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IKBKG cDNA ORF clone, Homo sapiens(Human)

Gene Symbol IKBKG
Entrez Gene ID 8517
Full Name inhibitor of nuclear factor kappa B kinase subunit gamma
Synonyms AMCBX1,FIP-3,FIP3,Fip3p,IKK-gamma,IKKAP1,IKKG,IMD33,IP,IP1,IP2,IPD2,NEMO,ZC2HC9
General protein information
Preferred Names

inhibitor of nuclear factor kappa B kinase subunit gamma

Names

NF-kappa-B essential modulator
I-kappa-B kinase subunit gamma
NF-kappa-B essential modifier
ikB kinase subunit gamma
ikB kinase-associated protein 1
incontinentia pigmenti
inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma

Gene Type protein-coding
Organism Homo sapiens(Human)
Genome

X

Xq28

Summary This gene encodes the regulatory subunit of the inhibitor of kappaB kinase (IKK) complex, which activates NF-kappaB resulting in activation of genes involved in inflammation, immunity, cell survival, and other pathways. Mutations in this gene result in incontinentia pigmenti, hypohidrotic ectodermal dysplasia, and several other types of immunodeficiencies. A pseudogene highly similar to this locus is located in an adjacent region of the X chromosome. [provided by RefSeq, Mar 2016].
Disorder MIM:

300248

Disorder Html: Incontinentia pigmenti, type II, 308300 (3); Ectodermal dysplasia,

mRNA and Protein(s)

mRNA Protein Name
NM_001321396.1 NP_001308325.1 NF-kappa-B essential modulator isoform a
XM_011531204.1 XP_011529506.1 NF-kappa-B essential modulator isoform X1
NM_001321397.1 NP_001308326.1 NF-kappa-B essential modulator isoform d
NM_003639.4 NP_003630.1 NF-kappa-B essential modulator isoform a
NM_001099856.4 NP_001093326.2 NF-kappa-B essential modulator isoform b
NM_001099857.2 NP_001093327.1 NF-kappa-B essential modulator isoform a
XM_011531205.1 XP_011529507.1 NF-kappa-B essential modulator isoform X1
NM_001145255.2 NP_001138727.1 NF-kappa-B essential modulator isoform c



Pan troglodytes (chimpanzee) LOC100610002 XP_003317847.1
Mus musculus (house mouse) Ikbkg NP_001154894.1
Rattus norvegicus (Norway rat) Ikbkg NP_954534.1
Danio rerio (zebrafish) ikbkg NP_001014366.1
Xenopus tropicalis (tropical clawed frog) ikbkg NP_001120221.1
Canis lupus familiaris (dog) IKBKG XP_005642095.1
Bos taurus (cattle) IKBKG XP_005227781.1
Macaca mulatta (rhesus monkey) IKBKG XP_002806492.1
Homo sapiens (human) IKBKG NP_001093326.2


Related articles in PubMed

Targeting Non-proteolytic Protein Ubiquitination for the Treatment of Diffuse Large B Cell Lymphoma.
Yang Y, Kelly P, Shaffer AL 3rd, Schmitz R, Yoo HM, Liu X, Huang DW, Webster D, Young RM, Nakagawa M, Ceribelli M, Wright GW, Yang Y, Zhao H, Yu X, Xu W, Chan WC, Jaffe ES, Gascoyne RD, Campo E, Rosenwald A, Ott G, Delabie J, Rimsza L, Staudt LM
Cancer cell29(4)494-507(2016 Apr)

Distinct Activation Mechanisms of NF-κB Regulator Inhibitor of NF-κB Kinase (IKK) by Isoforms of the Cell Death Regulator Cellular FLICE-like Inhibitory Protein (cFLIP).
Baratchian M, Davis CA, Shimizu A, Escors D, Bagnéris C, Barrett T, Collins MK
The Journal of biological chemistry291(14)7608-20(2016 Apr)

Recruitment of A20 by the C-terminal domain of NEMO suppresses NF-κB activation and autoinflammatory disease.
Zilberman-Rudenko J, Shawver LM, Wessel AW, Luo Y, Pelletier M, Tsai WL, Lee Y, Vonortas S, Cheng L, Ashwell JD, Orange JS, Siegel RM, Hanson EP
Proceedings of the National Academy of Sciences of the United States of America113(6)1612-7(2016 Feb)

Autoubiquitination of TRIM26 links TBK1 to NEMO in RLR-mediated innate antiviral immune response.
Ran Y, Zhang J, Liu LL, Pan ZY, Nie Y, Zhang HY, Wang YY
Journal of molecular cell biology8(1)31-43(2016 Feb)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Molluscum contagiosum virus MC005 inhibited NF-kappaB proximal to the IkappaB kinase (IKK) complex, and unbiased affinity purification revealed that MC005 interacts with the IKK subunit NEMO (NF-kappaB essential modulator).
Title: Molluscum Contagiosum Virus Protein MC005 Inhibits NF-κB Activation by Targeting NEMO-Regulated IκB Kinase Activation.

These data suggest that molluscum contagiosum virus MC159 competitively binds to NEMO to prevent cIAP1-induced NEMO polyubiquitination.
Title: Molluscum Contagiosum Virus MC159 Abrogates cIAP1-NEMO Interactions and Inhibits NEMO Polyubiquitination.

FADD, as well as NEMO, is a substrate for LUBAC ubiquitin ligase (E3) complex, composed of the HOIP, HOIL-1L, and SHARPIN subunits.
Title: Decreased linear ubiquitination of NEMO and FADD on apoptosis with caspase-mediated cleavage of HOIP.

Consistent with experimental evidence, the zinc ion is essential for mechanical stabilization of the functional, folded conformation of NEMO.
Title: Binding Site Configurations Probe the Structure and Dynamics of the Zinc Finger of NEMO (NF-κB Essential Modulator).

High IKBKG expression is associated with multiple myeloma.
Title: Genomic studies of multiple myeloma reveal an association between X chromosome alterations and genomic profile complexity.

The following IKBKG gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the IKBKG cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

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***CloneID RefSeq Accession Definition **Vector *Turnaround time Price (USD) Select
OHu27518
NM_001099857.2
Latest version!
Homo sapiens inhibitor of nuclear factor kappa B kinase subunit gamma (IKBKG), transcript variant 1, mRNA. pcDNA3.1+/C-(K)DYK or customized vector
in pcDNA3.1+/C-(K)DYK
$159.50-$223.30
$319.00
OHu27518
NM_003639.4
Latest version!
Homo sapiens inhibitor of nuclear factor kappa B kinase subunit gamma (IKBKG), transcript variant 3, mRNA. pcDNA3.1+/C-(K)DYK or customized vector
in pcDNA3.1+/C-(K)DYK
$159.50-$223.30
$319.00
OHu27518
NM_001321396.1
Latest version!
Homo sapiens inhibitor of nuclear factor kappa B kinase subunit gamma (IKBKG), transcript variant 5, mRNA. pcDNA3.1+/C-(K)DYK or customized vector
in pcDNA3.1+/C-(K)DYK
$159.50-$223.30
$319.00
OHu27518
XM_011531204.1
Latest version!
Homo sapiens inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma (IKBKG), transcript variant X4, mRNA. pcDNA3.1+/C-(K)DYK or customized vector
in pcDNA3.1+/C-(K)DYK
$159.50-$223.30
$319.00
OHu27518
XM_011531205.1
Latest version!
Homo sapiens inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma (IKBKG), transcript variant X5, mRNA. pcDNA3.1+/C-(K)DYK or customized vector
in pcDNA3.1+/C-(K)DYK
$159.50-$223.30
$319.00
OHu16932 NM_001099856.4
Latest version!
Homo sapiens inhibitor of nuclear factor kappa B kinase subunit gamma (IKBKG), transcript variant 2, mRNA. pcDNA3.1+/C-(K)DYK or customized vector 7-9 $223.30
$319.00
OHu27490 NM_001145255.2
Latest version!
Homo sapiens inhibitor of nuclear factor kappa B kinase subunit gamma (IKBKG), transcript variant 4, mRNA. pcDNA3.1+/C-(K)DYK or customized vector 7-9 $216.30
$309.00
OHu54458 NM_001321397.1
Latest version!
Homo sapiens inhibitor of nuclear factor kappa B kinase subunit gamma (IKBKG), transcript variant 6, mRNA. pcDNA3.1+/C-(K)DYK or customized vector 7-9 $223.30
$319.00

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.


