Gene Symbol | SLC30A1 |
Entrez Gene ID | 7779 |
Full Name | solute carrier family 30 member 1 |
Synonyms | ZNT1,ZRC1 |
General protein information |
|
Gene Type | protein-coding |
Organism | Homo sapiens(human) |
Genome | |
Disorder MIM: |
ORF » Species Summary » Homo sapiens » SLC30A1 cDNA ORF clone
Gene Symbol | SLC30A1 |
Entrez Gene ID | 7779 |
Full Name | solute carrier family 30 member 1 |
Synonyms | ZNT1,ZRC1 |
General protein information |
|
Gene Type | protein-coding |
Organism | Homo sapiens(human) |
Genome | |
Disorder MIM: |
mRNA | Protein | Name |
---|---|---|
NM_021194.2 | NP_067017.2 | zinc transporter 1 |
NM_021194.3 | NP_067017.2 | zinc transporter 1 |
Kluyveromyces lactis | KLLA0F08723g | XP_455476.1 |
Magnaporthe oryzae (rice blast fungus) | MGG_03634 | XP_003716256.1 |
Rattus norvegicus (Norway rat) | Slc30a1 | NP_074044.1 |
Drosophila melanogaster (fruit fly) | ZnT63C | NP_728857.1 |
Saccharomyces cerevisiae (baker's yeast) | ZRC1 | NP_013970.1 |
Homo sapiens (human) | SLC30A1 | NP_067017.2 |
LOC711624 | XP_001108878.1 | |
Mus musculus (house mouse) | Slc30a1 | NP_033605.1 |
Anopheles gambiae (African malaria mosquito) | AgaP_AGAP005918 | XP_315949.4 |
Eremothecium gossypii | AGOS_ABR129C | NP_983076.2 |
Schizosaccharomyces pombe (fission yeast) | zhf1 | NP_593645.1 |
Neurospora crassa | NCU03145 | XP_964194.1 |
Pan troglodytes (chimpanzee) | SLC30A1 | XP_001170094.1 |
Canis lupus familiaris (dog) | SLC30A1 | XP_003434978.2 |
Bos taurus (cattle) | SLC30A1 | NP_001192822.1 |
Gallus gallus (chicken) | SLC30A1 | XP_419437.4 |
Danio rerio (zebrafish) | slc30a1a | NP_957173.1 |
Xenopus tropicalis (tropical clawed frog) | slc30a1 | NP_001007940.1 |
Zinc transporters protein level in postmortem brain of depressed subjects and suicide victims.
Rafalo-Ulinska A, Piotrowska J, Kryczyk A, Opoka W, Sowa-Kucma M, Misztak P, Rajkowska G, Stockmeier CA, Datka W, Nowak G, Szewczyk B
Journal of psychiatric research83220-229(2016 12)
Zinc sensing by metal-responsive transcription factor 1 (MTF1) controls metallothionein and ZnT1 expression to buffer the sensitivity of the transcriptome response to zinc.
Hardyman JE, Tyson J, Jackson KA, Aldridge C, Cockell SJ, Wakeling LA, Valentine RA, Ford D
Metallomics : integrated biometal science8(3)337-43(2016 Mar)
Heterodimerization, altered subcellular localization, and function of multiple zinc transporters in viable cells using bimolecular fluorescence complementation.
Golan Y, Berman B, Assaraf YG
The Journal of biological chemistry290(14)9050-63(2015 Apr)
ZnT-1 extrudes zinc from mammalian cells functioning as a Zn(2+)/H(+) exchanger.
Shusterman E, Beharier O, Shiri L, Zarivach R, Etzion Y, Campbell CR, Lee IH, Okabayashi K, Dinudom A, Cook DI, Katz A, Moran A
Metallomics : integrated biometal science6(9)1656-63(2014 Sep)
The alteration of zinc transporter gene expression is associated with inflammatory markers in obese women.
Noh H, Paik HY, Kim J, Chung J
Biological trace element research158(1)1-8(2014 Apr)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
This study showed that there was a significant increase in protein levels of ZnT1 in the prefrontal cortex in Major depressive disorder, relative to control subjects
Title: Zinc transporters protein level in postmortem brain of depressed subjects and suicide victims.
