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DPY30 cDNA ORF clone, Homo sapiens(human)

Summary

Gene Symbol DPY30
Entrez Gene ID 84661
Full Name dpy-30, histone methyltransferase complex regulatory subunit
Synonyms Cps25,HDPY-30,Saf19
General protein information
Preferred Names

dpy-30, histone methyltransferase complex regulatory subunit

Names

protein dpy-30 homolog
dpy-30 homolog
dpy-30-like protein
dpy-30L
Gene Type protein-coding
Organism Homo sapiens(human)
Genome

2

2p22.3
Summary This gene encodes an integral core subunit of the SET1/MLL family of H3K4 methyltransferases. The encoded protein directly controls cell cycle regulators and plays an important role in the proliferation and differentiation of human hematopoietic progenitor cells. [provided by RefSeq, Mar 2016].
Disorder MIM:

612032


Reference Sequences (RefSeq)

mRNA and Protein(s)

mRNA Protein Name
XM_017005111.1 XP_016860600.1 protein dpy-30 homolog isoform X1
XM_011533133.2 XP_011531435.1 protein dpy-30 homolog isoform X1
NM_032574.3 NP_115963.1 protein dpy-30 homolog isoform 1
XM_006712118.3 XP_006712181.1 protein dpy-30 homolog isoform X1
XM_006712117.4 XP_006712180.1 protein dpy-30 homolog isoform X2
NM_001321210.1 NP_001308139.1 protein dpy-30 homolog isoform 2
NM_032574.2 NP_115963.1 protein dpy-30 homolog
NM_001321209.1 NP_001308138.1 protein dpy-30 homolog isoform 1
XM_006712117.3 XP_006712180.1 protein dpy-30 homolog isoform X2
NM_001321210.2 NP_001308139.1 protein dpy-30 homolog isoform 2
NM_001321209.2 NP_001308138.1 protein dpy-30 homolog isoform 1

Pathways from BioSystems


Homologies


Homo sapiens (human) DPY30 NP_115963.1
Pan troglodytes (chimpanzee) DPY30 XP_001164263.1
DPY30 XP_001105547.1
Bos taurus (cattle) DPY30 NP_001071384.1
Xenopus tropicalis (tropical clawed frog) dpy30 NP_001011017.1
Rattus norvegicus (Norway rat) Dpy30 NP_775140.2
Gallus gallus (chicken) DPY30 NP_001185836.1
Danio rerio (zebrafish) dpy30 NP_001002438.2
Canis lupus familiaris (dog) DPY30 XP_850953.1
Mus musculus (house mouse) Dpy30 NP_001139695.1

Gene Ontology


Bibliography

Related articles in PubMed

PKA-binding domain of AKAP8 is essential for direct interaction with DPY30 protein.
Bieluszewska A, Weglewska M, Bieluszewski T, Lesniewicz K, Poreba E
The FEBS journal(2017 Dec)

Physical Interactions and Functional Coordination between the Core Subunits of Set1/Mll Complexes and the Reprogramming Factors.
Yang Z, Augustin J, Hu J, Jiang H
PloS one10(12)e0145336(2015)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

these results form the basis for understanding how WRAD(DRY-30) differentially regulates SET1 family complexes in vivo.
Title: Biochemical reconstitution and phylogenetic comparison of human SET1 family core complexes involved in histone methylation.

Based on our structural data and cross-linking results, we suggest that Dpy30 may regulate H3K4 methylation according to its copy number in COMPASS
Title: Structural implications of Dpy30 oligomerization for MLL/SET1 COMPASS H3K4 trimethylation.

Dpy30 role in cellular reprogramming and its interactions with Set1 complex
Title: Physical Interactions and Functional Coordination between the Core Subunits of Set1/Mll Complexes and the Reprogramming Factors.

results indicate that DPY30 has critical roles in the proliferation, migration, and invasion of gastric cancer cells, and suggest DPY30 might be a therapeutic target in gastric cancer
Title: Roles of DPY30 in the Proliferation and Motility of Gastric Cancer Cells.

The DPY30 subunit in SET1/MLL complexes regulates the proliferation and differentiation of hematopoietic progenitor cells.
Title: The DPY30 subunit in SET1/MLL complexes regulates the proliferation and differentiation of hematopoietic progenitor cells.

