×

LRSAM1 cDNA ORF clone, Homo sapiens(Human)

Gene Symbol LRSAM1
Entrez Gene ID 90678
Full Name leucine rich repeat and sterile alpha motif containing 1
Synonyms CMT2P,RIFLE,TAL
General protein information
Preferred Names

leucine rich repeat and sterile alpha motif containing 1

Names

E3 ubiquitin-protein ligase LRSAM1
RING-type E3 ubiquitin transferase LRSAM1
Tsg101-associated ligase

Gene Type protein-coding
Organism Homo sapiens(Human)
Genome

9

9q33.3-q34.11

Disorder MIM:

610933


mRNA and Protein(s)

mRNA Protein Name
XM_017015284.1 XP_016870773.1 E3 ubiquitin-protein ligase LRSAM1 isoform X3
NM_001005373.3 NP_001005373.1 E3 ubiquitin-protein ligase LRSAM1 isoform 1
XM_006717316.3 XP_006717379.1 E3 ubiquitin-protein ligase LRSAM1 isoform X2
NM_001190723.2 NP_001177652.1 E3 ubiquitin-protein ligase LRSAM1 isoform 2
NM_138361.5 NP_612370.3 E3 ubiquitin-protein ligase LRSAM1 isoform 1
XM_017015283.1 XP_016870772.1 E3 ubiquitin-protein ligase LRSAM1 isoform X1
NM_001005374.3 NP_001005374.1 E3 ubiquitin-protein ligase LRSAM1 isoform 1



Mus musculus (house mouse) Lrsam1 NP_955006.1
Rattus norvegicus (Norway rat) Lrsam1 NP_001101303.1
Gallus gallus (chicken) LRSAM1 XP_004945836.1
Homo sapiens (human) LRSAM1 NP_612370.3
Canis lupus familiaris (dog) LRSAM1 XP_548450.2
Macaca mulatta (rhesus monkey) LRSAM1 XP_002800233.1
Pan troglodytes (chimpanzee) LRSAM1 XP_001149113.1
Bos taurus (cattle) LRSAM1 NP_001068764.1
Anopheles gambiae (African malaria mosquito) AgaP_AGAP005053 XP_001230957.2
Xenopus tropicalis (tropical clawed frog) lrsam1 XP_002940776.2
Danio rerio (zebrafish) lrsam1 NP_001093474.1


Related articles in PubMed

The MEKK1 PHD ubiquitinates TAB1 to activate MAPKs in response to cytokines.
Charlaftis N, Suddason T, Wu X, Anwar S, Karin M, Gallagher E
The EMBO journal33(21)2581-96(2014 Nov)

A novel mutation in LRSAM1 causes axonal Charcot-Marie-Tooth disease with dominant inheritance.
Engeholm M, Sekler J, Schöndorf DC, Arora V, Schittenhelm J, Biskup S, Schell C, Gasser T
BMC neurology14118(2014 Jun)

PHF23 (plant homeodomain finger protein 23) negatively regulates cell autophagy by promoting ubiquitination and degradation of E3 ligase LRSAM1.
Wang Z, Hu J, Li G, Qu L, He Q, Lou Y, Song Q, Ma D, Chen Y
Autophagy10(12)2158-70(2014)

The LRR and RING domain protein LRSAM1 is an E3 ligase crucial for ubiquitin-dependent autophagy of intracellular Salmonella Typhimurium.
Huett A, Heath RJ, Begun J, Sassi SO, Baxt LA, Vyas JM, Goldberg MB, Xavier RJ
Cell host & microbe12(6)778-90(2012 Dec)

Human leucine-rich repeat proteins: a genome-wide bioinformatic categorization and functional analysis in innate immunity.
Ng AC, Eisenberg JM, Heath RJ, Huett A, Robinson CM, Nau GJ, Xavier RJ
Proceedings of the National Academy of Sciences of the United States of America108 Suppl 14631-8(2011 Mar)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

LRSAM1 exhibited self-association in vitro and in vivo. The study found the self-association of LRSAM1 promotes intermolecular ubiquitination and proved a potential N-terminal ubiquitination.
Title: The self-association and activity regulation of LRSAM1 E3 ligase.

findings demonstrate that the isolated genetic entity Charcot-Marie-Tooth type 2G is caused by a missense mutation in LRSAM1.
Title: Charcot-Marie-Tooth disease type 2G redefined by a novel mutation in LRSAM1.

findings suggest that the mutant LRSAM1 may aberrantly affect the formation of transcription machinery.
Title: A novel missense mutation of CMT2P alters transcription machinery.

disruption of the C-terminal RING domain confers dominant negative properties to LRSAM1
Title: A novel mutation in LRSAM1 causes axonal Charcot-Marie-Tooth disease with dominant inheritance.

Plant homeodomain finger protein 23 negatively regulates cell autophagy by promoting ubiquitination and degradation of E3 ligase LRSAM1
Title: PHF23 (plant homeodomain finger protein 23) negatively regulates cell autophagy by promoting ubiquitination and degradation of E3 ligase LRSAM1.

The following LRSAM1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the LRSAM1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

Online Only Promotion

Up to 50% OFF! Starting
from $49/clone

Free DYK Tag Antibody

***CloneID RefSeq Accession Definition **Vector *Turnaround time Price (USD) Select
OHu98997 XM_017015284.1
Latest version!
Homo sapiens leucine rich repeat and sterile alpha motif containing 1 (LRSAM1), transcript variant X3, mRNA. pcDNA3.1+/C-(K)DYK or customized vector 9-11 $223.30
$319.00
OHu26634 NM_138361.5
Latest version!
Homo sapiens leucine rich repeat and sterile alpha motif containing 1 (LRSAM1), transcript variant 1, mRNA. pcDNA3.1+/C-(K)DYK or customized vector 12-14 $265.30
$379.00
OHu26634 NM_001005373.3
Latest version!
Homo sapiens leucine rich repeat and sterile alpha motif containing 1 (LRSAM1), transcript variant 2, mRNA. pcDNA3.1+/C-(K)DYK or customized vector 12-14 $265.30
$379.00
OHu26634 NM_001005374.3
Latest version!
Homo sapiens leucine rich repeat and sterile alpha motif containing 1 (LRSAM1), transcript variant 3, mRNA. pcDNA3.1+/C-(K)DYK or customized vector 12-14 $265.30
$379.00
OHu26960 NM_001190723.2
Latest version!
Homo sapiens leucine rich repeat and sterile alpha motif containing 1 (LRSAM1), transcript variant 4, mRNA. pcDNA3.1+/C-(K)DYK or customized vector 12-14 $489.30
$699.00
OHu26634 XM_017015283.1
Latest version!
Homo sapiens leucine rich repeat and sterile alpha motif containing 1 (LRSAM1), transcript variant X1, mRNA. pcDNA3.1+/C-(K)DYK or customized vector 12-14 $265.30
$379.00
OHu43578 XM_006717316.3
Latest version!
Homo sapiens leucine rich repeat and sterile alpha motif containing 1 (LRSAM1), transcript variant X2, mRNA. pcDNA3.1+/C-(K)DYK or customized vector 12-14 $391.30
$559.00

ORF Online Only Promotion

Next-day Shipping ORF Clones ( in default vector with tag)
1 Clone 30% OFF
2-4 Clone 40% OFF
5 or more Clone 50% OFF
All Other ORF Clones
30% OFF

*Business Day

** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.


CloneID OHu98997
Clone ID Related Accession (Same CDS sequence) XM_017015284.1
Accession Version XM_017015284.1 Latest version! Documents for ORF clone product in dufault vector
Sequence Information ORF Nucleotide Sequence (Length: 1383bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ® Seamless cloning technology
Insert Structure linear
Update Date 2016-06-06
Organism Homo sapiens(Human)
Product E3 ubiquitin-protein ligase LRSAM1 isoform X3
Comment MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000009.12) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Homo sapiens Annotation Release 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
ATGCTGGAGA AACTCGAGTT TGAACGGCGC CTGGAACTGG GGCAGCGGGA GCACACCCAG 
CTCCTTCAGC AGAGCAGCAG CCAGAAGGAT GAGATCCTTC AGACGGTCAA GGAGGAGCAG
TCCCGGCTGG AGCAGGGCCT GAGTGAGCAC CAGCGCCACC TCAACGCAGA GCGGCAGCGG
CTGCAGGAGC AGCTGAAGCA GACGGAACAG AACATTTCCA GCCGGATCCA GAAGCTGCTG
CAGGACAATC AGAGACAAAA GAAAAGCTCC GAGATTTTGA AATCGCTGGA AAATGAAAGA
ATAAGAATGG AACAGTTGAT GTCCATAACC CAGGAGGAGA CTGAGAGCCT GCGGCGACGT
GACGTTGCCT CCGCCATGCA GCAGATGCTG ACTGAGAGCT GTAAGAACCG GCTCATCCAG
ATGGCCTACG AATCTCAGAG GCAGAACTTG GTCCAGCAGG CCTGTTCCAG CATGGCCGAA
ATGGATGAAC GATTCCAGCA GATTCTGTCG TGGCAGCAAA TGGATCAGAA CAAAGCCATC
AGCCAGATCC TGCAGGAGAG CGCGATGCAG AAGGCTGCGT TCGAGGCACT CCAGGTGAAG
AAAGACCTGA TGCATCGGCA GATCAGGAGC CAGATTAAGT TAATAGAAAC TGAGTTATTG
CAGCTGACAC AGCTGGAGTT AAAGAGGAAG TCCCTGGACA CAGAGTCACT CCAGGAGATG
ATCTCGGAGC AGCGCTGGGC CCTCAGCTCC CTGCTCCAGC AGCTGCTCAA AGAGAAGCAG
CAGCGAGAGG AAGAGCTCCG GGAAATCCTG ACGGAGTTAG AAGCCAAAAG TGAAACCAGG
CAGGAAAATT ACTGGCTGAT TCAGTATCAA CGGCTTTTGA ACCAGAAGCC CTTGTCCTTG
AAGCTGCAAG AAGAGGGGAT GGAGCGCCAG CTGGTGGCCC TCCTGGAGGA GCTGTCGGCT
GAGCACTACC TGCCCATCTT TGCGCACCAC CGCCTCTCAC TGGACCTGCT GAGCCAAATG
AGCCCAGGGG ACCTGGCCAA GGTGGGCGTC TCAGAAGCTG GCCTGCAGCA CGAGATCCTC
CGGAGAGTCC AGGAACTGCT GGATGCAGCC AGGATCCAGC CAGAGCTGAA ACCACCAATG
GGTGAGGTCG TCACCCCTAC GGCCCCCCAG GAGCCTCCTG AGTCTGTGAG GCCATCCGCT
CCCCCTGCAG AGCTGGAGGT GCAGGCCTCA GAGTGTGTCG TGTGCCTGGA ACGGGAGGCC
CAGATGATCT TCCTCAACTG TGGCCACGTC TGCTGCTGCC AGCAGTGCTG CCAGCCACTG
CGCACCTGCC CGCTGTGCCG CCAGGACATC GCCCAGCGCC TCCGCATCTA CCACAGCAGC
TGA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq XP_016870773.1
CDS1157..2539
Translation

Target ORF information:

RefSeq Version XM_017015284.1
Organism Homo sapiens(Human)
Definition Homo sapiens leucine rich repeat and sterile alpha motif containing 1 (LRSAM1), transcript variant X3, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
XM_017015284.1

