Gene Symbol | Zglp1 |
Entrez Gene ID | 100009600 |
Full Name | zinc finger, GATA-like protein 1 |
Synonyms | Glp1 |
General protein information |
|
Gene Type | protein-coding |
Organism | Mus musculus(house mouse) |
Genome |
ORF » Species Summary » Mus musculus » Zglp1 cDNA ORF clone
Gene Symbol | Zglp1 |
Entrez Gene ID | 100009600 |
Full Name | zinc finger, GATA-like protein 1 |
Synonyms | Glp1 |
General protein information |
|
Gene Type | protein-coding |
Organism | Mus musculus(house mouse) |
Genome |
mRNA | Protein | Name |
---|---|---|
NM_001103168.1 | NP_001096638.1 | GATA-type zinc finger protein 1 |
ZGLP1 | XP_001101039.2 | |
Canis lupus familiaris (dog) | ZGLP1 | XP_005632958.1 |
Homo sapiens (human) | ZGLP1 | NP_001096637.1 |
Pan troglodytes (chimpanzee) | ZGLP1 | XP_001164745.2 |
Bos taurus (cattle) | ZGLP1 | XP_002688912.2 |
Mus musculus (house mouse) | Zglp1 | NP_001096638.1 |
Rattus norvegicus (Norway rat) | Zglp1 | XP_006242739.1 |
Enhanced AMPA Receptor Trafficking Mediates the Anorexigenic Effect of Endogenous Glucagon-like Peptide-1 in the Paraventricular Hypothalamus.
Liu J, Conde K, Zhang P, Lilascharoen V, Xu Z, Lim BK, Seeley RJ, Zhu JJ, Scott MM, Pang ZP
Neuron96(4)897-909.e5(2017 Nov)
Endogenous GLP-1 as a key self-defense molecule against lipotoxicity in pancreatic islets.
Huang C, Yuan L, Cao S
International journal of molecular medicine36(1)173-85(2015 Jul)
Regulation of retinal axon growth by secreted Vax1 homeodomain protein.
Kim N, Min KW, Kang KH, Lee EJ, Kim HT, Moon K, Choi J, Le D, Lee SH, Kim JW
eLife3e02671(2014 Sep)
Role of vesicle-associated membrane protein 2 in exocytosis of glucagon-like peptide-1 from the murine intestinal L cell.
Li SK, Zhu D, Gaisano HY, Brubaker PL
Diabetologia57(4)809-18(2014 Apr)
Exendin-4 ameliorates motor neuron degeneration in cellular and animal models of amyotrophic lateral sclerosis.
Li Y, Chigurupati S, Holloway HW, Mughal M, Tweedie D, Bruestle DA, Mattson MP, Wang Y, Harvey BK, Ray B, Lahiri DK, Greig NH
PloS one7(2)e32008(2012)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
study provides a comprehensive multi-level (circuit, synaptic, and molecular) explanation of how food intake behavior and body weight are regulated by endogenous central GLP-1.
Title: Enhanced AMPA Receptor Trafficking Mediates the Anorexigenic Effect of Endogenous Glucagon-like Peptide-1 in the Paraventricular Hypothalamus.
data demonstrate an increase in number of pro-alpha cells and activation of the intra-islet GLP-1 system comprise a self-defense mechanism for enhancing beta cell survival to combat lipid overload, which is in part mediated by oxidative stress and inflammation.
Title: Endogenous GLP-1 as a key self-defense molecule against lipotoxicity in pancreatic islets.
Findings indicate an essential role for VAMP2 in GLP-1 exocytosis from the GLUTag L cell in response to a variety of established secretagogues.
Title: Role of vesicle-associated membrane protein 2 in exocytosis of glucagon-like peptide-1 from the murine intestinal L cell.
GLP-1 and analogues may provide neuroprotective actions in ALS
Title: Exendin-4 ameliorates motor neuron degeneration in cellular and animal models of amyotrophic lateral sclerosis.
Loss of GLP-1 is associated with germ cell development during embryonic oogenesis.
Title: GATA-like protein-1 (GLP-1) is required for normal germ cell development during embryonic oogenesis.
The following Zglp1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Zglp1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
CloneID | OMu03823 | |
Clone ID Related Accession (Same CDS sequence) | NM_001103168.1 | |
Accession Version | NM_001103168.1 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 801bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-01-20 | |
Organism | Mus musculus(house mouse) | |
Product | GATA-type zinc finger protein 1 | |
Comment | Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from DQ286956.1. On or before Sep 15, 2007 this sequence version replaced XM_001475156.1, XM_001475715.1. ##Evidence-Data-START## Transcript exon combination :: DQ286956.1, SRR1660811.396105.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849374, SAMN00849383 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end. |
1 | ATGGAGGCGG CACAGGCTGG AGACTTGACG CGCCGGCAGG AACTTCTGGC GCCACCTTGT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_001096638.1 |
CDS | 15..815 |
Translation |
Target ORF information:
Target ORF information:
|
NM_001103168.1 |
1 | ATGGAGGCGG CACAGGCTGG AGACTTGACG CGCCGGCAGG AACTTCTGGC GCCACCTTGT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
Enhanced AMPA Receptor Trafficking Mediates the Anorexigenic Effect of Endogenous Glucagon-like Peptide-1 in the Paraventricular Hypothalamus. |
Endogenous GLP-1 as a key self-defense molecule against lipotoxicity in pancreatic islets. |
Regulation of retinal axon growth by secreted Vax1 homeodomain protein. |
Role of vesicle-associated membrane protein 2 in exocytosis of glucagon-like peptide-1 from the murine intestinal L cell. |
Exendin-4 ameliorates motor neuron degeneration in cellular and animal models of amyotrophic lateral sclerosis. |