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GDF5 cDNA ORF clone, Homo sapiens(Human)

Summary

Gene Symbol GDF5
Entrez Gene ID 8200
Full Name growth differentiation factor 5
Synonyms BDA1C,BMP-14,BMP14,CDMP1,LAP-4,LAP4,OS5,SYM1B,SYNS2
General protein information
Preferred Names

growth differentiation factor 5

Names

growth/differentiation factor 5
LPS-associated protein 4
bone morphogenetic protein 14
cartilage-derived morphogenetic protein-1
lipopolysaccharide-associated protein 4
radotermin
Gene Type protein-coding
Organism Homo sapiens(Human)
Genome

20

20q11.22
Summary This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate each subunit of the disulfide-linked homodimer. This protein regulates the development of numerous tissue and cell types, including cartilage, joints, brown fat, teeth, and the growth of neuronal axons and dendrites. Mutations in this gene are associated with acromesomelic dysplasia, brachydactyly, chondrodysplasia, multiple synostoses syndrome, proximal symphalangism, and susceptibility to osteoarthritis. [provided by RefSeq, Aug 2016].
Disorder MIM:

601146

Disorder Html: ?Acromesomelic dysplasia, Hunter-Thompson type, 201250 (3); Brachydactyly, type C, 113100 (3); Chondrodysplasia, Grebe type, 200700 (3); Du Pan syndrome, 228900 (3); Brachydactyly, type A2, 112600 (3); Symphalangism, proximal, 1B, 615298 (3); Multiple synostoses syndrome 2, 610017 (3); {Osteoarthritis-5}, 612400 (3); Brachydactyly, type A1, C, 615072 (3)

Reference Sequences (RefSeq)

mRNA and Protein(s)

mRNA Protein Name
NM_000557.4 NP_000548.2 growth/differentiation factor 5 preproprotein
XM_011529076.1 XP_011527378.1 growth/differentiation factor 5 isoform X1
NM_000557.5 NP_000548.2 growth/differentiation factor 5 preproprotein
XM_011529075.2 XP_011527377.1 growth/differentiation factor 5 isoform X1
NM_001319138.2 NP_001306067.1 growth/differentiation factor 5 preproprotein
NM_001319138.1 NP_001306067.1 growth/differentiation factor 5 preproprotein
XM_011529075.1 XP_011527377.1 growth/differentiation factor 5 isoform X1

Pathways from BioSystems


Homologies


Gallus gallus (chicken) GDF5 NP_989669.1
Mus musculus (house mouse) Gdf5 NP_032135.2
Xenopus tropicalis (tropical clawed frog) gdf5 NP_001128589.1
Homo sapiens (human) GDF5 NP_000548.1
Rattus norvegicus (Norway rat) Gdf5 XP_003749648.1
Canis lupus familiaris (dog) GDF5 XP_542974.1
Danio rerio (zebrafish) gdf5 XP_002662587.1
Pan troglodytes (chimpanzee) GDF5 XP_530287.2
GDF5 XP_001099806.1
Bos taurus (cattle) GDF5 NP_001179202.1

Gene Ontology

The following GDF5 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the GDF5 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

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***CloneID Accession No. Definition **Vector *Turnaround time Price (USD) Select
OHu28004 NM_001319138.2
Latest version!		 Homo sapiens growth differentiation factor 5 (GDF5), transcript variant 1, mRNA. pcDNA3.1+/C-(K)DYK or customized vector
in pcDNA3.1+/C-(K)DYK		 $189.50-$265.30
$379.00
OHu28004 NM_000557.5
Latest version!		 Homo sapiens growth differentiation factor 5 (GDF5), transcript variant 2, mRNA. pcDNA3.1+/C-(K)DYK or customized vector
in pcDNA3.1+/C-(K)DYK		 $189.50-$265.30
$379.00
OHu28004 XM_011529075.2
Latest version!		 Homo sapiens growth differentiation factor 5 (GDF5), transcript variant X1, mRNA. pcDNA3.1+/C-(K)DYK or customized vector
in pcDNA3.1+/C-(K)DYK		 $189.50-$265.30
$379.00
OHu28004 XM_011529076.1
Latest version!		 Homo sapiens growth differentiation factor 5 (GDF5), transcript variant X2, mRNA. pcDNA3.1+/C-(K)DYK or customized vector
in pcDNA3.1+/C-(K)DYK		 $189.50-$265.30
$379.00
View Old Accession Versions >>
OHu28004 NM_000557.4 Homo sapiens growth differentiation factor 5 (GDF5), transcript variant 2, mRNA. pcDNA3.1+/C-(K)DYK or customized vector
in pcDNA3.1+/C-(K)DYK		 $189.50-$265.30
$379.00
OHu28004 NM_001319138.1 Homo sapiens growth differentiation factor 5 (GDF5), transcript variant 1, mRNA. pcDNA3.1+/C-(K)DYK or customized vector
in pcDNA3.1+/C-(K)DYK		 $189.50-$265.30
$379.00
OHu28004 XM_011529075.1 Homo sapiens growth differentiation factor 5 (GDF5), transcript variant X1, mRNA. pcDNA3.1+/C-(K)DYK or customized vector
in pcDNA3.1+/C-(K)DYK		 $189.50-$265.30
$379.00
Hide Old Accession Versions >>

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)


CloneID OHu28004
Clone ID Related Accession (Same CDS sequence) NM_000557.4 , XM_011529076.1 , NM_000557.5 , XM_011529075.2 , NM_001319138.2 , NM_001319138.1 , XM_011529075.1
Accession Version NM_000557.4 Documents for ORF clone product in default vector
Sequence Information ORF Nucleotide Sequence (Length: 1506bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ™ Seamless cloning technology
Insert Structure linear
Update Date 2017-12-17
Organism Homo sapiens(human)
Product growth/differentiation factor 5 preproprotein
Comment Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from U13660.1, AB593125.1, FO393401.1 and BU625224.1. This sequence is a reference standard in the RefSeqGene project. On Apr 12, 2014 this sequence version replaced NM_000557.3. Transcript Variant: This variant (2) differs in the 5' UTR compared to variant 1. Both variants 1 and 2 encode the same protein. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: U13660.1, AB593125.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1968832, SAMEA2144120 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end. 

