×

AP1M1 cDNA ORF clone, Homo sapiens(Human)

Gene Symbol AP1M1
Entrez Gene ID 8907
Full Name adaptor related protein complex 1 mu 1 subunit
Synonyms AP47,CLAPM2,CLTNM,MU-1A
General protein information
Preferred Names

adaptor related protein complex 1 mu 1 subunit

Names

AP-1 complex subunit mu-1
AP-mu chain family member mu1A
HA1 47 kDa subunit
adapter-related protein complex 1 subunit mu-1
adaptor protein complex AP-1 mu-1 subunit
adaptor protein complex AP-1 subunit mu-1
adaptor-related protein complex 1 subunit mu-1
clathrin adaptor protein AP47
clathrin assembly protein complex 1 medium chain 1
clathrin assembly protein complex 1 mu-1 medium chain 1
clathrin assembly protein complex 1, medium chain
clathrin assembly protein complex AP1, mu subunit
clathrin coat assembly protein AP47
clathrin coat-associated protein AP47
golgi adaptor AP-1 47 kDa protein
golgi adaptor HA1/AP1 adaptin mu-1 subunit
mu-adaptin 1
mu1A-adaptin

Gene Type protein-coding
Organism Homo sapiens(Human)
Genome

19

19p13.11

Summary The protein encoded by this gene is the medium chain of the trans-Golgi network clathrin-associated protein complex AP-1. The other components of this complex are beta-prime-adaptin, gamma-adaptin, and the small chain AP1S1. This complex is located at the Golgi vesicle and links clathrin to receptors in coated vesicles. These vesicles are involved in endocytosis and Golgi processing. Alternatively spliced transcript variants encoding distinct protein isoforms have been found for this gene. [provided by RefSeq, Jul 2008].
Disorder MIM:

603535


mRNA and Protein(s)

mRNA Protein Name
XM_017027420.1 XP_016882909.1 AP-1 complex subunit mu-1 isoform X1
XM_017027421.1 XP_016882910.1 AP-1 complex subunit mu-1 isoform X2
NM_032493.3 NP_115882.1 AP-1 complex subunit mu-1 isoform 2
NM_001130524.1 NP_001123996.1 AP-1 complex subunit mu-1 isoform 1



Canis lupus familiaris (dog) AP1M1 XP_003432952.1
Caenorhabditis elegans (roundworm) unc-101 NP_001040675.1
Arabidopsis thaliana (thale cress) HAP13 NP_176277.1
Oryza sativa (rice) Os01g0703600 NP_001044001.1
Bos taurus (cattle) AP1M1 NP_001039349.2
Magnaporthe oryzae (rice blast fungus) MGG_10633 XP_003710726.1
Arabidopsis thaliana (thale cress) AT1G10730 NP_172543.1
Drosophila melanogaster (fruit fly) AP-47 NP_649906.1
Anopheles gambiae (African malaria mosquito) AgaP_AGAP011374 XP_317947.4
Neurospora crassa NCU09688 XP_960620.2
Xenopus tropicalis (tropical clawed frog) ap1m1 NP_989033.1
Homo sapiens (human) AP1M1 NP_001123996.1
Danio rerio (zebrafish) ap1m3 NP_001107913.1
Saccharomyces cerevisiae (baker's yeast) APM1 NP_015064.1
Kluyveromyces lactis KLLA0D14311g XP_453698.1
Eremothecium gossypii AGOS_ADL017C NP_984080.1
Schizosaccharomyces pombe (fission yeast) apm1 NP_595781.1
Pan troglodytes (chimpanzee) AP1M1 NP_001233313.1
Mus musculus (house mouse) Ap1m1 NP_031482.1
Rattus norvegicus (Norway rat) Ap1m1 NP_001037704.1
Gallus gallus (chicken) AP1M1 NP_001007887.1
Oryza sativa (rice) Os05g0543100 NP_001056201.1
Macaca mulatta (rhesus monkey) AP1M1 XP_001112653.1


Related articles in PubMed

Basolateral sorting of the Mg²⁺ transporter CNNM4 requires interaction with AP-1A and AP-1B.
Hirata Y, Funato Y, Miki H
Biochemical and biophysical research communications455(3-4)184-9(2014 Dec)

Adaptor protein 1 promotes cross-presentation through the same tyrosine signal in major histocompatibility complex class I as that targeted by HIV-1.
Kulpa DA, Del Cid N, Peterson KA, Collins KL
Journal of virology87(14)8085-98(2013 Jul)

The AP-1 complex regulates intracellular localization of insulin receptor substrate 1, which is required for insulin-like growth factor I-dependent cell proliferation.
Yoneyama Y, Matsuo M, Take K, Kabuta T, Chida K, Hakuno F, Takahashi S
Molecular and cellular biology33(10)1991-2003(2013 May)

A noncanonical mu-1A-binding motif in the N terminus of HIV-1 Nef determines its ability to downregulate major histocompatibility complex class I in T lymphocytes.
Iijima S, Lee YJ, Ode H, Arold ST, Kimura N, Yokoyama M, Sato H, Tanaka Y, Strebel K, Akari H
Journal of virology86(7)3944-51(2012 Apr)