The following DPY30 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the DPY30 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID Accession No. Definition **Vector *Turnaround time Price (USD) Select
OHu17211 NM_001321209.2
Latest version!		 Homo sapiens dpy-30 histone methyltransferase complex regulatory subunit (DPY30), transcript variant 2, mRNA. pcDNA3.1-C-(k)DYK or customized vector
in pcDNA3.1-C-(k)DYK 		$49.50-$69.30
$99.00
OHu17211 NM_032574.3
Latest version!		 Homo sapiens dpy-30 histone methyltransferase complex regulatory subunit (DPY30), transcript variant 1, mRNA. pcDNA3.1-C-(k)DYK or customized vector
in pcDNA3.1-C-(k)DYK 		$49.50-$69.30
$99.00
OHu102045 NM_001321210.2
Latest version!		 Homo sapiens dpy-30 histone methyltransferase complex regulatory subunit (DPY30), transcript variant 3, mRNA. pcDNA3.1-C-(k)DYK or customized vector 7-9 $69.30
$99.00
OHu35634 XM_006712117.4
Latest version!		 Homo sapiens dpy-30 histone methyltransferase complex regulatory subunit (DPY30), transcript variant X3, mRNA. pcDNA3.1-C-(k)DYK or customized vector 7-9 $69.30
$99.00
OHu35635 XM_006712118.3
Latest version!		 Homo sapiens dpy-30 histone methyltransferase complex regulatory subunit (DPY30), transcript variant X1, mRNA. pcDNA3.1-C-(k)DYK or customized vector 7-9 $69.30
$99.00
OHu35635 XM_017005111.1
Latest version!		 Homo sapiens dpy-30 histone methyltransferase complex regulatory subunit (DPY30), transcript variant X2, mRNA. pcDNA3.1-C-(k)DYK or customized vector 7-9 $69.30
$99.00
OHu35635 XM_011533133.2
Latest version!		 Homo sapiens dpy-30 histone methyltransferase complex regulatory subunit (DPY30), transcript variant X4, mRNA. pcDNA3.1-C-(k)DYK or customized vector 7-9 $69.30
$99.00
View Old Accession Versions >>
OHu17211 NM_032574.2 Homo sapiens dpy-30 histone methyltransferase complex regulatory subunit (DPY30), mRNA. pcDNA3.1-C-(k)DYK or customized vector
in pcDNA3.1-C-(k)DYK 		$49.50-$69.30
$99.00
OHu35634 XM_006712117.3 Homo sapiens dpy-30, histone methyltransferase complex regulatory subunit (DPY30), transcript variant X3, mRNA. pcDNA3.1-C-(k)DYK or customized vector 7-9 $69.30
$99.00
OHu102045 NM_001321210.1 Homo sapiens dpy-30 histone methyltransferase complex regulatory subunit (DPY30), transcript variant 3, mRNA. pcDNA3.1-C-(k)DYK or customized vector 7-9 $69.30
$99.00
OHu17211 NM_001321209.1 Homo sapiens dpy-30, histone methyltransferase complex regulatory subunit (DPY30), transcript variant 2, mRNA. pcDNA3.1-C-(k)DYK or customized vector
in pcDNA3.1-C-(k)DYK 		$49.50-$69.30
$99.00
Hide Old Accession Versions >>

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)


CloneID OHu17211
Clone ID Related Accession (Same CDS sequence) NM_032574.3 , NM_032574.2 , NM_001321209.1 , NM_001321209.2
Accession Version NM_032574.3 Latest version! Documents for ORF clone product in default vector
Sequence Information ORF Nucleotide Sequence (Length: 300bp)
Protein sequence
SNP
Vector pcDNA3.1-C-(k)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ™ Seamless cloning technology
Insert Structure linear
Update Date 2019-07-15
Organism Homo sapiens(human)
Product protein dpy-30 homolog isoform 1
Comment Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from BQ276899.1, AL121655.1, AF226998.1 and BM505380.1. On Mar 18, 2016 this sequence version replaced NM_032574.2. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1163658.347831.1, ERR279849.5589.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2158188, SAMEA2467144 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end. 

1
61
121
181
241
ATGGAGCCAG AGCAGATGCT GGAGGGACAA ACGCAGGTTG CAGAAAATCC TCACTCTGAG 
TACGGTCTCA CAGACAACGT TGAGAGAATA GTAGAAAATG AGAAGATTAA TGCAGAAAAG 
TCATCAAAGC AGAAGGTAGA TCTCCAGTCT TTGCCAACTC GTGCCTACCT GGATCAGACA 
GTTGTGCCTA TCTTATTACA GGGACTTGCT GTGCTTGCAA AGGAAAGACC ACCAAATCCC 
ATTGAATTTC TAGCATCTTA TCTTTTAAAA AACAAGGCAC AGTTTGAAGA TCGAAACTGA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq NP_115963.1
CDS280..579
Translation

