Apobec1 cDNA ORF clone, Mus musculus(house mouse)

Gene
Clones
gRNAs

Gene Symbol	Apobec1
Entrez Gene ID	11810
Full Name	apolipoprotein B mRNA editing enzyme, catalytic polypeptide 1
Synonyms	Cdar1
General protein information	Preferred Names apolipoprotein B mRNA editing enzyme, catalytic polypeptide 1 Names C->U-editing enzyme APOBEC-1 apolipoprotein B editing complex 1 mRNA(cytosine(6666)) deaminase 1
Gene Type	protein-coding
Organism	Mus musculus(house mouse)
Genome	Chromosome: 6 Map Location: 6 F1\|6 57.68 cM

mRNA and Protein(s)

mRNA	Protein	Name
XM_006505401.2	XP_006505464.1	C->U-editing enzyme APOBEC-1 isoform X1
XM_011241159.3	XP_011239461.1	C->U-editing enzyme APOBEC-1 isoform X1
XM_011241159.2	XP_011239461.1	C->U-editing enzyme APOBEC-1 isoform X1
NM_001134391.1	NP_001127863.1	C->U-editing enzyme APOBEC-1
XM_006505401.3	XP_006505464.1	C->U-editing enzyme APOBEC-1 isoform X1
NM_031159.3	NP_112436.1	C->U-editing enzyme APOBEC-1

Pathways from BioSystems

Homologies

Pan troglodytes (chimpanzee)	APOBEC1	XP_001164661.1
	APOBEC1	XP_001112583.1
Rattus norvegicus (Norway rat)	Apobec1	NP_037039.1
Homo sapiens (human)	APOBEC1	NP_001635.2
Canis lupus familiaris (dog)	APOBEC1	XP_543826.2
Mus musculus (house mouse)	Apobec1	NP_112436.1
Bos taurus (cattle)	APOBEC1	XP_002687863.1

Gene Ontology
Bibliography

Related articles in PubMed

Role of angiopoietin-like 3 (ANGPTL3) in regulating plasma level of low-density lipoprotein cholesterol.
Xu YX, Redon V, Yu H, Querbes W, Pirruccello J, Liebow A, Deik A, Trindade K, Wang X, Musunuru K, Clish CB, Cowan C, Fizgerald K, Rader D, Kathiresan S
Atherosclerosis268196-206(2018 Jan)

Loss of APOBEC1 RNA-editing function in microglia exacerbates age-related CNS pathophysiology.
Cole DC, Chung Y, Gagnidze K, Hajdarovic KH, Rayon-Estrada V, Harjanto D, Bigio B, Gal-Toth J, Milner TA, McEwen BS, Papavasiliou FN, Bulloch K
Proceedings of the National Academy of Sciences of the United States of America114(50)13272-13277(2017 Dec)

Do Gametes Woo? Evidence for Their Nonrandom Union at Fertilization.
Nadeau JH
Genetics207(2)369-387(2017 Oct)

A human APOC3 missense variant and monoclonal antibody accelerate apoC-III clearance and lower triglyceride-rich lipoprotein levels.
Khetarpal SA, Zeng X, Millar JS, Vitali C, Somasundara AVH, Zanoni P, Landro JA, Barucci N, Zavadoski WJ, Sun Z, de Haard H, Toth IV, Peloso GM, Natarajan P, Cuchel M, Lund-Katz S, Phillips MC, Tall AR, Kathiresan S, DaSilva-Jardine P, Yates NA, Rader DJ
Nature medicine23(9)1086-1094(2017 Sep)

Development of an efficient screening system to identify novel bone metabolism-related genes using the exchangeable gene trap mutagenesis mouse models.
Kurogi S, Sekimoto T, Funamoto T, Ota T, Nakamura S, Nagai T, Nakahara M, Yoshinobu K, Araki K, Araki M, Chosa E
Scientific reports740692(2017 Jan)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The observations demonstrate that A1CF does not act as the APOBEC1 complementation factor in vivo under normal physiological conditions and suggest new roles for A1CF, specifically within the male adult kidney.
Title: APOBEC1 complementation factor (A1CF) is dispensable for C-to-U RNA editing in vivo.

substantial rearrangement/duplication of transgene elements is present, and transgene integration was accompanied by the deletion of a 19,500 bp fragment of genomic DNA that contains the promoter, exon 1 and part of intron 1 of the APOBEC1 complementation factor (A1cf) gene, as well as several elements that are predicted to regulate chromosomal architecture
Title: Chromosomal mapping of the ?MHC-MerCreMer transgene in mice reveals a large genomic deletion.

In contrast to in vitro results, APOBEC1 neither inhibited nor significantly drove the molecular evolution of Friend retrovirus in wild type or APOBEC1 knockout mice.
Title: Reassessment of murine APOBEC1 as a retrovirus restriction factor in vivo.