CloneID OHu27518
Clone ID Related Accession (Same CDS sequence) NM_001321396.1 , XM_011531204.1 , NM_003639.4 , NM_001099857.2 , XM_011531205.1
Accession Version NM_001321396.1 Latest version! Documents for ORF clone product in dufault vector
Sequence Information ORF Nucleotide Sequence (Length: 1260bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags COA
ORF Insert Method CloneEZ® Seamless cloning technology
Insert Structure linear
Update Date 2017-04-09
Organism Homo sapiens(Human)
Product NF-kappa-B essential modulator isoform a
Comment REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from BM473416.1, AF074382.1, AC244090.3 and AF062089.1. Transcript Variant: Variants 1, 3 and 5 encode the same isoform (a). Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AF074382.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2144333, SAMEA2145743 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
ATGAATAGGC ACCTCTGGAA GAGCCAACTG TGTGAGATGG TGCAGCCCAG TGGTGGCCCG 
GCAGCAGATC AGGACGTACT GGGCGAAGAG TCTCCTCTGG GGAAGCCAGC CATGCTGCAC
CTGCCTTCAG AACAGGGCGC TCCTGAGACC CTCCAGCGCT GCCTGGAGGA GAATCAAGAG
CTCCGAGATG CCATCCGGCA GAGCAACCAG ATTCTGCGGG AGCGCTGCGA GGAGCTTCTG
CATTTCCAAG CCAGCCAGAG GGAGGAGAAG GAGTTCCTCA TGTGCAAGTT CCAGGAGGCC
AGGAAACTGG TGGAGAGACT CGGCCTGGAG AAGCTCGATC TGAAGAGGCA GAAGGAGCAG
GCTCTGCGGG AGGTGGAGCA CCTGAAGAGA TGCCAGCAGC AGATGGCTGA GGACAAGGCC
TCTGTGAAAG CCCAGGTGAC GTCCTTGCTC GGGGAGCTGC AGGAGAGCCA GAGTCGCTTG
GAGGCTGCCA CTAAGGAATG CCAGGCTCTG GAGGGTCGGG CCCGGGCGGC CAGCGAGCAG
GCGCGGCAGC TGGAGAGTGA GCGCGAGGCG CTGCAGCAGC AGCACAGCGT GCAGGTGGAC
CAGCTGCGCA TGCAGGGCCA GAGCGTGGAG GCCGCGCTCC GCATGGAGCG CCAGGCCGCC
TCGGAGGAGA AGAGGAAGCT GGCCCAGTTG CAGGTGGCCT ATCACCAGCT CTTCCAAGAA
TACGACAACC ACATCAAGAG CAGCGTGGTG GGCAGTGAGC GGAAGCGAGG AATGCAGCTG
GAAGATCTCA AACAGCAGCT CCAGCAGGCC GAGGAGGCCC TGGTGGCCAA ACAGGAGGTG
ATCGATAAGC TGAAGGAGGA GGCCGAGCAG CACAAGATTG TGATGGAGAC CGTTCCGGTG
CTGAAGGCCC AGGCGGATAT CTACAAGGCG GACTTCCAGG CTGAGAGGCA GGCCCGGGAG
AAGCTGGCCG AGAAGAAGGA GCTCCTGCAG GAGCAGCTGG AGCAGCTGCA GAGGGAGTAC
AGCAAACTGA AGGCCAGCTG TCAGGAGTCG GCCAGGATCG AGGACATGAG GAAGCGGCAT
GTCGAGGTCT CCCAGGCCCC CTTGCCCCCC GCCCCTGCCT ACCTCTCCTC TCCCCTGGCC
CTGCCCAGCC AGAGGAGGAG CCCCCCCGAG GAGCCACCTG ACTTCTGCTG TCCCAAGTGC
CAGTATCAGG CCCCTGATAT GGACACCCTG CAGATACATG TCATGGAGTG CATTGAGTAG

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq NP_001308325.1
CDS164..1423
Misc Feature(1)116..118
Misc Feature(2)254..256
Misc Feature(3)290..292
Misc Feature(4)293..496
Misc Feature(5)293..496
Misc Feature(6)365..367
Misc Feature(7)416..418
Misc Feature(8)611..934
Misc Feature(9)887..1213
Misc Feature(10)899..1258
Misc Feature(11)914..1420
Misc Feature(12)938..1195
Misc Feature(13)order(938..943,950..955,959..964,971..973,980..985,992..997,1001..1006,1013..1015,1025..1027,1034..1036,1055..1057,1064..1066,1073..1078,1085..1087,1094..1099,1106..1111,1115..1120,1127..1132,1139..1141,1151..1153,1160..1162,1172..1174,1181..1183)
Misc Feature(14)order(1049..1051,1061..1066,1070..1075,1082..1090,1094..1099,1103..1111,1118..1123,1130..1135,1142..1144)
Misc Feature(15)1127..1192
Misc Feature(16)1289..1291
Misc Feature(17)1307..1420
Misc Feature(18)1322..1324
Exon (1)1..148
Exon (2)149..350
Exon (3)351..562
Exon (4)563..681
Exon (5)682..834
Exon (6)835..931
Exon (7)932..1075
Exon (8)1076..1218
Exon (9)1219..1280
Exon (10)1281..2008
Translation

Target ORF information:

RefSeq Version NM_001321396.1
Organism Homo sapiens(Human)
Definition Homo sapiens inhibitor of nuclear factor kappa B kinase subunit gamma (IKBKG), transcript variant 5, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
NM_001321396.1

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
ATGAATAGGC ACCTCTGGAA GAGCCAACTG TGTGAGATGG TGCAGCCCAG TGGTGGCCCG 
GCAGCAGATC AGGACGTACT GGGCGAAGAG TCTCCTCTGG GGAAGCCAGC CATGCTGCAC
CTGCCTTCAG AACAGGGCGC TCCTGAGACC CTCCAGCGCT GCCTGGAGGA GAATCAAGAG
CTCCGAGATG CCATCCGGCA GAGCAACCAG ATTCTGCGGG AGCGCTGCGA GGAGCTTCTG
CATTTCCAAG CCAGCCAGAG GGAGGAGAAG GAGTTCCTCA TGTGCAAGTT CCAGGAGGCC
AGGAAACTGG TGGAGAGACT CGGCCTGGAG AAGCTCGATC TGAAGAGGCA GAAGGAGCAG
GCTCTGCGGG AGGTGGAGCA CCTGAAGAGA TGCCAGCAGC AGATGGCTGA GGACAAGGCC
TCTGTGAAAG CCCAGGTGAC GTCCTTGCTC GGGGAGCTGC AGGAGAGCCA GAGTCGCTTG
GAGGCTGCCA CTAAGGAATG CCAGGCTCTG GAGGGTCGGG CCCGGGCGGC CAGCGAGCAG
GCGCGGCAGC TGGAGAGTGA GCGCGAGGCG CTGCAGCAGC AGCACAGCGT GCAGGTGGAC
CAGCTGCGCA TGCAGGGCCA GAGCGTGGAG GCCGCGCTCC GCATGGAGCG CCAGGCCGCC
TCGGAGGAGA AGAGGAAGCT GGCCCAGTTG CAGGTGGCCT ATCACCAGCT CTTCCAAGAA
TACGACAACC ACATCAAGAG CAGCGTGGTG GGCAGTGAGC GGAAGCGAGG AATGCAGCTG
GAAGATCTCA AACAGCAGCT CCAGCAGGCC GAGGAGGCCC TGGTGGCCAA ACAGGAGGTG
ATCGATAAGC TGAAGGAGGA GGCCGAGCAG CACAAGATTG TGATGGAGAC CGTTCCGGTG
CTGAAGGCCC AGGCGGATAT CTACAAGGCG GACTTCCAGG CTGAGAGGCA GGCCCGGGAG
AAGCTGGCCG AGAAGAAGGA GCTCCTGCAG GAGCAGCTGG AGCAGCTGCA GAGGGAGTAC
AGCAAACTGA AGGCCAGCTG TCAGGAGTCG GCCAGGATCG AGGACATGAG GAAGCGGCAT
GTCGAGGTCT CCCAGGCCCC CTTGCCCCCC GCCCCTGCCT ACCTCTCCTC TCCCCTGGCC
CTGCCCAGCC AGAGGAGGAG CCCCCCCGAG GAGCCACCTG ACTTCTGCTG TCCCAAGTGC
CAGTATCAGG CCCCTGATAT GGACACCCTG CAGATACATG TCATGGAGTG CATTGAGTAG