Target ORF information:

RefSeq Version NM_032574.3
Organism Homo sapiens(human)
Definition Homo sapiens dpy-30 histone methyltransferase complex regulatory subunit (DPY30), transcript variant 1, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
 NM_032574.3

ORF Insert Sequence:

1
61
121
181
241
ATGGAGCCAG AGCAGATGCT GGAGGGACAA ACGCAGGTTG CAGAAAATCC TCACTCTGAG 
TACGGTCTCA CAGACAACGT TGAGAGAATA GTAGAAAATG AGAAGATTAA TGCAGAAAAG 
TCATCAAAGC AGAAGGTAGA TCTCCAGTCT TTGCCAACTC GTGCCTACCT GGATCAGACA 
GTTGTGCCTA TCTTATTACA GGGACTTGCT GTGCTTGCAA AGGAAAGACC ACCAAATCCC 
ATTGAATTTC TAGCATCTTA TCTTTTAAAA AACAAGGCAC AGTTTGAAGA TCGAAACTGA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OHu17211
Clone ID Related Accession (Same CDS sequence) NM_032574.3 , NM_032574.2 , NM_001321209.1 , NM_001321209.2
Accession Version NM_032574.2 Documents for ORF clone product in default vector
Sequence Information ORF Nucleotide Sequence (Length: 300bp)
Protein sequence
SNP
Vector pcDNA3.1-C-(k)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ™ Seamless cloning technology
Insert Structure linear
Update Date 2015-06-20
Organism Homo sapiens(Human)
Product protein dpy-30 homolog
Comment 

1
61
121
181
241
ATGGAGCCAG AGCAGATGCT GGAGGGACAA ACGCAGGTTG CAGAAAATCC TCACTCTGAG 
TACGGTCTCA CAGACAACGT TGAGAGAATA GTAGAAAATG AGAAGATTAA TGCAGAAAAG 
TCATCAAAGC AGAAGGTAGA TCTCCAGTCT TTGCCAACTC GTGCCTACCT GGATCAGACA 
GTTGTGCCTA TCTTATTACA GGGACTTGCT GTGCTTGCAA AGGAAAGACC ACCAAATCCC 
ATTGAATTTC TAGCATCTTA TCTTTTAAAA AACAAGGCAC AGTTTGAAGA TCGAAACTGA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq NP_115963.1
Translation

Target ORF information:

RefSeq Version NM_032574.2
Organism Homo sapiens(Human)
Definition Homo sapiens dpy-30 histone methyltransferase complex regulatory subunit (DPY30), mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
 NM_032574.2

ORF Insert Sequence:

1
61
121
181
241
ATGGAGCCAG AGCAGATGCT GGAGGGACAA ACGCAGGTTG CAGAAAATCC TCACTCTGAG 
TACGGTCTCA CAGACAACGT TGAGAGAATA GTAGAAAATG AGAAGATTAA TGCAGAAAAG 
TCATCAAAGC AGAAGGTAGA TCTCCAGTCT TTGCCAACTC GTGCCTACCT GGATCAGACA 
GTTGTGCCTA TCTTATTACA GGGACTTGCT GTGCTTGCAA AGGAAAGACC ACCAAATCCC 
ATTGAATTTC TAGCATCTTA TCTTTTAAAA AACAAGGCAC AGTTTGAAGA TCGAAACTGA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OHu17211
Clone ID Related Accession (Same CDS sequence) NM_032574.3 , NM_032574.2 , NM_001321209.1 , NM_001321209.2
Accession Version NM_001321209.1 Documents for ORF clone product in default vector
Sequence Information ORF Nucleotide Sequence (Length: 300bp)
Protein sequence
SNP
Vector pcDNA3.1-C-(k)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ™ Seamless cloning technology
Insert Structure linear
Update Date 2017-10-03
Organism Homo sapiens(human)
Product protein dpy-30 homolog isoform 1
Comment Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from BQ276899.1, AL121655.1, BC015970.1 and BM505380.1. On Mar 18, 2016 this sequence version replaced XM_006712119.2. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BQ276899.1, SRR1163658.131531.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2467144 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end. 

