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GRHPR cDNA ORF clone, Homo sapiens (human)

Gene Symbol GRHPR
Entrez Gene ID 9380
Full Name glyoxylate reductase/hydroxypyruvate reductase
Synonyms GLXR, GLYD, PH2
General protein information
Preferred Names
glyoxylate reductase/hydroxypyruvate reductase
Names
glyoxylate reductase/hydroxypyruvate reductase
glycerate-2-dehydrogenase
NP_036335.1
Gene Type protein-coding
Organism Homo sapiens (human)
Genome

9

9q12

Summary This gene encodes an enzyme with hydroxypyruvate reductase, glyoxylate reductase, and D-glycerate dehydrogenase enzymatic activities. The enzyme has widespread tissue expression and has a role in metabolism. Type II hyperoxaluria is caused by mutations in this gene. [provided by RefSeq, Jul 2008]. lac of sum
Disorder MIM:

604296

Disorder Html: Hyperoxaluria, primary, type II, 260000 (3)

mRNA and Protein(s)

mRNA Protein Name
XM_005251631 XP_005251688 glyoxylate reductase/hydroxypyruvate reductase isoform X1
XM_011518073 XP_011516375 glyoxylate reductase/hydroxypyruvate reductase isoform X2
NM_012203 NP_036335 glyoxylate reductase/hydroxypyruvate reductase



Homo sapiens (human) GRHPR NP_036335.1
Pan troglodytes (chimpanzee) GRHPR XP_520581.3
Macaca mulatta (Rhesus monkey) LOC718494 XP_002800095.1
Canis lupus familiaris (dog) GRHPR XP_005626882.1
Bos taurus (cattle) GRHPR NP_001178966.1
Mus musculus (house mouse) Grhpr NP_525028.1
Rattus norvegicus (Norway rat) Grhpr NP_001107226.1
Gallus gallus (chicken) GRHPR XP_424417.3
Danio rerio (zebrafish) grhpra NP_001018361.1
Drosophila melanogaster (fruit fly) CG1236 NP_649579.2
Arabidopsis thaliana (thale cress) AT1G79870 NP_178105.1
Xenopus (Silurana) tropicalis (western clawed frog) grhpr.2 NP_001007896.1
Xenopus (Silurana) tropicalis (western clawed frog) grhpr.1 NP_001072783.2


Related articles in PubMed

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following GRHPR gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the GRHPR cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID RefSeq Accession Definition **Vector *Turnaround time Price Select
OHu42881 XM_005251631 PREDICTED: Homo sapiens glyoxylate reductase/hydroxypyruvate reductase (GRHPR), transcript variant X2, mRNA. pcDNA3.1+/C-(K)DYK or customized vector 7-9 $139.30
$199.00
OHu62784 XM_011518073 PREDICTED: Homo sapiens glyoxylate reductase/hydroxypyruvate reductase (GRHPR), transcript variant X3, mRNA. pcDNA3.1+/C-(K)DYK or customized vector 7-9 $69.30
$99.00
OHu19343 NM_012203 Homo sapiens glyoxylate reductase/hydroxypyruvate reductase (GRHPR), mRNA. pcDNA3.1+/C-(K)DYK or customized vector 7-9 $69.30
$99.00
Next-day Shipping ORF Clones ( in default vector with tag)
1 Clone 30% OFF
2-4 Clone 40% OFF
5 or more Clone 50% OFF
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*Business Day

** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.


CloneID OHu42881
Clone ID Related Accession (Same CDS sequence) XM_005251631
Accession Version XM_005251631.1 Documents for ORF clone product in dufault vector
Sequence Information ORF Nucleotide Sequence (Length: 666bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ® Seamless cloning technology
Structure linear
Update Date 12-MAR-2015
Organism Homo sapiens (human)
Product glyoxylate reductase/hydroxypyruvate reductase isoform X1
Comment MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NT_008413.19) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Homo sapiens Annotation Release 107 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 6.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

