LRRTM4 cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Gene Symbol	LRRTM4
Entrez Gene ID	80059
Full Name	leucine rich repeat transmembrane neuronal 4
General protein information	Preferred Names leucine rich repeat transmembrane neuronal 4 Names leucine-rich repeat transmembrane neuronal protein 4
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 2 Map Location: 2p12
Disorder MIM:	610870

mRNA and Protein(s)

mRNA	Protein	Name
NM_024993.5	NP_079269.4	leucine-rich repeat transmembrane neuronal protein 4 isoform b precursor
NM_001282928.2	NP_001269857.1	leucine-rich repeat transmembrane neuronal protein 4 isoform c precursor
NM_001282924.2	NP_001269853.1	leucine-rich repeat transmembrane neuronal protein 4 isoform a precursor
NM_024993.4	NP_079269.4	leucine-rich repeat transmembrane neuronal protein 4 isoform b precursor
NM_001330370.1	NP_001317299.1	leucine-rich repeat transmembrane neuronal protein 4 isoform d precursor
NM_001134745.2	NP_001128217.1	leucine-rich repeat transmembrane neuronal protein 4 isoform a precursor
NM_001282928.3	NP_001269857.1	leucine-rich repeat transmembrane neuronal protein 4 isoform c precursor
NM_024993.6	NP_079269.4	leucine-rich repeat transmembrane neuronal protein 4 isoform b precursor

Pathways from BioSystems

Homologies

Homo sapiens (human)	LRRTM4	NP_001128217.1
Mus musculus (house mouse)	Lrrtm4	NP_001128215.1
Gallus gallus (chicken)	LRRTM4	XP_004947696.1
Danio rerio (zebrafish)	lrrtm4	XP_692159.4
Pan troglodytes (chimpanzee)	LRRTM4	XP_001163369.2
	LRRTM4	XP_001112174.2
Canis lupus familiaris (dog)	LRRTM4	XP_005630557.1
Rattus norvegicus (Norway rat)	Lrrtm4	NP_001128218.1
Danio rerio (zebrafish)	LOC100333709	XP_005172519.1
Bos taurus (cattle)	LRRTM4	XP_003586684.1
Xenopus tropicalis (tropical clawed frog)	lrrtm4	XP_002932606.1

Gene Ontology
Bibliography

Related articles in PubMed

Unbiased discovery of glypican as a receptor for LRRTM4 in regulating excitatory synapse development.
de Wit J, O'Sullivan ML, Savas JN, Condomitti G, Caccese MC, Vennekens KM, Yates JR 3rd, Ghosh A
Neuron79(4)696-711(2013 Aug)

A novel gene family encoding leucine-rich repeat transmembrane proteins differentially expressed in the nervous system.
Laur?n J, Airaksinen MS, Saarma M, Timmusk T
Genomics81(4)411-21(2003 Apr)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Clinical trial of gene-disease association and gene-environment interaction. (HuGE Navigator)
Title: Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score.

The following LRRTM4 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the LRRTM4 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

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***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu04308	NM_024993.6 Latest version!	Homo sapiens leucine rich repeat transmembrane neuronal 4 (LRRTM4), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$219.50-$307.30 $439.00
OHu07998	NM_001282928.3 Latest version!	Homo sapiens leucine rich repeat transmembrane neuronal 4 (LRRTM4), transcript variant 4, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5-7	$307.30 $439.00
OHu07189	NM_001282924.2 Latest version!	Homo sapiens leucine rich repeat transmembrane neuronal 4 (LRRTM4), transcript variant 3, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$307.30 $439.00
OHu07189	NM_001134745.2 Latest version!	Homo sapiens leucine rich repeat transmembrane neuronal 4 (LRRTM4), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$307.30 $439.00
OHu72524	NM_001330370.1 Latest version!	Homo sapiens leucine rich repeat transmembrane neuronal 4 (LRRTM4), transcript variant 5, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$307.30 $439.00
View Old Accession Versions >>
OHu04308	NM_024993.4	Homo sapiens leucine rich repeat transmembrane neuronal 4 (LRRTM4), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$219.50-$307.30 $439.00
OHu07998	NM_001282928.2	Homo sapiens leucine rich repeat transmembrane neuronal 4 (LRRTM4), transcript variant 4, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5-7	$307.30 $439.00
OHu04308	NM_024993.5	Homo sapiens leucine rich repeat transmembrane neuronal 4 (LRRTM4), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$219.50-$307.30 $439.00
Hide Old Accession Versions >>

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

LRRTM4 ( NM_024993.5 ) cDNA ORF clone, Homo sapiens(human) -> NP_079269.4 Homo sapiens leucine rich repeat transmembrane neuronal 4 (LRRTM4), transcript variant 2, mRNA.

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CloneID	OHu04308
Clone ID Related Accession (Same CDS sequence)	NM_024993.5 , NM_024993.4 , NM_024993.6
Accession Version	NM_024993.5	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1557bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-02-25
Organism	Homo sapiens(human)
Product	leucine-rich repeat transmembrane neuronal protein 4 isoform b precursor
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AC079614.7. On Aug 29, 2016 this sequence version replaced NM_024993.4. Transcript Variant: This variant (2) lacks the 3' terminal exon and its transcription extends past a splice site that is used in variant 1, resulting in a novel 3' coding region and 3' UTR compared to variant 1. It encodes isoform b which is shorter and has a distinct C-terminus, compared to isoform a. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. ##Evidence-Data-START## Transcript exon combination :: AK126961.1, SRR1803616.222453.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2145743, SAMEA2154665 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGGTTTCC ATTTAATTAC GCAGCTGAAA GGCATGAGTG TGGTGCTGGT GCTACTTCCT 
ACACTGCTGC TTGTTATGCT CACGGGTGCT CAGAGAGCTT GCCCAAAGAA CTGCAGATGT 
GATGGCAAAA TTGTGTACTG TGAGTCTCAT GCTTTCGCAG ATATCCCTGA GAACATTTCT 
GGAGGGTCAC AAGGCTTATC ATTAAGGTTC AACAGCATTC AGAAGCTCAA ATCCAATCAG 
TTTGCCGGCC TTAACCAGCT TATATGGCTT TATCTTGACC ATAATTACAT TAGCTCAGTG 
GATGAAGATG CATTTCAAGG GATCCGTAGA CTGAAAGAAT TAATTCTAAG CTCCAACAAA 
ATTACTTATC TGCACAATAA AACATTTCAC CCAGTTCCCA ATCTCCGCAA TCTGGACCTC 
TCCTACAATA AGCTTCAGAC ATTGCAATCT GAACAATTTA AAGGCCTTCG GAAACTCATC 
ATTTTGCACT TGAGATCTAA CTCACTAAAG ACTGTGCCCA TAAGAGTTTT TCAAGACTGT 
CGGAATCTTG ATTTTTTGGA TTTGGGTTAC AATCGTCTTC GAAGCTTGTC CCGAAATGCA 
TTTGCTGGCC TCTTGAAGTT AAAGGAGCTC CACCTGGAGC ACAACCAGTT TTCCAAGATC 
AACTTTGCTC ATTTTCCACG TCTCTTCAAC CTCCGCTCAA TTTACTTACA ATGGAACAGG 
ATTCGCTCCA TTAGCCAAGG TTTGACATGG ACTTGGAGTT CCTTACACAA CTTGGATTTA 
TCAGGGAATG ACATCCAAGG AATTGAGCCG GGCACATTTA AATGCCTCCC CAATTTACAA 
AAATTGAATT TGGATTCCAA CAAGCTCACC AATATCTCAC AGGAAACTGT CAATGCGTGG 
ATATCATTAA TATCCATCAC ATTGTCTGGA AATATGTGGG AATGCAGTCG GAGCATTTGT 
CCTTTATTTT ATTGGCTTAA GAATTTCAAA GGAAATAAGG AAAGCACCAT GATATGTGCG 
GGACCTAAGC ACATCCAGGG TGAAAAGGTT AGTGATGCAG TGGAAACATA TAATATCTGT 
TCTGAAGTCC AGGTGGTCAA CACAGAAAGA TCACACCTGG TGCCCCAAAC TCCCCAGAAA 
CCTCTGATTA TCCCTAGACC TACCATCTTC AAACCTGACG TCACCCAATC CACCTTTGAA 
ACACCAAGCC CTTCCCCAGG GTTTCAGATT CCTGGCGCAG AGCAAGAGTA TGAGCATGTT 
TCATTTCACA AAATTATTGC CGGGAGTGTG GCTCTCTTTC TCTCAGTGGC CATGATCCTC 
TTGGTGATCT ATGTGTCTTG GAAACGCTAC CCAGCCAGCA TGAAACAACT CCAGCAACAC 
TCTCTTATGA AGAGGCGGCG GAAAAAGGCC AGAGAGTCTG AAAGACAAAT GAATTCCCCT 
TTACAGGAGT ATTATGTGGA CTACAAGCCT ACAAACTCTG AGACCATGGA TATATCGGTT 
AATGGATCTG GGCCCTGCAC ATATACCATC TCTGGCTCCA GGGAATGTGA GGTATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_079269.4
CDS	473..2029
Translation	MGFHLITQLKGMSVVLVLLPTLLLVMLTGAQRACPKNCRCDGKIVYCESHAFADIPENISGGSQGLSLRFNSIQKLKSNQFAGLNQLIWLYLDHNYISSVDEDAFQGIRRLKELILSSNKITYLHNKTFHPVPNLRNLDLSYNKLQTLQSEQFKGLRKLIILHLRSNSLKTVPIRVFQDCRNLDFLDLGYNRLRSLSRNAFAGLLKLKELHLEHNQFSKINFAHFPRLFNLRSIYLQWNRIRSISQGLTWTWSSLHNLDLSGNDIQGIEPGTFKCLPNLQKLNLDSNKLTNISQETVNAWISLISITLSGNMWECSRSICPLFYWLKNFKGNKESTMICAGPKHIQGEKVSDAVETYNICSEVQVVNTERSHLVPQTPQKPLIIPRPTIFKPDVTQSTFETPSPSPGFQIPGAEQEYEHVSFHKIIAGSVALFLSVAMILLVIYVSWKRYPASMKQLQQHSLMKRRRKKARESERQMNSPLQEYYVDYKPTNSETMDISVNGSGPCTYTISGSRECEV

Target ORF information:

RefSeq Version	NM_024993.5
Organism	Homo sapiens(human)
Definition	Homo sapiens leucine rich repeat transmembrane neuronal 4 (LRRTM4), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_024993.5

ORF Insert Sequence:

ATGGGTTTCC ATTTAATTAC GCAGCTGAAA GGCATGAGTG TGGTGCTGGT GCTACTTCCT 
ACACTGCTGC TTGTTATGCT CACGGGTGCT CAGAGAGCTT GCCCAAAGAA CTGCAGATGT 
GATGGCAAAA TTGTGTACTG TGAGTCTCAT GCTTTCGCAG ATATCCCTGA GAACATTTCT 
GGAGGGTCAC AAGGCTTATC ATTAAGGTTC AACAGCATTC AGAAGCTCAA ATCCAATCAG 
TTTGCCGGCC TTAACCAGCT TATATGGCTT TATCTTGACC ATAATTACAT TAGCTCAGTG 
GATGAAGATG CATTTCAAGG GATCCGTAGA CTGAAAGAAT TAATTCTAAG CTCCAACAAA 
ATTACTTATC TGCACAATAA AACATTTCAC CCAGTTCCCA ATCTCCGCAA TCTGGACCTC 
TCCTACAATA AGCTTCAGAC ATTGCAATCT GAACAATTTA AAGGCCTTCG GAAACTCATC 
ATTTTGCACT TGAGATCTAA CTCACTAAAG ACTGTGCCCA TAAGAGTTTT TCAAGACTGT 
CGGAATCTTG ATTTTTTGGA TTTGGGTTAC AATCGTCTTC GAAGCTTGTC CCGAAATGCA 
TTTGCTGGCC TCTTGAAGTT AAAGGAGCTC CACCTGGAGC ACAACCAGTT TTCCAAGATC 
AACTTTGCTC ATTTTCCACG TCTCTTCAAC CTCCGCTCAA TTTACTTACA ATGGAACAGG 
ATTCGCTCCA TTAGCCAAGG TTTGACATGG ACTTGGAGTT CCTTACACAA CTTGGATTTA 
TCAGGGAATG ACATCCAAGG AATTGAGCCG GGCACATTTA AATGCCTCCC CAATTTACAA 
AAATTGAATT TGGATTCCAA CAAGCTCACC AATATCTCAC AGGAAACTGT CAATGCGTGG 
ATATCATTAA TATCCATCAC ATTGTCTGGA AATATGTGGG AATGCAGTCG GAGCATTTGT 
CCTTTATTTT ATTGGCTTAA GAATTTCAAA GGAAATAAGG AAAGCACCAT GATATGTGCG 
GGACCTAAGC ACATCCAGGG TGAAAAGGTT AGTGATGCAG TGGAAACATA TAATATCTGT 
TCTGAAGTCC AGGTGGTCAA CACAGAAAGA TCACACCTGG TGCCCCAAAC TCCCCAGAAA 
CCTCTGATTA TCCCTAGACC TACCATCTTC AAACCTGACG TCACCCAATC CACCTTTGAA 
ACACCAAGCC CTTCCCCAGG GTTTCAGATT CCTGGCGCAG AGCAAGAGTA TGAGCATGTT 
TCATTTCACA AAATTATTGC CGGGAGTGTG GCTCTCTTTC TCTCAGTGGC CATGATCCTC 
TTGGTGATCT ATGTGTCTTG GAAACGCTAC CCAGCCAGCA TGAAACAACT CCAGCAACAC 
TCTCTTATGA AGAGGCGGCG GAAAAAGGCC AGAGAGTCTG AAAGACAAAT GAATTCCCCT 
TTACAGGAGT ATTATGTGGA CTACAAGCCT ACAAACTCTG AGACCATGGA TATATCGGTT 
AATGGATCTG GGCCCTGCAC ATATACCATC TCTGGCTCCA GGGAATGTGA GGTATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

LRRTM4 ( NM_024993.4 ) cDNA ORF clone, Homo sapiens(human) -> NP_079269.4 Homo sapiens leucine rich repeat transmembrane neuronal 4 (LRRTM4), transcript variant 2, mRNA.

Price & Availability↑

CloneID	OHu04308
Clone ID Related Accession (Same CDS sequence)	NM_024993.5 , NM_024993.4 , NM_024993.6
Accession Version	NM_024993.4	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1557bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2015-03-14
Organism	Homo sapiens(Human)
Product	leucine-rich repeat transmembrane neuronal protein 4 isoform b precursor
Comment

ATGGGTTTCC ATTTAATTAC GCAGCTGAAA GGCATGAGTG TGGTGCTGGT GCTACTTCCT 
ACACTGCTGC TTGTTATGCT CACGGGTGCT CAGAGAGCTT GCCCAAAGAA CTGCAGATGT 
GATGGCAAAA TTGTGTACTG TGAGTCTCAT GCTTTCGCAG ATATCCCTGA GAACATTTCT 
GGAGGGTCAC AAGGCTTATC ATTAAGGTTC AACAGCATTC AGAAGCTCAA ATCCAATCAG 
TTTGCCGGCC TTAACCAGCT TATATGGCTT TATCTTGACC ATAATTACAT TAGCTCAGTG 
GATGAAGATG CATTTCAAGG GATCCGTAGA CTGAAAGAAT TAATTCTAAG CTCCAACAAA 
ATTACTTATC TGCACAATAA AACATTTCAC CCAGTTCCCA ATCTCCGCAA TCTGGACCTC 
TCCTACAATA AGCTTCAGAC ATTGCAATCT GAACAATTTA AAGGCCTTCG GAAACTCATC 
ATTTTGCACT TGAGATCTAA CTCACTAAAG ACTGTGCCCA TAAGAGTTTT TCAAGACTGT 
CGGAATCTTG ATTTTTTGGA TTTGGGTTAC AATCGTCTTC GAAGCTTGTC CCGAAATGCA 
TTTGCTGGCC TCTTGAAGTT AAAGGAGCTC CACCTGGAGC ACAACCAGTT TTCCAAGATC 
AACTTTGCTC ATTTTCCACG TCTCTTCAAC CTCCGCTCAA TTTACTTACA ATGGAACAGG 
ATTCGCTCCA TTAGCCAAGG TTTGACATGG ACTTGGAGTT CCTTACACAA CTTGGATTTA 
TCAGGGAATG ACATCCAAGG AATTGAGCCG GGCACATTTA AATGCCTCCC CAATTTACAA 
AAATTGAATT TGGATTCCAA CAAGCTCACC AATATCTCAC AGGAAACTGT CAATGCGTGG 
ATATCATTAA TATCCATCAC ATTGTCTGGA AATATGTGGG AATGCAGTCG GAGCATTTGT 
CCTTTATTTT ATTGGCTTAA GAATTTCAAA GGAAATAAGG AAAGCACCAT GATATGTGCG 
GGACCTAAGC ACATCCAGGG TGAAAAGGTT AGTGATGCAG TGGAAACATA TAATATCTGT 
TCTGAAGTCC AGGTGGTCAA CACAGAAAGA TCACACCTGG TGCCCCAAAC TCCCCAGAAA 
CCTCTGATTA TCCCTAGACC TACCATCTTC AAACCTGACG TCACCCAATC CACCTTTGAA 
ACACCAAGCC CTTCCCCAGG GTTTCAGATT CCTGGCGCAG AGCAAGAGTA TGAGCATGTT 
TCATTTCACA AAATTATTGC CGGGAGTGTG GCTCTCTTTC TCTCAGTGGC CATGATCCTC 
TTGGTGATCT ATGTGTCTTG GAAACGCTAC CCAGCCAGCA TGAAACAACT CCAGCAACAC 
TCTCTTATGA AGAGGCGGCG GAAAAAGGCC AGAGAGTCTG AAAGACAAAT GAATTCCCCT 
TTACAGGAGT ATTATGTGGA CTACAAGCCT ACAAACTCTG AGACCATGGA TATATCGGTT 
AATGGATCTG GGCCCTGCAC ATATACCATC TCTGGCTCCA GGGAATGTGA GGTATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq

NP_079269.4

Translation

MGFHLITQLKGMSVVLVLLPTLLLVMLTGAQRACPKNCRCDGKIVYCESHAFADIPENISGGSQGLSLRFNSIQKLKSNQFAGLNQLIWLYLDHNYISSVDEDAFQGIRRLKELILSSNKITYLHNKTFHPVPNLRNLDLSYNKLQTLQSEQFKGLRKLIILHLRSNSLKTVPIRVFQDCRNLDFLDLGYNRLRSLSRNAFAGLLKLKELHLEHNQFSKINFAHFPRLFNLRSIYLQWNRIRSISQGLTWTWSSLHNLDLSGNDIQGIEPGTFKCLPNLQKLNLDSNKLTNISQETVNAWISLISITLSGNMWECSRSICPLFYWLKNFKGNKESTMICAGPKHIQGEKVSDAVETYNICSEVQVVNTERSHLVPQTPQKPLIIPRPTIFKPDVTQSTFETPSPSPGFQIPGAEQEYEHVSFHKIIAGSVALFLSVAMILLVIYVSWKRYPASMKQLQQHSLMKRRRKKARESERQMNSPLQEYYVDYKPTNSETMDISVNGSGPCTYTISGSRECEV

Target ORF information:

RefSeq Version	NM_024993.4
Organism	Homo sapiens(Human)
Definition	Homo sapiens leucine rich repeat transmembrane neuronal 4 (LRRTM4), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_024993.4

ORF Insert Sequence:

ATGGGTTTCC ATTTAATTAC GCAGCTGAAA GGCATGAGTG TGGTGCTGGT GCTACTTCCT 
ACACTGCTGC TTGTTATGCT CACGGGTGCT CAGAGAGCTT GCCCAAAGAA CTGCAGATGT 
GATGGCAAAA TTGTGTACTG TGAGTCTCAT GCTTTCGCAG ATATCCCTGA GAACATTTCT 
GGAGGGTCAC AAGGCTTATC ATTAAGGTTC AACAGCATTC AGAAGCTCAA ATCCAATCAG 
TTTGCCGGCC TTAACCAGCT TATATGGCTT TATCTTGACC ATAATTACAT TAGCTCAGTG 
GATGAAGATG CATTTCAAGG GATCCGTAGA CTGAAAGAAT TAATTCTAAG CTCCAACAAA 
ATTACTTATC TGCACAATAA AACATTTCAC CCAGTTCCCA ATCTCCGCAA TCTGGACCTC 
TCCTACAATA AGCTTCAGAC ATTGCAATCT GAACAATTTA AAGGCCTTCG GAAACTCATC 
ATTTTGCACT TGAGATCTAA CTCACTAAAG ACTGTGCCCA TAAGAGTTTT TCAAGACTGT 
CGGAATCTTG ATTTTTTGGA TTTGGGTTAC AATCGTCTTC GAAGCTTGTC CCGAAATGCA 
TTTGCTGGCC TCTTGAAGTT AAAGGAGCTC CACCTGGAGC ACAACCAGTT TTCCAAGATC 
AACTTTGCTC ATTTTCCACG TCTCTTCAAC CTCCGCTCAA TTTACTTACA ATGGAACAGG 
ATTCGCTCCA TTAGCCAAGG TTTGACATGG ACTTGGAGTT CCTTACACAA CTTGGATTTA 
TCAGGGAATG ACATCCAAGG AATTGAGCCG GGCACATTTA AATGCCTCCC CAATTTACAA 
AAATTGAATT TGGATTCCAA CAAGCTCACC AATATCTCAC AGGAAACTGT CAATGCGTGG 
ATATCATTAA TATCCATCAC ATTGTCTGGA AATATGTGGG AATGCAGTCG GAGCATTTGT 
CCTTTATTTT ATTGGCTTAA GAATTTCAAA GGAAATAAGG AAAGCACCAT GATATGTGCG 
GGACCTAAGC ACATCCAGGG TGAAAAGGTT AGTGATGCAG TGGAAACATA TAATATCTGT 
TCTGAAGTCC AGGTGGTCAA CACAGAAAGA TCACACCTGG TGCCCCAAAC TCCCCAGAAA 
CCTCTGATTA TCCCTAGACC TACCATCTTC AAACCTGACG TCACCCAATC CACCTTTGAA 
ACACCAAGCC CTTCCCCAGG GTTTCAGATT CCTGGCGCAG AGCAAGAGTA TGAGCATGTT 
TCATTTCACA AAATTATTGC CGGGAGTGTG GCTCTCTTTC TCTCAGTGGC CATGATCCTC 
TTGGTGATCT ATGTGTCTTG GAAACGCTAC CCAGCCAGCA TGAAACAACT CCAGCAACAC 
TCTCTTATGA AGAGGCGGCG GAAAAAGGCC AGAGAGTCTG AAAGACAAAT GAATTCCCCT 
TTACAGGAGT ATTATGTGGA CTACAAGCCT ACAAACTCTG AGACCATGGA TATATCGGTT 
AATGGATCTG GGCCCTGCAC ATATACCATC TCTGGCTCCA GGGAATGTGA GGTATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

LRRTM4 ( NM_024993.6 ) cDNA ORF clone, Homo sapiens(human) -> NP_079269.4 Homo sapiens leucine rich repeat transmembrane neuronal 4 (LRRTM4), transcript variant 2, mRNA.

Price & Availability↑

CloneID	OHu04308
Clone ID Related Accession (Same CDS sequence)	NM_024993.5 , NM_024993.4 , NM_024993.6
Accession Version	NM_024993.6 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1557bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-09-28
Organism	Homo sapiens(human)
Product	leucine-rich repeat transmembrane neuronal protein 4 isoform b precursor
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AC079614.7. On Jun 2, 2019 this sequence version replaced NM_024993.5. Transcript Variant: This variant (2) lacks the 3' terminal exon and its transcription extends past a splice site that is used in variant 1, resulting in a novel 3' coding region and 3' UTR compared to variant 1. It encodes isoform b which is shorter and has a distinct C-terminus, compared to isoform a. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. ##Evidence-Data-START## Transcript exon combination :: AK126961.1, SRR1660803.190778.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2145743, SAMEA2154665 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGGTTTCC ATTTAATTAC GCAGCTGAAA GGCATGAGTG TGGTGCTGGT GCTACTTCCT 
ACACTGCTGC TTGTTATGCT CACGGGTGCT CAGAGAGCTT GCCCAAAGAA CTGCAGATGT 
GATGGCAAAA TTGTGTACTG TGAGTCTCAT GCTTTCGCAG ATATCCCTGA GAACATTTCT 
GGAGGGTCAC AAGGCTTATC ATTAAGGTTC AACAGCATTC AGAAGCTCAA ATCCAATCAG 
TTTGCCGGCC TTAACCAGCT TATATGGCTT TATCTTGACC ATAATTACAT TAGCTCAGTG 
GATGAAGATG CATTTCAAGG GATCCGTAGA CTGAAAGAAT TAATTCTAAG CTCCAACAAA 
ATTACTTATC TGCACAATAA AACATTTCAC CCAGTTCCCA ATCTCCGCAA TCTGGACCTC 
TCCTACAATA AGCTTCAGAC ATTGCAATCT GAACAATTTA AAGGCCTTCG GAAACTCATC 
ATTTTGCACT TGAGATCTAA CTCACTAAAG ACTGTGCCCA TAAGAGTTTT TCAAGACTGT 
CGGAATCTTG ATTTTTTGGA TTTGGGTTAC AATCGTCTTC GAAGCTTGTC CCGAAATGCA 
TTTGCTGGCC TCTTGAAGTT AAAGGAGCTC CACCTGGAGC ACAACCAGTT TTCCAAGATC 
AACTTTGCTC ATTTTCCACG TCTCTTCAAC CTCCGCTCAA TTTACTTACA ATGGAACAGG 
ATTCGCTCCA TTAGCCAAGG TTTGACATGG ACTTGGAGTT CCTTACACAA CTTGGATTTA 
TCAGGGAATG ACATCCAAGG AATTGAGCCG GGCACATTTA AATGCCTCCC CAATTTACAA 
AAATTGAATT TGGATTCCAA CAAGCTCACC AATATCTCAC AGGAAACTGT CAATGCGTGG 
ATATCATTAA TATCCATCAC ATTGTCTGGA AATATGTGGG AATGCAGTCG GAGCATTTGT 
CCTTTATTTT ATTGGCTTAA GAATTTCAAA GGAAATAAGG AAAGCACCAT GATATGTGCG 
GGACCTAAGC ACATCCAGGG TGAAAAGGTT AGTGATGCAG TGGAAACATA TAATATCTGT 
TCTGAAGTCC AGGTGGTCAA CACAGAAAGA TCACACCTGG TGCCCCAAAC TCCCCAGAAA 
CCTCTGATTA TCCCTAGACC TACCATCTTC AAACCTGACG TCACCCAATC CACCTTTGAA 
ACACCAAGCC CTTCCCCAGG GTTTCAGATT CCTGGCGCAG AGCAAGAGTA TGAGCATGTT 
TCATTTCACA AAATTATTGC CGGGAGTGTG GCTCTCTTTC TCTCAGTGGC CATGATCCTC 
TTGGTGATCT ATGTGTCTTG GAAACGCTAC CCAGCCAGCA TGAAACAACT CCAGCAACAC 
TCTCTTATGA AGAGGCGGCG GAAAAAGGCC AGAGAGTCTG AAAGACAAAT GAATTCCCCT 
TTACAGGAGT ATTATGTGGA CTACAAGCCT ACAAACTCTG AGACCATGGA TATATCGGTT 
AATGGATCTG GGCCCTGCAC ATATACCATC TCTGGCTCCA GGGAATGTGA GGTATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_079269.4
CDS	416..1972
Translation	MGFHLITQLKGMSVVLVLLPTLLLVMLTGAQRACPKNCRCDGKIVYCESHAFADIPENISGGSQGLSLRFNSIQKLKSNQFAGLNQLIWLYLDHNYISSVDEDAFQGIRRLKELILSSNKITYLHNKTFHPVPNLRNLDLSYNKLQTLQSEQFKGLRKLIILHLRSNSLKTVPIRVFQDCRNLDFLDLGYNRLRSLSRNAFAGLLKLKELHLEHNQFSKINFAHFPRLFNLRSIYLQWNRIRSISQGLTWTWSSLHNLDLSGNDIQGIEPGTFKCLPNLQKLNLDSNKLTNISQETVNAWISLISITLSGNMWECSRSICPLFYWLKNFKGNKESTMICAGPKHIQGEKVSDAVETYNICSEVQVVNTERSHLVPQTPQKPLIIPRPTIFKPDVTQSTFETPSPSPGFQIPGAEQEYEHVSFHKIIAGSVALFLSVAMILLVIYVSWKRYPASMKQLQQHSLMKRRRKKARESERQMNSPLQEYYVDYKPTNSETMDISVNGSGPCTYTISGSRECEV

Target ORF information:

RefSeq Version	NM_024993.6
Organism	Homo sapiens(human)
Definition	Homo sapiens leucine rich repeat transmembrane neuronal 4 (LRRTM4), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_024993.6

ORF Insert Sequence:

ATGGGTTTCC ATTTAATTAC GCAGCTGAAA GGCATGAGTG TGGTGCTGGT GCTACTTCCT 
ACACTGCTGC TTGTTATGCT CACGGGTGCT CAGAGAGCTT GCCCAAAGAA CTGCAGATGT 
GATGGCAAAA TTGTGTACTG TGAGTCTCAT GCTTTCGCAG ATATCCCTGA GAACATTTCT 
GGAGGGTCAC AAGGCTTATC ATTAAGGTTC AACAGCATTC AGAAGCTCAA ATCCAATCAG 
TTTGCCGGCC TTAACCAGCT TATATGGCTT TATCTTGACC ATAATTACAT TAGCTCAGTG 
GATGAAGATG CATTTCAAGG GATCCGTAGA CTGAAAGAAT TAATTCTAAG CTCCAACAAA 
ATTACTTATC TGCACAATAA AACATTTCAC CCAGTTCCCA ATCTCCGCAA TCTGGACCTC 
TCCTACAATA AGCTTCAGAC ATTGCAATCT GAACAATTTA AAGGCCTTCG GAAACTCATC 
ATTTTGCACT TGAGATCTAA CTCACTAAAG ACTGTGCCCA TAAGAGTTTT TCAAGACTGT 
CGGAATCTTG ATTTTTTGGA TTTGGGTTAC AATCGTCTTC GAAGCTTGTC CCGAAATGCA 
TTTGCTGGCC TCTTGAAGTT AAAGGAGCTC CACCTGGAGC ACAACCAGTT TTCCAAGATC 
AACTTTGCTC ATTTTCCACG TCTCTTCAAC CTCCGCTCAA TTTACTTACA ATGGAACAGG 
ATTCGCTCCA TTAGCCAAGG TTTGACATGG ACTTGGAGTT CCTTACACAA CTTGGATTTA 
TCAGGGAATG ACATCCAAGG AATTGAGCCG GGCACATTTA AATGCCTCCC CAATTTACAA 
AAATTGAATT TGGATTCCAA CAAGCTCACC AATATCTCAC AGGAAACTGT CAATGCGTGG 
ATATCATTAA TATCCATCAC ATTGTCTGGA AATATGTGGG AATGCAGTCG GAGCATTTGT 
CCTTTATTTT ATTGGCTTAA GAATTTCAAA GGAAATAAGG AAAGCACCAT GATATGTGCG 
GGACCTAAGC ACATCCAGGG TGAAAAGGTT AGTGATGCAG TGGAAACATA TAATATCTGT 
TCTGAAGTCC AGGTGGTCAA CACAGAAAGA TCACACCTGG TGCCCCAAAC TCCCCAGAAA 
CCTCTGATTA TCCCTAGACC TACCATCTTC AAACCTGACG TCACCCAATC CACCTTTGAA 
ACACCAAGCC CTTCCCCAGG GTTTCAGATT CCTGGCGCAG AGCAAGAGTA TGAGCATGTT 
TCATTTCACA AAATTATTGC CGGGAGTGTG GCTCTCTTTC TCTCAGTGGC CATGATCCTC 
TTGGTGATCT ATGTGTCTTG GAAACGCTAC CCAGCCAGCA TGAAACAACT CCAGCAACAC 
TCTCTTATGA AGAGGCGGCG GAAAAAGGCC AGAGAGTCTG AAAGACAAAT GAATTCCCCT 
TTACAGGAGT ATTATGTGGA CTACAAGCCT ACAAACTCTG AGACCATGGA TATATCGGTT 
AATGGATCTG GGCCCTGCAC ATATACCATC TCTGGCTCCA GGGAATGTGA GGTATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

LRRTM4 ( NM_001282928.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_001269857.1 Homo sapiens leucine rich repeat transmembrane neuronal 4 (LRRTM4), transcript variant 4, mRNA.