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OHu27518
Clone ID Related Accession (Same CDS sequence) NM_001321396.1 , XM_011531204.1 , NM_003639.4 , NM_001099857.2 , XM_011531205.1
Accession Version NM_003639.4 Latest version! Documents for ORF clone product in dufault vector
Sequence Information ORF Nucleotide Sequence (Length: 1260bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags COA
ORF Insert Method CloneEZ® Seamless cloning technology
Insert Structure linear
Update Date 2017-04-30
Organism Homo sapiens(Human)
Product NF-kappa-B essential modulator isoform a
Comment REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AF261086.1, BC000299.2 and AF062089.1. On Sep 17, 2013 this sequence version replaced NM_003639.3. Transcript Variant: This variant (3) differs in the 5' UTR compared to variant 1. Variants 1, 3 and 5 encode the same isoform (a). Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AF261086.1, SRR1163655.660637.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1968968 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
ATGAATAGGC ACCTCTGGAA GAGCCAACTG TGTGAGATGG TGCAGCCCAG TGGTGGCCCG 
GCAGCAGATC AGGACGTACT GGGCGAAGAG TCTCCTCTGG GGAAGCCAGC CATGCTGCAC
CTGCCTTCAG AACAGGGCGC TCCTGAGACC CTCCAGCGCT GCCTGGAGGA GAATCAAGAG
CTCCGAGATG CCATCCGGCA GAGCAACCAG ATTCTGCGGG AGCGCTGCGA GGAGCTTCTG
CATTTCCAAG CCAGCCAGAG GGAGGAGAAG GAGTTCCTCA TGTGCAAGTT CCAGGAGGCC
AGGAAACTGG TGGAGAGACT CGGCCTGGAG AAGCTCGATC TGAAGAGGCA GAAGGAGCAG
GCTCTGCGGG AGGTGGAGCA CCTGAAGAGA TGCCAGCAGC AGATGGCTGA GGACAAGGCC
TCTGTGAAAG CCCAGGTGAC GTCCTTGCTC GGGGAGCTGC AGGAGAGCCA GAGTCGCTTG
GAGGCTGCCA CTAAGGAATG CCAGGCTCTG GAGGGTCGGG CCCGGGCGGC CAGCGAGCAG
GCGCGGCAGC TGGAGAGTGA GCGCGAGGCG CTGCAGCAGC AGCACAGCGT GCAGGTGGAC
CAGCTGCGCA TGCAGGGCCA GAGCGTGGAG GCCGCGCTCC GCATGGAGCG CCAGGCCGCC
TCGGAGGAGA AGAGGAAGCT GGCCCAGTTG CAGGTGGCCT ATCACCAGCT CTTCCAAGAA
TACGACAACC ACATCAAGAG CAGCGTGGTG GGCAGTGAGC GGAAGCGAGG AATGCAGCTG
GAAGATCTCA AACAGCAGCT CCAGCAGGCC GAGGAGGCCC TGGTGGCCAA ACAGGAGGTG
ATCGATAAGC TGAAGGAGGA GGCCGAGCAG CACAAGATTG TGATGGAGAC CGTTCCGGTG
CTGAAGGCCC AGGCGGATAT CTACAAGGCG GACTTCCAGG CTGAGAGGCA GGCCCGGGAG
AAGCTGGCCG AGAAGAAGGA GCTCCTGCAG GAGCAGCTGG AGCAGCTGCA GAGGGAGTAC
AGCAAACTGA AGGCCAGCTG TCAGGAGTCG GCCAGGATCG AGGACATGAG GAAGCGGCAT
GTCGAGGTCT CCCAGGCCCC CTTGCCCCCC GCCCCTGCCT ACCTCTCCTC TCCCCTGGCC
CTGCCCAGCC AGAGGAGGAG CCCCCCCGAG GAGCCACCTG ACTTCTGCTG TCCCAAGTGC
CAGTATCAGG CCCCTGATAT GGACACCCTG CAGATACATG TCATGGAGTG CATTGAGTAG

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq NP_003630.1
CDS259..1518
Misc Feature(1)241..243
Misc Feature(2)349..351
Misc Feature(3)349..351
Misc Feature(4)385..387
Misc Feature(5)385..387
Misc Feature(6)388..591
Misc Feature(7)388..591
Misc Feature(8)460..462
Misc Feature(9)511..513
Misc Feature(10)706..1029
Misc Feature(11)982..1308
Misc Feature(12)994..1353
Misc Feature(13)1009..1515
Misc Feature(14)1033..1290
Misc Feature(15)order(1033..1038,1045..1050,1054..1059,1066..1068,1075..1080,1087..1092,1096..1101,1108..1110,1120..1122,1129..1131,1150..1152,1159..1161,1168..1173,1180..1182,1189..1194,1201..1206,1210..1215,1222..1227,1234..1236,1246..1248,1255..1257,1267..1269,1276..1278)
Misc Feature(16)order(1144..1146,1156..1161,1165..1170,1177..1185,1189..1194,1198..1206,1213..1218,1225..1230,1237..1239)
Misc Feature(17)1222..1287
Misc Feature(18)1384..1386
Misc Feature(19)1384..1386
Misc Feature(20)1402..1515
Misc Feature(21)1417..1419
Misc Feature(22)1453..1455
Exon (1)1..243
Exon (2)244..445
Exon (3)446..657
Exon (4)658..776
Exon (5)777..929
Exon (6)930..1026
Exon (7)1027..1170
Exon (8)1171..1313
Exon (9)1314..1375
Exon (10)1376..2103
Translation

Target ORF information:

RefSeq Version NM_003639.4
Organism Homo sapiens(Human)
Definition Homo sapiens inhibitor of nuclear factor kappa B kinase subunit gamma (IKBKG), transcript variant 3, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
NM_003639.4

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
ATGAATAGGC ACCTCTGGAA GAGCCAACTG TGTGAGATGG TGCAGCCCAG TGGTGGCCCG 
GCAGCAGATC AGGACGTACT GGGCGAAGAG TCTCCTCTGG GGAAGCCAGC CATGCTGCAC
CTGCCTTCAG AACAGGGCGC TCCTGAGACC CTCCAGCGCT GCCTGGAGGA GAATCAAGAG
CTCCGAGATG CCATCCGGCA GAGCAACCAG ATTCTGCGGG AGCGCTGCGA GGAGCTTCTG
CATTTCCAAG CCAGCCAGAG GGAGGAGAAG GAGTTCCTCA TGTGCAAGTT CCAGGAGGCC
AGGAAACTGG TGGAGAGACT CGGCCTGGAG AAGCTCGATC TGAAGAGGCA GAAGGAGCAG
GCTCTGCGGG AGGTGGAGCA CCTGAAGAGA TGCCAGCAGC AGATGGCTGA GGACAAGGCC
TCTGTGAAAG CCCAGGTGAC GTCCTTGCTC GGGGAGCTGC AGGAGAGCCA GAGTCGCTTG
GAGGCTGCCA CTAAGGAATG CCAGGCTCTG GAGGGTCGGG CCCGGGCGGC CAGCGAGCAG
GCGCGGCAGC TGGAGAGTGA GCGCGAGGCG CTGCAGCAGC AGCACAGCGT GCAGGTGGAC
CAGCTGCGCA TGCAGGGCCA GAGCGTGGAG GCCGCGCTCC GCATGGAGCG CCAGGCCGCC
TCGGAGGAGA AGAGGAAGCT GGCCCAGTTG CAGGTGGCCT ATCACCAGCT CTTCCAAGAA
TACGACAACC ACATCAAGAG CAGCGTGGTG GGCAGTGAGC GGAAGCGAGG AATGCAGCTG
GAAGATCTCA AACAGCAGCT CCAGCAGGCC GAGGAGGCCC TGGTGGCCAA ACAGGAGGTG
ATCGATAAGC TGAAGGAGGA GGCCGAGCAG CACAAGATTG TGATGGAGAC CGTTCCGGTG
CTGAAGGCCC AGGCGGATAT CTACAAGGCG GACTTCCAGG CTGAGAGGCA GGCCCGGGAG
AAGCTGGCCG AGAAGAAGGA GCTCCTGCAG GAGCAGCTGG AGCAGCTGCA GAGGGAGTAC
AGCAAACTGA AGGCCAGCTG TCAGGAGTCG GCCAGGATCG AGGACATGAG GAAGCGGCAT
GTCGAGGTCT CCCAGGCCCC CTTGCCCCCC GCCCCTGCCT ACCTCTCCTC TCCCCTGGCC
CTGCCCAGCC AGAGGAGGAG CCCCCCCGAG GAGCCACCTG ACTTCTGCTG TCCCAAGTGC
CAGTATCAGG CCCCTGATAT GGACACCCTG CAGATACATG TCATGGAGTG CATTGAGTAG

