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ACTN2 cDNA ORF clone, Homo sapiens (human)

Gene Symbol ACTN2
Entrez Gene ID 88
Full Name actinin, alpha 2
Synonyms CMD1AA, CMH23
General protein information
Preferred Names
alpha-actinin-2
Names
alpha-actinin-2
F-actin cross-linking protein
alpha-actinin skeletal muscle
Gene Type protein-coding
Organism Homo sapiens (human)
Genome

1

1q42-q43

Summary Alpha actinins belong to the spectrin gene superfamily which represents a diverse group of cytoskeletal proteins, including the alpha and beta spectrins and dystrophins. Alpha actinin is an actin-binding protein with multiple roles in different cell types. In nonmuscle cells, the cytoskeletal isoform is found along microfilament bundles and adherens-type junctions, where it is involved in binding actin to the membrane. In contrast, skeletal, cardiac, and smooth muscle isoforms are localized to the Z-disc and analogous dense bodies, where they help anchor the myofibrillar actin filaments. This gene encodes a muscle-specific, alpha actinin isoform that is expressed in both skeletal and cardiac muscles. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2013]. lac of sum
Disorder MIM:

102573

Disorder Html: Cardiomyopathy, dilated, 1AA, 612158 (3)

mRNA and Protein(s)

mRNA Protein Name
NM_001103 NP_001094 alpha-actinin-2 isoform 1
NM_001278344 NP_001265273 alpha-actinin-2 isoform 3
NM_001278343 NP_001265272 alpha-actinin-2 isoform 2



Homo sapiens (human) ACTN2 NP_001094.1
Pan troglodytes (chimpanzee) ACTN2 XP_001158729.2
Macaca mulatta (Rhesus monkey) ACTN2 XP_001097795.1
Canis lupus familiaris (dog) ACTN2 XP_856116.1
Bos taurus (cattle) ACTN2 NP_001029807.1
Mus musculus (house mouse) Actn2 NP_150371.4
Rattus norvegicus (Norway rat) Actn2 NP_001163796.1
Gallus gallus (chicken) ACTN2 NP_990654.1
Danio rerio (zebrafish) actn2 NP_001032662.1
Xenopus (Silurana) tropicalis (western clawed frog) actn2 NP_001005053.1


GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following ACTN2 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the ACTN2 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

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***CloneID RefSeq Accession Definition **Vector *Turnaround time Price (USD) Select
OHu22647
NM_001103 Homo sapiens actinin, alpha 2 (ACTN2), transcript variant 1, mRNA. pcDNA3.1+/C-(K)DYK or customized vector
in pcDNA3.1+/C-(K)DYK
$189.50-$265.30
$379.00
OHu22707 NM_001278344 Homo sapiens actinin, alpha 2 (ACTN2), transcript variant 3, mRNA. pcDNA3.1+/C-(K)DYK or customized vector 12-14 $391.30
$559.00
OHu23009 NM_001278343 Homo sapiens actinin, alpha 2 (ACTN2), transcript variant 2, mRNA. pcDNA3.1+/C-(K)DYK or customized vector 12-14 $475.30
$679.00

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.