Price & Availability↑

CloneID	OHu07998
Clone ID Related Accession (Same CDS sequence)	NM_001282928.2 , NM_001282928.3
Accession Version	NM_001282928.2	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1560bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2018-06-30
Organism	Homo sapiens(human)
Product	leucine-rich repeat transmembrane neuronal protein 4 isoform c precursor
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AC079614.7, AK122612.1 and BC098301.1. On Aug 29, 2016 this sequence version replaced NM_001282928.1. Transcript Variant: This variant (4) lacks an exon in the 5' region and its transcription extends past a splice site that is used in variant 1, resulting in a novel 3' coding region and 3' UTR. It initiates translation at an alternate start codon compared to variant 1 and encodes isoform c, which distinct N- and C-termini and is shorter than isoform a. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. ##Evidence-Data-START## Transcript exon combination :: SRR1803615.178693.1, SRR1660807.138752.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2154665, SAMEA2157437 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGCCAGGTT TCCATTTAAT TACGCAGCTG AAAGGCATGA GTGTGGTGCT GGTGCTACTT 
CCTACACTGC TGCTTGTTAT GCTCACGGGT GCTCAGAGAG CTTGCCCAAA GAACTGCAGA 
TGTGATGGCA AAATTGTGTA CTGTGAGTCT CATGCTTTCG CAGATATCCC TGAGAACATT 
TCTGGAGGGT CACAAGGCTT ATCATTAAGG TTCAACAGCA TTCAGAAGCT CAAATCCAAT 
CAGTTTGCCG GCCTTAACCA GCTTATATGG CTTTATCTTG ACCATAATTA CATTAGCTCA 
GTGGATGAAG ATGCATTTCA AGGGATCCGT AGACTGAAAG AATTAATTCT AAGCTCCAAC 
AAAATTACTT ATCTGCACAA TAAAACATTT CACCCAGTTC CCAATCTCCG CAATCTGGAC 
CTCTCCTACA ATAAGCTTCA GACATTGCAA TCTGAACAAT TTAAAGGCCT TCGGAAACTC 
ATCATTTTGC ACTTGAGATC TAACTCACTA AAGACTGTGC CCATAAGAGT TTTTCAAGAC 
TGTCGGAATC TTGATTTTTT GGATTTGGGT TACAATCGTC TTCGAAGCTT GTCCCGAAAT 
GCATTTGCTG GCCTCTTGAA GTTAAAGGAG CTCCACCTGG AGCACAACCA GTTTTCCAAG 
ATCAACTTTG CTCATTTTCC ACGTCTCTTC AACCTCCGCT CAATTTACTT ACAATGGAAC 
AGGATTCGCT CCATTAGCCA AGGTTTGACA TGGACTTGGA GTTCCTTACA CAACTTGGAT 
TTATCAGGGA ATGACATCCA AGGAATTGAG CCGGGCACAT TTAAATGCCT CCCCAATTTA 
CAAAAATTGA ATTTGGATTC CAACAAGCTC ACCAATATCT CACAGGAAAC TGTCAATGCG 
TGGATATCAT TAATATCCAT CACATTGTCT GGAAATATGT GGGAATGCAG TCGGAGCATT 
TGTCCTTTAT TTTATTGGCT TAAGAATTTC AAAGGAAATA AGGAAAGCAC CATGATATGT 
GCGGGACCTA AGCACATCCA GGGTGAAAAG GTTAGTGATG CAGTGGAAAC ATATAATATC 
TGTTCTGAAG TCCAGGTGGT CAACACAGAA AGATCACACC TGGTGCCCCA AACTCCCCAG 
AAACCTCTGA TTATCCCTAG ACCTACCATC TTCAAACCTG ACGTCACCCA ATCCACCTTT 
GAAACACCAA GCCCTTCCCC AGGGTTTCAG ATTCCTGGCG CAGAGCAAGA GTATGAGCAT 
GTTTCATTTC ACAAAATTAT TGCCGGGAGT GTGGCTCTCT TTCTCTCAGT GGCCATGATC 
CTCTTGGTGA TCTATGTGTC TTGGAAACGC TACCCAGCCA GCATGAAACA ACTCCAGCAA 
CACTCTCTTA TGAAGAGGCG GCGGAAAAAG GCCAGAGAGT CTGAAAGACA AATGAATTCC 
CCTTTACAGG AGTATTATGT GGACTACAAG CCTACAAACT CTGAGACCAT GGATATATCG 
GTTAATGGAT CTGGGCCCTG CACATATACC ATCTCTGGCT CCAGGGAATG TGAGGTATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001269857.1
CDS	319..1878
Translation	MPGFHLITQLKGMSVVLVLLPTLLLVMLTGAQRACPKNCRCDGKIVYCESHAFADIPENISGGSQGLSLRFNSIQKLKSNQFAGLNQLIWLYLDHNYISSVDEDAFQGIRRLKELILSSNKITYLHNKTFHPVPNLRNLDLSYNKLQTLQSEQFKGLRKLIILHLRSNSLKTVPIRVFQDCRNLDFLDLGYNRLRSLSRNAFAGLLKLKELHLEHNQFSKINFAHFPRLFNLRSIYLQWNRIRSISQGLTWTWSSLHNLDLSGNDIQGIEPGTFKCLPNLQKLNLDSNKLTNISQETVNAWISLISITLSGNMWECSRSICPLFYWLKNFKGNKESTMICAGPKHIQGEKVSDAVETYNICSEVQVVNTERSHLVPQTPQKPLIIPRPTIFKPDVTQSTFETPSPSPGFQIPGAEQEYEHVSFHKIIAGSVALFLSVAMILLVIYVSWKRYPASMKQLQQHSLMKRRRKKARESERQMNSPLQEYYVDYKPTNSETMDISVNGSGPCTYTISGSRECEV

Target ORF information:

RefSeq Version	NM_001282928.2
Organism	Homo sapiens(human)
Definition	Homo sapiens leucine rich repeat transmembrane neuronal 4 (LRRTM4), transcript variant 4, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001282928.2

ORF Insert Sequence:

ATGCCAGGTT TCCATTTAAT TACGCAGCTG AAAGGCATGA GTGTGGTGCT GGTGCTACTT 
CCTACACTGC TGCTTGTTAT GCTCACGGGT GCTCAGAGAG CTTGCCCAAA GAACTGCAGA 
TGTGATGGCA AAATTGTGTA CTGTGAGTCT CATGCTTTCG CAGATATCCC TGAGAACATT 
TCTGGAGGGT CACAAGGCTT ATCATTAAGG TTCAACAGCA TTCAGAAGCT CAAATCCAAT 
CAGTTTGCCG GCCTTAACCA GCTTATATGG CTTTATCTTG ACCATAATTA CATTAGCTCA 
GTGGATGAAG ATGCATTTCA AGGGATCCGT AGACTGAAAG AATTAATTCT AAGCTCCAAC 
AAAATTACTT ATCTGCACAA TAAAACATTT CACCCAGTTC CCAATCTCCG CAATCTGGAC 
CTCTCCTACA ATAAGCTTCA GACATTGCAA TCTGAACAAT TTAAAGGCCT TCGGAAACTC 
ATCATTTTGC ACTTGAGATC TAACTCACTA AAGACTGTGC CCATAAGAGT TTTTCAAGAC 
TGTCGGAATC TTGATTTTTT GGATTTGGGT TACAATCGTC TTCGAAGCTT GTCCCGAAAT 
GCATTTGCTG GCCTCTTGAA GTTAAAGGAG CTCCACCTGG AGCACAACCA GTTTTCCAAG 
ATCAACTTTG CTCATTTTCC ACGTCTCTTC AACCTCCGCT CAATTTACTT ACAATGGAAC 
AGGATTCGCT CCATTAGCCA AGGTTTGACA TGGACTTGGA GTTCCTTACA CAACTTGGAT 
TTATCAGGGA ATGACATCCA AGGAATTGAG CCGGGCACAT TTAAATGCCT CCCCAATTTA 
CAAAAATTGA ATTTGGATTC CAACAAGCTC ACCAATATCT CACAGGAAAC TGTCAATGCG 
TGGATATCAT TAATATCCAT CACATTGTCT GGAAATATGT GGGAATGCAG TCGGAGCATT 
TGTCCTTTAT TTTATTGGCT TAAGAATTTC AAAGGAAATA AGGAAAGCAC CATGATATGT 
GCGGGACCTA AGCACATCCA GGGTGAAAAG GTTAGTGATG CAGTGGAAAC ATATAATATC 
TGTTCTGAAG TCCAGGTGGT CAACACAGAA AGATCACACC TGGTGCCCCA AACTCCCCAG 
AAACCTCTGA TTATCCCTAG ACCTACCATC TTCAAACCTG ACGTCACCCA ATCCACCTTT 
GAAACACCAA GCCCTTCCCC AGGGTTTCAG ATTCCTGGCG CAGAGCAAGA GTATGAGCAT 
GTTTCATTTC ACAAAATTAT TGCCGGGAGT GTGGCTCTCT TTCTCTCAGT GGCCATGATC 
CTCTTGGTGA TCTATGTGTC TTGGAAACGC TACCCAGCCA GCATGAAACA ACTCCAGCAA 
CACTCTCTTA TGAAGAGGCG GCGGAAAAAG GCCAGAGAGT CTGAAAGACA AATGAATTCC 
CCTTTACAGG AGTATTATGT GGACTACAAG CCTACAAACT CTGAGACCAT GGATATATCG 
GTTAATGGAT CTGGGCCCTG CACATATACC ATCTCTGGCT CCAGGGAATG TGAGGTATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

LRRTM4 ( NM_001282928.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_001269857.1 Homo sapiens leucine rich repeat transmembrane neuronal 4 (LRRTM4), transcript variant 4, mRNA.

