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ASB13 cDNA ORF clone, Homo sapiens(human)

Summary

Gene Symbol ASB13
Entrez Gene ID 79754
Full Name ankyrin repeat and SOCS box containing 13
General protein information
Preferred Names

ankyrin repeat and SOCS box containing 13

Names

ankyrin repeat and SOCS box protein 13
ankyrin repeat domain-containing SOCS box protein Asb-13
Gene Type protein-coding
Organism Homo sapiens(human)
Genome

10

10p15.1
Summary The protein encoded by this gene is a member of the ankyrin repeat and SOCS box-containing (ASB) family of proteins. They contain ankyrin repeat sequence and a SOCS box domain. The SOCS box serves to couple suppressor of cytokine signalling (SOCS) proteins and their binding partners with the elongin B and C complex, possibly targeting them for degradation. Multiple alternatively spliced transcript variants, both protein-coding and not protein-coding, have been described for this gene. [provided by RefSeq, Nov 2010].
Disorder MIM:

615055


Reference Sequences (RefSeq)

mRNA and Protein(s)

mRNA Protein Name
NM_024701.4 NP_078977.2 ankyrin repeat and SOCS box protein 13
NM_024701.3 NP_078977.2 ankyrin repeat and SOCS box protein 13

Pathways from BioSystems


Homologies


Bos taurus (cattle) ASB13 NP_001179710.1
Danio rerio (zebrafish) asb13b XP_684802.4
Xenopus tropicalis (tropical clawed frog) asb13 XP_002931896.1
Mus musculus (house mouse) Asb13 NP_840068.1
Gallus gallus (chicken) ASB13 NP_001186223.1
ASB13 XP_001104985.1
Homo sapiens (human) ASB13 NP_078977.2
Pan troglodytes (chimpanzee) ASB13 XP_001145055.1
Canis lupus familiaris (dog) ASB13 XP_005617233.1
Rattus norvegicus (Norway rat) Asb13 NP_001101890.1

Gene Ontology


Bibliography

Related articles in PubMed

Genome-wide association study combining pathway analysis for typical sporadic amyotrophic lateral sclerosis in Chinese Han populations.
Xie T, Deng L, Mei P, Zhou Y, Wang B, Zhang J, Lin J, Wei Y, Zhang X, Xu R
Neurobiology of aging35(7)1778.e9-1778.e23(2014 Jul)

ASB proteins interact with Cullin5 and Rbx2 to form E3 ubiquitin ligase complexes.
Kohroki J, Nishiyama T, Nakamura T, Masuho Y
FEBS letters579(30)6796-802(2005 Dec)

The SOCS box: a tale of destruction and degradation.
Kile BT, Schulman BA, Alexander WS, Nicola NA, Martin HM, Hilton DJ
Trends in biochemical sciences27(5)235-41(2002 May)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Observational study of gene-disease association. (HuGE Navigator)
Title: An approach based on a genome-wide association study reveals candidate loci for narcolepsy.

The following ASB13 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the ASB13 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID Accession No. Definition **Vector *Turnaround time Price (USD) Select
OHu04192 NM_024701.4
Latest version!		 Homo sapiens ankyrin repeat and SOCS box containing 13 (ASB13), transcript variant 1, mRNA. pcDNA3.1-C-(k)DYK or customized vector
in pcDNA3.1-C-(k)DYK 		$154.50-$216.30
$309.00
View Old Accession Versions >>
OHu04192 NM_024701.3 Homo sapiens ankyrin repeat and SOCS box containing 13 (ASB13), transcript variant 1, mRNA. pcDNA3.1-C-(k)DYK or customized vector
in pcDNA3.1-C-(k)DYK 		$154.50-$216.30
$309.00
Hide Old Accession Versions >>

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)


CloneID OHu04192
Clone ID Related Accession (Same CDS sequence) NM_024701.4 , NM_024701.3
Accession Version NM_024701.4 Latest version! Documents for ORF clone product in default vector
Sequence Information ORF Nucleotide Sequence (Length: 837bp)
Protein sequence
SNP
Vector pcDNA3.1-C-(k)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ™ Seamless cloning technology
Insert Structure linear
Update Date 2019-09-27
Organism Homo sapiens(human)
Product ankyrin repeat and SOCS box protein 13
Comment Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from BP249999.1, AK292071.1, AF403031.1 and AI377400.1. On Nov 23, 2018 this sequence version replaced NM_024701.3. Transcript Variant: This variant (1) represents the protein-coding transcript. ##Evidence-Data-START## Transcript exon combination :: SRR1660803.164679.1, SRR1660803.203968.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2142348, SAMEA2142680 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000357700.11/ ENSP00000350331.6 RefSeq Select criteria :: based on single protein-coding transcript ##RefSeq-Attributes-END## COMPLETENESS: full length. 