RBM47 and APOBEC1 constitute the basic machinery for C to U RNA editing.
Title: C to U RNA editing mediated by APOBEC1 requires RNA-binding protein RBM47.

Apobec-1-dependent C-to-U RNA editing exerts broad functional effects in a tissue-specific manner.
Title: Genome-wide identification and functional analysis of Apobec-1-mediated C-to-U RNA editing in mouse small intestine and liver.

The following Apobec1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Apobec1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OMu16016	NM_031159.3 Latest version!	Mus musculus apolipoprotein B mRNA editing enzyme, catalytic polypeptide 1 (Apobec1), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$139.30 $199.00
OMu16016	NM_001134391.1 Latest version!	Mus musculus apolipoprotein B mRNA editing enzyme, catalytic polypeptide 1 (Apobec1), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$139.30 $199.00
OMu16016	XM_006505401.3 Latest version!	Mus musculus apolipoprotein B mRNA editing enzyme, catalytic polypeptide 1 (Apobec1), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$139.30 $199.00
OMu16016	XM_011241159.3 Latest version!	Mus musculus apolipoprotein B mRNA editing enzyme, catalytic polypeptide 1 (Apobec1), transcript variant X2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$139.30 $199.00
View Old Accession Versions >>
OMu16016	XM_011241159.2	Mus musculus apolipoprotein B mRNA editing enzyme, catalytic polypeptide 1 (Apobec1), transcript variant X2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$139.30 $199.00
OMu16016	XM_006505401.2	Mus musculus apolipoprotein B mRNA editing enzyme, catalytic polypeptide 1 (Apobec1), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$139.30 $199.00
Hide Old Accession Versions >>

ORF Online Only Promotion

Next-day Shipping ORF Clones ( in default vector with tag)
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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Apobec1 ( NM_001134391.1 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_001127863.1 Mus musculus apolipoprotein B mRNA editing enzyme, catalytic polypeptide 1 (Apobec1), transcript variant 2, mRNA.

Price & Availability↑

CloneID	OMu16016
Clone ID Related Accession (Same CDS sequence)	XM_006505401.2 , XM_011241159.3 , XM_011241159.2 , NM_001134391.1 , XM_006505401.3 , NM_031159.3
Accession Version	NM_001134391.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 690bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-16
Organism	Mus musculus(house mouse)
Product	C->U-editing enzyme APOBEC-1
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AC158651.12, AK151799.1 and BE634918.1. Transcript Variant: This variant (2) differs in the 5' UTR, compared to variant 1. Variants 1 and 2 encode the same protein. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: U22263.1, AK151799.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849380, SAMN00849382 [ECO:0000348] ##Evidence-Data-END##

ATGAGTTCCG AGACAGGCCC TGTAGCTGTT GATCCCACTC TGAGGAGAAG AATTGAGCCC 
CACGAGTTTG AAGTCTTCTT TGACCCCCGG GAGCTTCGGA AAGAGACCTG TCTGCTGTAT 
GAGATCAACT GGGGTGGAAG GCACAGTGTC TGGCGACACA CGAGCCAAAA CACCAGCAAC 
CACGTTGAAG TCAACTTCTT AGAAAAATTT ACTACAGAAA GATACTTTCG TCCGAACACC 
AGATGCTCCA TTACCTGGTT CCTGTCCTGG AGTCCCTGCG GGGAGTGCTC CAGGGCCATT 
ACAGAGTTTC TGAGCCGACA CCCCTATGTA ACTCTGTTTA TTTACATAGC ACGGCTTTAT 
CACCACACGG ATCAGCGAAA CCGCCAAGGA CTCAGGGACC TTATTAGCAG CGGTGTGACT 
ATCCAGATCA TGACAGAGCA AGAGTATTGT TACTGCTGGA GGAATTTCGT CAACTACCCC 
CCTTCAAACG AAGCTTATTG GCCAAGGTAC CCCCATCTGT GGGTGAAACT GTATGTACTG 
GAGCTCTACT GCATCATTTT AGGACTTCCA CCCTGTTTAA AAATTTTAAG AAGAAAGCAA 
CCTCAACTCA CGTTTTTCAC AATTACTCTT CAAACCTGCC ATTACCAAAG GATACCACCC 
CATCTCCTTT GGGCTACAGG GTTGAAATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001127863.1
CDS	505..1194
Translation	MSSETGPVAVDPTLRRRIEPHEFEVFFDPRELRKETCLLYEINWGGRHSVWRHTSQNTSNHVEVNFLEKFTTERYFRPNTRCSITWFLSWSPCGECSRAITEFLSRHPYVTLFIYIARLYHHTDQRNRQGLRDLISSGVTIQIMTEQEYCYCWRNFVNYPPSNEAYWPRYPHLWVKLYVLELYCIILGLPPCLKILRRKQPQLTFFTITLQTCHYQRIPPHLLWATGLK