1
61
121
181
241
ATGGAGCCAG AGCAGATGCT GGAGGGACAA ACGCAGGTTG CAGAAAATCC TCACTCTGAG 
TACGGTCTCA CAGACAACGT TGAGAGAATA GTAGAAAATG AGAAGATTAA TGCAGAAAAG 
TCATCAAAGC AGAAGGTAGA TCTCCAGTCT TTGCCAACTC GTGCCTACCT GGATCAGACA 
GTTGTGCCTA TCTTATTACA GGGACTTGCT GTGCTTGCAA AGGAAAGACC ACCAAATCCC 
ATTGAATTTC TAGCATCTTA TCTTTTAAAA AACAAGGCAC AGTTTGAAGA TCGAAACTGA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq NP_001308138.1
CDS140..439
Translation

Target ORF information:

RefSeq Version NM_001321209.1
Organism Homo sapiens(human)
Definition Homo sapiens dpy-30, histone methyltransferase complex regulatory subunit (DPY30), transcript variant 2, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
 NM_001321209.1

ORF Insert Sequence:

1
61
121
181
241
ATGGAGCCAG AGCAGATGCT GGAGGGACAA ACGCAGGTTG CAGAAAATCC TCACTCTGAG 
TACGGTCTCA CAGACAACGT TGAGAGAATA GTAGAAAATG AGAAGATTAA TGCAGAAAAG 
TCATCAAAGC AGAAGGTAGA TCTCCAGTCT TTGCCAACTC GTGCCTACCT GGATCAGACA 
GTTGTGCCTA TCTTATTACA GGGACTTGCT GTGCTTGCAA AGGAAAGACC ACCAAATCCC 
ATTGAATTTC TAGCATCTTA TCTTTTAAAA AACAAGGCAC AGTTTGAAGA TCGAAACTGA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OHu17211
Clone ID Related Accession (Same CDS sequence) NM_032574.3 , NM_032574.2 , NM_001321209.1 , NM_001321209.2
Accession Version NM_001321209.2 Latest version! Documents for ORF clone product in default vector
Sequence Information ORF Nucleotide Sequence (Length: 300bp)
Protein sequence
SNP
Vector pcDNA3.1-C-(k)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ™ Seamless cloning technology
Insert Structure linear
Update Date 2019-07-15
Organism Homo sapiens(human)
Product protein dpy-30 homolog isoform 1
Comment Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from BQ276899.1, BC015970.1 and BM505380.1. On Nov 22, 2018 this sequence version replaced NM_001321209.1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR5189652.186655.1, SRR5189652.190175.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2467144 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000342166.10/ ENSP00000345837.5 RefSeq Select criteria :: based on conservation, expression ##RefSeq-Attributes-END## COMPLETENESS: full length. 

1
61
121
181
241
ATGGAGCCAG AGCAGATGCT GGAGGGACAA ACGCAGGTTG CAGAAAATCC TCACTCTGAG 
TACGGTCTCA CAGACAACGT TGAGAGAATA GTAGAAAATG AGAAGATTAA TGCAGAAAAG 
TCATCAAAGC AGAAGGTAGA TCTCCAGTCT TTGCCAACTC GTGCCTACCT GGATCAGACA 
GTTGTGCCTA TCTTATTACA GGGACTTGCT GTGCTTGCAA AGGAAAGACC ACCAAATCCC 
ATTGAATTTC TAGCATCTTA TCTTTTAAAA AACAAGGCAC AGTTTGAAGA TCGAAACTGA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq NP_001308138.1
CDS110..409
Translation

Target ORF information:

RefSeq Version NM_001321209.2
Organism Homo sapiens(human)
Definition Homo sapiens dpy-30 histone methyltransferase complex regulatory subunit (DPY30), transcript variant 2, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
 NM_001321209.2

ORF Insert Sequence:

1
61
121
181
241
ATGGAGCCAG AGCAGATGCT GGAGGGACAA ACGCAGGTTG CAGAAAATCC TCACTCTGAG 
TACGGTCTCA CAGACAACGT TGAGAGAATA GTAGAAAATG AGAAGATTAA TGCAGAAAAG 
TCATCAAAGC AGAAGGTAGA TCTCCAGTCT TTGCCAACTC GTGCCTACCT GGATCAGACA 
GTTGTGCCTA TCTTATTACA GGGACTTGCT GTGCTTGCAA AGGAAAGACC ACCAAATCCC 
ATTGAATTTC TAGCATCTTA TCTTTTAAAA AACAAGGCAC AGTTTGAAGA TCGAAACTGA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OHu102045
Clone ID Related Accession (Same CDS sequence) NM_001321210.1 , NM_001321210.2
Accession Version NM_001321210.1 Documents for ORF clone product in default vector
Sequence Information ORF Nucleotide Sequence (Length: 231bp)
Protein sequence
SNP
Vector pcDNA3.1-C-(k)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ™ Seamless cloning technology
Insert Structure linear
Update Date 2019-03-11
Organism Homo sapiens(human)
Product protein dpy-30 homolog isoform 2
Comment Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from BQ276899.1, AL121655.1, BG940527.1 and BG187724.1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1163658.534851.1, BG940527.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2148093, SAMEA2162946 [ECO:0000348] ##Evidence-Data-END## 

