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TNFRSF10B cDNA ORF clone, Homo sapiens (human)

Gene Symbol TNFRSF10B
Entrez Gene ID 8795
Full Name tumor necrosis factor receptor superfamily, member 10b
Synonyms CD262, DR5, KILLER, KILLER/DR5, TRAIL-R2, TRAILR2, TRICK2, TRICK2A, TRICK2B, TRICKB, ZTNFR9
General protein information
Preferred Names
tumor necrosis factor receptor superfamily member 10B
Names
tumor necrosis factor receptor superfamily member 10B
Fas-like protein
death receptor 5
cytotoxic TRAIL receptor-2
apoptosis inducing receptor TRAIL-R2
apoptosis inducing protein TRICK2A/2B
TNF-related apoptosis-inducing ligand receptor 2
death domain containing receptor for TRAIL/Apo-2L
tumor necrosis factor receptor-like protein ZTNFR9
p53-regulated DNA damage-inducible cell death receptor(killer)
Gene Type protein-coding
Organism Homo sapiens (human)
Genome

8

8p22-p21

Summary The protein encoded by this gene is a member of the TNF-receptor superfamily, and contains an intracellular death domain. This receptor can be activated by tumor necrosis factor-related apoptosis inducing ligand (TNFSF10/TRAIL/APO-2L), and transduces an apoptosis signal. Studies with FADD-deficient mice suggested that FADD, a death domain containing adaptor protein, is required for the apoptosis mediated by this protein. Two transcript variants encoding different isoforms and one non-coding transcript have been found for this gene. [provided by RefSeq, Mar 2009]. lac of sum
Disorder MIM:

603612

Disorder Html: Squamous cell carcinoma, head and neck, 275355 (3)

mRNA and Protein(s)

mRNA Protein Name
NM_003842 NP_003833 tumor necrosis factor receptor superfamily member 10B isoform 1 precursor
NM_147187 NP_671716 tumor necrosis factor receptor superfamily member 10B isoform 2 precursor



Homo sapiens (human) TNFRSF10B NP_003833.4
Pan troglodytes (chimpanzee) TNFRSF10B XP_001158074.1
Macaca mulatta (Rhesus monkey) LOC716650 XP_001107490.2
Gallus gallus (chicken) TNFRSF10B NP_989446.2
Xenopus (Silurana) tropicalis (western clawed frog) tnfrsf10b NP_001004894.1


GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following TNFRSF10B gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the TNFRSF10B cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID RefSeq Accession Definition **Vector *Turnaround time Price Select
OHu22693 NM_003842 Homo sapiens tumor necrosis factor receptor superfamily, member 10b (TNFRSF10B), transcript variant 1, mRNA. pcDNA3.1+/C-(K)DYK or customized vector 7-9 $223.30
$319.00
OHu15833 NM_147187 Homo sapiens tumor necrosis factor receptor superfamily, member 10b (TNFRSF10B), transcript variant 2, mRNA. pcDNA3.1+/C-(K)DYK or customized vector 7-9 $244.30
$349.00
Next-day Shipping ORF Clones ( in default vector with tag)
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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.