Target ORF information:

RefSeq Version	NM_001134391.1
Organism	Mus musculus(house mouse)
Definition	Mus musculus apolipoprotein B mRNA editing enzyme, catalytic polypeptide 1 (Apobec1), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001134391.1

ORF Insert Sequence:

ATGAGTTCCG AGACAGGCCC TGTAGCTGTT GATCCCACTC TGAGGAGAAG AATTGAGCCC 
CACGAGTTTG AAGTCTTCTT TGACCCCCGG GAGCTTCGGA AAGAGACCTG TCTGCTGTAT 
GAGATCAACT GGGGTGGAAG GCACAGTGTC TGGCGACACA CGAGCCAAAA CACCAGCAAC 
CACGTTGAAG TCAACTTCTT AGAAAAATTT ACTACAGAAA GATACTTTCG TCCGAACACC 
AGATGCTCCA TTACCTGGTT CCTGTCCTGG AGTCCCTGCG GGGAGTGCTC CAGGGCCATT 
ACAGAGTTTC TGAGCCGACA CCCCTATGTA ACTCTGTTTA TTTACATAGC ACGGCTTTAT 
CACCACACGG ATCAGCGAAA CCGCCAAGGA CTCAGGGACC TTATTAGCAG CGGTGTGACT 
ATCCAGATCA TGACAGAGCA AGAGTATTGT TACTGCTGGA GGAATTTCGT CAACTACCCC 
CCTTCAAACG AAGCTTATTG GCCAAGGTAC CCCCATCTGT GGGTGAAACT GTATGTACTG 
GAGCTCTACT GCATCATTTT AGGACTTCCA CCCTGTTTAA AAATTTTAAG AAGAAAGCAA 
CCTCAACTCA CGTTTTTCAC AATTACTCTT CAAACCTGCC ATTACCAAAG GATACCACCC 
CATCTCCTTT GGGCTACAGG GTTGAAATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Apobec1 ( NM_031159.3 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_112436.1 Mus musculus apolipoprotein B mRNA editing enzyme, catalytic polypeptide 1 (Apobec1), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OMu16016
Clone ID Related Accession (Same CDS sequence)	XM_006505401.2 , XM_011241159.3 , XM_011241159.2 , NM_001134391.1 , XM_006505401.3 , NM_031159.3
Accession Version	NM_031159.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 690bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-16
Organism	Mus musculus(house mouse)
Product	C->U-editing enzyme APOBEC-1
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AC158651.12. On Nov 17, 2006 this sequence version replaced NM_031159.2. Transcript Variant: This variant (1) represents the longer transcript. Variants 1 and 2 encode the same protein. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: U22262.1, AK146427.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMN00849374, SAMN00849375 [ECO:0000350] ##Evidence-Data-END##

ATGAGTTCCG AGACAGGCCC TGTAGCTGTT GATCCCACTC TGAGGAGAAG AATTGAGCCC 
CACGAGTTTG AAGTCTTCTT TGACCCCCGG GAGCTTCGGA AAGAGACCTG TCTGCTGTAT 
GAGATCAACT GGGGTGGAAG GCACAGTGTC TGGCGACACA CGAGCCAAAA CACCAGCAAC 
CACGTTGAAG TCAACTTCTT AGAAAAATTT ACTACAGAAA GATACTTTCG TCCGAACACC 
AGATGCTCCA TTACCTGGTT CCTGTCCTGG AGTCCCTGCG GGGAGTGCTC CAGGGCCATT 
ACAGAGTTTC TGAGCCGACA CCCCTATGTA ACTCTGTTTA TTTACATAGC ACGGCTTTAT 
CACCACACGG ATCAGCGAAA CCGCCAAGGA CTCAGGGACC TTATTAGCAG CGGTGTGACT 
ATCCAGATCA TGACAGAGCA AGAGTATTGT TACTGCTGGA GGAATTTCGT CAACTACCCC 
CCTTCAAACG AAGCTTATTG GCCAAGGTAC CCCCATCTGT GGGTGAAACT GTATGTACTG 
GAGCTCTACT GCATCATTTT AGGACTTCCA CCCTGTTTAA AAATTTTAAG AAGAAAGCAA 
CCTCAACTCA CGTTTTTCAC AATTACTCTT CAAACCTGCC ATTACCAAAG GATACCACCC 
CATCTCCTTT GGGCTACAGG GTTGAAATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_112436.1
CDS	561..1250
Translation	MSSETGPVAVDPTLRRRIEPHEFEVFFDPRELRKETCLLYEINWGGRHSVWRHTSQNTSNHVEVNFLEKFTTERYFRPNTRCSITWFLSWSPCGECSRAITEFLSRHPYVTLFIYIARLYHHTDQRNRQGLRDLISSGVTIQIMTEQEYCYCWRNFVNYPPSNEAYWPRYPHLWVKLYVLELYCIILGLPPCLKILRRKQPQLTFFTITLQTCHYQRIPPHLLWATGLK

