ARHGAP10 cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Gene Symbol	ARHGAP10
Entrez Gene ID	79658
Full Name	Rho GTPase activating protein 10
Synonyms	GRAF2,PS-GAP,PSGAP
General protein information	Preferred Names Rho GTPase activating protein 10 Names rho GTPase-activating protein 10 GTPase regulator associated with focal adhesion kinase 2 graf-related protein 2 rho-type GTPase-activating protein 10
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 4 Map Location: 4q31.23
Disorder MIM:	609746

mRNA and Protein(s)

mRNA	Protein	Name
NM_024605.3	NP_078881.3	rho GTPase-activating protein 10
XM_005263215.3	XP_005263272.1	rho GTPase-activating protein 10 isoform X1
NM_024605.4	NP_078881.3	rho GTPase-activating protein 10
XM_017008602.1	XP_016864091.1	rho GTPase-activating protein 10 isoform X2

Pathways from BioSystems

Homologies

Homo sapiens (human)	ARHGAP10	NP_078881.3
Bos taurus (cattle)	ARHGAP10	NP_001070298.1
	ARHGAP10	XP_001096942.1
Mus musculus (house mouse)	Arhgap10	NP_084389.2
Rattus norvegicus (Norway rat)	Arhgap10	NP_001102971.1
Gallus gallus (chicken)	ARHGAP10	XP_420436.1
Danio rerio (zebrafish)	arhgap10	NP_001038715.1
Pan troglodytes (chimpanzee)	ARHGAP10	XP_003310530.1
Canis lupus familiaris (dog)	ARHGAP10	XP_539757.2
Xenopus tropicalis (tropical clawed frog)	arhgap10	XP_002933548.2

Gene Ontology
Bibliography

Related articles in PubMed

ARHGAP10, downregulated in ovarian cancer, suppresses tumorigenicity of ovarian cancer cells.
Luo N, Guo J, Chen L, Yang W, Qu X, Cheng Z
Cell death & disease7e2157(2016 Mar)

Genome-wide analysis of polymorphisms associated with cytokine responses in smallpox vaccine recipients.
Kennedy RB, Ovsyannikova IG, Pankratz VS, Haralambieva IH, Vierkant RA, Poland GA
Human genetics131(9)1403-21(2012 Sep)

A genome-wide association study of prognosis in breast cancer.
Azzato EM, Pharoah PD, Harrington P, Easton DF, Greenberg D, Caporaso NE, Chanock SJ, Hoover RN, Thomas G, Hunter DJ, Kraft P
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology19(4)1140-3(2010 Apr)

A genomewide association study of nicotine and alcohol dependence in Australian and Dutch populations.
Lind PA, Macgregor S, Vink JM, Pergadia ML, Hansell NK, de Moor MH, Smit AB, Hottenga JJ, Richter MM, Heath AC, Martin NG, Willemsen G, de Geus EJ, Vogelzangs N, Penninx BW, Whitfield JB, Montgomery GW, Boomsma DI, Madden PA
Twin research and human genetics : the official journal of the International Society for Twin Studies13(1)10-29(2010 Feb)

A genome-wide association scan of RR and QT interval duration in 3 European genetically isolated populations: the EUROSPAN project.
Marroni F, Pfeufer A, Aulchenko YS, Franklin CS, Isaacs A, Pichler I, Wild SH, Oostra BA, Wright AF, Campbell H, Witteman JC, K??b S, Hicks AA, Gyllensten U, Rudan I, Meitinger T, Pattaro C, van Duijn CM, Wilson JF, Pramstaller PP,
Circulation. Cardiovascular genetics2(4)322-8(2009 Aug)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

ARHGAP10 may serve as a tumor suppressor through inactivating Cdc42, as well as inhibiting cell cycle, replication and BER pathways.
Title: ARHGAP10, downregulated in ovarian cancer, suppresses tumorigenicity of ovarian cancer cells.

Clinical trial of gene-disease association and gene-environment interaction. (HuGE Navigator)
Title: Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score.

Observational study and genome-wide association study of gene-disease association. (HuGE Navigator)
Title: A genome-wide association study of prognosis in breast cancer.

In the Australian GWAS, one SNP achieved genomewide significance (p < 5 x 10(-8)) for ND (rs964170 in ARHGAP10 on chromosome 4, p = 4.43 x 10(-8)).
Title: A genomewide association study of nicotine and alcohol dependence in Australian and Dutch populations.

Observational study of gene-disease association. (HuGE Navigator)
Title: Mutation of ARHGAP9 in patients with coronary spastic angina.

The following ARHGAP10 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the ARHGAP10 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

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***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu04124	NM_024605.4 Latest version!	Homo sapiens Rho GTPase activating protein 10 (ARHGAP10), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5-7	$391.30 $559.00
OHu39070	XM_005263215.3 Latest version!	Homo sapiens Rho GTPase activating protein 10 (ARHGAP10), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	12-14	$391.30 $559.00
OHu95397	XM_017008602.1 Latest version!	Homo sapiens Rho GTPase activating protein 10 (ARHGAP10), transcript variant X2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	14-16	$391.30 $559.00
View Old Accession Versions >>
OHu04124	NM_024605.3	Homo sapiens Rho GTPase activating protein 10 (ARHGAP10), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5-7	$391.30 $559.00
Hide Old Accession Versions >>

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

ARHGAP10 ( NM_024605.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_078881.3 Homo sapiens Rho GTPase activating protein 10 (ARHGAP10), mRNA.

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CloneID	OHu04124
Clone ID Related Accession (Same CDS sequence)	NM_024605.3 , NM_024605.4
Accession Version	NM_024605.3	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2361bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2018-06-22
Organism	Homo sapiens(human)
Product	rho GTPase-activating protein 10
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AK123785.1 and BC011920.2. On or before Aug 30, 2004 this sequence version replaced XM_496719.1, NM_024605.2. ##Evidence-Data-START## Transcript exon combination :: BC128055.1, SRR1803613.144310.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END##