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
1501
ATGAGACTCC CCAAACTCCT CACTTTCTTG CTTTGGTACC TGGCTTGGCT GGACCTGGAA 
TTCATCTGCA CTGTGTTGGG TGCCCCTGAC TTGGGCCAGA GACCCCAGGG GACCAGGCCA 
GGATTGGCCA AAGCAGAGGC CAAGGAGAGG CCCCCCCTGG CCCGGAACGT CTTCAGGCCA 
GGGGGTCACA GCTATGGTGG GGGGGCCACC AATGCCAATG CCAGGGCAAA GGGAGGCACC 
GGGCAGACAG GAGGCCTGAC ACAGCCCAAG AAGGATGAAC CCAAAAAGCT GCCCCCCAGA 
CCGGGCGGCC CTGAACCCAA GCCAGGACAC CCTCCCCAAA CAAGGCAGGC TACAGCCCGG 
ACTGTGACCC CAAAAGGACA GCTTCCCGGA GGCAAGGCAC CCCCAAAAGC AGGATCTGTC 
CCCAGCTCCT TCCTGCTGAA GAAGGCCAGG GAGCCCGGGC CCCCACGAGA GCCCAAGGAG 
CCGTTTCGCC CACCCCCCAT CACACCCCAC GAGTACATGC TCTCGCTGTA CAGGACGCTG 
TCCGATGCTG ACAGAAAGGG AGGCAACAGC AGCGTGAAGT TGGAGGCTGG CCTGGCCAAC 
ACCATCACCA GCTTTATTGA CAAAGGGCAA GATGACCGAG GTCCCGTGGT CAGGAAGCAG 
AGGTACGTGT TTGACATTAG TGCCCTGGAG AAGGATGGGC TGCTGGGGGC CGAGCTGCGG 
ATCTTGCGGA AGAAGCCCTC GGACACGGCC AAGCCAGCGG CCCCCGGAGG CGGGCGGGCT 
GCCCAGCTGA AGCTGTCCAG CTGCCCCAGC GGCCGGCAGC CGGCCGCCTT GCTGGATGTG 
CGCTCCGTGC CAGGCCTGGA CGGATCTGGC TGGGAGGTGT TCGACATCTG GAAGCTCTTC 
CGAAACTTTA AGAACTCGGC CCAGCTGTGC CTGGAGCTGG AGGCCTGGGA ACGGGGCAGG 
GCCGTGGACC TCCGTGGCCT GGGCTTCGAC CGCGCCGCCC GGCAGGTCCA CGAGAAAGCC 
CTGTTCCTGG TGTTTGGCCG CACCAAGAAA CGGGACCTGT TCTTTAATGA GATTAAGGCC 
CGCTCTGGCC AGGACGATAA GACCGTGTAT GAGTACCTGT TCAGCCAGCG GCGAAAACGG 
CGGGCCCCAC TGGCCACTCG CCAGGGCAAG CGACCCAGCA AGAACCTTAA GGCTCGCTGC 
AGTCGGAAGG CACTGCATGT CAACTTCAAG GACATGGGCT GGGACGACTG GATCATCGCA 
CCCCTTGAGT ACGAGGCTTT CCACTGCGAG GGGCTGTGCG AGTTCCCATT GCGCTCCCAC 
CTGGAGCCCA CGAATCATGC AGTCATCCAG ACCCTGATGA ACTCCATGGA CCCCGAGTCC 
ACACCACCCA CCTGCTGTGT GCCCACGCGG CTGAGTCCCA TCAGCATCCT CTTCATTGAC 
TCTGCCAACA ACGTGGTGTA TAAGCAGTAT GAGGACATGG TCGTGGAGTC GTGTGGCTGC 
AGGTAG

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq NP_000548.2
CDS263..1768
Translation

Target ORF information:

RefSeq Version NM_000557.4
Organism Homo sapiens(human)
Definition Homo sapiens growth differentiation factor 5 (GDF5), transcript variant 2, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
 NM_000557.4

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
1501
ATGAGACTCC CCAAACTCCT CACTTTCTTG CTTTGGTACC TGGCTTGGCT GGACCTGGAA 
TTCATCTGCA CTGTGTTGGG TGCCCCTGAC TTGGGCCAGA GACCCCAGGG GACCAGGCCA 
GGATTGGCCA AAGCAGAGGC CAAGGAGAGG CCCCCCCTGG CCCGGAACGT CTTCAGGCCA 
GGGGGTCACA GCTATGGTGG GGGGGCCACC AATGCCAATG CCAGGGCAAA GGGAGGCACC 
GGGCAGACAG GAGGCCTGAC ACAGCCCAAG AAGGATGAAC CCAAAAAGCT GCCCCCCAGA 
CCGGGCGGCC CTGAACCCAA GCCAGGACAC CCTCCCCAAA CAAGGCAGGC TACAGCCCGG 
ACTGTGACCC CAAAAGGACA GCTTCCCGGA GGCAAGGCAC CCCCAAAAGC AGGATCTGTC 
CCCAGCTCCT TCCTGCTGAA GAAGGCCAGG GAGCCCGGGC CCCCACGAGA GCCCAAGGAG 
CCGTTTCGCC CACCCCCCAT CACACCCCAC GAGTACATGC TCTCGCTGTA CAGGACGCTG 
TCCGATGCTG ACAGAAAGGG AGGCAACAGC AGCGTGAAGT TGGAGGCTGG CCTGGCCAAC 
ACCATCACCA GCTTTATTGA CAAAGGGCAA GATGACCGAG GTCCCGTGGT CAGGAAGCAG 
AGGTACGTGT TTGACATTAG TGCCCTGGAG AAGGATGGGC TGCTGGGGGC CGAGCTGCGG 
ATCTTGCGGA AGAAGCCCTC GGACACGGCC AAGCCAGCGG CCCCCGGAGG CGGGCGGGCT 
GCCCAGCTGA AGCTGTCCAG CTGCCCCAGC GGCCGGCAGC CGGCCGCCTT GCTGGATGTG 
CGCTCCGTGC CAGGCCTGGA CGGATCTGGC TGGGAGGTGT TCGACATCTG GAAGCTCTTC 
CGAAACTTTA AGAACTCGGC CCAGCTGTGC CTGGAGCTGG AGGCCTGGGA ACGGGGCAGG 
GCCGTGGACC TCCGTGGCCT GGGCTTCGAC CGCGCCGCCC GGCAGGTCCA CGAGAAAGCC 
CTGTTCCTGG TGTTTGGCCG CACCAAGAAA CGGGACCTGT TCTTTAATGA GATTAAGGCC 
CGCTCTGGCC AGGACGATAA GACCGTGTAT GAGTACCTGT TCAGCCAGCG GCGAAAACGG 
CGGGCCCCAC TGGCCACTCG CCAGGGCAAG CGACCCAGCA AGAACCTTAA GGCTCGCTGC 
AGTCGGAAGG CACTGCATGT CAACTTCAAG GACATGGGCT GGGACGACTG GATCATCGCA 
CCCCTTGAGT ACGAGGCTTT CCACTGCGAG GGGCTGTGCG AGTTCCCATT GCGCTCCCAC 
CTGGAGCCCA CGAATCATGC AGTCATCCAG ACCCTGATGA ACTCCATGGA CCCCGAGTCC 
ACACCACCCA CCTGCTGTGT GCCCACGCGG CTGAGTCCCA TCAGCATCCT CTTCATTGAC 
TCTGCCAACA ACGTGGTGTA TAAGCAGTAT GAGGACATGG TCGTGGAGTC GTGTGGCTGC 
AGGTAG

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OHu28004
Clone ID Related Accession (Same CDS sequence) NM_000557.4 , XM_011529076.1 , NM_000557.5 , XM_011529075.2 , NM_001319138.2 , NM_001319138.1 , XM_011529075.1
Accession Version NM_000557.5 Latest version! Documents for ORF clone product in default vector
Sequence Information ORF Nucleotide Sequence (Length: 1506bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ™ Seamless cloning technology
Insert Structure linear
Update Date 2019-08-21
Organism Homo sapiens(human)
Product growth/differentiation factor 5 preproprotein
Comment Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from FO393401.1, U13660.1, AB593125.1 and BU625224.1. This sequence is a reference standard in the RefSeqGene project. On Nov 23, 2018 this sequence version replaced NM_000557.4. Transcript Variant: This variant (2) differs in the 5' UTR compared to variant 1. Both variants 1 and 2 encode the same protein. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: U13660.1, AB593125.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1968832, SAMEA2144120 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000374369.8/ ENSP00000363489.3 RefSeq Select criteria :: based on conservation, expression, longest protein ##RefSeq-Attributes-END## COMPLETENESS: full length. 