Price & Availability↑

CloneID	OHu07998
Clone ID Related Accession (Same CDS sequence)	NM_001282928.2 , NM_001282928.3
Accession Version	NM_001282928.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1560bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-09-29
Organism	Homo sapiens(human)
Product	leucine-rich repeat transmembrane neuronal protein 4 isoform c precursor
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AC079614.7, AK122612.1 and BC098301.1. On Jun 2, 2019 this sequence version replaced NM_001282928.2. Transcript Variant: This variant (4) lacks an exon in the 5' region and its transcription extends past a splice site that is used in variant 1, resulting in a novel 3' coding region and 3' UTR. It initiates translation at an alternate start codon compared to variant 1 and encodes isoform c, which distinct N- and C-termini and is shorter than isoform a. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. ##Evidence-Data-START## Transcript exon combination :: SRR1803615.178693.1, SRR1660807.138752.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2154665, SAMEA2157437 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGCCAGGTT TCCATTTAAT TACGCAGCTG AAAGGCATGA GTGTGGTGCT GGTGCTACTT 
CCTACACTGC TGCTTGTTAT GCTCACGGGT GCTCAGAGAG CTTGCCCAAA GAACTGCAGA 
TGTGATGGCA AAATTGTGTA CTGTGAGTCT CATGCTTTCG CAGATATCCC TGAGAACATT 
TCTGGAGGGT CACAAGGCTT ATCATTAAGG TTCAACAGCA TTCAGAAGCT CAAATCCAAT 
CAGTTTGCCG GCCTTAACCA GCTTATATGG CTTTATCTTG ACCATAATTA CATTAGCTCA 
GTGGATGAAG ATGCATTTCA AGGGATCCGT AGACTGAAAG AATTAATTCT AAGCTCCAAC 
AAAATTACTT ATCTGCACAA TAAAACATTT CACCCAGTTC CCAATCTCCG CAATCTGGAC 
CTCTCCTACA ATAAGCTTCA GACATTGCAA TCTGAACAAT TTAAAGGCCT TCGGAAACTC 
ATCATTTTGC ACTTGAGATC TAACTCACTA AAGACTGTGC CCATAAGAGT TTTTCAAGAC 
TGTCGGAATC TTGATTTTTT GGATTTGGGT TACAATCGTC TTCGAAGCTT GTCCCGAAAT 
GCATTTGCTG GCCTCTTGAA GTTAAAGGAG CTCCACCTGG AGCACAACCA GTTTTCCAAG 
ATCAACTTTG CTCATTTTCC ACGTCTCTTC AACCTCCGCT CAATTTACTT ACAATGGAAC 
AGGATTCGCT CCATTAGCCA AGGTTTGACA TGGACTTGGA GTTCCTTACA CAACTTGGAT 
TTATCAGGGA ATGACATCCA AGGAATTGAG CCGGGCACAT TTAAATGCCT CCCCAATTTA 
CAAAAATTGA ATTTGGATTC CAACAAGCTC ACCAATATCT CACAGGAAAC TGTCAATGCG 
TGGATATCAT TAATATCCAT CACATTGTCT GGAAATATGT GGGAATGCAG TCGGAGCATT 
TGTCCTTTAT TTTATTGGCT TAAGAATTTC AAAGGAAATA AGGAAAGCAC CATGATATGT 
GCGGGACCTA AGCACATCCA GGGTGAAAAG GTTAGTGATG CAGTGGAAAC ATATAATATC 
TGTTCTGAAG TCCAGGTGGT CAACACAGAA AGATCACACC TGGTGCCCCA AACTCCCCAG 
AAACCTCTGA TTATCCCTAG ACCTACCATC TTCAAACCTG ACGTCACCCA ATCCACCTTT 
GAAACACCAA GCCCTTCCCC AGGGTTTCAG ATTCCTGGCG CAGAGCAAGA GTATGAGCAT 
GTTTCATTTC ACAAAATTAT TGCCGGGAGT GTGGCTCTCT TTCTCTCAGT GGCCATGATC 
CTCTTGGTGA TCTATGTGTC TTGGAAACGC TACCCAGCCA GCATGAAACA ACTCCAGCAA 
CACTCTCTTA TGAAGAGGCG GCGGAAAAAG GCCAGAGAGT CTGAAAGACA AATGAATTCC 
CCTTTACAGG AGTATTATGT GGACTACAAG CCTACAAACT CTGAGACCAT GGATATATCG 
GTTAATGGAT CTGGGCCCTG CACATATACC ATCTCTGGCT CCAGGGAATG TGAGGTATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001269857.1
CDS	262..1821
Translation	MPGFHLITQLKGMSVVLVLLPTLLLVMLTGAQRACPKNCRCDGKIVYCESHAFADIPENISGGSQGLSLRFNSIQKLKSNQFAGLNQLIWLYLDHNYISSVDEDAFQGIRRLKELILSSNKITYLHNKTFHPVPNLRNLDLSYNKLQTLQSEQFKGLRKLIILHLRSNSLKTVPIRVFQDCRNLDFLDLGYNRLRSLSRNAFAGLLKLKELHLEHNQFSKINFAHFPRLFNLRSIYLQWNRIRSISQGLTWTWSSLHNLDLSGNDIQGIEPGTFKCLPNLQKLNLDSNKLTNISQETVNAWISLISITLSGNMWECSRSICPLFYWLKNFKGNKESTMICAGPKHIQGEKVSDAVETYNICSEVQVVNTERSHLVPQTPQKPLIIPRPTIFKPDVTQSTFETPSPSPGFQIPGAEQEYEHVSFHKIIAGSVALFLSVAMILLVIYVSWKRYPASMKQLQQHSLMKRRRKKARESERQMNSPLQEYYVDYKPTNSETMDISVNGSGPCTYTISGSRECEV

Target ORF information:

RefSeq Version	NM_001282928.3
Organism	Homo sapiens(human)
Definition	Homo sapiens leucine rich repeat transmembrane neuronal 4 (LRRTM4), transcript variant 4, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001282928.3

ORF Insert Sequence:

ATGCCAGGTT TCCATTTAAT TACGCAGCTG AAAGGCATGA GTGTGGTGCT GGTGCTACTT 
CCTACACTGC TGCTTGTTAT GCTCACGGGT GCTCAGAGAG CTTGCCCAAA GAACTGCAGA 
TGTGATGGCA AAATTGTGTA CTGTGAGTCT CATGCTTTCG CAGATATCCC TGAGAACATT 
TCTGGAGGGT CACAAGGCTT ATCATTAAGG TTCAACAGCA TTCAGAAGCT CAAATCCAAT 
CAGTTTGCCG GCCTTAACCA GCTTATATGG CTTTATCTTG ACCATAATTA CATTAGCTCA 
GTGGATGAAG ATGCATTTCA AGGGATCCGT AGACTGAAAG AATTAATTCT AAGCTCCAAC 
AAAATTACTT ATCTGCACAA TAAAACATTT CACCCAGTTC CCAATCTCCG CAATCTGGAC 
CTCTCCTACA ATAAGCTTCA GACATTGCAA TCTGAACAAT TTAAAGGCCT TCGGAAACTC 
ATCATTTTGC ACTTGAGATC TAACTCACTA AAGACTGTGC CCATAAGAGT TTTTCAAGAC 
TGTCGGAATC TTGATTTTTT GGATTTGGGT TACAATCGTC TTCGAAGCTT GTCCCGAAAT 
GCATTTGCTG GCCTCTTGAA GTTAAAGGAG CTCCACCTGG AGCACAACCA GTTTTCCAAG 
ATCAACTTTG CTCATTTTCC ACGTCTCTTC AACCTCCGCT CAATTTACTT ACAATGGAAC 
AGGATTCGCT CCATTAGCCA AGGTTTGACA TGGACTTGGA GTTCCTTACA CAACTTGGAT 
TTATCAGGGA ATGACATCCA AGGAATTGAG CCGGGCACAT TTAAATGCCT CCCCAATTTA 
CAAAAATTGA ATTTGGATTC CAACAAGCTC ACCAATATCT CACAGGAAAC TGTCAATGCG 
TGGATATCAT TAATATCCAT CACATTGTCT GGAAATATGT GGGAATGCAG TCGGAGCATT 
TGTCCTTTAT TTTATTGGCT TAAGAATTTC AAAGGAAATA AGGAAAGCAC CATGATATGT 
GCGGGACCTA AGCACATCCA GGGTGAAAAG GTTAGTGATG CAGTGGAAAC ATATAATATC 
TGTTCTGAAG TCCAGGTGGT CAACACAGAA AGATCACACC TGGTGCCCCA AACTCCCCAG 
AAACCTCTGA TTATCCCTAG ACCTACCATC TTCAAACCTG ACGTCACCCA ATCCACCTTT 
GAAACACCAA GCCCTTCCCC AGGGTTTCAG ATTCCTGGCG CAGAGCAAGA GTATGAGCAT 
GTTTCATTTC ACAAAATTAT TGCCGGGAGT GTGGCTCTCT TTCTCTCAGT GGCCATGATC 
CTCTTGGTGA TCTATGTGTC TTGGAAACGC TACCCAGCCA GCATGAAACA ACTCCAGCAA 
CACTCTCTTA TGAAGAGGCG GCGGAAAAAG GCCAGAGAGT CTGAAAGACA AATGAATTCC 
CCTTTACAGG AGTATTATGT GGACTACAAG CCTACAAACT CTGAGACCAT GGATATATCG 
GTTAATGGAT CTGGGCCCTG CACATATACC ATCTCTGGCT CCAGGGAATG TGAGGTATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

LRRTM4 ( NM_001282924.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_001269853.1 Homo sapiens leucine rich repeat transmembrane neuronal 4 (LRRTM4), transcript variant 3, mRNA.