ATGGGGCTGC AGCCCCTGGA GTTCAGCGAC TGCTACCTCG ACAGCCCGTG GTTCCGGGAG 
AGGATCCGCG CTCACGAAGC GGAACTCGAG AGGACCAACA AGTTCATCAA AGAGCTCATT 
AAGGACGGGA AGAACCTCAT CGCTGCGACG AAAAGTCTGT CAGTGGCCCA GCGGAAGTTT 
GCTCATTCAC TCAGAGACTT TAAGTTTGAG TTTATCGGTG ATGCTGTGAC AGATGATGAA 
CGATGCATAG ATGCTTCCTT ACGTGAATTT TCAAATTTTT TGAAGAATCT GGAGGAACAG 
AGAGAAATTA TGGCATTAAG TGTAACTGAA ACCCTGATTA AACCCTTGGA AAAATTCAGA 
AAAGAGCAAC TTGGAGCTGT AAAGGAAGAA AAAAAGAAGT TTGACAAAGA GACAGAAAAG 
AATTATAGTC TAATTGATAA ACATTTGAAT TTATCAGCAA AAAAGAAAGA CTCACATTTA 
CAAGAGGCAG ATATCCAAGT AGAGCAGAAC CGGCAACACT TCTATGAACT GTCTCTCGAG 
TATGTGTGTA AGCTGCAGGA AATCCAAGAA AGAAAGAAGT TTGAGTTTGT GGAACCTATG 
CTGTCATTTT TTCAGGGGAT GTTTACCTTC TATCATCAGG GCCATGAACT TGCCAAAGAC 
TTCAATCACT ACAAAATGGA ACTACAGATC AACATTCAGA ATACACGGAA TCGATTTGAA 
GGAACAAGGT CAGAAGTGGA AGAGCTCATG AACAAAATCA GACAGAATCC CAAGGACCAC 
AAACGAGCAA GTCAGTTTAC AGCCGAAGGC TACCTGTATG TCCAGGAAAA AAGGCCTGCT 
CCGTTTGGTT CCAGTTGGGT CAAACACTAT TGCATGTATC GAAAAGCAGC AAAGAAGTTC 
AACATGATCC CATTTGAGCA CAGATCTGGA GGGAAACTTG GGGACGGAGA GGTGTTCTTT 
TTGAAAGAAT GTACCAAGAG GCATACTGAC TCCATTGACA GAAGGTTTTG TTTTGACATA 
GAAGCTGCTG ATCGGCCTGG CGTTTCCTTG ACCATGCAGG CATTTTCCGA AGAGGAAAGG 
AAGCAGTGGT TGGAAGCTCT GGGTGGAAAG GAAGCTCTGT CCCATAGTTT TAATACAGCC 
ATCATCCCAA GACCAGAAGG AAATGCACAG TTGGATAAGA TGGGGTTCAC AATTATCAGA 
AAATGCATCA GTGCCGTTGA AACACGAGGT ATAAATGACC AAGGATTGTA CAGAGTTGTG 
GGGGTGAGTT CAAAGGTCCA GAGACTTCTG AGTATGTTGA TGGATGTAAA AACATGCAAT 
GAGGTGGACC TGGAGAATTC TGCAGATTGG GAAGTGAAGA CAATAACAAG TGCCTTGAAA 
CAGTATTTGA GGAGTCTTCC AGAGCCTCTC ATGACCTATG AGTTACATGG AGATTTCATT 
GTTCCAGCCA AAAGCGGCAG CCCAGAATCT CGTGTTAATG CGATCCATTT CTTGGTACAC 
AAACTGCCAG AGAAGAATAA AGAGATGTTG GATATTTTGG TGAAACACTT AACAAATGTT 
TCAAATCACT CCAAGCAGAA CCTGATGACT GTGGCAAACT TAGGAGTGGT GTTTGGACCA 
ACTCTGATGA GGCCACAGGA AGAAACTGTC GCTGCCCTCA TGGACTTGAA GTTTCAGAAT 
ATTGTTGTGG AAATCTTAAT TGAAAACCAT GAAAAGATTT TTCGGACGCC GCCCGATACT 
ACATTCCCTG AGCCCACCTG CCTGTCAGCA TCACCCCCAA ATGCGCCACC AAGGCAGTCG 
AAGAGACAAG GCCAGAGAAC CAAGAGGCCC GTGGCCGTCT ACAATCTTTG TCTGGAGCTG 
GAAGATGGTG ACAATCCTTA CCCTTCCAAG GAGGACACCC CTACCAGCAG TCTGGACTCA 
CTTTCCTCCC CGTCTCCCGT GACTACAGCT GTCCCTGGGC CTCCTGGACC AGACAAAAAC 
CACCTTCTGG CAGATGGAGG GAGCTTTGGA GACTGGGCAT CCACTATCCC AGGCCAGACC 
CGATCGTCTA TGGTCCAGTG GCTTAACCCA CAGTCTCCAA CCACAACAAG CTCCAACTCA 
GCTGTGACAC CTCTTTCACC CGGGTCGTCC CCTTTCCCCT TTTCTCCTCC TGCTACTGTA 
GCGGACAAGC CACCTGAAAG CATCCGCAGT CGGAAGGCTC GAGCCGTGTA TCCGTGTGAA 
GCAGAACACA GCTCGGAATT ATCTTTTGAA ATAGGAGCAA TTTTTGAGGA TGTACAAACC 
TCCAGGGAAC CTGGCTGGCT AGAAGGGACT CTGAACGGCA AGAGGGGGCT GATTCCACAG 
AACTACGTCA AGCTGCTGTA G

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_078881.3
CDS	1..2361
Translation	MGLQPLEFSDCYLDSPWFRERIRAHEAELERTNKFIKELIKDGKNLIAATKSLSVAQRKFAHSLRDFKFEFIGDAVTDDERCIDASLREFSNFLKNLEEQREIMALSVTETLIKPLEKFRKEQLGAVKEEKKKFDKETEKNYSLIDKHLNLSAKKKDSHLQEADIQVEQNRQHFYELSLEYVCKLQEIQERKKFEFVEPMLSFFQGMFTFYHQGHELAKDFNHYKMELQINIQNTRNRFEGTRSEVEELMNKIRQNPKDHKRASQFTAEGYLYVQEKRPAPFGSSWVKHYCMYRKAAKKFNMIPFEHRSGGKLGDGEVFFLKECTKRHTDSIDRRFCFDIEAADRPGVSLTMQAFSEEERKQWLEALGGKEALSHSFNTAIIPRPEGNAQLDKMGFTIIRKCISAVETRGINDQGLYRVVGVSSKVQRLLSMLMDVKTCNEVDLENSADWEVKTITSALKQYLRSLPEPLMTYELHGDFIVPAKSGSPESRVNAIHFLVHKLPEKNKEMLDILVKHLTNVSNHSKQNLMTVANLGVVFGPTLMRPQEETVAALMDLKFQNIVVEILIENHEKIFRTPPDTTFPEPTCLSASPPNAPPRQSKRQGQRTKRPVAVYNLCLELEDGDNPYPSKEDTPTSSLDSLSSPSPVTTAVPGPPGPDKNHLLADGGSFGDWASTIPGQTRSSMVQWLNPQSPTTTSSNSAVTPLSPGSSPFPFSPPATVADKPPESIRSRKARAVYPCEAEHSSELSFEIGAIFEDVQTSREPGWLEGTLNGKRGLIPQNYVKLL

Target ORF information:

RefSeq Version	NM_024605.3
Organism	Homo sapiens(human)
Definition	Homo sapiens Rho GTPase activating protein 10 (ARHGAP10), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_024605.3

ORF Insert Sequence:

ATGGGGCTGC AGCCCCTGGA GTTCAGCGAC TGCTACCTCG ACAGCCCGTG GTTCCGGGAG 
AGGATCCGCG CTCACGAAGC GGAACTCGAG AGGACCAACA AGTTCATCAA AGAGCTCATT 
AAGGACGGGA AGAACCTCAT CGCTGCGACG AAAAGTCTGT CAGTGGCCCA GCGGAAGTTT 
GCTCATTCAC TCAGAGACTT TAAGTTTGAG TTTATCGGTG ATGCTGTGAC AGATGATGAA 
CGATGCATAG ATGCTTCCTT ACGTGAATTT TCAAATTTTT TGAAGAATCT GGAGGAACAG 
AGAGAAATTA TGGCATTAAG TGTAACTGAA ACCCTGATTA AACCCTTGGA AAAATTCAGA 
AAAGAGCAAC TTGGAGCTGT AAAGGAAGAA AAAAAGAAGT TTGACAAAGA GACAGAAAAG 
AATTATAGTC TAATTGATAA ACATTTGAAT TTATCAGCAA AAAAGAAAGA CTCACATTTA 
CAAGAGGCAG ATATCCAAGT AGAGCAGAAC CGGCAACACT TCTATGAACT GTCTCTCGAG 
TATGTGTGTA AGCTGCAGGA AATCCAAGAA AGAAAGAAGT TTGAGTTTGT GGAACCTATG 
CTGTCATTTT TTCAGGGGAT GTTTACCTTC TATCATCAGG GCCATGAACT TGCCAAAGAC 
TTCAATCACT ACAAAATGGA ACTACAGATC AACATTCAGA ATACACGGAA TCGATTTGAA 
GGAACAAGGT CAGAAGTGGA AGAGCTCATG AACAAAATCA GACAGAATCC CAAGGACCAC 
AAACGAGCAA GTCAGTTTAC AGCCGAAGGC TACCTGTATG TCCAGGAAAA AAGGCCTGCT 
CCGTTTGGTT CCAGTTGGGT CAAACACTAT TGCATGTATC GAAAAGCAGC AAAGAAGTTC 
AACATGATCC CATTTGAGCA CAGATCTGGA GGGAAACTTG GGGACGGAGA GGTGTTCTTT 
TTGAAAGAAT GTACCAAGAG GCATACTGAC TCCATTGACA GAAGGTTTTG TTTTGACATA 
GAAGCTGCTG ATCGGCCTGG CGTTTCCTTG ACCATGCAGG CATTTTCCGA AGAGGAAAGG 
AAGCAGTGGT TGGAAGCTCT GGGTGGAAAG GAAGCTCTGT CCCATAGTTT TAATACAGCC 
ATCATCCCAA GACCAGAAGG AAATGCACAG TTGGATAAGA TGGGGTTCAC AATTATCAGA 
AAATGCATCA GTGCCGTTGA AACACGAGGT ATAAATGACC AAGGATTGTA CAGAGTTGTG 
GGGGTGAGTT CAAAGGTCCA GAGACTTCTG AGTATGTTGA TGGATGTAAA AACATGCAAT 
GAGGTGGACC TGGAGAATTC TGCAGATTGG GAAGTGAAGA CAATAACAAG TGCCTTGAAA 
CAGTATTTGA GGAGTCTTCC AGAGCCTCTC ATGACCTATG AGTTACATGG AGATTTCATT 
GTTCCAGCCA AAAGCGGCAG CCCAGAATCT CGTGTTAATG CGATCCATTT CTTGGTACAC 
AAACTGCCAG AGAAGAATAA AGAGATGTTG GATATTTTGG TGAAACACTT AACAAATGTT 
TCAAATCACT CCAAGCAGAA CCTGATGACT GTGGCAAACT TAGGAGTGGT GTTTGGACCA 
ACTCTGATGA GGCCACAGGA AGAAACTGTC GCTGCCCTCA TGGACTTGAA GTTTCAGAAT 
ATTGTTGTGG AAATCTTAAT TGAAAACCAT GAAAAGATTT TTCGGACGCC GCCCGATACT 
ACATTCCCTG AGCCCACCTG CCTGTCAGCA TCACCCCCAA ATGCGCCACC AAGGCAGTCG 
AAGAGACAAG GCCAGAGAAC CAAGAGGCCC GTGGCCGTCT ACAATCTTTG TCTGGAGCTG 
GAAGATGGTG ACAATCCTTA CCCTTCCAAG GAGGACACCC CTACCAGCAG TCTGGACTCA 
CTTTCCTCCC CGTCTCCCGT GACTACAGCT GTCCCTGGGC CTCCTGGACC AGACAAAAAC 
CACCTTCTGG CAGATGGAGG GAGCTTTGGA GACTGGGCAT CCACTATCCC AGGCCAGACC 
CGATCGTCTA TGGTCCAGTG GCTTAACCCA CAGTCTCCAA CCACAACAAG CTCCAACTCA 
GCTGTGACAC CTCTTTCACC CGGGTCGTCC CCTTTCCCCT TTTCTCCTCC TGCTACTGTA 
GCGGACAAGC CACCTGAAAG CATCCGCAGT CGGAAGGCTC GAGCCGTGTA TCCGTGTGAA 
GCAGAACACA GCTCGGAATT ATCTTTTGAA ATAGGAGCAA TTTTTGAGGA TGTACAAACC 
TCCAGGGAAC CTGGCTGGCT AGAAGGGACT CTGAACGGCA AGAGGGGGCT GATTCCACAG 
AACTACGTCA AGCTGCTGTA G

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

ARHGAP10 ( NM_024605.4 ) cDNA ORF clone, Homo sapiens(human) -> NP_078881.3 Homo sapiens Rho GTPase activating protein 10 (ARHGAP10), mRNA.

Price & Availability↑

CloneID	OHu04124
Clone ID Related Accession (Same CDS sequence)	NM_024605.3 , NM_024605.4
Accession Version	NM_024605.4 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2361bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-10-25
Organism	Homo sapiens(human)
Product	rho GTPase-activating protein 10
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AC093835.3, AK123785.1 and BC011920.2. On May 17, 2019 this sequence version replaced NM_024605.3. ##Evidence-Data-START## Transcript exon combination :: SRR1803613.60265.1, SRR1803611.217951.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000336498.8/ ENSP00000336923.3 RefSeq Select criteria :: based on conservation, expression, longest protein ##RefSeq-Attributes-END##