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OHu27518
Clone ID Related Accession (Same CDS sequence) NM_001321396.1 , XM_011531204.1 , NM_003639.4 , NM_001099857.2 , XM_011531205.1
Accession Version NM_001099857.2 Latest version! Documents for ORF clone product in dufault vector
Sequence Information ORF Nucleotide Sequence (Length: 1260bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags COA
ORF Insert Method CloneEZ® Seamless cloning technology
Insert Structure linear
Update Date 2017-04-09
Organism Homo sapiens(Human)
Product NF-kappa-B essential modulator isoform a
Comment REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AK308366.1, BC050612.2, BC000299.2 and AF062089.1. On Sep 17, 2013 this sequence version replaced NM_001099857.1. Transcript Variant: This variant (1) represents the longest transcript and encodes isoform a. Variants 1, 3 and 5 encode the same isoform. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AF062089.1, BC050612.2 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
ATGAATAGGC ACCTCTGGAA GAGCCAACTG TGTGAGATGG TGCAGCCCAG TGGTGGCCCG 
GCAGCAGATC AGGACGTACT GGGCGAAGAG TCTCCTCTGG GGAAGCCAGC CATGCTGCAC
CTGCCTTCAG AACAGGGCGC TCCTGAGACC CTCCAGCGCT GCCTGGAGGA GAATCAAGAG
CTCCGAGATG CCATCCGGCA GAGCAACCAG ATTCTGCGGG AGCGCTGCGA GGAGCTTCTG
CATTTCCAAG CCAGCCAGAG GGAGGAGAAG GAGTTCCTCA TGTGCAAGTT CCAGGAGGCC
AGGAAACTGG TGGAGAGACT CGGCCTGGAG AAGCTCGATC TGAAGAGGCA GAAGGAGCAG
GCTCTGCGGG AGGTGGAGCA CCTGAAGAGA TGCCAGCAGC AGATGGCTGA GGACAAGGCC
TCTGTGAAAG CCCAGGTGAC GTCCTTGCTC GGGGAGCTGC AGGAGAGCCA GAGTCGCTTG
GAGGCTGCCA CTAAGGAATG CCAGGCTCTG GAGGGTCGGG CCCGGGCGGC CAGCGAGCAG
GCGCGGCAGC TGGAGAGTGA GCGCGAGGCG CTGCAGCAGC AGCACAGCGT GCAGGTGGAC
CAGCTGCGCA TGCAGGGCCA GAGCGTGGAG GCCGCGCTCC GCATGGAGCG CCAGGCCGCC
TCGGAGGAGA AGAGGAAGCT GGCCCAGTTG CAGGTGGCCT ATCACCAGCT CTTCCAAGAA
TACGACAACC ACATCAAGAG CAGCGTGGTG GGCAGTGAGC GGAAGCGAGG AATGCAGCTG
GAAGATCTCA AACAGCAGCT CCAGCAGGCC GAGGAGGCCC TGGTGGCCAA ACAGGAGGTG
ATCGATAAGC TGAAGGAGGA GGCCGAGCAG CACAAGATTG TGATGGAGAC CGTTCCGGTG
CTGAAGGCCC AGGCGGATAT CTACAAGGCG GACTTCCAGG CTGAGAGGCA GGCCCGGGAG
AAGCTGGCCG AGAAGAAGGA GCTCCTGCAG GAGCAGCTGG AGCAGCTGCA GAGGGAGTAC
AGCAAACTGA AGGCCAGCTG TCAGGAGTCG GCCAGGATCG AGGACATGAG GAAGCGGCAT
GTCGAGGTCT CCCAGGCCCC CTTGCCCCCC GCCCCTGCCT ACCTCTCCTC TCCCCTGGCC
CTGCCCAGCC AGAGGAGGAG CCCCCCCGAG GAGCCACCTG ACTTCTGCTG TCCCAAGTGC
CAGTATCAGG CCCCTGATAT GGACACCCTG CAGATACATG TCATGGAGTG CATTGAGTAG

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq NP_001093327.1
CDS415..1674
Misc Feature(1)394..396
Misc Feature(2)505..507
Misc Feature(3)541..543
Misc Feature(4)544..747
Misc Feature(5)544..747
Misc Feature(6)616..618
Misc Feature(7)667..669
Misc Feature(8)862..1185
Misc Feature(9)1138..1464
Misc Feature(10)1150..1509
Misc Feature(11)1165..1671
Misc Feature(12)1189..1446
Misc Feature(13)order(1189..1194,1201..1206,1210..1215,1222..1224,1231..1236,1243..1248,1252..1257,1264..1266,1276..1278,1285..1287,1306..1308,1315..1317,1324..1329,1336..1338,1345..1350,1357..1362,1366..1371,1378..1383,1390..1392,1402..1404,1411..1413,1423..1425,1432..1434)
Misc Feature(14)order(1300..1302,1312..1317,1321..1326,1333..1341,1345..1350,1354..1362,1369..1374,1381..1386,1393..1395)
Misc Feature(15)1378..1443
Misc Feature(16)1540..1542
Misc Feature(17)1558..1671
Misc Feature(18)1573..1575
Exon (1)1..399
Exon (2)400..601
Exon (3)602..813
Exon (4)814..932
Exon (5)933..1085
Exon (6)1086..1182
Exon (7)1183..1326
Exon (8)1327..1469
Exon (9)1470..1531
Exon (10)1532..2259
Translation

Target ORF information:

RefSeq Version NM_001099857.2
Organism Homo sapiens(Human)
Definition Homo sapiens inhibitor of nuclear factor kappa B kinase subunit gamma (IKBKG), transcript variant 1, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
NM_001099857.2

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
ATGAATAGGC ACCTCTGGAA GAGCCAACTG TGTGAGATGG TGCAGCCCAG TGGTGGCCCG 
GCAGCAGATC AGGACGTACT GGGCGAAGAG TCTCCTCTGG GGAAGCCAGC CATGCTGCAC
CTGCCTTCAG AACAGGGCGC TCCTGAGACC CTCCAGCGCT GCCTGGAGGA GAATCAAGAG
CTCCGAGATG CCATCCGGCA GAGCAACCAG ATTCTGCGGG AGCGCTGCGA GGAGCTTCTG
CATTTCCAAG CCAGCCAGAG GGAGGAGAAG GAGTTCCTCA TGTGCAAGTT CCAGGAGGCC
AGGAAACTGG TGGAGAGACT CGGCCTGGAG AAGCTCGATC TGAAGAGGCA GAAGGAGCAG
GCTCTGCGGG AGGTGGAGCA CCTGAAGAGA TGCCAGCAGC AGATGGCTGA GGACAAGGCC
TCTGTGAAAG CCCAGGTGAC GTCCTTGCTC GGGGAGCTGC AGGAGAGCCA GAGTCGCTTG
GAGGCTGCCA CTAAGGAATG CCAGGCTCTG GAGGGTCGGG CCCGGGCGGC CAGCGAGCAG
GCGCGGCAGC TGGAGAGTGA GCGCGAGGCG CTGCAGCAGC AGCACAGCGT GCAGGTGGAC
CAGCTGCGCA TGCAGGGCCA GAGCGTGGAG GCCGCGCTCC GCATGGAGCG CCAGGCCGCC
TCGGAGGAGA AGAGGAAGCT GGCCCAGTTG CAGGTGGCCT ATCACCAGCT CTTCCAAGAA
TACGACAACC ACATCAAGAG CAGCGTGGTG GGCAGTGAGC GGAAGCGAGG AATGCAGCTG
GAAGATCTCA AACAGCAGCT CCAGCAGGCC GAGGAGGCCC TGGTGGCCAA ACAGGAGGTG
ATCGATAAGC TGAAGGAGGA GGCCGAGCAG CACAAGATTG TGATGGAGAC CGTTCCGGTG
CTGAAGGCCC AGGCGGATAT CTACAAGGCG GACTTCCAGG CTGAGAGGCA GGCCCGGGAG
AAGCTGGCCG AGAAGAAGGA GCTCCTGCAG GAGCAGCTGG AGCAGCTGCA GAGGGAGTAC
AGCAAACTGA AGGCCAGCTG TCAGGAGTCG GCCAGGATCG AGGACATGAG GAAGCGGCAT
GTCGAGGTCT CCCAGGCCCC CTTGCCCCCC GCCCCTGCCT ACCTCTCCTC TCCCCTGGCC
CTGCCCAGCC AGAGGAGGAG CCCCCCCGAG GAGCCACCTG ACTTCTGCTG TCCCAAGTGC
CAGTATCAGG CCCCTGATAT GGACACCCTG CAGATACATG TCATGGAGTG CATTGAGTAG

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OHu27518
Clone ID Related Accession (Same CDS sequence) NM_001321396.1 , XM_011531204.1 , NM_003639.4 , NM_001099857.2 , XM_011531205.1
Accession Version XM_011531204.1 Latest version! Documents for ORF clone product in dufault vector
Sequence Information ORF Nucleotide Sequence (Length: 1260bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags COA
ORF Insert Method CloneEZ® Seamless cloning technology
Insert Structure linear
Update Date 2015-03-12
Organism Homo sapiens(Human)
Product NF-kappa-B essential modulator isoform X1
Comment

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
ATGAATAGGC ACCTCTGGAA GAGCCAACTG TGTGAGATGG TGCAGCCCAG TGGTGGCCCG 
GCAGCAGATC AGGACGTACT GGGCGAAGAG TCTCCTCTGG GGAAGCCAGC CATGCTGCAC
CTGCCTTCAG AACAGGGCGC TCCTGAGACC CTCCAGCGCT GCCTGGAGGA GAATCAAGAG
CTCCGAGATG CCATCCGGCA GAGCAACCAG ATTCTGCGGG AGCGCTGCGA GGAGCTTCTG
CATTTCCAAG CCAGCCAGAG GGAGGAGAAG GAGTTCCTCA TGTGCAAGTT CCAGGAGGCC
AGGAAACTGG TGGAGAGACT CGGCCTGGAG AAGCTCGATC TGAAGAGGCA GAAGGAGCAG
GCTCTGCGGG AGGTGGAGCA CCTGAAGAGA TGCCAGCAGC AGATGGCTGA GGACAAGGCC
TCTGTGAAAG CCCAGGTGAC GTCCTTGCTC GGGGAGCTGC AGGAGAGCCA GAGTCGCTTG
GAGGCTGCCA CTAAGGAATG CCAGGCTCTG GAGGGTCGGG CCCGGGCGGC CAGCGAGCAG
GCGCGGCAGC TGGAGAGTGA GCGCGAGGCG CTGCAGCAGC AGCACAGCGT GCAGGTGGAC
CAGCTGCGCA TGCAGGGCCA GAGCGTGGAG GCCGCGCTCC GCATGGAGCG CCAGGCCGCC
TCGGAGGAGA AGAGGAAGCT GGCCCAGTTG CAGGTGGCCT ATCACCAGCT CTTCCAAGAA
TACGACAACC ACATCAAGAG CAGCGTGGTG GGCAGTGAGC GGAAGCGAGG AATGCAGCTG
GAAGATCTCA AACAGCAGCT CCAGCAGGCC GAGGAGGCCC TGGTGGCCAA ACAGGAGGTG
ATCGATAAGC TGAAGGAGGA GGCCGAGCAG CACAAGATTG TGATGGAGAC CGTTCCGGTG
CTGAAGGCCC AGGCGGATAT CTACAAGGCG GACTTCCAGG CTGAGAGGCA GGCCCGGGAG
AAGCTGGCCG AGAAGAAGGA GCTCCTGCAG GAGCAGCTGG AGCAGCTGCA GAGGGAGTAC
AGCAAACTGA AGGCCAGCTG TCAGGAGTCG GCCAGGATCG AGGACATGAG GAAGCGGCAT
GTCGAGGTCT CCCAGGCCCC CTTGCCCCCC GCCCCTGCCT ACCTCTCCTC TCCCCTGGCC
CTGCCCAGCC AGAGGAGGAG CCCCCCCGAG GAGCCACCTG ACTTCTGCTG TCCCAAGTGC
CAGTATCAGG CCCCTGATAT GGACACCCTG CAGATACATG TCATGGAGTG CATTGAGTAG

