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TNNC2 cDNA ORF clone, Homo sapiens (human)

Gene Symbol TNNC2
Entrez Gene ID 7125
Full Name troponin C type 2 (fast)
General protein information
Preferred Names
troponin C, skeletal muscle
Names
troponin C, skeletal muscle
troponin C2, fast
Gene Type protein-coding
Organism Homo sapiens (human)
Genome

20

20q12-q13.11

Summary Troponin (Tn), a key protein complex in the regulation of striated muscle contraction, is composed of 3 subunits. The Tn-I subunit inhibits actomyosin ATPase, the Tn-T subunit binds tropomyosin and Tn-C, while the Tn-C subunit binds calcium and overcomes the inhibitory action of the troponin complex on actin filaments. The protein encoded by this gene is the Tn-C subunit. [provided by RefSeq, Jul 2008]. lac of sum
Disorder MIM:

191039


mRNA and Protein(s)

mRNA Protein Name
XM_011529031 XP_011527333 troponin C, skeletal muscle isoform X1
NM_003279 NP_003270 troponin C, skeletal muscle



Homo sapiens (human) TNNC2 NP_003270.1
Pan troglodytes (chimpanzee) TNNC2 XP_001157246.1
Macaca mulatta (Rhesus monkey) TNNC2 XP_001108623.1
Canis lupus familiaris (dog) TNNC2 XP_543023.2
Bos taurus (cattle) TNNC2 NP_001069841.1
Mus musculus (house mouse) Tnnc2 NP_033420.1
Rattus norvegicus (Norway rat) Tnnc2 NP_001032428.1
Gallus gallus (chicken) TNNC2 NP_990781.1
Danio rerio (zebrafish) tnnc2 NP_571638.1
Xenopus (Silurana) tropicalis (western clawed frog) tnnc2 NP_988957.1


GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following TNNC2 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the TNNC2 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

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***CloneID RefSeq Accession Definition **Vector *Turnaround time Price (USD) Select
OHu61061 XM_011529031 PREDICTED: Homo sapiens troponin C type 2 (fast) (TNNC2), transcript variant X1, mRNA. pcDNA3.1+/C-(K)DYK or customized vector 7-9 $69.30
$99.00
OHu04113
NM_003279 Homo sapiens troponin C type 2 (fast) (TNNC2), mRNA. pcDNA3.1+/C-(K)DYK or customized vector
in pcDNA3.1+/C-(K)DYK
$49.50-$69.30
$99.00

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.


CloneID OHu61061
Clone ID Related Accession (Same CDS sequence) XM_011529031
Accession Version XM_011529031.1 Documents for ORF clone product in dufault vector
Sequence Information ORF Nucleotide Sequence (Length: 438bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ® Seamless cloning technology
Insert Structure linear
Update Date 12-MAR-2015
Organism Homo sapiens (human)
Product troponin C, skeletal muscle isoform X1
Comment MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NT_011362.11) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Homo sapiens Annotation Release 107 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 6.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

1
61
121
181
241
301
361
421
ATGATCGCTG AGTTCAAGGC TGCCTTTGAC ATGTTTGATG CTGATGGTGG TGGGGACATC 
AGCGTCAAGG AGTTGGGCAC GGTGATGAGG ATGCTGGGCC AGACACCCAC CAAGGAGGAG
CTGGACGCCA TCATCGAGGA GGTGGATGAG GACGGCAGCG GCACCATCGA CTTCGAGGAG
TTCTTGGTCA TGATGGTGCG CCAGATGAAA GAGGACGCGA AAGGGAAGAG CGAGGAGGAG
CTGGCCGAGT GCTTCCGCAT CTTCGACAGG AATGCAGACG GCTACATCGA CCCGGAGGAG
CTGGCTGAGA TTTTCAGGGC CTCCGGGGAG CACGTGACGG ACGAGGAGAT CGAATCTCTG
ATGAAAGACG GCGACAAGAA CAACGACGGC CGCATTGACT TCGACGAGTT CCTGAAGATG
ATGGAGGGCG TGCAGTAA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq XP_011527333.1
CDS116..553
Misc Feature(1)119..538(+)
Misc Feature(2)125..310(+)
Misc Feature(3)152..295(+)
Misc Feature(4)353..538(+)
Misc Feature(5)380..523(+)
Translation

Target ORF information:

RefSeq Version XM_011529031
Organism Homo sapiens (human)
Definition PREDICTED: Homo sapiens troponin C type 2 (fast) (TNNC2), transcript variant X1, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
XM_011529031

ORF Insert Sequence:

1
61
121
181
241
301
361
421
ATGATCGCTG AGTTCAAGGC TGCCTTTGAC ATGTTTGATG CTGATGGTGG TGGGGACATC 
AGCGTCAAGG AGTTGGGCAC GGTGATGAGG ATGCTGGGCC AGACACCCAC CAAGGAGGAG
CTGGACGCCA TCATCGAGGA GGTGGATGAG GACGGCAGCG GCACCATCGA CTTCGAGGAG
TTCTTGGTCA TGATGGTGCG CCAGATGAAA GAGGACGCGA AAGGGAAGAG CGAGGAGGAG
CTGGCCGAGT GCTTCCGCAT CTTCGACAGG AATGCAGACG GCTACATCGA CCCGGAGGAG
CTGGCTGAGA TTTTCAGGGC CTCCGGGGAG CACGTGACGG ACGAGGAGAT CGAATCTCTG
ATGAAAGACG GCGACAAGAA CAACGACGGC CGCATTGACT TCGACGAGTT CCTGAAGATG
ATGGAGGGCG TGCAGTAA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OHu04113
Clone ID Related Accession (Same CDS sequence) NM_003279
Accession Version NM_003279.2 Documents for ORF clone product in dufault vector
Sequence Information ORF Nucleotide Sequence (Length: 483bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags COA
ORF Insert Method CloneEZ® Seamless cloning technology
Insert Structure linear
Update Date 15-MAR-2015
Organism Homo sapiens (human)
Product troponin C, skeletal muscle
Comment REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from BU854061.1, AI080746.1 and BC005323.1. On Jan 13, 2004 this sequence version replaced gi:4507616. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BF576408.1, BC005323.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2162946, SAMEA962337 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

1
61
121
181
241
301
361
421
481
ATGACGGACC AGCAGGCTGA GGCCAGGTCC TACCTCAGCG AAGAGATGAT CGCTGAGTTC 
AAGGCTGCCT TTGACATGTT TGATGCTGAT GGTGGTGGGG ACATCAGCGT CAAGGAGTTG
GGCACGGTGA TGAGGATGCT GGGCCAGACA CCCACCAAGG AGGAGCTGGA CGCCATCATC
GAGGAGGTGG ATGAGGACGG CAGCGGCACC ATCGACTTCG AGGAGTTCTT GGTCATGATG
GTGCGCCAGA TGAAAGAGGA CGCGAAAGGG AAGAGCGAGG AGGAGCTGGC CGAGTGCTTC
CGCATCTTCG ACAGGAATGC AGACGGCTAC ATCGACCCGG AGGAGCTGGC TGAGATTTTC
AGGGCCTCCG GGGAGCACGT GACGGACGAG GAGATCGAAT CTCTGATGAA AGACGGCGAC
AAGAACAACG ACGGCCGCAT TGACTTCGAC GAGTTCCTGA AGATGATGGA GGGCGTGCAG
TAA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq NP_003270.1
CDS67..549
Misc Feature(1)70..72(+)
Misc Feature(2)100..534(+)
Misc Feature(3)121..306(+)
Misc Feature(4)148..291(+)
Misc Feature(5)349..534(+)
Misc Feature(6)376..519(+)
Exon (1)1..69
Gene:TNNC2
Gene Synonym:
Exon (2)70..121
Gene:TNNC2
Gene Synonym:
Exon (3)122..265
Gene:TNNC2
Gene Synonym:
Exon (4)266..380
Gene:TNNC2
Gene Synonym:
Exon (5)381..517
Gene:TNNC2
Gene Synonym:
Exon (6)518..683
Gene:TNNC2
Gene Synonym:
Translation

Target ORF information:

RefSeq Version NM_003279
Organism Homo sapiens (human)
Definition Homo sapiens troponin C type 2 (fast) (TNNC2), mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
NM_003279

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
ATGACGGACC AGCAGGCTGA GGCCAGGTCC TACCTCAGCG AAGAGATGAT CGCTGAGTTC 
AAGGCTGCCT TTGACATGTT TGATGCTGAT GGTGGTGGGG ACATCAGCGT CAAGGAGTTG
GGCACGGTGA TGAGGATGCT GGGCCAGACA CCCACCAAGG AGGAGCTGGA CGCCATCATC
GAGGAGGTGG ATGAGGACGG CAGCGGCACC ATCGACTTCG AGGAGTTCTT GGTCATGATG
GTGCGCCAGA TGAAAGAGGA CGCGAAAGGG AAGAGCGAGG AGGAGCTGGC CGAGTGCTTC
CGCATCTTCG ACAGGAATGC AGACGGCTAC ATCGACCCGG AGGAGCTGGC TGAGATTTTC
AGGGCCTCCG GGGAGCACGT GACGGACGAG GAGATCGAAT CTCTGATGAA AGACGGCGAC
AAGAACAACG ACGGCCGCAT TGACTTCGAC GAGTTCCTGA AGATGATGGA GGGCGTGCAG
TAA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

 
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