ATGGGGCTGC AGCCCCTGGA GTTCAGCGAC TGCTACCTCG ACAGCCCGTG GTTCCGGGAG 
AGGATCCGCG CTCACGAAGC GGAACTCGAG AGGACCAACA AGTTCATCAA AGAGCTCATT 
AAGGACGGGA AGAACCTCAT CGCTGCGACG AAAAGTCTGT CAGTGGCCCA GCGGAAGTTT 
GCTCATTCAC TCAGAGACTT TAAGTTTGAG TTTATCGGTG ATGCTGTGAC AGATGATGAA 
CGATGCATAG ATGCTTCCTT ACGTGAATTT TCAAATTTTT TGAAGAATCT GGAGGAACAG 
AGAGAAATTA TGGCATTAAG TGTAACTGAA ACCCTGATTA AACCCTTGGA AAAATTCAGA 
AAAGAGCAAC TTGGAGCTGT AAAGGAAGAA AAAAAGAAGT TTGACAAAGA GACAGAAAAG 
AATTATAGTC TAATTGATAA ACATTTGAAT TTATCAGCAA AAAAGAAAGA CTCACATTTA 
CAAGAGGCAG ATATCCAAGT AGAGCAGAAC CGGCAACACT TCTATGAACT GTCTCTCGAG 
TATGTGTGTA AGCTGCAGGA AATCCAAGAA AGAAAGAAGT TTGAGTTTGT GGAACCTATG 
CTGTCATTTT TTCAGGGGAT GTTTACCTTC TATCATCAGG GCCATGAACT TGCCAAAGAC 
TTCAATCACT ACAAAATGGA ACTACAGATC AACATTCAGA ATACACGGAA TCGATTTGAA 
GGAACAAGGT CAGAAGTGGA AGAGCTCATG AACAAAATCA GACAGAATCC CAAGGACCAC 
AAACGAGCAA GTCAGTTTAC AGCCGAAGGC TACCTGTATG TCCAGGAAAA AAGGCCTGCT 
CCGTTTGGTT CCAGTTGGGT CAAACACTAT TGCATGTATC GAAAAGCAGC AAAGAAGTTC 
AACATGATCC CATTTGAGCA CAGATCTGGA GGGAAACTTG GGGACGGAGA GGTGTTCTTT 
TTGAAAGAAT GTACCAAGAG GCATACTGAC TCCATTGACA GAAGGTTTTG TTTTGACATA 
GAAGCTGCTG ATCGGCCTGG CGTTTCCTTG ACCATGCAGG CATTTTCCGA AGAGGAAAGG 
AAGCAGTGGT TGGAAGCTCT GGGTGGAAAG GAAGCTCTGT CCCATAGTTT TAATACAGCC 
ATCATCCCAA GACCAGAAGG AAATGCACAG TTGGATAAGA TGGGGTTCAC AATTATCAGA 
AAATGCATCA GTGCCGTTGA AACACGAGGT ATAAATGACC AAGGATTGTA CAGAGTTGTG 
GGGGTGAGTT CAAAGGTCCA GAGACTTCTG AGTATGTTGA TGGATGTAAA AACATGCAAT 
GAGGTGGACC TGGAGAATTC TGCAGATTGG GAAGTGAAGA CAATAACAAG TGCCTTGAAA 
CAGTATTTGA GGAGTCTTCC AGAGCCTCTC ATGACCTATG AGTTACATGG AGATTTCATT 
GTTCCAGCCA AAAGCGGCAG CCCAGAATCT CGTGTTAATG CGATCCATTT CTTGGTACAC 
AAACTGCCAG AGAAGAATAA AGAGATGTTG GATATTTTGG TGAAACACTT AACAAATGTT 
TCAAATCACT CCAAGCAGAA CCTGATGACT GTGGCAAACT TAGGAGTGGT GTTTGGACCA 
ACTCTGATGA GGCCACAGGA AGAAACTGTC GCTGCCCTCA TGGACTTGAA GTTTCAGAAT 
ATTGTTGTGG AAATCTTAAT TGAAAACCAT GAAAAGATTT TTCGGACGCC GCCCGATACT 
ACATTCCCTG AGCCCACCTG CCTGTCAGCA TCACCCCCAA ATGCGCCACC AAGGCAGTCG 
AAGAGACAAG GCCAGAGAAC CAAGAGGCCC GTGGCCGTCT ACAATCTTTG TCTGGAGCTG 
GAAGATGGTG ACAATCCTTA CCCTTCCAAG GAGGACACCC CTACCAGCAG TCTGGACTCA 
CTTTCCTCCC CGTCTCCCGT GACTACAGCT GTCCCTGGGC CTCCTGGACC AGACAAAAAC 
CACCTTCTGG CAGATGGAGG GAGCTTTGGA GACTGGGCAT CCACTATCCC AGGCCAGACC 
CGATCGTCTA TGGTCCAGTG GCTTAACCCA CAGTCTCCAA CCACAACAAG CTCCAACTCA 
GCTGTGACAC CTCTTTCACC CGGGTCGTCC CCTTTCCCCT TTTCTCCTCC TGCTACTGTA 
GCGGACAAGC CACCTGAAAG CATCCGCAGT CGGAAGGCTC GAGCCGTGTA TCCGTGTGAA 
GCAGAACACA GCTCGGAATT ATCTTTTGAA ATAGGAGCAA TTTTTGAGGA TGTACAAACC 
TCCAGGGAAC CTGGCTGGCT AGAAGGGACT CTGAACGGCA AGAGGGGGCT GATTCCACAG 
AACTACGTCA AGCTGCTGTA G

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_078881.3
CDS	215..2575
Translation	MGLQPLEFSDCYLDSPWFRERIRAHEAELERTNKFIKELIKDGKNLIAATKSLSVAQRKFAHSLRDFKFEFIGDAVTDDERCIDASLREFSNFLKNLEEQREIMALSVTETLIKPLEKFRKEQLGAVKEEKKKFDKETEKNYSLIDKHLNLSAKKKDSHLQEADIQVEQNRQHFYELSLEYVCKLQEIQERKKFEFVEPMLSFFQGMFTFYHQGHELAKDFNHYKMELQINIQNTRNRFEGTRSEVEELMNKIRQNPKDHKRASQFTAEGYLYVQEKRPAPFGSSWVKHYCMYRKAAKKFNMIPFEHRSGGKLGDGEVFFLKECTKRHTDSIDRRFCFDIEAADRPGVSLTMQAFSEEERKQWLEALGGKEALSHSFNTAIIPRPEGNAQLDKMGFTIIRKCISAVETRGINDQGLYRVVGVSSKVQRLLSMLMDVKTCNEVDLENSADWEVKTITSALKQYLRSLPEPLMTYELHGDFIVPAKSGSPESRVNAIHFLVHKLPEKNKEMLDILVKHLTNVSNHSKQNLMTVANLGVVFGPTLMRPQEETVAALMDLKFQNIVVEILIENHEKIFRTPPDTTFPEPTCLSASPPNAPPRQSKRQGQRTKRPVAVYNLCLELEDGDNPYPSKEDTPTSSLDSLSSPSPVTTAVPGPPGPDKNHLLADGGSFGDWASTIPGQTRSSMVQWLNPQSPTTTSSNSAVTPLSPGSSPFPFSPPATVADKPPESIRSRKARAVYPCEAEHSSELSFEIGAIFEDVQTSREPGWLEGTLNGKRGLIPQNYVKLL

Target ORF information:

RefSeq Version	NM_024605.4
Organism	Homo sapiens(human)
Definition	Homo sapiens Rho GTPase activating protein 10 (ARHGAP10), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_024605.4

ORF Insert Sequence:

ATGGGGCTGC AGCCCCTGGA GTTCAGCGAC TGCTACCTCG ACAGCCCGTG GTTCCGGGAG 
AGGATCCGCG CTCACGAAGC GGAACTCGAG AGGACCAACA AGTTCATCAA AGAGCTCATT 
AAGGACGGGA AGAACCTCAT CGCTGCGACG AAAAGTCTGT CAGTGGCCCA GCGGAAGTTT 
GCTCATTCAC TCAGAGACTT TAAGTTTGAG TTTATCGGTG ATGCTGTGAC AGATGATGAA 
CGATGCATAG ATGCTTCCTT ACGTGAATTT TCAAATTTTT TGAAGAATCT GGAGGAACAG 
AGAGAAATTA TGGCATTAAG TGTAACTGAA ACCCTGATTA AACCCTTGGA AAAATTCAGA 
AAAGAGCAAC TTGGAGCTGT AAAGGAAGAA AAAAAGAAGT TTGACAAAGA GACAGAAAAG 
AATTATAGTC TAATTGATAA ACATTTGAAT TTATCAGCAA AAAAGAAAGA CTCACATTTA 
CAAGAGGCAG ATATCCAAGT AGAGCAGAAC CGGCAACACT TCTATGAACT GTCTCTCGAG 
TATGTGTGTA AGCTGCAGGA AATCCAAGAA AGAAAGAAGT TTGAGTTTGT GGAACCTATG 
CTGTCATTTT TTCAGGGGAT GTTTACCTTC TATCATCAGG GCCATGAACT TGCCAAAGAC 
TTCAATCACT ACAAAATGGA ACTACAGATC AACATTCAGA ATACACGGAA TCGATTTGAA 
GGAACAAGGT CAGAAGTGGA AGAGCTCATG AACAAAATCA GACAGAATCC CAAGGACCAC 
AAACGAGCAA GTCAGTTTAC AGCCGAAGGC TACCTGTATG TCCAGGAAAA AAGGCCTGCT 
CCGTTTGGTT CCAGTTGGGT CAAACACTAT TGCATGTATC GAAAAGCAGC AAAGAAGTTC 
AACATGATCC CATTTGAGCA CAGATCTGGA GGGAAACTTG GGGACGGAGA GGTGTTCTTT 
TTGAAAGAAT GTACCAAGAG GCATACTGAC TCCATTGACA GAAGGTTTTG TTTTGACATA 
GAAGCTGCTG ATCGGCCTGG CGTTTCCTTG ACCATGCAGG CATTTTCCGA AGAGGAAAGG 
AAGCAGTGGT TGGAAGCTCT GGGTGGAAAG GAAGCTCTGT CCCATAGTTT TAATACAGCC 
ATCATCCCAA GACCAGAAGG AAATGCACAG TTGGATAAGA TGGGGTTCAC AATTATCAGA 
AAATGCATCA GTGCCGTTGA AACACGAGGT ATAAATGACC AAGGATTGTA CAGAGTTGTG 
GGGGTGAGTT CAAAGGTCCA GAGACTTCTG AGTATGTTGA TGGATGTAAA AACATGCAAT 
GAGGTGGACC TGGAGAATTC TGCAGATTGG GAAGTGAAGA CAATAACAAG TGCCTTGAAA 
CAGTATTTGA GGAGTCTTCC AGAGCCTCTC ATGACCTATG AGTTACATGG AGATTTCATT 
GTTCCAGCCA AAAGCGGCAG CCCAGAATCT CGTGTTAATG CGATCCATTT CTTGGTACAC 
AAACTGCCAG AGAAGAATAA AGAGATGTTG GATATTTTGG TGAAACACTT AACAAATGTT 
TCAAATCACT CCAAGCAGAA CCTGATGACT GTGGCAAACT TAGGAGTGGT GTTTGGACCA 
ACTCTGATGA GGCCACAGGA AGAAACTGTC GCTGCCCTCA TGGACTTGAA GTTTCAGAAT 
ATTGTTGTGG AAATCTTAAT TGAAAACCAT GAAAAGATTT TTCGGACGCC GCCCGATACT 
ACATTCCCTG AGCCCACCTG CCTGTCAGCA TCACCCCCAA ATGCGCCACC AAGGCAGTCG 
AAGAGACAAG GCCAGAGAAC CAAGAGGCCC GTGGCCGTCT ACAATCTTTG TCTGGAGCTG 
GAAGATGGTG ACAATCCTTA CCCTTCCAAG GAGGACACCC CTACCAGCAG TCTGGACTCA 
CTTTCCTCCC CGTCTCCCGT GACTACAGCT GTCCCTGGGC CTCCTGGACC AGACAAAAAC 
CACCTTCTGG CAGATGGAGG GAGCTTTGGA GACTGGGCAT CCACTATCCC AGGCCAGACC 
CGATCGTCTA TGGTCCAGTG GCTTAACCCA CAGTCTCCAA CCACAACAAG CTCCAACTCA 
GCTGTGACAC CTCTTTCACC CGGGTCGTCC CCTTTCCCCT TTTCTCCTCC TGCTACTGTA 
GCGGACAAGC CACCTGAAAG CATCCGCAGT CGGAAGGCTC GAGCCGTGTA TCCGTGTGAA 
GCAGAACACA GCTCGGAATT ATCTTTTGAA ATAGGAGCAA TTTTTGAGGA TGTACAAACC 
TCCAGGGAAC CTGGCTGGCT AGAAGGGACT CTGAACGGCA AGAGGGGGCT GATTCCACAG 
AACTACGTCA AGCTGCTGTA G

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

ARHGAP10 ( XM_005263215.3 ) cDNA ORF clone, Homo sapiens(human) -> XP_005263272.1 Homo sapiens Rho GTPase activating protein 10 (ARHGAP10), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OHu39070
Clone ID Related Accession (Same CDS sequence)	XM_005263215.3
Accession Version	XM_005263215.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2208bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-05
Organism	Homo sapiens(human)
Product	rho GTPase-activating protein 10 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000004.12) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 6, 2016 this sequence version replaced XM_005263215.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGGGCTGC AGCCCCTGGA GTTCAGCGAC TGCTACCTCG ACAGCCCGTG GTTCCGGGAG 
AGGATCCGCG CTCACGAAGC GGAACTCGAG AGGACCAACA AGTTCATCAA AGAGCTCATT 
AAGGACGGGA AGAACCTCAT CGCTGCGACG AAAAGTCTGT CAGTGGCCCA GCGGAAGTTT 
GCTCATTCAC TCAGAGACTT TAAGTTTGAG TTTATCGGTG ATGCTGTGAC AGATGATGAA 
CGATGCATAG ATGCTTCCTT ACGTGAATTT TCAAATTTTT TGAAGAATCT GGAGGAACAG 
AGAGAAATTA TGGCATTAAG TGTAACTGAA ACCCTGATTA AACCCTTGGA AAAATTCAGA 
AAAGAGCAAC TTGGAGCTGT AAAGGAAGAA AAAAAGAAGT TTGACAAAGA GACAGAAAAG 
AATTATAGTC TAATTGATAA ACATTTGAAT TTATCAGCAA AAAAGAAAGA CTCACATTTA 
CAAGAGGCAG ATATCCAAGT AGAGCAGAAC CGGCAACACT TCTATGAACT GTCTCTCGAG 
TATGTGTGTA AGCTGCAGGA AATCCAAGAA AGAAAGAAGT TTGAGTTTGT GGAACCTATG 
CTGTCATTTT TTCAGGGGAT GTTTACCTTC TATCATCAGG GCCATGAACT TGCCAAAGAC 
TTCAATCACT ACAAAATGGA ACTACAGATC AACATTCAGA ATACACGGAA TCGATTTGAA 
GGAACAAGGT CAGAAGTGGA AGAGCTCATG AACAAAATCA GACAGAATCC CAAGGACCAC 
AAACGAGCAA GTCAGTTTAC AGCCGAAGGC TACCTGTATG TCCAGGAAAA AAGGCCTGCT 
CCGTTTGGTT CCAGTTGGGT CAAACACTAT TGCATGTATC GAAAAGCAGC AAAGAAGTTC 
AACATGATCC CATTTGAGCA CAGATCTGGA GGGAAACTTG GGGACGGAGA GGTGTTCTTT 
TTGAAAGAAT GTACCAAGAG GCATACTGAC TCCATTGACA GAAGGTTTTG TTTTGACATA 
GAAGCTGCTG ATCGGCCTGG CGTTTCCTTG ACCATGCAGG CATTTTCCGA AGAGGAAAGG 
AAGCAGTGGT TGGAAGCTCT GGGTGGAAAG GAAGCTCTGT CCCATAGTTT TAATACAGCC 
ATCATCCCAA GACCAGAAGG AAATGCACAG TTGGATAAGA TGGGGTTCAC AATTATCAGA 
AAATGCATCA GTGCCGTTGA AACACGAGGT ATAAATGACC AAGGATTGTA CAGAGTTGTG 
GGGGTGAGTT CAAAGGTCCA GAGACTTCTG AGTATGTTGA TGGATGTAAA AACATGCAAT 
GAGGTGGACC TGGAGAATTC TGCAGATTGG GAAGTGAAGA CAATAACAAG TGCCTTGAAA 
CAGTATTTGA GGAGTCTTCC AGAGCCTCTC ATGACCTATG AGTTACATGG AGATTTCATT 
GTTCCAGCCA AAAGCGGCAG CCCAGAATCT CGTGTTAATG CGATCCATTT CTTGGTACAC 
AAACTGCCAG AGAAGAATAA AGAGATGTTG GATATTTTGG TGAAACACTT AACAAATGTT 
TCAAATCACT CCAAGCAGAA CCTGATGACT GTGGCAAACT TAGGAGTGGT GTTTGGACCA 
ACTCTGATGA GGCCACAGGA AGAAACTGTC GCTGCCCTCA TGGACTTGAA GTTTCAGAAT 
ATTGTTGTGG AAATCTTAAT TGAAAACCAT GAAAAGATTT TTCGGACGCC GCCCGATACT 
ACATTCCCTG AGCCCACCTG CCTGTCAGCA TCACCCCCAA ATGCGCCACC AAGGCAGTCG 
AAGAGACAAG GCCAGAGAAC CAAGAGGCCC GTGGCCGTCT ACAATCTTTG TCTGGAGCTG 
GAAGATGGTG ACAATCCTTA CCCTTCCAAG GAGGACACCC CTACCAGCAG TCTGGACTCA 
CTTTCCTCCC CGTCTCCCGT GACTACAGCT GTCCCTGGGC CTCCTGGACC AGACAAAAAC 
CACCTTCTGG CAGATGGAGG GAGCTTTGGA GACTGGGCAT CCACTATCAT CCGCAGTCGG 
AAGGCTCGAG CCGTGTATCC GTGTGAAGCA GAACACAGCT CGGAATTATC TTTTGAAATA 
GGAGCAATTT TTGAGGATGT ACAAACCTCC AGGGAACCTG GCTGGCTAGA AGGGACTCTG 
AACGGCAAGA GGGGGCTGAT TCCACAGAAC TACGTCAAGC TGCTGTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_005263272.1
CDS	237..2444
Translation	MGLQPLEFSDCYLDSPWFRERIRAHEAELERTNKFIKELIKDGKNLIAATKSLSVAQRKFAHSLRDFKFEFIGDAVTDDERCIDASLREFSNFLKNLEEQREIMALSVTETLIKPLEKFRKEQLGAVKEEKKKFDKETEKNYSLIDKHLNLSAKKKDSHLQEADIQVEQNRQHFYELSLEYVCKLQEIQERKKFEFVEPMLSFFQGMFTFYHQGHELAKDFNHYKMELQINIQNTRNRFEGTRSEVEELMNKIRQNPKDHKRASQFTAEGYLYVQEKRPAPFGSSWVKHYCMYRKAAKKFNMIPFEHRSGGKLGDGEVFFLKECTKRHTDSIDRRFCFDIEAADRPGVSLTMQAFSEEERKQWLEALGGKEALSHSFNTAIIPRPEGNAQLDKMGFTIIRKCISAVETRGINDQGLYRVVGVSSKVQRLLSMLMDVKTCNEVDLENSADWEVKTITSALKQYLRSLPEPLMTYELHGDFIVPAKSGSPESRVNAIHFLVHKLPEKNKEMLDILVKHLTNVSNHSKQNLMTVANLGVVFGPTLMRPQEETVAALMDLKFQNIVVEILIENHEKIFRTPPDTTFPEPTCLSASPPNAPPRQSKRQGQRTKRPVAVYNLCLELEDGDNPYPSKEDTPTSSLDSLSSPSPVTTAVPGPPGPDKNHLLADGGSFGDWASTIIRSRKARAVYPCEAEHSSELSFEIGAIFEDVQTSREPGWLEGTLNGKRGLIPQNYVKLL