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq XP_011529506.1
Translation

Target ORF information:

RefSeq Version XM_011531204.1
Organism Homo sapiens(Human)
Definition Homo sapiens inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma (IKBKG), transcript variant X4, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
XM_011531204.1

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
ATGAATAGGC ACCTCTGGAA GAGCCAACTG TGTGAGATGG TGCAGCCCAG TGGTGGCCCG 
GCAGCAGATC AGGACGTACT GGGCGAAGAG TCTCCTCTGG GGAAGCCAGC CATGCTGCAC
CTGCCTTCAG AACAGGGCGC TCCTGAGACC CTCCAGCGCT GCCTGGAGGA GAATCAAGAG
CTCCGAGATG CCATCCGGCA GAGCAACCAG ATTCTGCGGG AGCGCTGCGA GGAGCTTCTG
CATTTCCAAG CCAGCCAGAG GGAGGAGAAG GAGTTCCTCA TGTGCAAGTT CCAGGAGGCC
AGGAAACTGG TGGAGAGACT CGGCCTGGAG AAGCTCGATC TGAAGAGGCA GAAGGAGCAG
GCTCTGCGGG AGGTGGAGCA CCTGAAGAGA TGCCAGCAGC AGATGGCTGA GGACAAGGCC
TCTGTGAAAG CCCAGGTGAC GTCCTTGCTC GGGGAGCTGC AGGAGAGCCA GAGTCGCTTG
GAGGCTGCCA CTAAGGAATG CCAGGCTCTG GAGGGTCGGG CCCGGGCGGC CAGCGAGCAG
GCGCGGCAGC TGGAGAGTGA GCGCGAGGCG CTGCAGCAGC AGCACAGCGT GCAGGTGGAC
CAGCTGCGCA TGCAGGGCCA GAGCGTGGAG GCCGCGCTCC GCATGGAGCG CCAGGCCGCC
TCGGAGGAGA AGAGGAAGCT GGCCCAGTTG CAGGTGGCCT ATCACCAGCT CTTCCAAGAA
TACGACAACC ACATCAAGAG CAGCGTGGTG GGCAGTGAGC GGAAGCGAGG AATGCAGCTG
GAAGATCTCA AACAGCAGCT CCAGCAGGCC GAGGAGGCCC TGGTGGCCAA ACAGGAGGTG
ATCGATAAGC TGAAGGAGGA GGCCGAGCAG CACAAGATTG TGATGGAGAC CGTTCCGGTG
CTGAAGGCCC AGGCGGATAT CTACAAGGCG GACTTCCAGG CTGAGAGGCA GGCCCGGGAG
AAGCTGGCCG AGAAGAAGGA GCTCCTGCAG GAGCAGCTGG AGCAGCTGCA GAGGGAGTAC
AGCAAACTGA AGGCCAGCTG TCAGGAGTCG GCCAGGATCG AGGACATGAG GAAGCGGCAT
GTCGAGGTCT CCCAGGCCCC CTTGCCCCCC GCCCCTGCCT ACCTCTCCTC TCCCCTGGCC
CTGCCCAGCC AGAGGAGGAG CCCCCCCGAG GAGCCACCTG ACTTCTGCTG TCCCAAGTGC
CAGTATCAGG CCCCTGATAT GGACACCCTG CAGATACATG TCATGGAGTG CATTGAGTAG

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OHu27518
Clone ID Related Accession (Same CDS sequence) NM_001321396.1 , XM_011531204.1 , NM_003639.4 , NM_001099857.2 , XM_011531205.1
Accession Version XM_011531205.1 Latest version! Documents for ORF clone product in dufault vector
Sequence Information ORF Nucleotide Sequence (Length: 1260bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags COA
ORF Insert Method CloneEZ® Seamless cloning technology
Insert Structure linear
Update Date 2015-03-12
Organism Homo sapiens(Human)
Product NF-kappa-B essential modulator isoform X1
Comment

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
ATGAATAGGC ACCTCTGGAA GAGCCAACTG TGTGAGATGG TGCAGCCCAG TGGTGGCCCG 
GCAGCAGATC AGGACGTACT GGGCGAAGAG TCTCCTCTGG GGAAGCCAGC CATGCTGCAC
CTGCCTTCAG AACAGGGCGC TCCTGAGACC CTCCAGCGCT GCCTGGAGGA GAATCAAGAG
CTCCGAGATG CCATCCGGCA GAGCAACCAG ATTCTGCGGG AGCGCTGCGA GGAGCTTCTG
CATTTCCAAG CCAGCCAGAG GGAGGAGAAG GAGTTCCTCA TGTGCAAGTT CCAGGAGGCC
AGGAAACTGG TGGAGAGACT CGGCCTGGAG AAGCTCGATC TGAAGAGGCA GAAGGAGCAG
GCTCTGCGGG AGGTGGAGCA CCTGAAGAGA TGCCAGCAGC AGATGGCTGA GGACAAGGCC
TCTGTGAAAG CCCAGGTGAC GTCCTTGCTC GGGGAGCTGC AGGAGAGCCA GAGTCGCTTG
GAGGCTGCCA CTAAGGAATG CCAGGCTCTG GAGGGTCGGG CCCGGGCGGC CAGCGAGCAG
GCGCGGCAGC TGGAGAGTGA GCGCGAGGCG CTGCAGCAGC AGCACAGCGT GCAGGTGGAC
CAGCTGCGCA TGCAGGGCCA GAGCGTGGAG GCCGCGCTCC GCATGGAGCG CCAGGCCGCC
TCGGAGGAGA AGAGGAAGCT GGCCCAGTTG CAGGTGGCCT ATCACCAGCT CTTCCAAGAA
TACGACAACC ACATCAAGAG CAGCGTGGTG GGCAGTGAGC GGAAGCGAGG AATGCAGCTG
GAAGATCTCA AACAGCAGCT CCAGCAGGCC GAGGAGGCCC TGGTGGCCAA ACAGGAGGTG
ATCGATAAGC TGAAGGAGGA GGCCGAGCAG CACAAGATTG TGATGGAGAC CGTTCCGGTG
CTGAAGGCCC AGGCGGATAT CTACAAGGCG GACTTCCAGG CTGAGAGGCA GGCCCGGGAG
AAGCTGGCCG AGAAGAAGGA GCTCCTGCAG GAGCAGCTGG AGCAGCTGCA GAGGGAGTAC
AGCAAACTGA AGGCCAGCTG TCAGGAGTCG GCCAGGATCG AGGACATGAG GAAGCGGCAT
GTCGAGGTCT CCCAGGCCCC CTTGCCCCCC GCCCCTGCCT ACCTCTCCTC TCCCCTGGCC
CTGCCCAGCC AGAGGAGGAG CCCCCCCGAG GAGCCACCTG ACTTCTGCTG TCCCAAGTGC
CAGTATCAGG CCCCTGATAT GGACACCCTG CAGATACATG TCATGGAGTG CATTGAGTAG

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq XP_011529507.1
Translation

Target ORF information:

RefSeq Version XM_011531205.1
Organism Homo sapiens(Human)
Definition Homo sapiens inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma (IKBKG), transcript variant X5, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
XM_011531205.1