Human kidney anion exchanger 1 interacts with adaptor-related protein complex 1 μ1A (AP-1 mu1A).
Sawasdee N, Junking M, Ngaojanlar P, Sukomon N, Ungsupravate D, Limjindaporn T, Akkarapatumwong V, Noisakran S, Yenchitsomanus PT
Biochemical and biophysical research communications401(1)85-91(2010 Oct)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

CNNM4 is sorted to the basolateral membrane by the complementary function of AP-1A and AP-1B
Title: Basolateral sorting of the Mg²⁺ transporter CNNM4 requires interaction with AP-1A and AP-1B.

Adaptor protein 1 promotes cross-presentation through the same tyrosine signal in major histocompatibility complex class I as that targeted by HIV-1.
Title: Adaptor protein 1 promotes cross-presentation through the same tyrosine signal in major histocompatibility complex class I as that targeted by HIV-1.

IRS-1 associates with mu1A of the ubiquitously expressed AP-1 complex through three protein interaction motifs.
Title: The AP-1 complex regulates intracellular localization of insulin receptor substrate 1, which is required for insulin-like growth factor I-dependent cell proliferation.

Mu1A binding to the N terminus of HIV-1 Nef determines its ability to downregulate major histocompatibility complex class I in T lymphocytes.
Title: A noncanonical mu-1A-binding motif in the N terminus of HIV-1 Nef determines its ability to downregulate major histocompatibility complex class I in T lymphocytes.

AP-1 mu1A is involved in the kAE1 trafficking of kidney alpha-intercalated cells
Title: Human kidney anion exchanger 1 interacts with adaptor-related protein complex 1 μ1A (AP-1 mu1A).

The following AP1M1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the AP1M1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

Online Only Promotion

Up to 50% OFF! Starting
from $49/clone

***CloneID RefSeq Accession Definition **Vector *Turnaround time Price (USD) Select
OHu07051 NM_001130524.1
Latest version!
Homo sapiens adaptor related protein complex 1 mu 1 subunit (AP1M1), transcript variant 1, mRNA. pcDNA3.1+/C-(K)DYK or customized vector 7-9 $223.30
$319.00
OHu30674 NM_032493.3
Latest version!
Homo sapiens adaptor related protein complex 1 mu 1 subunit (AP1M1), transcript variant 2, mRNA. pcDNA3.1+/C-(K)DYK or customized vector 7-9 $223.30
$319.00
OHu62299 XM_017027421.1
Latest version!
Homo sapiens adaptor related protein complex 1 mu 1 subunit (AP1M1), transcript variant X2, mRNA. pcDNA3.1+/C-(K)DYK or customized vector 7-9 $223.30
$319.00
OHu88790 XM_017027420.1
Latest version!
Homo sapiens adaptor related protein complex 1 mu 1 subunit (AP1M1), transcript variant X1, mRNA. pcDNA3.1+/C-(K)DYK or customized vector 9-11 $223.30
$319.00

ORF Online Only Promotion

Next-day Shipping ORF Clones ( in default vector with tag)
1 Clone 30% OFF
2-4 Clone 40% OFF
5 or more Clone 50% OFF
All Other ORF Clones
30% OFF