Target ORF information:

RefSeq Version	XM_005263215.3
Organism	Homo sapiens(human)
Definition	Homo sapiens Rho GTPase activating protein 10 (ARHGAP10), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_005263215.3

ORF Insert Sequence:

ATGGGGCTGC AGCCCCTGGA GTTCAGCGAC TGCTACCTCG ACAGCCCGTG GTTCCGGGAG 
AGGATCCGCG CTCACGAAGC GGAACTCGAG AGGACCAACA AGTTCATCAA AGAGCTCATT 
AAGGACGGGA AGAACCTCAT CGCTGCGACG AAAAGTCTGT CAGTGGCCCA GCGGAAGTTT 
GCTCATTCAC TCAGAGACTT TAAGTTTGAG TTTATCGGTG ATGCTGTGAC AGATGATGAA 
CGATGCATAG ATGCTTCCTT ACGTGAATTT TCAAATTTTT TGAAGAATCT GGAGGAACAG 
AGAGAAATTA TGGCATTAAG TGTAACTGAA ACCCTGATTA AACCCTTGGA AAAATTCAGA 
AAAGAGCAAC TTGGAGCTGT AAAGGAAGAA AAAAAGAAGT TTGACAAAGA GACAGAAAAG 
AATTATAGTC TAATTGATAA ACATTTGAAT TTATCAGCAA AAAAGAAAGA CTCACATTTA 
CAAGAGGCAG ATATCCAAGT AGAGCAGAAC CGGCAACACT TCTATGAACT GTCTCTCGAG 
TATGTGTGTA AGCTGCAGGA AATCCAAGAA AGAAAGAAGT TTGAGTTTGT GGAACCTATG 
CTGTCATTTT TTCAGGGGAT GTTTACCTTC TATCATCAGG GCCATGAACT TGCCAAAGAC 
TTCAATCACT ACAAAATGGA ACTACAGATC AACATTCAGA ATACACGGAA TCGATTTGAA 
GGAACAAGGT CAGAAGTGGA AGAGCTCATG AACAAAATCA GACAGAATCC CAAGGACCAC 
AAACGAGCAA GTCAGTTTAC AGCCGAAGGC TACCTGTATG TCCAGGAAAA AAGGCCTGCT 
CCGTTTGGTT CCAGTTGGGT CAAACACTAT TGCATGTATC GAAAAGCAGC AAAGAAGTTC 
AACATGATCC CATTTGAGCA CAGATCTGGA GGGAAACTTG GGGACGGAGA GGTGTTCTTT 
TTGAAAGAAT GTACCAAGAG GCATACTGAC TCCATTGACA GAAGGTTTTG TTTTGACATA 
GAAGCTGCTG ATCGGCCTGG CGTTTCCTTG ACCATGCAGG CATTTTCCGA AGAGGAAAGG 
AAGCAGTGGT TGGAAGCTCT GGGTGGAAAG GAAGCTCTGT CCCATAGTTT TAATACAGCC 
ATCATCCCAA GACCAGAAGG AAATGCACAG TTGGATAAGA TGGGGTTCAC AATTATCAGA 
AAATGCATCA GTGCCGTTGA AACACGAGGT ATAAATGACC AAGGATTGTA CAGAGTTGTG 
GGGGTGAGTT CAAAGGTCCA GAGACTTCTG AGTATGTTGA TGGATGTAAA AACATGCAAT 
GAGGTGGACC TGGAGAATTC TGCAGATTGG GAAGTGAAGA CAATAACAAG TGCCTTGAAA 
CAGTATTTGA GGAGTCTTCC AGAGCCTCTC ATGACCTATG AGTTACATGG AGATTTCATT 
GTTCCAGCCA AAAGCGGCAG CCCAGAATCT CGTGTTAATG CGATCCATTT CTTGGTACAC 
AAACTGCCAG AGAAGAATAA AGAGATGTTG GATATTTTGG TGAAACACTT AACAAATGTT 
TCAAATCACT CCAAGCAGAA CCTGATGACT GTGGCAAACT TAGGAGTGGT GTTTGGACCA 
ACTCTGATGA GGCCACAGGA AGAAACTGTC GCTGCCCTCA TGGACTTGAA GTTTCAGAAT 
ATTGTTGTGG AAATCTTAAT TGAAAACCAT GAAAAGATTT TTCGGACGCC GCCCGATACT 
ACATTCCCTG AGCCCACCTG CCTGTCAGCA TCACCCCCAA ATGCGCCACC AAGGCAGTCG 
AAGAGACAAG GCCAGAGAAC CAAGAGGCCC GTGGCCGTCT ACAATCTTTG TCTGGAGCTG 
GAAGATGGTG ACAATCCTTA CCCTTCCAAG GAGGACACCC CTACCAGCAG TCTGGACTCA 
CTTTCCTCCC CGTCTCCCGT GACTACAGCT GTCCCTGGGC CTCCTGGACC AGACAAAAAC 
CACCTTCTGG CAGATGGAGG GAGCTTTGGA GACTGGGCAT CCACTATCAT CCGCAGTCGG 
AAGGCTCGAG CCGTGTATCC GTGTGAAGCA GAACACAGCT CGGAATTATC TTTTGAAATA 
GGAGCAATTT TTGAGGATGT ACAAACCTCC AGGGAACCTG GCTGGCTAGA AGGGACTCTG 
AACGGCAAGA GGGGGCTGAT TCCACAGAAC TACGTCAAGC TGCTGTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