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
ATGAATAGGC ACCTCTGGAA GAGCCAACTG TGTGAGATGG TGCAGCCCAG TGGTGGCCCG 
GCAGCAGATC AGGACGTACT GGGCGAAGAG TCTCCTCTGG GGAAGCCAGC CATGCTGCAC
CTGCCTTCAG AACAGGGCGC TCCTGAGACC CTCCAGCGCT GCCTGGAGGA GAATCAAGAG
CTCCGAGATG CCATCCGGCA GAGCAACCAG ATTCTGCGGG AGCGCTGCGA GGAGCTTCTG
CATTTCCAAG CCAGCCAGAG GGAGGAGAAG GAGTTCCTCA TGTGCAAGTT CCAGGAGGCC
AGGAAACTGG TGGAGAGACT CGGCCTGGAG AAGCTCGATC TGAAGAGGCA GAAGGAGCAG
GCTCTGCGGG AGGTGGAGCA CCTGAAGAGA TGCCAGCAGC AGATGGCTGA GGACAAGGCC
TCTGTGAAAG CCCAGGTGAC GTCCTTGCTC GGGGAGCTGC AGGAGAGCCA GAGTCGCTTG
GAGGCTGCCA CTAAGGAATG CCAGGCTCTG GAGGGTCGGG CCCGGGCGGC CAGCGAGCAG
GCGCGGCAGC TGGAGAGTGA GCGCGAGGCG CTGCAGCAGC AGCACAGCGT GCAGGTGGAC
CAGCTGCGCA TGCAGGGCCA GAGCGTGGAG GCCGCGCTCC GCATGGAGCG CCAGGCCGCC
TCGGAGGAGA AGAGGAAGCT GGCCCAGTTG CAGGTGGCCT ATCACCAGCT CTTCCAAGAA
TACGACAACC ACATCAAGAG CAGCGTGGTG GGCAGTGAGC GGAAGCGAGG AATGCAGCTG
GAAGATCTCA AACAGCAGCT CCAGCAGGCC GAGGAGGCCC TGGTGGCCAA ACAGGAGGTG
ATCGATAAGC TGAAGGAGGA GGCCGAGCAG CACAAGATTG TGATGGAGAC CGTTCCGGTG
CTGAAGGCCC AGGCGGATAT CTACAAGGCG GACTTCCAGG CTGAGAGGCA GGCCCGGGAG
AAGCTGGCCG AGAAGAAGGA GCTCCTGCAG GAGCAGCTGG AGCAGCTGCA GAGGGAGTAC
AGCAAACTGA AGGCCAGCTG TCAGGAGTCG GCCAGGATCG AGGACATGAG GAAGCGGCAT
GTCGAGGTCT CCCAGGCCCC CTTGCCCCCC GCCCCTGCCT ACCTCTCCTC TCCCCTGGCC
CTGCCCAGCC AGAGGAGGAG CCCCCCCGAG GAGCCACCTG ACTTCTGCTG TCCCAAGTGC
CAGTATCAGG CCCCTGATAT GGACACCCTG CAGATACATG TCATGGAGTG CATTGAGTAG

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OHu16932
Clone ID Related Accession (Same CDS sequence) NM_001099856.4
Accession Version NM_001099856.4 Latest version! Documents for ORF clone product in dufault vector
Sequence Information ORF Nucleotide Sequence (Length: 1464bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ® Seamless cloning technology
Insert Structure linear
Update Date 2017-04-09
Organism Homo sapiens(Human)
Product NF-kappa-B essential modulator isoform b
Comment REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from BM473416.1, AY114157.1, BC000299.2 and AF062089.1. On Mar 23, 2016 this sequence version replaced NM_001099856.3. Transcript Variant: This variant (2) uses an alternate promoter and initiates translation from an alternate in-frame upstream start codon compared to variant 1. The resulting isoform (b) has a longer N-terminus compared to isoform a. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AY114157.1, BC012114.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2142670, SAMEA2142680 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
ATGGCCCTTG TGATCCAGGT GGGGAAACTA AGGCCCAGAG AAGTGAGGAC CCCGCAGACT 
ATCAATCCCA GTCTCTTCCC CTCACTCCCT GTGAAGCTCT CCAGCATCAT CGAGGTCCCA
TCAGGTGGGG AAAGATGCTG TTCCAGGCGC ACACTAGTCT ACAAGGCCAG AGCTTTCTGG
AAGGGGGCAC CCTTGCCCTG TTGGATGAAT AGGCACCTCT GGAAGAGCCA ACTGTGTGAG
ATGGTGCAGC CCAGTGGTGG CCCGGCAGCA GATCAGGACG TACTGGGCGA AGAGTCTCCT
CTGGGGAAGC CAGCCATGCT GCACCTGCCT TCAGAACAGG GCGCTCCTGA GACCCTCCAG
CGCTGCCTGG AGGAGAATCA AGAGCTCCGA GATGCCATCC GGCAGAGCAA CCAGATTCTG
CGGGAGCGCT GCGAGGAGCT TCTGCATTTC CAAGCCAGCC AGAGGGAGGA GAAGGAGTTC
CTCATGTGCA AGTTCCAGGA GGCCAGGAAA CTGGTGGAGA GACTCGGCCT GGAGAAGCTC
GATCTGAAGA GGCAGAAGGA GCAGGCTCTG CGGGAGGTGG AGCACCTGAA GAGATGCCAG
CAGCAGATGG CTGAGGACAA GGCCTCTGTG AAAGCCCAGG TGACGTCCTT GCTCGGGGAG
CTGCAGGAGA GCCAGAGTCG CTTGGAGGCT GCCACTAAGG AATGCCAGGC TCTGGAGGGT
CGGGCCCGGG CGGCCAGCGA GCAGGCGCGG CAGCTGGAGA GTGAGCGCGA GGCGCTGCAG
CAGCAGCACA GCGTGCAGGT GGACCAGCTG CGCATGCAGG GCCAGAGCGT GGAGGCCGCG
CTCCGCATGG AGCGCCAGGC CGCCTCGGAG GAGAAGAGGA AGCTGGCCCA GTTGCAGGTG
GCCTATCACC AGCTCTTCCA AGAATACGAC AACCACATCA AGAGCAGCGT GGTGGGCAGT
GAGCGGAAGC GAGGAATGCA GCTGGAAGAT CTCAAACAGC AGCTCCAGCA GGCCGAGGAG
GCCCTGGTGG CCAAACAGGA GGTGATCGAT AAGCTGAAGG AGGAGGCCGA GCAGCACAAG
ATTGTGATGG AGACCGTTCC GGTGCTGAAG GCCCAGGCGG ATATCTACAA GGCGGACTTC
CAGGCTGAGA GGCAGGCCCG GGAGAAGCTG GCCGAGAAGA AGGAGCTCCT GCAGGAGCAG
CTGGAGCAGC TGCAGAGGGA GTACAGCAAA CTGAAGGCCA GCTGTCAGGA GTCGGCCAGG
ATCGAGGACA TGAGGAAGCG GCATGTCGAG GTCTCCCAGG CCCCCTTGCC CCCCGCCCCT
GCCTACCTCT CCTCTCCCCT GGCCCTGCCC AGCCAGAGGA GGAGCCCCCC CGAGGAGCCA
CCTGACTTCT GCTGTCCCAA GTGCCAGTAT CAGGCCCCTG ATATGGACAC CCTGCAGATA
CATGTCATGG AGTGCATTGA GTAG

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq NP_001093326.2
CDS25..1488
Misc Feature(1)7..9
Misc Feature(2)358..561
Misc Feature(3)1003..1260
Misc Feature(4)order(1003..1008,1015..1020,1024..1029,1036..1038,1045..1050,1057..1062,1066..1071,1078..1080,1090..1092,1099..1101,1120..1122,1129..1131,1138..1143,1150..1152,1159..1164,1171..1176,1180..1185,1192..1197,1204..1206,1216..1218,1225..1227,1237..1239,1246..1248)
Misc Feature(5)order(1114..1116,1126..1131,1135..1140,1147..1155,1159..1164,1168..1176,1183..1188,1195..1200,1207..1209)
Exon (1)1..213
Exon (2)214..415
Exon (3)416..627
Exon (4)628..746
Exon (5)747..899
Exon (6)900..996
Exon (7)997..1140
Exon (8)1141..1283
Exon (9)1284..1345
Exon (10)1346..2073
Translation

Target ORF information:

RefSeq Version NM_001099856.4
Organism Homo sapiens(Human)
Definition Homo sapiens inhibitor of nuclear factor kappa B kinase subunit gamma (IKBKG), transcript variant 2, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
NM_001099856.4