1
61
121
181
ATGGAGCCAG AGCAGATGCT GGAGGGACAA ACGCAGGTTG CAGAAAATCC TCACTCTGAG 
TACGGTCTCA CAGACAACGT TGAGAGAATA GTAGAAAATG AGAAGATTAA TGCAGAAAAG 
TCATCAAAGC AGAAGGTAGA TCTCCAGTCT TTGCCAACTC GTGCCTACCT GGATCAGACA 
GTTGTGCCTA TCTTATTACA GGGACTTGCT GTGCTTGCAA AGGAAAGATG A

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq NP_001308139.1
CDS140..370
Translation

Target ORF information:

RefSeq Version NM_001321210.1
Organism Homo sapiens(human)
Definition Homo sapiens dpy-30 histone methyltransferase complex regulatory subunit (DPY30), transcript variant 3, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
 NM_001321210.1

ORF Insert Sequence:

1
61
121
181
ATGGAGCCAG AGCAGATGCT GGAGGGACAA ACGCAGGTTG CAGAAAATCC TCACTCTGAG 
TACGGTCTCA CAGACAACGT TGAGAGAATA GTAGAAAATG AGAAGATTAA TGCAGAAAAG 
TCATCAAAGC AGAAGGTAGA TCTCCAGTCT TTGCCAACTC GTGCCTACCT GGATCAGACA 
GTTGTGCCTA TCTTATTACA GGGACTTGCT GTGCTTGCAA AGGAAAGATG A

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OHu102045
Clone ID Related Accession (Same CDS sequence) NM_001321210.1 , NM_001321210.2
Accession Version NM_001321210.2 Latest version! Documents for ORF clone product in default vector
Sequence Information ORF Nucleotide Sequence (Length: 231bp)
Protein sequence
SNP
Vector pcDNA3.1-C-(k)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ™ Seamless cloning technology
Insert Structure linear
Update Date 2019-07-15
Organism Homo sapiens(human)
Product protein dpy-30 homolog isoform 2
Comment Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from BQ276899.1, BG940527.1, BG187724.1 and AL121655.1. On May 31, 2019 this sequence version replaced NM_001321210.1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1163658.534851.1, SRR1163658.275040.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2148093, SAMEA2162946 [ECO:0000348] ##Evidence-Data-END## 

1
61
121
181
ATGGAGCCAG AGCAGATGCT GGAGGGACAA ACGCAGGTTG CAGAAAATCC TCACTCTGAG 
TACGGTCTCA CAGACAACGT TGAGAGAATA GTAGAAAATG AGAAGATTAA TGCAGAAAAG 
TCATCAAAGC AGAAGGTAGA TCTCCAGTCT TTGCCAACTC GTGCCTACCT GGATCAGACA 
GTTGTGCCTA TCTTATTACA GGGACTTGCT GTGCTTGCAA AGGAAAGATG A

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq NP_001308139.1
CDS110..340
Translation

Target ORF information:

RefSeq Version NM_001321210.2
Organism Homo sapiens(human)
Definition Homo sapiens dpy-30 histone methyltransferase complex regulatory subunit (DPY30), transcript variant 3, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
 NM_001321210.2

ORF Insert Sequence:

1
61
121
181
ATGGAGCCAG AGCAGATGCT GGAGGGACAA ACGCAGGTTG CAGAAAATCC TCACTCTGAG 
TACGGTCTCA CAGACAACGT TGAGAGAATA GTAGAAAATG AGAAGATTAA TGCAGAAAAG 
TCATCAAAGC AGAAGGTAGA TCTCCAGTCT TTGCCAACTC GTGCCTACCT GGATCAGACA 
GTTGTGCCTA TCTTATTACA GGGACTTGCT GTGCTTGCAA AGGAAAGATG A

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OHu35634
Clone ID Related Accession (Same CDS sequence) XM_006712117.4 , XM_006712117.3
Accession Version XM_006712117.4 Latest version! Documents for ORF clone product in default vector
Sequence Information ORF Nucleotide Sequence (Length: 363bp)
Protein sequence
SNP
Vector pcDNA3.1-C-(k)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ™ Seamless cloning technology
Insert Structure linear
Update Date 2019-12-05
Organism Homo sapiens(human)
Product protein dpy-30 homolog isoform X2
Comment Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000002.12) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Mar 26, 2018 this sequence version replaced XM_006712117.3. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## 