Target ORF information:

RefSeq Version	NM_031159.3
Organism	Mus musculus(house mouse)
Definition	Mus musculus apolipoprotein B mRNA editing enzyme, catalytic polypeptide 1 (Apobec1), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_031159.3

ORF Insert Sequence:

ATGAGTTCCG AGACAGGCCC TGTAGCTGTT GATCCCACTC TGAGGAGAAG AATTGAGCCC 
CACGAGTTTG AAGTCTTCTT TGACCCCCGG GAGCTTCGGA AAGAGACCTG TCTGCTGTAT 
GAGATCAACT GGGGTGGAAG GCACAGTGTC TGGCGACACA CGAGCCAAAA CACCAGCAAC 
CACGTTGAAG TCAACTTCTT AGAAAAATTT ACTACAGAAA GATACTTTCG TCCGAACACC 
AGATGCTCCA TTACCTGGTT CCTGTCCTGG AGTCCCTGCG GGGAGTGCTC CAGGGCCATT 
ACAGAGTTTC TGAGCCGACA CCCCTATGTA ACTCTGTTTA TTTACATAGC ACGGCTTTAT 
CACCACACGG ATCAGCGAAA CCGCCAAGGA CTCAGGGACC TTATTAGCAG CGGTGTGACT 
ATCCAGATCA TGACAGAGCA AGAGTATTGT TACTGCTGGA GGAATTTCGT CAACTACCCC 
CCTTCAAACG AAGCTTATTG GCCAAGGTAC CCCCATCTGT GGGTGAAACT GTATGTACTG 
GAGCTCTACT GCATCATTTT AGGACTTCCA CCCTGTTTAA AAATTTTAAG AAGAAAGCAA 
CCTCAACTCA CGTTTTTCAC AATTACTCTT CAAACCTGCC ATTACCAAAG GATACCACCC 
CATCTCCTTT GGGCTACAGG GTTGAAATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Apobec1 ( XM_006505401.2 ) cDNA ORF clone, Mus musculus(house mouse) -> XP_006505464.1 Mus musculus apolipoprotein B mRNA editing enzyme, catalytic polypeptide 1 (Apobec1), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OMu16016
Clone ID Related Accession (Same CDS sequence)	XM_006505401.2 , XM_011241159.3 , XM_011241159.2 , NM_001134391.1 , XM_006505401.3 , NM_031159.3
Accession Version	XM_006505401.2	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 690bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-06-21
Organism	Mus musculus(house mouse)
Product	C->U-editing enzyme APOBEC-1 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000072.6) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Feb 9, 2015 this sequence version replaced XM_006505401.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Mus musculus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGAGTTCCG AGACAGGCCC TGTAGCTGTT GATCCCACTC TGAGGAGAAG AATTGAGCCC 
CACGAGTTTG AAGTCTTCTT TGACCCCCGG GAGCTTCGGA AAGAGACCTG TCTGCTGTAT 
GAGATCAACT GGGGTGGAAG GCACAGTGTC TGGCGACACA CGAGCCAAAA CACCAGCAAC 
CACGTTGAAG TCAACTTCTT AGAAAAATTT ACTACAGAAA GATACTTTCG TCCGAACACC 
AGATGCTCCA TTACCTGGTT CCTGTCCTGG AGTCCCTGCG GGGAGTGCTC CAGGGCCATT 
ACAGAGTTTC TGAGCCGACA CCCCTATGTA ACTCTGTTTA TTTACATAGC ACGGCTTTAT 
CACCACACGG ATCAGCGAAA CCGCCAAGGA CTCAGGGACC TTATTAGCAG CGGTGTGACT 
ATCCAGATCA TGACAGAGCA AGAGTATTGT TACTGCTGGA GGAATTTCGT CAACTACCCC 
CCTTCAAACG AAGCTTATTG GCCAAGGTAC CCCCATCTGT GGGTGAAACT GTATGTACTG 
GAGCTCTACT GCATCATTTT AGGACTTCCA CCCTGTTTAA AAATTTTAAG AAGAAAGCAA 
CCTCAACTCA CGTTTTTCAC AATTACTCTT CAAACCTGCC ATTACCAAAG GATACCACCC 
CATCTCCTTT GGGCTACAGG GTTGAAATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006505464.1
CDS	1271..1960
Translation	MSSETGPVAVDPTLRRRIEPHEFEVFFDPRELRKETCLLYEINWGGRHSVWRHTSQNTSNHVEVNFLEKFTTERYFRPNTRCSITWFLSWSPCGECSRAITEFLSRHPYVTLFIYIARLYHHTDQRNRQGLRDLISSGVTIQIMTEQEYCYCWRNFVNYPPSNEAYWPRYPHLWVKLYVLELYCIILGLPPCLKILRRKQPQLTFFTITLQTCHYQRIPPHLLWATGLK