*Business Day

** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.


CloneID OHu07051
Clone ID Related Accession (Same CDS sequence) NM_001130524.1
Accession Version NM_001130524.1 Latest version! Documents for ORF clone product in dufault vector
Sequence Information ORF Nucleotide Sequence (Length: 1308bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ® Seamless cloning technology
Insert Structure linear
Update Date 2017-05-04
Organism Homo sapiens(Human)
Product AP-1 complex subunit mu-1 isoform 1
Comment REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from DC386056.1, DQ059565.1, AB209808.1, BU729646.1 and BQ014582.1. Transcript Variant: This variant (1) encodes the longer isoform (1). Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AB209808.1, SRR1803616.245282.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA2142853 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
ATGTCCGCCA GCGCCGTCTA CGTGCTGGAC CTGAAGGGCA AGGTGCTCAT CTGCCGGAAC 
TACCGTGGCG ACGTGGACAT GTCAGAGGTG GAGCACTTCA TGCCCATCCT GATGGAGAAG
GAGGAGGAGG GGATGCTGTC GCCCATCCTG GCCCACGGGG GGGTCCGTTT CATGTGGATC
AAACACAACA ACCTGTATCT GGTTGCCACA TCCAAGAAGA ACGCGTGCGT GTCGCTGGTC
TTTTCTTTCC TCTATAAGGT GGTGCAGGTG TTTTCCGAGT ACTTCAAGGA GCTGGAGGAG
GAGAGCATCC GGGACAACTT TGTTATCATC TACGAGCTGC TGGACGAGCT CATGGACTTC
GGCTACCCCC AGACCACCGA CAGCAAGATC CTGCAGGAGT ACATCACTCA GGAAGGCCAC
AAGCTGGAAA CAGGGGCCCC GCGGCCACCA GCCACCGTCA CCAACGCGGT GTCCTGGCGG
TCCGAAGGCA TCAAGTATCG GAAGAATGAG GTGTTCTTGG ACGTCATCGA GTCTGTCAAC
CTCTTGGGTA AATACCCAGG AGTGGGATGG CTGGGTCACA CGGTCAGCGC CAACGGCAAT
GTCCTGCGCA GCGAGATCGT GGGCTCCATC AAGATGCGAG TCTTCCTCTC GGGCATGCCC
GAGCTGCGCC TGGGCCTCAA CGACAAGGTC CTCTTTGACA ACACGGGCCG CGGCAAAAGC
AAATCCGTGG AGCTGGAGGA TGTGAAGTTC CACCAGTGTG TGCGGCTATC ACGCTTCGAG
AATGACCGCA CCATCTCCTT CATCCCACCC GACGGCGAGT TCGAGCTCAT GTCCTACCGT
CTCAACACCC ACGTCAAGCC TTTGATATGG ATCGAGTCGG TGATCGAGAA GCACTCCCAC
AGCCGCATCG AGTACATGAT CAAGGCCAAA AGCCAGTTCA AGCGGCGGTC AACAGCCAAC
AACGTGGAGA TCCACATTCC CGTGCCCAAT GATGCCGACT CACCCAAGTT CAAGACGACG
GTGGGGAGCG TTAAGTGGGT CCCCGAGAAC AGCGAGATCG TGTGGTCCAT CAAGTCCTTC
CCGGGCGGCA AGGAGTACCT GATGCGGGCC CACTTCGGCC TGCCTAGTGT GGAGGCCGAA
GACAAGGAGG GCAAGCCCCC GATCAGTGTC AAGTTCGAGA TCCCTTACTT CACTACCTCC
GGCATCCAGG TGCGCTACCT GAAGATCATT GAGAAGAGTG GGTACCAGGC CCTGCCCTGG
GTGCGTTATA TCACGCAGAA TGGAGATTAC CAGCTCCGGA CCCAGTGA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq NP_001123996.1
CDS174..1481
Misc Feature(1)69..71
Misc Feature(2)630..1475
Misc Feature(3)order(669..671,765..767,771..773,777..782,810..812,840..842,909..911,918..920,990..992,1011..1013,1017..1019,1023..1025,1059..1061,1095..1097,1101..1103,1119..1121,1134..1136,1191..1193,1206..1208,1215..1220,1245..1247,1263..1268,1272..1274,1344..1352,1359..1361,1386..1397,1422..1436,1449..1451,1455..1460)
Misc Feature(4)order(687..695,810..812,1131..1133,1350..1352,1356..1358,1428..1439,1443..1445)
Exon (1)1..215
Exon (2)216..372
Exon (3)373..440
Exon (4)441..571
Exon (5)572..719
Exon (6)720..755
Exon (7)756..882
Exon (8)883..1025
Exon (9)1026..1097
Exon (10)1098..1256
Exon (11)1257..1382
Exon (12)1383..1458
Exon (13)1459..2391
Translation

Target ORF information:

RefSeq Version NM_001130524.1
Organism Homo sapiens(Human)
Definition Homo sapiens adaptor related protein complex 1 mu 1 subunit (AP1M1), transcript variant 1, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
NM_001130524.1