CloneID OHu22647
Clone ID Related Accession (Same CDS sequence) NM_001103
Accession Version NM_001103.3 Documents for ORF clone product in dufault vector
Sequence Information ORF Nucleotide Sequence (Length: 2685bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags COA
ORF Insert Method CloneEZ® Seamless cloning technology
Insert Structure linear
Update Date 27-APR-2015
Organism Homo sapiens (human)
Product alpha-actinin-2 isoform 1
Comment REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AK315250.1, BC047901.2, AL359185.25 and BX103017.1. This sequence is a reference standard in the RefSeqGene project. On May 29, 2013 this sequence version replaced gi:161377421. Transcript Variant: This variant (1) encodes one of the longer isoforms (1) of this gene. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: M86406.1, BC047901.2 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1968968, SAMEA2144333 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
1501
1561
1621
1681
1741
1801
1861
1921
1981
2041
2101
2161
2221
2281
2341
2401
2461
2521
2581
2641
ATGAACCAGA TAGAGCCCGG CGTGCAGTAC AACTACGTGT ACGACGAGGA TGAGTACATG 
ATCCAGGAGG AGGAGTGGGA CCGCGACCTG CTCCTGGACC CAGCCTGGGA GAAGCAGCAG
AGGAAGACCT TCACTGCCTG GTGTAACTCC CACCTAAGGA AAGCCGGCAC CCAGATTGAG
AACATCGAGG AAGACTTCAG GAATGGCCTT AAGCTCATGC TGCTTTTGGA AGTCATCTCA
GGGGAAAGGC TGCCCAAACC TGACCGGGGA AAAATGCGGT TCCACAAAAT TGCTAATGTC
AACAAAGCTT TGGATTACAT AGCCAGCAAA GGGGTGAAAC TGGTGTCCAT CGGCGCTGAA
GAAATTGTTG ATGGCAATGT GAAAATGACC CTGGGTATGA TCTGGACCAT CATCCTTCGC
TTTGCTATTC AGGATATTTC GGTTGAAGAA ACATCTGCCA AAGAAGGTCT GCTGCTTTGG
TGTCAGAGGA AAACTGCTCC TTATAGAAAT GTGAACATTC AGAACTTCCA TACTAGCTGG
AAAGATGGCC TTGGACTCTG TGCCCTCATC CACCGACACC GGCCTGACCT CATTGACTAC
TCAAAGCTTA ACAAGGATGA CCCCATAGGA AATATTAACC TGGCCATGGA AATCGCTGAG
AAGCACCTGG ATATTCCTAA AATGTTGGAT GCTGAAGACA TCGTGAACAC CCCTAAACCC
GATGAAAGAG CCATCATGAC GTACGTCTCT TGCTTCTACC ACGCTTTTGC GGGCGCGGAG
CAGGCCGAGA CAGCGGCTAA CAGGATATGT AAGGTTCTTG CTGTGAATCA AGAGAATGAG
AGGCTGATGG AAGAATATGA GAGGCTAGCG AGTGAGCTTT TGGAATGGAT TCGTCGCACG
ATCCCCTGGC TGGAGAACCG GACTCCCGAG AAGACCATGC AAGCCATGCA GAAGAAGCTG
GAGGACTTCC GGGATTACCG CCGGAAGCAC AAGCCACCCA AGGTGCAGGA GAAATGCCAG
CTGGAGATCA ACTTCAACAC GCTGCAGACC AAGCTGCGGA TCAGCAACCG TCCTGCCTTC
ATGCCCTCCG AGGGCAAGAT GGTGTCGGAT ATTGCTGGTG CCTGGCAGAG GCTGGAGCAG
GCTGAGAAGG GTTACGAGGA GTGGTTGCTC AATGAGATTC GGAGACTGGA GCGCTTGGAA
CACCTGGCTG AGAAGTTCAG GCAGAAGGCC TCAACGCACG AGACTTGGGC TTATGGCAAA
GAGCAGATCT TGCTGCAGAA GGATTACGAG TCGGCGTCGC TGACAGAGGT GCGGGCTCTG
CTGCGGAAGC ACGAGGCGTT CGAGAGCGAC CTGGCAGCGC ACCAGGACCG CGTGGAGCAG
ATCGCAGCCA TCGCGCAGGA GCTCAATGAA CTGGACTATC ACGACGCTGT GAATGTCAAT
GATCGGTGCC AGAAAATTTG TGACCAGTGG GACCGACTGG GAACGCTTAC TCAGAAGAGG
AGAGAAGCCC TAGAGAGAAT GGAGAAATTG CTAGAAACCA TTGATCAGCT TCACCTGGAG
TTTGCCAAGA GGGCTGCTCC TTTCAACAAT TGGATGGAGG GCGCTATGGA GGATCTGCAA
GATATGTTCA TTGTCCACAG CATTGAGGAG ATCCAGAGTC TGATCACTGC GCATGAGCAG
TTCAAGGCCA CGCTGCCCGA GGCGGACGGA GAGCGGCAGT CCATCATGGC CATCCAGAAC
GAGGTGGAGA AGGTGATTCA GAGCTACAAC ATCAGAATCA GCTCAAGCAA CCCGTACAGC
ACTGTCACCA TGGATGAGCT CCGGACCAAG TGGGACAAGG TGAAGCAACT CGTGCCCATC
CGCGATCAAT CCCTGCAGGA GGAGCTGGCT CGCCAGCATG CTAACGAGCG TCTGAGGCGC
CAGTTTGCTG CCCAAGCCAA TGCCATTGGG CCCTGGATCC AGAACAAGAT GGAGGAGATT
GCCCGGAGCT CCATCCAGAT CACAGGAGCC CTGGAAGACC AGATGAACCA GCTGAAGCAG
TATGAGCACA ACATCATCAA CTATAAGAAC AACATCGACA AGCTGGAGGG AGACCATCAG
CTCATCCAGG AGGCCCTTGT CTTTGACAAC AAGCACACGA ACTACACGAT GGAGCACATT
CGTGTTGGAT GGGAGCTGCT GCTGACAACC ATCGCCAGAA CCATCAATGA GGTGGAGACT
CAGATCCTGA CGAGAGATGC GAAGGGCATC ACCCAGGAGC AGATGAATGA GTTCAGAGCC
TCCTTCAACC ACTTTGACAG GAGGAAGAAT GGCCTGATGG ATCATGAGGA TTTCAGAGCC
TGCCTGATTT CCATGGGTTA TGACCTGGGT GAAGCCGAAT TTGCCCGCAT TATGACCCTG
GTAGATCCCA ACGGGCAAGG CACCGTCACC TTCCAATCCT TCATCGACTT CATGACTAGA
GAGACGGCTG ACACCGACAC TGCCGAGCAG GTCATCGCCT CCTTCCGGAT CCTGGCTTCT
GATAAGCCAT ACATCCTGGC GGAGGAGCTG CGTCGGGAGC TGCCCCCGGA TCAGGCCCAG
TACTGCATCA AGAGGATGCC CGCCTACTCG GGCCCAGGCA GTGTGCCTGG TGCACTGGAT
TACGCTGCGT TCTCTTCCGC ACTCTACGGG GAGAGCGATC TGTGA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq NP_001094.1
CDS221..2905
Misc Feature(1)338..646(+)
Misc Feature(2)338..640(+)
Misc Feature(3)674..991(+)
Misc Feature(4)674..985(+)
Misc Feature(5)1061..1393(+)
Misc Feature(6)1061..1393(+)
Misc Feature(7)1421..1738(+)
Misc Feature(8)1424..2107(+)
Misc Feature(9)1739..1756(+)
Misc Feature(10)1766..2101(+)
Misc Feature(11)2129..2440(+)
Misc Feature(12)2129..2437(+)
Misc Feature(13)2489..2677(+)
Misc Feature(14)2513..2674(+)
Misc Feature(15)2516..2659(+)
Misc Feature(16)2690..2890(+)
Exon (1)1..346
Gene:ACTN2
Gene Synonym:
Exon (2)347..461
Gene:ACTN2
Gene Synonym:
Exon (3)462..581
Gene:ACTN2
Gene Synonym:
Exon (4)582..668
Gene:ACTN2
Gene Synonym:
Exon (5)669..756
Gene:ACTN2
Gene Synonym:
Exon (6)757..835
Gene:ACTN2
Gene Synonym:
Exon (7)836..917
Gene:ACTN2
Gene Synonym:
Exon (8)918..1003
Gene:ACTN2
Gene Synonym:
Exon (9)1004..1096
Gene:ACTN2
Gene Synonym:
Exon (10)1097..1327
Gene:ACTN2
Gene Synonym:
Exon (11)1328..1475
Gene:ACTN2
Gene Synonym:
Exon (12)1476..1626
Gene:ACTN2
Gene Synonym:
Exon (13)1627..1735
Gene:ACTN2
Gene Synonym:
Exon (14)1736..1876
Gene:ACTN2
Gene Synonym:
Exon (15)1877..2059
Gene:ACTN2
Gene Synonym:
Exon (16)2060..2194
Gene:ACTN2
Gene Synonym:
Exon (17)2195..2374
Gene:ACTN2
Gene Synonym:
Exon (18)2375..2521
Gene:ACTN2
Gene Synonym:
Exon (19)2522..2587
Gene:ACTN2
Gene Synonym:
Exon (20)2588..2746
Gene:ACTN2
Gene Synonym:
Exon (21)2747..4917
Gene:ACTN2
Gene Synonym:
Translation

Target ORF information:

RefSeq Version NM_001103
Organism Homo sapiens (human)
Definition Homo sapiens actinin, alpha 2 (ACTN2), transcript variant 1, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
NM_001103