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
1501
ATGAGACTCC CCAAACTCCT CACTTTCTTG CTTTGGTACC TGGCTTGGCT GGACCTGGAA 
TTCATCTGCA CTGTGTTGGG TGCCCCTGAC TTGGGCCAGA GACCCCAGGG GACCAGGCCA 
GGATTGGCCA AAGCAGAGGC CAAGGAGAGG CCCCCCCTGG CCCGGAACGT CTTCAGGCCA 
GGGGGTCACA GCTATGGTGG GGGGGCCACC AATGCCAATG CCAGGGCAAA GGGAGGCACC 
GGGCAGACAG GAGGCCTGAC ACAGCCCAAG AAGGATGAAC CCAAAAAGCT GCCCCCCAGA 
CCGGGCGGCC CTGAACCCAA GCCAGGACAC CCTCCCCAAA CAAGGCAGGC TACAGCCCGG 
ACTGTGACCC CAAAAGGACA GCTTCCCGGA GGCAAGGCAC CCCCAAAAGC AGGATCTGTC 
CCCAGCTCCT TCCTGCTGAA GAAGGCCAGG GAGCCCGGGC CCCCACGAGA GCCCAAGGAG 
CCGTTTCGCC CACCCCCCAT CACACCCCAC GAGTACATGC TCTCGCTGTA CAGGACGCTG 
TCCGATGCTG ACAGAAAGGG AGGCAACAGC AGCGTGAAGT TGGAGGCTGG CCTGGCCAAC 
ACCATCACCA GCTTTATTGA CAAAGGGCAA GATGACCGAG GTCCCGTGGT CAGGAAGCAG 
AGGTACGTGT TTGACATTAG TGCCCTGGAG AAGGATGGGC TGCTGGGGGC CGAGCTGCGG 
ATCTTGCGGA AGAAGCCCTC GGACACGGCC AAGCCAGCGG CCCCCGGAGG CGGGCGGGCT 
GCCCAGCTGA AGCTGTCCAG CTGCCCCAGC GGCCGGCAGC CGGCCGCCTT GCTGGATGTG 
CGCTCCGTGC CAGGCCTGGA CGGATCTGGC TGGGAGGTGT TCGACATCTG GAAGCTCTTC 
CGAAACTTTA AGAACTCGGC CCAGCTGTGC CTGGAGCTGG AGGCCTGGGA ACGGGGCAGG 
GCCGTGGACC TCCGTGGCCT GGGCTTCGAC CGCGCCGCCC GGCAGGTCCA CGAGAAAGCC 
CTGTTCCTGG TGTTTGGCCG CACCAAGAAA CGGGACCTGT TCTTTAATGA GATTAAGGCC 
CGCTCTGGCC AGGACGATAA GACCGTGTAT GAGTACCTGT TCAGCCAGCG GCGAAAACGG 
CGGGCCCCAC TGGCCACTCG CCAGGGCAAG CGACCCAGCA AGAACCTTAA GGCTCGCTGC 
AGTCGGAAGG CACTGCATGT CAACTTCAAG GACATGGGCT GGGACGACTG GATCATCGCA 
CCCCTTGAGT ACGAGGCTTT CCACTGCGAG GGGCTGTGCG AGTTCCCATT GCGCTCCCAC 
CTGGAGCCCA CGAATCATGC AGTCATCCAG ACCCTGATGA ACTCCATGGA CCCCGAGTCC 
ACACCACCCA CCTGCTGTGT GCCCACGCGG CTGAGTCCCA TCAGCATCCT CTTCATTGAC 
TCTGCCAACA ACGTGGTGTA TAAGCAGTAT GAGGACATGG TCGTGGAGTC GTGTGGCTGC 
AGGTAG

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq NP_000548.2
CDS301..1806
Translation

Target ORF information:

RefSeq Version NM_000557.5
Organism Homo sapiens(human)
Definition Homo sapiens growth differentiation factor 5 (GDF5), transcript variant 2, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
 NM_000557.5

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
1501
ATGAGACTCC CCAAACTCCT CACTTTCTTG CTTTGGTACC TGGCTTGGCT GGACCTGGAA 
TTCATCTGCA CTGTGTTGGG TGCCCCTGAC TTGGGCCAGA GACCCCAGGG GACCAGGCCA 
GGATTGGCCA AAGCAGAGGC CAAGGAGAGG CCCCCCCTGG CCCGGAACGT CTTCAGGCCA 
GGGGGTCACA GCTATGGTGG GGGGGCCACC AATGCCAATG CCAGGGCAAA GGGAGGCACC 
GGGCAGACAG GAGGCCTGAC ACAGCCCAAG AAGGATGAAC CCAAAAAGCT GCCCCCCAGA 
CCGGGCGGCC CTGAACCCAA GCCAGGACAC CCTCCCCAAA CAAGGCAGGC TACAGCCCGG 
ACTGTGACCC CAAAAGGACA GCTTCCCGGA GGCAAGGCAC CCCCAAAAGC AGGATCTGTC 
CCCAGCTCCT TCCTGCTGAA GAAGGCCAGG GAGCCCGGGC CCCCACGAGA GCCCAAGGAG 
CCGTTTCGCC CACCCCCCAT CACACCCCAC GAGTACATGC TCTCGCTGTA CAGGACGCTG 
TCCGATGCTG ACAGAAAGGG AGGCAACAGC AGCGTGAAGT TGGAGGCTGG CCTGGCCAAC 
ACCATCACCA GCTTTATTGA CAAAGGGCAA GATGACCGAG GTCCCGTGGT CAGGAAGCAG 
AGGTACGTGT TTGACATTAG TGCCCTGGAG AAGGATGGGC TGCTGGGGGC CGAGCTGCGG 
ATCTTGCGGA AGAAGCCCTC GGACACGGCC AAGCCAGCGG CCCCCGGAGG CGGGCGGGCT 
GCCCAGCTGA AGCTGTCCAG CTGCCCCAGC GGCCGGCAGC CGGCCGCCTT GCTGGATGTG 
CGCTCCGTGC CAGGCCTGGA CGGATCTGGC TGGGAGGTGT TCGACATCTG GAAGCTCTTC 
CGAAACTTTA AGAACTCGGC CCAGCTGTGC CTGGAGCTGG AGGCCTGGGA ACGGGGCAGG 
GCCGTGGACC TCCGTGGCCT GGGCTTCGAC CGCGCCGCCC GGCAGGTCCA CGAGAAAGCC 
CTGTTCCTGG TGTTTGGCCG CACCAAGAAA CGGGACCTGT TCTTTAATGA GATTAAGGCC 
CGCTCTGGCC AGGACGATAA GACCGTGTAT GAGTACCTGT TCAGCCAGCG GCGAAAACGG 
CGGGCCCCAC TGGCCACTCG CCAGGGCAAG CGACCCAGCA AGAACCTTAA GGCTCGCTGC 
AGTCGGAAGG CACTGCATGT CAACTTCAAG GACATGGGCT GGGACGACTG GATCATCGCA 
CCCCTTGAGT ACGAGGCTTT CCACTGCGAG GGGCTGTGCG AGTTCCCATT GCGCTCCCAC 
CTGGAGCCCA CGAATCATGC AGTCATCCAG ACCCTGATGA ACTCCATGGA CCCCGAGTCC 
ACACCACCCA CCTGCTGTGT GCCCACGCGG CTGAGTCCCA TCAGCATCCT CTTCATTGAC 
TCTGCCAACA ACGTGGTGTA TAAGCAGTAT GAGGACATGG TCGTGGAGTC GTGTGGCTGC 
AGGTAG

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OHu28004
Clone ID Related Accession (Same CDS sequence) NM_000557.4 , XM_011529076.1 , NM_000557.5 , XM_011529075.2 , NM_001319138.2 , NM_001319138.1 , XM_011529075.1
Accession Version NM_001319138.2 Latest version! Documents for ORF clone product in default vector
Sequence Information ORF Nucleotide Sequence (Length: 1506bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ™ Seamless cloning technology
Insert Structure linear
Update Date 2019-08-06
Organism Homo sapiens(human)
Product growth/differentiation factor 5 preproprotein
Comment Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from FO393401.1, BC032495.1, AB593125.1 and BU625224.1. On May 31, 2019 this sequence version replaced NM_001319138.1. Transcript Variant: This variant (1) represents the longer transcript. Both variants 1 and 2 encode the same protein. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC032495.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1968832, SAMEA2144120 [ECO:0000350] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end. 