Price & Availability↑

CloneID	OHu07189
Clone ID Related Accession (Same CDS sequence)	NM_001282924.2 , NM_001134745.2
Accession Version	NM_001282924.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1773bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-09-24
Organism	Homo sapiens(human)
Product	leucine-rich repeat transmembrane neuronal protein 4 isoform a precursor
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AC079614.7, AK122612.1, AY358324.1, AC068616.5 and AI079273.1. On Aug 29, 2016 this sequence version replaced NM_001282924.1. Transcript Variant: This variant (3) has an alternate splice site in the 5' UTR, compared to variant 1. Variants 1 and 3 encode the same isoform a. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. ##Evidence-Data-START## Transcript exon combination :: AK122612.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2145743, SAMN03465404 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGGTTTCC ATTTAATTAC GCAGCTGAAA GGCATGAGTG TGGTGCTGGT GCTACTTCCT 
ACACTGCTGC TTGTTATGCT CACGGGTGCT CAGAGAGCTT GCCCAAAGAA CTGCAGATGT 
GATGGCAAAA TTGTGTACTG TGAGTCTCAT GCTTTCGCAG ATATCCCTGA GAACATTTCT 
GGAGGGTCAC AAGGCTTATC ATTAAGGTTC AACAGCATTC AGAAGCTCAA ATCCAATCAG 
TTTGCCGGCC TTAACCAGCT TATATGGCTT TATCTTGACC ATAATTACAT TAGCTCAGTG 
GATGAAGATG CATTTCAAGG GATCCGTAGA CTGAAAGAAT TAATTCTAAG CTCCAACAAA 
ATTACTTATC TGCACAATAA AACATTTCAC CCAGTTCCCA ATCTCCGCAA TCTGGACCTC 
TCCTACAATA AGCTTCAGAC ATTGCAATCT GAACAATTTA AAGGCCTTCG GAAACTCATC 
ATTTTGCACT TGAGATCTAA CTCACTAAAG ACTGTGCCCA TAAGAGTTTT TCAAGACTGT 
CGGAATCTTG ATTTTTTGGA TTTGGGTTAC AATCGTCTTC GAAGCTTGTC CCGAAATGCA 
TTTGCTGGCC TCTTGAAGTT AAAGGAGCTC CACCTGGAGC ACAACCAGTT TTCCAAGATC 
AACTTTGCTC ATTTTCCACG TCTCTTCAAC CTCCGCTCAA TTTACTTACA ATGGAACAGG 
ATTCGCTCCA TTAGCCAAGG TTTGACATGG ACTTGGAGTT CCTTACACAA CTTGGATTTA 
TCAGGGAATG ACATCCAAGG AATTGAGCCG GGCACATTTA AATGCCTCCC CAATTTACAA 
AAATTGAATT TGGATTCCAA CAAGCTCACC AATATCTCAC AGGAAACTGT CAATGCGTGG 
ATATCATTAA TATCCATCAC ATTGTCTGGA AATATGTGGG AATGCAGTCG GAGCATTTGT 
CCTTTATTTT ATTGGCTTAA GAATTTCAAA GGAAATAAGG AAAGCACCAT GATATGTGCG 
GGACCTAAGC ACATCCAGGG TGAAAAGGTT AGTGATGCAG TGGAAACATA TAATATCTGT 
TCTGAAGTCC AGGTGGTCAA CACAGAAAGA TCACACCTGG TGCCCCAAAC TCCCCAGAAA 
CCTCTGATTA TCCCTAGACC TACCATCTTC AAACCTGACG TCACCCAATC CACCTTTGAA 
ACACCAAGCC CTTCCCCAGG GTTTCAGATT CCTGGCGCAG AGCAAGAGTA TGAGCATGTT 
TCATTTCACA AAATTATTGC CGGGAGTGTG GCTCTCTTTC TCTCAGTGGC CATGATCCTC 
TTGGTGATCT ATGTGTCTTG GAAACGCTAC CCAGCCAGCA TGAAACAACT CCAGCAACAC 
TCTCTTATGA AGAGGCGGCG GAAAAAGGCC AGAGAGTCTG AAAGACAAAT GAATTCCCCT 
TTACAGGAGT ATTATGTGGA CTACAAGCCT ACAAACTCTG AGACCATGGA TATATCGGTT 
AATGGATCTG GGCCCTGCAC ATATACCATC TCTGGCTCCA GGGAATGTGA GATGCCACAC 
CACATGAAGC CCTTGCCATA TTACAGCTAT GACCAGCCTG TGATCGGGTA CTGCCAGGCC 
CACCAGCCAC TCCATGTCAC CAAGGGCTAT GAGACAGTGT CTCCAGAGCA GGACGAAAGC 
CCCGGCCTGG AGCTGGGCCG AGACCACAGC TTCATCGCCA CCATCGCCAG GTCGGCAGCA 
CCGGCCATCT ACCTAGAGAG AATTGCAAAC TAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001269853.1
CDS	403..2175
Translation	MGFHLITQLKGMSVVLVLLPTLLLVMLTGAQRACPKNCRCDGKIVYCESHAFADIPENISGGSQGLSLRFNSIQKLKSNQFAGLNQLIWLYLDHNYISSVDEDAFQGIRRLKELILSSNKITYLHNKTFHPVPNLRNLDLSYNKLQTLQSEQFKGLRKLIILHLRSNSLKTVPIRVFQDCRNLDFLDLGYNRLRSLSRNAFAGLLKLKELHLEHNQFSKINFAHFPRLFNLRSIYLQWNRIRSISQGLTWTWSSLHNLDLSGNDIQGIEPGTFKCLPNLQKLNLDSNKLTNISQETVNAWISLISITLSGNMWECSRSICPLFYWLKNFKGNKESTMICAGPKHIQGEKVSDAVETYNICSEVQVVNTERSHLVPQTPQKPLIIPRPTIFKPDVTQSTFETPSPSPGFQIPGAEQEYEHVSFHKIIAGSVALFLSVAMILLVIYVSWKRYPASMKQLQQHSLMKRRRKKARESERQMNSPLQEYYVDYKPTNSETMDISVNGSGPCTYTISGSRECEMPHHMKPLPYYSYDQPVIGYCQAHQPLHVTKGYETVSPEQDESPGLELGRDHSFIATIARSAAPAIYLERIAN

Target ORF information:

RefSeq Version	NM_001282924.2
Organism	Homo sapiens(human)
Definition	Homo sapiens leucine rich repeat transmembrane neuronal 4 (LRRTM4), transcript variant 3, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001282924.2

ORF Insert Sequence:

ATGGGTTTCC ATTTAATTAC GCAGCTGAAA GGCATGAGTG TGGTGCTGGT GCTACTTCCT 
ACACTGCTGC TTGTTATGCT CACGGGTGCT CAGAGAGCTT GCCCAAAGAA CTGCAGATGT 
GATGGCAAAA TTGTGTACTG TGAGTCTCAT GCTTTCGCAG ATATCCCTGA GAACATTTCT 
GGAGGGTCAC AAGGCTTATC ATTAAGGTTC AACAGCATTC AGAAGCTCAA ATCCAATCAG 
TTTGCCGGCC TTAACCAGCT TATATGGCTT TATCTTGACC ATAATTACAT TAGCTCAGTG 
GATGAAGATG CATTTCAAGG GATCCGTAGA CTGAAAGAAT TAATTCTAAG CTCCAACAAA 
ATTACTTATC TGCACAATAA AACATTTCAC CCAGTTCCCA ATCTCCGCAA TCTGGACCTC 
TCCTACAATA AGCTTCAGAC ATTGCAATCT GAACAATTTA AAGGCCTTCG GAAACTCATC 
ATTTTGCACT TGAGATCTAA CTCACTAAAG ACTGTGCCCA TAAGAGTTTT TCAAGACTGT 
CGGAATCTTG ATTTTTTGGA TTTGGGTTAC AATCGTCTTC GAAGCTTGTC CCGAAATGCA 
TTTGCTGGCC TCTTGAAGTT AAAGGAGCTC CACCTGGAGC ACAACCAGTT TTCCAAGATC 
AACTTTGCTC ATTTTCCACG TCTCTTCAAC CTCCGCTCAA TTTACTTACA ATGGAACAGG 
ATTCGCTCCA TTAGCCAAGG TTTGACATGG ACTTGGAGTT CCTTACACAA CTTGGATTTA 
TCAGGGAATG ACATCCAAGG AATTGAGCCG GGCACATTTA AATGCCTCCC CAATTTACAA 
AAATTGAATT TGGATTCCAA CAAGCTCACC AATATCTCAC AGGAAACTGT CAATGCGTGG 
ATATCATTAA TATCCATCAC ATTGTCTGGA AATATGTGGG AATGCAGTCG GAGCATTTGT 
CCTTTATTTT ATTGGCTTAA GAATTTCAAA GGAAATAAGG AAAGCACCAT GATATGTGCG 
GGACCTAAGC ACATCCAGGG TGAAAAGGTT AGTGATGCAG TGGAAACATA TAATATCTGT 
TCTGAAGTCC AGGTGGTCAA CACAGAAAGA TCACACCTGG TGCCCCAAAC TCCCCAGAAA 
CCTCTGATTA TCCCTAGACC TACCATCTTC AAACCTGACG TCACCCAATC CACCTTTGAA 
ACACCAAGCC CTTCCCCAGG GTTTCAGATT CCTGGCGCAG AGCAAGAGTA TGAGCATGTT 
TCATTTCACA AAATTATTGC CGGGAGTGTG GCTCTCTTTC TCTCAGTGGC CATGATCCTC 
TTGGTGATCT ATGTGTCTTG GAAACGCTAC CCAGCCAGCA TGAAACAACT CCAGCAACAC 
TCTCTTATGA AGAGGCGGCG GAAAAAGGCC AGAGAGTCTG AAAGACAAAT GAATTCCCCT 
TTACAGGAGT ATTATGTGGA CTACAAGCCT ACAAACTCTG AGACCATGGA TATATCGGTT 
AATGGATCTG GGCCCTGCAC ATATACCATC TCTGGCTCCA GGGAATGTGA GATGCCACAC 
CACATGAAGC CCTTGCCATA TTACAGCTAT GACCAGCCTG TGATCGGGTA CTGCCAGGCC 
CACCAGCCAC TCCATGTCAC CAAGGGCTAT GAGACAGTGT CTCCAGAGCA GGACGAAAGC 
CCCGGCCTGG AGCTGGGCCG AGACCACAGC TTCATCGCCA CCATCGCCAG GTCGGCAGCA 
CCGGCCATCT ACCTAGAGAG AATTGCAAAC TAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

LRRTM4 ( NM_001134745.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_001128217.1 Homo sapiens leucine rich repeat transmembrane neuronal 4 (LRRTM4), transcript variant 1, mRNA.

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CloneID	OHu07189
Clone ID Related Accession (Same CDS sequence)	NM_001282924.2 , NM_001134745.2
Accession Version	NM_001134745.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1773bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-09-11
Organism	Homo sapiens(human)
Product	leucine-rich repeat transmembrane neuronal protein 4 isoform a precursor
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AC079614.7, AK126961.1, AY358324.1, AC068616.5 and AI079273.1. This sequence is a reference standard in the RefSeqGene project. On Aug 29, 2016 this sequence version replaced NM_001134745.1. Transcript Variant: This variant (1) and variant 3 encode the same isoform (a). Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. ##Evidence-Data-START## Transcript exon combination :: SRR1803613.48027.1, SRR1803611.114833.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2145743, SAMEA2154665 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## RefSeq Select criteria :: based on conservation ##RefSeq-Attributes-END## COMPLETENESS: complete on the 3' end.