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
ATGCTGGAGA AACTCGAGTT TGAACGGCGC CTGGAACTGG GGCAGCGGGA GCACACCCAG 
CTCCTTCAGC AGAGCAGCAG CCAGAAGGAT GAGATCCTTC AGACGGTCAA GGAGGAGCAG
TCCCGGCTGG AGCAGGGCCT GAGTGAGCAC CAGCGCCACC TCAACGCAGA GCGGCAGCGG
CTGCAGGAGC AGCTGAAGCA GACGGAACAG AACATTTCCA GCCGGATCCA GAAGCTGCTG
CAGGACAATC AGAGACAAAA GAAAAGCTCC GAGATTTTGA AATCGCTGGA AAATGAAAGA
ATAAGAATGG AACAGTTGAT GTCCATAACC CAGGAGGAGA CTGAGAGCCT GCGGCGACGT
GACGTTGCCT CCGCCATGCA GCAGATGCTG ACTGAGAGCT GTAAGAACCG GCTCATCCAG
ATGGCCTACG AATCTCAGAG GCAGAACTTG GTCCAGCAGG CCTGTTCCAG CATGGCCGAA
ATGGATGAAC GATTCCAGCA GATTCTGTCG TGGCAGCAAA TGGATCAGAA CAAAGCCATC
AGCCAGATCC TGCAGGAGAG CGCGATGCAG AAGGCTGCGT TCGAGGCACT CCAGGTGAAG
AAAGACCTGA TGCATCGGCA GATCAGGAGC CAGATTAAGT TAATAGAAAC TGAGTTATTG
CAGCTGACAC AGCTGGAGTT AAAGAGGAAG TCCCTGGACA CAGAGTCACT CCAGGAGATG
ATCTCGGAGC AGCGCTGGGC CCTCAGCTCC CTGCTCCAGC AGCTGCTCAA AGAGAAGCAG
CAGCGAGAGG AAGAGCTCCG GGAAATCCTG ACGGAGTTAG AAGCCAAAAG TGAAACCAGG
CAGGAAAATT ACTGGCTGAT TCAGTATCAA CGGCTTTTGA ACCAGAAGCC CTTGTCCTTG
AAGCTGCAAG AAGAGGGGAT GGAGCGCCAG CTGGTGGCCC TCCTGGAGGA GCTGTCGGCT
GAGCACTACC TGCCCATCTT TGCGCACCAC CGCCTCTCAC TGGACCTGCT GAGCCAAATG
AGCCCAGGGG ACCTGGCCAA GGTGGGCGTC TCAGAAGCTG GCCTGCAGCA CGAGATCCTC
CGGAGAGTCC AGGAACTGCT GGATGCAGCC AGGATCCAGC CAGAGCTGAA ACCACCAATG
GGTGAGGTCG TCACCCCTAC GGCCCCCCAG GAGCCTCCTG AGTCTGTGAG GCCATCCGCT
CCCCCTGCAG AGCTGGAGGT GCAGGCCTCA GAGTGTGTCG TGTGCCTGGA ACGGGAGGCC
CAGATGATCT TCCTCAACTG TGGCCACGTC TGCTGCTGCC AGCAGTGCTG CCAGCCACTG
CGCACCTGCC CGCTGTGCCG CCAGGACATC GCCCAGCGCC TCCGCATCTA CCACAGCAGC
TGA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OHu26634
Clone ID Related Accession (Same CDS sequence) NM_001005373.3 , NM_138361.5 , XM_017015283.1 , NM_001005374.3
Accession Version NM_001005373.3 Latest version! Documents for ORF clone product in dufault vector
Sequence Information ORF Nucleotide Sequence (Length: 2172bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ® Seamless cloning technology
Insert Structure linear
Update Date 2017-03-19
Organism Homo sapiens(Human)
Product E3 ubiquitin-protein ligase LRSAM1 isoform 1
Comment REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from DA165729.1, AY358830.1, BC009239.2 and DB309230.1. On Jan 14, 2012 this sequence version replaced NM_001005373.2. Transcript Variant: This variant (2) differs in the 5' UTR compared to variant 1. Variants 1, 2 and 3 encode the same isoform (1). Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AK226106.1, AY358830.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
1501
1561
1621
1681
1741
1801
1861
1921
1981
2041
2101
2161
ATGCCGCTCT TCTTCCGGAA GCGGAAACCC AGTGAGGAGG CTCGGAAACG CCTGGAGTAC 
CAGATGTGTT TGGCAAAAGA AGCTGGGGCA GATGACATTC TCGACATCTC TAAATGTGAG
CTCTCAGAGA TTCCATTTGG AGCTTTTGCA ACATGCAAAG TTCTGCAGAA GAAGGTGCTG
ATCGTCCACA CGAATCACCT CACTTCCCTG CTTCCCAAAT CCTGCAGCCT CCTGAGTCTG
GCAACCATCA AGGTTCTAGA TCTCCACGAT AATCAGCTGA CAGCCCTTCC TGACGATCTG
GGGCAGCTGA CTGCCCTCCA GGTCTTAAAC GTGGAAAGGA ATCAACTGAT GCAGCTCCCA
CGTTCCATTG GGAACCTGAC CCAGCTCCAG ACTCTCAATG TTAAAGACAA CAAGCTGAAG
GAGCTTCCAG ACACCGTGGG GGAGCTTCGA AGCCTGCGTA CCCTCAACAT CAGTGGAAAC
GAGATCCAGA GATTGCCGCA GATGCTGGCT CACGTTCGAA CCCTGGAGAT GCTGAGCCTT
GACGCCTCGG CCATGGTCTA CCCGCCGCGG GAGGTGTGTG GTGCCGGCAC TGCGGCCATC
TTGCAGTTCC TCTGCAAAGA GTCAGGGCTG GAATACTACC CCCCTTCTCA GTACTTGCTG
CCAATTCTGG AGCAAGATGG AATCGAGAAC TCTCGGGACA GCCCTGATGG GCCCACGGAC
AGATTCTCAA GGGAGGAGTT AGAGTGGCAG AACAGGTTCT CAGACTATGA GAAGAGGAAG
GAACAGAAGA TGCTGGAGAA ACTCGAGTTT GAACGGCGCC TGGAACTGGG GCAGCGGGAG
CACACCCAGC TCCTTCAGCA GAGCAGCAGC CAGAAGGATG AGATCCTTCA GACGGTCAAG
GAGGAGCAGT CCCGGCTGGA GCAGGGCCTG AGTGAGCACC AGCGCCACCT CAACGCAGAG
CGGCAGCGGC TGCAGGAGCA GCTGAAGCAG ACGGAACAGA ACATTTCCAG CCGGATCCAG
AAGCTGCTGC AGGACAATCA GAGACAAAAG AAAAGCTCCG AGATTTTGAA ATCGCTGGAA
AATGAAAGAA TAAGAATGGA ACAGTTGATG TCCATAACCC AGGAGGAGAC TGAGAGCCTG
CGGCGACGTG ACGTTGCCTC CGCCATGCAG CAGATGCTGA CTGAGAGCTG TAAGAACCGG
CTCATCCAGA TGGCCTACGA ATCTCAGAGG CAGAACTTGG TCCAGCAGGC CTGTTCCAGC
ATGGCCGAAA TGGATGAACG ATTCCAGCAG ATTCTGTCGT GGCAGCAAAT GGATCAGAAC
AAAGCCATCA GCCAGATCCT GCAGGAGAGC GCGATGCAGA AGGCTGCGTT CGAGGCACTC
CAGGTGAAGA AAGACCTGAT GCATCGGCAG ATCAGGAGCC AGATTAAGTT AATAGAAACT
GAGTTATTGC AGCTGACACA GCTGGAGTTA AAGAGGAAGT CCCTGGACAC AGAGTCACTC
CAGGAGATGA TCTCGGAGCA GCGCTGGGCC CTCAGCTCCC TGCTCCAGCA GCTGCTCAAA
GAGAAGCAGC AGCGAGAGGA AGAGCTCCGG GAAATCCTGA CGGAGTTAGA AGCCAAAAGT
GAAACCAGGC AGGAAAATTA CTGGCTGATT CAGTATCAAC GGCTTTTGAA CCAGAAGCCC
TTGTCCTTGA AGCTGCAAGA AGAGGGGATG GAGCGCCAGC TGGTGGCCCT CCTGGAGGAG
CTGTCGGCTG AGCACTACCT GCCCATCTTT GCGCACCACC GCCTCTCACT GGACCTGCTG
AGCCAAATGA GCCCAGGGGA CCTGGCCAAG GTGGGCGTCT CAGAAGCTGG CCTGCAGCAC
GAGATCCTCC GGAGAGTCCA GGAACTGCTG GATGCAGCCA GGATCCAGCC AGAGCTGAAA
CCACCAATGG GTGAGGTCGT CACCCCTACG GCCCCCCAGG AGCCTCCTGA GTCTGTGAGG
CCATCCGCTC CCCCTGCAGA GCTGGAGGTG CAGGCCTCAG AGTGTGTCGT GTGCCTGGAA
CGGGAGGCCC AGATGATCTT CCTCAACTGT GGCCACGTCT GCTGCTGCCA GCAGTGCTGC
CAGCCACTGC GCACCTGCCC GCTGTGCCGC CAGGACATCG CCCAGCGCCT CCGCATCTAC
CACAGCAGCT GA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq NP_001005373.1
CDS373..2544
Misc Feature(1)346..348
Misc Feature(2)460..525
Misc Feature(3)469..534
Misc Feature(4)535..618
Misc Feature(5)538..603
Misc Feature(6)544..720
Misc Feature(7)<571..858
Misc Feature(8)616..681
Misc Feature(9)619..687
Misc Feature(10)685..753
Misc Feature(11)688..756
Misc Feature(12)751..915
Misc Feature(13)751..870
Misc Feature(14)754..819
Misc Feature(15)757..825
Misc Feature(16)823..888
Misc Feature(17)1072..1074
Misc Feature(18)<1294..1620
Misc Feature(19)2071..2265
Misc Feature(20)2083..2265
Misc Feature(21)2182..2184
Misc Feature(22)2317..2328
Misc Feature(23)2353..2364
Misc Feature(24)2392..2520
Exon (1)1..184
Exon (2)185..340
Exon (3)341..444
Exon (4)445..501
Exon (5)502..546
Exon (6)547..624
Exon (7)625..693
Exon (8)694..778
Exon (9)779..900
Exon (10)901..991
Exon (11)992..1122
Exon (12)1123..1152
Exon (13)1153..1275
Exon (14)1276..1415
Exon (15)1416..1460
Exon (16)1461..1531
Exon (17)1532..1631
Exon (18)1632..1719
Exon (19)1720..1794
Exon (20)1795..1875
Exon (21)1876..1971
Exon (22)1972..2070
Exon (23)2071..2202
Exon (24)2203..2284
Exon (25)2285..2418
Exon (26)2419..3146
Translation

Target ORF information:

RefSeq Version NM_001005373.3
Organism Homo sapiens(Human)
Definition Homo sapiens leucine rich repeat and sterile alpha motif containing 1 (LRSAM1), transcript variant 2, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
NM_001005373.3