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
1501
ATGAGACTCC CCAAACTCCT CACTTTCTTG CTTTGGTACC TGGCTTGGCT GGACCTGGAA 
TTCATCTGCA CTGTGTTGGG TGCCCCTGAC TTGGGCCAGA GACCCCAGGG GACCAGGCCA 
GGATTGGCCA AAGCAGAGGC CAAGGAGAGG CCCCCCCTGG CCCGGAACGT CTTCAGGCCA 
GGGGGTCACA GCTATGGTGG GGGGGCCACC AATGCCAATG CCAGGGCAAA GGGAGGCACC 
GGGCAGACAG GAGGCCTGAC ACAGCCCAAG AAGGATGAAC CCAAAAAGCT GCCCCCCAGA 
CCGGGCGGCC CTGAACCCAA GCCAGGACAC CCTCCCCAAA CAAGGCAGGC TACAGCCCGG 
ACTGTGACCC CAAAAGGACA GCTTCCCGGA GGCAAGGCAC CCCCAAAAGC AGGATCTGTC 
CCCAGCTCCT TCCTGCTGAA GAAGGCCAGG GAGCCCGGGC CCCCACGAGA GCCCAAGGAG 
CCGTTTCGCC CACCCCCCAT CACACCCCAC GAGTACATGC TCTCGCTGTA CAGGACGCTG 
TCCGATGCTG ACAGAAAGGG AGGCAACAGC AGCGTGAAGT TGGAGGCTGG CCTGGCCAAC 
ACCATCACCA GCTTTATTGA CAAAGGGCAA GATGACCGAG GTCCCGTGGT CAGGAAGCAG 
AGGTACGTGT TTGACATTAG TGCCCTGGAG AAGGATGGGC TGCTGGGGGC CGAGCTGCGG 
ATCTTGCGGA AGAAGCCCTC GGACACGGCC AAGCCAGCGG CCCCCGGAGG CGGGCGGGCT 
GCCCAGCTGA AGCTGTCCAG CTGCCCCAGC GGCCGGCAGC CGGCCGCCTT GCTGGATGTG 
CGCTCCGTGC CAGGCCTGGA CGGATCTGGC TGGGAGGTGT TCGACATCTG GAAGCTCTTC 
CGAAACTTTA AGAACTCGGC CCAGCTGTGC CTGGAGCTGG AGGCCTGGGA ACGGGGCAGG 
GCCGTGGACC TCCGTGGCCT GGGCTTCGAC CGCGCCGCCC GGCAGGTCCA CGAGAAAGCC 
CTGTTCCTGG TGTTTGGCCG CACCAAGAAA CGGGACCTGT TCTTTAATGA GATTAAGGCC 
CGCTCTGGCC AGGACGATAA GACCGTGTAT GAGTACCTGT TCAGCCAGCG GCGAAAACGG 
CGGGCCCCAC TGGCCACTCG CCAGGGCAAG CGACCCAGCA AGAACCTTAA GGCTCGCTGC 
AGTCGGAAGG CACTGCATGT CAACTTCAAG GACATGGGCT GGGACGACTG GATCATCGCA 
CCCCTTGAGT ACGAGGCTTT CCACTGCGAG GGGCTGTGCG AGTTCCCATT GCGCTCCCAC 
CTGGAGCCCA CGAATCATGC AGTCATCCAG ACCCTGATGA ACTCCATGGA CCCCGAGTCC 
ACACCACCCA CCTGCTGTGT GCCCACGCGG CTGAGTCCCA TCAGCATCCT CTTCATTGAC 
TCTGCCAACA ACGTGGTGTA TAAGCAGTAT GAGGACATGG TCGTGGAGTC GTGTGGCTGC 
AGGTAG

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq NP_001306067.1
CDS508..2013
Translation

Target ORF information:

RefSeq Version NM_001319138.2
Organism Homo sapiens(human)
Definition Homo sapiens growth differentiation factor 5 (GDF5), transcript variant 1, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
 NM_001319138.2

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
1501
ATGAGACTCC CCAAACTCCT CACTTTCTTG CTTTGGTACC TGGCTTGGCT GGACCTGGAA 
TTCATCTGCA CTGTGTTGGG TGCCCCTGAC TTGGGCCAGA GACCCCAGGG GACCAGGCCA 
GGATTGGCCA AAGCAGAGGC CAAGGAGAGG CCCCCCCTGG CCCGGAACGT CTTCAGGCCA 
GGGGGTCACA GCTATGGTGG GGGGGCCACC AATGCCAATG CCAGGGCAAA GGGAGGCACC 
GGGCAGACAG GAGGCCTGAC ACAGCCCAAG AAGGATGAAC CCAAAAAGCT GCCCCCCAGA 
CCGGGCGGCC CTGAACCCAA GCCAGGACAC CCTCCCCAAA CAAGGCAGGC TACAGCCCGG 
ACTGTGACCC CAAAAGGACA GCTTCCCGGA GGCAAGGCAC CCCCAAAAGC AGGATCTGTC 
CCCAGCTCCT TCCTGCTGAA GAAGGCCAGG GAGCCCGGGC CCCCACGAGA GCCCAAGGAG 
CCGTTTCGCC CACCCCCCAT CACACCCCAC GAGTACATGC TCTCGCTGTA CAGGACGCTG 
TCCGATGCTG ACAGAAAGGG AGGCAACAGC AGCGTGAAGT TGGAGGCTGG CCTGGCCAAC 
ACCATCACCA GCTTTATTGA CAAAGGGCAA GATGACCGAG GTCCCGTGGT CAGGAAGCAG 
AGGTACGTGT TTGACATTAG TGCCCTGGAG AAGGATGGGC TGCTGGGGGC CGAGCTGCGG 
ATCTTGCGGA AGAAGCCCTC GGACACGGCC AAGCCAGCGG CCCCCGGAGG CGGGCGGGCT 
GCCCAGCTGA AGCTGTCCAG CTGCCCCAGC GGCCGGCAGC CGGCCGCCTT GCTGGATGTG 
CGCTCCGTGC CAGGCCTGGA CGGATCTGGC TGGGAGGTGT TCGACATCTG GAAGCTCTTC 
CGAAACTTTA AGAACTCGGC CCAGCTGTGC CTGGAGCTGG AGGCCTGGGA ACGGGGCAGG 
GCCGTGGACC TCCGTGGCCT GGGCTTCGAC CGCGCCGCCC GGCAGGTCCA CGAGAAAGCC 
CTGTTCCTGG TGTTTGGCCG CACCAAGAAA CGGGACCTGT TCTTTAATGA GATTAAGGCC 
CGCTCTGGCC AGGACGATAA GACCGTGTAT GAGTACCTGT TCAGCCAGCG GCGAAAACGG 
CGGGCCCCAC TGGCCACTCG CCAGGGCAAG CGACCCAGCA AGAACCTTAA GGCTCGCTGC 
AGTCGGAAGG CACTGCATGT CAACTTCAAG GACATGGGCT GGGACGACTG GATCATCGCA 
CCCCTTGAGT ACGAGGCTTT CCACTGCGAG GGGCTGTGCG AGTTCCCATT GCGCTCCCAC 
CTGGAGCCCA CGAATCATGC AGTCATCCAG ACCCTGATGA ACTCCATGGA CCCCGAGTCC 
ACACCACCCA CCTGCTGTGT GCCCACGCGG CTGAGTCCCA TCAGCATCCT CTTCATTGAC 
TCTGCCAACA ACGTGGTGTA TAAGCAGTAT GAGGACATGG TCGTGGAGTC GTGTGGCTGC 
AGGTAG

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OHu28004
Clone ID Related Accession (Same CDS sequence) NM_000557.4 , XM_011529076.1 , NM_000557.5 , XM_011529075.2 , NM_001319138.2 , NM_001319138.1 , XM_011529075.1
Accession Version NM_001319138.1 Documents for ORF clone product in default vector
Sequence Information ORF Nucleotide Sequence (Length: 1506bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ™ Seamless cloning technology
Insert Structure linear
Update Date 2019-02-25
Organism Homo sapiens(human)
Product growth/differentiation factor 5 preproprotein
Comment Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from BC032495.1, FO393401.1, AB593125.1 and BU625224.1. On Jan 26, 2016 this sequence version replaced XM_011529076.1. Transcript Variant: This variant (1) represents the longer transcript. Both variants 1 and 2 encode the same protein. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC032495.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1968832, SAMEA2144120 [ECO:0000350] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end. 