ARHGAP10 ( XM_017008602.1 ) cDNA ORF clone, Homo sapiens(human) -> XP_016864091.1 Homo sapiens Rho GTPase activating protein 10 (ARHGAP10), transcript variant X2, mRNA.

Price & Availability↑

CloneID	OHu95397
Clone ID Related Accession (Same CDS sequence)	XM_017008602.1
Accession Version	XM_017008602.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2085bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-05
Organism	Homo sapiens(human)
Product	rho GTPase-activating protein 10 isoform X2
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000004.12) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGCAGGAAG AAATAATTAC CTGCGTTTTA AGATTCAGAA ACAAAACACA GCAGCATTTG 
TATAATACCA TACCATATAT GGACGAAGAT ATTTCTATTC TAAGCTTGGA AGAAAAAAAG 
AAGTTTGACA AAGAGACAGA AAAGAATTAT AGTCTAATTG ATAAACATTT GAATTTATCA 
GCAAAAAAGA AAGACTCACA TTTACAAGAG GCAGATATCC AAGTAGAGCA GAACCGGCAA 
CACTTCTATG AACTGTCTCT CGAGTATGTG TGTAAGCTGC AGGAAATCCA AGAAAGAAAG 
AAGTTTGAGT TTGTGGAACC TATGCTGTCA TTTTTTCAGG GGATGTTTAC CTTCTATCAT 
CAGGGCCATG AACTTGCCAA AGACTTCAAT CACTACAAAA TGGAACTACA GATCAACATT 
CAGAATACAC GGAATCGATT TGAAGGAACA AGGTCAGAAG TGGAAGAGCT CATGAACAAA 
ATCAGACAGA ATCCCAAGGA CCACAAACGA GCAAGTCAGT TTACAGCCGA AGGCTACCTG 
TATGTCCAGG AAAAAAGGCC TGCTCCGTTT GGTTCCAGTT GGGTCAAACA CTATTGCATG 
TATCGAAAAG CAGCAAAGAA GTTCAACATG ATCCCATTTG AGCACAGATC TGGAGGGAAA 
CTTGGGGACG GAGAGGTGTT CTTTTTGAAA GAATGTACCA AGAGGCATAC TGACTCCATT 
GACAGAAGGT TTTGTTTTGA CATAGAAGCT GCTGATCGGC CTGGCGTTTC CTTGACCATG 
CAGGCATTTT CCGAAGAGGA AAGGAAGCAG TGGTTGGAAG CTCTGGGTGG AAAGGAAGCT 
CTGTCCCATA GTTTTAATAC AGCCATCATC CCAAGACCAG AAGGAAATGC ACAGTTGGAT 
AAGATGGGGT TCACAATTAT CAGAAAATGC ATCAGTGCCG TTGAAACACG AGGTATAAAT 
GACCAAGGAT TGTACAGAGT TGTGGGGGTG AGTTCAAAGG TCCAGAGACT TCTGAGTATG 
TTGATGGATG TAAAAACATG CAATGAGGTG GACCTGGAGA ATTCTGCAGA TTGGGAAGTG 
AAGACAATAA CAAGTGCCTT GAAACAGTAT TTGAGGAGTC TTCCAGAGCC TCTCATGACC 
TATGAGTTAC ATGGAGATTT CATTGTTCCA GCCAAAAGCG GCAGCCCAGA ATCTCGTGTT 
AATGCGATCC ATTTCTTGGT ACACAAACTG CCAGAGAAGA ATAAAGAGAT GTTGGATATT 
TTGGTGAAAC ACTTAACAAA TGTTTCAAAT CACTCCAAGC AGAACCTGAT GACTGTGGCA 
AACTTAGGAG TGGTGTTTGG ACCAACTCTG ATGAGGCCAC AGGAAGAAAC TGTCGCTGCC 
CTCATGGACT TGAAGTTTCA GAATATTGTT GTGGAAATCT TAATTGAAAA CCATGAAAAG 
ATTTTTCGGA CGCCGCCCGA TACTACATTC CCTGAGCCCA CCTGCCTGTC AGCATCACCC 
CCAAATGCGC CACCAAGGCA GTCGAAGAGA CAAGGCCAGA GAACCAAGAG GCCCGTGGCC 
GTCTACAATC TTTGTCTGGA GCTGGAAGAT GGTGACAATC CTTACCCTTC CAAGGAGGAC 
ACCCCTACCA GCAGTCTGGA CTCACTTTCC TCCCCGTCTC CCGTGACTAC AGCTGTCCCT 
GGGCCTCCTG GACCAGACAA AAACCACCTT CTGGCAGATG GAGGGAGCTT TGGAGACTGG 
GCATCCACTA TCCCAGGCCA GACCCGATCG TCTATGGTCC AGTGGCTTAA CCCACAGTCT 
CCAACCACAA CAAGCTCCAA CTCAGCTGTG ACACCTCTTT CACCCGGGTC GTCCCCTTTC 
CCCTTTTCTC CTCCTGCTAC TGTAGCGGAC AAGCCACCTG AAAGCATCCG CAGTCGGAAG 
GCTCGAGCCG TGTATCCGTG TGAAGCAGAA CACAGCTCGG AATTATCTTT TGAAATAGGA 
GCAATTTTTG AGGATGTACA AACCTCCAGG GAACCTGGCT GGCTAGAAGG GACTCTGAAC 
GGCAAGAGGG GGCTGATTCC ACAGAACTAC GTCAAGCTGC TGTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_016864091.1
CDS	549..2633
Translation	MQEEIITCVLRFRNKTQQHLYNTIPYMDEDISILSLEEKKKFDKETEKNYSLIDKHLNLSAKKKDSHLQEADIQVEQNRQHFYELSLEYVCKLQEIQERKKFEFVEPMLSFFQGMFTFYHQGHELAKDFNHYKMELQINIQNTRNRFEGTRSEVEELMNKIRQNPKDHKRASQFTAEGYLYVQEKRPAPFGSSWVKHYCMYRKAAKKFNMIPFEHRSGGKLGDGEVFFLKECTKRHTDSIDRRFCFDIEAADRPGVSLTMQAFSEEERKQWLEALGGKEALSHSFNTAIIPRPEGNAQLDKMGFTIIRKCISAVETRGINDQGLYRVVGVSSKVQRLLSMLMDVKTCNEVDLENSADWEVKTITSALKQYLRSLPEPLMTYELHGDFIVPAKSGSPESRVNAIHFLVHKLPEKNKEMLDILVKHLTNVSNHSKQNLMTVANLGVVFGPTLMRPQEETVAALMDLKFQNIVVEILIENHEKIFRTPPDTTFPEPTCLSASPPNAPPRQSKRQGQRTKRPVAVYNLCLELEDGDNPYPSKEDTPTSSLDSLSSPSPVTTAVPGPPGPDKNHLLADGGSFGDWASTIPGQTRSSMVQWLNPQSPTTTSSNSAVTPLSPGSSPFPFSPPATVADKPPESIRSRKARAVYPCEAEHSSELSFEIGAIFEDVQTSREPGWLEGTLNGKRGLIPQNYVKLL