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
1501
1561
1621
1681
1741
1801
1861
1921
1981
2041
2101
2161
ATGCCGCTCT TCTTCCGGAA GCGGAAACCC AGTGAGGAGG CTCGGAAACG CCTGGAGTAC 
CAGATGTGTT TGGCAAAAGA AGCTGGGGCA GATGACATTC TCGACATCTC TAAATGTGAG
CTCTCAGAGA TTCCATTTGG AGCTTTTGCA ACATGCAAAG TTCTGCAGAA GAAGGTGCTG
ATCGTCCACA CGAATCACCT CACTTCCCTG CTTCCCAAAT CCTGCAGCCT CCTGAGTCTG
GCAACCATCA AGGTTCTAGA TCTCCACGAT AATCAGCTGA CAGCCCTTCC TGACGATCTG
GGGCAGCTGA CTGCCCTCCA GGTCTTAAAC GTGGAAAGGA ATCAACTGAT GCAGCTCCCA
CGTTCCATTG GGAACCTGAC CCAGCTCCAG ACTCTCAATG TTAAAGACAA CAAGCTGAAG
GAGCTTCCAG ACACCGTGGG GGAGCTTCGA AGCCTGCGTA CCCTCAACAT CAGTGGAAAC
GAGATCCAGA GATTGCCGCA GATGCTGGCT CACGTTCGAA CCCTGGAGAT GCTGAGCCTT
GACGCCTCGG CCATGGTCTA CCCGCCGCGG GAGGTGTGTG GTGCCGGCAC TGCGGCCATC
TTGCAGTTCC TCTGCAAAGA GTCAGGGCTG GAATACTACC CCCCTTCTCA GTACTTGCTG
CCAATTCTGG AGCAAGATGG AATCGAGAAC TCTCGGGACA GCCCTGATGG GCCCACGGAC
AGATTCTCAA GGGAGGAGTT AGAGTGGCAG AACAGGTTCT CAGACTATGA GAAGAGGAAG
GAACAGAAGA TGCTGGAGAA ACTCGAGTTT GAACGGCGCC TGGAACTGGG GCAGCGGGAG
CACACCCAGC TCCTTCAGCA GAGCAGCAGC CAGAAGGATG AGATCCTTCA GACGGTCAAG
GAGGAGCAGT CCCGGCTGGA GCAGGGCCTG AGTGAGCACC AGCGCCACCT CAACGCAGAG
CGGCAGCGGC TGCAGGAGCA GCTGAAGCAG ACGGAACAGA ACATTTCCAG CCGGATCCAG
AAGCTGCTGC AGGACAATCA GAGACAAAAG AAAAGCTCCG AGATTTTGAA ATCGCTGGAA
AATGAAAGAA TAAGAATGGA ACAGTTGATG TCCATAACCC AGGAGGAGAC TGAGAGCCTG
CGGCGACGTG ACGTTGCCTC CGCCATGCAG CAGATGCTGA CTGAGAGCTG TAAGAACCGG
CTCATCCAGA TGGCCTACGA ATCTCAGAGG CAGAACTTGG TCCAGCAGGC CTGTTCCAGC
ATGGCCGAAA TGGATGAACG ATTCCAGCAG ATTCTGTCGT GGCAGCAAAT GGATCAGAAC
AAAGCCATCA GCCAGATCCT GCAGGAGAGC GCGATGCAGA AGGCTGCGTT CGAGGCACTC
CAGGTGAAGA AAGACCTGAT GCATCGGCAG ATCAGGAGCC AGATTAAGTT AATAGAAACT
GAGTTATTGC AGCTGACACA GCTGGAGTTA AAGAGGAAGT CCCTGGACAC AGAGTCACTC
CAGGAGATGA TCTCGGAGCA GCGCTGGGCC CTCAGCTCCC TGCTCCAGCA GCTGCTCAAA
GAGAAGCAGC AGCGAGAGGA AGAGCTCCGG GAAATCCTGA CGGAGTTAGA AGCCAAAAGT
GAAACCAGGC AGGAAAATTA CTGGCTGATT CAGTATCAAC GGCTTTTGAA CCAGAAGCCC
TTGTCCTTGA AGCTGCAAGA AGAGGGGATG GAGCGCCAGC TGGTGGCCCT CCTGGAGGAG
CTGTCGGCTG AGCACTACCT GCCCATCTTT GCGCACCACC GCCTCTCACT GGACCTGCTG
AGCCAAATGA GCCCAGGGGA CCTGGCCAAG GTGGGCGTCT CAGAAGCTGG CCTGCAGCAC
GAGATCCTCC GGAGAGTCCA GGAACTGCTG GATGCAGCCA GGATCCAGCC AGAGCTGAAA
CCACCAATGG GTGAGGTCGT CACCCCTACG GCCCCCCAGG AGCCTCCTGA GTCTGTGAGG
CCATCCGCTC CCCCTGCAGA GCTGGAGGTG CAGGCCTCAG AGTGTGTCGT GTGCCTGGAA
CGGGAGGCCC AGATGATCTT CCTCAACTGT GGCCACGTCT GCTGCTGCCA GCAGTGCTGC
CAGCCACTGC GCACCTGCCC GCTGTGCCGC CAGGACATCG CCCAGCGCCT CCGCATCTAC
CACAGCAGCT GA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OHu26634
Clone ID Related Accession (Same CDS sequence) NM_001005373.3 , NM_138361.5 , XM_017015283.1 , NM_001005374.3
Accession Version NM_138361.5 Latest version! Documents for ORF clone product in dufault vector
Sequence Information ORF Nucleotide Sequence (Length: 2172bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ® Seamless cloning technology
Insert Structure linear
Update Date 2017-03-19
Organism Homo sapiens(Human)
Product E3 ubiquitin-protein ligase LRSAM1 isoform 1
Comment REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from DA726792.1, AK091589.1, BC009239.2 and AI364608.1. This sequence is a reference standard in the RefSeqGene project. On Jan 14, 2012 this sequence version replaced NM_138361.4. Transcript Variant: This variant (1) represents the longest transcript and encodes the longer isoform (1). Variants 1, 2 and 3 encode the same isoform (1). Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AK091589.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
1501
1561
1621
1681
1741
1801
1861
1921
1981
2041
2101
2161
ATGCCGCTCT TCTTCCGGAA GCGGAAACCC AGTGAGGAGG CTCGGAAACG CCTGGAGTAC 
CAGATGTGTT TGGCAAAAGA AGCTGGGGCA GATGACATTC TCGACATCTC TAAATGTGAG
CTCTCAGAGA TTCCATTTGG AGCTTTTGCA ACATGCAAAG TTCTGCAGAA GAAGGTGCTG
ATCGTCCACA CGAATCACCT CACTTCCCTG CTTCCCAAAT CCTGCAGCCT CCTGAGTCTG
GCAACCATCA AGGTTCTAGA TCTCCACGAT AATCAGCTGA CAGCCCTTCC TGACGATCTG
GGGCAGCTGA CTGCCCTCCA GGTCTTAAAC GTGGAAAGGA ATCAACTGAT GCAGCTCCCA
CGTTCCATTG GGAACCTGAC CCAGCTCCAG ACTCTCAATG TTAAAGACAA CAAGCTGAAG
GAGCTTCCAG ACACCGTGGG GGAGCTTCGA AGCCTGCGTA CCCTCAACAT CAGTGGAAAC
GAGATCCAGA GATTGCCGCA GATGCTGGCT CACGTTCGAA CCCTGGAGAT GCTGAGCCTT
GACGCCTCGG CCATGGTCTA CCCGCCGCGG GAGGTGTGTG GTGCCGGCAC TGCGGCCATC
TTGCAGTTCC TCTGCAAAGA GTCAGGGCTG GAATACTACC CCCCTTCTCA GTACTTGCTG
CCAATTCTGG AGCAAGATGG AATCGAGAAC TCTCGGGACA GCCCTGATGG GCCCACGGAC
AGATTCTCAA GGGAGGAGTT AGAGTGGCAG AACAGGTTCT CAGACTATGA GAAGAGGAAG
GAACAGAAGA TGCTGGAGAA ACTCGAGTTT GAACGGCGCC TGGAACTGGG GCAGCGGGAG
CACACCCAGC TCCTTCAGCA GAGCAGCAGC CAGAAGGATG AGATCCTTCA GACGGTCAAG
GAGGAGCAGT CCCGGCTGGA GCAGGGCCTG AGTGAGCACC AGCGCCACCT CAACGCAGAG
CGGCAGCGGC TGCAGGAGCA GCTGAAGCAG ACGGAACAGA ACATTTCCAG CCGGATCCAG
AAGCTGCTGC AGGACAATCA GAGACAAAAG AAAAGCTCCG AGATTTTGAA ATCGCTGGAA
AATGAAAGAA TAAGAATGGA ACAGTTGATG TCCATAACCC AGGAGGAGAC TGAGAGCCTG
CGGCGACGTG ACGTTGCCTC CGCCATGCAG CAGATGCTGA CTGAGAGCTG TAAGAACCGG
CTCATCCAGA TGGCCTACGA ATCTCAGAGG CAGAACTTGG TCCAGCAGGC CTGTTCCAGC
ATGGCCGAAA TGGATGAACG ATTCCAGCAG ATTCTGTCGT GGCAGCAAAT GGATCAGAAC
AAAGCCATCA GCCAGATCCT GCAGGAGAGC GCGATGCAGA AGGCTGCGTT CGAGGCACTC
CAGGTGAAGA AAGACCTGAT GCATCGGCAG ATCAGGAGCC AGATTAAGTT AATAGAAACT
GAGTTATTGC AGCTGACACA GCTGGAGTTA AAGAGGAAGT CCCTGGACAC AGAGTCACTC
CAGGAGATGA TCTCGGAGCA GCGCTGGGCC CTCAGCTCCC TGCTCCAGCA GCTGCTCAAA
GAGAAGCAGC AGCGAGAGGA AGAGCTCCGG GAAATCCTGA CGGAGTTAGA AGCCAAAAGT
GAAACCAGGC AGGAAAATTA CTGGCTGATT CAGTATCAAC GGCTTTTGAA CCAGAAGCCC
TTGTCCTTGA AGCTGCAAGA AGAGGGGATG GAGCGCCAGC TGGTGGCCCT CCTGGAGGAG
CTGTCGGCTG AGCACTACCT GCCCATCTTT GCGCACCACC GCCTCTCACT GGACCTGCTG
AGCCAAATGA GCCCAGGGGA CCTGGCCAAG GTGGGCGTCT CAGAAGCTGG CCTGCAGCAC
GAGATCCTCC GGAGAGTCCA GGAACTGCTG GATGCAGCCA GGATCCAGCC AGAGCTGAAA
CCACCAATGG GTGAGGTCGT CACCCCTACG GCCCCCCAGG AGCCTCCTGA GTCTGTGAGG
CCATCCGCTC CCCCTGCAGA GCTGGAGGTG CAGGCCTCAG AGTGTGTCGT GTGCCTGGAA
CGGGAGGCCC AGATGATCTT CCTCAACTGT GGCCACGTCT GCTGCTGCCA GCAGTGCTGC
CAGCCACTGC GCACCTGCCC GCTGTGCCGC CAGGACATCG CCCAGCGCCT CCGCATCTAC
CACAGCAGCT GA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq NP_612370.3
CDS632..2803
Misc Feature(1)605..607
Misc Feature(2)719..784
Misc Feature(3)728..793
Misc Feature(4)794..877
Misc Feature(5)797..862
Misc Feature(6)803..979
Misc Feature(7)<830..1117
Misc Feature(8)875..940
Misc Feature(9)878..946
Misc Feature(10)944..1012
Misc Feature(11)947..1015
Misc Feature(12)1010..1174
Misc Feature(13)1010..1129
Misc Feature(14)1013..1078
Misc Feature(15)1016..1084
Misc Feature(16)1082..1147
Misc Feature(17)1331..1333
Misc Feature(18)<1553..1879
Misc Feature(19)2330..2524
Misc Feature(20)2342..2524
Misc Feature(21)2441..2443
Misc Feature(22)2576..2587
Misc Feature(23)2612..2623
Misc Feature(24)2651..2779
Exon (1)1..599
Exon (2)600..703
Exon (3)704..760
Exon (4)761..805
Exon (5)806..883
Exon (6)884..952
Exon (7)953..1037
Exon (8)1038..1159
Exon (9)1160..1250
Exon (10)1251..1381
Exon (11)1382..1411
Exon (12)1412..1534
Exon (13)1535..1674
Exon (14)1675..1719
Exon (15)1720..1790
Exon (16)1791..1890
Exon (17)1891..1978
Exon (18)1979..2053
Exon (19)2054..2134
Exon (20)2135..2230
Exon (21)2231..2329
Exon (22)2330..2461
Exon (23)2462..2543
Exon (24)2544..2677
Exon (25)2678..3405
Translation