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
1501
1561
1621
1681
1741
1801
1861
1921
1981
2041
2101
2161
2221
2281
2341
2401
2461
2521
2581
2641
ATGAACCAGA TAGAGCCCGG CGTGCAGTAC AACTACGTGT ACGACGAGGA TGAGTACATG 
ATCCAGGAGG AGGAGTGGGA CCGCGACCTG CTCCTGGACC CAGCCTGGGA GAAGCAGCAG
AGGAAGACCT TCACTGCCTG GTGTAACTCC CACCTAAGGA AAGCCGGCAC CCAGATTGAG
AACATCGAGG AAGACTTCAG GAATGGCCTT AAGCTCATGC TGCTTTTGGA AGTCATCTCA
GGGGAAAGGC TGCCCAAACC TGACCGGGGA AAAATGCGGT TCCACAAAAT TGCTAATGTC
AACAAAGCTT TGGATTACAT AGCCAGCAAA GGGGTGAAAC TGGTGTCCAT CGGCGCTGAA
GAAATTGTTG ATGGCAATGT GAAAATGACC CTGGGTATGA TCTGGACCAT CATCCTTCGC
TTTGCTATTC AGGATATTTC GGTTGAAGAA ACATCTGCCA AAGAAGGTCT GCTGCTTTGG
TGTCAGAGGA AAACTGCTCC TTATAGAAAT GTGAACATTC AGAACTTCCA TACTAGCTGG
AAAGATGGCC TTGGACTCTG TGCCCTCATC CACCGACACC GGCCTGACCT CATTGACTAC
TCAAAGCTTA ACAAGGATGA CCCCATAGGA AATATTAACC TGGCCATGGA AATCGCTGAG
AAGCACCTGG ATATTCCTAA AATGTTGGAT GCTGAAGACA TCGTGAACAC CCCTAAACCC
GATGAAAGAG CCATCATGAC GTACGTCTCT TGCTTCTACC ACGCTTTTGC GGGCGCGGAG
CAGGCCGAGA CAGCGGCTAA CAGGATATGT AAGGTTCTTG CTGTGAATCA AGAGAATGAG
AGGCTGATGG AAGAATATGA GAGGCTAGCG AGTGAGCTTT TGGAATGGAT TCGTCGCACG
ATCCCCTGGC TGGAGAACCG GACTCCCGAG AAGACCATGC AAGCCATGCA GAAGAAGCTG
GAGGACTTCC GGGATTACCG CCGGAAGCAC AAGCCACCCA AGGTGCAGGA GAAATGCCAG
CTGGAGATCA ACTTCAACAC GCTGCAGACC AAGCTGCGGA TCAGCAACCG TCCTGCCTTC
ATGCCCTCCG AGGGCAAGAT GGTGTCGGAT ATTGCTGGTG CCTGGCAGAG GCTGGAGCAG
GCTGAGAAGG GTTACGAGGA GTGGTTGCTC AATGAGATTC GGAGACTGGA GCGCTTGGAA
CACCTGGCTG AGAAGTTCAG GCAGAAGGCC TCAACGCACG AGACTTGGGC TTATGGCAAA
GAGCAGATCT TGCTGCAGAA GGATTACGAG TCGGCGTCGC TGACAGAGGT GCGGGCTCTG
CTGCGGAAGC ACGAGGCGTT CGAGAGCGAC CTGGCAGCGC ACCAGGACCG CGTGGAGCAG
ATCGCAGCCA TCGCGCAGGA GCTCAATGAA CTGGACTATC ACGACGCTGT GAATGTCAAT
GATCGGTGCC AGAAAATTTG TGACCAGTGG GACCGACTGG GAACGCTTAC TCAGAAGAGG
AGAGAAGCCC TAGAGAGAAT GGAGAAATTG CTAGAAACCA TTGATCAGCT TCACCTGGAG
TTTGCCAAGA GGGCTGCTCC TTTCAACAAT TGGATGGAGG GCGCTATGGA GGATCTGCAA
GATATGTTCA TTGTCCACAG CATTGAGGAG ATCCAGAGTC TGATCACTGC GCATGAGCAG
TTCAAGGCCA CGCTGCCCGA GGCGGACGGA GAGCGGCAGT CCATCATGGC CATCCAGAAC
GAGGTGGAGA AGGTGATTCA GAGCTACAAC ATCAGAATCA GCTCAAGCAA CCCGTACAGC
ACTGTCACCA TGGATGAGCT CCGGACCAAG TGGGACAAGG TGAAGCAACT CGTGCCCATC
CGCGATCAAT CCCTGCAGGA GGAGCTGGCT CGCCAGCATG CTAACGAGCG TCTGAGGCGC
CAGTTTGCTG CCCAAGCCAA TGCCATTGGG CCCTGGATCC AGAACAAGAT GGAGGAGATT
GCCCGGAGCT CCATCCAGAT CACAGGAGCC CTGGAAGACC AGATGAACCA GCTGAAGCAG
TATGAGCACA ACATCATCAA CTATAAGAAC AACATCGACA AGCTGGAGGG AGACCATCAG
CTCATCCAGG AGGCCCTTGT CTTTGACAAC AAGCACACGA ACTACACGAT GGAGCACATT
CGTGTTGGAT GGGAGCTGCT GCTGACAACC ATCGCCAGAA CCATCAATGA GGTGGAGACT
CAGATCCTGA CGAGAGATGC GAAGGGCATC ACCCAGGAGC AGATGAATGA GTTCAGAGCC
TCCTTCAACC ACTTTGACAG GAGGAAGAAT GGCCTGATGG ATCATGAGGA TTTCAGAGCC
TGCCTGATTT CCATGGGTTA TGACCTGGGT GAAGCCGAAT TTGCCCGCAT TATGACCCTG
GTAGATCCCA ACGGGCAAGG CACCGTCACC TTCCAATCCT TCATCGACTT CATGACTAGA
GAGACGGCTG ACACCGACAC TGCCGAGCAG GTCATCGCCT CCTTCCGGAT CCTGGCTTCT
GATAAGCCAT ACATCCTGGC GGAGGAGCTG CGTCGGGAGC TGCCCCCGGA TCAGGCCCAG
TACTGCATCA AGAGGATGCC CGCCTACTCG GGCCCAGGCA GTGTGCCTGG TGCACTGGAT
TACGCTGCGT TCTCTTCCGC ACTCTACGGG GAGAGCGATC TGTGA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OHu22707
Clone ID Related Accession (Same CDS sequence) NM_001278344