1
61
121
181
241
301
361
421
481
541
601
661
721
781
ATGGAGCCCC GGGCGGCGGA CGGCTGCTTC CTGGGCGACG TGGGTTTCTG GGTGGAGCGG 
ACCCCTGTGC ACGAGGCAGC CCAGCGGGGT GAGAGCCTGC AGCTGCAACA GCTGATCGAG 
AGCGGCGCCT GCGTGAACCA GGTCACCGTG GACTCCATCA CGCCCCTGCA CGCAGCCAGT 
CTGCAGGGCC AGGCGCGGTG TGTGCAGCTG CTGCTGGCGG CTGGGGCCCA GGTGGATGCT 
CGCAACATCG ACGGCAGCAC CCCGCTCTGC GATGCCTGCG CCTCGGGCAG CATCGAGTGT 
GTGAAGCTCT TGCTGTCCTA CGGGGCCAAG GTCAACCCTC CCCTGTACAC AGCGTCCCCC 
CTGCACGAGG CCTGCATGAG CGGGAGTTCC GAATGTGTGA GGCTTCTTAT TGACGTCGGG 
GCCAATCTGG AAGCGCACGA TTGCCATTTT GGGACCCCTC TGCACGTTGC CTGTGCCCGG 
GAGCATCTGG ACTGTGTCAA AGTGCTGCTC AATGCAGGGG CCAACGTGAA TGCGGCAAAG 
CTTCATGAGA CTGCCCTTCA CCACGCGGCC AAGGTCAAGA ATGTTGACCT CATCGAGATG 
CTTATCGAGT TTGGCGGCAA CATCTACGCC CGGGACAACC GCGGGAAGAA GCCGTCTGAC 
TACACGTGGA GCAGCAGCGC TCCCGCCAAG TGCTTCGAGT ACTACGAAAA GACACCTCTG 
ACTCTGTCAC AGCTCTGCAG GGTGAACTTG AGGAAGGCCA CTGGCGTCCG AGGGCTGGAG 
AAGATTGCCA AGTTAAACAT CCCGCCCCGG CTCATTGATT ACCTCTCCTA CAACTGA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq NP_078977.2
CDS45..881
Translation

Target ORF information:

RefSeq Version NM_024701.4
Organism Homo sapiens(human)
Definition Homo sapiens ankyrin repeat and SOCS box containing 13 (ASB13), transcript variant 1, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
 NM_024701.4

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
ATGGAGCCCC GGGCGGCGGA CGGCTGCTTC CTGGGCGACG TGGGTTTCTG GGTGGAGCGG 
ACCCCTGTGC ACGAGGCAGC CCAGCGGGGT GAGAGCCTGC AGCTGCAACA GCTGATCGAG 
AGCGGCGCCT GCGTGAACCA GGTCACCGTG GACTCCATCA CGCCCCTGCA CGCAGCCAGT 
CTGCAGGGCC AGGCGCGGTG TGTGCAGCTG CTGCTGGCGG CTGGGGCCCA GGTGGATGCT 
CGCAACATCG ACGGCAGCAC CCCGCTCTGC GATGCCTGCG CCTCGGGCAG CATCGAGTGT 
GTGAAGCTCT TGCTGTCCTA CGGGGCCAAG GTCAACCCTC CCCTGTACAC AGCGTCCCCC 
CTGCACGAGG CCTGCATGAG CGGGAGTTCC GAATGTGTGA GGCTTCTTAT TGACGTCGGG 
GCCAATCTGG AAGCGCACGA TTGCCATTTT GGGACCCCTC TGCACGTTGC CTGTGCCCGG 
GAGCATCTGG ACTGTGTCAA AGTGCTGCTC AATGCAGGGG CCAACGTGAA TGCGGCAAAG 
CTTCATGAGA CTGCCCTTCA CCACGCGGCC AAGGTCAAGA ATGTTGACCT CATCGAGATG 
CTTATCGAGT TTGGCGGCAA CATCTACGCC CGGGACAACC GCGGGAAGAA GCCGTCTGAC 
TACACGTGGA GCAGCAGCGC TCCCGCCAAG TGCTTCGAGT ACTACGAAAA GACACCTCTG 
ACTCTGTCAC AGCTCTGCAG GGTGAACTTG AGGAAGGCCA CTGGCGTCCG AGGGCTGGAG 
AAGATTGCCA AGTTAAACAT CCCGCCCCGG CTCATTGATT ACCTCTCCTA CAACTGA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OHu04192
Clone ID Related Accession (Same CDS sequence) NM_024701.4 , NM_024701.3
Accession Version NM_024701.3 Documents for ORF clone product in default vector
Sequence Information ORF Nucleotide Sequence (Length: 837bp)
Protein sequence
SNP
Vector pcDNA3.1-C-(k)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ™ Seamless cloning technology
Insert Structure linear
Update Date 2017-12-26
Organism Homo sapiens(human)
Product ankyrin repeat and SOCS box protein 13
Comment Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from BP249999.1, AK292071.1, AF403031.1 and AI377400.1. On Dec 13, 2008 this sequence version replaced NM_024701.2. Transcript Variant: This variant (1) represents the protein-coding transcript. ##Evidence-Data-START## Transcript exon combination :: SRR1660803.164679.1, SRR1660803.203968.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2142348, SAMEA2142680 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end. 