Target ORF information:

RefSeq Version NM_138361.5
Organism Homo sapiens(Human)
Definition Homo sapiens leucine rich repeat and sterile alpha motif containing 1 (LRSAM1), transcript variant 1, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
NM_138361.5

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
1501
1561
1621
1681
1741
1801
1861
1921
1981
2041
2101
2161
ATGCCGCTCT TCTTCCGGAA GCGGAAACCC AGTGAGGAGG CTCGGAAACG CCTGGAGTAC 
CAGATGTGTT TGGCAAAAGA AGCTGGGGCA GATGACATTC TCGACATCTC TAAATGTGAG
CTCTCAGAGA TTCCATTTGG AGCTTTTGCA ACATGCAAAG TTCTGCAGAA GAAGGTGCTG
ATCGTCCACA CGAATCACCT CACTTCCCTG CTTCCCAAAT CCTGCAGCCT CCTGAGTCTG
GCAACCATCA AGGTTCTAGA TCTCCACGAT AATCAGCTGA CAGCCCTTCC TGACGATCTG
GGGCAGCTGA CTGCCCTCCA GGTCTTAAAC GTGGAAAGGA ATCAACTGAT GCAGCTCCCA
CGTTCCATTG GGAACCTGAC CCAGCTCCAG ACTCTCAATG TTAAAGACAA CAAGCTGAAG
GAGCTTCCAG ACACCGTGGG GGAGCTTCGA AGCCTGCGTA CCCTCAACAT CAGTGGAAAC
GAGATCCAGA GATTGCCGCA GATGCTGGCT CACGTTCGAA CCCTGGAGAT GCTGAGCCTT
GACGCCTCGG CCATGGTCTA CCCGCCGCGG GAGGTGTGTG GTGCCGGCAC TGCGGCCATC
TTGCAGTTCC TCTGCAAAGA GTCAGGGCTG GAATACTACC CCCCTTCTCA GTACTTGCTG
CCAATTCTGG AGCAAGATGG AATCGAGAAC TCTCGGGACA GCCCTGATGG GCCCACGGAC
AGATTCTCAA GGGAGGAGTT AGAGTGGCAG AACAGGTTCT CAGACTATGA GAAGAGGAAG
GAACAGAAGA TGCTGGAGAA ACTCGAGTTT GAACGGCGCC TGGAACTGGG GCAGCGGGAG
CACACCCAGC TCCTTCAGCA GAGCAGCAGC CAGAAGGATG AGATCCTTCA GACGGTCAAG
GAGGAGCAGT CCCGGCTGGA GCAGGGCCTG AGTGAGCACC AGCGCCACCT CAACGCAGAG
CGGCAGCGGC TGCAGGAGCA GCTGAAGCAG ACGGAACAGA ACATTTCCAG CCGGATCCAG
AAGCTGCTGC AGGACAATCA GAGACAAAAG AAAAGCTCCG AGATTTTGAA ATCGCTGGAA
AATGAAAGAA TAAGAATGGA ACAGTTGATG TCCATAACCC AGGAGGAGAC TGAGAGCCTG
CGGCGACGTG ACGTTGCCTC CGCCATGCAG CAGATGCTGA CTGAGAGCTG TAAGAACCGG
CTCATCCAGA TGGCCTACGA ATCTCAGAGG CAGAACTTGG TCCAGCAGGC CTGTTCCAGC
ATGGCCGAAA TGGATGAACG ATTCCAGCAG ATTCTGTCGT GGCAGCAAAT GGATCAGAAC
AAAGCCATCA GCCAGATCCT GCAGGAGAGC GCGATGCAGA AGGCTGCGTT CGAGGCACTC
CAGGTGAAGA AAGACCTGAT GCATCGGCAG ATCAGGAGCC AGATTAAGTT AATAGAAACT
GAGTTATTGC AGCTGACACA GCTGGAGTTA AAGAGGAAGT CCCTGGACAC AGAGTCACTC
CAGGAGATGA TCTCGGAGCA GCGCTGGGCC CTCAGCTCCC TGCTCCAGCA GCTGCTCAAA
GAGAAGCAGC AGCGAGAGGA AGAGCTCCGG GAAATCCTGA CGGAGTTAGA AGCCAAAAGT
GAAACCAGGC AGGAAAATTA CTGGCTGATT CAGTATCAAC GGCTTTTGAA CCAGAAGCCC
TTGTCCTTGA AGCTGCAAGA AGAGGGGATG GAGCGCCAGC TGGTGGCCCT CCTGGAGGAG
CTGTCGGCTG AGCACTACCT GCCCATCTTT GCGCACCACC GCCTCTCACT GGACCTGCTG
AGCCAAATGA GCCCAGGGGA CCTGGCCAAG GTGGGCGTCT CAGAAGCTGG CCTGCAGCAC
GAGATCCTCC GGAGAGTCCA GGAACTGCTG GATGCAGCCA GGATCCAGCC AGAGCTGAAA
CCACCAATGG GTGAGGTCGT CACCCCTACG GCCCCCCAGG AGCCTCCTGA GTCTGTGAGG
CCATCCGCTC CCCCTGCAGA GCTGGAGGTG CAGGCCTCAG AGTGTGTCGT GTGCCTGGAA
CGGGAGGCCC AGATGATCTT CCTCAACTGT GGCCACGTCT GCTGCTGCCA GCAGTGCTGC
CAGCCACTGC GCACCTGCCC GCTGTGCCGC CAGGACATCG CCCAGCGCCT CCGCATCTAC
CACAGCAGCT GA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OHu26634
Clone ID Related Accession (Same CDS sequence) NM_001005373.3 , NM_138361.5 , XM_017015283.1 , NM_001005374.3
Accession Version NM_001005374.3 Latest version! Documents for ORF clone product in dufault vector
Sequence Information ORF Nucleotide Sequence (Length: 2172bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ® Seamless cloning technology
Insert Structure linear
Update Date 2017-03-19
Organism Homo sapiens(Human)
Product E3 ubiquitin-protein ligase LRSAM1 isoform 1
Comment REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from BC009239.2, AY358830.1 and AI364608.1. On Jan 14, 2012 this sequence version replaced NM_001005374.2. Transcript Variant: This variant (3) differs in the 5' UTR compared to variant 1. Variants 1, 2 and 3 encode the same isoform (1). Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC009239.2 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2155974 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
1501
1561
1621
1681
1741
1801
1861
1921
1981
2041
2101
2161
ATGCCGCTCT TCTTCCGGAA GCGGAAACCC AGTGAGGAGG CTCGGAAACG CCTGGAGTAC 
CAGATGTGTT TGGCAAAAGA AGCTGGGGCA GATGACATTC TCGACATCTC TAAATGTGAG
CTCTCAGAGA TTCCATTTGG AGCTTTTGCA ACATGCAAAG TTCTGCAGAA GAAGGTGCTG
ATCGTCCACA CGAATCACCT CACTTCCCTG CTTCCCAAAT CCTGCAGCCT CCTGAGTCTG
GCAACCATCA AGGTTCTAGA TCTCCACGAT AATCAGCTGA CAGCCCTTCC TGACGATCTG
GGGCAGCTGA CTGCCCTCCA GGTCTTAAAC GTGGAAAGGA ATCAACTGAT GCAGCTCCCA
CGTTCCATTG GGAACCTGAC CCAGCTCCAG ACTCTCAATG TTAAAGACAA CAAGCTGAAG
GAGCTTCCAG ACACCGTGGG GGAGCTTCGA AGCCTGCGTA CCCTCAACAT CAGTGGAAAC
GAGATCCAGA GATTGCCGCA GATGCTGGCT CACGTTCGAA CCCTGGAGAT GCTGAGCCTT
GACGCCTCGG CCATGGTCTA CCCGCCGCGG GAGGTGTGTG GTGCCGGCAC TGCGGCCATC
TTGCAGTTCC TCTGCAAAGA GTCAGGGCTG GAATACTACC CCCCTTCTCA GTACTTGCTG
CCAATTCTGG AGCAAGATGG AATCGAGAAC TCTCGGGACA GCCCTGATGG GCCCACGGAC
AGATTCTCAA GGGAGGAGTT AGAGTGGCAG AACAGGTTCT CAGACTATGA GAAGAGGAAG
GAACAGAAGA TGCTGGAGAA ACTCGAGTTT GAACGGCGCC TGGAACTGGG GCAGCGGGAG
CACACCCAGC TCCTTCAGCA GAGCAGCAGC CAGAAGGATG AGATCCTTCA GACGGTCAAG
GAGGAGCAGT CCCGGCTGGA GCAGGGCCTG AGTGAGCACC AGCGCCACCT CAACGCAGAG
CGGCAGCGGC TGCAGGAGCA GCTGAAGCAG ACGGAACAGA ACATTTCCAG CCGGATCCAG
AAGCTGCTGC AGGACAATCA GAGACAAAAG AAAAGCTCCG AGATTTTGAA ATCGCTGGAA
AATGAAAGAA TAAGAATGGA ACAGTTGATG TCCATAACCC AGGAGGAGAC TGAGAGCCTG
CGGCGACGTG ACGTTGCCTC CGCCATGCAG CAGATGCTGA CTGAGAGCTG TAAGAACCGG
CTCATCCAGA TGGCCTACGA ATCTCAGAGG CAGAACTTGG TCCAGCAGGC CTGTTCCAGC
ATGGCCGAAA TGGATGAACG ATTCCAGCAG ATTCTGTCGT GGCAGCAAAT GGATCAGAAC
AAAGCCATCA GCCAGATCCT GCAGGAGAGC GCGATGCAGA AGGCTGCGTT CGAGGCACTC
CAGGTGAAGA AAGACCTGAT GCATCGGCAG ATCAGGAGCC AGATTAAGTT AATAGAAACT
GAGTTATTGC AGCTGACACA GCTGGAGTTA AAGAGGAAGT CCCTGGACAC AGAGTCACTC
CAGGAGATGA TCTCGGAGCA GCGCTGGGCC CTCAGCTCCC TGCTCCAGCA GCTGCTCAAA
GAGAAGCAGC AGCGAGAGGA AGAGCTCCGG GAAATCCTGA CGGAGTTAGA AGCCAAAAGT
GAAACCAGGC AGGAAAATTA CTGGCTGATT CAGTATCAAC GGCTTTTGAA CCAGAAGCCC
TTGTCCTTGA AGCTGCAAGA AGAGGGGATG GAGCGCCAGC TGGTGGCCCT CCTGGAGGAG
CTGTCGGCTG AGCACTACCT GCCCATCTTT GCGCACCACC GCCTCTCACT GGACCTGCTG
AGCCAAATGA GCCCAGGGGA CCTGGCCAAG GTGGGCGTCT CAGAAGCTGG CCTGCAGCAC
GAGATCCTCC GGAGAGTCCA GGAACTGCTG GATGCAGCCA GGATCCAGCC AGAGCTGAAA
CCACCAATGG GTGAGGTCGT CACCCCTACG GCCCCCCAGG AGCCTCCTGA GTCTGTGAGG
CCATCCGCTC CCCCTGCAGA GCTGGAGGTG CAGGCCTCAG AGTGTGTCGT GTGCCTGGAA
CGGGAGGCCC AGATGATCTT CCTCAACTGT GGCCACGTCT GCTGCTGCCA GCAGTGCTGC
CAGCCACTGC GCACCTGCCC GCTGTGCCGC CAGGACATCG CCCAGCGCCT CCGCATCTAC
CACAGCAGCT GA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq NP_001005374.1
CDS78..2249
Misc Feature(1)51..53
Misc Feature(2)165..230
Misc Feature(3)174..239
Misc Feature(4)240..323
Misc Feature(5)243..308
Misc Feature(6)249..425
Misc Feature(7)<276..563
Misc Feature(8)321..386
Misc Feature(9)324..392
Misc Feature(10)390..458
Misc Feature(11)393..461
Misc Feature(12)456..620
Misc Feature(13)456..575
Misc Feature(14)459..524
Misc Feature(15)462..530
Misc Feature(16)528..593
Misc Feature(17)777..779
Misc Feature(18)<999..1325
Misc Feature(19)1776..1970
Misc Feature(20)1788..1970
Misc Feature(21)1887..1889
Misc Feature(22)2022..2033
Misc Feature(23)2058..2069
Misc Feature(24)2097..2225
Exon (1)1..45
Exon (2)46..149
Exon (3)150..206
Exon (4)207..251
Exon (5)252..329
Exon (6)330..398
Exon (7)399..483
Exon (8)484..605
Exon (9)606..696
Exon (10)697..827
Exon (11)828..857
Exon (12)858..980
Exon (13)981..1120
Exon (14)1121..1165
Exon (15)1166..1236
Exon (16)1237..1336
Exon (17)1337..1424
Exon (18)1425..1499
Exon (19)1500..1580
Exon (20)1581..1676
Exon (21)1677..1775
Exon (22)1776..1907
Exon (23)1908..1989
Exon (24)1990..2123
Exon (25)2124..2851
Translation