Accession Version NM_001278344.1 Documents for ORF clone product in dufault vector
Sequence Information ORF Nucleotide Sequence (Length: 2061bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ® Seamless cloning technology
Insert Structure linear
Update Date 27-APR-2015
Organism Homo sapiens (human)
Product alpha-actinin-2 isoform 3
Comment REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AK315250.1, AB209521.1, AL359185.25 and BX103017.1. Transcript Variant: This variant (3) contains two alternate internal exons compared to variant 1. These differences cause translation initiation at a downstream AUG and result in an isoform (3) with a shorter N-terminus, compared to isoform 1. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AB209521.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2151741 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
1501
1561
1621
1681
1741
1801
1861
1921
1981
2041
ATGACGTACG TCTCTTGCTT CTACCACGCT TTTGCGGGCG CGGAGCAGGT TAGACAAAGT 
CTTAAAGCAC ACTCAGCTCT GTGGAAGGAT CCCCCTCCAG AAAGTTCTAC ATGTTCATAT
CAGGAGATGA GGAGGTCTTC AGTGAATTCA AGTGCAATGG CCGAGACAGC GGCTAACAGG
ATATGTAAGG TTCTTGCTGT GAATCAAGAG AATGAGAGGC TGATGGAAGA ATATGAGAGG
CTAGCGAGTG AGCTTTTGGA ATGGATTCGT CGCACGATCC CCTGGCTGGA GAACCGGACT
CCCGAGAAGA CCATGCAAGC CATGCAGAAG AAGCTGGAGG ACTTCCGGGA TTACCGCCGG
AAGCACAAGC CACCCAAGGT GCAGGAGAAA TGCCAGCTGG AGATCAACTT CAACACGCTG
CAGACCAAGC TGCGGATCAG CAACCGTCCT GCCTTCATGC CCTCCGAGGG CAAGATGGTG
TCGGATATTG CTGGTGCCTG GCAGAGGCTG GAGCAGGCTG AGAAGGGTTA CGAGGAGTGG
TTGCTCAATG AGATTCGGAG ACTGGAGCGC TTGGAACACC TGGCTGAGAA GTTCAGGCAG
AAGGCCTCAA CGCACGAGAC TTGGGCTTAT GGCAAAGAGC AGATCTTGCT GCAGAAGGAT
TACGAGTCGG CGTCGCTGAC AGAGGTGCGG GCTCTGCTGC GGAAGCACGA GGCGTTCGAG
AGCGACCTGG CAGCGCACCA GGACCGCGTG GAGCAGATCG CAGCCATCGC GCAGGAGCTC
AATGAACTGG ACTATCACGA CGCTGTGAAT GTCAATGATC GGTGCCAGAA AATTTGTGAC
CAGTGGGACC GACTGGGAAC GCTTACTCAG AAGAGGAGAG AAGCCCTAGA GAGAATGGAG
AAATTGCTAG AAACCATTGA TCAGCTTCAC CTGGAGTTTG CCAAGAGGGC TGCTCCTTTC
AACAATTGGA TGGAGGGCGC TATGGAGGAT CTGCAAGATA TGTTCATTGT CCACAGCATT
GAGGAGATCC AGAGTCTGAT CACTGCGCAT GAGCAGTTCA AGGCCACGCT GCCCGAGGCG
GACGGAGAGC GGCAGTCCAT CATGGCCATC CAGAACGAGG TGGAGAAGGT GATTCAGAGC
TACAACATCA GAATCAGCTC AAGCAACCCG TACAGCACTG TCACCATGGA TGAGCTCCGG
ACCAAGTGGG ACAAGGTGAA GCAACTCGTG CCCATCCGCG ATCAATCCCT GCAGGAGGAG
CTGGCTCGCC AGCATGCTAA CGAGCGTCTG AGGCGCCAGT TTGCTGCCCA AGCCAATGCC
ATTGGGCCCT GGATCCAGAA CAAGATGGAG GAGATTGCCC GGAGCTCCAT CCAGATCACA
GGAGCCCTGG AAGACCAGAT GAACCAGCTG AAGCAGTATG AGCACAACAT CATCAACTAT
AAGAACAACA TCGACAAGCT GGAGGGAGAC CATCAGCTCA TCCAGGAGGC CCTTGTCTTT
GACAACAAGC ACACGAACTA CACGATGGAG CACATTCGTG TTGGATGGGA GCTGCTGCTG
ACAACCATCG CCAGAACCAT CAATGAGGTG GAGACTCAGA TCCTGACGAG AGATGCGAAG
GGCATCACCC AGGAGCAGAT GAATGAGTTC AGAGCCTCCT TCAACCACTT TGACAGGAGG
AAGAATGGCC TGATGGATCA TGAGGATTTC AGAGCCTGCC TGATTTCCAT GGGTTATGAC
CTGGGTGAAG CCGAATTTGC CCGCATTATG ACCCTGGTAG ATCCCAACGG GCAAGGCACC
GTCACCTTCC AATCCTTCAT CGACTTCATG ACTAGAGAGA CGGCTGACAC CGACACTGCC
GAGCAGGTCA TCGCCTCCTT CCGGATCCTG GCTTCTGATA AGCCATACAT CCTGGCGGAG
GAGCTGCGTC GGGAGCTGCC CCCGGATCAG GCCCAGTACT GCATCAAGAG GATGCCCGCC
TACTCGGGCC CAGGCAGTGT GCCTGGTGCA CTGGATTACG CTGCGTTCTC TTCCGCACTC
TACGGGGAGA GCGATCTGTG A