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
1501
ATGAGACTCC CCAAACTCCT CACTTTCTTG CTTTGGTACC TGGCTTGGCT GGACCTGGAA 
TTCATCTGCA CTGTGTTGGG TGCCCCTGAC TTGGGCCAGA GACCCCAGGG GACCAGGCCA 
GGATTGGCCA AAGCAGAGGC CAAGGAGAGG CCCCCCCTGG CCCGGAACGT CTTCAGGCCA 
GGGGGTCACA GCTATGGTGG GGGGGCCACC AATGCCAATG CCAGGGCAAA GGGAGGCACC 
GGGCAGACAG GAGGCCTGAC ACAGCCCAAG AAGGATGAAC CCAAAAAGCT GCCCCCCAGA 
CCGGGCGGCC CTGAACCCAA GCCAGGACAC CCTCCCCAAA CAAGGCAGGC TACAGCCCGG 
ACTGTGACCC CAAAAGGACA GCTTCCCGGA GGCAAGGCAC CCCCAAAAGC AGGATCTGTC 
CCCAGCTCCT TCCTGCTGAA GAAGGCCAGG GAGCCCGGGC CCCCACGAGA GCCCAAGGAG 
CCGTTTCGCC CACCCCCCAT CACACCCCAC GAGTACATGC TCTCGCTGTA CAGGACGCTG 
TCCGATGCTG ACAGAAAGGG AGGCAACAGC AGCGTGAAGT TGGAGGCTGG CCTGGCCAAC 
ACCATCACCA GCTTTATTGA CAAAGGGCAA GATGACCGAG GTCCCGTGGT CAGGAAGCAG 
AGGTACGTGT TTGACATTAG TGCCCTGGAG AAGGATGGGC TGCTGGGGGC CGAGCTGCGG 
ATCTTGCGGA AGAAGCCCTC GGACACGGCC AAGCCAGCGG CCCCCGGAGG CGGGCGGGCT 
GCCCAGCTGA AGCTGTCCAG CTGCCCCAGC GGCCGGCAGC CGGCCGCCTT GCTGGATGTG 
CGCTCCGTGC CAGGCCTGGA CGGATCTGGC TGGGAGGTGT TCGACATCTG GAAGCTCTTC 
CGAAACTTTA AGAACTCGGC CCAGCTGTGC CTGGAGCTGG AGGCCTGGGA ACGGGGCAGG 
GCCGTGGACC TCCGTGGCCT GGGCTTCGAC CGCGCCGCCC GGCAGGTCCA CGAGAAAGCC 
CTGTTCCTGG TGTTTGGCCG CACCAAGAAA CGGGACCTGT TCTTTAATGA GATTAAGGCC 
CGCTCTGGCC AGGACGATAA GACCGTGTAT GAGTACCTGT TCAGCCAGCG GCGAAAACGG 
CGGGCCCCAC TGGCCACTCG CCAGGGCAAG CGACCCAGCA AGAACCTTAA GGCTCGCTGC 
AGTCGGAAGG CACTGCATGT CAACTTCAAG GACATGGGCT GGGACGACTG GATCATCGCA 
CCCCTTGAGT ACGAGGCTTT CCACTGCGAG GGGCTGTGCG AGTTCCCATT GCGCTCCCAC 
CTGGAGCCCA CGAATCATGC AGTCATCCAG ACCCTGATGA ACTCCATGGA CCCCGAGTCC 
ACACCACCCA CCTGCTGTGT GCCCACGCGG CTGAGTCCCA TCAGCATCCT CTTCATTGAC 
TCTGCCAACA ACGTGGTGTA TAAGCAGTAT GAGGACATGG TCGTGGAGTC GTGTGGCTGC 
AGGTAG

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq NP_001306067.1
CDS505..2010
Translation

Target ORF information:

RefSeq Version NM_001319138.1
Organism Homo sapiens(human)
Definition Homo sapiens growth differentiation factor 5 (GDF5), transcript variant 1, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
 NM_001319138.1

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
1501
ATGAGACTCC CCAAACTCCT CACTTTCTTG CTTTGGTACC TGGCTTGGCT GGACCTGGAA 
TTCATCTGCA CTGTGTTGGG TGCCCCTGAC TTGGGCCAGA GACCCCAGGG GACCAGGCCA 
GGATTGGCCA AAGCAGAGGC CAAGGAGAGG CCCCCCCTGG CCCGGAACGT CTTCAGGCCA 
GGGGGTCACA GCTATGGTGG GGGGGCCACC AATGCCAATG CCAGGGCAAA GGGAGGCACC 
GGGCAGACAG GAGGCCTGAC ACAGCCCAAG AAGGATGAAC CCAAAAAGCT GCCCCCCAGA 
CCGGGCGGCC CTGAACCCAA GCCAGGACAC CCTCCCCAAA CAAGGCAGGC TACAGCCCGG 
ACTGTGACCC CAAAAGGACA GCTTCCCGGA GGCAAGGCAC CCCCAAAAGC AGGATCTGTC 
CCCAGCTCCT TCCTGCTGAA GAAGGCCAGG GAGCCCGGGC CCCCACGAGA GCCCAAGGAG 
CCGTTTCGCC CACCCCCCAT CACACCCCAC GAGTACATGC TCTCGCTGTA CAGGACGCTG 
TCCGATGCTG ACAGAAAGGG AGGCAACAGC AGCGTGAAGT TGGAGGCTGG CCTGGCCAAC 
ACCATCACCA GCTTTATTGA CAAAGGGCAA GATGACCGAG GTCCCGTGGT CAGGAAGCAG 
AGGTACGTGT TTGACATTAG TGCCCTGGAG AAGGATGGGC TGCTGGGGGC CGAGCTGCGG 
ATCTTGCGGA AGAAGCCCTC GGACACGGCC AAGCCAGCGG CCCCCGGAGG CGGGCGGGCT 
GCCCAGCTGA AGCTGTCCAG CTGCCCCAGC GGCCGGCAGC CGGCCGCCTT GCTGGATGTG 
CGCTCCGTGC CAGGCCTGGA CGGATCTGGC TGGGAGGTGT TCGACATCTG GAAGCTCTTC 
CGAAACTTTA AGAACTCGGC CCAGCTGTGC CTGGAGCTGG AGGCCTGGGA ACGGGGCAGG 
GCCGTGGACC TCCGTGGCCT GGGCTTCGAC CGCGCCGCCC GGCAGGTCCA CGAGAAAGCC 
CTGTTCCTGG TGTTTGGCCG CACCAAGAAA CGGGACCTGT TCTTTAATGA GATTAAGGCC 
CGCTCTGGCC AGGACGATAA GACCGTGTAT GAGTACCTGT TCAGCCAGCG GCGAAAACGG 
CGGGCCCCAC TGGCCACTCG CCAGGGCAAG CGACCCAGCA AGAACCTTAA GGCTCGCTGC 
AGTCGGAAGG CACTGCATGT CAACTTCAAG GACATGGGCT GGGACGACTG GATCATCGCA 
CCCCTTGAGT ACGAGGCTTT CCACTGCGAG GGGCTGTGCG AGTTCCCATT GCGCTCCCAC 
CTGGAGCCCA CGAATCATGC AGTCATCCAG ACCCTGATGA ACTCCATGGA CCCCGAGTCC 
ACACCACCCA CCTGCTGTGT GCCCACGCGG CTGAGTCCCA TCAGCATCCT CTTCATTGAC 
TCTGCCAACA ACGTGGTGTA TAAGCAGTAT GAGGACATGG TCGTGGAGTC GTGTGGCTGC 
AGGTAG

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OHu28004
Clone ID Related Accession (Same CDS sequence) NM_000557.4 , XM_011529076.1 , NM_000557.5 , XM_011529075.2 , NM_001319138.2 , NM_001319138.1 , XM_011529075.1
Accession Version XM_011529076.1 Latest version! Documents for ORF clone product in default vector
Sequence Information ORF Nucleotide Sequence (Length: 1506bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ™ Seamless cloning technology
Insert Structure linear
Update Date 2015-03-11
Organism Homo sapiens(Human)
Product growth/differentiation factor 5 isoform X1
Comment 