1
61
121
181
241
301
361
ATGGAGCCAG AGCAGATGCT GGAGGGACAA ACGCAGGTTG CAGAAAATCC TCACTCTGAG 
TACGGTCTCA CAGACAACGT TGAGAGAATA GTAGAAAATG AGAAGATTAA TGCAGAAAAG 
TCATCAAAGC AGAAGGTAGA TCTCCAGTCT TTGCCAACTC GTGCCTACCT GGATCAGACA 
GTTGTGCCTA TCTTATTACA GGGACTTGCT GTGCTTGCAA AGGAAAGAGT TTTACAACAG 
AGAGAAAATA CAGCAGTCAA GTATAATTTA AAAAATTCAG CCAATTTTTC TCAGCATTGT 
TTCTGGACCT TTCTGAGGGT GGGATCTGGG CATCTTCAAT GGCTTAACAA GTATCACAGG 
TGA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq XP_006712180.1
CDS145..507
Translation

Target ORF information:

RefSeq Version XM_006712117.4
Organism Homo sapiens(human)
Definition Homo sapiens dpy-30 histone methyltransferase complex regulatory subunit (DPY30), transcript variant X3, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
 XM_006712117.4

ORF Insert Sequence:

1
61
121
181
241
301
361
ATGGAGCCAG AGCAGATGCT GGAGGGACAA ACGCAGGTTG CAGAAAATCC TCACTCTGAG 
TACGGTCTCA CAGACAACGT TGAGAGAATA GTAGAAAATG AGAAGATTAA TGCAGAAAAG 
TCATCAAAGC AGAAGGTAGA TCTCCAGTCT TTGCCAACTC GTGCCTACCT GGATCAGACA 
GTTGTGCCTA TCTTATTACA GGGACTTGCT GTGCTTGCAA AGGAAAGAGT TTTACAACAG 
AGAGAAAATA CAGCAGTCAA GTATAATTTA AAAAATTCAG CCAATTTTTC TCAGCATTGT 
TTCTGGACCT TTCTGAGGGT GGGATCTGGG CATCTTCAAT GGCTTAACAA GTATCACAGG 
TGA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OHu35634
Clone ID Related Accession (Same CDS sequence) XM_006712117.4 , XM_006712117.3
Accession Version XM_006712117.3 Documents for ORF clone product in default vector
Sequence Information ORF Nucleotide Sequence (Length: 363bp)
Protein sequence
SNP
Vector pcDNA3.1-C-(k)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ™ Seamless cloning technology
Insert Structure linear
Update Date 2016-06-05
Organism Homo sapiens(human)
Product protein dpy-30 homolog isoform X2
Comment Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000002.12) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 6, 2016 this sequence version replaced XM_006712117.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Homo sapiens Annotation Release 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## 

1
61
121
181
241
301
361
ATGGAGCCAG AGCAGATGCT GGAGGGACAA ACGCAGGTTG CAGAAAATCC TCACTCTGAG 
TACGGTCTCA CAGACAACGT TGAGAGAATA GTAGAAAATG AGAAGATTAA TGCAGAAAAG 
TCATCAAAGC AGAAGGTAGA TCTCCAGTCT TTGCCAACTC GTGCCTACCT GGATCAGACA 
GTTGTGCCTA TCTTATTACA GGGACTTGCT GTGCTTGCAA AGGAAAGAGT TTTACAACAG 
AGAGAAAATA CAGCAGTCAA GTATAATTTA AAAAATTCAG CCAATTTTTC TCAGCATTGT 
TTCTGGACCT TTCTGAGGGT GGGATCTGGG CATCTTCAAT GGCTTAACAA GTATCACAGG 
TGA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq XP_006712180.1
CDS145..507
Translation

Target ORF information:

RefSeq Version XM_006712117.3
Organism Homo sapiens(human)
Definition Homo sapiens dpy-30, histone methyltransferase complex regulatory subunit (DPY30), transcript variant X3, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
 XM_006712117.3

ORF Insert Sequence:

1
61
121
181
241
301
361
ATGGAGCCAG AGCAGATGCT GGAGGGACAA ACGCAGGTTG CAGAAAATCC TCACTCTGAG 
TACGGTCTCA CAGACAACGT TGAGAGAATA GTAGAAAATG AGAAGATTAA TGCAGAAAAG 
TCATCAAAGC AGAAGGTAGA TCTCCAGTCT TTGCCAACTC GTGCCTACCT GGATCAGACA 
GTTGTGCCTA TCTTATTACA GGGACTTGCT GTGCTTGCAA AGGAAAGAGT TTTACAACAG 
AGAGAAAATA CAGCAGTCAA GTATAATTTA AAAAATTCAG CCAATTTTTC TCAGCATTGT 
TTCTGGACCT TTCTGAGGGT GGGATCTGGG CATCTTCAAT GGCTTAACAA GTATCACAGG 
TGA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OHu35635
Clone ID Related Accession (Same CDS sequence) XM_017005111.1 , XM_011533133.2 , XM_006712118.3
Accession Version XM_017005111.1 Latest version! Documents for ORF clone product in default vector
Sequence Information ORF Nucleotide Sequence (Length: 363bp)
Protein sequence
SNP
Vector pcDNA3.1-C-(k)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ™ Seamless cloning technology
Insert Structure linear
Update Date 2019-12-05
Organism Homo sapiens(human)
Product protein dpy-30 homolog isoform X1
Comment Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000002.12) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## 

1
61
121
181
241
301
361
ATGGAGCCAG AGCAGATGCT GGAGGGACAA ACGCAGGTTG CAGAAAATCC TCACTCTGAG 
TACGGTCTCA CAGACAACGT TGAGAGAATA GTAGAAAATG AGAAGATTAA TGCAGAAAAG 
TCATCAAAGC AGAAGGTAGA TCTCCAGTCT TTGCCAACTC GTGCCTACCT GGATCAGACA 
GTTGTGCCTA TCTTATTACA GGGACTTGCT GTGCTTGCAA AGGAAAGAGT TTTACAACAG 
AGAGAAAATA CAGCAGTCAA GTATAATTTA AAAAATTCAG CCAATTTTTC TCAGCATTGT 
TTCTGGACCT TTCTGAGGGT GGGATCTGGG CATCTTCAAT GGCTTAACAA GTATCACAGA 
TGA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq XP_016860600.1
CDS145..507
Translation

Target ORF information:

RefSeq Version XM_017005111.1
Organism Homo sapiens(human)
Definition Homo sapiens dpy-30 histone methyltransferase complex regulatory subunit (DPY30), transcript variant X2, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
 XM_017005111.1

ORF Insert Sequence:

1
61
121
181
241
301
361
ATGGAGCCAG AGCAGATGCT GGAGGGACAA ACGCAGGTTG CAGAAAATCC TCACTCTGAG 
TACGGTCTCA CAGACAACGT TGAGAGAATA GTAGAAAATG AGAAGATTAA TGCAGAAAAG 
TCATCAAAGC AGAAGGTAGA TCTCCAGTCT TTGCCAACTC GTGCCTACCT GGATCAGACA 
GTTGTGCCTA TCTTATTACA GGGACTTGCT GTGCTTGCAA AGGAAAGAGT TTTACAACAG 
AGAGAAAATA CAGCAGTCAA GTATAATTTA AAAAATTCAG CCAATTTTTC TCAGCATTGT 
TTCTGGACCT TTCTGAGGGT GGGATCTGGG CATCTTCAAT GGCTTAACAA GTATCACAGA 
TGA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OHu35635
Clone ID Related Accession (Same CDS sequence) XM_017005111.1 , XM_011533133.2 , XM_006712118.3
Accession Version XM_011533133.2 Latest version! Documents for ORF clone product in default vector
Sequence Information ORF Nucleotide Sequence (Length: 363bp)
Protein sequence
SNP
Vector pcDNA3.1-C-(k)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ™ Seamless cloning technology
Insert Structure linear
Update Date 2019-12-05
Organism Homo sapiens(human)
Product protein dpy-30 homolog isoform X1
Comment Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000002.12) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 6, 2016 this sequence version replaced XM_011533133.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## 

1
61
121
181
241
301
361
ATGGAGCCAG AGCAGATGCT GGAGGGACAA ACGCAGGTTG CAGAAAATCC TCACTCTGAG 
TACGGTCTCA CAGACAACGT TGAGAGAATA GTAGAAAATG AGAAGATTAA TGCAGAAAAG 
TCATCAAAGC AGAAGGTAGA TCTCCAGTCT TTGCCAACTC GTGCCTACCT GGATCAGACA 
GTTGTGCCTA TCTTATTACA GGGACTTGCT GTGCTTGCAA AGGAAAGAGT TTTACAACAG 
AGAGAAAATA CAGCAGTCAA GTATAATTTA AAAAATTCAG CCAATTTTTC TCAGCATTGT 
TTCTGGACCT TTCTGAGGGT GGGATCTGGG CATCTTCAAT GGCTTAACAA GTATCACAGA 
TGA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq XP_011531435.1
CDS213..575
Translation

