG AGCTGGTGTA CGCCCACTAC GGGCGGCCCG AAGACCTGCA GGACCTGCGG
GCCAGGGGCG TGGATCCAGT GGGCCGCCTG CTGCTGGTGC GCGTGGGGGT GATCAGCTTC
GCCCAGAAGG TGACCAATGC TCAGGACTTC GGGGCTCAAG GAGTGCTCAT ATACCCAGAG
CCAGCGGACT TCTCCCAGGA CCCACCCAAG CCAAGCCTGT CCAGCCAGCA GGCAGTGTAT
GGACATGTGC ACCTGGGAAC TGGAGACCCC TACACACCTG GCTTCCCTTC CTTCAATCAA
ACCCAGTTCC CTCCAGTTGC ATCATCAGGC CTTCCCAGCA TCCCAGCCCA GCCCATCAGT
GCAGACATTG CCTCCCGCCT GCTGAGGAAG CTCAAAGGCC CTGTGGCCCC CCAAGAATGG
CAGGGGAGCC TCCTAGGCTC CCCTTATCAC CTGGGCCCCG GGCCACGACT GCGGCTAGTG
GTCAACAATC ACAGGACCTC CACCCCCATC AACAACATCT TCGGCTGCAT CGAAGGCCGC
TCAGAGCCAG ATCACTACGT TGTCATCGGG GCCCAGAGGG ATGCATGGGG CCCAGGAGCA
GCTAAATCCG CTGTGGGGAC GGCTATACTC CTGGAGCTGG TGCGGACCTT TTCCTCCATG
GTGAGCAACG GCTTCCGGCC CCGCAGAAGT CTCCTCTTCA TCAGCTGGGA CGGTGGTGAC
TTTGGAAGCG TGGGCTCCAC GGAGTGGCTA GAGGGCTACC TCAGCGTGCT GCACCTCAAA
GCCGTAGTGT ACGTGAGCCT GGACAACGCA GTGCTGGGGG ATGACAAGTT TCATGCCAAG
ACCAGCCCCC TTCTGACAAG TCTCATTGAG AGTGTCCTGA AGCAGGTGGA TTCTCCCAAC
CACAGTGGGC AGACTCTCTA TGAACAGGTG GTGTTCACCA ATCCCAGCTG GGATGCTGAG
GTGATCCGGC CCCTACCCAT GGACAGCAGT GCCTATTCCT TCACGGCCTT TGTGGGAGTC
CCTGCCGTCG AGTTCTCCTT TATGGAGGAC GACCAGGCCT ACCCATTCCT GCACACAAAG
GAGGACACTT ATGAGAACCT GCATAAGGTG CTGCAAGGCC GCCTGCCCGC CGTGGCCCAG
GCCGTGGCCC AGCTCGCAGG GCAGCTCCTC ATCCGGCTCA GCCACGATCG CCTGCTGCCC
CTCGACTTCG GCCGCTACGG GGACGTCGTC CTCAGGCACA TCGGGAACCT CAACGAGTTC
TCTGGGGACC TCAAGGCCCG CGGGCTGACC CTGCAGTGGG TGTACTCGGC GCGGGGGGAC
TACATCCGGG CGGCGGAAAA GCTGCGGCAG GAGATCTACA GCTCGGAGGA GAGAGACGAG
CGACTGACAC GCATGTACAA CGTGCGCATA ATGCGGGTGG AGTTCTACTT CCTTTCCCAG
TACGTGTCGC CAGCCGACTC CCCGTTCCGC CACATCTTCA TGGGCCGTGG AGACCACACG
CTGGGCGCCC TGCTGGACCA CCTGCGGCTG CTGCGCTCCA ACAGCTCCGG GACCCCCGGG
GCCACCTCCT CCACTGGCTT CCAGGAGAGC CGTTTCCGGC GTCAGCTAGC CCTGCTCACC
TGGACGCTGC AAGGGGCAGC CAATGCGCTT AGCGGGGATG TCTGGAACAT TGATAACAAC
TTCTGA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OHu18638
Clone ID Related Accession (Same CDS sequence) XM_005250553.4 , XM_005250553.3 , XM_017012573.1 , NM_003227.3
Accession Version XM_017012573.1 Latest version! Documents for ORF clone product in dufault vector
Sequence Information ORF Nucleotide Sequence (Length: 2406bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags COA
ORF Insert Method CloneEZ® Seamless cloning technology
Insert Structure linear
Update Date 2016-06-06
Organism Homo sapiens(Human)
Product transferrin receptor protein 2 isoform X1
Comment MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000007.14) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Homo sapiens Annotation Release 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
1501
1561
1621
1681
1741
1801
1861
1921
1981
2041
2101
2161
2221
2281
2341
2401
ATGGAGCGGC TTTGGGGTCT ATTCCAGAGA GCGCAACAAC TGTCCCCAAG ATCCTCTCAG 
ACCGTCTACC AGCGTGTGGA AGGCCCCCGG AAAGGGCACC TGGAGGAGGA AGAGGAAGAC
GGGGAGGAGG GGGCGGAGAC ATTGGCCCAC TTCTGCCCCA TGGAGCTGAG GGGCCCTGAG