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
ATGTCCGCCA GCGCCGTCTA CGTGCTGGAC CTGAAGGGCA AGGTGCTCAT CTGCCGGAAC 
TACCGTGGCG ACGTGGACAT GTCAGAGGTG GAGCACTTCA TGCCCATCCT GATGGAGAAG
GAGGAGGAGG GGATGCTGTC GCCCATCCTG GCCCACGGGG GGGTCCGTTT CATGTGGATC
AAACACAACA ACCTGTATCT GGTTGCCACA TCCAAGAAGA ACGCGTGCGT GTCGCTGGTC
TTTTCTTTCC TCTATAAGGT GGTGCAGGTG TTTTCCGAGT ACTTCAAGGA GCTGGAGGAG
GAGAGCATCC GGGACAACTT TGTTATCATC TACGAGCTGC TGGACGAGCT CATGGACTTC
GGCTACCCCC AGACCACCGA CAGCAAGATC CTGCAGGAGT ACATCACTCA GGAAGGCCAC
AAGCTGGAAA CAGGGGCCCC GCGGCCACCA GCCACCGTCA CCAACGCGGT GTCCTGGCGG
TCCGAAGGCA TCAAGTATCG GAAGAATGAG GTGTTCTTGG ACGTCATCGA GTCTGTCAAC
CTCTTGGGTA AATACCCAGG AGTGGGATGG CTGGGTCACA CGGTCAGCGC CAACGGCAAT
GTCCTGCGCA GCGAGATCGT GGGCTCCATC AAGATGCGAG TCTTCCTCTC GGGCATGCCC
GAGCTGCGCC TGGGCCTCAA CGACAAGGTC CTCTTTGACA ACACGGGCCG CGGCAAAAGC
AAATCCGTGG AGCTGGAGGA TGTGAAGTTC CACCAGTGTG TGCGGCTATC ACGCTTCGAG
AATGACCGCA CCATCTCCTT CATCCCACCC GACGGCGAGT TCGAGCTCAT GTCCTACCGT
CTCAACACCC ACGTCAAGCC TTTGATATGG ATCGAGTCGG TGATCGAGAA GCACTCCCAC
AGCCGCATCG AGTACATGAT CAAGGCCAAA AGCCAGTTCA AGCGGCGGTC AACAGCCAAC
AACGTGGAGA TCCACATTCC CGTGCCCAAT GATGCCGACT CACCCAAGTT CAAGACGACG
GTGGGGAGCG TTAAGTGGGT CCCCGAGAAC AGCGAGATCG TGTGGTCCAT CAAGTCCTTC
CCGGGCGGCA AGGAGTACCT GATGCGGGCC CACTTCGGCC TGCCTAGTGT GGAGGCCGAA
GACAAGGAGG GCAAGCCCCC GATCAGTGTC AAGTTCGAGA TCCCTTACTT CACTACCTCC
GGCATCCAGG TGCGCTACCT GAAGATCATT GAGAAGAGTG GGTACCAGGC CCTGCCCTGG
GTGCGTTATA TCACGCAGAA TGGAGATTAC CAGCTCCGGA CCCAGTGA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OHu30674
Clone ID Related Accession (Same CDS sequence) NM_032493.3
Accession Version NM_032493.3 Latest version! Documents for ORF clone product in dufault vector
Sequence Information ORF Nucleotide Sequence (Length: 1272bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ® Seamless cloning technology
Insert Structure linear
Update Date 2017-05-04
Organism Homo sapiens(Human)
Product AP-1 complex subunit mu-1 isoform 2
Comment REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from DC386056.1, BC017469.2, AK027528.1, BU729646.1 and BQ014582.1. On Jul 26, 2008 this sequence version replaced NM_032493.2. Transcript Variant: This variant (2) lacks a coding exon in the middle region, as compared to variant 1. The reading frame is not affected and the resulting isoform (2) lacks an internal segment, as compared to isoform 1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1803612.237940.1, SRR1803611.106106.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