CloneID OHu22693
Clone ID Related Accession (Same CDS sequence) NM_003842
Accession Version NM_003842.4 Documents for ORF clone product in dufault vector
Sequence Information ORF Nucleotide Sequence (Length: 1323bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ® Seamless cloning technology
Structure linear
Update Date 15-MAR-2015
Organism Homo sapiens (human)
Product tumor necrosis factor receptor superfamily member 10B isoform 1 precursor
Comment REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from DA738472.1, DA889488.1, BC001281.1, CX870630.1, BX537617.1 and AC107959.8. This sequence is a reference standard in the RefSeqGene project. On Mar 4, 2009 this sequence version replaced gi:22547115. Transcript Variant: This variant (1) represents the longest transcript and encodes the longer isoform (1). Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AF016266.1, AK291216.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2149398, SAMEA962343 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
ATGGAACAAC GGGGACAGAA CGCCCCGGCC GCTTCGGGGG CCCGGAAAAG GCACGGCCCA 
GGACCCAGGG AGGCGCGGGG AGCCAGGCCT GGGCCCCGGG TCCCCAAGAC CCTTGTGCTC
GTTGTCGCCG CGGTCCTGCT GTTGGTCTCA GCTGAGTCTG CTCTGATCAC CCAACAAGAC
CTAGCTCCCC AGCAGAGAGC GGCCCCACAA CAAAAGAGGT CCAGCCCCTC AGAGGGATTG
TGTCCACCTG GACACCATAT CTCAGAAGAC GGTAGAGATT GCATCTCCTG CAAATATGGA
CAGGACTATA GCACTCACTG GAATGACCTC CTTTTCTGCT TGCGCTGCAC CAGGTGTGAT
TCAGGTGAAG TGGAGCTAAG TCCCTGCACC ACGACCAGAA ACACAGTGTG TCAGTGCGAA
GAAGGCACCT TCCGGGAAGA AGATTCTCCT GAGATGTGCC GGAAGTGCCG CACAGGGTGT
CCCAGAGGGA TGGTCAAGGT CGGTGATTGT ACACCCTGGA GTGACATCGA ATGTGTCCAC
AAAGAATCAG GTACAAAGCA CAGTGGGGAA GTCCCAGCTG TGGAGGAGAC GGTGACCTCC
AGCCCAGGGA CTCCTGCCTC TCCCTGTTCT CTCTCAGGCA TCATCATAGG AGTCACAGTT
GCAGCCGTAG TCTTGATTGT GGCTGTGTTT GTTTGCAAGT CTTTACTGTG GAAGAAAGTC
CTTCCTTACC TGAAAGGCAT CTGCTCAGGT GGTGGTGGGG ACCCTGAGCG TGTGGACAGA
AGCTCACAAC GACCTGGGGC TGAGGACAAT GTCCTCAATG AGATCGTGAG TATCTTGCAG
CCCACCCAGG TCCCTGAGCA GGAAATGGAA GTCCAGGAGC CAGCAGAGCC AACAGGTGTC
AACATGTTGT CCCCCGGGGA GTCAGAGCAT CTGCTGGAAC CGGCAGAAGC TGAAAGGTCT
CAGAGGAGGA GGCTGCTGGT TCCAGCAAAT GAAGGTGATC CCACTGAGAC TCTGAGACAG
TGCTTCGATG ACTTTGCAGA CTTGGTGCCC TTTGACTCCT GGGAGCCGCT CATGAGGAAG
TTGGGCCTCA TGGACAATGA GATAAAGGTG GCTAAAGCTG AGGCAGCGGG CCACAGGGAC
ACCTTGTACA CGATGCTGAT AAAGTGGGTC AACAAAACCG GGCGAGATGC CTCTGTCCAC
ACCCTGCTGG ATGCCTTGGA GACGCTGGGA GAGAGACTTG CCAAGCAGAA GATTGAGGAC
CACTTGTTGA GCTCTGGAAA GTTCATGTAT CTAGAAGGTA ATGCAGACTC TGCCATGTCC
TAA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq NP_003833.4
CDS294..1616
Misc Feature(1)264..266(+)
Misc Feature(2)462..575(+)
Misc Feature(3)522..830(+)
Misc Feature(4)522..575(+)
Misc Feature(5)525..818(+)
Misc Feature(6)582..704(+)
Misc Feature(7)582..704(+)
Misc Feature(8)627..758(+)
Misc Feature(9)705..827(+)
Misc Feature(10)708..827(+)
Misc Feature(11)867..911(+)
Misc Feature(12)924..986(+)
Misc Feature(13)1314..1577(+)
Exon (1)1..437
Gene:TNFRSF10B
Gene Synonym:
Exon (2)438..543
Gene:TNFRSF10B
Gene Synonym:
Exon (3)544..657
Gene:TNFRSF10B
Gene Synonym:
Exon (4)658..769
Gene:TNFRSF10B
Gene Synonym:
Exon (5)770..1041
Gene:TNFRSF10B
Gene Synonym:
Exon (6)1042..1073
Gene:TNFRSF10B
Gene Synonym:
Exon (7)1074..1229
Gene:TNFRSF10B
Gene Synonym:
Exon (8)1230..1302
Gene:TNFRSF10B
Gene Synonym:
Exon (9)1303..4154
Gene:TNFRSF10B
Gene Synonym:
Translation