1
61
121
181
241
301
361
421
481
541
601
661
ATGAGACCGG TGCGACTCAT GAAGGTGTTC GTCACCCGCA GGATACCCGC CGAGGGTAGG 
GTCGCGCTCG CCCGGGCGGC AGATGGTGGC TGGACCTCGT GGAAGCCCCT CTGGCTGTGT
GGCTATGGAC TCACGCAGAG CACTGTCGGC ATCATCGGGC TGGGGCGCAT AGGCCAGGCC
ATTGCTCGGC GTCTGAAACC ATTCGGTGTC CAGAGATTTC TGTACACAGG GCGCCAGCCC
AGGCCTGAGG AAGCAGCAGA ATTCCAGGCA GAGTTTGTGT CTACCCCTGA GCTGGCTGCC
CAATCTGATT TCATCGTCGT GGCCTGCTCC TTAACACCTG CAACCGAGGG ACTCTGCAAC
AAGGACTTCT TCCAGAAGAT GAAGGAAACA GCTGTGTTCA TCAACATCAG CAGGGGCGAC
GTCGTAAACC AGGACGACCT GTACCAGGCC TTGGCCAGTG GTAAGATTGC AGCTGCTGGA
CTGGATGTGA CGAGCCCAGA ACCACTGCCT ACAAACCACC CTCTCCTGAC CCTGAAGAAC
TGTGTGATTC TGCCCCACAT TGGCAGTGCC ACCCACAGAA CCCGCAACAC CATGTCCTTG
TTGGCAGCTA ACAACTTGCT GGCTGGCCTG AGAGGGGAGC CGATGCCTAG TGAACTCAAG
CTGTAG

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq XP_005251688.1
CDS56..721
Misc Feature(1)86..715(+)
Misc Feature(2)86..691(+)
Misc Feature(3)212..463(+)
Translation

Target ORF information:

RefSeq Version XM_005251631
Organism Homo sapiens (human)
Definition PREDICTED: Homo sapiens glyoxylate reductase/hydroxypyruvate reductase (GRHPR), transcript variant X2, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
XM_005251631

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
ATGAGACCGG TGCGACTCAT GAAGGTGTTC GTCACCCGCA GGATACCCGC CGAGGGTAGG 
GTCGCGCTCG CCCGGGCGGC AGATGGTGGC TGGACCTCGT GGAAGCCCCT CTGGCTGTGT
GGCTATGGAC TCACGCAGAG CACTGTCGGC ATCATCGGGC TGGGGCGCAT AGGCCAGGCC
ATTGCTCGGC GTCTGAAACC ATTCGGTGTC CAGAGATTTC TGTACACAGG GCGCCAGCCC
AGGCCTGAGG AAGCAGCAGA ATTCCAGGCA GAGTTTGTGT CTACCCCTGA GCTGGCTGCC
CAATCTGATT TCATCGTCGT GGCCTGCTCC TTAACACCTG CAACCGAGGG ACTCTGCAAC
AAGGACTTCT TCCAGAAGAT GAAGGAAACA GCTGTGTTCA TCAACATCAG CAGGGGCGAC
GTCGTAAACC AGGACGACCT GTACCAGGCC TTGGCCAGTG GTAAGATTGC AGCTGCTGGA
CTGGATGTGA CGAGCCCAGA ACCACTGCCT ACAAACCACC CTCTCCTGAC CCTGAAGAAC
TGTGTGATTC TGCCCCACAT TGGCAGTGCC ACCCACAGAA CCCGCAACAC CATGTCCTTG
TTGGCAGCTA ACAACTTGCT GGCTGGCCTG AGAGGGGAGC CGATGCCTAG TGAACTCAAG
CTGTAG

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OHu62784
Clone ID Related Accession (Same CDS sequence) XM_011518073
Accession Version XM_011518073.1 Documents for ORF clone product in dufault vector
Sequence Information ORF Nucleotide Sequence (Length: 585bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ® Seamless cloning technology
Structure linear
Update Date 12-MAR-2015
Organism Homo sapiens (human)
Product glyoxylate reductase/hydroxypyruvate reductase isoform X2
Comment MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NT_008413.19) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Homo sapiens Annotation Release 107 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 6.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

1
61
121
181
241
301
361
421
481
541
ATGAAGACTA CAAATGTGTT GGGGCCGTTA GGAGTGGTTA CCGTGAGAGA GCCCATTCCC 
CCGACACCTA CTCCGGCTTG CGTTCTGGAA GGCCAGGCCA TTGCTCGGCG TCTGAAACCA
TTCGGTGTCC AGAGATTTCT GTACACAGGG CGCCAGCCCA GGCCTGAGGA AGCAGCAGAA
TTCCAGGCAG AGTTTGTGTC TACCCCTGAG CTGGCTGCCC AATCTGATTT CATCGTCGTG
GCCTGCTCCT TAACACCTGC AACCGAGGGA CTCTGCAACA AGGACTTCTT CCAGAAGATG
AAGGAAACAG CTGTGTTCAT CAACATCAGC AGGGGCGACG TCGTAAACCA GGACGACCTG
TACCAGGCCT TGGCCAGTGG TAAGATTGCA GCTGCTGGAC TGGATGTGAC GAGCCCAGAA
CCACTGCCTA CAAACCACCC TCTCCTGACC CTGAAGAACT GTGTGATTCT GCCCCACATT
GGCAGTGCCA CCCACAGAAC CCGCAACACC ATGTCCTTGT TGGCAGCTAA CAACTTGCTG
GCTGGCCTGA GAGGGGAGCC GATGCCTAGT GAACTCAAGC TGTAG