CCCCTGGGCT CTAGACCCAG GCAGCCAAAC CTCATTCCCT GGGCGGCAGC AGGACGGAGG
GCTGCCCCCT ACCTGGTCCT GACGGCCCTG CTGATCTTCA CTGGGGCCTT CCTACTGGGC
TACGTCGCCT TCCGAGGGTC CTGCCAGGCG TGCGGAGACT CTGTGTTGGT GGTCAGTGAG
GATGTCAACT ATGAGCCTGA CCTGGATTTC CACCAGGGCA GACTCTACTG GAGCGACCTC
CAGGCCATGT TCCTGCAGTT CCTGGGGGAG GGGCGCCTGG AGGACACCAT CAGGCAAACC
AGCCTTCGGG AACGGGTGGC AGGCTCGGCC GGGATGGCCG CTCTGACTCA GGACATTCGC
GCGGCGCTCT CCCGCCAGAA GCTGGACCAC GTGTGGACCG ACACGCACTA CGTGGGGCTG
CAATTCCCGG ATCCGGCTCA CCCCAACACC CTGCACTGGG TCGATGAGGC CGGGAAGGTC
GGAGAGCAGC TGCCGCTGGA GGACCCTGAC GTCTACTGCC CCTACAGCGC CATCGGCAAC
GTCACGGGAG AGCTGGTGTA CGCCCACTAC GGGCGGCCCG AAGACCTGCA GGACCTGCGG
GCCAGGGGCG TGGATCCAGT GGGCCGCCTG CTGCTGGTGC GCGTGGGGGT GATCAGCTTC
GCCCAGAAGG TGACCAATGC TCAGGACTTC GGGGCTCAAG GAGTGCTCAT ATACCCAGAG
CCAGCGGACT TCTCCCAGGA CCCACCCAAG CCAAGCCTGT CCAGCCAGCA GGCAGTGTAT
GGACATGTGC ACCTGGGAAC TGGAGACCCC TACACACCTG GCTTCCCTTC CTTCAATCAA
ACCCAGTTCC CTCCAGTTGC ATCATCAGGC CTTCCCAGCA TCCCAGCCCA GCCCATCAGT
GCAGACATTG CCTCCCGCCT GCTGAGGAAG CTCAAAGGCC CTGTGGCCCC CCAAGAATGG
CAGGGGAGCC TCCTAGGCTC CCCTTATCAC CTGGGCCCCG GGCCACGACT GCGGCTAGTG
GTCAACAATC ACAGGACCTC CACCCCCATC AACAACATCT TCGGCTGCAT CGAAGGCCGC
TCAGAGCCAG ATCACTACGT TGTCATCGGG GCCCAGAGGG ATGCATGGGG CCCAGGAGCA
GCTAAATCCG CTGTGGGGAC GGCTATACTC CTGGAGCTGG TGCGGACCTT TTCCTCCATG
GTGAGCAACG GCTTCCGGCC CCGCAGAAGT CTCCTCTTCA TCAGCTGGGA CGGTGGTGAC
TTTGGAAGCG TGGGCTCCAC GGAGTGGCTA GAGGGCTACC TCAGCGTGCT GCACCTCAAA
GCCGTAGTGT ACGTGAGCCT GGACAACGCA GTGCTGGGGG ATGACAAGTT TCATGCCAAG
ACCAGCCCCC TTCTGACAAG TCTCATTGAG AGTGTCCTGA AGCAGGTGGA TTCTCCCAAC
CACAGTGGGC AGACTCTCTA TGAACAGGTG GTGTTCACCA ATCCCAGCTG GGATGCTGAG
GTGATCCGGC CCCTACCCAT GGACAGCAGT GCCTATTCCT TCACGGCCTT TGTGGGAGTC
CCTGCCGTCG AGTTCTCCTT TATGGAGGAC GACCAGGCCT ACCCATTCCT GCACACAAAG
GAGGACACTT ATGAGAACCT GCATAAGGTG CTGCAAGGCC GCCTGCCCGC CGTGGCCCAG
GCCGTGGCCC AGCTCGCAGG GCAGCTCCTC ATCCGGCTCA GCCACGATCG CCTGCTGCCC
CTCGACTTCG GCCGCTACGG GGACGTCGTC CTCAGGCACA TCGGGAACCT CAACGAGTTC
TCTGGGGACC TCAAGGCCCG CGGGCTGACC CTGCAGTGGG TGTACTCGGC GCGGGGGGAC
TACATCCGGG CGGCGGAAAA GCTGCGGCAG GAGATCTACA GCTCGGAGGA GAGAGACGAG
CGACTGACAC GCATGTACAA CGTGCGCATA ATGCGGGTGG AGTTCTACTT CCTTTCCCAG
TACGTGTCGC CAGCCGACTC CCCGTTCCGC CACATCTTCA TGGGCCGTGG AGACCACACG
CTGGGCGCCC TGCTGGACCA CCTGCGGCTG CTGCGCTCCA ACAGCTCCGG GACCCCCGGG
GCCACCTCCT CCACTGGCTT CCAGGAGAGC CGTTTCCGGC GTCAGCTAGC CCTGCTCACC
TGGACGCTGC AAGGGGCAGC CAATGCGCTT AGCGGGGATG TCTGGAACAT TGATAACAAC
TTCTGA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq XP_016868062.1
CDS150..2555
Misc Feature(1)780..1352
Misc Feature(2)order(1056..1058,1098..1109,1113..1115,1125..1136,1143..1145,1149..1157)
Misc Feature(3)order(1128..1130,1146..1148)
Misc Feature(4)order(1143..1145,1152..1154)
Misc Feature(5)order(1155..1157,1161..1163,1173..1178)
Misc Feature(6)1374..2075
Misc Feature(7)order(1395..1397,1401..1403,1410..1412,1416..1421,1425..1427,1557..1559,1563..1565,1614..1616,1623..1649)
Misc Feature(8)2169..2522
Translation