ATGTCCGCCA GCGCCGTCTA CGTGCTGGAC CTGAAGGGCA AGGTGCTCAT CTGCCGGAAC 
TACCGTGGCG ACGTGGACAT GTCAGAGGTG GAGCACTTCA TGCCCATCCT GATGGAGAAG
GAGGAGGAGG GGATGCTGTC GCCCATCCTG GCCCACGGGG GGGTCCGTTT CATGTGGATC
AAACACAACA ACCTGTATCT GGTTGCCACA TCCAAGAAGA ACGCGTGCGT GTCGCTGGTC
TTTTCTTTCC TCTATAAGGT GGTGCAGGTG TTTTCCGAGT ACTTCAAGGA GCTGGAGGAG
GAGAGCATCC GGGACAACTT TGTTATCATC TACGAGCTGC TGGACGAGCT CATGGACTTC
GGCTACCCCC AGACCACCGA CAGCAAGATC CTGCAGGAGT ACATCACTCA GGAAGGCCAC
AAGCTGGAAA CAGGGGCCCC GCGGCCACCA GCCACCGTCA CCAACGCGGT GTCCTGGCGG
TCCGAAGGCA TCAAGTATCG GAAGAATGAG GTGTTCTTGG ACGTCATCGA GTCTGTCAAC
CTCTTGGTCA GCGCCAACGG CAATGTCCTG CGCAGCGAGA TCGTGGGCTC CATCAAGATG
CGAGTCTTCC TCTCGGGCAT GCCCGAGCTG CGCCTGGGCC TCAACGACAA GGTCCTCTTT
GACAACACGG GCCGCGGCAA AAGCAAATCC GTGGAGCTGG AGGATGTGAA GTTCCACCAG
TGTGTGCGGC TATCACGCTT CGAGAATGAC CGCACCATCT CCTTCATCCC ACCCGACGGC
GAGTTCGAGC TCATGTCCTA CCGTCTCAAC ACCCACGTCA AGCCTTTGAT ATGGATCGAG
TCGGTGATCG AGAAGCACTC CCACAGCCGC ATCGAGTACA TGATCAAGGC CAAAAGCCAG
TTCAAGCGGC GGTCAACAGC CAACAACGTG GAGATCCACA TTCCCGTGCC CAATGATGCC
GACTCACCCA AGTTCAAGAC GACGGTGGGG AGCGTTAAGT GGGTCCCCGA GAACAGCGAG
ATCGTGTGGT CCATCAAGTC CTTCCCGGGC GGCAAGGAGT ACCTGATGCG GGCCCACTTC
GGCCTGCCTA GTGTGGAGGC CGAAGACAAG GAGGGCAAGC CCCCGATCAG TGTCAAGTTC
GAGATCCCTT ACTTCACTAC CTCCGGCATC CAGGTGCGCT ACCTGAAGAT CATTGAGAAG
AGTGGGTACC AGGCCCTGCC CTGGGTGCGT TATATCACGC AGAATGGAGA TTACCAGCTC
CGGACCCAGT GA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq NP_115882.1
CDS174..1445
Misc Feature(1)69..71
Misc Feature(2)177..179
Misc Feature(3)627..629
Misc Feature(4)630..1439
Misc Feature(5)633..635
Misc Feature(6)order(669..671,729..731,735..737,741..746,774..776,804..806,873..875,882..884,954..956,975..977,981..983,987..989,1023..1025,1059..1061,1065..1067,1083..1085,1098..1100,1155..1157,1170..1172,1179..1184,1209..1211,1227..1232,1236..1238,1308..1316,1323..1325,1350..1361,1386..1400,1413..1415,1419..1424)
Misc Feature(7)order(687..695,774..776,1095..1097,1314..1316,1320..1322,1392..1403,1407..1409)
Misc Feature(8)840..842
Exon (1)1..215
Exon (2)216..372
Exon (3)373..440
Exon (4)441..571
Exon (5)572..719
Exon (6)720..846
Exon (7)847..989
Exon (8)990..1061
Exon (9)1062..1220
Exon (10)1221..1346
Exon (11)1347..1422
Exon (12)1423..2355
Translation