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq NP_001265273.1
CDS1042..3102
Misc Feature(1)943..945(+)
Misc Feature(2)1258..1590(+)
Misc Feature(3)1621..2304(+)
Misc Feature(4)1936..1953(+)
Misc Feature(5)2326..2634(+)
Misc Feature(6)2686..2874(+)
Misc Feature(7)2710..2871(+)
Misc Feature(8)2713..2856(+)
Misc Feature(9)2887..3087(+)
Exon (1)1..346
Gene:ACTN2
Gene Synonym:
Exon (2)347..461
Gene:ACTN2
Gene Synonym:
Exon (3)462..581
Gene:ACTN2
Gene Synonym:
Exon (4)582..668
Gene:ACTN2
Gene Synonym:
Exon (5)669..756
Gene:ACTN2
Gene Synonym:
Exon (6)757..835
Gene:ACTN2
Gene Synonym:
Exon (7)836..917
Gene:ACTN2
Gene Synonym:
Exon (8)918..1003
Gene:ACTN2
Gene Synonym:
Exon (9)1004..1089
Gene:ACTN2
Gene Synonym:
Exon (10)1090..1200
Gene:ACTN2
Gene Synonym:
Exon (11)1201..1293
Gene:ACTN2
Gene Synonym:
Exon (12)1294..1524
Gene:ACTN2
Gene Synonym:
Exon (13)1525..1672
Gene:ACTN2
Gene Synonym:
Exon (14)1673..1823
Gene:ACTN2
Gene Synonym:
Exon (15)1824..1932
Gene:ACTN2
Gene Synonym:
Exon (16)1933..2073
Gene:ACTN2
Gene Synonym:
Exon (17)2074..2256
Gene:ACTN2
Gene Synonym:
Exon (18)2257..2391
Gene:ACTN2
Gene Synonym:
Exon (19)2392..2571
Gene:ACTN2
Gene Synonym:
Exon (20)2572..2718
Gene:ACTN2
Gene Synonym:
Exon (21)2719..2784
Gene:ACTN2
Gene Synonym:
Exon (22)2785..2943
Gene:ACTN2
Gene Synonym:
Exon (23)2944..5114
Gene:ACTN2
Gene Synonym:
Translation