ATGGGTTTCC ATTTAATTAC GCAGCTGAAA GGCATGAGTG TGGTGCTGGT GCTACTTCCT 
ACACTGCTGC TTGTTATGCT CACGGGTGCT CAGAGAGCTT GCCCAAAGAA CTGCAGATGT 
GATGGCAAAA TTGTGTACTG TGAGTCTCAT GCTTTCGCAG ATATCCCTGA GAACATTTCT 
GGAGGGTCAC AAGGCTTATC ATTAAGGTTC AACAGCATTC AGAAGCTCAA ATCCAATCAG 
TTTGCCGGCC TTAACCAGCT TATATGGCTT TATCTTGACC ATAATTACAT TAGCTCAGTG 
GATGAAGATG CATTTCAAGG GATCCGTAGA CTGAAAGAAT TAATTCTAAG CTCCAACAAA 
ATTACTTATC TGCACAATAA AACATTTCAC CCAGTTCCCA ATCTCCGCAA TCTGGACCTC 
TCCTACAATA AGCTTCAGAC ATTGCAATCT GAACAATTTA AAGGCCTTCG GAAACTCATC 
ATTTTGCACT TGAGATCTAA CTCACTAAAG ACTGTGCCCA TAAGAGTTTT TCAAGACTGT 
CGGAATCTTG ATTTTTTGGA TTTGGGTTAC AATCGTCTTC GAAGCTTGTC CCGAAATGCA 
TTTGCTGGCC TCTTGAAGTT AAAGGAGCTC CACCTGGAGC ACAACCAGTT TTCCAAGATC 
AACTTTGCTC ATTTTCCACG TCTCTTCAAC CTCCGCTCAA TTTACTTACA ATGGAACAGG 
ATTCGCTCCA TTAGCCAAGG TTTGACATGG ACTTGGAGTT CCTTACACAA CTTGGATTTA 
TCAGGGAATG ACATCCAAGG AATTGAGCCG GGCACATTTA AATGCCTCCC CAATTTACAA 
AAATTGAATT TGGATTCCAA CAAGCTCACC AATATCTCAC AGGAAACTGT CAATGCGTGG 
ATATCATTAA TATCCATCAC ATTGTCTGGA AATATGTGGG AATGCAGTCG GAGCATTTGT 
CCTTTATTTT ATTGGCTTAA GAATTTCAAA GGAAATAAGG AAAGCACCAT GATATGTGCG 
GGACCTAAGC ACATCCAGGG TGAAAAGGTT AGTGATGCAG TGGAAACATA TAATATCTGT 
TCTGAAGTCC AGGTGGTCAA CACAGAAAGA TCACACCTGG TGCCCCAAAC TCCCCAGAAA 
CCTCTGATTA TCCCTAGACC TACCATCTTC AAACCTGACG TCACCCAATC CACCTTTGAA 
ACACCAAGCC CTTCCCCAGG GTTTCAGATT CCTGGCGCAG AGCAAGAGTA TGAGCATGTT 
TCATTTCACA AAATTATTGC CGGGAGTGTG GCTCTCTTTC TCTCAGTGGC CATGATCCTC 
TTGGTGATCT ATGTGTCTTG GAAACGCTAC CCAGCCAGCA TGAAACAACT CCAGCAACAC 
TCTCTTATGA AGAGGCGGCG GAAAAAGGCC AGAGAGTCTG AAAGACAAAT GAATTCCCCT 
TTACAGGAGT ATTATGTGGA CTACAAGCCT ACAAACTCTG AGACCATGGA TATATCGGTT 
AATGGATCTG GGCCCTGCAC ATATACCATC TCTGGCTCCA GGGAATGTGA GATGCCACAC 
CACATGAAGC CCTTGCCATA TTACAGCTAT GACCAGCCTG TGATCGGGTA CTGCCAGGCC 
CACCAGCCAC TCCATGTCAC CAAGGGCTAT GAGACAGTGT CTCCAGAGCA GGACGAAAGC 
CCCGGCCTGG AGCTGGGCCG AGACCACAGC TTCATCGCCA CCATCGCCAG GTCGGCAGCA 
CCGGCCATCT ACCTAGAGAG AATTGCAAAC TAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001128217.1
CDS	473..2245
Translation	MGFHLITQLKGMSVVLVLLPTLLLVMLTGAQRACPKNCRCDGKIVYCESHAFADIPENISGGSQGLSLRFNSIQKLKSNQFAGLNQLIWLYLDHNYISSVDEDAFQGIRRLKELILSSNKITYLHNKTFHPVPNLRNLDLSYNKLQTLQSEQFKGLRKLIILHLRSNSLKTVPIRVFQDCRNLDFLDLGYNRLRSLSRNAFAGLLKLKELHLEHNQFSKINFAHFPRLFNLRSIYLQWNRIRSISQGLTWTWSSLHNLDLSGNDIQGIEPGTFKCLPNLQKLNLDSNKLTNISQETVNAWISLISITLSGNMWECSRSICPLFYWLKNFKGNKESTMICAGPKHIQGEKVSDAVETYNICSEVQVVNTERSHLVPQTPQKPLIIPRPTIFKPDVTQSTFETPSPSPGFQIPGAEQEYEHVSFHKIIAGSVALFLSVAMILLVIYVSWKRYPASMKQLQQHSLMKRRRKKARESERQMNSPLQEYYVDYKPTNSETMDISVNGSGPCTYTISGSRECEMPHHMKPLPYYSYDQPVIGYCQAHQPLHVTKGYETVSPEQDESPGLELGRDHSFIATIARSAAPAIYLERIAN

Target ORF information:

RefSeq Version	NM_001134745.2
Organism	Homo sapiens(human)
Definition	Homo sapiens leucine rich repeat transmembrane neuronal 4 (LRRTM4), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001134745.2

ORF Insert Sequence:

ATGGGTTTCC ATTTAATTAC GCAGCTGAAA GGCATGAGTG TGGTGCTGGT GCTACTTCCT 
ACACTGCTGC TTGTTATGCT CACGGGTGCT CAGAGAGCTT GCCCAAAGAA CTGCAGATGT 
GATGGCAAAA TTGTGTACTG TGAGTCTCAT GCTTTCGCAG ATATCCCTGA GAACATTTCT 
GGAGGGTCAC AAGGCTTATC ATTAAGGTTC AACAGCATTC AGAAGCTCAA ATCCAATCAG 
TTTGCCGGCC TTAACCAGCT TATATGGCTT TATCTTGACC ATAATTACAT TAGCTCAGTG 
GATGAAGATG CATTTCAAGG GATCCGTAGA CTGAAAGAAT TAATTCTAAG CTCCAACAAA 
ATTACTTATC TGCACAATAA AACATTTCAC CCAGTTCCCA ATCTCCGCAA TCTGGACCTC 
TCCTACAATA AGCTTCAGAC ATTGCAATCT GAACAATTTA AAGGCCTTCG GAAACTCATC 
ATTTTGCACT TGAGATCTAA CTCACTAAAG ACTGTGCCCA TAAGAGTTTT TCAAGACTGT 
CGGAATCTTG ATTTTTTGGA TTTGGGTTAC AATCGTCTTC GAAGCTTGTC CCGAAATGCA 
TTTGCTGGCC TCTTGAAGTT AAAGGAGCTC CACCTGGAGC ACAACCAGTT TTCCAAGATC 
AACTTTGCTC ATTTTCCACG TCTCTTCAAC CTCCGCTCAA TTTACTTACA ATGGAACAGG 
ATTCGCTCCA TTAGCCAAGG TTTGACATGG ACTTGGAGTT CCTTACACAA CTTGGATTTA 
TCAGGGAATG ACATCCAAGG AATTGAGCCG GGCACATTTA AATGCCTCCC CAATTTACAA 
AAATTGAATT TGGATTCCAA CAAGCTCACC AATATCTCAC AGGAAACTGT CAATGCGTGG 
ATATCATTAA TATCCATCAC ATTGTCTGGA AATATGTGGG AATGCAGTCG GAGCATTTGT 
CCTTTATTTT ATTGGCTTAA GAATTTCAAA GGAAATAAGG AAAGCACCAT GATATGTGCG 
GGACCTAAGC ACATCCAGGG TGAAAAGGTT AGTGATGCAG TGGAAACATA TAATATCTGT 
TCTGAAGTCC AGGTGGTCAA CACAGAAAGA TCACACCTGG TGCCCCAAAC TCCCCAGAAA 
CCTCTGATTA TCCCTAGACC TACCATCTTC AAACCTGACG TCACCCAATC CACCTTTGAA 
ACACCAAGCC CTTCCCCAGG GTTTCAGATT CCTGGCGCAG AGCAAGAGTA TGAGCATGTT 
TCATTTCACA AAATTATTGC CGGGAGTGTG GCTCTCTTTC TCTCAGTGGC CATGATCCTC 
TTGGTGATCT ATGTGTCTTG GAAACGCTAC CCAGCCAGCA TGAAACAACT CCAGCAACAC 
TCTCTTATGA AGAGGCGGCG GAAAAAGGCC AGAGAGTCTG AAAGACAAAT GAATTCCCCT 
TTACAGGAGT ATTATGTGGA CTACAAGCCT ACAAACTCTG AGACCATGGA TATATCGGTT 
AATGGATCTG GGCCCTGCAC ATATACCATC TCTGGCTCCA GGGAATGTGA GATGCCACAC 
CACATGAAGC CCTTGCCATA TTACAGCTAT GACCAGCCTG TGATCGGGTA CTGCCAGGCC 
CACCAGCCAC TCCATGTCAC CAAGGGCTAT GAGACAGTGT CTCCAGAGCA GGACGAAAGC 
CCCGGCCTGG AGCTGGGCCG AGACCACAGC TTCATCGCCA CCATCGCCAG GTCGGCAGCA 
CCGGCCATCT ACCTAGAGAG AATTGCAAAC TAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

LRRTM4 ( NM_001330370.1 ) cDNA ORF clone, Homo sapiens(human) -> NP_001317299.1 Homo sapiens leucine rich repeat transmembrane neuronal 4 (LRRTM4), transcript variant 5, mRNA.