Target ORF information:

RefSeq Version XM_017012573.1
Organism Homo sapiens(Human)
Definition Homo sapiens transferrin receptor 2 (TFR2), transcript variant X2, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
XM_017012573.1

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
1501
1561
1621
1681
1741
1801
1861
1921
1981
2041
2101
2161
2221
2281
2341
2401
ATGGAGCGGC TTTGGGGTCT ATTCCAGAGA GCGCAACAAC TGTCCCCAAG ATCCTCTCAG 
ACCGTCTACC AGCGTGTGGA AGGCCCCCGG AAAGGGCACC TGGAGGAGGA AGAGGAAGAC
GGGGAGGAGG GGGCGGAGAC ATTGGCCCAC TTCTGCCCCA TGGAGCTGAG GGGCCCTGAG
CCCCTGGGCT CTAGACCCAG GCAGCCAAAC CTCATTCCCT GGGCGGCAGC AGGACGGAGG
GCTGCCCCCT ACCTGGTCCT GACGGCCCTG CTGATCTTCA CTGGGGCCTT CCTACTGGGC
TACGTCGCCT TCCGAGGGTC CTGCCAGGCG TGCGGAGACT CTGTGTTGGT GGTCAGTGAG
GATGTCAACT ATGAGCCTGA CCTGGATTTC CACCAGGGCA GACTCTACTG GAGCGACCTC
CAGGCCATGT TCCTGCAGTT CCTGGGGGAG GGGCGCCTGG AGGACACCAT CAGGCAAACC
AGCCTTCGGG AACGGGTGGC AGGCTCGGCC GGGATGGCCG CTCTGACTCA GGACATTCGC
GCGGCGCTCT CCCGCCAGAA GCTGGACCAC GTGTGGACCG ACACGCACTA CGTGGGGCTG
CAATTCCCGG ATCCGGCTCA CCCCAACACC CTGCACTGGG TCGATGAGGC CGGGAAGGTC
GGAGAGCAGC TGCCGCTGGA GGACCCTGAC GTCTACTGCC CCTACAGCGC CATCGGCAAC
GTCACGGGAG AGCTGGTGTA CGCCCACTAC GGGCGGCCCG AAGACCTGCA GGACCTGCGG
GCCAGGGGCG TGGATCCAGT GGGCCGCCTG CTGCTGGTGC GCGTGGGGGT GATCAGCTTC
GCCCAGAAGG TGACCAATGC TCAGGACTTC GGGGCTCAAG GAGTGCTCAT ATACCCAGAG
CCAGCGGACT TCTCCCAGGA CCCACCCAAG CCAAGCCTGT CCAGCCAGCA GGCAGTGTAT
GGACATGTGC ACCTGGGAAC TGGAGACCCC TACACACCTG GCTTCCCTTC CTTCAATCAA
ACCCAGTTCC CTCCAGTTGC ATCATCAGGC CTTCCCAGCA TCCCAGCCCA GCCCATCAGT
GCAGACATTG CCTCCCGCCT GCTGAGGAAG CTCAAAGGCC CTGTGGCCCC CCAAGAATGG
CAGGGGAGCC TCCTAGGCTC CCCTTATCAC CTGGGCCCCG GGCCACGACT GCGGCTAGTG
GTCAACAATC ACAGGACCTC CACCCCCATC AACAACATCT TCGGCTGCAT CGAAGGCCGC
TCAGAGCCAG ATCACTACGT TGTCATCGGG GCCCAGAGGG ATGCATGGGG CCCAGGAGCA
GCTAAATCCG CTGTGGGGAC GGCTATACTC CTGGAGCTGG TGCGGACCTT TTCCTCCATG
GTGAGCAACG GCTTCCGGCC CCGCAGAAGT CTCCTCTTCA TCAGCTGGGA CGGTGGTGAC
TTTGGAAGCG TGGGCTCCAC GGAGTGGCTA GAGGGCTACC TCAGCGTGCT GCACCTCAAA
GCCGTAGTGT ACGTGAGCCT GGACAACGCA GTGCTGGGGG ATGACAAGTT TCATGCCAAG
ACCAGCCCCC TTCTGACAAG TCTCATTGAG AGTGTCCTGA AGCAGGTGGA TTCTCCCAAC
CACAGTGGGC AGACTCTCTA TGAACAGGTG GTGTTCACCA ATCCCAGCTG GGATGCTGAG
GTGATCCGGC CCCTACCCAT GGACAGCAGT GCCTATTCCT TCACGGCCTT TGTGGGAGTC
CCTGCCGTCG AGTTCTCCTT TATGGAGGAC GACCAGGCCT ACCCATTCCT GCACACAAAG