Target ORF information:

RefSeq Version	XM_006505401.2
Organism	Mus musculus(house mouse)
Definition	Mus musculus apolipoprotein B mRNA editing enzyme, catalytic polypeptide 1 (Apobec1), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006505401.2

ORF Insert Sequence:

ATGAGTTCCG AGACAGGCCC TGTAGCTGTT GATCCCACTC TGAGGAGAAG AATTGAGCCC 
CACGAGTTTG AAGTCTTCTT TGACCCCCGG GAGCTTCGGA AAGAGACCTG TCTGCTGTAT 
GAGATCAACT GGGGTGGAAG GCACAGTGTC TGGCGACACA CGAGCCAAAA CACCAGCAAC 
CACGTTGAAG TCAACTTCTT AGAAAAATTT ACTACAGAAA GATACTTTCG TCCGAACACC 
AGATGCTCCA TTACCTGGTT CCTGTCCTGG AGTCCCTGCG GGGAGTGCTC CAGGGCCATT 
ACAGAGTTTC TGAGCCGACA CCCCTATGTA ACTCTGTTTA TTTACATAGC ACGGCTTTAT 
CACCACACGG ATCAGCGAAA CCGCCAAGGA CTCAGGGACC TTATTAGCAG CGGTGTGACT 
ATCCAGATCA TGACAGAGCA AGAGTATTGT TACTGCTGGA GGAATTTCGT CAACTACCCC 
CCTTCAAACG AAGCTTATTG GCCAAGGTAC CCCCATCTGT GGGTGAAACT GTATGTACTG 
GAGCTCTACT GCATCATTTT AGGACTTCCA CCCTGTTTAA AAATTTTAAG AAGAAAGCAA 
CCTCAACTCA CGTTTTTCAC AATTACTCTT CAAACCTGCC ATTACCAAAG GATACCACCC 
CATCTCCTTT GGGCTACAGG GTTGAAATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Apobec1 ( XM_011241159.2 ) cDNA ORF clone, Mus musculus(house mouse) -> XP_011239461.1 Mus musculus apolipoprotein B mRNA editing enzyme, catalytic polypeptide 1 (Apobec1), transcript variant X2, mRNA.

Price & Availability↑

CloneID	OMu16016
Clone ID Related Accession (Same CDS sequence)	XM_006505401.2 , XM_011241159.3 , XM_011241159.2 , NM_001134391.1 , XM_006505401.3 , NM_031159.3
Accession Version	XM_011241159.2	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 690bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-06-21
Organism	Mus musculus(house mouse)
Product	C->U-editing enzyme APOBEC-1 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000072.6) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 22, 2016 this sequence version replaced XM_011241159.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Mus musculus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGAGTTCCG AGACAGGCCC TGTAGCTGTT GATCCCACTC TGAGGAGAAG AATTGAGCCC 
CACGAGTTTG AAGTCTTCTT TGACCCCCGG GAGCTTCGGA AAGAGACCTG TCTGCTGTAT 
GAGATCAACT GGGGTGGAAG GCACAGTGTC TGGCGACACA CGAGCCAAAA CACCAGCAAC 
CACGTTGAAG TCAACTTCTT AGAAAAATTT ACTACAGAAA GATACTTTCG TCCGAACACC 
AGATGCTCCA TTACCTGGTT CCTGTCCTGG AGTCCCTGCG GGGAGTGCTC CAGGGCCATT 
ACAGAGTTTC TGAGCCGACA CCCCTATGTA ACTCTGTTTA TTTACATAGC ACGGCTTTAT 
CACCACACGG ATCAGCGAAA CCGCCAAGGA CTCAGGGACC TTATTAGCAG CGGTGTGACT 
ATCCAGATCA TGACAGAGCA AGAGTATTGT TACTGCTGGA GGAATTTCGT CAACTACCCC 
CCTTCAAACG AAGCTTATTG GCCAAGGTAC CCCCATCTGT GGGTGAAACT GTATGTACTG 
GAGCTCTACT GCATCATTTT AGGACTTCCA CCCTGTTTAA AAATTTTAAG AAGAAAGCAA 
CCTCAACTCA CGTTTTTCAC AATTACTCTT CAAACCTGCC ATTACCAAAG GATACCACCC 
CATCTCCTTT GGGCTACAGG GTTGAAATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_011239461.1
CDS	469..1158
Translation	MSSETGPVAVDPTLRRRIEPHEFEVFFDPRELRKETCLLYEINWGGRHSVWRHTSQNTSNHVEVNFLEKFTTERYFRPNTRCSITWFLSWSPCGECSRAITEFLSRHPYVTLFIYIARLYHHTDQRNRQGLRDLISSGVTIQIMTEQEYCYCWRNFVNYPPSNEAYWPRYPHLWVKLYVLELYCIILGLPPCLKILRRKQPQLTFFTITLQTCHYQRIPPHLLWATGLK

