| Gene Symbol | Amd1 |
| Entrez Gene ID | 11702 |
| Full Name | S-adenosylmethionine decarboxylase 1 |
| Synonyms | AdoMetDC,Amd-1,SAMDC,SAMDC 1,adoMetDC1 |
| General protein information |
|
| Gene Type | protein-coding |
| Organism | Mus musculus(house mouse) |
| Genome |
gRNAs
The following Amd1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Amd1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
| CloneID | OMu18403 | |
| Clone ID Related Accession (Same CDS sequence) | NM_009665.5 | |
| Accession Version | NM_009665.5 Latest version! | Documents for ORF clone product in default vector |
| Sequence Information | ORF Nucleotide Sequence (Length: 1005bp) Protein sequence SNP |
|
| Vector | pcDNA3.1-C-(k)DYK or customized vector |  User Manual |
| Clone information | Clone Map | MSDS |
| Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
| ORF Insert Method | CloneEZ™ Seamless cloning technology | |
| Insert Structure | linear | |
| Update Date | 2019-12-26 | |
| Organism | Mus musculus(house mouse) | |
| Product | S-adenosylmethionine decarboxylase proenzyme 1 | |
| Comment | Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AC142273.3 and AK146840.1. On Mar 19, 2011 this sequence version replaced NM_009665.4. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC011110.1, AK146840.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMN00849374, SAMN00849375 [ECO:0000350] ##Evidence-Data-END## ##RefSeq-Attributes-START## regulatory uORF :: PMID: 10829027 ##RefSeq-Attributes-END## COMPLETENESS: complete on the 3' end. | |
1 | ATGGAAGCTG CACATTTTTT CGAAGGGACG GAGAAACTGC TGGAGGTCTG GTTTTCCAGA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
| RefSeq | NP_033795.1 |
| CDS | 331..1335 |
| Translation |
Target ORF information:
Target ORF information:
|
 NM_009665.5 |
1 | ATGGAAGCTG CACATTTTTT CGAAGGGACG GAGAAACTGC TGGAGGTCTG GTTTTCCAGA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
Inhibition of polyamine synthesis causes entry of the mouse blastocyst into embryonic diapause. |
AMD1 is essential for ESC self-renewal and is translationally down-regulated on differentiation to neural precursor cells. |
Transcriptomic analysis of polyamine-related genes and polyamine levels in placenta, yolk sac and fetus during the second half of mouse pregnancy. |
Molecular and morphological changes in placenta and embryo development associated with the inhibition of polyamine synthesis during midpregnancy in mice. |
Regulated translation termination at the upstream open reading frame in s-adenosylmethionine decarboxylase mRNA. |