Target ORF information:

RefSeq Version NM_001005374.3
Organism Homo sapiens(Human)
Definition Homo sapiens leucine rich repeat and sterile alpha motif containing 1 (LRSAM1), transcript variant 3, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
NM_001005374.3

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
1501
1561
1621
1681
1741
1801
1861
1921
1981
2041
2101
2161
ATGCCGCTCT TCTTCCGGAA GCGGAAACCC AGTGAGGAGG CTCGGAAACG CCTGGAGTAC 
CAGATGTGTT TGGCAAAAGA AGCTGGGGCA GATGACATTC TCGACATCTC TAAATGTGAG
CTCTCAGAGA TTCCATTTGG AGCTTTTGCA ACATGCAAAG TTCTGCAGAA GAAGGTGCTG
ATCGTCCACA CGAATCACCT CACTTCCCTG CTTCCCAAAT CCTGCAGCCT CCTGAGTCTG
GCAACCATCA AGGTTCTAGA TCTCCACGAT AATCAGCTGA CAGCCCTTCC TGACGATCTG
GGGCAGCTGA CTGCCCTCCA GGTCTTAAAC GTGGAAAGGA ATCAACTGAT GCAGCTCCCA
CGTTCCATTG GGAACCTGAC CCAGCTCCAG ACTCTCAATG TTAAAGACAA CAAGCTGAAG
GAGCTTCCAG ACACCGTGGG GGAGCTTCGA AGCCTGCGTA CCCTCAACAT CAGTGGAAAC
GAGATCCAGA GATTGCCGCA GATGCTGGCT CACGTTCGAA CCCTGGAGAT GCTGAGCCTT
GACGCCTCGG CCATGGTCTA CCCGCCGCGG GAGGTGTGTG GTGCCGGCAC TGCGGCCATC
TTGCAGTTCC TCTGCAAAGA GTCAGGGCTG GAATACTACC CCCCTTCTCA GTACTTGCTG
CCAATTCTGG AGCAAGATGG AATCGAGAAC TCTCGGGACA GCCCTGATGG GCCCACGGAC
AGATTCTCAA GGGAGGAGTT AGAGTGGCAG AACAGGTTCT CAGACTATGA GAAGAGGAAG
GAACAGAAGA TGCTGGAGAA ACTCGAGTTT GAACGGCGCC TGGAACTGGG GCAGCGGGAG
CACACCCAGC TCCTTCAGCA GAGCAGCAGC CAGAAGGATG AGATCCTTCA GACGGTCAAG
GAGGAGCAGT CCCGGCTGGA GCAGGGCCTG AGTGAGCACC AGCGCCACCT CAACGCAGAG
CGGCAGCGGC TGCAGGAGCA GCTGAAGCAG ACGGAACAGA ACATTTCCAG CCGGATCCAG
AAGCTGCTGC AGGACAATCA GAGACAAAAG AAAAGCTCCG AGATTTTGAA ATCGCTGGAA
AATGAAAGAA TAAGAATGGA ACAGTTGATG TCCATAACCC AGGAGGAGAC TGAGAGCCTG
CGGCGACGTG ACGTTGCCTC CGCCATGCAG CAGATGCTGA CTGAGAGCTG TAAGAACCGG
CTCATCCAGA TGGCCTACGA ATCTCAGAGG CAGAACTTGG TCCAGCAGGC CTGTTCCAGC
ATGGCCGAAA TGGATGAACG ATTCCAGCAG ATTCTGTCGT GGCAGCAAAT GGATCAGAAC
AAAGCCATCA GCCAGATCCT GCAGGAGAGC GCGATGCAGA AGGCTGCGTT CGAGGCACTC
CAGGTGAAGA AAGACCTGAT GCATCGGCAG ATCAGGAGCC AGATTAAGTT AATAGAAACT
GAGTTATTGC AGCTGACACA GCTGGAGTTA AAGAGGAAGT CCCTGGACAC AGAGTCACTC
CAGGAGATGA TCTCGGAGCA GCGCTGGGCC CTCAGCTCCC TGCTCCAGCA GCTGCTCAAA
GAGAAGCAGC AGCGAGAGGA AGAGCTCCGG GAAATCCTGA CGGAGTTAGA AGCCAAAAGT
GAAACCAGGC AGGAAAATTA CTGGCTGATT CAGTATCAAC GGCTTTTGAA CCAGAAGCCC
TTGTCCTTGA AGCTGCAAGA AGAGGGGATG GAGCGCCAGC TGGTGGCCCT CCTGGAGGAG
CTGTCGGCTG AGCACTACCT GCCCATCTTT GCGCACCACC GCCTCTCACT GGACCTGCTG
AGCCAAATGA GCCCAGGGGA CCTGGCCAAG GTGGGCGTCT CAGAAGCTGG CCTGCAGCAC
GAGATCCTCC GGAGAGTCCA GGAACTGCTG GATGCAGCCA GGATCCAGCC AGAGCTGAAA
CCACCAATGG GTGAGGTCGT CACCCCTACG GCCCCCCAGG AGCCTCCTGA GTCTGTGAGG
CCATCCGCTC CCCCTGCAGA GCTGGAGGTG CAGGCCTCAG AGTGTGTCGT GTGCCTGGAA
CGGGAGGCCC AGATGATCTT CCTCAACTGT GGCCACGTCT GCTGCTGCCA GCAGTGCTGC
CAGCCACTGC GCACCTGCCC GCTGTGCCGC CAGGACATCG CCCAGCGCCT CCGCATCTAC
CACAGCAGCT GA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OHu26960
Clone ID Related Accession (Same CDS sequence) NM_001190723.2
Accession Version NM_001190723.2 Latest version! Documents for ORF clone product in dufault vector
Sequence Information ORF Nucleotide Sequence (Length: 2091bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ® Seamless cloning technology
Insert Structure linear
Update Date 2017-03-19
Organism Homo sapiens(Human)
Product E3 ubiquitin-protein ligase LRSAM1 isoform 2
Comment REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from DA165729.1, AK056203.1, BC009239.2 and DB309230.1. On Jan 14, 2012 this sequence version replaced NM_001190723.1. Transcript Variant: This variant (4) lacks an in-frame exon in the coding region, compared to variant 1. The encoded isoform (2) is shorter than isoform 1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AK056203.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1968540, SAMEA2142348 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
1501
1561
1621
1681
1741
1801
1861
1921
1981
2041
ATGCCGCTCT TCTTCCGGAA GCGGAAACCC AGTGAGGAGG CTCGGAAACG CCTGGAGTAC 
CAGATGTGTT TGGCAAAAGA AGCTGGGGCA GATGACATTC TCGACATCTC TAAATGTGAG
CTCTCAGAGA TTCCATTTGG AGCTTTTGCA ACATGCAAAG TTCTGCAGAA GAAGGTGCTG
ATCGTCCACA CGAATCACCT CACTTCCCTG CTTCCCAAAT CCTGCAGCCT CCTGAGTCTG
GCAACCATCA AGGTTCTAGA TCTCCACGAT AATCAGCTGA CAGCCCTTCC TGACGATCTG
GGGCAGCTGA CTGCCCTCCA GGTCTTAAAC GTGGAAAGGA ATCAACTGAT GCAGCTCCCA
CGTTCCATTG GGAACCTGAC CCAGCTCCAG ACTCTCAATG TTAAAGACAA CAAGCTGAAG
GAGCTTCCAG ACACCGTGGG GGAGCTTCGA AGCCTGCGTA CCCTCAACAT CAGTGGAAAC
GAGATCCAGA GATTGCCGCA GATGCTGGCT CACGTTCGAA CCCTGGAGAT GCTGAGCCTT
GACGCCTCGG CCATGGTCTA CCCGCCGCGG GAGGTGTGTG GTGCCGGCAC TGCGGCCATC
TTGCAGTTCC TCTGCAAAGA GTCAGGGCTG GAATACTACC CCCCTTCTCA GTACTTGCTG
CCAATTCTGG AGCAAGATGG AATCGAGAAC TCTCGGGACA GCCCTGATGG GCCCACGGAC
AGATTCTCAA GGGAGGAGTT AGAGTGGCAG AACAGGTTCT CAGACTATGA GAAGAGGAAG
GAACAGAAGA TGCTGGAGAA ACTCGAGTTT GAACGGCGCC TGGAACTGGG GCAGCGGGAG
CACACCCAGC TCCTTCAGCA GAGCAGCAGC CAGAAGGATG AGATCCTTCA GACGGTCAAG
GAGGAGCAGT CCCGGCTGGA GCAGGGCCTG AGTGAGCACC AGCGCCACCT CAACGCAGAG
CGGCAGCGGC TGCAGGAGCA GCTGAAGCAG ACGGAACAGA ACATTTCCAG CCGGATCCAG
AAGCTGCTGC AGGACAATCA GAGACAAAAG AAAAGCTCCG AGATTTTGAA ATCGCTGGAA
AATGAAAGAA TAAGAATGGA ACAGTTGATG TCCATAACCC AGGAGGAGAC TGAGAGCCTG
CGGCGACGTG ACGTTGCCTC CGCCATGCAG CAGATGCTGA CTGAGAGCTG TAAGAACCGG
CTCATCCAGA TGGCCTACGA ATCTCAGAGG CAGAACTTGG TCCAGCAGGC CTGTTCCAGC
ATGGCCGAAA TGGATGAACG ATTCCAGCAG ATTCTGTCGT GGCAGCAAAT GGATCAGAAC
AAAGCCATCA GCCAGATCCT GCAGGAGAGC GCGATGCAGA AGGCTGCGTT CGAGGCACTC
CAGGTGAAGA AAGACCTGAT GCATCGGCAG ATCAGGAGCC AGGAGATGAT CTCGGAGCAG
CGCTGGGCCC TCAGCTCCCT GCTCCAGCAG CTGCTCAAAG AGAAGCAGCA GCGAGAGGAA
GAGCTCCGGG AAATCCTGAC GGAGTTAGAA GCCAAAAGTG AAACCAGGCA GGAAAATTAC
TGGCTGATTC AGTATCAACG GCTTTTGAAC CAGAAGCCCT TGTCCTTGAA GCTGCAAGAA
GAGGGGATGG AGCGCCAGCT GGTGGCCCTC CTGGAGGAGC TGTCGGCTGA GCACTACCTG
CCCATCTTTG CGCACCACCG CCTCTCACTG GACCTGCTGA GCCAAATGAG CCCAGGGGAC
CTGGCCAAGG TGGGCGTCTC AGAAGCTGGC CTGCAGCACG AGATCCTCCG GAGAGTCCAG
GAACTGCTGG ATGCAGCCAG GATCCAGCCA GAGCTGAAAC CACCAATGGG TGAGGTCGTC
ACCCCTACGG CCCCCCAGGA GCCTCCTGAG TCTGTGAGGC CATCCGCTCC CCCTGCAGAG
CTGGAGGTGC AGGCCTCAGA GTGTGTCGTG TGCCTGGAAC GGGAGGCCCA GATGATCTTC
CTCAACTGTG GCCACGTCTG CTGCTGCCAG CAGTGCTGCC AGCCACTGCG CACCTGCCCG
CTGTGCCGCC AGGACATCGC CCAGCGCCTC CGCATCTACC ACAGCAGCTG A