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq XP_011516375.1
CDS794..1378
Misc Feature(1)884..1372(+)
Misc Feature(2)884..1348(+)
Misc Feature(3)938..1120(+)
Translation

Target ORF information:

RefSeq Version XM_011518073
Organism Homo sapiens (human)
Definition PREDICTED: Homo sapiens glyoxylate reductase/hydroxypyruvate reductase (GRHPR), transcript variant X3, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
XM_011518073

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
ATGAAGACTA CAAATGTGTT GGGGCCGTTA GGAGTGGTTA CCGTGAGAGA GCCCATTCCC 
CCGACACCTA CTCCGGCTTG CGTTCTGGAA GGCCAGGCCA TTGCTCGGCG TCTGAAACCA
TTCGGTGTCC AGAGATTTCT GTACACAGGG CGCCAGCCCA GGCCTGAGGA AGCAGCAGAA
TTCCAGGCAG AGTTTGTGTC TACCCCTGAG CTGGCTGCCC AATCTGATTT CATCGTCGTG
GCCTGCTCCT TAACACCTGC AACCGAGGGA CTCTGCAACA AGGACTTCTT CCAGAAGATG
AAGGAAACAG CTGTGTTCAT CAACATCAGC AGGGGCGACG TCGTAAACCA GGACGACCTG
TACCAGGCCT TGGCCAGTGG TAAGATTGCA GCTGCTGGAC TGGATGTGAC GAGCCCAGAA
CCACTGCCTA CAAACCACCC TCTCCTGACC CTGAAGAACT GTGTGATTCT GCCCCACATT
GGCAGTGCCA CCCACAGAAC CCGCAACACC ATGTCCTTGT TGGCAGCTAA CAACTTGCTG
GCTGGCCTGA GAGGGGAGCC GATGCCTAGT GAACTCAAGC TGTAG

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OHu19343
Clone ID Related Accession (Same CDS sequence) NM_012203
Accession Version NM_012203.1 Documents for ORF clone product in dufault vector
Sequence Information ORF Nucleotide Sequence (Length: 987bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ® Seamless cloning technology
Structure linear
Update Date 15-MAR-2015
Organism Homo sapiens (human)
Product glyoxylate reductase/hydroxypyruvate reductase
Comment REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AF134895.1. This sequence is a reference standard in the RefSeqGene project. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AF134895.1, BC003131.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
ATGAGACCGG TGCGACTCAT GAAGGTGTTC GTCACCCGCA GGATACCCGC CGAGGGTAGG 
GTCGCGCTCG CCCGGGCGGC AGACTGTGAG GTGGAGCAGT GGGACTCGGA TGAGCCCATC
CCTGCCAAGG AGCTAGAGCG AGGTGTGGCG GGGGCCCACG GCCTGCTCTG CCTCCTCTCC
GACCACGTGG ACAAGAGGAT CCTGGATGCT GCAGGGGCCA ATCTCAAAGT CATCAGCACC
ATGTCTGTGG GCATCGACCA CTTGGCTTTG GATGAAATCA AGAAGCGTGG GATCCGAGTT
GGCTACACCC CAGATGTCCT GACAGATACC ACCGCCGAAC TCGCAGTCTC CCTGCTACTT
ACCACCTGCC GCCGGTTGCC GGAGGCCATC GAGGAAGTGA AGAATGGTGG CTGGACCTCG
TGGAAGCCCC TCTGGCTGTG TGGCTATGGA CTCACGCAGA GCACTGTCGG CATCATCGGG
CTGGGGCGCA TAGGCCAGGC CATTGCTCGG CGTCTGAAAC CATTCGGTGT CCAGAGATTT
CTGTACACAG GGCGCCAGCC CAGGCCTGAG GAAGCAGCAG AATTCCAGGC AGAGTTTGTG
TCTACCCCTG AGCTGGCTGC CCAATCTGAT TTCATCGTCG TGGCCTGCTC CTTAACACCT
GCAACCGAGG GACTCTGCAA CAAGGACTTC TTCCAGAAGA TGAAGGAAAC AGCTGTGTTC
ATCAACATCA GCAGGGGCGA CGTCGTAAAC CAGGACGACC TGTACCAGGC CTTGGCCAGT
GGTAAGATTG CAGCTGCTGG ACTGGATGTG ACGAGCCCAG AACCACTGCC TACAAACCAC
CCTCTCCTGA CCCTGAAGAA CTGTGTGATT CTGCCCCACA TTGGCAGTGC CACCCACAGA
ACCCGCAACA CCATGTCCTT GTTGGCAGCT AACAACTTGC TGGCTGGCCT GAGAGGGGAG
CCGATGCCTA GTGAACTCAA GCTGTAG