Target ORF information:

RefSeq Version NM_001278344
Organism Homo sapiens (human)
Definition Homo sapiens actinin, alpha 2 (ACTN2), transcript variant 3, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
NM_001278344

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
1501
1561
1621
1681
1741
1801
1861
1921
1981
2041
ATGACGTACG TCTCTTGCTT CTACCACGCT TTTGCGGGCG CGGAGCAGGT TAGACAAAGT 
CTTAAAGCAC ACTCAGCTCT GTGGAAGGAT CCCCCTCCAG AAAGTTCTAC ATGTTCATAT
CAGGAGATGA GGAGGTCTTC AGTGAATTCA AGTGCAATGG CCGAGACAGC GGCTAACAGG
ATATGTAAGG TTCTTGCTGT GAATCAAGAG AATGAGAGGC TGATGGAAGA ATATGAGAGG
CTAGCGAGTG AGCTTTTGGA ATGGATTCGT CGCACGATCC CCTGGCTGGA GAACCGGACT
CCCGAGAAGA CCATGCAAGC CATGCAGAAG AAGCTGGAGG ACTTCCGGGA TTACCGCCGG
AAGCACAAGC CACCCAAGGT GCAGGAGAAA TGCCAGCTGG AGATCAACTT CAACACGCTG
CAGACCAAGC TGCGGATCAG CAACCGTCCT GCCTTCATGC CCTCCGAGGG CAAGATGGTG
TCGGATATTG CTGGTGCCTG GCAGAGGCTG GAGCAGGCTG AGAAGGGTTA CGAGGAGTGG
TTGCTCAATG AGATTCGGAG ACTGGAGCGC TTGGAACACC TGGCTGAGAA GTTCAGGCAG
AAGGCCTCAA CGCACGAGAC TTGGGCTTAT GGCAAAGAGC AGATCTTGCT GCAGAAGGAT
TACGAGTCGG CGTCGCTGAC AGAGGTGCGG GCTCTGCTGC GGAAGCACGA GGCGTTCGAG
AGCGACCTGG CAGCGCACCA GGACCGCGTG GAGCAGATCG CAGCCATCGC GCAGGAGCTC
AATGAACTGG ACTATCACGA CGCTGTGAAT GTCAATGATC GGTGCCAGAA AATTTGTGAC
CAGTGGGACC GACTGGGAAC GCTTACTCAG AAGAGGAGAG AAGCCCTAGA GAGAATGGAG
AAATTGCTAG AAACCATTGA TCAGCTTCAC CTGGAGTTTG CCAAGAGGGC TGCTCCTTTC
AACAATTGGA TGGAGGGCGC TATGGAGGAT CTGCAAGATA TGTTCATTGT CCACAGCATT
GAGGAGATCC AGAGTCTGAT CACTGCGCAT GAGCAGTTCA AGGCCACGCT GCCCGAGGCG
GACGGAGAGC GGCAGTCCAT CATGGCCATC CAGAACGAGG TGGAGAAGGT GATTCAGAGC
TACAACATCA GAATCAGCTC AAGCAACCCG TACAGCACTG TCACCATGGA TGAGCTCCGG
ACCAAGTGGG ACAAGGTGAA GCAACTCGTG CCCATCCGCG ATCAATCCCT GCAGGAGGAG
CTGGCTCGCC AGCATGCTAA CGAGCGTCTG AGGCGCCAGT TTGCTGCCCA AGCCAATGCC
ATTGGGCCCT GGATCCAGAA CAAGATGGAG GAGATTGCCC GGAGCTCCAT CCAGATCACA
GGAGCCCTGG AAGACCAGAT GAACCAGCTG AAGCAGTATG AGCACAACAT CATCAACTAT
AAGAACAACA TCGACAAGCT GGAGGGAGAC CATCAGCTCA TCCAGGAGGC CCTTGTCTTT
GACAACAAGC ACACGAACTA CACGATGGAG CACATTCGTG TTGGATGGGA GCTGCTGCTG
ACAACCATCG CCAGAACCAT CAATGAGGTG GAGACTCAGA TCCTGACGAG AGATGCGAAG
GGCATCACCC AGGAGCAGAT GAATGAGTTC AGAGCCTCCT TCAACCACTT TGACAGGAGG
AAGAATGGCC TGATGGATCA TGAGGATTTC AGAGCCTGCC TGATTTCCAT GGGTTATGAC
CTGGGTGAAG CCGAATTTGC CCGCATTATG ACCCTGGTAG ATCCCAACGG GCAAGGCACC
GTCACCTTCC AATCCTTCAT CGACTTCATG ACTAGAGAGA CGGCTGACAC CGACACTGCC
GAGCAGGTCA TCGCCTCCTT CCGGATCCTG GCTTCTGATA AGCCATACAT CCTGGCGGAG
GAGCTGCGTC GGGAGCTGCC CCCGGATCAG GCCCAGTACT GCATCAAGAG GATGCCCGCC
TACTCGGGCC CAGGCAGTGT GCCTGGTGCA CTGGATTACG CTGCGTTCTC TTCCGCACTC
TACGGGGAGA GCGATCTGTG A

