Gene Symbol | DCAF15 |
Entrez Gene ID | 90379 |
Full Name | DDB1 and CUL4 associated factor 15 |
Synonyms | C19orf72 |
General protein information |
|
Gene Type | protein-coding |
Organism | Homo sapiens(human) |
Genome |
ORF » Species Summary » Homo sapiens » DCAF15 cDNA ORF clone
Gene Symbol | DCAF15 |
Entrez Gene ID | 90379 |
Full Name | DDB1 and CUL4 associated factor 15 |
Synonyms | C19orf72 |
General protein information |
|
Gene Type | protein-coding |
Organism | Homo sapiens(human) |
Genome |
mRNA | Protein | Name |
---|---|---|
NM_138353.2 | NP_612362.2 | DDB1- and CUL4-associated factor 15 |
NM_138353.3 | NP_612362.2 | DDB1- and CUL4-associated factor 15 |
Homo sapiens (human) | DCAF15 | NP_612362.2 |
Pan troglodytes (chimpanzee) | DCAF15 | XP_524449.4 |
Rattus norvegicus (Norway rat) | Dcaf15 | NP_001100632.1 |
DCAF15 | XP_001111304.1 | |
Bos taurus (cattle) | DCAF15 | NP_001029857.1 |
Danio rerio (zebrafish) | dcaf15 | XP_682800.2 |
Mus musculus (house mouse) | Dcaf15 | NP_766090.2 |
Canis lupus familiaris (dog) | DCAF15 | XP_003639829.1 |
Xenopus tropicalis (tropical clawed frog) | dcaf15 | XP_004919204.1 |
Selective degradation of splicing factor CAPER? by anticancer sulfonamides.
Uehara T, Minoshima Y, Sagane K, Sugi NH, Mitsuhashi KO, Yamamoto N, Kamiyama H, Takahashi K, Kotake Y, Uesugi M, Yokoi A, Inoue A, Yoshida T, Mabuchi M, Tanaka A, Owa T
Nature chemical biology13(6)675-680(2017 Jun)
Anticancer sulfonamides target splicing by inducing RBM39 degradation via recruitment to DCAF15.
Han T, Goralski M, Gaskill N, Capota E, Kim J, Ting TC, Xie Y, Williams NS, Nijhawan D
Science (New York, N.Y.)356(6336)(2017 04)
A family of diverse Cul4-Ddb1-interacting proteins includes Cdt2, which is required for S phase destruction of the replication factor Cdt1.
Jin J, Arias EE, Chen J, Harper JW, Walter JC
Molecular cell23(5)709-21(2006 Sep)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
DCAF15 expression may be a useful biomarker to guide clinical trials of splicing inhibitor sulfonamides(SPLAMs).
Title: Anticancer sulfonamides target splicing by inducing RBM39 degradation via recruitment to DCAF15.
The following DCAF15 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the DCAF15 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
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CloneID | OHu06074 | |
Clone ID Related Accession (Same CDS sequence) | NM_138353.2 , NM_138353.3 | |
Accession Version | NM_138353.2 | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1803bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2015-03-14 | |
Organism | Homo sapiens(Human) | |
Product | DDB1- and CUL4-associated factor 15 | |
Comment |
1 | ATGGCGCCCA GCTCGAAATC GGAGCGGAAC AGCGGGGCTG GGAGCGGCGG CGGCGGCCCC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_612362.2 |
Translation |
Target ORF information:
Target ORF information:
|
NM_138353.2 |
1 | ATGGCGCCCA GCTCGAAATC GGAGCGGAAC AGCGGGGCTG GGAGCGGCGG CGGCGGCCCC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OHu06074 | |
Clone ID Related Accession (Same CDS sequence) | NM_138353.2 , NM_138353.3 | |
Accession Version | NM_138353.3 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1803bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-12-28 | |
Organism | Homo sapiens(human) | |
Product | DDB1- and CUL4-associated factor 15 | |
Comment | Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from HY003563.1, BC080575.1 and BC018894.2. On Jul 22, 2016 this sequence version replaced NM_138353.2. ##Evidence-Data-START## Transcript exon combination :: SRR1163658.416831.1, BC080575.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## RefSeq Select criteria :: based on single protein-coding transcript ##RefSeq-Attributes-END## COMPLETENESS: complete on the 3' end. |
1 | ATGGCGCCCA GCTCGAAATC GGAGCGGAAC AGCGGGGCTG GGAGCGGCGG CGGCGGCCCC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_612362.2 |
CDS | 40..1842 |
Translation |
Target ORF information:
Target ORF information:
|
NM_138353.3 |
1 | ATGGCGCCCA GCTCGAAATC GGAGCGGAAC AGCGGGGCTG GGAGCGGCGG CGGCGGCCCC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
Selective degradation of splicing factor CAPER? by anticancer sulfonamides. |
Anticancer sulfonamides target splicing by inducing RBM39 degradation via recruitment to DCAF15. |
A family of diverse Cul4-Ddb1-interacting proteins includes Cdt2, which is required for S phase destruction of the replication factor Cdt1. |