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
1501
ATGAGACTCC CCAAACTCCT CACTTTCTTG CTTTGGTACC TGGCTTGGCT GGACCTGGAA 
TTCATCTGCA CTGTGTTGGG TGCCCCTGAC TTGGGCCAGA GACCCCAGGG GACCAGGCCA 
GGATTGGCCA AAGCAGAGGC CAAGGAGAGG CCCCCCCTGG CCCGGAACGT CTTCAGGCCA 
GGGGGTCACA GCTATGGTGG GGGGGCCACC AATGCCAATG CCAGGGCAAA GGGAGGCACC 
GGGCAGACAG GAGGCCTGAC ACAGCCCAAG AAGGATGAAC CCAAAAAGCT GCCCCCCAGA 
CCGGGCGGCC CTGAACCCAA GCCAGGACAC CCTCCCCAAA CAAGGCAGGC TACAGCCCGG 
ACTGTGACCC CAAAAGGACA GCTTCCCGGA GGCAAGGCAC CCCCAAAAGC AGGATCTGTC 
CCCAGCTCCT TCCTGCTGAA GAAGGCCAGG GAGCCCGGGC CCCCACGAGA GCCCAAGGAG 
CCGTTTCGCC CACCCCCCAT CACACCCCAC GAGTACATGC TCTCGCTGTA CAGGACGCTG 
TCCGATGCTG ACAGAAAGGG AGGCAACAGC AGCGTGAAGT TGGAGGCTGG CCTGGCCAAC 
ACCATCACCA GCTTTATTGA CAAAGGGCAA GATGACCGAG GTCCCGTGGT CAGGAAGCAG 
AGGTACGTGT TTGACATTAG TGCCCTGGAG AAGGATGGGC TGCTGGGGGC CGAGCTGCGG 
ATCTTGCGGA AGAAGCCCTC GGACACGGCC AAGCCAGCGG CCCCCGGAGG CGGGCGGGCT 
GCCCAGCTGA AGCTGTCCAG CTGCCCCAGC GGCCGGCAGC CGGCCGCCTT GCTGGATGTG 
CGCTCCGTGC CAGGCCTGGA CGGATCTGGC TGGGAGGTGT TCGACATCTG GAAGCTCTTC 
CGAAACTTTA AGAACTCGGC CCAGCTGTGC CTGGAGCTGG AGGCCTGGGA ACGGGGCAGG 
GCCGTGGACC TCCGTGGCCT GGGCTTCGAC CGCGCCGCCC GGCAGGTCCA CGAGAAAGCC 
CTGTTCCTGG TGTTTGGCCG CACCAAGAAA CGGGACCTGT TCTTTAATGA GATTAAGGCC 
CGCTCTGGCC AGGACGATAA GACCGTGTAT GAGTACCTGT TCAGCCAGCG GCGAAAACGG 
CGGGCCCCAC TGGCCACTCG CCAGGGCAAG CGACCCAGCA AGAACCTTAA GGCTCGCTGC 
AGTCGGAAGG CACTGCATGT CAACTTCAAG GACATGGGCT GGGACGACTG GATCATCGCA 
CCCCTTGAGT ACGAGGCTTT CCACTGCGAG GGGCTGTGCG AGTTCCCATT GCGCTCCCAC 
CTGGAGCCCA CGAATCATGC AGTCATCCAG ACCCTGATGA ACTCCATGGA CCCCGAGTCC 
ACACCACCCA CCTGCTGTGT GCCCACGCGG CTGAGTCCCA TCAGCATCCT CTTCATTGAC 
TCTGCCAACA ACGTGGTGTA TAAGCAGTAT GAGGACATGG TCGTGGAGTC GTGTGGCTGC 
AGGTAG

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq XP_011527378.1
Translation

Target ORF information:

RefSeq Version XM_011529076.1
Organism Homo sapiens(Human)
Definition Homo sapiens growth differentiation factor 5 (GDF5), transcript variant X2, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
 XM_011529076.1

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
1501
ATGAGACTCC CCAAACTCCT CACTTTCTTG CTTTGGTACC TGGCTTGGCT GGACCTGGAA 
TTCATCTGCA CTGTGTTGGG TGCCCCTGAC TTGGGCCAGA GACCCCAGGG GACCAGGCCA 
GGATTGGCCA AAGCAGAGGC CAAGGAGAGG CCCCCCCTGG CCCGGAACGT CTTCAGGCCA 
GGGGGTCACA GCTATGGTGG GGGGGCCACC AATGCCAATG CCAGGGCAAA GGGAGGCACC 
GGGCAGACAG GAGGCCTGAC ACAGCCCAAG AAGGATGAAC CCAAAAAGCT GCCCCCCAGA 
CCGGGCGGCC CTGAACCCAA GCCAGGACAC CCTCCCCAAA CAAGGCAGGC TACAGCCCGG 
ACTGTGACCC CAAAAGGACA GCTTCCCGGA GGCAAGGCAC CCCCAAAAGC AGGATCTGTC 
CCCAGCTCCT TCCTGCTGAA GAAGGCCAGG GAGCCCGGGC CCCCACGAGA GCCCAAGGAG 
CCGTTTCGCC CACCCCCCAT CACACCCCAC GAGTACATGC TCTCGCTGTA CAGGACGCTG 
TCCGATGCTG ACAGAAAGGG AGGCAACAGC AGCGTGAAGT TGGAGGCTGG CCTGGCCAAC 
ACCATCACCA GCTTTATTGA CAAAGGGCAA GATGACCGAG GTCCCGTGGT CAGGAAGCAG 
AGGTACGTGT TTGACATTAG TGCCCTGGAG AAGGATGGGC TGCTGGGGGC CGAGCTGCGG 
ATCTTGCGGA AGAAGCCCTC GGACACGGCC AAGCCAGCGG CCCCCGGAGG CGGGCGGGCT 
GCCCAGCTGA AGCTGTCCAG CTGCCCCAGC GGCCGGCAGC CGGCCGCCTT GCTGGATGTG 
CGCTCCGTGC CAGGCCTGGA CGGATCTGGC TGGGAGGTGT TCGACATCTG GAAGCTCTTC 
CGAAACTTTA AGAACTCGGC CCAGCTGTGC CTGGAGCTGG AGGCCTGGGA ACGGGGCAGG 
GCCGTGGACC TCCGTGGCCT GGGCTTCGAC CGCGCCGCCC GGCAGGTCCA CGAGAAAGCC 
CTGTTCCTGG TGTTTGGCCG CACCAAGAAA CGGGACCTGT TCTTTAATGA GATTAAGGCC 
CGCTCTGGCC AGGACGATAA GACCGTGTAT GAGTACCTGT TCAGCCAGCG GCGAAAACGG 
CGGGCCCCAC TGGCCACTCG CCAGGGCAAG CGACCCAGCA AGAACCTTAA GGCTCGCTGC 
AGTCGGAAGG CACTGCATGT CAACTTCAAG GACATGGGCT GGGACGACTG GATCATCGCA 
CCCCTTGAGT ACGAGGCTTT CCACTGCGAG GGGCTGTGCG AGTTCCCATT GCGCTCCCAC 
CTGGAGCCCA CGAATCATGC AGTCATCCAG ACCCTGATGA ACTCCATGGA CCCCGAGTCC 
ACACCACCCA CCTGCTGTGT GCCCACGCGG CTGAGTCCCA TCAGCATCCT CTTCATTGAC 
TCTGCCAACA ACGTGGTGTA TAAGCAGTAT GAGGACATGG TCGTGGAGTC GTGTGGCTGC 
AGGTAG

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OHu28004
Clone ID Related Accession (Same CDS sequence) NM_000557.4 , XM_011529076.1 , NM_000557.5 , XM_011529075.2 , NM_001319138.2 , NM_001319138.1 , XM_011529075.1
Accession Version XM_011529075.2 Latest version! Documents for ORF clone product in default vector
Sequence Information ORF Nucleotide Sequence (Length: 1506bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ™ Seamless cloning technology
Insert Structure linear
Update Date 2016-06-05
Organism Homo sapiens(human)
Product growth/differentiation factor 5 isoform X1
Comment Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000020.11) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 6, 2016 this sequence version replaced XM_011529075.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Homo sapiens Annotation Release 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## 