Target ORF information:

RefSeq Version	XM_011241159.2
Organism	Mus musculus(house mouse)
Definition	Mus musculus apolipoprotein B mRNA editing enzyme, catalytic polypeptide 1 (Apobec1), transcript variant X2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_011241159.2

ORF Insert Sequence:

ATGAGTTCCG AGACAGGCCC TGTAGCTGTT GATCCCACTC TGAGGAGAAG AATTGAGCCC 
CACGAGTTTG AAGTCTTCTT TGACCCCCGG GAGCTTCGGA AAGAGACCTG TCTGCTGTAT 
GAGATCAACT GGGGTGGAAG GCACAGTGTC TGGCGACACA CGAGCCAAAA CACCAGCAAC 
CACGTTGAAG TCAACTTCTT AGAAAAATTT ACTACAGAAA GATACTTTCG TCCGAACACC 
AGATGCTCCA TTACCTGGTT CCTGTCCTGG AGTCCCTGCG GGGAGTGCTC CAGGGCCATT 
ACAGAGTTTC TGAGCCGACA CCCCTATGTA ACTCTGTTTA TTTACATAGC ACGGCTTTAT 
CACCACACGG ATCAGCGAAA CCGCCAAGGA CTCAGGGACC TTATTAGCAG CGGTGTGACT 
ATCCAGATCA TGACAGAGCA AGAGTATTGT TACTGCTGGA GGAATTTCGT CAACTACCCC 
CCTTCAAACG AAGCTTATTG GCCAAGGTAC CCCCATCTGT GGGTGAAACT GTATGTACTG 
GAGCTCTACT GCATCATTTT AGGACTTCCA CCCTGTTTAA AAATTTTAAG AAGAAAGCAA 
CCTCAACTCA CGTTTTTCAC AATTACTCTT CAAACCTGCC ATTACCAAAG GATACCACCC 
CATCTCCTTT GGGCTACAGG GTTGAAATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Apobec1 ( XM_011241159.3 ) cDNA ORF clone, Mus musculus(house mouse) -> XP_011239461.1 Mus musculus apolipoprotein B mRNA editing enzyme, catalytic polypeptide 1 (Apobec1), transcript variant X2, mRNA.

Price & Availability↑

CloneID	OMu16016
Clone ID Related Accession (Same CDS sequence)	XM_006505401.2 , XM_011241159.3 , XM_011241159.2 , NM_001134391.1 , XM_006505401.3 , NM_031159.3
Accession Version	XM_011241159.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 690bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-08-07
Organism	Mus musculus(house mouse)
Product	C->U-editing enzyme APOBEC-1 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000072.6) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Aug 8, 2019 this sequence version replaced XM_011241159.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Mus musculus Annotation Release 108 Annotation Version :: 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGAGTTCCG AGACAGGCCC TGTAGCTGTT GATCCCACTC TGAGGAGAAG AATTGAGCCC 
CACGAGTTTG AAGTCTTCTT TGACCCCCGG GAGCTTCGGA AAGAGACCTG TCTGCTGTAT 
GAGATCAACT GGGGTGGAAG GCACAGTGTC TGGCGACACA CGAGCCAAAA CACCAGCAAC 
CACGTTGAAG TCAACTTCTT AGAAAAATTT ACTACAGAAA GATACTTTCG TCCGAACACC 
AGATGCTCCA TTACCTGGTT CCTGTCCTGG AGTCCCTGCG GGGAGTGCTC CAGGGCCATT 
ACAGAGTTTC TGAGCCGACA CCCCTATGTA ACTCTGTTTA TTTACATAGC ACGGCTTTAT 
CACCACACGG ATCAGCGAAA CCGCCAAGGA CTCAGGGACC TTATTAGCAG CGGTGTGACT 
ATCCAGATCA TGACAGAGCA AGAGTATTGT TACTGCTGGA GGAATTTCGT CAACTACCCC 
CCTTCAAACG AAGCTTATTG GCCAAGGTAC CCCCATCTGT GGGTGAAACT GTATGTACTG 
GAGCTCTACT GCATCATTTT AGGACTTCCA CCCTGTTTAA AAATTTTAAG AAGAAAGCAA 
CCTCAACTCA CGTTTTTCAC AATTACTCTT CAAACCTGCC ATTACCAAAG GATACCACCC 
CATCTCCTTT GGGCTACAGG GTTGAAATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_011239461.1
CDS	466..1155
Translation	MSSETGPVAVDPTLRRRIEPHEFEVFFDPRELRKETCLLYEINWGGRHSVWRHTSQNTSNHVEVNFLEKFTTERYFRPNTRCSITWFLSWSPCGECSRAITEFLSRHPYVTLFIYIARLYHHTDQRNRQGLRDLISSGVTIQIMTEQEYCYCWRNFVNYPPSNEAYWPRYPHLWVKLYVLELYCIILGLPPCLKILRRKQPQLTFFTITLQTCHYQRIPPHLLWATGLK