Target ORF information:

RefSeq Version NM_032493.3
Organism Homo sapiens(Human)
Definition Homo sapiens adaptor related protein complex 1 mu 1 subunit (AP1M1), transcript variant 2, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
NM_032493.3

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
ATGTCCGCCA GCGCCGTCTA CGTGCTGGAC CTGAAGGGCA AGGTGCTCAT CTGCCGGAAC 
TACCGTGGCG ACGTGGACAT GTCAGAGGTG GAGCACTTCA TGCCCATCCT GATGGAGAAG
GAGGAGGAGG GGATGCTGTC GCCCATCCTG GCCCACGGGG GGGTCCGTTT CATGTGGATC
AAACACAACA ACCTGTATCT GGTTGCCACA TCCAAGAAGA ACGCGTGCGT GTCGCTGGTC
TTTTCTTTCC TCTATAAGGT GGTGCAGGTG TTTTCCGAGT ACTTCAAGGA GCTGGAGGAG
GAGAGCATCC GGGACAACTT TGTTATCATC TACGAGCTGC TGGACGAGCT CATGGACTTC
GGCTACCCCC AGACCACCGA CAGCAAGATC CTGCAGGAGT ACATCACTCA GGAAGGCCAC
AAGCTGGAAA CAGGGGCCCC GCGGCCACCA GCCACCGTCA CCAACGCGGT GTCCTGGCGG
TCCGAAGGCA TCAAGTATCG GAAGAATGAG GTGTTCTTGG ACGTCATCGA GTCTGTCAAC
CTCTTGGTCA GCGCCAACGG CAATGTCCTG CGCAGCGAGA TCGTGGGCTC CATCAAGATG
CGAGTCTTCC TCTCGGGCAT GCCCGAGCTG CGCCTGGGCC TCAACGACAA GGTCCTCTTT
GACAACACGG GCCGCGGCAA AAGCAAATCC GTGGAGCTGG AGGATGTGAA GTTCCACCAG
TGTGTGCGGC TATCACGCTT CGAGAATGAC CGCACCATCT CCTTCATCCC ACCCGACGGC
GAGTTCGAGC TCATGTCCTA CCGTCTCAAC ACCCACGTCA AGCCTTTGAT ATGGATCGAG
TCGGTGATCG AGAAGCACTC CCACAGCCGC ATCGAGTACA TGATCAAGGC CAAAAGCCAG
TTCAAGCGGC GGTCAACAGC CAACAACGTG GAGATCCACA TTCCCGTGCC CAATGATGCC
GACTCACCCA AGTTCAAGAC GACGGTGGGG AGCGTTAAGT GGGTCCCCGA GAACAGCGAG
ATCGTGTGGT CCATCAAGTC CTTCCCGGGC GGCAAGGAGT ACCTGATGCG GGCCCACTTC
GGCCTGCCTA GTGTGGAGGC CGAAGACAAG GAGGGCAAGC CCCCGATCAG TGTCAAGTTC
GAGATCCCTT ACTTCACTAC CTCCGGCATC CAGGTGCGCT ACCTGAAGAT CATTGAGAAG
AGTGGGTACC AGGCCCTGCC CTGGGTGCGT TATATCACGC AGAATGGAGA TTACCAGCTC
CGGACCCAGT GA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OHu62299
Clone ID Related Accession (Same CDS sequence) XM_017027421.1
Accession Version XM_017027421.1 Latest version! Documents for ORF clone product in dufault vector
Sequence Information ORF Nucleotide Sequence (Length: 1194bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ® Seamless cloning technology
Insert Structure linear
Update Date 2016-06-06
Organism Homo sapiens(Human)
Product AP-1 complex subunit mu-1 isoform X2
Comment MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000019.10) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Homo sapiens Annotation Release 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
ATGTCAGAGG TGGAGCACTT CATGCCCATC CTGATGGAGA AGGAGGAGGA GGGGATGCTG 
TCGCCCATCC TGGCCCACGG GGGGGTCCGT TTCATGTGGA TCAAACACAA CAACCTGTAT
CTGGTTGCCA CATCCAAGAA GAACGCGTGC GTGTCGCTGG TCTTTTCTTT CCTCTATAAG
GTGGTGCAGG TGTTTTCCGA GTACTTCAAG GAGCTGGAGG AGGAGAGCAT CCGGGACAAC
TTTGTTATCA TCTACGAGCT GCTGGACGAG CTCATGGACT TCGGCTACCC CCAGACCACC
GACAGCAAGA TCCTGCAGGA GTACATCACT CAGGAAGGCC ACAAGCTGGA AACAGGGGCC
CCGCGGCCAC CAGCCACCGT CACCAACGCG GTGTCCTGGC GGTCCGAAGG CATCAAGTAT
CGGAAGAATG AGGTGTTCTT GGACGTCATC GAGTCTGTCA ACCTCTTGGT CAGCGCCAAC
GGCAATGTCC TGCGCAGCGA GATCGTGGGC TCCATCAAGA TGCGAGTCTT CCTCTCGGGC
ATGCCCGAGC TGCGCCTGGG CCTCAACGAC AAGGTCCTCT TTGACAACAC GGGCCGCGGC
AAAAGCAAAT CCGTGGAGCT GGAGGATGTG AAGTTCCACC AGTGTGTGCG GCTATCACGC
TTCGAGAATG ACCGCACCAT CTCCTTCATC CCACCCGACG GCGAGTTCGA GCTCATGTCC
TACCGTCTCA ACACCCACGT CAAGCCTTTG ATATGGATCG AGTCGGTGAT CGAGAAGCAC
TCCCACAGCC GCATCGAGTA CATGATCAAG GCCAAAAGCC AGTTCAAGCG GCGGTCAACA
GCCAACAACG TGGAGATCCA CATTCCCGTG CCCAATGATG CCGACTCACC CAAGTTCAAG
ACGACGGTGG GGAGCGTTAA GTGGGTCCCC GAGAACAGCG AGATCGTGTG GTCCATCAAG
TCCTTCCCGG GCGGCAAGGA GTACCTGATG CGGGCCCACT TCGGCCTGCC TAGTGTGGAG
GCCGAAGACA AGGAGGGCAA GCCCCCGATC AGTGTCAAGT TCGAGATCCC TTACTTCACT
ACCTCCGGCA TCCAGGTGCG CTACCTGAAG ATCATTGAGA AGAGTGGGTA CCAGGCCCTG
CCCTGGGTGC GTTATATCAC GCAGAATGGA GATTACCAGC TCCGGACCCA GTGA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq XP_016882910.1
CDS192..1385
Misc Feature(1)570..1379
Misc Feature(2)order(609..611,669..671,675..677,681..686,714..716,744..746,813..815,822..824,894..896,915..917,921..923,927..929,963..965,999..1001,1005..1007,1023..1025,1038..1040,1095..1097,1110..1112,1119..1124,1149..1151,1167..1172,1176..1178,1248..1256,1263..1265,1290..1301,1326..1340,1353..1355,1359..1364)
Misc Feature(3)order(627..635,714..716,1035..1037,1254..1256,1260..1262,1332..1343,1347..1349)
Translation

Target ORF information:

RefSeq Version XM_017027421.1
Organism Homo sapiens(Human)
Definition Homo sapiens adaptor related protein complex 1 mu 1 subunit (AP1M1), transcript variant X2, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
XM_017027421.1