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq NP_036335.1
CDS42..1028
Misc Feature(1)60..1022(+)
Misc Feature(2)60..998(+)
Misc Feature(3)78..947(+)
Misc Feature(4)216..929(+)
Misc Feature(5)288..929(+)
Misc Feature(6)288..293(+)
Misc Feature(7)774..920(+)
Misc Feature(8)861..863(+)
Misc Feature(9)918..929(+)
Exon (1)1..124
Gene:GRHPR
Gene Synonym:
Exon (2)125..255
Gene:GRHPR
Gene Synonym:
Exon (3)256..328
Gene:GRHPR
Gene Synonym:
Exon (4)329..445
Gene:GRHPR
Gene Synonym:
Exon (5)446..534
Gene:GRHPR
Gene Synonym:
Exon (6)535..639
Gene:GRHPR
Gene Synonym:
Exon (7)640..775
Gene:GRHPR
Gene Synonym:
Exon (8)776..906
Gene:GRHPR
Gene Synonym:
Exon (9)907..1235
Gene:GRHPR
Gene Synonym:
Translation

Target ORF information:

RefSeq Version NM_012203
Organism Homo sapiens (human)
Definition Homo sapiens glyoxylate reductase/hydroxypyruvate reductase (GRHPR), mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
NM_012203

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
ATGAGACCGG TGCGACTCAT GAAGGTGTTC GTCACCCGCA GGATACCCGC CGAGGGTAGG 
GTCGCGCTCG CCCGGGCGGC AGACTGTGAG GTGGAGCAGT GGGACTCGGA TGAGCCCATC
CCTGCCAAGG AGCTAGAGCG AGGTGTGGCG GGGGCCCACG GCCTGCTCTG CCTCCTCTCC
GACCACGTGG ACAAGAGGAT CCTGGATGCT GCAGGGGCCA ATCTCAAAGT CATCAGCACC
ATGTCTGTGG GCATCGACCA CTTGGCTTTG GATGAAATCA AGAAGCGTGG GATCCGAGTT
GGCTACACCC CAGATGTCCT GACAGATACC ACCGCCGAAC TCGCAGTCTC CCTGCTACTT
ACCACCTGCC GCCGGTTGCC GGAGGCCATC GAGGAAGTGA AGAATGGTGG CTGGACCTCG
TGGAAGCCCC TCTGGCTGTG TGGCTATGGA CTCACGCAGA GCACTGTCGG CATCATCGGG
CTGGGGCGCA TAGGCCAGGC CATTGCTCGG CGTCTGAAAC CATTCGGTGT CCAGAGATTT
CTGTACACAG GGCGCCAGCC CAGGCCTGAG GAAGCAGCAG AATTCCAGGC AGAGTTTGTG
TCTACCCCTG AGCTGGCTGC CCAATCTGAT TTCATCGTCG TGGCCTGCTC CTTAACACCT
GCAACCGAGG GACTCTGCAA CAAGGACTTC TTCCAGAAGA TGAAGGAAAC AGCTGTGTTC
ATCAACATCA GCAGGGGCGA CGTCGTAAAC CAGGACGACC TGTACCAGGC CTTGGCCAGT
GGTAAGATTG CAGCTGCTGG ACTGGATGTG ACGAGCCCAG AACCACTGCC TACAAACCAC
CCTCTCCTGA CCCTGAAGAA CTGTGTGATT CTGCCCCACA TTGGCAGTGC CACCCACAGA
ACCCGCAACA CCATGTCCTT GTTGGCAGCT AACAACTTGC TGGCTGGCCT GAGAGGGGAG
CCGATGCCTA GTGAACTCAA GCTGTAG

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

 
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