Gene Symbol | Cdk9 |
Entrez Gene ID | 107951 |
Full Name | cyclin-dependent kinase 9 (CDC2-related kinase) |
Synonyms | PITALRE |
General protein information |
|
Gene Type | protein-coding |
Organism | Mus musculus(house mouse) |
Genome |
ORF » Species Summary » Mus musculus » Cdk9 cDNA ORF clone
Gene Symbol | Cdk9 |
Entrez Gene ID | 107951 |
Full Name | cyclin-dependent kinase 9 (CDC2-related kinase) |
Synonyms | PITALRE |
General protein information |
|
Gene Type | protein-coding |
Organism | Mus musculus(house mouse) |
Genome |
mRNA | Protein | Name |
---|---|---|
XM_011239001.1 | XP_011237303.1 | cyclin-dependent kinase 9 isoform X1 |
NM_130860.3 | NP_570930.1 | cyclin-dependent kinase 9 |
CDK9 | XP_001094626.1 | |
Mus musculus (house mouse) | Cdk9 | NP_570930.1 |
Gallus gallus (chicken) | CDK9 | NP_001006201.1 |
Caenorhabditis elegans (roundworm) | cdk-9 | NP_492906.2 |
Homo sapiens (human) | CDK9 | NP_001252.1 |
Pan troglodytes (chimpanzee) | CDK9 | XP_520277.2 |
Danio rerio (zebrafish) | cdk9 | NP_997756.1 |
Schizosaccharomyces pombe (fission yeast) | cdk9 | NP_595616.1 |
Canis lupus familiaris (dog) | CDK9 | XP_003639361.2 |
Rattus norvegicus (Norway rat) | Cdk9 | NP_001007744.1 |
Drosophila melanogaster (fruit fly) | Cdk9 | NP_477226.2 |
Anopheles gambiae (African malaria mosquito) | AgaP_AGAP008541 | XP_314652.2 |
Xenopus tropicalis (tropical clawed frog) | cdk9 | NP_001005448.1 |
Bos taurus (cattle) | CDK9 | NP_001014935.2 |
Glucocorticoid-induced phosphorylation by CDK9 modulates the coactivator functions of transcriptional cofactor GRIP1 in macrophages.
Rollins DA, Kharlyngdoh JB, Coppo M, Tharmalingam B, Mimouna S, Guo Z, Sacta MA, Pufall MA, Fisher RP, Hu X, Chinenov Y, Rogatsky I
Nature communications8(1)1739(2017 Nov)
BRD4 regulates adiponectin gene induction by recruiting the P-TEFb complex to the transcribed region of the gene.
Sakurai N, Inamochi Y, Inoue T, Hariya N, Kawamura M, Yamada M, Dey A, Nishiyama A, Kubota T, Ozato K, Goda T, Mochizuki K
Scientific reports7(1)11962(2017 Sep)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
findings revealed the crucial role of CDK9/Cyclin T1/Pol II pathway in promoting allorejection at multiple levels and may provide a new approach for transplantation tolerance induction through targeting CDK9
Title: Down-regulating cyclin-dependent kinase 9 of alloreactive CD4+ T cells prolongs allograft survival.
identified cyclin-dependent kinase 9 (Cdk9) as required for hepatocellular carcinoma disease maintenance
Title: CDK9-mediated transcription elongation is required for MYC addiction in hepatocellular carcinoma.
This study demonstrates that Ikaros directly interacts with GATA1, GATA2, and GATA3 as well as Cdk9/P-TEFb through specific protein domains.
Title: Direct protein interactions are responsible for Ikaros-GATA and Ikaros-Cdk9 cooperativeness in hematopoietic cells.
Data show that the minimal 90-amino acid AF9 fragment in MLL-AF9 retains an ability to form higher order complexes with AF4*P-TEFb and with DOT1.
Title: Function of leukemogenic mixed lineage leukemia 1 (MLL) fusion proteins through distinct partner protein complexes.
Data show that the CDK9 and cyclin T1 subunits of P-TEFb are present in mouse oocytes and preimplantation embryos, and that CDK9 is essential for embryonic genome activation in the mouse.
Title: The CDK9/cyclin T1 subunits of P-TEFb in mouse oocytes and preimplantation embryos: a possible role in embryonic genome activation.
The following Cdk9 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Cdk9 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
CloneID | OMu21163 | |
Clone ID Related Accession (Same CDS sequence) | NM_130860.3 | |
Accession Version | NM_130860.3 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1119bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-12-26 | |
Organism | Mus musculus(house mouse) | |
Product | cyclin-dependent kinase 9 | |
Comment | Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AK143217.1 and AL772271.11. On Nov 24, 2007 this sequence version replaced NM_130860.2. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AK143217.1, AK144607.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN01164131, SAMN01164139 [ECO:0000348] ##Evidence-Data-END## |
1 | ATGGCCAAGC AGTACGACTC GGTGGAATGC CCGTTCTGCG ATGAGGTCAC CAAGTACGAG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_570930.1 |
CDS | 129..1247 |
Translation |
Target ORF information:
Target ORF information:
|
NM_130860.3 |
1 | ATGGCCAAGC AGTACGACTC GGTGGAATGC CCGTTCTGCG ATGAGGTCAC CAAGTACGAG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OMu72199 | |
Clone ID Related Accession (Same CDS sequence) | XM_011239001.1 | |
Accession Version | XM_011239001.1 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 732bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-08-07 | |
Organism | Mus musculus(house mouse) | |
Product | cyclin-dependent kinase 9 isoform X1 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000068.7) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Mus musculus Annotation Release 108 Annotation Version :: 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGCAGATGC TGCTGAACGG CCTCTACTAC ATCCACAGGA ACAAGATCCT GCACAGGGAC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_011237303.1 |
CDS | 713..1444 |
Translation |
Target ORF information:
Target ORF information:
|
XM_011239001.1 |
1 | ATGCAGATGC TGCTGAACGG CCTCTACTAC ATCCACAGGA ACAAGATCCT GCACAGGGAC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
Glucocorticoid-induced phosphorylation by CDK9 modulates the coactivator functions of transcriptional cofactor GRIP1 in macrophages. |
BRD4 regulates adiponectin gene induction by recruiting the P-TEFb complex to the transcribed region of the gene. |