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq NP_001177652.1
CDS373..2463
Misc Feature(1)346..348
Misc Feature(2)469..534
Misc Feature(3)535..618
Misc Feature(4)544..720
Misc Feature(5)<571..858
Misc Feature(6)619..687
Misc Feature(7)688..756
Misc Feature(8)751..915
Misc Feature(9)751..870
Misc Feature(10)757..825
Misc Feature(11)<1294..1620
Misc Feature(12)1990..2184
Misc Feature(13)2002..2184
Misc Feature(14)2311..2439
Exon (1)1..184
Exon (2)185..340
Exon (3)341..444
Exon (4)445..501
Exon (5)502..546
Exon (6)547..624
Exon (7)625..693
Exon (8)694..778
Exon (9)779..900
Exon (10)901..991
Exon (11)992..1122
Exon (12)1123..1152
Exon (13)1153..1275
Exon (14)1276..1415
Exon (15)1416..1460
Exon (16)1461..1531
Exon (17)1532..1631
Exon (18)1632..1719
Exon (19)1720..1794
Exon (20)1795..1890
Exon (21)1891..1989
Exon (22)1990..2121
Exon (23)2122..2203
Exon (24)2204..2337
Exon (25)2338..3065
Translation

Target ORF information:

RefSeq Version NM_001190723.2
Organism Homo sapiens(Human)
Definition Homo sapiens leucine rich repeat and sterile alpha motif containing 1 (LRSAM1), transcript variant 4, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
NM_001190723.2

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
1501
1561
1621
1681
1741
1801
1861
1921
1981
2041
ATGCCGCTCT TCTTCCGGAA GCGGAAACCC AGTGAGGAGG CTCGGAAACG CCTGGAGTAC 
CAGATGTGTT TGGCAAAAGA AGCTGGGGCA GATGACATTC TCGACATCTC TAAATGTGAG
CTCTCAGAGA TTCCATTTGG AGCTTTTGCA ACATGCAAAG TTCTGCAGAA GAAGGTGCTG
ATCGTCCACA CGAATCACCT CACTTCCCTG CTTCCCAAAT CCTGCAGCCT CCTGAGTCTG
GCAACCATCA AGGTTCTAGA TCTCCACGAT AATCAGCTGA CAGCCCTTCC TGACGATCTG
GGGCAGCTGA CTGCCCTCCA GGTCTTAAAC GTGGAAAGGA ATCAACTGAT GCAGCTCCCA
CGTTCCATTG GGAACCTGAC CCAGCTCCAG ACTCTCAATG TTAAAGACAA CAAGCTGAAG
GAGCTTCCAG ACACCGTGGG GGAGCTTCGA AGCCTGCGTA CCCTCAACAT CAGTGGAAAC
GAGATCCAGA GATTGCCGCA GATGCTGGCT CACGTTCGAA CCCTGGAGAT GCTGAGCCTT
GACGCCTCGG CCATGGTCTA CCCGCCGCGG GAGGTGTGTG GTGCCGGCAC TGCGGCCATC
TTGCAGTTCC TCTGCAAAGA GTCAGGGCTG GAATACTACC CCCCTTCTCA GTACTTGCTG
CCAATTCTGG AGCAAGATGG AATCGAGAAC TCTCGGGACA GCCCTGATGG GCCCACGGAC
AGATTCTCAA GGGAGGAGTT AGAGTGGCAG AACAGGTTCT CAGACTATGA GAAGAGGAAG
GAACAGAAGA TGCTGGAGAA ACTCGAGTTT GAACGGCGCC TGGAACTGGG GCAGCGGGAG
CACACCCAGC TCCTTCAGCA GAGCAGCAGC CAGAAGGATG AGATCCTTCA GACGGTCAAG
GAGGAGCAGT CCCGGCTGGA GCAGGGCCTG AGTGAGCACC AGCGCCACCT CAACGCAGAG
CGGCAGCGGC TGCAGGAGCA GCTGAAGCAG ACGGAACAGA ACATTTCCAG CCGGATCCAG
AAGCTGCTGC AGGACAATCA GAGACAAAAG AAAAGCTCCG AGATTTTGAA ATCGCTGGAA
AATGAAAGAA TAAGAATGGA ACAGTTGATG TCCATAACCC AGGAGGAGAC TGAGAGCCTG
CGGCGACGTG ACGTTGCCTC CGCCATGCAG CAGATGCTGA CTGAGAGCTG TAAGAACCGG
CTCATCCAGA TGGCCTACGA ATCTCAGAGG CAGAACTTGG TCCAGCAGGC CTGTTCCAGC
ATGGCCGAAA TGGATGAACG ATTCCAGCAG ATTCTGTCGT GGCAGCAAAT GGATCAGAAC
AAAGCCATCA GCCAGATCCT GCAGGAGAGC GCGATGCAGA AGGCTGCGTT CGAGGCACTC
CAGGTGAAGA AAGACCTGAT GCATCGGCAG ATCAGGAGCC AGGAGATGAT CTCGGAGCAG
CGCTGGGCCC TCAGCTCCCT GCTCCAGCAG CTGCTCAAAG AGAAGCAGCA GCGAGAGGAA
GAGCTCCGGG AAATCCTGAC GGAGTTAGAA GCCAAAAGTG AAACCAGGCA GGAAAATTAC
TGGCTGATTC AGTATCAACG GCTTTTGAAC CAGAAGCCCT TGTCCTTGAA GCTGCAAGAA
GAGGGGATGG AGCGCCAGCT GGTGGCCCTC CTGGAGGAGC TGTCGGCTGA GCACTACCTG
CCCATCTTTG CGCACCACCG CCTCTCACTG GACCTGCTGA GCCAAATGAG CCCAGGGGAC
CTGGCCAAGG TGGGCGTCTC AGAAGCTGGC CTGCAGCACG AGATCCTCCG GAGAGTCCAG
GAACTGCTGG ATGCAGCCAG GATCCAGCCA GAGCTGAAAC CACCAATGGG TGAGGTCGTC
ACCCCTACGG CCCCCCAGGA GCCTCCTGAG TCTGTGAGGC CATCCGCTCC CCCTGCAGAG
CTGGAGGTGC AGGCCTCAGA GTGTGTCGTG TGCCTGGAAC GGGAGGCCCA GATGATCTTC
CTCAACTGTG GCCACGTCTG CTGCTGCCAG CAGTGCTGCC AGCCACTGCG CACCTGCCCG
CTGTGCCGCC AGGACATCGC CCAGCGCCTC CGCATCTACC ACAGCAGCTG A