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OHu23009
Clone ID Related Accession (Same CDS sequence) NM_001278343
Accession Version NM_001278343.1 Documents for ORF clone product in dufault vector
Sequence Information ORF Nucleotide Sequence (Length: 2685bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ® Seamless cloning technology
Insert Structure linear
Update Date 27-APR-2015
Organism Homo sapiens (human)
Product alpha-actinin-2 isoform 2
Comment REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AK315250.1, AL359185.25 and BX103017.1. Transcript Variant: This variant (2) lacks an alternate internal coding exon and contains another compared to variant 1. The resulting isoform (2) has a few internal differences but is the same length as isoform 1. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AK315250.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2144333, SAMEA2145743 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
1501
1561
1621
1681
1741
1801
1861
1921
1981
2041
2101
2161
2221
2281
2341
2401
2461
2521
2581
2641
ATGAACCAGA TAGAGCCCGG CGTGCAGTAC AACTACGTGT ACGACGAGGA TGAGTACATG 
ATCCAGGAGG AGGAGTGGGA CCGCGACCTG CTCCTGGACC CAGCCTGGGA GAAGCAGCAG
AGGAAGACCT TCACTGCCTG GTGTAACTCC CACCTAAGGA AAGCCGGCAC CCAGATTGAG
AACATCGAGG AAGACTTCAG GAATGGCCTT AAGCTCATGC TGCTTTTGGA AGTCATCTCA
GGGGAAAGGC TGCCCAAACC TGACCGGGGA AAAATGCGGT TCCACAAAAT TGCTAATGTC
AACAAAGCTT TGGATTACAT AGCCAGCAAA GGGGTGAAAC TGGTGTCCAT CGGCGCTGAA
GAAATTGTTG ATGGCAATGT GAAAATGACC CTGGGTATGA TCTGGACCAT CATCCTTCGC
TTTGCTATTC AGGATATTTC GGTTGAAGAA ACATCTGCCA AAGAAGGTCT GCTGCTTTGG
TGTCAGAGGA AAACTGCTCC TTATAGAAAT GTGAACATTC AGAACTTCCA TACTAGCTGG
AAAGATGGCC TTGGACTCTG TGCCCTCATC CACCGACACC GGCCTGACCT CATTGACTAC
TCAAAGCTTA ACAAGGATGA CCCCATAGGA AATATTAACC TGGCCATGGA AATCGCTGAG
AAGCACCTGG ATATTCCTAA AATGTTGGAT GCTGAAGATT TAGTATACAC TGCCAGACCC
GATGAAAGAG CCATAATGAC TTATGTTTCC TGTTACTATC ATGCTTTTGC TGGTGCACAG
AAGGCCGAGA CAGCGGCTAA CAGGATATGT AAGGTTCTTG CTGTGAATCA AGAGAATGAG
AGGCTGATGG AAGAATATGA GAGGCTAGCG AGTGAGCTTT TGGAATGGAT TCGTCGCACG
ATCCCCTGGC TGGAGAACCG GACTCCCGAG AAGACCATGC AAGCCATGCA GAAGAAGCTG
GAGGACTTCC GGGATTACCG CCGGAAGCAC AAGCCACCCA AGGTGCAGGA GAAATGCCAG
CTGGAGATCA ACTTCAACAC GCTGCAGACC AAGCTGCGGA TCAGCAACCG TCCTGCCTTC
ATGCCCTCCG AGGGCAAGAT GGTGTCGGAT ATTGCTGGTG CCTGGCAGAG GCTGGAGCAG
GCTGAGAAGG GTTACGAGGA GTGGTTGCTC AATGAGATTC GGAGACTGGA GCGCTTGGAA
CACCTGGCTG AGAAGTTCAG GCAGAAGGCC TCAACGCACG AGACTTGGGC TTATGGCAAA
GAGCAGATCT TGCTGCAGAA GGATTACGAG TCGGCGTCGC TGACAGAGGT GCGGGCTCTG
CTGCGGAAGC ACGAGGCGTT CGAGAGCGAC CTGGCAGCGC ACCAGGACCG CGTGGAGCAG
ATCGCAGCCA TCGCGCAGGA GCTCAATGAA CTGGACTATC ACGACGCTGT GAATGTCAAT
GATCGGTGCC AGAAAATTTG TGACCAGTGG GACCGACTGG GAACGCTTAC TCAGAAGAGG
AGAGAAGCCC TAGAGAGAAT GGAGAAATTG CTAGAAACCA TTGATCAGCT TCACCTGGAG
TTTGCCAAGA GGGCTGCTCC TTTCAACAAT TGGATGGAGG GCGCTATGGA GGATCTGCAA
GATATGTTCA TTGTCCACAG CATTGAGGAG ATCCAGAGTC TGATCACTGC GCATGAGCAG
TTCAAGGCCA CGCTGCCCGA GGCGGACGGA GAGCGGCAGT CCATCATGGC CATCCAGAAC
GAGGTGGAGA AGGTGATTCA GAGCTACAAC ATCAGAATCA GCTCAAGCAA CCCGTACAGC
ACTGTCACCA TGGATGAGCT CCGGACCAAG TGGGACAAGG TGAAGCAACT CGTGCCCATC
CGCGATCAAT CCCTGCAGGA GGAGCTGGCT CGCCAGCATG CTAACGAGCG TCTGAGGCGC
CAGTTTGCTG CCCAAGCCAA TGCCATTGGG CCCTGGATCC AGAACAAGAT GGAGGAGATT
GCCCGGAGCT CCATCCAGAT CACAGGAGCC CTGGAAGACC AGATGAACCA GCTGAAGCAG
TATGAGCACA ACATCATCAA CTATAAGAAC AACATCGACA AGCTGGAGGG AGACCATCAG
CTCATCCAGG AGGCCCTTGT CTTTGACAAC AAGCACACGA ACTACACGAT GGAGCACATT
CGTGTTGGAT GGGAGCTGCT GCTGACAACC ATCGCCAGAA CCATCAATGA GGTGGAGACT
CAGATCCTGA CGAGAGATGC GAAGGGCATC ACCCAGGAGC AGATGAATGA GTTCAGAGCC
TCCTTCAACC ACTTTGACAG GAGGAAGAAT GGCCTGATGG ATCATGAGGA TTTCAGAGCC
TGCCTGATTT CCATGGGTTA TGACCTGGGT GAAGCCGAAT TTGCCCGCAT TATGACCCTG
GTAGATCCCA ACGGGCAAGG CACCGTCACC TTCCAATCCT TCATCGACTT CATGACTAGA
GAGACGGCTG ACACCGACAC TGCCGAGCAG GTCATCGCCT CCTTCCGGAT CCTGGCTTCT
GATAAGCCAT ACATCCTGGC GGAGGAGCTG CGTCGGGAGC TGCCCCCGGA TCAGGCCCAG
TACTGCATCA AGAGGATGCC CGCCTACTCG GGCCCAGGCA GTGTGCCTGG TGCACTGGAT
TACGCTGCGT TCTCTTCCGC ACTCTACGGG GAGAGCGATC TGTGA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq NP_001265272.1
CDS221..2905
Misc Feature(1)338..646(+)
Misc Feature(2)338..640(+)
Misc Feature(3)674..991(+)
Misc Feature(4)674..985(+)
Misc Feature(5)1061..1393(+)
Misc Feature(6)1061..1393(+)
Misc Feature(7)1421..1738(+)
Misc Feature(8)1424..2107(+)
Misc Feature(9)1739..1756(+)
Misc Feature(10)1766..2101(+)
Misc Feature(11)2129..2440(+)
Misc Feature(12)2129..2437(+)
Misc Feature(13)2489..2677(+)
Misc Feature(14)2513..2674(+)
Misc Feature(15)2516..2659(+)
Misc Feature(16)2690..2890(+)
Exon (1)1..346
Gene:ACTN2
Gene Synonym:
Exon (2)347..461
Gene:ACTN2
Gene Synonym:
Exon (3)462..581
Gene:ACTN2
Gene Synonym:
Exon (4)582..668
Gene:ACTN2
Gene Synonym:
Exon (5)669..756
Gene:ACTN2
Gene Synonym:
Exon (6)757..835
Gene:ACTN2
Gene Synonym:
Exon (7)836..917
Gene:ACTN2
Gene Synonym:
Exon (8)918..1003
Gene:ACTN2
Gene Synonym:
Exon (9)1004..1096
Gene:ACTN2
Gene Synonym:
Exon (10)1097..1327
Gene:ACTN2
Gene Synonym:
Exon (11)1328..1475
Gene:ACTN2
Gene Synonym:
Exon (12)1476..1626
Gene:ACTN2
Gene Synonym:
Exon (13)1627..1735
Gene:ACTN2
Gene Synonym:
Exon (14)1736..1876
Gene:ACTN2
Gene Synonym:
Exon (15)1877..2059
Gene:ACTN2
Gene Synonym:
Exon (16)2060..2194
Gene:ACTN2
Gene Synonym:
Exon (17)2195..2374
Gene:ACTN2
Gene Synonym:
Exon (18)2375..2521
Gene:ACTN2
Gene Synonym:
Exon (19)2522..2587
Gene:ACTN2
Gene Synonym:
Exon (20)2588..2746
Gene:ACTN2
Gene Synonym:
Exon (21)2747..4917
Gene:ACTN2
Gene Synonym:
Translation