Target ORF information:

RefSeq Version NM_003842
Organism Homo sapiens (human)
Definition Homo sapiens tumor necrosis factor receptor superfamily, member 10b (TNFRSF10B), transcript variant 1, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
NM_003842

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
ATGGAACAAC GGGGACAGAA CGCCCCGGCC GCTTCGGGGG CCCGGAAAAG GCACGGCCCA 
GGACCCAGGG AGGCGCGGGG AGCCAGGCCT GGGCCCCGGG TCCCCAAGAC CCTTGTGCTC
GTTGTCGCCG CGGTCCTGCT GTTGGTCTCA GCTGAGTCTG CTCTGATCAC CCAACAAGAC
CTAGCTCCCC AGCAGAGAGC GGCCCCACAA CAAAAGAGGT CCAGCCCCTC AGAGGGATTG
TGTCCACCTG GACACCATAT CTCAGAAGAC GGTAGAGATT GCATCTCCTG CAAATATGGA
CAGGACTATA GCACTCACTG GAATGACCTC CTTTTCTGCT TGCGCTGCAC CAGGTGTGAT
TCAGGTGAAG TGGAGCTAAG TCCCTGCACC ACGACCAGAA ACACAGTGTG TCAGTGCGAA
GAAGGCACCT TCCGGGAAGA AGATTCTCCT GAGATGTGCC GGAAGTGCCG CACAGGGTGT
CCCAGAGGGA TGGTCAAGGT CGGTGATTGT ACACCCTGGA GTGACATCGA ATGTGTCCAC
AAAGAATCAG GTACAAAGCA CAGTGGGGAA GTCCCAGCTG TGGAGGAGAC GGTGACCTCC
AGCCCAGGGA CTCCTGCCTC TCCCTGTTCT CTCTCAGGCA TCATCATAGG AGTCACAGTT
GCAGCCGTAG TCTTGATTGT GGCTGTGTTT GTTTGCAAGT CTTTACTGTG GAAGAAAGTC
CTTCCTTACC TGAAAGGCAT CTGCTCAGGT GGTGGTGGGG ACCCTGAGCG TGTGGACAGA
AGCTCACAAC GACCTGGGGC TGAGGACAAT GTCCTCAATG AGATCGTGAG TATCTTGCAG
CCCACCCAGG TCCCTGAGCA GGAAATGGAA GTCCAGGAGC CAGCAGAGCC AACAGGTGTC
AACATGTTGT CCCCCGGGGA GTCAGAGCAT CTGCTGGAAC CGGCAGAAGC TGAAAGGTCT
CAGAGGAGGA GGCTGCTGGT TCCAGCAAAT GAAGGTGATC CCACTGAGAC TCTGAGACAG
TGCTTCGATG ACTTTGCAGA CTTGGTGCCC TTTGACTCCT GGGAGCCGCT CATGAGGAAG
TTGGGCCTCA TGGACAATGA GATAAAGGTG GCTAAAGCTG AGGCAGCGGG CCACAGGGAC
ACCTTGTACA CGATGCTGAT AAAGTGGGTC AACAAAACCG GGCGAGATGC CTCTGTCCAC
ACCCTGCTGG ATGCCTTGGA GACGCTGGGA GAGAGACTTG CCAAGCAGAA GATTGAGGAC
CACTTGTTGA GCTCTGGAAA GTTCATGTAT CTAGAAGGTA ATGCAGACTC TGCCATGTCC
TAA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OHu15833
Clone ID Related Accession (Same CDS sequence) NM_147187
Accession Version NM_147187.2 Documents for ORF clone product in dufault vector
Sequence Information ORF Nucleotide Sequence (Length: 1236bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ® Seamless cloning technology
Structure linear
Update Date 15-MAR-2015
Organism Homo sapiens (human)
Product tumor necrosis factor receptor superfamily member 10B isoform 2 precursor