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OHu26634
Clone ID Related Accession (Same CDS sequence) NM_001005373.3 , NM_138361.5 , XM_017015283.1 , NM_001005374.3
Accession Version XM_017015283.1 Latest version! Documents for ORF clone product in dufault vector
Sequence Information ORF Nucleotide Sequence (Length: 2172bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ® Seamless cloning technology
Insert Structure linear
Update Date 2016-06-06
Organism Homo sapiens(Human)
Product E3 ubiquitin-protein ligase LRSAM1 isoform X1
Comment MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000009.12) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Homo sapiens Annotation Release 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
1501
1561
1621
1681
1741
1801
1861
1921
1981
2041
2101
2161
ATGCCGCTCT TCTTCCGGAA GCGGAAACCC AGTGAGGAGG CTCGGAAACG CCTGGAGTAC 
CAGATGTGTT TGGCAAAAGA AGCTGGGGCA GATGACATTC TCGACATCTC TAAATGTGAG
CTCTCAGAGA TTCCATTTGG AGCTTTTGCA ACATGCAAAG TTCTGCAGAA GAAGGTGCTG
ATCGTCCACA CGAATCACCT CACTTCCCTG CTTCCCAAAT CCTGCAGCCT CCTGAGTCTG
GCAACCATCA AGGTTCTAGA TCTCCACGAT AATCAGCTGA CAGCCCTTCC TGACGATCTG
GGGCAGCTGA CTGCCCTCCA GGTCTTAAAC GTGGAAAGGA ATCAACTGAT GCAGCTCCCA
CGTTCCATTG GGAACCTGAC CCAGCTCCAG ACTCTCAATG TTAAAGACAA CAAGCTGAAG
GAGCTTCCAG ACACCGTGGG GGAGCTTCGA AGCCTGCGTA CCCTCAACAT CAGTGGAAAC
GAGATCCAGA GATTGCCGCA GATGCTGGCT CACGTTCGAA CCCTGGAGAT GCTGAGCCTT
GACGCCTCGG CCATGGTCTA CCCGCCGCGG GAGGTGTGTG GTGCCGGCAC TGCGGCCATC
TTGCAGTTCC TCTGCAAAGA GTCAGGGCTG GAATACTACC CCCCTTCTCA GTACTTGCTG
CCAATTCTGG AGCAAGATGG AATCGAGAAC TCTCGGGACA GCCCTGATGG GCCCACGGAC
AGATTCTCAA GGGAGGAGTT AGAGTGGCAG AACAGGTTCT CAGACTATGA GAAGAGGAAG
GAACAGAAGA TGCTGGAGAA ACTCGAGTTT GAACGGCGCC TGGAACTGGG GCAGCGGGAG
CACACCCAGC TCCTTCAGCA GAGCAGCAGC CAGAAGGATG AGATCCTTCA GACGGTCAAG
GAGGAGCAGT CCCGGCTGGA GCAGGGCCTG AGTGAGCACC AGCGCCACCT CAACGCAGAG
CGGCAGCGGC TGCAGGAGCA GCTGAAGCAG ACGGAACAGA ACATTTCCAG CCGGATCCAG
AAGCTGCTGC AGGACAATCA GAGACAAAAG AAAAGCTCCG AGATTTTGAA ATCGCTGGAA
AATGAAAGAA TAAGAATGGA ACAGTTGATG TCCATAACCC AGGAGGAGAC TGAGAGCCTG
CGGCGACGTG ACGTTGCCTC CGCCATGCAG CAGATGCTGA CTGAGAGCTG TAAGAACCGG
CTCATCCAGA TGGCCTACGA ATCTCAGAGG CAGAACTTGG TCCAGCAGGC CTGTTCCAGC
ATGGCCGAAA TGGATGAACG ATTCCAGCAG ATTCTGTCGT GGCAGCAAAT GGATCAGAAC
AAAGCCATCA GCCAGATCCT GCAGGAGAGC GCGATGCAGA AGGCTGCGTT CGAGGCACTC
CAGGTGAAGA AAGACCTGAT GCATCGGCAG ATCAGGAGCC AGATTAAGTT AATAGAAACT
GAGTTATTGC AGCTGACACA GCTGGAGTTA AAGAGGAAGT CCCTGGACAC AGAGTCACTC
CAGGAGATGA TCTCGGAGCA GCGCTGGGCC CTCAGCTCCC TGCTCCAGCA GCTGCTCAAA
GAGAAGCAGC AGCGAGAGGA AGAGCTCCGG GAAATCCTGA CGGAGTTAGA AGCCAAAAGT
GAAACCAGGC AGGAAAATTA CTGGCTGATT CAGTATCAAC GGCTTTTGAA CCAGAAGCCC
TTGTCCTTGA AGCTGCAAGA AGAGGGGATG GAGCGCCAGC TGGTGGCCCT CCTGGAGGAG
CTGTCGGCTG AGCACTACCT GCCCATCTTT GCGCACCACC GCCTCTCACT GGACCTGCTG
AGCCAAATGA GCCCAGGGGA CCTGGCCAAG GTGGGCGTCT CAGAAGCTGG CCTGCAGCAC
GAGATCCTCC GGAGAGTCCA GGAACTGCTG GATGCAGCCA GGATCCAGCC AGAGCTGAAA
CCACCAATGG GTGAGGTCGT CACCCCTACG GCCCCCCAGG AGCCTCCTGA GTCTGTGAGG
CCATCCGCTC CCCCTGCAGA GCTGGAGGTG CAGGCCTCAG AGTGTGTCGT GTGCCTGGAA
CGGGAGGCCC AGATGATCTT CCTCAACTGT GGCCACGTCT GCTGCTGCCA GCAGTGCTGC
CAGCCACTGC GCACCTGCCC GCTGTGCCGC CAGGACATCG CCCAGCGCCT CCGCATCTAC
CACAGCAGCT GA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq XP_016870772.1
CDS1372..3543
Misc Feature(1)1468..1533
Misc Feature(2)1534..1617
Misc Feature(3)1543..1719
Misc Feature(4)<1570..1857
Misc Feature(5)1618..1686
Misc Feature(6)1687..1755
Misc Feature(7)1750..1914
Misc Feature(8)1750..1869
Misc Feature(9)1756..1824
Misc Feature(10)<2293..2619
Misc Feature(11)3070..3264
Misc Feature(12)3082..3264
Misc Feature(13)3391..3519
Translation

Target ORF information:

RefSeq Version XM_017015283.1
Organism Homo sapiens(Human)
Definition Homo sapiens leucine rich repeat and sterile alpha motif containing 1 (LRSAM1), transcript variant X1, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
XM_017015283.1

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
1501
1561
1621
1681
1741
1801
1861
1921
1981
2041
2101
2161
ATGCCGCTCT TCTTCCGGAA GCGGAAACCC AGTGAGGAGG CTCGGAAACG CCTGGAGTAC 
CAGATGTGTT TGGCAAAAGA AGCTGGGGCA GATGACATTC TCGACATCTC TAAATGTGAG
CTCTCAGAGA TTCCATTTGG AGCTTTTGCA ACATGCAAAG TTCTGCAGAA GAAGGTGCTG
ATCGTCCACA CGAATCACCT CACTTCCCTG CTTCCCAAAT CCTGCAGCCT CCTGAGTCTG
GCAACCATCA AGGTTCTAGA TCTCCACGAT AATCAGCTGA CAGCCCTTCC TGACGATCTG
GGGCAGCTGA CTGCCCTCCA GGTCTTAAAC GTGGAAAGGA ATCAACTGAT GCAGCTCCCA
CGTTCCATTG GGAACCTGAC CCAGCTCCAG ACTCTCAATG TTAAAGACAA CAAGCTGAAG
GAGCTTCCAG ACACCGTGGG GGAGCTTCGA AGCCTGCGTA CCCTCAACAT CAGTGGAAAC
GAGATCCAGA GATTGCCGCA GATGCTGGCT CACGTTCGAA CCCTGGAGAT GCTGAGCCTT
GACGCCTCGG CCATGGTCTA CCCGCCGCGG GAGGTGTGTG GTGCCGGCAC TGCGGCCATC
TTGCAGTTCC TCTGCAAAGA GTCAGGGCTG GAATACTACC CCCCTTCTCA GTACTTGCTG
CCAATTCTGG AGCAAGATGG AATCGAGAAC TCTCGGGACA GCCCTGATGG GCCCACGGAC
AGATTCTCAA GGGAGGAGTT AGAGTGGCAG AACAGGTTCT CAGACTATGA GAAGAGGAAG
GAACAGAAGA TGCTGGAGAA ACTCGAGTTT GAACGGCGCC TGGAACTGGG GCAGCGGGAG
CACACCCAGC TCCTTCAGCA GAGCAGCAGC CAGAAGGATG AGATCCTTCA GACGGTCAAG
GAGGAGCAGT CCCGGCTGGA GCAGGGCCTG AGTGAGCACC AGCGCCACCT CAACGCAGAG
CGGCAGCGGC TGCAGGAGCA GCTGAAGCAG ACGGAACAGA ACATTTCCAG CCGGATCCAG
AAGCTGCTGC AGGACAATCA GAGACAAAAG AAAAGCTCCG AGATTTTGAA ATCGCTGGAA
AATGAAAGAA TAAGAATGGA ACAGTTGATG TCCATAACCC AGGAGGAGAC TGAGAGCCTG
CGGCGACGTG ACGTTGCCTC CGCCATGCAG CAGATGCTGA CTGAGAGCTG TAAGAACCGG
CTCATCCAGA TGGCCTACGA ATCTCAGAGG CAGAACTTGG TCCAGCAGGC CTGTTCCAGC
ATGGCCGAAA TGGATGAACG ATTCCAGCAG ATTCTGTCGT GGCAGCAAAT GGATCAGAAC
AAAGCCATCA GCCAGATCCT GCAGGAGAGC GCGATGCAGA AGGCTGCGTT CGAGGCACTC
CAGGTGAAGA AAGACCTGAT GCATCGGCAG ATCAGGAGCC AGATTAAGTT AATAGAAACT
GAGTTATTGC AGCTGACACA GCTGGAGTTA AAGAGGAAGT CCCTGGACAC AGAGTCACTC
CAGGAGATGA TCTCGGAGCA GCGCTGGGCC CTCAGCTCCC TGCTCCAGCA GCTGCTCAAA
GAGAAGCAGC AGCGAGAGGA AGAGCTCCGG GAAATCCTGA CGGAGTTAGA AGCCAAAAGT
GAAACCAGGC AGGAAAATTA CTGGCTGATT CAGTATCAAC GGCTTTTGAA CCAGAAGCCC
TTGTCCTTGA AGCTGCAAGA AGAGGGGATG GAGCGCCAGC TGGTGGCCCT CCTGGAGGAG
CTGTCGGCTG AGCACTACCT GCCCATCTTT GCGCACCACC GCCTCTCACT GGACCTGCTG
AGCCAAATGA GCCCAGGGGA CCTGGCCAAG GTGGGCGTCT CAGAAGCTGG CCTGCAGCAC
GAGATCCTCC GGAGAGTCCA GGAACTGCTG GATGCAGCCA GGATCCAGCC AGAGCTGAAA
CCACCAATGG GTGAGGTCGT CACCCCTACG GCCCCCCAGG AGCCTCCTGA GTCTGTGAGG
CCATCCGCTC CCCCTGCAGA GCTGGAGGTG CAGGCCTCAG AGTGTGTCGT GTGCCTGGAA
CGGGAGGCCC AGATGATCTT CCTCAACTGT GGCCACGTCT GCTGCTGCCA GCAGTGCTGC
CAGCCACTGC GCACCTGCCC GCTGTGCCGC CAGGACATCG CCCAGCGCCT CCGCATCTAC
CACAGCAGCT GA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OHu43578
Clone ID Related Accession (Same CDS sequence) XM_006717316.3
Accession Version XM_006717316.3 Latest version! Documents for ORF clone product in dufault vector
Sequence Information ORF Nucleotide Sequence (Length: 2073bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ® Seamless cloning technology
Insert Structure linear
Update Date 2016-06-06
Organism Homo sapiens(Human)
Product E3 ubiquitin-protein ligase LRSAM1 isoform X2
Comment MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000009.12) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 6, 2016 this sequence version replaced XM_006717316.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Homo sapiens Annotation Release 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
1501
1561
1621
1681
1741
1801
1861
1921
1981
2041
ATGCCGCTCT TCTTCCGGAA GCGGAAACCC AGTGAGGAGG CTCGGAAACG CCTGGAGTAC 
CAGATGTGTT TGGCAAAAGA AGCTGGGGCA GATGACATTC TCGACATCTC TAAATGTGAG
CTCTCAGAGA TTCCATTTGG AGCTTTTGCA ACATGCAAAG TTCTGCAGAA GAAGGTGCTG
ATCGTCCACA CGAATCACCT CACTTCCCTG CTTCCCAAAT CCTGCAGCCT CCTGAGTCTG
GCAACCATCA AGGTTCTAGA TCTCCACGAT AATCAGCTGA CAGCCCTTCC TGACGATCTG
GGGCAGCTGA CTGCCCTCCA GGTCTTAAAC GTGGAAAGGA ATCAACTGAT GCAGCTCCCA
CGTTCCATTG GGAACCTGAC CCAGCTCCAG ACTCTCAATG TTAAAGACAA CAAGCTGAAG
GAGCTTCCAG ACACCGTGGG GGAGCTTCGA AGCCTGCGTA CCCTCAACAT CAGTGGAAAC
GAGATCCAGA GATTGCCGCA GATGCTGGCT CACGTTCGAA CCCTGGAGAT GCTGAGCCTT
GACGCCTCGG CCATGGTCTA CCCGCCGCGG GAGGTGTGTG GTGCCGGCAC TGCGGCCATC
TTGCAGTTCC TCTGCAAAGA GTCAGGGCTG GAATACTACC CCCCTTCTCA GTACTTGCTG
CCAATTCTGG AGCAAGATGG AATCGAGAAC TCTCGGGACA GCCCTGATGG GCCCACGGAC
AGATTCTCAA GGGAGGAGTT AGAGTGGCAG AACAGGTTCT CAGACTATGA GAAGAGGAAG
GAACAGAAGA TGCTGGAGAA ACTCGAGTTT GAACGGCGCC TGGAACTGGG GCAGCGGGAG
CACACCCAGC TCCTTCAGCA GAGCAGCAGC CAGAAGGATG AGATCCTTCA GACGGTCAAG
GAGGAGCAGT CCCGGCTGGA GCAGGGCCTG AGTGAGCACC AGCGCCACCT CAACGCAGAG
CGGCAGCGGC TGCAGGAGCA GCTGAAGCAG ACGGAACAGA ACATTTCCAG CCGGATCCAG
AAGCTGCTGC AGGACAATCA GAGACAAAAG AAAAGCTCCG AGATTTTGAA ATCGCTGGAA
AATGAAAGAA TAAGAATGGA ACAGTTGATG TCCATAACCC AGGAGGAGAC TGAGAGCCTG
CGGCGACGTG ACGTTGCCTC CGCCATGCAG CAGATGCTGA CTGAGAGCTG TAAGAACCGG
CTCATCCAGA TGGCCTACGA ATCTCAGAGG CAGAACTTGG TCCAGCAGGC CTGTTCCAGC
ATGGCCGAAA TGGATGAACG ATTCCAGCAG ATTCTGTCGT GGCAGCAAAT GGATCAGAAC
AAAGCCATCA GCCAGATCCT GCAGGAGAGC GCGATGCAGA AGGCTGCGTT CGAGGCACTC
CAGGTGAAGA AAGACCTGAT GCATCGGCAG ATCAGGAGCC AGATTAAGTT AATAGAAACT
GAGTTATTGC AGCTGACACA GCTGGAGTTA AAGAGGAAGT CCCTGGACAC AGAGTCACTC
CAGGAGATGA TCTCGGAGCA GCGCTGGGCC CTCAGCTCCC TGCTCCAGCA GCTGCTCAAA
GAGAAGCAGC AGCGAGAGGA AGAGCTCCGG GAAATCCTGG AAGAGGGGAT GGAGCGCCAG
CTGGTGGCCC TCCTGGAGGA GCTGTCGGCT GAGCACTACC TGCCCATCTT TGCGCACCAC
CGCCTCTCAC TGGACCTGCT GAGCCAAATG AGCCCAGGGG ACCTGGCCAA GGTGGGCGTC
TCAGAAGCTG GCCTGCAGCA CGAGATCCTC CGGAGAGTCC AGGAACTGCT GGATGCAGCC
AGGATCCAGC CAGAGCTGAA ACCACCAATG GGTGAGGTCG TCACCCCTAC GGCCCCCCAG
GAGCCTCCTG AGTCTGTGAG GCCATCCGCT CCCCCTGCAG AGCTGGAGGT GCAGGCCTCA
GAGTGTGTCG TGTGCCTGGA ACGGGAGGCC CAGATGATCT TCCTCAACTG TGGCCACGTC
TGCTGCTGCC AGCAGTGCTG CCAGCCACTG CGCACCTGCC CGCTGTGCCG CCAGGACATC
GCCCAGCGCC TCCGCATCTA CCACAGCAGC TGA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq XP_006717379.1
CDS373..2445
Misc Feature(1)469..534
Misc Feature(2)535..618
Misc Feature(3)544..720
Misc Feature(4)<571..858
Misc Feature(5)619..687
Misc Feature(6)688..756
Misc Feature(7)751..915
Misc Feature(8)751..870
Misc Feature(9)757..825
Misc Feature(10)1141..1449
Misc Feature(11)<1294..1620
Misc Feature(12)1978..2166
Misc Feature(13)1984..2166
Misc Feature(14)2293..2421
Translation