Target ORF information:

RefSeq Version	XM_011241159.3
Organism	Mus musculus(house mouse)
Definition	Mus musculus apolipoprotein B mRNA editing enzyme, catalytic polypeptide 1 (Apobec1), transcript variant X2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_011241159.3

ORF Insert Sequence:

ATGAGTTCCG AGACAGGCCC TGTAGCTGTT GATCCCACTC TGAGGAGAAG AATTGAGCCC 
CACGAGTTTG AAGTCTTCTT TGACCCCCGG GAGCTTCGGA AAGAGACCTG TCTGCTGTAT 
GAGATCAACT GGGGTGGAAG GCACAGTGTC TGGCGACACA CGAGCCAAAA CACCAGCAAC 
CACGTTGAAG TCAACTTCTT AGAAAAATTT ACTACAGAAA GATACTTTCG TCCGAACACC 
AGATGCTCCA TTACCTGGTT CCTGTCCTGG AGTCCCTGCG GGGAGTGCTC CAGGGCCATT 
ACAGAGTTTC TGAGCCGACA CCCCTATGTA ACTCTGTTTA TTTACATAGC ACGGCTTTAT 
CACCACACGG ATCAGCGAAA CCGCCAAGGA CTCAGGGACC TTATTAGCAG CGGTGTGACT 
ATCCAGATCA TGACAGAGCA AGAGTATTGT TACTGCTGGA GGAATTTCGT CAACTACCCC 
CCTTCAAACG AAGCTTATTG GCCAAGGTAC CCCCATCTGT GGGTGAAACT GTATGTACTG 
GAGCTCTACT GCATCATTTT AGGACTTCCA CCCTGTTTAA AAATTTTAAG AAGAAAGCAA 
CCTCAACTCA CGTTTTTCAC AATTACTCTT CAAACCTGCC ATTACCAAAG GATACCACCC 
CATCTCCTTT GGGCTACAGG GTTGAAATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Apobec1 ( XM_006505401.3 ) cDNA ORF clone, Mus musculus(house mouse) -> XP_006505464.1 Mus musculus apolipoprotein B mRNA editing enzyme, catalytic polypeptide 1 (Apobec1), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OMu16016
Clone ID Related Accession (Same CDS sequence)	XM_006505401.2 , XM_011241159.3 , XM_011241159.2 , NM_001134391.1 , XM_006505401.3 , NM_031159.3
Accession Version	XM_006505401.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 690bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-08-07
Organism	Mus musculus(house mouse)
Product	C->U-editing enzyme APOBEC-1 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000072.6) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Aug 8, 2019 this sequence version replaced XM_006505401.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Mus musculus Annotation Release 108 Annotation Version :: 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGAGTTCCG AGACAGGCCC TGTAGCTGTT GATCCCACTC TGAGGAGAAG AATTGAGCCC 
CACGAGTTTG AAGTCTTCTT TGACCCCCGG GAGCTTCGGA AAGAGACCTG TCTGCTGTAT 
GAGATCAACT GGGGTGGAAG GCACAGTGTC TGGCGACACA CGAGCCAAAA CACCAGCAAC 
CACGTTGAAG TCAACTTCTT AGAAAAATTT ACTACAGAAA GATACTTTCG TCCGAACACC 
AGATGCTCCA TTACCTGGTT CCTGTCCTGG AGTCCCTGCG GGGAGTGCTC CAGGGCCATT 
ACAGAGTTTC TGAGCCGACA CCCCTATGTA ACTCTGTTTA TTTACATAGC ACGGCTTTAT 
CACCACACGG ATCAGCGAAA CCGCCAAGGA CTCAGGGACC TTATTAGCAG CGGTGTGACT 
ATCCAGATCA TGACAGAGCA AGAGTATTGT TACTGCTGGA GGAATTTCGT CAACTACCCC 
CCTTCAAACG AAGCTTATTG GCCAAGGTAC CCCCATCTGT GGGTGAAACT GTATGTACTG 
GAGCTCTACT GCATCATTTT AGGACTTCCA CCCTGTTTAA AAATTTTAAG AAGAAAGCAA 
CCTCAACTCA CGTTTTTCAC AATTACTCTT CAAACCTGCC ATTACCAAAG GATACCACCC 
CATCTCCTTT GGGCTACAGG GTTGAAATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006505464.1
CDS	2324..3013
Translation	MSSETGPVAVDPTLRRRIEPHEFEVFFDPRELRKETCLLYEINWGGRHSVWRHTSQNTSNHVEVNFLEKFTTERYFRPNTRCSITWFLSWSPCGECSRAITEFLSRHPYVTLFIYIARLYHHTDQRNRQGLRDLISSGVTIQIMTEQEYCYCWRNFVNYPPSNEAYWPRYPHLWVKLYVLELYCIILGLPPCLKILRRKQPQLTFFTITLQTCHYQRIPPHLLWATGLK