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
ATGGCCCTTG TGATCCAGGT GGGGAAACTA AGGCCCAGAG AAGTGAGGAC CCCGCAGACT 
ATCAATCCCA GTCTCTTCCC CTCACTCCCT GTGAAGCTCT CCAGCATCAT CGAGGTCCCA
TCAGGTGGGG AAAGATGCTG TTCCAGGCGC ACACTAGTCT ACAAGGCCAG AGCTTTCTGG
AAGGGGGCAC CCTTGCCCTG TTGGATGAAT AGGCACCTCT GGAAGAGCCA ACTGTGTGAG
ATGGTGCAGC CCAGTGGTGG CCCGGCAGCA GATCAGGACG TACTGGGCGA AGAGTCTCCT
CTGGGGAAGC CAGCCATGCT GCACCTGCCT TCAGAACAGG GCGCTCCTGA GACCCTCCAG
CGCTGCCTGG AGGAGAATCA AGAGCTCCGA GATGCCATCC GGCAGAGCAA CCAGATTCTG
CGGGAGCGCT GCGAGGAGCT TCTGCATTTC CAAGCCAGCC AGAGGGAGGA GAAGGAGTTC
CTCATGTGCA AGTTCCAGGA GGCCAGGAAA CTGGTGGAGA GACTCGGCCT GGAGAAGCTC
GATCTGAAGA GGCAGAAGGA GCAGGCTCTG CGGGAGGTGG AGCACCTGAA GAGATGCCAG
CAGCAGATGG CTGAGGACAA GGCCTCTGTG AAAGCCCAGG TGACGTCCTT GCTCGGGGAG
CTGCAGGAGA GCCAGAGTCG CTTGGAGGCT GCCACTAAGG AATGCCAGGC TCTGGAGGGT
CGGGCCCGGG CGGCCAGCGA GCAGGCGCGG CAGCTGGAGA GTGAGCGCGA GGCGCTGCAG
CAGCAGCACA GCGTGCAGGT GGACCAGCTG CGCATGCAGG GCCAGAGCGT GGAGGCCGCG
CTCCGCATGG AGCGCCAGGC CGCCTCGGAG GAGAAGAGGA AGCTGGCCCA GTTGCAGGTG
GCCTATCACC AGCTCTTCCA AGAATACGAC AACCACATCA AGAGCAGCGT GGTGGGCAGT
GAGCGGAAGC GAGGAATGCA GCTGGAAGAT CTCAAACAGC AGCTCCAGCA GGCCGAGGAG
GCCCTGGTGG CCAAACAGGA GGTGATCGAT AAGCTGAAGG AGGAGGCCGA GCAGCACAAG
ATTGTGATGG AGACCGTTCC GGTGCTGAAG GCCCAGGCGG ATATCTACAA GGCGGACTTC
CAGGCTGAGA GGCAGGCCCG GGAGAAGCTG GCCGAGAAGA AGGAGCTCCT GCAGGAGCAG
CTGGAGCAGC TGCAGAGGGA GTACAGCAAA CTGAAGGCCA GCTGTCAGGA GTCGGCCAGG
ATCGAGGACA TGAGGAAGCG GCATGTCGAG GTCTCCCAGG CCCCCTTGCC CCCCGCCCCT
GCCTACCTCT CCTCTCCCCT GGCCCTGCCC AGCCAGAGGA GGAGCCCCCC CGAGGAGCCA
CCTGACTTCT GCTGTCCCAA GTGCCAGTAT CAGGCCCCTG ATATGGACAC CCTGCAGATA
CATGTCATGG AGTGCATTGA GTAG

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OHu27490
Clone ID Related Accession (Same CDS sequence) NM_001145255.2
Accession Version NM_001145255.2 Latest version! Documents for ORF clone product in dufault vector
Sequence Information ORF Nucleotide Sequence (Length: 963bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ® Seamless cloning technology
Insert Structure linear
Update Date 2017-04-09
Organism Homo sapiens(Human)
Product NF-kappa-B essential modulator isoform c
Comment REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AK308366.1, AK000593.1, BC000299.2 and AF062089.1. On Sep 17, 2013 this sequence version replaced NM_001145255.1. Transcript Variant: This variant (4) lacks two in-frame exons in the central coding region compared to variant 1. The resulting isoform (c) lacks two internal protein segments compared to isoform a. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AK000593.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2154529 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
ATGAATAGGC ACCTCTGGAA GAGCCAACTG TGTGAGATGG TGCAGCCCAG TGGTGGCCCG 
GCAGCAGATC AGGACGTACT GGGCGAAGAG TCTCCTCTGG GGAAGCCAGC CATGCTGCAC
CTGCCTTCAG AACAGGGCGC TCCTGAGACC CTCCAGCGCT GCCTGGAGGA GAATCAAGAG
CTCCGAGATG CCATCCGGCA GAGCAACCAG ATTCTGCGGG AGCGCTGCGA GGAGCTTCTG
CATTTCCAAG CCAGCCAGAG GGAGGAGAAG GAGTTCCTCA TGTGCAAGTT CCAGGAGGCC
AGGAAACTGG TGGAGAGACT CGGCCTGGAG AAGCTCGATC TGAAGAGGCA GAAGGAGCAG
GCTCTGCGGG AGGTGGAGCA CCTGAAGAGA TGCCAGCAGC AGATGGCTGA GGACAAGGCC
TCTGTGAAAG CCCAGGTGAC GTCCTTGCTC GGGGAGCTGC AGGAGAGCCA GAGTCGCTTG
GAGGCTGCCA CTAAGGAATG CCAGGCTCTG GAGGGTCGGA GGAAGCTGGC CCAGTTGCAG
GTGGCCTATC ACCAGCTCTT CCAAGAATAC GACAACCACA TCAAGAGCAG CGTGGTGGGC
AGTGAGCGGA AGCGAGCGGA TATCTACAAG GCGGACTTCC AGGCTGAGAG GCAGGCCCGG
GAGAAGCTGG CCGAGAAGAA GGAGCTCCTG CAGGAGCAGC TGGAGCAGCT GCAGAGGGAG
TACAGCAAAC TGAAGGCCAG CTGTCAGGAG TCGGCCAGGA TCGAGGACAT GAGGAAGCGG
CATGTCGAGG TCTCCCAGGC CCCCTTGCCC CCCGCCCCTG CCTACCTCTC CTCTCCCCTG
GCCCTGCCCA GCCAGAGGAG GAGCCCCCCC GAGGAGCCAC CTGACTTCTG CTGTCCCAAG
TGCCAGTATC AGGCCCCTGA TATGGACACC CTGCAGATAC ATGTCATGGA GTGCATTGAG
TAG

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq NP_001138727.1
CDS415..1377
Misc Feature(1)394..396
Misc Feature(2)544..747
Misc Feature(3)<1021..1149
Misc Feature(4)order(1024..1029,1036..1044,1048..1053,1057..1065,1072..1077,1084..1089,1096..1098)
Exon (1)1..399
Exon (2)400..601
Exon (3)602..813
Exon (4)814..932
Exon (5)933..1029
Exon (6)1030..1172
Exon (7)1173..1234
Exon (8)1235..1962
Translation

Target ORF information:

RefSeq Version NM_001145255.2
Organism Homo sapiens(Human)
Definition Homo sapiens inhibitor of nuclear factor kappa B kinase subunit gamma (IKBKG), transcript variant 4, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
NM_001145255.2

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
ATGAATAGGC ACCTCTGGAA GAGCCAACTG TGTGAGATGG TGCAGCCCAG TGGTGGCCCG 
GCAGCAGATC AGGACGTACT GGGCGAAGAG TCTCCTCTGG GGAAGCCAGC CATGCTGCAC
CTGCCTTCAG AACAGGGCGC TCCTGAGACC CTCCAGCGCT GCCTGGAGGA GAATCAAGAG
CTCCGAGATG CCATCCGGCA GAGCAACCAG ATTCTGCGGG AGCGCTGCGA GGAGCTTCTG
CATTTCCAAG CCAGCCAGAG GGAGGAGAAG GAGTTCCTCA TGTGCAAGTT CCAGGAGGCC
AGGAAACTGG TGGAGAGACT CGGCCTGGAG AAGCTCGATC TGAAGAGGCA GAAGGAGCAG
GCTCTGCGGG AGGTGGAGCA CCTGAAGAGA TGCCAGCAGC AGATGGCTGA GGACAAGGCC
TCTGTGAAAG CCCAGGTGAC GTCCTTGCTC GGGGAGCTGC AGGAGAGCCA GAGTCGCTTG
GAGGCTGCCA CTAAGGAATG CCAGGCTCTG GAGGGTCGGA GGAAGCTGGC CCAGTTGCAG
GTGGCCTATC ACCAGCTCTT CCAAGAATAC GACAACCACA TCAAGAGCAG CGTGGTGGGC
AGTGAGCGGA AGCGAGCGGA TATCTACAAG GCGGACTTCC AGGCTGAGAG GCAGGCCCGG
GAGAAGCTGG CCGAGAAGAA GGAGCTCCTG CAGGAGCAGC TGGAGCAGCT GCAGAGGGAG
TACAGCAAAC TGAAGGCCAG CTGTCAGGAG TCGGCCAGGA TCGAGGACAT GAGGAAGCGG
CATGTCGAGG TCTCCCAGGC CCCCTTGCCC CCCGCCCCTG CCTACCTCTC CTCTCCCCTG
GCCCTGCCCA GCCAGAGGAG GAGCCCCCCC GAGGAGCCAC CTGACTTCTG CTGTCCCAAG
TGCCAGTATC AGGCCCCTGA TATGGACACC CTGCAGATAC ATGTCATGGA GTGCATTGAG
TAG