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
1501
ATGAGACTCC CCAAACTCCT CACTTTCTTG CTTTGGTACC TGGCTTGGCT GGACCTGGAA 
TTCATCTGCA CTGTGTTGGG TGCCCCTGAC TTGGGCCAGA GACCCCAGGG GACCAGGCCA 
GGATTGGCCA AAGCAGAGGC CAAGGAGAGG CCCCCCCTGG CCCGGAACGT CTTCAGGCCA 
GGGGGTCACA GCTATGGTGG GGGGGCCACC AATGCCAATG CCAGGGCAAA GGGAGGCACC 
GGGCAGACAG GAGGCCTGAC ACAGCCCAAG AAGGATGAAC CCAAAAAGCT GCCCCCCAGA 
CCGGGCGGCC CTGAACCCAA GCCAGGACAC CCTCCCCAAA CAAGGCAGGC TACAGCCCGG 
ACTGTGACCC CAAAAGGACA GCTTCCCGGA GGCAAGGCAC CCCCAAAAGC AGGATCTGTC 
CCCAGCTCCT TCCTGCTGAA GAAGGCCAGG GAGCCCGGGC CCCCACGAGA GCCCAAGGAG 
CCGTTTCGCC CACCCCCCAT CACACCCCAC GAGTACATGC TCTCGCTGTA CAGGACGCTG 
TCCGATGCTG ACAGAAAGGG AGGCAACAGC AGCGTGAAGT TGGAGGCTGG CCTGGCCAAC 
ACCATCACCA GCTTTATTGA CAAAGGGCAA GATGACCGAG GTCCCGTGGT CAGGAAGCAG 
AGGTACGTGT TTGACATTAG TGCCCTGGAG AAGGATGGGC TGCTGGGGGC CGAGCTGCGG 
ATCTTGCGGA AGAAGCCCTC GGACACGGCC AAGCCAGCGG CCCCCGGAGG CGGGCGGGCT 
GCCCAGCTGA AGCTGTCCAG CTGCCCCAGC GGCCGGCAGC CGGCCGCCTT GCTGGATGTG 
CGCTCCGTGC CAGGCCTGGA CGGATCTGGC TGGGAGGTGT TCGACATCTG GAAGCTCTTC 
CGAAACTTTA AGAACTCGGC CCAGCTGTGC CTGGAGCTGG AGGCCTGGGA ACGGGGCAGG 
GCCGTGGACC TCCGTGGCCT GGGCTTCGAC CGCGCCGCCC GGCAGGTCCA CGAGAAAGCC 
CTGTTCCTGG TGTTTGGCCG CACCAAGAAA CGGGACCTGT TCTTTAATGA GATTAAGGCC 
CGCTCTGGCC AGGACGATAA GACCGTGTAT GAGTACCTGT TCAGCCAGCG GCGAAAACGG 
CGGGCCCCAC TGGCCACTCG CCAGGGCAAG CGACCCAGCA AGAACCTTAA GGCTCGCTGC 
AGTCGGAAGG CACTGCATGT CAACTTCAAG GACATGGGCT GGGACGACTG GATCATCGCA 
CCCCTTGAGT ACGAGGCTTT CCACTGCGAG GGGCTGTGCG AGTTCCCATT GCGCTCCCAC 
CTGGAGCCCA CGAATCATGC AGTCATCCAG ACCCTGATGA ACTCCATGGA CCCCGAGTCC 
ACACCACCCA CCTGCTGTGT GCCCACGCGG CTGAGTCCCA TCAGCATCCT CTTCATTGAC 
TCTGCCAACA ACGTGGTGTA TAAGCAGTAT GAGGACATGG TCGTGGAGTC GTGTGGCTGC 
AGGTAG

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq XP_011527377.1
CDS395..1900
Translation

Target ORF information:

RefSeq Version XM_011529075.2
Organism Homo sapiens(human)
Definition Homo sapiens growth differentiation factor 5 (GDF5), transcript variant X1, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
 XM_011529075.2

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
1501
ATGAGACTCC CCAAACTCCT CACTTTCTTG CTTTGGTACC TGGCTTGGCT GGACCTGGAA 
TTCATCTGCA CTGTGTTGGG TGCCCCTGAC TTGGGCCAGA GACCCCAGGG GACCAGGCCA 
GGATTGGCCA AAGCAGAGGC CAAGGAGAGG CCCCCCCTGG CCCGGAACGT CTTCAGGCCA 
GGGGGTCACA GCTATGGTGG GGGGGCCACC AATGCCAATG CCAGGGCAAA GGGAGGCACC 
GGGCAGACAG GAGGCCTGAC ACAGCCCAAG AAGGATGAAC CCAAAAAGCT GCCCCCCAGA 
CCGGGCGGCC CTGAACCCAA GCCAGGACAC CCTCCCCAAA CAAGGCAGGC TACAGCCCGG 
ACTGTGACCC CAAAAGGACA GCTTCCCGGA GGCAAGGCAC CCCCAAAAGC AGGATCTGTC 
CCCAGCTCCT TCCTGCTGAA GAAGGCCAGG GAGCCCGGGC CCCCACGAGA GCCCAAGGAG 
CCGTTTCGCC CACCCCCCAT CACACCCCAC GAGTACATGC TCTCGCTGTA CAGGACGCTG 
TCCGATGCTG ACAGAAAGGG AGGCAACAGC AGCGTGAAGT TGGAGGCTGG CCTGGCCAAC 
ACCATCACCA GCTTTATTGA CAAAGGGCAA GATGACCGAG GTCCCGTGGT CAGGAAGCAG 
AGGTACGTGT TTGACATTAG TGCCCTGGAG AAGGATGGGC TGCTGGGGGC CGAGCTGCGG 
ATCTTGCGGA AGAAGCCCTC GGACACGGCC AAGCCAGCGG CCCCCGGAGG CGGGCGGGCT 
GCCCAGCTGA AGCTGTCCAG CTGCCCCAGC GGCCGGCAGC CGGCCGCCTT GCTGGATGTG 
CGCTCCGTGC CAGGCCTGGA CGGATCTGGC TGGGAGGTGT TCGACATCTG GAAGCTCTTC 
CGAAACTTTA AGAACTCGGC CCAGCTGTGC CTGGAGCTGG AGGCCTGGGA ACGGGGCAGG 
GCCGTGGACC TCCGTGGCCT GGGCTTCGAC CGCGCCGCCC GGCAGGTCCA CGAGAAAGCC 
CTGTTCCTGG TGTTTGGCCG CACCAAGAAA CGGGACCTGT TCTTTAATGA GATTAAGGCC 
CGCTCTGGCC AGGACGATAA GACCGTGTAT GAGTACCTGT TCAGCCAGCG GCGAAAACGG 
CGGGCCCCAC TGGCCACTCG CCAGGGCAAG CGACCCAGCA AGAACCTTAA GGCTCGCTGC 
AGTCGGAAGG CACTGCATGT CAACTTCAAG GACATGGGCT GGGACGACTG GATCATCGCA 
CCCCTTGAGT ACGAGGCTTT CCACTGCGAG GGGCTGTGCG AGTTCCCATT GCGCTCCCAC 
CTGGAGCCCA CGAATCATGC AGTCATCCAG ACCCTGATGA ACTCCATGGA CCCCGAGTCC 
ACACCACCCA CCTGCTGTGT GCCCACGCGG CTGAGTCCCA TCAGCATCCT CTTCATTGAC 
TCTGCCAACA ACGTGGTGTA TAAGCAGTAT GAGGACATGG TCGTGGAGTC GTGTGGCTGC 
AGGTAG