GAGGACACTT ATGAGAACCT GCATAAGGTG CTGCAAGGCC GCCTGCCCGC CGTGGCCCAG
GCCGTGGCCC AGCTCGCAGG GCAGCTCCTC ATCCGGCTCA GCCACGATCG CCTGCTGCCC
CTCGACTTCG GCCGCTACGG GGACGTCGTC CTCAGGCACA TCGGGAACCT CAACGAGTTC
TCTGGGGACC TCAAGGCCCG CGGGCTGACC CTGCAGTGGG TGTACTCGGC GCGGGGGGAC
TACATCCGGG CGGCGGAAAA GCTGCGGCAG GAGATCTACA GCTCGGAGGA GAGAGACGAG
CGACTGACAC GCATGTACAA CGTGCGCATA ATGCGGGTGG AGTTCTACTT CCTTTCCCAG
TACGTGTCGC CAGCCGACTC CCCGTTCCGC CACATCTTCA TGGGCCGTGG AGACCACACG
CTGGGCGCCC TGCTGGACCA CCTGCGGCTG CTGCGCTCCA ACAGCTCCGG GACCCCCGGG
GCCACCTCCT CCACTGGCTT CCAGGAGAGC CGTTTCCGGC GTCAGCTAGC CCTGCTCACC
TGGACGCTGC AAGGGGCAGC CAATGCGCTT AGCGGGGATG TCTGGAACAT TGATAACAAC
TTCTGA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OHu16938
Clone ID Related Accession (Same CDS sequence) NM_001206855.1
Accession Version NM_001206855.1 Latest version! Documents for ORF clone product in dufault vector
Sequence Information ORF Nucleotide Sequence (Length: 1893bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ® Seamless cloning technology
Insert Structure linear
Update Date 2017-05-06
Organism Homo sapiens(Human)
Product transferrin receptor protein 2 isoform 2
Comment REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from BX384750.2 and AF067864.1. Transcript Variant: This variant (2) differs at the 5' end compared to variant 1, and initiates translation from an in-frame downstream AUG, resulting in an isoform (2, also known as beta) with a shorter N-terminus (lacking the transmembrane domain) compared to isoform 1. While there is transcript support for this variant (PMID:10409623), the protein is predicted. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## RNAseq introns :: single sample supports all introns SAMEA2155590, SAMEA2162895 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
1501
1561
1621
1681
1741
1801
1861
ATGGCCGCTC TGACTCAGGA CATTCGCGCG GCGCTCTCCC GCCAGAAGCT GGACCACGTG 
TGGACCGACA CGCACTACGT GGGGCTGCAA TTCCCGGATC CGGCTCACCC CAACACCCTG
CACTGGGTCG ATGAGGCCGG GAAGGTCGGA GAGCAGCTGC CGCTGGAGGA CCCTGACGTC
TACTGCCCCT ACAGCGCCAT CGGCAACGTC ACGGGAGAGC TGGTGTACGC CCACTACGGG
CGGCCCGAAG ACCTGCAGGA CCTGCGGGCC AGGGGCGTGG ATCCAGTGGG CCGCCTGCTG
CTGGTGCGCG TGGGGGTGAT CAGCTTCGCC CAGAAGGTGA CCAATGCTCA GGACTTCGGG
GCTCAAGGAG TGCTCATATA CCCAGAGCCA GCGGACTTCT CCCAGGACCC ACCCAAGCCA
AGCCTGTCCA GCCAGCAGGC AGTGTATGGA CATGTGCACC TGGGAACTGG AGACCCCTAC