Comment REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from DA738472.1, DA889488.1, BC001281.1, AF192548.1 and AC107959.8. On Mar 4, 2009 this sequence version replaced gi:22547118. Transcript Variant: This variant (2) lacks an in-frame coding segment compared to variant 1. The resulting isoform (2) lacks an internal region, as compared to isoform (1). Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AF012535.1, AY358277.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2149398, SAMEA962343 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
ATGGAACAAC GGGGACAGAA CGCCCCGGCC GCTTCGGGGG CCCGGAAAAG GCACGGCCCA 
GGACCCAGGG AGGCGCGGGG AGCCAGGCCT GGGCCCCGGG TCCCCAAGAC CCTTGTGCTC
GTTGTCGCCG CGGTCCTGCT GTTGGTCTCA GCTGAGTCTG CTCTGATCAC CCAACAAGAC
CTAGCTCCCC AGCAGAGAGC GGCCCCACAA CAAAAGAGGT CCAGCCCCTC AGAGGGATTG
TGTCCACCTG GACACCATAT CTCAGAAGAC GGTAGAGATT GCATCTCCTG CAAATATGGA
CAGGACTATA GCACTCACTG GAATGACCTC CTTTTCTGCT TGCGCTGCAC CAGGTGTGAT
TCAGGTGAAG TGGAGCTAAG TCCCTGCACC ACGACCAGAA ACACAGTGTG TCAGTGCGAA
GAAGGCACCT TCCGGGAAGA AGATTCTCCT GAGATGTGCC GGAAGTGCCG CACAGGGTGT
CCCAGAGGGA TGGTCAAGGT CGGTGATTGT ACACCCTGGA GTGACATCGA ATGTGTCCAC
AAAGAATCAG GCATCATCAT AGGAGTCACA GTTGCAGCCG TAGTCTTGAT TGTGGCTGTG
TTTGTTTGCA AGTCTTTACT GTGGAAGAAA GTCCTTCCTT ACCTGAAAGG CATCTGCTCA
GGTGGTGGTG GGGACCCTGA GCGTGTGGAC AGAAGCTCAC AACGACCTGG GGCTGAGGAC
AATGTCCTCA ATGAGATCGT GAGTATCTTG CAGCCCACCC AGGTCCCTGA GCAGGAAATG
GAAGTCCAGG AGCCAGCAGA GCCAACAGGT GTCAACATGT TGTCCCCCGG GGAGTCAGAG
CATCTGCTGG AACCGGCAGA AGCTGAAAGG TCTCAGAGGA GGAGGCTGCT GGTTCCAGCA
AATGAAGGTG ATCCCACTGA GACTCTGAGA CAGTGCTTCG ATGACTTTGC AGACTTGGTG
CCCTTTGACT CCTGGGAGCC GCTCATGAGG AAGTTGGGCC TCATGGACAA TGAGATAAAG
GTGGCTAAAG CTGAGGCAGC GGGCCACAGG GACACCTTGT ACACGATGCT GATAAAGTGG
GTCAACAAAA CCGGGCGAGA TGCCTCTGTC CACACCCTGC TGGATGCCTT GGAGACGCTG
GGAGAGAGAC TTGCCAAGCA GAAGATTGAG GACCACTTGT TGAGCTCTGG AAAGTTCATG
TATCTAGAAG GTAATGCAGA CTCTGCCATG TCCTAA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq NP_671716.2
CDS294..1529
Misc Feature(1)264..266(+)
Misc Feature(2)522..830(+)
Misc Feature(3)522..575(+)
Misc Feature(4)525..818(+)
Misc Feature(5)582..704(+)
Misc Feature(6)627..758(+)
Misc Feature(7)708..827(+)
Misc Feature(8)1227..1490(+)
Exon (1)1..437
Gene:TNFRSF10B
Gene Synonym:
Exon (2)438..543
Gene:TNFRSF10B
Gene Synonym:
Exon (3)544..657
Gene:TNFRSF10B
Gene Synonym:
Exon (4)658..769
Gene:TNFRSF10B
Gene Synonym:
Exon (5)770..843
Gene:TNFRSF10B
Gene Synonym:
Exon (6)844..954
Gene:TNFRSF10B
Gene Synonym:
Exon (7)955..986
Gene:TNFRSF10B
Gene Synonym:
Exon (8)987..1142
Gene:TNFRSF10B
Gene Synonym:
Exon (9)1143..1215
Gene:TNFRSF10B
Gene Synonym:
Exon (10)1216..4067
Gene:TNFRSF10B
Gene Synonym:
Translation