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OHu28004
Clone ID Related Accession (Same CDS sequence) NM_000557.4 , XM_011529076.1 , NM_000557.5 , XM_011529075.2 , NM_001319138.2 , NM_001319138.1 , XM_011529075.1
Accession Version XM_011529075.1 Documents for ORF clone product in default vector
Sequence Information ORF Nucleotide Sequence (Length: 1506bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ™ Seamless cloning technology
Insert Structure linear
Update Date 2015-03-11
Organism Homo sapiens(Human)
Product growth/differentiation factor 5 isoform X1
Comment 

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
1501
ATGAGACTCC CCAAACTCCT CACTTTCTTG CTTTGGTACC TGGCTTGGCT GGACCTGGAA 
TTCATCTGCA CTGTGTTGGG TGCCCCTGAC TTGGGCCAGA GACCCCAGGG GACCAGGCCA 
GGATTGGCCA AAGCAGAGGC CAAGGAGAGG CCCCCCCTGG CCCGGAACGT CTTCAGGCCA 
GGGGGTCACA GCTATGGTGG GGGGGCCACC AATGCCAATG CCAGGGCAAA GGGAGGCACC 
GGGCAGACAG GAGGCCTGAC ACAGCCCAAG AAGGATGAAC CCAAAAAGCT GCCCCCCAGA 
CCGGGCGGCC CTGAACCCAA GCCAGGACAC CCTCCCCAAA CAAGGCAGGC TACAGCCCGG 
ACTGTGACCC CAAAAGGACA GCTTCCCGGA GGCAAGGCAC CCCCAAAAGC AGGATCTGTC 
CCCAGCTCCT TCCTGCTGAA GAAGGCCAGG GAGCCCGGGC CCCCACGAGA GCCCAAGGAG 
CCGTTTCGCC CACCCCCCAT CACACCCCAC GAGTACATGC TCTCGCTGTA CAGGACGCTG 
TCCGATGCTG ACAGAAAGGG AGGCAACAGC AGCGTGAAGT TGGAGGCTGG CCTGGCCAAC 
ACCATCACCA GCTTTATTGA CAAAGGGCAA GATGACCGAG GTCCCGTGGT CAGGAAGCAG 
AGGTACGTGT TTGACATTAG TGCCCTGGAG AAGGATGGGC TGCTGGGGGC CGAGCTGCGG 
ATCTTGCGGA AGAAGCCCTC GGACACGGCC AAGCCAGCGG CCCCCGGAGG CGGGCGGGCT 
GCCCAGCTGA AGCTGTCCAG CTGCCCCAGC GGCCGGCAGC CGGCCGCCTT GCTGGATGTG 
CGCTCCGTGC CAGGCCTGGA CGGATCTGGC TGGGAGGTGT TCGACATCTG GAAGCTCTTC 
CGAAACTTTA AGAACTCGGC CCAGCTGTGC CTGGAGCTGG AGGCCTGGGA ACGGGGCAGG 
GCCGTGGACC TCCGTGGCCT GGGCTTCGAC CGCGCCGCCC GGCAGGTCCA CGAGAAAGCC 
CTGTTCCTGG TGTTTGGCCG CACCAAGAAA CGGGACCTGT TCTTTAATGA GATTAAGGCC 
CGCTCTGGCC AGGACGATAA GACCGTGTAT GAGTACCTGT TCAGCCAGCG GCGAAAACGG 
CGGGCCCCAC TGGCCACTCG CCAGGGCAAG CGACCCAGCA AGAACCTTAA GGCTCGCTGC 
AGTCGGAAGG CACTGCATGT CAACTTCAAG GACATGGGCT GGGACGACTG GATCATCGCA 
CCCCTTGAGT ACGAGGCTTT CCACTGCGAG GGGCTGTGCG AGTTCCCATT GCGCTCCCAC 
CTGGAGCCCA CGAATCATGC AGTCATCCAG ACCCTGATGA ACTCCATGGA CCCCGAGTCC 
ACACCACCCA CCTGCTGTGT GCCCACGCGG CTGAGTCCCA TCAGCATCCT CTTCATTGAC 
TCTGCCAACA ACGTGGTGTA TAAGCAGTAT GAGGACATGG TCGTGGAGTC GTGTGGCTGC 
AGGTAG

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq XP_011527377.1
Translation

Target ORF information:

RefSeq Version XM_011529075.1
Organism Homo sapiens(Human)
Definition Homo sapiens growth differentiation factor 5 (GDF5), transcript variant X1, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
 XM_011529075.1

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
1501
ATGAGACTCC CCAAACTCCT CACTTTCTTG CTTTGGTACC TGGCTTGGCT GGACCTGGAA 
TTCATCTGCA CTGTGTTGGG TGCCCCTGAC TTGGGCCAGA GACCCCAGGG GACCAGGCCA 
GGATTGGCCA AAGCAGAGGC CAAGGAGAGG CCCCCCCTGG CCCGGAACGT CTTCAGGCCA 
GGGGGTCACA GCTATGGTGG GGGGGCCACC AATGCCAATG CCAGGGCAAA GGGAGGCACC 
GGGCAGACAG GAGGCCTGAC ACAGCCCAAG AAGGATGAAC CCAAAAAGCT GCCCCCCAGA 
CCGGGCGGCC CTGAACCCAA GCCAGGACAC CCTCCCCAAA CAAGGCAGGC TACAGCCCGG 
ACTGTGACCC CAAAAGGACA GCTTCCCGGA GGCAAGGCAC CCCCAAAAGC AGGATCTGTC 
CCCAGCTCCT TCCTGCTGAA GAAGGCCAGG GAGCCCGGGC CCCCACGAGA GCCCAAGGAG 
CCGTTTCGCC CACCCCCCAT CACACCCCAC GAGTACATGC TCTCGCTGTA CAGGACGCTG 
TCCGATGCTG ACAGAAAGGG AGGCAACAGC AGCGTGAAGT TGGAGGCTGG CCTGGCCAAC 
ACCATCACCA GCTTTATTGA CAAAGGGCAA GATGACCGAG GTCCCGTGGT CAGGAAGCAG 
AGGTACGTGT TTGACATTAG TGCCCTGGAG AAGGATGGGC TGCTGGGGGC CGAGCTGCGG 
ATCTTGCGGA AGAAGCCCTC GGACACGGCC AAGCCAGCGG CCCCCGGAGG CGGGCGGGCT 
GCCCAGCTGA AGCTGTCCAG CTGCCCCAGC GGCCGGCAGC CGGCCGCCTT GCTGGATGTG 
CGCTCCGTGC CAGGCCTGGA CGGATCTGGC TGGGAGGTGT TCGACATCTG GAAGCTCTTC 
CGAAACTTTA AGAACTCGGC CCAGCTGTGC CTGGAGCTGG AGGCCTGGGA ACGGGGCAGG 
GCCGTGGACC TCCGTGGCCT GGGCTTCGAC CGCGCCGCCC GGCAGGTCCA CGAGAAAGCC 
CTGTTCCTGG TGTTTGGCCG CACCAAGAAA CGGGACCTGT TCTTTAATGA GATTAAGGCC 
CGCTCTGGCC AGGACGATAA GACCGTGTAT GAGTACCTGT TCAGCCAGCG GCGAAAACGG 
CGGGCCCCAC TGGCCACTCG CCAGGGCAAG CGACCCAGCA AGAACCTTAA GGCTCGCTGC 
AGTCGGAAGG CACTGCATGT CAACTTCAAG GACATGGGCT GGGACGACTG GATCATCGCA 
CCCCTTGAGT ACGAGGCTTT CCACTGCGAG GGGCTGTGCG AGTTCCCATT GCGCTCCCAC 
CTGGAGCCCA CGAATCATGC AGTCATCCAG ACCCTGATGA ACTCCATGGA CCCCGAGTCC 
ACACCACCCA CCTGCTGTGT GCCCACGCGG CTGAGTCCCA TCAGCATCCT CTTCATTGAC 
TCTGCCAACA ACGTGGTGTA TAAGCAGTAT GAGGACATGG TCGTGGAGTC GTGTGGCTGC 
AGGTAG

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

PubMed