Target ORF information:

RefSeq Version XM_011533133.2
Organism Homo sapiens(human)
Definition Homo sapiens dpy-30 histone methyltransferase complex regulatory subunit (DPY30), transcript variant X4, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
 XM_011533133.2

ORF Insert Sequence:

1
61
121
181
241
301
361
ATGGAGCCAG AGCAGATGCT GGAGGGACAA ACGCAGGTTG CAGAAAATCC TCACTCTGAG 
TACGGTCTCA CAGACAACGT TGAGAGAATA GTAGAAAATG AGAAGATTAA TGCAGAAAAG 
TCATCAAAGC AGAAGGTAGA TCTCCAGTCT TTGCCAACTC GTGCCTACCT GGATCAGACA 
GTTGTGCCTA TCTTATTACA GGGACTTGCT GTGCTTGCAA AGGAAAGAGT TTTACAACAG 
AGAGAAAATA CAGCAGTCAA GTATAATTTA AAAAATTCAG CCAATTTTTC TCAGCATTGT 
TTCTGGACCT TTCTGAGGGT GGGATCTGGG CATCTTCAAT GGCTTAACAA GTATCACAGA 
TGA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OHu35635
Clone ID Related Accession (Same CDS sequence) XM_017005111.1 , XM_011533133.2 , XM_006712118.3
Accession Version XM_006712118.3 Latest version! Documents for ORF clone product in default vector
Sequence Information ORF Nucleotide Sequence (Length: 363bp)
Protein sequence
SNP
Vector pcDNA3.1-C-(k)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ™ Seamless cloning technology
Insert Structure linear
Update Date 2019-12-05
Organism Homo sapiens(human)
Product protein dpy-30 homolog isoform X1
Comment Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000002.12) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 6, 2016 this sequence version replaced XM_006712118.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## 

1
61
121
181
241
301
361
ATGGAGCCAG AGCAGATGCT GGAGGGACAA ACGCAGGTTG CAGAAAATCC TCACTCTGAG 
TACGGTCTCA CAGACAACGT TGAGAGAATA GTAGAAAATG AGAAGATTAA TGCAGAAAAG 
TCATCAAAGC AGAAGGTAGA TCTCCAGTCT TTGCCAACTC GTGCCTACCT GGATCAGACA 
GTTGTGCCTA TCTTATTACA GGGACTTGCT GTGCTTGCAA AGGAAAGAGT TTTACAACAG 
AGAGAAAATA CAGCAGTCAA GTATAATTTA AAAAATTCAG CCAATTTTTC TCAGCATTGT 
TTCTGGACCT TTCTGAGGGT GGGATCTGGG CATCTTCAAT GGCTTAACAA GTATCACAGA 
TGA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq XP_006712181.1
CDS145..507
Translation

Target ORF information:

RefSeq Version XM_006712118.3
Organism Homo sapiens(human)
Definition Homo sapiens dpy-30 histone methyltransferase complex regulatory subunit (DPY30), transcript variant X1, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
 XM_006712118.3

ORF Insert Sequence:

1
61
121
181
241
301
361
ATGGAGCCAG AGCAGATGCT GGAGGGACAA ACGCAGGTTG CAGAAAATCC TCACTCTGAG 
TACGGTCTCA CAGACAACGT TGAGAGAATA GTAGAAAATG AGAAGATTAA TGCAGAAAAG 
TCATCAAAGC AGAAGGTAGA TCTCCAGTCT TTGCCAACTC GTGCCTACCT GGATCAGACA 
GTTGTGCCTA TCTTATTACA GGGACTTGCT GTGCTTGCAA AGGAAAGAGT TTTACAACAG 
AGAGAAAATA CAGCAGTCAA GTATAATTTA AAAAATTCAG CCAATTTTTC TCAGCATTGT 
TTCTGGACCT TTCTGAGGGT GGGATCTGGG CATCTTCAAT GGCTTAACAA GTATCACAGA 
TGA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

PubMed

book

PKA-binding domain of AKAP8 is essential for direct interaction with DPY30 protein.
The FEBS journal(2017 Dec)
Bieluszewska A,Weglewska M,Bieluszewski T,Lesniewicz K,Poreba E


book

Physical Interactions and Functional Coordination between the Core Subunits of Set1/Mll Complexes and the Reprogramming Factors.
PloS one10(12)e0145336(2015)
Yang Z,Augustin J,Hu J,Jiang H