Target ORF information:

RefSeq Version NM_147187
Organism Homo sapiens (human)
Definition Homo sapiens tumor necrosis factor receptor superfamily, member 10b (TNFRSF10B), transcript variant 2, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
NM_147187

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
ATGGAACAAC GGGGACAGAA CGCCCCGGCC GCTTCGGGGG CCCGGAAAAG GCACGGCCCA 
GGACCCAGGG AGGCGCGGGG AGCCAGGCCT GGGCCCCGGG TCCCCAAGAC CCTTGTGCTC
GTTGTCGCCG CGGTCCTGCT GTTGGTCTCA GCTGAGTCTG CTCTGATCAC CCAACAAGAC
CTAGCTCCCC AGCAGAGAGC GGCCCCACAA CAAAAGAGGT CCAGCCCCTC AGAGGGATTG
TGTCCACCTG GACACCATAT CTCAGAAGAC GGTAGAGATT GCATCTCCTG CAAATATGGA
CAGGACTATA GCACTCACTG GAATGACCTC CTTTTCTGCT TGCGCTGCAC CAGGTGTGAT
TCAGGTGAAG TGGAGCTAAG TCCCTGCACC ACGACCAGAA ACACAGTGTG TCAGTGCGAA
GAAGGCACCT TCCGGGAAGA AGATTCTCCT GAGATGTGCC GGAAGTGCCG CACAGGGTGT
CCCAGAGGGA TGGTCAAGGT CGGTGATTGT ACACCCTGGA GTGACATCGA ATGTGTCCAC
AAAGAATCAG GCATCATCAT AGGAGTCACA GTTGCAGCCG TAGTCTTGAT TGTGGCTGTG
TTTGTTTGCA AGTCTTTACT GTGGAAGAAA GTCCTTCCTT ACCTGAAAGG CATCTGCTCA
GGTGGTGGTG GGGACCCTGA GCGTGTGGAC AGAAGCTCAC AACGACCTGG GGCTGAGGAC
AATGTCCTCA ATGAGATCGT GAGTATCTTG CAGCCCACCC AGGTCCCTGA GCAGGAAATG
GAAGTCCAGG AGCCAGCAGA GCCAACAGGT GTCAACATGT TGTCCCCCGG GGAGTCAGAG
CATCTGCTGG AACCGGCAGA AGCTGAAAGG TCTCAGAGGA GGAGGCTGCT GGTTCCAGCA
AATGAAGGTG ATCCCACTGA GACTCTGAGA CAGTGCTTCG ATGACTTTGC AGACTTGGTG
CCCTTTGACT CCTGGGAGCC GCTCATGAGG AAGTTGGGCC TCATGGACAA TGAGATAAAG
GTGGCTAAAG CTGAGGCAGC GGGCCACAGG GACACCTTGT ACACGATGCT GATAAAGTGG
GTCAACAAAA CCGGGCGAGA TGCCTCTGTC CACACCCTGC TGGATGCCTT GGAGACGCTG
GGAGAGAGAC TTGCCAAGCA GAAGATTGAG GACCACTTGT TGAGCTCTGG AAAGTTCATG
TATCTAGAAG GTAATGCAGA CTCTGCCATG TCCTAA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