ACACCTGGCT TCCCTTCCTT CAATCAAACC CAGTTCCCTC CAGTTGCATC ATCAGGCCTT
CCCAGCATCC CAGCCCAGCC CATCAGTGCA GACATTGCCT CCCGCCTGCT GAGGAAGCTC
AAAGGCCCTG TGGCCCCCCA AGAATGGCAG GGGAGCCTCC TAGGCTCCCC TTATCACCTG
GGCCCCGGGC CACGACTGCG GCTAGTGGTC AACAATCACA GGACCTCCAC CCCCATCAAC
AACATCTTCG GCTGCATCGA AGGCCGCTCA GAGCCAGATC ACTACGTTGT CATCGGGGCC
CAGAGGGATG CATGGGGCCC AGGAGCAGCT AAATCCGCTG TGGGGACGGC TATACTCCTG
GAGCTGGTGC GGACCTTTTC CTCCATGGTG AGCAACGGCT TCCGGCCCCG CAGAAGTCTC
CTCTTCATCA GCTGGGACGG TGGTGACTTT GGAAGCGTGG GCTCCACGGA GTGGCTAGAA
GGCTACCTCA GCGTGCTGCA CCTCAAAGCC GTAGTGTACG TGAGCCTGGA CAACGCAGTG
CTGGGGGATG ACAAGTTTCA TGCCAAGACC AGCCCCCTTC TGACAAGTCT CATTGAGAGT
GTCCTGAAGC AGGTGGATTC TCCCAACCAC AGTGGGCAGA CTCTCTATGA ACAGGTGGTG
TTCACCAATC CCAGCTGGGA TGCTGAGGTG ATCCGGCCCC TACCCATGGA CAGCAGTGCC
TATTCCTTCA CGGCCTTTGT GGGAGTCCCT GCCGTCGAGT TCTCCTTTAT GGAGGACGAC
CAGGCCTACC CATTCCTGCA CACAAAGGAG GACACTTATG AGAACCTGCA TAAGGTGCTG
CAAGGCCGCC TGCCCGCCGT GGCCCAGGCC GTGGCCCAGC TCGCAGGGCA GCTCCTCATC
CGGCTCAGCC ACGATCGCCT GCTGCCCCTC GACTTCGGCC GCTACGGGGA CGTCGTCCTC
AGGCACATCG GGAACCTCAA CGAGTTCTCT GGGGACCTCA AGGCCCGCGG GCTGACCCTG
CAGTGGGTGT ACTCGGCGCG GGGGGACTAC ATCCGGGCGG CGGAAAAGCT GCGGCAGGAG
ATCTACAGCT CGGAGGAGAG AGACGAGCGA CTGACACGCA TGTACAACGT GCGCATAATG
CGGGTGGAGT TCTACTTCCT TTCCCAGTAC GTGTCGCCAG CCGACTCCCC GTTCCGCCAC
ATCTTCATGG GCCGTGGAGA CCACACGCTG GGCGCCCTGC TGGACCACCT GCGGCTGCTG
CGCTCCAACA GCTCCGGGAC CCCCGGGGCC ACCTCCTCCA CTGGCTTCCA GGAGAGCCGT
TTCCGGCGTC AGCTAGCCCT GCTCACCTGG ACGCTGCAAG GGGCAGCCAA TGCGCTTAGC
GGGGATGTCT GGAACATTGA TAACAACTTC TGA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq NP_001193784.1
CDS135..2027
Misc Feature(1)252..824
Misc Feature(2)order(528..530,570..581,585..587,597..608,615..617,621..629)
Misc Feature(3)order(600..602,618..620)
Misc Feature(4)order(615..617,624..626)
Misc Feature(5)order(627..629,633..635,645..650)
Misc Feature(6)846..1547
Misc Feature(7)order(867..869,873..875,882..884,888..893,897..899,1029..1031,1035..1037,1086..1088,1095..1121)
Misc Feature(8)1641..1994
Exon (1)1..235
Exon (2)236..347
Exon (3)348..470
Exon (4)471..587
Exon (5)588..727
Exon (6)728..891
Exon (7)892..1011
Exon (8)1012..1094
Exon (9)1095..1158
Exon (10)1159..1226
Exon (11)1227..1303
Exon (12)1304..1388
Exon (13)1389..1616
Exon (14)1617..1757
Exon (15)1758..2468
Translation