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OHu54458
Clone ID Related Accession (Same CDS sequence) NM_001321397.1
Accession Version NM_001321397.1 Latest version! Documents for ORF clone product in dufault vector
Sequence Information ORF Nucleotide Sequence (Length: 1257bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ® Seamless cloning technology
Insert Structure linear
Update Date 2017-04-30
Organism Homo sapiens(Human)
Product NF-kappa-B essential modulator isoform d
Comment REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AK308366.1, CA916723.1, BC000299.2 and AF062089.1. On Mar 23, 2016 this sequence version replaced XM_005274764.3. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1163655.117630.1, CA916723.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1968189 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
ATGAATAGGC ACCTCTGGAA GAGCCAACTG TGTGAGATGG TGCAGCCCAG TGGTGGCCCG 
GCAGCAGATC AGGACGTACT GGGCGAAGAG TCTCCTCTGG GGAAGCCAGC CATGCTGCAC
CTGCCTTCAG AACAGGGCGC TCCTGAGACC CTCCAGCGCT GCCTGGAGGA GAATCAAGAG
CTCCGAGATG CCATCCGGCA GAGCAACCAG ATTCTGCGGG AGCGCTGCGA GGAGCTTCTG
CATTTCCAAG CCAGCCAGAG GGAGGAGAAG GAGTTCCTCA TGTGCAAGTT CCAGGAGGCC
AGGAAACTGG TGGAGAGACT CGGCCTGGAG AAGCTCGATC TGAAGAGGCA GAAGGAGCAG
GCTCTGCGGG AGGTGGAGCA CCTGAAGAGA TGCCAGCAGA TGGCTGAGGA CAAGGCCTCT
GTGAAAGCCC AGGTGACGTC CTTGCTCGGG GAGCTGCAGG AGAGCCAGAG TCGCTTGGAG
GCTGCCACTA AGGAATGCCA GGCTCTGGAG GGTCGGGCCC GGGCGGCCAG CGAGCAGGCG
CGGCAGCTGG AGAGTGAGCG CGAGGCGCTG CAGCAGCAGC ACAGCGTGCA GGTGGACCAG
CTGCGCATGC AGGGCCAGAG CGTGGAGGCC GCGCTCCGCA TGGAGCGCCA GGCCGCCTCG
GAGGAGAAGA GGAAGCTGGC CCAGTTGCAG GTGGCCTATC ACCAGCTCTT CCAAGAATAC
GACAACCACA TCAAGAGCAG CGTGGTGGGC AGTGAGCGGA AGCGAGGAAT GCAGCTGGAA
GATCTCAAAC AGCAGCTCCA GCAGGCCGAG GAGGCCCTGG TGGCCAAACA GGAGGTGATC
GATAAGCTGA AGGAGGAGGC CGAGCAGCAC AAGATTGTGA TGGAGACCGT TCCGGTGCTG
AAGGCCCAGG CGGATATCTA CAAGGCGGAC TTCCAGGCTG AGAGGCAGGC CCGGGAGAAG
CTGGCCGAGA AGAAGGAGCT CCTGCAGGAG CAGCTGGAGC AGCTGCAGAG GGAGTACAGC
AAACTGAAGG CCAGCTGTCA GGAGTCGGCC AGGATCGAGG ACATGAGGAA GCGGCATGTC
GAGGTCTCCC AGGCCCCCTT GCCCCCCGCC CCTGCCTACC TCTCCTCTCC CCTGGCCCTG
CCCAGCCAGA GGAGGAGCCC CCCCGAGGAG CCACCTGACT TCTGCTGTCC CAAGTGCCAG
TATCAGGCCC CTGATATGGA CACCCTGCAG ATACATGTCA TGGAGTGCAT TGAGTAG

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq NP_001308326.1
CDS415..1671
Misc Feature(1)394..396
Misc Feature(2)505..507
Misc Feature(3)541..543
Misc Feature(4)544..747
Misc Feature(5)544..747
Misc Feature(6)616..618
Misc Feature(7)667..669
Misc Feature(8)859..1182
Misc Feature(9)1135..1461
Misc Feature(10)1147..1506
Misc Feature(11)1162..1668
Misc Feature(12)1186..1443
Misc Feature(13)order(1186..1191,1198..1203,1207..1212,1219..1221,1228..1233,1240..1245,1249..1254,1261..1263,1273..1275,1282..1284,1303..1305,1312..1314,1321..1326,1333..1335,1342..1347,1354..1359,1363..1368,1375..1380,1387..1389,1399..1401,1408..1410,1420..1422,1429..1431)
Misc Feature(14)order(1297..1299,1309..1314,1318..1323,1330..1338,1342..1347,1351..1359,1366..1371,1378..1383,1390..1392)
Misc Feature(15)1375..1440
Misc Feature(16)1537..1539
Misc Feature(17)1555..1668
Misc Feature(18)1570..1572
Exon (1)1..399
Exon (2)400..601
Exon (3)602..813
Exon (4)814..929
Exon (5)930..1082
Exon (6)1083..1179
Exon (7)1180..1323
Exon (8)1324..1466
Exon (9)1467..1528
Exon (10)1529..2256
Translation

Target ORF information:

RefSeq Version NM_001321397.1
Organism Homo sapiens(Human)
Definition Homo sapiens inhibitor of nuclear factor kappa B kinase subunit gamma (IKBKG), transcript variant 6, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
NM_001321397.1

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
ATGAATAGGC ACCTCTGGAA GAGCCAACTG TGTGAGATGG TGCAGCCCAG TGGTGGCCCG 
GCAGCAGATC AGGACGTACT GGGCGAAGAG TCTCCTCTGG GGAAGCCAGC CATGCTGCAC
CTGCCTTCAG AACAGGGCGC TCCTGAGACC CTCCAGCGCT GCCTGGAGGA GAATCAAGAG
CTCCGAGATG CCATCCGGCA GAGCAACCAG ATTCTGCGGG AGCGCTGCGA GGAGCTTCTG
CATTTCCAAG CCAGCCAGAG GGAGGAGAAG GAGTTCCTCA TGTGCAAGTT CCAGGAGGCC
AGGAAACTGG TGGAGAGACT CGGCCTGGAG AAGCTCGATC TGAAGAGGCA GAAGGAGCAG
GCTCTGCGGG AGGTGGAGCA CCTGAAGAGA TGCCAGCAGA TGGCTGAGGA CAAGGCCTCT
GTGAAAGCCC AGGTGACGTC CTTGCTCGGG GAGCTGCAGG AGAGCCAGAG TCGCTTGGAG
GCTGCCACTA AGGAATGCCA GGCTCTGGAG GGTCGGGCCC GGGCGGCCAG CGAGCAGGCG
CGGCAGCTGG AGAGTGAGCG CGAGGCGCTG CAGCAGCAGC ACAGCGTGCA GGTGGACCAG
CTGCGCATGC AGGGCCAGAG CGTGGAGGCC GCGCTCCGCA TGGAGCGCCA GGCCGCCTCG
GAGGAGAAGA GGAAGCTGGC CCAGTTGCAG GTGGCCTATC ACCAGCTCTT CCAAGAATAC
GACAACCACA TCAAGAGCAG CGTGGTGGGC AGTGAGCGGA AGCGAGGAAT GCAGCTGGAA
GATCTCAAAC AGCAGCTCCA GCAGGCCGAG GAGGCCCTGG TGGCCAAACA GGAGGTGATC
GATAAGCTGA AGGAGGAGGC CGAGCAGCAC AAGATTGTGA TGGAGACCGT TCCGGTGCTG
AAGGCCCAGG CGGATATCTA CAAGGCGGAC TTCCAGGCTG AGAGGCAGGC CCGGGAGAAG
CTGGCCGAGA AGAAGGAGCT CCTGCAGGAG CAGCTGGAGC AGCTGCAGAG GGAGTACAGC
AAACTGAAGG CCAGCTGTCA GGAGTCGGCC AGGATCGAGG ACATGAGGAA GCGGCATGTC
GAGGTCTCCC AGGCCCCCTT GCCCCCCGCC CCTGCCTACC TCTCCTCTCC CCTGGCCCTG
CCCAGCCAGA GGAGGAGCCC CCCCGAGGAG CCACCTGACT TCTGCTGTCC CAAGTGCCAG
TATCAGGCCC CTGATATGGA CACCCTGCAG ATACATGTCA TGGAGTGCAT TGAGTAG

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

book

Targeting Non-proteolytic Protein Ubiquitination for the Treatment of Diffuse Large B Cell Lymphoma.
Cancer cell29(4)494-507(2016 Apr)
Yang Y,Kelly P,Shaffer AL 3rd,Schmitz R,Yoo HM,Liu X,Huang DW,Webster D,Young RM,Nakagawa M,Ceribelli M,Wright GW,Yang Y,Zhao H,Yu X,Xu W,Chan WC,Jaffe ES,Gascoyne RD,Campo E,Rosenwald A,Ott G,Delabie J,Rimsza L,Staudt LM


book

Distinct Activation Mechanisms of NF-κB Regulator Inhibitor of NF-κB Kinase (IKK) by Isoforms of the Cell Death Regulator Cellular FLICE-like Inhibitory Protein (cFLIP).
The Journal of biological chemistry291(14)7608-20(2016 Apr)
Baratchian M,Davis CA,Shimizu A,Escors D,Bagnéris C,Barrett T,Collins MK


book

Recruitment of A20 by the C-terminal domain of NEMO suppresses NF-κB activation and autoinflammatory disease.
Proceedings of the National Academy of Sciences of the United States of America113(6)1612-7(2016 Feb)
Zilberman-Rudenko J,Shawver LM,Wessel AW,Luo Y,Pelletier M,Tsai WL,Lee Y,Vonortas S,Cheng L,Ashwell JD,Orange JS,Siegel RM,Hanson EP


book

Autoubiquitination of TRIM26 links TBK1 to NEMO in RLR-mediated innate antiviral immune response.
Journal of molecular cell biology8(1)31-43(2016 Feb)
Ran Y,Zhang J,Liu LL,Pan ZY,Nie Y,Zhang HY,Wang YY


 
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