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CloneID	OHu72524
Clone ID Related Accession (Same CDS sequence)	NM_001330370.1
Accession Version	NM_001330370.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1776bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-09-23
Organism	Homo sapiens(human)
Product	leucine-rich repeat transmembrane neuronal protein 4 isoform d precursor
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AC079614.7 and AC068616.5. On Aug 29, 2016 this sequence version replaced XM_011533117.2. Transcript Variant: This variant (5) lacks an exon in the 5' region and initiates translation at an alternate start codon compared to variant 1. The encoded isoform (d) has a distinct N-terminus and is longer than isoform a. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. ##Evidence-Data-START## Transcript exon combination :: SRR1660807.21823.1, SRR1803615.122071.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2154665, SAMEA2157437 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGCCAGGTT TCCATTTAAT TACGCAGCTG AAAGGCATGA GTGTGGTGCT GGTGCTACTT 
CCTACACTGC TGCTTGTTAT GCTCACGGGT GCTCAGAGAG CTTGCCCAAA GAACTGCAGA 
TGTGATGGCA AAATTGTGTA CTGTGAGTCT CATGCTTTCG CAGATATCCC TGAGAACATT 
TCTGGAGGGT CACAAGGCTT ATCATTAAGG TTCAACAGCA TTCAGAAGCT CAAATCCAAT 
CAGTTTGCCG GCCTTAACCA GCTTATATGG CTTTATCTTG ACCATAATTA CATTAGCTCA 
GTGGATGAAG ATGCATTTCA AGGGATCCGT AGACTGAAAG AATTAATTCT AAGCTCCAAC 
AAAATTACTT ATCTGCACAA TAAAACATTT CACCCAGTTC CCAATCTCCG CAATCTGGAC 
CTCTCCTACA ATAAGCTTCA GACATTGCAA TCTGAACAAT TTAAAGGCCT TCGGAAACTC 
ATCATTTTGC ACTTGAGATC TAACTCACTA AAGACTGTGC CCATAAGAGT TTTTCAAGAC 
TGTCGGAATC TTGATTTTTT GGATTTGGGT TACAATCGTC TTCGAAGCTT GTCCCGAAAT 
GCATTTGCTG GCCTCTTGAA GTTAAAGGAG CTCCACCTGG AGCACAACCA GTTTTCCAAG 
ATCAACTTTG CTCATTTTCC ACGTCTCTTC AACCTCCGCT CAATTTACTT ACAATGGAAC 
AGGATTCGCT CCATTAGCCA AGGTTTGACA TGGACTTGGA GTTCCTTACA CAACTTGGAT 
TTATCAGGGA ATGACATCCA AGGAATTGAG CCGGGCACAT TTAAATGCCT CCCCAATTTA 
CAAAAATTGA ATTTGGATTC CAACAAGCTC ACCAATATCT CACAGGAAAC TGTCAATGCG 
TGGATATCAT TAATATCCAT CACATTGTCT GGAAATATGT GGGAATGCAG TCGGAGCATT 
TGTCCTTTAT TTTATTGGCT TAAGAATTTC AAAGGAAATA AGGAAAGCAC CATGATATGT 
GCGGGACCTA AGCACATCCA GGGTGAAAAG GTTAGTGATG CAGTGGAAAC ATATAATATC 
TGTTCTGAAG TCCAGGTGGT CAACACAGAA AGATCACACC TGGTGCCCCA AACTCCCCAG 
AAACCTCTGA TTATCCCTAG ACCTACCATC TTCAAACCTG ACGTCACCCA ATCCACCTTT 
GAAACACCAA GCCCTTCCCC AGGGTTTCAG ATTCCTGGCG CAGAGCAAGA GTATGAGCAT 
GTTTCATTTC ACAAAATTAT TGCCGGGAGT GTGGCTCTCT TTCTCTCAGT GGCCATGATC 
CTCTTGGTGA TCTATGTGTC TTGGAAACGC TACCCAGCCA GCATGAAACA ACTCCAGCAA 
CACTCTCTTA TGAAGAGGCG GCGGAAAAAG GCCAGAGAGT CTGAAAGACA AATGAATTCC 
CCTTTACAGG AGTATTATGT GGACTACAAG CCTACAAACT CTGAGACCAT GGATATATCG 
GTTAATGGAT CTGGGCCCTG CACATATACC ATCTCTGGCT CCAGGGAATG TGAGATGCCA 
CACCACATGA AGCCCTTGCC ATATTACAGC TATGACCAGC CTGTGATCGG GTACTGCCAG 
GCCCACCAGC CACTCCATGT CACCAAGGGC TATGAGACAG TGTCTCCAGA GCAGGACGAA 
AGCCCCGGCC TGGAGCTGGG CCGAGACCAC AGCTTCATCG CCACCATCGC CAGGTCGGCA 
GCACCGGCCA TCTACCTAGA GAGAATTGCA AACTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001317299.1
CDS	319..2094
Translation	MPGFHLITQLKGMSVVLVLLPTLLLVMLTGAQRACPKNCRCDGKIVYCESHAFADIPENISGGSQGLSLRFNSIQKLKSNQFAGLNQLIWLYLDHNYISSVDEDAFQGIRRLKELILSSNKITYLHNKTFHPVPNLRNLDLSYNKLQTLQSEQFKGLRKLIILHLRSNSLKTVPIRVFQDCRNLDFLDLGYNRLRSLSRNAFAGLLKLKELHLEHNQFSKINFAHFPRLFNLRSIYLQWNRIRSISQGLTWTWSSLHNLDLSGNDIQGIEPGTFKCLPNLQKLNLDSNKLTNISQETVNAWISLISITLSGNMWECSRSICPLFYWLKNFKGNKESTMICAGPKHIQGEKVSDAVETYNICSEVQVVNTERSHLVPQTPQKPLIIPRPTIFKPDVTQSTFETPSPSPGFQIPGAEQEYEHVSFHKIIAGSVALFLSVAMILLVIYVSWKRYPASMKQLQQHSLMKRRRKKARESERQMNSPLQEYYVDYKPTNSETMDISVNGSGPCTYTISGSRECEMPHHMKPLPYYSYDQPVIGYCQAHQPLHVTKGYETVSPEQDESPGLELGRDHSFIATIARSAAPAIYLERIAN

Target ORF information:

RefSeq Version	NM_001330370.1
Organism	Homo sapiens(human)
Definition	Homo sapiens leucine rich repeat transmembrane neuronal 4 (LRRTM4), transcript variant 5, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001330370.1

ORF Insert Sequence:

ATGCCAGGTT TCCATTTAAT TACGCAGCTG AAAGGCATGA GTGTGGTGCT GGTGCTACTT 
CCTACACTGC TGCTTGTTAT GCTCACGGGT GCTCAGAGAG CTTGCCCAAA GAACTGCAGA 
TGTGATGGCA AAATTGTGTA CTGTGAGTCT CATGCTTTCG CAGATATCCC TGAGAACATT 
TCTGGAGGGT CACAAGGCTT ATCATTAAGG TTCAACAGCA TTCAGAAGCT CAAATCCAAT 
CAGTTTGCCG GCCTTAACCA GCTTATATGG CTTTATCTTG ACCATAATTA CATTAGCTCA 
GTGGATGAAG ATGCATTTCA AGGGATCCGT AGACTGAAAG AATTAATTCT AAGCTCCAAC 
AAAATTACTT ATCTGCACAA TAAAACATTT CACCCAGTTC CCAATCTCCG CAATCTGGAC 
CTCTCCTACA ATAAGCTTCA GACATTGCAA TCTGAACAAT TTAAAGGCCT TCGGAAACTC 
ATCATTTTGC ACTTGAGATC TAACTCACTA AAGACTGTGC CCATAAGAGT TTTTCAAGAC 
TGTCGGAATC TTGATTTTTT GGATTTGGGT TACAATCGTC TTCGAAGCTT GTCCCGAAAT 
GCATTTGCTG GCCTCTTGAA GTTAAAGGAG CTCCACCTGG AGCACAACCA GTTTTCCAAG 
ATCAACTTTG CTCATTTTCC ACGTCTCTTC AACCTCCGCT CAATTTACTT ACAATGGAAC 
AGGATTCGCT CCATTAGCCA AGGTTTGACA TGGACTTGGA GTTCCTTACA CAACTTGGAT 
TTATCAGGGA ATGACATCCA AGGAATTGAG CCGGGCACAT TTAAATGCCT CCCCAATTTA 
CAAAAATTGA ATTTGGATTC CAACAAGCTC ACCAATATCT CACAGGAAAC TGTCAATGCG 
TGGATATCAT TAATATCCAT CACATTGTCT GGAAATATGT GGGAATGCAG TCGGAGCATT 
TGTCCTTTAT TTTATTGGCT TAAGAATTTC AAAGGAAATA AGGAAAGCAC CATGATATGT 
GCGGGACCTA AGCACATCCA GGGTGAAAAG GTTAGTGATG CAGTGGAAAC ATATAATATC 
TGTTCTGAAG TCCAGGTGGT CAACACAGAA AGATCACACC TGGTGCCCCA AACTCCCCAG 
AAACCTCTGA TTATCCCTAG ACCTACCATC TTCAAACCTG ACGTCACCCA ATCCACCTTT 
GAAACACCAA GCCCTTCCCC AGGGTTTCAG ATTCCTGGCG CAGAGCAAGA GTATGAGCAT 
GTTTCATTTC ACAAAATTAT TGCCGGGAGT GTGGCTCTCT TTCTCTCAGT GGCCATGATC 
CTCTTGGTGA TCTATGTGTC TTGGAAACGC TACCCAGCCA GCATGAAACA ACTCCAGCAA 
CACTCTCTTA TGAAGAGGCG GCGGAAAAAG GCCAGAGAGT CTGAAAGACA AATGAATTCC 
CCTTTACAGG AGTATTATGT GGACTACAAG CCTACAAACT CTGAGACCAT GGATATATCG 
GTTAATGGAT CTGGGCCCTG CACATATACC ATCTCTGGCT CCAGGGAATG TGAGATGCCA 
CACCACATGA AGCCCTTGCC ATATTACAGC TATGACCAGC CTGTGATCGG GTACTGCCAG 
GCCCACCAGC CACTCCATGT CACCAAGGGC TATGAGACAG TGTCTCCAGA GCAGGACGAA 
AGCCCCGGCC TGGAGCTGGG CCGAGACCAC AGCTTCATCG CCACCATCGC CAGGTCGGCA 
GCACCGGCCA TCTACCTAGA GAGAATTGCA AACTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Unbiased discovery of glypican as a receptor for LRRTM4 in regulating excitatory synapse development.
Neuron79(4)696-711(2013 Aug)
de Wit J,O'Sullivan ML,Savas JN,Condomitti G,Caccese MC,Vennekens KM,Yates JR 3rd,Ghosh A

A novel gene family encoding leucine-rich repeat transmembrane proteins differentially expressed in the nervous system.
Genomics81(4)411-21(2003 Apr)
Laur?n J,Airaksinen MS,Saarma M,Timmusk T

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LRRTM4 cDNA ORF clone, Homo sapiens(human)

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Clones

gRNAs

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Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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