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
ATGTCAGAGG TGGAGCACTT CATGCCCATC CTGATGGAGA AGGAGGAGGA GGGGATGCTG 
TCGCCCATCC TGGCCCACGG GGGGGTCCGT TTCATGTGGA TCAAACACAA CAACCTGTAT
CTGGTTGCCA CATCCAAGAA GAACGCGTGC GTGTCGCTGG TCTTTTCTTT CCTCTATAAG
GTGGTGCAGG TGTTTTCCGA GTACTTCAAG GAGCTGGAGG AGGAGAGCAT CCGGGACAAC
TTTGTTATCA TCTACGAGCT GCTGGACGAG CTCATGGACT TCGGCTACCC CCAGACCACC
GACAGCAAGA TCCTGCAGGA GTACATCACT CAGGAAGGCC ACAAGCTGGA AACAGGGGCC
CCGCGGCCAC CAGCCACCGT CACCAACGCG GTGTCCTGGC GGTCCGAAGG CATCAAGTAT
CGGAAGAATG AGGTGTTCTT GGACGTCATC GAGTCTGTCA ACCTCTTGGT CAGCGCCAAC
GGCAATGTCC TGCGCAGCGA GATCGTGGGC TCCATCAAGA TGCGAGTCTT CCTCTCGGGC
ATGCCCGAGC TGCGCCTGGG CCTCAACGAC AAGGTCCTCT TTGACAACAC GGGCCGCGGC
AAAAGCAAAT CCGTGGAGCT GGAGGATGTG AAGTTCCACC AGTGTGTGCG GCTATCACGC
TTCGAGAATG ACCGCACCAT CTCCTTCATC CCACCCGACG GCGAGTTCGA GCTCATGTCC
TACCGTCTCA ACACCCACGT CAAGCCTTTG ATATGGATCG AGTCGGTGAT CGAGAAGCAC
TCCCACAGCC GCATCGAGTA CATGATCAAG GCCAAAAGCC AGTTCAAGCG GCGGTCAACA
GCCAACAACG TGGAGATCCA CATTCCCGTG CCCAATGATG CCGACTCACC CAAGTTCAAG
ACGACGGTGG GGAGCGTTAA GTGGGTCCCC GAGAACAGCG AGATCGTGTG GTCCATCAAG
TCCTTCCCGG GCGGCAAGGA GTACCTGATG CGGGCCCACT TCGGCCTGCC TAGTGTGGAG
GCCGAAGACA AGGAGGGCAA GCCCCCGATC AGTGTCAAGT TCGAGATCCC TTACTTCACT
ACCTCCGGCA TCCAGGTGCG CTACCTGAAG ATCATTGAGA AGAGTGGGTA CCAGGCCCTG
CCCTGGGTGC GTTATATCAC GCAGAATGGA GATTACCAGC TCCGGACCCA GTGA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OHu88790
Clone ID Related Accession (Same CDS sequence) XM_017027420.1
Accession Version XM_017027420.1 Latest version! Documents for ORF clone product in dufault vector
Sequence Information ORF Nucleotide Sequence (Length: 1230bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ® Seamless cloning technology
Insert Structure linear
Update Date 2016-06-06
Organism Homo sapiens(Human)
Product AP-1 complex subunit mu-1 isoform X1
Comment MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000019.10) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Homo sapiens Annotation Release 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
ATGTCAGAGG TGGAGCACTT CATGCCCATC CTGATGGAGA AGGAGGAGGA GGGGATGCTG 
TCGCCCATCC TGGCCCACGG GGGGGTCCGT TTCATGTGGA TCAAACACAA CAACCTGTAT
CTGGTTGCCA CATCCAAGAA GAACGCGTGC GTGTCGCTGG TCTTTTCTTT CCTCTATAAG
GTGGTGCAGG TGTTTTCCGA GTACTTCAAG GAGCTGGAGG AGGAGAGCAT CCGGGACAAC
TTTGTTATCA TCTACGAGCT GCTGGACGAG CTCATGGACT TCGGCTACCC CCAGACCACC
GACAGCAAGA TCCTGCAGGA GTACATCACT CAGGAAGGCC ACAAGCTGGA AACAGGGGCC
CCGCGGCCAC CAGCCACCGT CACCAACGCG GTGTCCTGGC GGTCCGAAGG CATCAAGTAT
CGGAAGAATG AGGTGTTCTT GGACGTCATC GAGTCTGTCA ACCTCTTGGG TAAATACCCA
GGAGTGGGAT GGCTGGGTCA CACGGTCAGC GCCAACGGCA ATGTCCTGCG CAGCGAGATC
GTGGGCTCCA TCAAGATGCG AGTCTTCCTC TCGGGCATGC CCGAGCTGCG CCTGGGCCTC
AACGACAAGG TCCTCTTTGA CAACACGGGC CGCGGCAAAA GCAAATCCGT GGAGCTGGAG
GATGTGAAGT TCCACCAGTG TGTGCGGCTA TCACGCTTCG AGAATGACCG CACCATCTCC
TTCATCCCAC CCGACGGCGA GTTCGAGCTC ATGTCCTACC GTCTCAACAC CCACGTCAAG
CCTTTGATAT GGATCGAGTC GGTGATCGAG AAGCACTCCC ACAGCCGCAT CGAGTACATG
ATCAAGGCCA AAAGCCAGTT CAAGCGGCGG TCAACAGCCA ACAACGTGGA GATCCACATT
CCCGTGCCCA ATGATGCCGA CTCACCCAAG TTCAAGACGA CGGTGGGGAG CGTTAAGTGG
GTCCCCGAGA ACAGCGAGAT CGTGTGGTCC ATCAAGTCCT TCCCGGGCGG CAAGGAGTAC
CTGATGCGGG CCCACTTCGG CCTGCCTAGT GTGGAGGCCG AAGACAAGGA GGGCAAGCCC
CCGATCAGTG TCAAGTTCGA GATCCCTTAC TTCACTACCT CCGGCATCCA GGTGCGCTAC
CTGAAGATCA TTGAGAAGAG TGGGTACCAG GCCCTGCCCT GGGTGCGTTA TATCACGCAG
AATGGAGATT ACCAGCTCCG GACCCAGTGA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq XP_016882909.1
CDS192..1421
Translation