Target ORF information:

RefSeq Version NM_001278343
Organism Homo sapiens (human)
Definition Homo sapiens actinin, alpha 2 (ACTN2), transcript variant 2, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
NM_001278343

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
1501
1561
1621
1681
1741
1801
1861
1921
1981
2041
2101
2161
2221
2281
2341
2401
2461
2521
2581
2641
ATGAACCAGA TAGAGCCCGG CGTGCAGTAC AACTACGTGT ACGACGAGGA TGAGTACATG 
ATCCAGGAGG AGGAGTGGGA CCGCGACCTG CTCCTGGACC CAGCCTGGGA GAAGCAGCAG
AGGAAGACCT TCACTGCCTG GTGTAACTCC CACCTAAGGA AAGCCGGCAC CCAGATTGAG
AACATCGAGG AAGACTTCAG GAATGGCCTT AAGCTCATGC TGCTTTTGGA AGTCATCTCA
GGGGAAAGGC TGCCCAAACC TGACCGGGGA AAAATGCGGT TCCACAAAAT TGCTAATGTC
AACAAAGCTT TGGATTACAT AGCCAGCAAA GGGGTGAAAC TGGTGTCCAT CGGCGCTGAA
GAAATTGTTG ATGGCAATGT GAAAATGACC CTGGGTATGA TCTGGACCAT CATCCTTCGC
TTTGCTATTC AGGATATTTC GGTTGAAGAA ACATCTGCCA AAGAAGGTCT GCTGCTTTGG
TGTCAGAGGA AAACTGCTCC TTATAGAAAT GTGAACATTC AGAACTTCCA TACTAGCTGG
AAAGATGGCC TTGGACTCTG TGCCCTCATC CACCGACACC GGCCTGACCT CATTGACTAC
TCAAAGCTTA ACAAGGATGA CCCCATAGGA AATATTAACC TGGCCATGGA AATCGCTGAG
AAGCACCTGG ATATTCCTAA AATGTTGGAT GCTGAAGATT TAGTATACAC TGCCAGACCC
GATGAAAGAG CCATAATGAC TTATGTTTCC TGTTACTATC ATGCTTTTGC TGGTGCACAG
AAGGCCGAGA CAGCGGCTAA CAGGATATGT AAGGTTCTTG CTGTGAATCA AGAGAATGAG
AGGCTGATGG AAGAATATGA GAGGCTAGCG AGTGAGCTTT TGGAATGGAT TCGTCGCACG
ATCCCCTGGC TGGAGAACCG GACTCCCGAG AAGACCATGC AAGCCATGCA GAAGAAGCTG
GAGGACTTCC GGGATTACCG CCGGAAGCAC AAGCCACCCA AGGTGCAGGA GAAATGCCAG
CTGGAGATCA ACTTCAACAC GCTGCAGACC AAGCTGCGGA TCAGCAACCG TCCTGCCTTC
ATGCCCTCCG AGGGCAAGAT GGTGTCGGAT ATTGCTGGTG CCTGGCAGAG GCTGGAGCAG
GCTGAGAAGG GTTACGAGGA GTGGTTGCTC AATGAGATTC GGAGACTGGA GCGCTTGGAA
CACCTGGCTG AGAAGTTCAG GCAGAAGGCC TCAACGCACG AGACTTGGGC TTATGGCAAA
GAGCAGATCT TGCTGCAGAA GGATTACGAG TCGGCGTCGC TGACAGAGGT GCGGGCTCTG
CTGCGGAAGC ACGAGGCGTT CGAGAGCGAC CTGGCAGCGC ACCAGGACCG CGTGGAGCAG
ATCGCAGCCA TCGCGCAGGA GCTCAATGAA CTGGACTATC ACGACGCTGT GAATGTCAAT
GATCGGTGCC AGAAAATTTG TGACCAGTGG GACCGACTGG GAACGCTTAC TCAGAAGAGG
AGAGAAGCCC TAGAGAGAAT GGAGAAATTG CTAGAAACCA TTGATCAGCT TCACCTGGAG
TTTGCCAAGA GGGCTGCTCC TTTCAACAAT TGGATGGAGG GCGCTATGGA GGATCTGCAA
GATATGTTCA TTGTCCACAG CATTGAGGAG ATCCAGAGTC TGATCACTGC GCATGAGCAG
TTCAAGGCCA CGCTGCCCGA GGCGGACGGA GAGCGGCAGT CCATCATGGC CATCCAGAAC
GAGGTGGAGA AGGTGATTCA GAGCTACAAC ATCAGAATCA GCTCAAGCAA CCCGTACAGC
ACTGTCACCA TGGATGAGCT CCGGACCAAG TGGGACAAGG TGAAGCAACT CGTGCCCATC
CGCGATCAAT CCCTGCAGGA GGAGCTGGCT CGCCAGCATG CTAACGAGCG TCTGAGGCGC
CAGTTTGCTG CCCAAGCCAA TGCCATTGGG CCCTGGATCC AGAACAAGAT GGAGGAGATT
GCCCGGAGCT CCATCCAGAT CACAGGAGCC CTGGAAGACC AGATGAACCA GCTGAAGCAG
TATGAGCACA ACATCATCAA CTATAAGAAC AACATCGACA AGCTGGAGGG AGACCATCAG
CTCATCCAGG AGGCCCTTGT CTTTGACAAC AAGCACACGA ACTACACGAT GGAGCACATT
CGTGTTGGAT GGGAGCTGCT GCTGACAACC ATCGCCAGAA CCATCAATGA GGTGGAGACT
CAGATCCTGA CGAGAGATGC GAAGGGCATC ACCCAGGAGC AGATGAATGA GTTCAGAGCC
TCCTTCAACC ACTTTGACAG GAGGAAGAAT GGCCTGATGG ATCATGAGGA TTTCAGAGCC
TGCCTGATTT CCATGGGTTA TGACCTGGGT GAAGCCGAAT TTGCCCGCAT TATGACCCTG
GTAGATCCCA ACGGGCAAGG CACCGTCACC TTCCAATCCT TCATCGACTT CATGACTAGA
GAGACGGCTG ACACCGACAC TGCCGAGCAG GTCATCGCCT CCTTCCGGAT CCTGGCTTCT
GATAAGCCAT ACATCCTGGC GGAGGAGCTG CGTCGGGAGC TGCCCCCGGA TCAGGCCCAG
TACTGCATCA AGAGGATGCC CGCCTACTCG GGCCCAGGCA GTGTGCCTGG TGCACTGGAT
TACGCTGCGT TCTCTTCCGC ACTCTACGGG GAGAGCGATC TGTGA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

book

The structure and regulation of human muscle alpha-actinin
Cell 159 (6), 1447-1460 (2014)
Ribeiro Ede A Jr, Pinotsis N, Ghisleni A, Salmazo A, Konarev PV, Kostan J, Sjoblom B, Schreiner C, Polyansky AA, Gkougkoulia EA, Holt MR, Aachmann FL, Zagrovic B, Bordignon E, Pirker KF, Svergun DI, Gautel M and Djinovic-Carugo K.


book

Genome-wide association study of chronic periodontitis in a general German population
J. Clin. Periodontol. 40 (11), 977-985 (2013)
Teumer A, Holtfreter B, Volker U, Petersmann A, Nauck M, Biffar R, Volzke H, Kroemer HK, Meisel P, Homuth G and Kocher T.


book

Proteomic analysis of podocyte exosome-enriched fraction from normal human urine
J Proteomics 82, 193-229 (2013)
Prunotto M, Farina A, Lane L, Pernin A, Schifferli J, Hochstrasser DF, Lescuyer P and Moll S.


book

Substrate-selective and calcium-independent activation of CaMKII by alpha-actinin
J. Biol. Chem. 287 (19), 15275-15283 (2012)
Jalan-Sakrikar N, Bartlett RK, Baucum AJ 2nd and Colbran RJ.


book

Activation of human neutrophils induces an interaction between the integrin beta 2-subunit (CD18) and the actin binding protein alpha-actinin
J. Immunol. 151 (7), 3795-3807 (1993)
Pavalko FM and LaRoche SM.


book

Hypertrophic Cardiomyopathy Overview
(in) Pagon RA, Adam MP, Ardinger HH, Wallace SE, Amemiya A, Bean LJH, Bird TD, Dolan CR, Fong CT, Smith RJH and Stephens K (Eds.); GENEREVIEWS(R); (1993)
Cirino,A.L. and Ho,C.


book

Dilated Cardiomyopathy Overview
(in) Pagon RA, Adam MP, Ardinger HH, Wallace SE, Amemiya A, Bean LJH, Bird TD, Dolan CR, Fong CT, Smith RJH and Stephens K (Eds.); GENEREVIEWS(R); (1993)
Hershberger,R.E. and Morales,A.


book

A (CA)n repeat polymorphism for the human skeletal muscle alpha-actinin gene ACTN2 and its localization on the linkage map of chromosome 1
Genomics 13 (4), 1314-1315 (1992)
Beggs AH, Phillips HA, Kozman H, Mulley JC, Wilton SD, Kunkel LM and Laing NG.


book

Cloning and characterization of two human skeletal muscle alpha-actinin genes located on chromosomes 1 and 11
J. Biol. Chem. 267 (13), 9281-9288 (1992)
Beggs AH, Byers TJ, Knoll JH, Boyce FM, Bruns GA and Kunkel LM.


book

Alpha-actinin and vinculin in human neutrophils: reorganization during adhesion and relation to the actin network
J. Cell. Sci. 101 (PT 2), 403-414 (1992)
Yuruker B and Niggli V.


 
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