Target ORF information:

RefSeq Version	XM_017008602.1
Organism	Homo sapiens(human)
Definition	Homo sapiens Rho GTPase activating protein 10 (ARHGAP10), transcript variant X2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_017008602.1

ORF Insert Sequence:

ATGCAGGAAG AAATAATTAC CTGCGTTTTA AGATTCAGAA ACAAAACACA GCAGCATTTG 
TATAATACCA TACCATATAT GGACGAAGAT ATTTCTATTC TAAGCTTGGA AGAAAAAAAG 
AAGTTTGACA AAGAGACAGA AAAGAATTAT AGTCTAATTG ATAAACATTT GAATTTATCA 
GCAAAAAAGA AAGACTCACA TTTACAAGAG GCAGATATCC AAGTAGAGCA GAACCGGCAA 
CACTTCTATG AACTGTCTCT CGAGTATGTG TGTAAGCTGC AGGAAATCCA AGAAAGAAAG 
AAGTTTGAGT TTGTGGAACC TATGCTGTCA TTTTTTCAGG GGATGTTTAC CTTCTATCAT 
CAGGGCCATG AACTTGCCAA AGACTTCAAT CACTACAAAA TGGAACTACA GATCAACATT 
CAGAATACAC GGAATCGATT TGAAGGAACA AGGTCAGAAG TGGAAGAGCT CATGAACAAA 
ATCAGACAGA ATCCCAAGGA CCACAAACGA GCAAGTCAGT TTACAGCCGA AGGCTACCTG 
TATGTCCAGG AAAAAAGGCC TGCTCCGTTT GGTTCCAGTT GGGTCAAACA CTATTGCATG 
TATCGAAAAG CAGCAAAGAA GTTCAACATG ATCCCATTTG AGCACAGATC TGGAGGGAAA 
CTTGGGGACG GAGAGGTGTT CTTTTTGAAA GAATGTACCA AGAGGCATAC TGACTCCATT 
GACAGAAGGT TTTGTTTTGA CATAGAAGCT GCTGATCGGC CTGGCGTTTC CTTGACCATG 
CAGGCATTTT CCGAAGAGGA AAGGAAGCAG TGGTTGGAAG CTCTGGGTGG AAAGGAAGCT 
CTGTCCCATA GTTTTAATAC AGCCATCATC CCAAGACCAG AAGGAAATGC ACAGTTGGAT 
AAGATGGGGT TCACAATTAT CAGAAAATGC ATCAGTGCCG TTGAAACACG AGGTATAAAT 
GACCAAGGAT TGTACAGAGT TGTGGGGGTG AGTTCAAAGG TCCAGAGACT TCTGAGTATG 
TTGATGGATG TAAAAACATG CAATGAGGTG GACCTGGAGA ATTCTGCAGA TTGGGAAGTG 
AAGACAATAA CAAGTGCCTT GAAACAGTAT TTGAGGAGTC TTCCAGAGCC TCTCATGACC 
TATGAGTTAC ATGGAGATTT CATTGTTCCA GCCAAAAGCG GCAGCCCAGA ATCTCGTGTT 
AATGCGATCC ATTTCTTGGT ACACAAACTG CCAGAGAAGA ATAAAGAGAT GTTGGATATT 
TTGGTGAAAC ACTTAACAAA TGTTTCAAAT CACTCCAAGC AGAACCTGAT GACTGTGGCA 
AACTTAGGAG TGGTGTTTGG ACCAACTCTG ATGAGGCCAC AGGAAGAAAC TGTCGCTGCC 
CTCATGGACT TGAAGTTTCA GAATATTGTT GTGGAAATCT TAATTGAAAA CCATGAAAAG 
ATTTTTCGGA CGCCGCCCGA TACTACATTC CCTGAGCCCA CCTGCCTGTC AGCATCACCC 
CCAAATGCGC CACCAAGGCA GTCGAAGAGA CAAGGCCAGA GAACCAAGAG GCCCGTGGCC 
GTCTACAATC TTTGTCTGGA GCTGGAAGAT GGTGACAATC CTTACCCTTC CAAGGAGGAC 
ACCCCTACCA GCAGTCTGGA CTCACTTTCC TCCCCGTCTC CCGTGACTAC AGCTGTCCCT 
GGGCCTCCTG GACCAGACAA AAACCACCTT CTGGCAGATG GAGGGAGCTT TGGAGACTGG 
GCATCCACTA TCCCAGGCCA GACCCGATCG TCTATGGTCC AGTGGCTTAA CCCACAGTCT 
CCAACCACAA CAAGCTCCAA CTCAGCTGTG ACACCTCTTT CACCCGGGTC GTCCCCTTTC 
CCCTTTTCTC CTCCTGCTAC TGTAGCGGAC AAGCCACCTG AAAGCATCCG CAGTCGGAAG 
GCTCGAGCCG TGTATCCGTG TGAAGCAGAA CACAGCTCGG AATTATCTTT TGAAATAGGA 
GCAATTTTTG AGGATGTACA AACCTCCAGG GAACCTGGCT GGCTAGAAGG GACTCTGAAC 
GGCAAGAGGG GGCTGATTCC ACAGAACTAC GTCAAGCTGC TGTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

ARHGAP10, downregulated in ovarian cancer, suppresses tumorigenicity of ovarian cancer cells.
Cell death & disease7e2157(2016 Mar)
Luo N,Guo J,Chen L,Yang W,Qu X,Cheng Z

Genome-wide analysis of polymorphisms associated with cytokine responses in smallpox vaccine recipients.
Human genetics131(9)1403-21(2012 Sep)
Kennedy RB,Ovsyannikova IG,Pankratz VS,Haralambieva IH,Vierkant RA,Poland GA

A genome-wide association study of prognosis in breast cancer.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology19(4)1140-3(2010 Apr)
Azzato EM,Pharoah PD,Harrington P,Easton DF,Greenberg D,Caporaso NE,Chanock SJ,Hoover RN,Thomas G,Hunter DJ,Kraft P

A genomewide association study of nicotine and alcohol dependence in Australian and Dutch populations.
Twin research and human genetics : the official journal of the International Society for Twin Studies13(1)10-29(2010 Feb)
Lind PA,Macgregor S,Vink JM,Pergadia ML,Hansell NK,de Moor MH,Smit AB,Hottenga JJ,Richter MM,Heath AC,Martin NG,Willemsen G,de Geus EJ,Vogelzangs N,Penninx BW,Whitfield JB,Montgomery GW,Boomsma DI,Madden PA

A genome-wide association scan of RR and QT interval duration in 3 European genetically isolated populations: the EUROSPAN project.
Circulation. Cardiovascular genetics2(4)322-8(2009 Aug)
Marroni F,Pfeufer A,Aulchenko YS,Franklin CS,Isaacs A,Pichler I,Wild SH,Oostra BA,Wright AF,Campbell H,Witteman JC,K??b S,Hicks AA,Gyllensten U,Rudan I,Meitinger T,Pattaro C,van Duijn CM,Wilson JF,Pramstaller PP,

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ARHGAP10 cDNA ORF clone, Homo sapiens(human)

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