Target ORF information:

RefSeq Version NM_001206855.1
Organism Homo sapiens(Human)
Definition Homo sapiens transferrin receptor 2 (TFR2), transcript variant 2, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
NM_001206855.1

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
1501
1561
1621
1681
1741
1801
1861
ATGGCCGCTC TGACTCAGGA CATTCGCGCG GCGCTCTCCC GCCAGAAGCT GGACCACGTG 
TGGACCGACA CGCACTACGT GGGGCTGCAA TTCCCGGATC CGGCTCACCC CAACACCCTG
CACTGGGTCG ATGAGGCCGG GAAGGTCGGA GAGCAGCTGC CGCTGGAGGA CCCTGACGTC
TACTGCCCCT ACAGCGCCAT CGGCAACGTC ACGGGAGAGC TGGTGTACGC CCACTACGGG
CGGCCCGAAG ACCTGCAGGA CCTGCGGGCC AGGGGCGTGG ATCCAGTGGG CCGCCTGCTG
CTGGTGCGCG TGGGGGTGAT CAGCTTCGCC CAGAAGGTGA CCAATGCTCA GGACTTCGGG
GCTCAAGGAG TGCTCATATA CCCAGAGCCA GCGGACTTCT CCCAGGACCC ACCCAAGCCA
AGCCTGTCCA GCCAGCAGGC AGTGTATGGA CATGTGCACC TGGGAACTGG AGACCCCTAC
ACACCTGGCT TCCCTTCCTT CAATCAAACC CAGTTCCCTC CAGTTGCATC ATCAGGCCTT
CCCAGCATCC CAGCCCAGCC CATCAGTGCA GACATTGCCT CCCGCCTGCT GAGGAAGCTC
AAAGGCCCTG TGGCCCCCCA AGAATGGCAG GGGAGCCTCC TAGGCTCCCC TTATCACCTG
GGCCCCGGGC CACGACTGCG GCTAGTGGTC AACAATCACA GGACCTCCAC CCCCATCAAC
AACATCTTCG GCTGCATCGA AGGCCGCTCA GAGCCAGATC ACTACGTTGT CATCGGGGCC
CAGAGGGATG CATGGGGCCC AGGAGCAGCT AAATCCGCTG TGGGGACGGC TATACTCCTG
GAGCTGGTGC GGACCTTTTC CTCCATGGTG AGCAACGGCT TCCGGCCCCG CAGAAGTCTC
CTCTTCATCA GCTGGGACGG TGGTGACTTT GGAAGCGTGG GCTCCACGGA GTGGCTAGAA
GGCTACCTCA GCGTGCTGCA CCTCAAAGCC GTAGTGTACG TGAGCCTGGA CAACGCAGTG
CTGGGGGATG ACAAGTTTCA TGCCAAGACC AGCCCCCTTC TGACAAGTCT CATTGAGAGT
GTCCTGAAGC AGGTGGATTC TCCCAACCAC AGTGGGCAGA CTCTCTATGA ACAGGTGGTG
TTCACCAATC CCAGCTGGGA TGCTGAGGTG ATCCGGCCCC TACCCATGGA CAGCAGTGCC
TATTCCTTCA CGGCCTTTGT GGGAGTCCCT GCCGTCGAGT TCTCCTTTAT GGAGGACGAC
CAGGCCTACC CATTCCTGCA CACAAAGGAG GACACTTATG AGAACCTGCA TAAGGTGCTG
CAAGGCCGCC TGCCCGCCGT GGCCCAGGCC GTGGCCCAGC TCGCAGGGCA GCTCCTCATC
CGGCTCAGCC ACGATCGCCT GCTGCCCCTC GACTTCGGCC GCTACGGGGA CGTCGTCCTC
AGGCACATCG GGAACCTCAA CGAGTTCTCT GGGGACCTCA AGGCCCGCGG GCTGACCCTG
CAGTGGGTGT ACTCGGCGCG GGGGGACTAC ATCCGGGCGG CGGAAAAGCT GCGGCAGGAG
ATCTACAGCT CGGAGGAGAG AGACGAGCGA CTGACACGCA TGTACAACGT GCGCATAATG
CGGGTGGAGT TCTACTTCCT TTCCCAGTAC GTGTCGCCAG CCGACTCCCC GTTCCGCCAC
ATCTTCATGG GCCGTGGAGA CCACACGCTG GGCGCCCTGC TGGACCACCT GCGGCTGCTG
CGCTCCAACA GCTCCGGGAC CCCCGGGGCC ACCTCCTCCA CTGGCTTCCA GGAGAGCCGT
TTCCGGCGTC AGCTAGCCCT GCTCACCTGG ACGCTGCAAG GGGCAGCCAA TGCGCTTAGC
GGGGATGTCT GGAACATTGA TAACAACTTC TGA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