Target ORF information:

RefSeq Version XM_017027420.1
Organism Homo sapiens(Human)
Definition Homo sapiens adaptor related protein complex 1 mu 1 subunit (AP1M1), transcript variant X1, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
XM_017027420.1

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
ATGTCAGAGG TGGAGCACTT CATGCCCATC CTGATGGAGA AGGAGGAGGA GGGGATGCTG 
TCGCCCATCC TGGCCCACGG GGGGGTCCGT TTCATGTGGA TCAAACACAA CAACCTGTAT
CTGGTTGCCA CATCCAAGAA GAACGCGTGC GTGTCGCTGG TCTTTTCTTT CCTCTATAAG
GTGGTGCAGG TGTTTTCCGA GTACTTCAAG GAGCTGGAGG AGGAGAGCAT CCGGGACAAC
TTTGTTATCA TCTACGAGCT GCTGGACGAG CTCATGGACT TCGGCTACCC CCAGACCACC
GACAGCAAGA TCCTGCAGGA GTACATCACT CAGGAAGGCC ACAAGCTGGA AACAGGGGCC
CCGCGGCCAC CAGCCACCGT CACCAACGCG GTGTCCTGGC GGTCCGAAGG CATCAAGTAT
CGGAAGAATG AGGTGTTCTT GGACGTCATC GAGTCTGTCA ACCTCTTGGG TAAATACCCA
GGAGTGGGAT GGCTGGGTCA CACGGTCAGC GCCAACGGCA ATGTCCTGCG CAGCGAGATC
GTGGGCTCCA TCAAGATGCG AGTCTTCCTC TCGGGCATGC CCGAGCTGCG CCTGGGCCTC
AACGACAAGG TCCTCTTTGA CAACACGGGC CGCGGCAAAA GCAAATCCGT GGAGCTGGAG
GATGTGAAGT TCCACCAGTG TGTGCGGCTA TCACGCTTCG AGAATGACCG CACCATCTCC
TTCATCCCAC CCGACGGCGA GTTCGAGCTC ATGTCCTACC GTCTCAACAC CCACGTCAAG
CCTTTGATAT GGATCGAGTC GGTGATCGAG AAGCACTCCC ACAGCCGCAT CGAGTACATG
ATCAAGGCCA AAAGCCAGTT CAAGCGGCGG TCAACAGCCA ACAACGTGGA GATCCACATT
CCCGTGCCCA ATGATGCCGA CTCACCCAAG TTCAAGACGA CGGTGGGGAG CGTTAAGTGG
GTCCCCGAGA ACAGCGAGAT CGTGTGGTCC ATCAAGTCCT TCCCGGGCGG CAAGGAGTAC
CTGATGCGGG CCCACTTCGG CCTGCCTAGT GTGGAGGCCG AAGACAAGGA GGGCAAGCCC
CCGATCAGTG TCAAGTTCGA GATCCCTTAC TTCACTACCT CCGGCATCCA GGTGCGCTAC
CTGAAGATCA TTGAGAAGAG TGGGTACCAG GCCCTGCCCT GGGTGCGTTA TATCACGCAG
AATGGAGATT ACCAGCTCCG GACCCAGTGA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

book

Basolateral sorting of the Mg²⁺ transporter CNNM4 requires interaction with AP-1A and AP-1B.
Biochemical and biophysical research communications455(3-4)184-9(2014 Dec)
Hirata Y,Funato Y,Miki H


book

Adaptor protein 1 promotes cross-presentation through the same tyrosine signal in major histocompatibility complex class I as that targeted by HIV-1.
Journal of virology87(14)8085-98(2013 Jul)
Kulpa DA,Del Cid N,Peterson KA,Collins KL


book

The AP-1 complex regulates intracellular localization of insulin receptor substrate 1, which is required for insulin-like growth factor I-dependent cell proliferation.
Molecular and cellular biology33(10)1991-2003(2013 May)
Yoneyama Y,Matsuo M,Take K,Kabuta T,Chida K,Hakuno F,Takahashi S


book

A noncanonical mu-1A-binding motif in the N terminus of HIV-1 Nef determines its ability to downregulate major histocompatibility complex class I in T lymphocytes.
Journal of virology86(7)3944-51(2012 Apr)
Iijima S,Lee YJ,Ode H,Arold ST,Kimura N,Yokoyama M,Sato H,Tanaka Y,Strebel K,Akari H


book

Human kidney anion exchanger 1 interacts with adaptor-related protein complex 1 μ1A (AP-1 mu1A).
Biochemical and biophysical research communications401(1)85-91(2010 Oct)
Sawasdee N,Junking M,Ngaojanlar P,Sukomon N,Ungsupravate D,Limjindaporn T,Akkarapatumwong V,Noisakran S,Yenchitsomanus PT


 
*
*
*
*