Target ORF information:

RefSeq Version XM_006717316.3
Organism Homo sapiens(Human)
Definition Homo sapiens leucine rich repeat and sterile alpha motif containing 1 (LRSAM1), transcript variant X2, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
XM_006717316.3

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
1501
1561
1621
1681
1741
1801
1861
1921
1981
2041
ATGCCGCTCT TCTTCCGGAA GCGGAAACCC AGTGAGGAGG CTCGGAAACG CCTGGAGTAC 
CAGATGTGTT TGGCAAAAGA AGCTGGGGCA GATGACATTC TCGACATCTC TAAATGTGAG
CTCTCAGAGA TTCCATTTGG AGCTTTTGCA ACATGCAAAG TTCTGCAGAA GAAGGTGCTG
ATCGTCCACA CGAATCACCT CACTTCCCTG CTTCCCAAAT CCTGCAGCCT CCTGAGTCTG
GCAACCATCA AGGTTCTAGA TCTCCACGAT AATCAGCTGA CAGCCCTTCC TGACGATCTG
GGGCAGCTGA CTGCCCTCCA GGTCTTAAAC GTGGAAAGGA ATCAACTGAT GCAGCTCCCA
CGTTCCATTG GGAACCTGAC CCAGCTCCAG ACTCTCAATG TTAAAGACAA CAAGCTGAAG
GAGCTTCCAG ACACCGTGGG GGAGCTTCGA AGCCTGCGTA CCCTCAACAT CAGTGGAAAC
GAGATCCAGA GATTGCCGCA GATGCTGGCT CACGTTCGAA CCCTGGAGAT GCTGAGCCTT
GACGCCTCGG CCATGGTCTA CCCGCCGCGG GAGGTGTGTG GTGCCGGCAC TGCGGCCATC
TTGCAGTTCC TCTGCAAAGA GTCAGGGCTG GAATACTACC CCCCTTCTCA GTACTTGCTG
CCAATTCTGG AGCAAGATGG AATCGAGAAC TCTCGGGACA GCCCTGATGG GCCCACGGAC
AGATTCTCAA GGGAGGAGTT AGAGTGGCAG AACAGGTTCT CAGACTATGA GAAGAGGAAG
GAACAGAAGA TGCTGGAGAA ACTCGAGTTT GAACGGCGCC TGGAACTGGG GCAGCGGGAG
CACACCCAGC TCCTTCAGCA GAGCAGCAGC CAGAAGGATG AGATCCTTCA GACGGTCAAG
GAGGAGCAGT CCCGGCTGGA GCAGGGCCTG AGTGAGCACC AGCGCCACCT CAACGCAGAG
CGGCAGCGGC TGCAGGAGCA GCTGAAGCAG ACGGAACAGA ACATTTCCAG CCGGATCCAG
AAGCTGCTGC AGGACAATCA GAGACAAAAG AAAAGCTCCG AGATTTTGAA ATCGCTGGAA
AATGAAAGAA TAAGAATGGA ACAGTTGATG TCCATAACCC AGGAGGAGAC TGAGAGCCTG
CGGCGACGTG ACGTTGCCTC CGCCATGCAG CAGATGCTGA CTGAGAGCTG TAAGAACCGG
CTCATCCAGA TGGCCTACGA ATCTCAGAGG CAGAACTTGG TCCAGCAGGC CTGTTCCAGC
ATGGCCGAAA TGGATGAACG ATTCCAGCAG ATTCTGTCGT GGCAGCAAAT GGATCAGAAC
AAAGCCATCA GCCAGATCCT GCAGGAGAGC GCGATGCAGA AGGCTGCGTT CGAGGCACTC
CAGGTGAAGA AAGACCTGAT GCATCGGCAG ATCAGGAGCC AGATTAAGTT AATAGAAACT
GAGTTATTGC AGCTGACACA GCTGGAGTTA AAGAGGAAGT CCCTGGACAC AGAGTCACTC
CAGGAGATGA TCTCGGAGCA GCGCTGGGCC CTCAGCTCCC TGCTCCAGCA GCTGCTCAAA
GAGAAGCAGC AGCGAGAGGA AGAGCTCCGG GAAATCCTGG AAGAGGGGAT GGAGCGCCAG
CTGGTGGCCC TCCTGGAGGA GCTGTCGGCT GAGCACTACC TGCCCATCTT TGCGCACCAC
CGCCTCTCAC TGGACCTGCT GAGCCAAATG AGCCCAGGGG ACCTGGCCAA GGTGGGCGTC
TCAGAAGCTG GCCTGCAGCA CGAGATCCTC CGGAGAGTCC AGGAACTGCT GGATGCAGCC
AGGATCCAGC CAGAGCTGAA ACCACCAATG GGTGAGGTCG TCACCCCTAC GGCCCCCCAG
GAGCCTCCTG AGTCTGTGAG GCCATCCGCT CCCCCTGCAG AGCTGGAGGT GCAGGCCTCA
GAGTGTGTCG TGTGCCTGGA ACGGGAGGCC CAGATGATCT TCCTCAACTG TGGCCACGTC
TGCTGCTGCC AGCAGTGCTG CCAGCCACTG CGCACCTGCC CGCTGTGCCG CCAGGACATC
GCCCAGCGCC TCCGCATCTA CCACAGCAGC TGA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

book

The MEKK1 PHD ubiquitinates TAB1 to activate MAPKs in response to cytokines.
The EMBO journal33(21)2581-96(2014 Nov)
Charlaftis N,Suddason T,Wu X,Anwar S,Karin M,Gallagher E


book

A novel mutation in LRSAM1 causes axonal Charcot-Marie-Tooth disease with dominant inheritance.
BMC neurology14118(2014 Jun)
Engeholm M,Sekler J,Schöndorf DC,Arora V,Schittenhelm J,Biskup S,Schell C,Gasser T


book

PHF23 (plant homeodomain finger protein 23) negatively regulates cell autophagy by promoting ubiquitination and degradation of E3 ligase LRSAM1.
Autophagy10(12)2158-70(2014)
Wang Z,Hu J,Li G,Qu L,He Q,Lou Y,Song Q,Ma D,Chen Y


book

The LRR and RING domain protein LRSAM1 is an E3 ligase crucial for ubiquitin-dependent autophagy of intracellular Salmonella Typhimurium.
Cell host & microbe12(6)778-90(2012 Dec)
Huett A,Heath RJ,Begun J,Sassi SO,Baxt LA,Vyas JM,Goldberg MB,Xavier RJ


book

Human leucine-rich repeat proteins: a genome-wide bioinformatic categorization and functional analysis in innate immunity.
Proceedings of the National Academy of Sciences of the United States of America108 Suppl 14631-8(2011 Mar)
Ng AC,Eisenberg JM,Heath RJ,Huett A,Robinson CM,Nau GJ,Xavier RJ


 
*
*
*
*