MTF1 heads a hierarchy of zinc sensors, and through controlling the expression of a raft of metallothioneins and other key proteins involved in controlling intracellular zinc levels (e.g. ZnT1) alters zinc buffering capacity and total cellular zinc content.
Title: Zinc sensing by metal-responsive transcription factor 1 (MTF1) controls metallothionein and ZnT1 expression to buffer the sensitivity of the transcriptome response to zinc.
ZnT-1 extrudes zinc from mammalian cells by functioning as a Zn(2+)/H(+) exchanger.
Title: ZnT-1 extrudes zinc from mammalian cells functioning as a Zn(2+)/H(+) exchanger.
Data indicate that zinc transporters ZnT1 and Zip1 were the most abundantly expressed zinc transporters in leukocytes.
Title: The alteration of zinc transporter gene expression is associated with inflammatory markers in obese women.
Data indicate that the expression levels of ZnT and ZIP families in the three cell lines, when treated with high concentration of ZnSO4, increased and decreased corresponding to their functions, respectively.
Title: Effects of exogenous zinc on cell cycle, apoptosis and viability of MDAMB231, HepG2 and 293 T cells.
The following SLC30A1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the SLC30A1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
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CloneID | OHu13086 | |
Clone ID Related Accession (Same CDS sequence) | NM_021194.2 , NM_021194.3 | |
Accession Version | NM_021194.2 | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1524bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2017-09-30 | |
Organism | Homo sapiens(human) | |
Product | zinc transporter 1 | |
Comment | Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AW183618.1, AI621266.1, AI467909.1, BE744293.1, AA853540.1, CB990012.1, BF057194.1 and CF529684.1. On Sep 20, 2004 this sequence version replaced NM_021194.1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1163655.116895.1, SRR1803614.261477.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2145774, SAMEA2158188 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end. |
1 | ATGGGGTGTT GGGGTCGGAA CCGGGGCCGG CTGCTGTGCA TGCTGGCGCT GACCTTCATG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_067017.2 |
CDS | 146..1669 |
Translation |
Target ORF information:
Target ORF information:
|
NM_021194.2 |
1 | ATGGGGTGTT GGGGTCGGAA CCGGGGCCGG CTGCTGTGCA TGCTGGCGCT GACCTTCATG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OHu13086 | |
Clone ID Related Accession (Same CDS sequence) | NM_021194.2 , NM_021194.3 | |
Accession Version | NM_021194.3 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1524bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-11-16 | |
Organism | Homo sapiens(human) | |
Product | zinc transporter 1 | |
Comment | Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AC105275.3, AW183618.1, AI621266.1, AI467909.1, BE744293.1, AA853540.1, CB990012.1, BF057194.1 and CF529684.1. On Nov 22, 2018 this sequence version replaced NM_021194.2. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1803612.57966.1, SRR1803615.67741.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2145774, SAMEA2158188 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000367001.5/ ENSP00000355968.4 RefSeq Select criteria :: based on single protein-coding transcript ##RefSeq-Attributes-END## COMPLETENESS: full length. |
1 | ATGGGGTGTT GGGGTCGGAA CCGGGGCCGG CTGCTGTGCA TGCTGGCGCT GACCTTCATG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_067017.2 |
CDS | 550..2073 |
Translation |
Target ORF information:
Target ORF information:
|
NM_021194.3 |
1 | ATGGGGTGTT GGGGTCGGAA CCGGGGCCGG CTGCTGTGCA TGCTGGCGCT GACCTTCATG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
Zinc transporters protein level in postmortem brain of depressed subjects and suicide victims. |
Zinc sensing by metal-responsive transcription factor 1 (MTF1) controls metallothionein and ZnT1 expression to buffer the sensitivity of the transcriptome response to zinc. |
Heterodimerization, altered subcellular localization, and function of multiple zinc transporters in viable cells using bimolecular fluorescence complementation. |
ZnT-1 extrudes zinc from mammalian cells functioning as a Zn(2+)/H(+) exchanger. |
The alteration of zinc transporter gene expression is associated with inflammatory markers in obese women. |