book

Novel pathway for iron deficiency in pediatric non-alcoholic steatohepatitis.
Clinical nutrition (Edinburgh, Scotland)34(3)549-56(2015 Jun)
Moya D,Baker SS,Liu W,Garrick M,Kozielski R,Baker RD,Zhu L


book

Erythropoiesis and transferrin receptors.
Current opinion in hematology22(3)193-8(2015 May)
Moura IC,Hermine O,Lacombe C,Mayeux P


book

Regulation of cell surface transferrin receptor-2 by iron-dependent cleavage and release of a soluble form.
Haematologica100(4)458-65(2015 Apr)
Pagani A,Vieillevoye M,Nai A,Rausa M,Ladli M,Lacombe C,Mayeux P,Verdier F,Camaschella C,Silvestri L


book

CD81 promotes both the degradation of transferrin receptor 2 (TfR2) and the Tfr2-mediated maintenance of hepcidin expression.
The Journal of biological chemistry290(12)7841-50(2015 Mar)
Chen J,Enns CA


book

Novel loci affecting iron homeostasis and their effects in individuals at risk for hemochromatosis.
Nature communications54926(2014 Oct)
Benyamin B,Esko T,Ried JS,Radhakrishnan A,Vermeulen SH,Traglia M,Gögele M,Anderson D,Broer L,Podmore C,Luan J,Kutalik Z,Sanna S,van der Meer P,Tanaka T,Wang F,Westra HJ,Franke L,Mihailov E,Milani L,Hälldin J,Häldin J,Winkelmann J,Meitinger T,Thiery J,Peters A,Waldenberger M,Rendon A,Jolley J,Sambrook J,Kiemeney LA,Sweep FC,Sala CF,Schwienbacher C,Pichler I,Hui J,Demirkan A,Isaacs A,Amin N,Steri M,Waeber G,Verweij N,Powell JE,Nyholt DR,Heath AC,Madden PA,Visscher PM,Wright MJ,Montgomery GW,Martin NG,Hernandez D,Bandinelli S,van der Harst P,Uda M,Vollenweider P,Scott RA,Langenberg C,Wareham NJ,,van Duijn C,Beilby J,Pramstaller PP,Hicks AA,Ouwehand WH,Oexle K,Gieger C,Metspalu A,Camaschella C,Toniolo D,Swinkels DW,Whitfield JB


 
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