book

Nuclear death receptor TRAIL-R2 inhibits maturation of let-7 and promotes proliferation of pancreatic and other tumor cells
Gastroenterology 146 (1), 278-290 (2014)
Haselmann V, Kurz A, Bertsch U, Hubner S, Olempska-Muller M, Fritsch J, Hasler R, Pickl A, Fritsche H, Annewanter F, Engler C, Fleig B, Bernt A, Roder C, Schmidt H, Gelhaus C, Hauser C, Egberts JH, Heneweer C, Rohde AM, Boger C, Knippschild U, Rocken C, Adam D, Walczak H, Schutze S, Janssen O, Wulczyn FG, Wajant H, Kalthoff H and Trauzold A.


book

Activated Cdc42-associated kinase 1 (Ack1) is required for tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) receptor recruitment to lipid rafts and induction of cell death
J. Biol. Chem. 288 (46), 32922-32931 (2013)
Linderoth E, Pilia G, Mahajan NP and Ferby I.


book

Azadirone, a limonoid tetranortriterpene, induces death receptors and sensitizes human cancer cells to tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) through a p53 protein-independent mechanism: evidence for the role of the ROS-ERK-CHOP-death receptor pathway
J. Biol. Chem. 288 (45), 32343-32356 (2013)
Gupta SC, Francis SK, Nair MS, Mo YY and Aggarwal BB.


book

Ibuprofen enhances TRAIL-induced apoptosis through DR5 upregulation
Oncol. Rep. 30 (5), 2379-2384 (2013)
Todo M, Horinaka M, Tomosugi M, Tanaka R, Ikawa H, Sowa Y, Ishikawa H, Fujiwara H, Otsuji E and Sakai T.


book

Noninvasive monitoring of pharmacodynamics and kinetics of a death receptor 5 antibody and its enhanced apoptosis induction in sequential application with doxorubicin
Neoplasia 15 (8), 863-874 (2013)
Weber TG, Poschinger T, Galban S, Rehemtulla A and Scheuer W.


book

TRAIL-R2: a novel apoptosis-mediating receptor for TRAIL
EMBO J. 16 (17), 5386-5397 (1997)
Walczak H, Degli-Esposti MA, Johnson RS, Smolak PJ, Waugh JY, Boiani N, Timour MS, Gerhart MJ, Schooley KA, Smith CA, Goodwin RG and Rauch CT.


book

TRICK2, a new alternatively spliced receptor that transduces the cytotoxic signal from TRAIL
Curr. Biol. 7 (9), 693-696 (1997)
Screaton GR, Mongkolsapaya J, Xu XN, Cowper AE, McMichael AJ and Bell JI.


book

Control of TRAIL-induced apoptosis by a family of signaling and decoy receptors
Science 277 (5327), 818-821 (1997)
Sheridan JP, Marsters SA, Pitti RM, Gurney A, Skubatch M, Baldwin D, Ramakrishnan L, Gray CL, Baker K, Wood WI, Goddard AD, Godowski P and Ashkenazi A.


book

An antagonist decoy receptor and a death domain-containing receptor for TRAIL
Science 277 (5327), 815-818 (1997)
Pan G, Ni J, Wei YF, Yu G, Gentz R and Dixit VM.


book

Identification and characterization of a new member of the TNF family that induces apoptosis
Immunity 3 (6), 673-682 (1995)
Wiley SR, Schooley K, Smolak PJ, Din WS, Huang CP, Nicholl JK, Sutherland GR, Smith TD, Rauch C and Smith CA.


 
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