Target ORF information:

RefSeq Version	XM_006505401.3
Organism	Mus musculus(house mouse)
Definition	Mus musculus apolipoprotein B mRNA editing enzyme, catalytic polypeptide 1 (Apobec1), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006505401.3

ORF Insert Sequence:

ATGAGTTCCG AGACAGGCCC TGTAGCTGTT GATCCCACTC TGAGGAGAAG AATTGAGCCC 
CACGAGTTTG AAGTCTTCTT TGACCCCCGG GAGCTTCGGA AAGAGACCTG TCTGCTGTAT 
GAGATCAACT GGGGTGGAAG GCACAGTGTC TGGCGACACA CGAGCCAAAA CACCAGCAAC 
CACGTTGAAG TCAACTTCTT AGAAAAATTT ACTACAGAAA GATACTTTCG TCCGAACACC 
AGATGCTCCA TTACCTGGTT CCTGTCCTGG AGTCCCTGCG GGGAGTGCTC CAGGGCCATT 
ACAGAGTTTC TGAGCCGACA CCCCTATGTA ACTCTGTTTA TTTACATAGC ACGGCTTTAT 
CACCACACGG ATCAGCGAAA CCGCCAAGGA CTCAGGGACC TTATTAGCAG CGGTGTGACT 
ATCCAGATCA TGACAGAGCA AGAGTATTGT TACTGCTGGA GGAATTTCGT CAACTACCCC 
CCTTCAAACG AAGCTTATTG GCCAAGGTAC CCCCATCTGT GGGTGAAACT GTATGTACTG 
GAGCTCTACT GCATCATTTT AGGACTTCCA CCCTGTTTAA AAATTTTAAG AAGAAAGCAA 
CCTCAACTCA CGTTTTTCAC AATTACTCTT CAAACCTGCC ATTACCAAAG GATACCACCC 
CATCTCCTTT GGGCTACAGG GTTGAAATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Role of angiopoietin-like 3 (ANGPTL3) in regulating plasma level of low-density lipoprotein cholesterol.
Atherosclerosis268196-206(2018 Jan)
Xu YX,Redon V,Yu H,Querbes W,Pirruccello J,Liebow A,Deik A,Trindade K,Wang X,Musunuru K,Clish CB,Cowan C,Fizgerald K,Rader D,Kathiresan S

Loss of APOBEC1 RNA-editing function in microglia exacerbates age-related CNS pathophysiology.
Proceedings of the National Academy of Sciences of the United States of America114(50)13272-13277(2017 Dec)
Cole DC,Chung Y,Gagnidze K,Hajdarovic KH,Rayon-Estrada V,Harjanto D,Bigio B,Gal-Toth J,Milner TA,McEwen BS,Papavasiliou FN,Bulloch K

Do Gametes Woo? Evidence for Their Nonrandom Union at Fertilization.
Genetics207(2)369-387(2017 Oct)
Nadeau JH

A human APOC3 missense variant and monoclonal antibody accelerate apoC-III clearance and lower triglyceride-rich lipoprotein levels.
Nature medicine23(9)1086-1094(2017 Sep)
Khetarpal SA,Zeng X,Millar JS,Vitali C,Somasundara AVH,Zanoni P,Landro JA,Barucci N,Zavadoski WJ,Sun Z,de Haard H,Toth IV,Peloso GM,Natarajan P,Cuchel M,Lund-Katz S,Phillips MC,Tall AR,Kathiresan S,DaSilva-Jardine P,Yates NA,Rader DJ

Development of an efficient screening system to identify novel bone metabolism-related genes using the exchangeable gene trap mutagenesis mouse models.
Scientific reports740692(2017 Jan)
Kurogi S,Sekimoto T,Funamoto T,Ota T,Nakamura S,Nagai T,Nakahara M,Yoshinobu K,Araki K,Araki M,Chosa E

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Apobec1 cDNA ORF clone, Mus musculus(house mouse)

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Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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