Gene Symbol | Gcm2 |
Entrez Gene ID | 107889 |
Full Name | glial cells missing homolog 2 |
Synonyms | Gcm-rs1,Gcm1,Gcm1-rs2 |
General protein information |
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Gene Type | protein-coding |
Organism | Mus musculus(house mouse) |
Genome |
ORF » Species Summary » Mus musculus » Gcm2 cDNA ORF clone
gRNAs
Gene Symbol | Gcm2 |
Entrez Gene ID | 107889 |
Full Name | glial cells missing homolog 2 |
Synonyms | Gcm-rs1,Gcm1,Gcm1-rs2 |
General protein information |
|
Gene Type | protein-coding |
Organism | Mus musculus(house mouse) |
Genome |
mRNA | Protein | Name |
---|---|---|
XM_017315354.1 | XP_017170843.1 | chorion-specific transcription factor GCMb isoform X1 |
NM_008104.2 | NP_032130.2 | chorion-specific transcription factor GCMb |
Xenopus tropicalis (tropical clawed frog) | gcm2 | XP_002932714.1 |
GCM2 | XP_001088392.1 | |
Rattus norvegicus (Norway rat) | Gcm2 | NP_001099575.1 |
Danio rerio (zebrafish) | gcm2 | NP_001005603.1 |
Homo sapiens (human) | GCM2 | NP_004743.1 |
Bos taurus (cattle) | GCM2 | XP_002697663.2 |
Mus musculus (house mouse) | Gcm2 | NP_032130.2 |
Gallus gallus (chicken) | GCM2 | NP_001008480.1 |
Pan troglodytes (chimpanzee) | GCM2 | XP_518235.2 |
Canis lupus familiaris (dog) | GCM2 | XP_545339.3 |
Cooperative interaction of BMP signalling and Foxn1 gene dosage determines the size of the functionally active thymic epithelial compartment.
Swann JB, Krauth B, Happe C, Boehm T
Scientific reports7(1)8492(2017 Aug)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
results suggest that MafB regulates later steps of parathyroid development, that is, separation from the thymus and migration toward the thyroid. MafB also regulates the expression of PTH in cooperation with Gcm2
Title: MafB interacts with Gcm2 and regulates parathyroid hormone expression and parathyroid development.
Gcm2 (glial cells missing 2) are involved in the epigenetic regulation of Hes5 transcription by DNA demethylation independently of DNA replication.
Title: Mammalian Gcm genes induce Hes5 expression by active DNA demethylation and induce neural stem cells.
role of Shh signalling in patterning the pharyngeal pouches and in restricting the expression of the parathyroid marker Gcm2 in the pharyngeal epithelium
Title: Shh signalling restricts the expression of Gcm2 and controls the position of the developing parathyroids.
Gcm2 is required for the differentiation and survival of parathyroid precursor cells in the parathyroid/thymus primordia.
Title: Gcm2 is required for the differentiation and survival of parathyroid precursor cells in the parathyroid/thymus primordia.
GCM domain as a new type of Zn-coordinating, sequence-specific DNA-binding domain.
Title: The GCM domain is a Zn-coordinating DNA-binding domain.
The following Gcm2 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Gcm2 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
CloneID | OMu17969 | |
Clone ID Related Accession (Same CDS sequence) | NM_008104.2 | |
Accession Version | NM_008104.2 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1515bp) Protein sequence SNP |
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Vector | pcDNA3.1-C-(k)DYK or customized vector | ![]() |
Clone information | Clone Map | ![]() |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-12-24 | |
Organism | Mus musculus(house mouse) | |
Product | chorion-specific transcription factor GCMb | |
Comment | Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AC158538.2, AF081556.1 and BG070860.2. On Aug 31, 2006 this sequence version replaced NM_008104.1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: D88611.1, BC110631.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849374, SAMN01164142 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end. |
1 | ATGCCAGCAG ACAGCACGCA GGACGAGGAT GCTGTGCTCT CCTACGGGAT GAAACTCACG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_032130.2 |
CDS | 35..1549 |
Translation |
Target ORF information:
Target ORF information:
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1 | ATGCCAGCAG ACAGCACGCA GGACGAGGAT GCTGTGCTCT CCTACGGGAT GAAACTCACG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OMu78405 | |
Clone ID Related Accession (Same CDS sequence) | XM_017315354.1 | |
Accession Version | XM_017315354.1 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 609bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | ![]() |
Clone information | Clone Map | ![]() |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-08-07 | |
Organism | Mus musculus(house mouse) | |
Product | chorion-specific transcription factor GCMb isoform X1 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000079.6) annotated using gene prediction method: Gnomon, supported by mRNA evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Mus musculus Annotation Release 108 Annotation Version :: 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGCCAGCAG ACAGCACGCA GGACGAGGAT GCTGTGCTCT CCTACGGGAT GAAACTCACG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_017170843.1 |
CDS | 140..748 |
Translation |
Target ORF information:
Target ORF information:
|
![]() |
1 | ATGCCAGCAG ACAGCACGCA GGACGAGGAT GCTGTGCTCT CCTACGGGAT GAAACTCACG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
Cooperative interaction of BMP signalling and Foxn1 gene dosage determines the size of the functionally active thymic epithelial compartment. |