1
61
121
181
241
301
361
421
481
541
601
661
721
781
ATGGAGCCCC GGGCGGCGGA CGGCTGCTTC CTGGGCGACG TGGGTTTCTG GGTGGAGCGG 
ACCCCTGTGC ACGAGGCAGC CCAGCGGGGT GAGAGCCTGC AGCTGCAACA GCTGATCGAG 
AGCGGCGCCT GCGTGAACCA GGTCACCGTG GACTCCATCA CGCCCCTGCA CGCAGCCAGT 
CTGCAGGGCC AGGCGCGGTG TGTGCAGCTG CTGCTGGCGG CTGGGGCCCA GGTGGATGCT 
CGCAACATCG ACGGCAGCAC CCCGCTCTGC GATGCCTGCG CCTCGGGCAG CATCGAGTGT 
GTGAAGCTCT TGCTGTCCTA CGGGGCCAAG GTCAACCCTC CCCTGTACAC AGCGTCCCCC 
CTGCACGAGG CCTGCATGAG CGGGAGTTCC GAATGTGTGA GGCTTCTTAT TGACGTCGGG 
GCCAATCTGG AAGCGCACGA TTGCCATTTT GGGACCCCTC TGCACGTTGC CTGTGCCCGG 
GAGCATCTGG ACTGTGTCAA AGTGCTGCTC AATGCAGGGG CCAACGTGAA TGCGGCAAAG 
CTTCATGAGA CTGCCCTTCA CCACGCGGCC AAGGTCAAGA ATGTTGACCT CATCGAGATG 
CTTATCGAGT TTGGCGGCAA CATCTACGCC CGGGACAACC GCGGGAAGAA GCCGTCTGAC 
TACACGTGGA GCAGCAGCGC TCCCGCCAAG TGCTTCGAGT ACTACGAAAA GACACCTCTG 
ACTCTGTCAC AGCTCTGCAG GGTGAACTTG AGGAAGGCCA CTGGCGTCCG AGGGCTGGAG 
AAGATTGCCA AGTTAAACAT CCCGCCCCGG CTCATTGATT ACCTCTCCTA CAACTGA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq NP_078977.2
CDS45..881
Translation

Target ORF information:

RefSeq Version NM_024701.3
Organism Homo sapiens(human)
Definition Homo sapiens ankyrin repeat and SOCS box containing 13 (ASB13), transcript variant 1, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
 NM_024701.3

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
ATGGAGCCCC GGGCGGCGGA CGGCTGCTTC CTGGGCGACG TGGGTTTCTG GGTGGAGCGG 
ACCCCTGTGC ACGAGGCAGC CCAGCGGGGT GAGAGCCTGC AGCTGCAACA GCTGATCGAG 
AGCGGCGCCT GCGTGAACCA GGTCACCGTG GACTCCATCA CGCCCCTGCA CGCAGCCAGT 
CTGCAGGGCC AGGCGCGGTG TGTGCAGCTG CTGCTGGCGG CTGGGGCCCA GGTGGATGCT 
CGCAACATCG ACGGCAGCAC CCCGCTCTGC GATGCCTGCG CCTCGGGCAG CATCGAGTGT 
GTGAAGCTCT TGCTGTCCTA CGGGGCCAAG GTCAACCCTC CCCTGTACAC AGCGTCCCCC 
CTGCACGAGG CCTGCATGAG CGGGAGTTCC GAATGTGTGA GGCTTCTTAT TGACGTCGGG 
GCCAATCTGG AAGCGCACGA TTGCCATTTT GGGACCCCTC TGCACGTTGC CTGTGCCCGG 
GAGCATCTGG ACTGTGTCAA AGTGCTGCTC AATGCAGGGG CCAACGTGAA TGCGGCAAAG 
CTTCATGAGA CTGCCCTTCA CCACGCGGCC AAGGTCAAGA ATGTTGACCT CATCGAGATG 
CTTATCGAGT TTGGCGGCAA CATCTACGCC CGGGACAACC GCGGGAAGAA GCCGTCTGAC 
TACACGTGGA GCAGCAGCGC TCCCGCCAAG TGCTTCGAGT ACTACGAAAA GACACCTCTG 
ACTCTGTCAC AGCTCTGCAG GGTGAACTTG AGGAAGGCCA CTGGCGTCCG AGGGCTGGAG 
AAGATTGCCA AGTTAAACAT CCCGCCCCGG CTCATTGATT ACCTCTCCTA CAACTGA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

PubMed

book

Genome-wide association study combining pathway analysis for typical sporadic amyotrophic lateral sclerosis in Chinese Han populations.
Neurobiology of aging35(7)1778.e9-1778.e23(2014 Jul)
Xie T,Deng L,Mei P,Zhou Y,Wang B,Zhang J,Lin J,Wei Y,Zhang X,Xu R


book

ASB proteins interact with Cullin5 and Rbx2 to form E3 ubiquitin ligase complexes.
FEBS letters579(30)6796-802(2005 Dec)
Kohroki J,Nishiyama T,Nakamura T,Masuho Y


book

The SOCS box: a tale of destruction and degradation.
Trends in biochemical sciences27(5)235-41(2002 May)
Kile BT,Schulman BA,Alexander WS,Nicola NA,Martin HM,Hilton DJ